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<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GKK8</accession>
    <name>A0A0N8GKK8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_18065</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL69978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064444.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL69978">
        <property type="protein sequence ID" value="KPL69978"/>
        <property type="gene ID" value="ADN00_18065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="117"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL69978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="174" mass="20067" checksum="F11C23611A61A143" modified="2016-01-20" version="1">MNKPNSTPSETIEISLDPQTKSELDEYVGAKNWSLSEGYRIVLGAGLGYLRSNELFETVQEIGIPQDQPSIVARLVRAESSLASMRFRMFELQKANHDWENSLGAIHNQNMGFRSIVKRQKQEIWELNQKMKEMEQQLADIEQLTVCSPRPDTDLTGAQDNQATKWWHRIFKRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GKL7</accession>
    <name>A0A0N8GKL7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_18510</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064528.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18510"/>
    <dbReference type="EnsemblBacteria" id="KPL70050">
        <property type="protein sequence ID" value="KPL70050"/>
        <property type="gene ID" value="ADN00_18510"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="5"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="133"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="133"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL70050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="229" mass="25773" checksum="41C16B24779A003B" modified="2016-01-20" version="1">MPKGLILLVGEEKNTSNLGRLYLDRENFSVLTAEEDSKAFELITTRRPDLVVVDASQPGLDGLDLCRRLRRNDDQPPIVLITEVNQPQQMTAALEAGANEVVSAPVDPRELLARVKAVLRNRADLAETRNGSSDVLRVGDLEFDCARREVMCGHTLLDIRPLEFELLWQLALHRGLVVSRETLIRLVWGPQLSVQTRTVDMHIVRLRRLLKQSRAHIETVTGVGYKLVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GLB7</accession>
    <name>A0A0N8GLB7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_16355</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064112.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72050">
        <property type="protein sequence ID" value="KPL72050"/>
        <property type="gene ID" value="ADN00_16355"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="145"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="171"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="226"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="262"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="290"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="315"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="352"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="380"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="225"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL72050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="428" mass="45080" checksum="864E55462C07F8AA" modified="2016-01-20" version="1">MQPKLSWKKDFFTVWSGQALSILGSQLVQFALIWFLTVKTGSATVLATASLAGMLPGVVLGPFVGTLVDRWNRRKIMIIADSIVAAASIVLALLFMLGVAENWHIFLVMFIRSLAGCFHSNAMSASTSLMVPNQHLTRIQGVNQMLNGGLNIVSAPLGALLLGAIPVEGILAIDVVTAATAVLPLFFIPIPQPERTHPSLTEMETKVTIWQDFNAGIRYMIGWPGLLIASLGTVMINFTIIPAFSLLPLMVKNFFGGSAIQLGYVESAMGIGTIVGGALLGVWGGFPRKIVTAMVGLMGMGIGTLLLALAPSFSLVLAICGAFVVGLMSPITMGPFFAIIQSSVEPEMQARIFSLLGSIGGGMAPIGLMVAGPVADQAGIQAWFFLGGGLCVVMAVAAFFVPVIMNIENGRGSQAPVRSAEIEPAFSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GLC2</accession>
    <name>A0A0N8GLC2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HTH lacI-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_16590</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064158.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16590"/>
    <dbReference type="EnsemblBacteria" id="KPL72090">
        <property type="protein sequence ID" value="KPL72090"/>
        <property type="gene ID" value="ADN00_16590"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="3"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL72090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="340" mass="37794" checksum="7FD7E840575F08B3" modified="2016-01-20" version="1">MAATIKDIAKKIGKTTTTVSRALNDYDDISEETKELVRKAAAELGYIPNTMAQRLQKRQTDTIGLIVPTSGPRFSDPFFSEFIAGIGNTASRRGYDLLVSTRAPGDLELETYRQHIRSHRVDGFIIVRTRHEDERINILRKSGFPFTSFGRANCELDFSFVDEDGEQGMKLVMEYLAKLGHKRFGVISPPSNLEFSRYRLKGIWDKAAELGIAAHDISILEGDLTQRSGYEITNQLLDQPRFPTAIIACNDLMAFGAMSAAQERGLVVGSDVSITGFDNIPMSEYSHPPLTTVNQPIYQIGTTVCEMLIRRIRGETTEVEQILLTPSLIVRQSCGPAPMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GM24</accession>
    <name>A0A0N8GM24_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_13960</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063643.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000033.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74106">
        <property type="protein sequence ID" value="KPL74106"/>
        <property type="gene ID" value="ADN00_13960"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL74106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="159" mass="17067" checksum="63AB41ECB883CCF4" modified="2016-01-20" version="1">MAEIGKDCHITLAHPAVNNGEPVGFLLDEEENEHGALVSVQRETDSNGQTRVRLFFDVLLAERLVNPDGSAHAASREEMYAALNAYLRQTSGVAVACSAGVFANVGALGYSAAEMHYPRLTVVACQLNNAGPYFAAVAQSVYDNAVWDGVLAWDAAVWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GM57</accession>
    <name>A0A0N8GM57_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Redox-sensing transcriptional repressor Rex</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rex</name>
        <name evidence="8" type="ORF">ADN00_13850</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the transcriptional regulatory Rex family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063615.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000032.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13850"/>
    <dbReference type="EnsemblBacteria" id="KPL74370">
        <property type="protein sequence ID" value="KPL74370"/>
        <property type="gene ID" value="ADN00_13850"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051775">
        <property type="term" value="P:response to redox state"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01131">
        <property type="entry name" value="Rex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009718">
        <property type="entry name" value="Rex_DNA-bd_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022876">
        <property type="entry name" value="Tscrpt_rep_Rex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35786">
        <property type="entry name" value="PTHR35786"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02629">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06971">
        <property type="entry name" value="Put_DNA-bind_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00881">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0678">Repressor</keyword>
    <keyword evidence="5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="CoA_binding" evidence="7">
        <location>
            <begin position="79"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="6">
        <location>
            <begin position="16"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="90"/>
            <end position="95"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL74370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="207" mass="22941" checksum="54303FB70C685B2D" modified="2016-01-20" version="1">MNKVDIPAIIVARLPIYLETLELMYKEGIYKTSSRELGDRIGITAAQIRKDLSQFGEFGKQGTGYSIPNLVAELRKILHVDKIWDVALVGTGNLGTAIARYPEFNHRGFRIVMCFDSDPALIGTKVGDITIEDSATMIERIREANIKIAMLTVPGSIAQQVADDLVKAGVTAILNYAPVALNMPPDIIHVQHIDPILQLQQMTYYMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GN17</accession>
    <name>A0A0N8GN17_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_09600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062784.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76850">
        <property type="protein sequence ID" value="KPL76850"/>
        <property type="gene ID" value="ADN00_09600"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2375"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025352">
        <property type="entry name" value="DUF4256"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14066">
        <property type="entry name" value="DUF4256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="191" mass="21355" checksum="15E01814BE709013" modified="2016-01-20" version="1">MNTKTSPPNVLSPEQGEALLKTLKARFEKNMRRHPGVAWAAVQAKLQDKPEKLWSLNEMERTGGEPDVTGQDDQTGEILFIDCSAETPAGRRNLCYDGEALQSRKENKPQDSALDVAAAMGIELLSEEQYRALQQLGEFDLKTSSWLKTPPAIRKLGGAIFGDRRYDHVFVYHNGASSYYAVRGFRGLLRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GN33</accession>
    <name>A0A0N8GN33_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10385</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062931.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10385"/>
    <dbReference type="EnsemblBacteria" id="KPL76978">
        <property type="protein sequence ID" value="KPL76978"/>
        <property type="gene ID" value="ADN00_10385"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008407">
        <property type="entry name" value="Brnchd-chn_aa_trnsp_AzlD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05437">
        <property type="entry name" value="AzlD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="109" mass="11943" checksum="20FEF6DBB08910CC" modified="2016-01-20" version="1">MDQQRVLIGLFGMLLVTYLPRVLPVLYLAGRTLPRAVEVWLRYVPPAVLAAMLLPALVMPNGTLDLSLNNLYWLAAIPAFGVAWKTRSLFAPVLTGMALVALARLLGWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNR3</accession>
    <name>A0A0N8GNR3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">MFS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_06250</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. TCR/Tet family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062104.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78818">
        <property type="protein sequence ID" value="KPL78818"/>
        <property type="gene ID" value="ADN00_06250"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001958">
        <property type="entry name" value="Tet-R_TetA/multi-R_MdtG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01035">
        <property type="entry name" value="TCRTETA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="76"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="147"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="170"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="217"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="253"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="342"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="370"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="7">
        <location>
            <begin position="10"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL78818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="409" mass="44359" checksum="6F5BD4CE74F3CAE7" modified="2016-01-20" version="1">MPGKNSPTSILSILQRSIFIISLPFFLLSLILPVYGKEIGASVVEIGLFYSAFSFVTVILRPLVGLGLDRAGRRTFFLAGLGGYALTMLSFALISQVWGLVLARIIQGIASSLMWLSASAIISDVAGEDQRARSFGKITQSSSQGSILGTFLGFFLLGTASNLLPDHSTMSSWALLFLFFCLTSLPALFLALRTLPETKPLHETQPKDTPIQWSRPWVLLLMVTFVTGMSVSMISPVLIIFLQERLGVGIDTLSWAFLPMGLVWAFLPAQFGKWADRIGRKPMMLAGLAAAALSSFIVPYLGSVIALSVIWAFQAMCYAAGDPAEQALVADLTGRQQRGRAYGFYLMCADLGATIGPLGGTWLYQTYGEAIPFYVNGIILAVCALVLWAFLRIPSSPKSEQEMDQPVTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNW5</accession>
    <name>A0A0N8GNW5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Guanylate kinase</fullName>
            <ecNumber evidence="2">2.7.4.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">GMP kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">gmk</name>
        <name evidence="10" type="ORF">ADN00_04085</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the guanylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.8" evidence="2"/>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04085"/>
    <dbReference type="EnsemblBacteria" id="KPL79234">
        <property type="protein sequence ID" value="KPL79234"/>
        <property type="gene ID" value="ADN00_04085"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.172"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004385">
        <property type="term" value="F:guanylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008145">
        <property type="entry name" value="GK/Ca_channel_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008144">
        <property type="entry name" value="Guanylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017665">
        <property type="entry name" value="Guanylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020590">
        <property type="entry name" value="Guanylate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00625">
        <property type="entry name" value="Guanylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00072">
        <property type="entry name" value="GuKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03263">
        <property type="entry name" value="guanyl_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00856">
        <property type="entry name" value="GUANYLATE_KINASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50052">
        <property type="entry name" value="GUANYLATE_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Guanylate kinase-like" evidence="9">
        <location>
            <begin position="10"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00030128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL79234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="203" mass="23313" checksum="E1416BD0148650F1" modified="2016-01-20" version="1">MNFNVLKPEPLLIVISGPSGIGKDAVVKELQKRDLPLHFVITATTRPKRSEETHGVDYFFVSTEEFETMIAQDELIEYAEVYQQYKGVPKAQVRAALQSGKDVIMRLDVQGAQKIRDLCPQAVLIFLIPTDTQEWINRLLARNTETSEDFSLRIETARKELEYLPIFDYIVLNAHNCLQQAVDTIEQIIHTEHHRVVPRKITL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNZ1</accession>
    <name>A0A0N8GNZ1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">YlxR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_02705</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000012">
        <property type="protein sequence ID" value="KPL79442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061421.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000012.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02705"/>
    <dbReference type="EnsemblBacteria" id="KPL79442">
        <property type="protein sequence ID" value="KPL79442"/>
        <property type="gene ID" value="ADN00_02705"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2369"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007393">
        <property type="entry name" value="DUF448"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037465">
        <property type="entry name" value="YlxR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035931">
        <property type="entry name" value="YlxR-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34215">
        <property type="entry name" value="PTHR34215"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04296">
        <property type="entry name" value="YlxR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64376">
        <property type="entry name" value="SSF64376"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YlxR" evidence="1">
        <location>
            <begin position="15"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="102" mass="11426" checksum="08BA5A58771722CF" modified="2016-01-20" version="1">MNKQKGKRVRHIPQRTCVGCRQINDKRELVRVVRTPEGVQIDRTGKLAGRGAYLHALRSCWIKGLKGALANALKTQLSSQDQALLESFLAELPEESELEETS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GP69</accession>
    <name>A0A0N8GP69_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_01990</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000007">
        <property type="protein sequence ID" value="KPL80066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061289.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000007.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80066">
        <property type="protein sequence ID" value="KPL80066"/>
        <property type="gene ID" value="ADN00_01990"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL80066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="165" mass="18974" checksum="79C21015DEAF0DAD" modified="2016-01-20" version="1">MRLGDVFKAGQDDELYQVLGVDIFGRVLARRFELEHGEVGAQVEFEPGPGCRVLFNAYDSVEIERGCEVCEMTYQVEFSERGDWSGELWFEAVSLQGDGSQTALMTSPRAAFTRGNNWPNPEIPDNHKVHQQLCQMLEAAGWQLILERRSWWWKCRFKRPCGEGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WMK0</accession>
    <name>A0A0P6WMK0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sulfurtransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_18225</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064477.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18225"/>
    <dbReference type="EnsemblBacteria" id="KPL70003">
        <property type="protein sequence ID" value="KPL70003"/>
        <property type="gene ID" value="ADN00_18225"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="30"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="132" mass="15329" checksum="7EACCF8B2D7D5D8E" modified="2016-01-20" version="1">MNNLNELLRSMTFDFFGSGKHKIEMEALLAMQDAVFLDVRSRQEYESLQIRLEHHIRVLWIPIDEIPDRYAEIPRDQTVGIFCSAGTRSTIVYLYLRSLGYENVRIAPSNYDAITSQLMPGKLYKAIQQSQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WMV0</accession>
    <name>A0A0P6WMV0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Acetohydroxy-acid isomeroreductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">ADN00_19085</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 2/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 2/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 9">Belongs to the ketol-acid reductoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064633.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_19085"/>
    <dbReference type="EnsemblBacteria" id="KPL70140">
        <property type="protein sequence ID" value="KPL70140"/>
        <property type="gene ID" value="ADN00_19085"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3130"/>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00056"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004455">
        <property type="term" value="F:ketol-acid reductoisomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013023">
        <property type="entry name" value="KARI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000506">
        <property type="entry name" value="KARI_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013116">
        <property type="entry name" value="KARI_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21371">
        <property type="entry name" value="PTHR21371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01450">
        <property type="entry name" value="IlvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07991">
        <property type="entry name" value="IlvN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00465">
        <property type="entry name" value="ilvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51851">
        <property type="entry name" value="KARI_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51850">
        <property type="entry name" value="KARI_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 9" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="KARI N-terminal Rossmann" evidence="10">
        <location>
            <begin position="9"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="KARI C-terminal knotted" evidence="11">
        <location>
            <begin position="201"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="209"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="249"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="271"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00032744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KPL70140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="351" mass="38643" checksum="9EFBA7E1BC86C716" modified="2016-01-20" version="1">MAKMVFGGVTEDVVTRDEFPLEKAREVLKDEVVAVLGYGVQGPAQSLNMRDNGIHVIIGQEPSDKFYWDKAVKDGWVPGETLFSLEEAAARGTIIQYLVSDAAQMMVWDRLKPHLTTGKALYFSHGFGIVYKDQTGIIPPADIDVILVAPKGSGTSVRANFLSGSGINSSYAVHQDYTGRAEERTLAVGIAVGSGYLFPTTFENEVYSDLTGERGVLMGALAGVMEAQYETLRRHGHSPSEAFNETVEELTQSLIRLVAANGMDWMYANCSTTAQRGALDWAPRFKAAVEPTFEQLYQSVLSGEETRVVLAANSAPDYREKLGEELRVMRESEMWQTGAAVRSLRPENWNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WPJ9</accession>
    <name>A0A0P6WPJ9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FeoB-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_15930</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL71990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15930"/>
    <dbReference type="EnsemblBacteria" id="KPL71990">
        <property type="protein sequence ID" value="KPL71990"/>
        <property type="gene ID" value="ADN00_15930"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3619"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030389">
        <property type="entry name" value="G_FEOB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02421">
        <property type="entry name" value="FeoB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51711">
        <property type="entry name" value="G_FEOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FeoB-type G" evidence="1">
        <location>
            <begin position="1"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL71990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="131" mass="14221" checksum="9F18BE42D5A90FE6" modified="2016-01-20" version="1">MEVSRADCIYGNGEVELIDLPGTYSLAAYSLEEVIARDFLLDEKPDVVICVVDAANLERNLYLTVQVLELGFPIVLALNMVDVTEAAGIRIDEEKIGQALQCPVIRTIARDGKGVKELIEAAVCAARSKAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WPR5</accession>
    <name>A0A0P6WPR5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_16435</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064128.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16435"/>
    <dbReference type="EnsemblBacteria" id="KPL72063">
        <property type="protein sequence ID" value="KPL72063"/>
        <property type="gene ID" value="ADN00_16435"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GAF" evidence="1">
        <location>
            <begin position="38"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="HATPase_c" evidence="2">
        <location>
            <begin position="301"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL72063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="405" mass="45437" checksum="CCBB0CE1B1A086B9" modified="2016-01-20" version="1">MNHNEQTFTFEEMAELERRRLVADSLRGTLAVLNSNLSLEKLLNYIVNQACPLLNADAAAIYHLQLNGVLTTQALVGLSSDYVQYANIPLGKLATGKAALSRQPIYFADTKQLLQDNVDPNLRDAIEILTRKFKSILSVPIEIRDENYGSLTLYYKENHDISDEEIALAKDFSIQAALAIDNARLRMRVQQDAIVEERNRLARELHDSVTQNLFSASLIAETLPKLIARDPEKTLEGLNELCLLTRGALAEMRSLLLELRPHAMEDVQLDILIRQLSESASGRLRKPVHFSVSGQAMLPMDVRLTFYRVTQEALNNIIKHAAANCVQISLNYGESKMDGTCDWVQLSIEDDGCGFRKMDEKASHLGFSIMKERAQALGAELTIKSQVNCGTQIVLVWKANRQEQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WR66</accession>
    <name>A0A0P6WR66_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SHSP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_16915</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16915"/>
    <dbReference type="EnsemblBacteria" id="KPL71383">
        <property type="protein sequence ID" value="KPL71383"/>
        <property type="gene ID" value="ADN00_16915"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00011">
        <property type="entry name" value="HSP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="SSF49764"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SHSP" evidence="3">
        <location>
            <begin position="36"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL71383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="147" mass="16361" checksum="E1262AC572DC3EBE" modified="2016-01-20" version="1">MDQLTGECEMTLYLTPIGRRARRMMNLADAQNWANMVESRVAFPIDIKEENDAFVISAMLPGIKAEDLEISVVNEVVSIKGEYQRERGDGEKYLLTELPSGRFCRTINLPDQLDSAKAEASMENGVLTLSIPKAEAARPKTIKVSVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WSU8</accession>
    <name>A0A0P6WSU8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_16685</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72105">
        <property type="protein sequence ID" value="KPL72105"/>
        <property type="gene ID" value="ADN00_16685"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="457" mass="52874" checksum="A5920ABA13D216FF" modified="2016-01-20" version="1">MAVLAKKMPSTMIGIVKPLEVLRNQGQINLRVFTENHVKPWHLNWPDVVVFGRNTEPLFDFVLEGILLNQIPTIFELDDNLWEVPQQLELGKYHRAPERIHQLEKYIACADLVRVYNPHIYARVEKLNPNVKMVKAGVDFRLLPPWPGIYRKPGKIRIAYPTSRIEDDLYSVFIHAVKNILDQYSHQVEFHLWGSIPAELQGLPAVKAHPKILDYNRFLRRFSRMGFEIGLAPLVDNPFSVSKTNNKFREYGASGVAGVYSNIGPYVDSVEDGVTGLLVRNTQEAWQDAIEKLILNPTLRQQIQVNARQVVERDYNQKEVVQTWREDLRTVLGKTKTEWNAKMEIPLRLEQNVWSGLRFHSRLPVYGVLKLEIQTRQHGRPLRAPINQFFSDTKEVEFRFTAVQDAVYKARDIVVTLSGKKSILDLMDWEQTEAVYGEFFEEVTIEETKEETNGEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WSW0</accession>
    <name>A0A0P6WSW0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Asparagine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_16635</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the asparagine synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16635"/>
    <dbReference type="EnsemblBacteria" id="KPL72124">
        <property type="protein sequence ID" value="KPL72124"/>
        <property type="gene ID" value="ADN00_16635"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3770"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004066">
        <property type="term" value="F:asparagine synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006529">
        <property type="term" value="P:asparagine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01991">
        <property type="entry name" value="Asn_Synthase_B_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00712">
        <property type="entry name" value="AsnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006426">
        <property type="entry name" value="Asn_synth_AEB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001962">
        <property type="entry name" value="Asn_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033738">
        <property type="entry name" value="AsnB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00733">
        <property type="entry name" value="Asn_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13537">
        <property type="entry name" value="GATase_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001589">
        <property type="entry name" value="Asn_synthetase_glu-h"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01536">
        <property type="entry name" value="asn_synth_AEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="7">
        <location>
            <begin position="2"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="299"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="372"/>
            <end position="373"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for beta-aspartyl-AMP intermediate formation" evidence="6">
        <location>
            <position position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001589-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL72124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="650" mass="73688" checksum="3470C7A8D1279138" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WT35</accession>
    <name>A0A0P6WT35_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_15705</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72261">
        <property type="protein sequence ID" value="KPL72261"/>
        <property type="gene ID" value="ADN00_15705"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="130" mass="14110" checksum="5ACFFD7C312924B2" modified="2016-01-20" version="1">MTATIRGIQKAQKANSAHIRALRPGGALGLAVQAGLILTHQSAIRKTHVDTGALRASHRMRYEFTAAGPRGVIFIDPNAENPRSGEKTAVYGPIEHARGGEHAFYARVRDEDGPRISRAVAREFLRGFAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WT56</accession>
    <name>A0A0P6WT56_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">POLIIIAc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_15485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15485"/>
    <dbReference type="EnsemblBacteria" id="KPL72297">
        <property type="protein sequence ID" value="KPL72297"/>
        <property type="gene ID" value="ADN00_15485"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004013">
        <property type="entry name" value="PHP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003141">
        <property type="entry name" value="Pol/His_phosphatase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02811">
        <property type="entry name" value="PHP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00481">
        <property type="entry name" value="POLIIIAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="SSF89550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="POLIIIAc" evidence="1">
        <location>
            <begin position="1"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="240" mass="26863" checksum="199E27DED50A0A02" modified="2016-01-20" version="1">MHVHTVLSPCGDIEMIPPLIVEAAIEKGIQLIAITDHNASANIWAVQKAAEGTGLSVLPGMELQTAEDIHCLCLFDTLEQIEMLQHDVDTNLPALENRPDFFGEQFVVDPTGDFIRREHRLLLTSTRLTLKQAFQRVLELGGLFIPAHINRQAFGLMPTLGLIPPDIDLEAVEISRHMKISDAQKKYPQITNIPTIQSGDVHYLEDFLGTTYFKIAHPTIAELRMALKNQNGRMVLIQEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WU20</accession>
    <name>A0A0P6WU20_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 9">Argininosuccinate synthase</fullName>
            <ecNumber evidence="2 9">6.3.4.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">Citrulline--aspartate ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">argG</name>
        <name evidence="10" type="ORF">ADN00_14410</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10932"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57472"/>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.4.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the argininosuccinate synthase family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.5" evidence="2 9"/>
    <dbReference type="EMBL" id="LGCL01000034">
        <property type="protein sequence ID" value="KPL73755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063727.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000034.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14410"/>
    <dbReference type="EnsemblBacteria" id="KPL73755">
        <property type="protein sequence ID" value="KPL73755"/>
        <property type="gene ID" value="ADN00_14410"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1402"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00113"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004055">
        <property type="term" value="F:argininosuccinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01999">
        <property type="entry name" value="Argininosuccinate_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00005">
        <property type="entry name" value="Arg_succ_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001518">
        <property type="entry name" value="Arginosuc_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018223">
        <property type="entry name" value="Arginosuc_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023434">
        <property type="entry name" value="Arginosuc_synth_type_1_subfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024074">
        <property type="entry name" value="AS_cat/multimer_dom_body"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11587">
        <property type="entry name" value="PTHR11587"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00764">
        <property type="entry name" value="Arginosuc_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69864">
        <property type="entry name" value="SSF69864"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00032">
        <property type="entry name" value="argG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00564">
        <property type="entry name" value="ARGININOSUCCIN_SYN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00565">
        <property type="entry name" value="ARGININOSUCCIN_SYN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3 9" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="13"/>
            <end position="21"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>L-citrulline</name>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>L-citrulline</name>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="127"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>L-citrulline</name>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>L-citrulline</name>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>L-citrulline</name>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="265"/>
        </location>
        <ligand>
            <name>L-citrulline</name>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="277"/>
        </location>
        <ligand>
            <name>L-citrulline</name>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL73755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="418" mass="46227" checksum="3A34329FE1352FCD" modified="2016-01-20" version="1">MAADKKANKVVLAYSGGLDTSVIIPWLIENYGCEVICFAADVGQAEELDNLEARALQSGASKLIIGDLKEEFAKDYLFPMIHSGALYERKYFLGTSIARPVIAKHLVQVAEQEGADAIAHGCTGKGNDQVRFELAIMALNPTLKVIAPWREWDITSREDALAYLEAHNIPFPNNNPGLYSRDRNLWHISHEGGKLENLANAPDDSMFMLSNSPKSAPDEPETVEIAFENGNPVAIDGVSYSPAQIVMKLNALGGKHGIGRVDMVENRLVGMKSRGVYETPGGTILYAAHQELESITLDRETMHMKDTLSLQYAKLVYFGQWFTPLREAFDAFFSVTQKAVTGKITLQLYKGNVIVIKRSSPYSLYREEYATFGPSPVYDQSDAAGFIRLFGLSSKVQALIQMDDVKVPQVPIEEIVRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WVZ5</accession>
    <name>A0A0P6WVZ5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Branched-chain-amino-acid aminotransferase</fullName>
            <shortName evidence="17">BCAT</shortName>
            <ecNumber evidence="17">2.6.1.42</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="primary">ilvE</name>
        <name evidence="18" type="ORF">ADN00_19050</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 17">Acts on leucine, isoleucine and valine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2-oxoglutarate + L-isoleucine = (S)-3-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24801"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:35146"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>2-oxoglutarate + L-leucine = 4-methyl-2-oxopentanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:18321"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:17865"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>2-oxoglutarate + L-valine = 3-methyl-2-oxobutanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24813"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="EC" id="2.6.1.42"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4 16">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6 17">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 4/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8 17">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 4/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7 17">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 4/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9 15">Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.42" evidence="17"/>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064626.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_19050"/>
    <dbReference type="EnsemblBacteria" id="KPL70133">
        <property type="protein sequence ID" value="KPL70133"/>
        <property type="gene ID" value="ADN00_19050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3123"/>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00058"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00073"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00062"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052656">
        <property type="term" value="F:L-isoleucine transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052654">
        <property type="term" value="F:L-leucine transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050048">
        <property type="term" value="F:L-leucine:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052655">
        <property type="term" value="F:L-valine transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01557">
        <property type="entry name" value="BCAT_beta_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018300">
        <property type="entry name" value="Aminotrans_IV_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005785">
        <property type="entry name" value="B_amino_transI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033939">
        <property type="entry name" value="BCAT_family"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="SSF56752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01122">
        <property type="entry name" value="ilvE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00770">
        <property type="entry name" value="AA_TRANSFER_CLASS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 17" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 17 18" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="14 17" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="13 16" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12 17 18" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00003109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00004824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00004931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00005072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00009320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU004106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU004516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="RuleBase" id="RU364094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KPL70133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="306" mass="33885" checksum="B7024BD276358B8F" modified="2016-01-20" version="1">MSLESKYIWLNGKLVETEKATIHFLNTSLHYGVGAFEGIRCYDTPKGPAIFRLTEHSQRLINSAKVMGFNTLPYSLQEIDRATLDVVAANGFKECYIRPLLYLSAPNLGLNLDTATPQLGIAAWEWGSYLGPEALEKGIRANISSFTRLHPNVNMTKAKITGNYANSMLAKTESVRLGFDEAIMLDPQGYVGECTGENIFVVRDGKIYTPPTTTILEGITRDTLITIATEMGFEIIEQPISRDQLYIADEVFVCGSAAECVPLWEIDHRVIGSGQGGPITRKIQQAYQAAIHGQNDAYAQWLHYVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WWK8</accession>
    <name>A0A0P6WWK8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_18000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000044">
        <property type="protein sequence ID" value="KPL70769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064432.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000044.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18000"/>
    <dbReference type="EnsemblBacteria" id="KPL70769">
        <property type="protein sequence ID" value="KPL70769"/>
        <property type="gene ID" value="ADN00_18000"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025139">
        <property type="entry name" value="DUF4062"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13271">
        <property type="entry name" value="DUF4062"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05729">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NACHT" evidence="1">
        <location>
            <begin position="353"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="482" mass="54450" checksum="994CF2CAE955623C" modified="2016-01-20" version="1">MSQTAHVFRIFVSSTFSDLKAERNALQARVFPRLREFAETYGCHFQVIDLRWGVSEEASLDQQAMNICLEEIARCQQTSPRPNFIVLLGDRYGWMPPLAQIPDDEFQQILELVNGDDRVFLEAWYVLDGNAVDPEWRLRPRKKGGPYELYIAWQPVEVRLQRILAAAVRQLGLPDDRFLAYTTSATEQEIAAGALRVKDAPEHVLCFFRHIEELPPEFDKAARDFRDQDEQSQTVDRAAHDRQDALKEQLAAYVPGNVYRYQARWTGSGITINHIDQLCQDVYESLERIILTQIARPRVGDAHEGPVHIRPDDVLDEEGRAHWEFAEKRLRFFVGRTNILKQIAGHLKEGGHHTLAVVGGGGTGKSALLARAVEQAQEMHPNAQVVYRFIGVTPGSSDGRGLLESLCREISRRYGSDESDIPLDYRDLVPELAKAMRLANSENPLILFLDSLDQLAASQGARGLIWLPAELPDHVAAIVSTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZ52</accession>
    <name>A0A0P6WZ52_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Beta-glucosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_16305</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064103.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16305"/>
    <dbReference type="EnsemblBacteria" id="KPL72044">
        <property type="protein sequence ID" value="KPL72044"/>
        <property type="gene ID" value="ADN00_16305"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3698"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102483">
        <property type="term" value="F:scopolin beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019800">
        <property type="entry name" value="Glyco_hydro_3_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="SSF52279"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00775">
        <property type="entry name" value="GLYCOSYL_HYDROL_F3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fn3_like" evidence="4">
        <location>
            <begin position="321"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL72044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="927" mass="102745" checksum="6901E89C75FA64B4" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZJ2</accession>
    <name>A0A0P6WZJ2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_15545</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063946.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72232">
        <property type="protein sequence ID" value="KPL72232"/>
        <property type="gene ID" value="ADN00_15545"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="133" mass="15055" checksum="FC569082834DCC1F" modified="2016-01-20" version="1">MATNNVYRTILLTMPPGVEQRIMEILIRHVGSENRIKRRDLVFAVFGRVDQKPAQTSTLDRQVRSAIARMQERGIPILSDSGQGGYWLGTKAECVNFIKEQQDRQAALARKINGIKKLWKISPNDLQARLPGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X1C0</accession>
    <name>A0A0P6X1C0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">50S ribosomal protein L30</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpmD</name>
        <name evidence="8" type="ORF">ADN00_12515</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2 5">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uL30 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063352.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12515"/>
    <dbReference type="EnsemblBacteria" id="KPL76150">
        <property type="protein sequence ID" value="KPL76150"/>
        <property type="gene ID" value="ADN00_12515"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3984"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01658">
        <property type="entry name" value="Ribosomal_L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01371_B">
        <property type="entry name" value="Ribosomal_L30_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036919">
        <property type="entry name" value="L30_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005996">
        <property type="entry name" value="Ribosomal_L30_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018038">
        <property type="entry name" value="Ribosomal_L30_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016082">
        <property type="entry name" value="Ribosomal_L30_ferredoxin-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15892">
        <property type="entry name" value="PTHR15892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00327">
        <property type="entry name" value="Ribosomal_L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002211">
        <property type="entry name" value="Ribosomal_L30_bac-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55129">
        <property type="entry name" value="SSF55129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01308">
        <property type="entry name" value="rpmD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00634">
        <property type="entry name" value="RIBOSOMAL_L30"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_L30" evidence="7">
        <location>
            <begin position="10"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL76150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="67" mass="7558" checksum="7B1E4AA6BC7E3441" modified="2016-01-20" version="1">MAKKSEPKKLRITLVRSVIGNTEKHKATVRALGLHKINQSVVQEDSATLQGMLRKINHLVKVEEQVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X1J5</accession>
    <name>A0A0P6X1J5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptide chain release factor 2</fullName>
            <shortName evidence="4">RF-2</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">prfB</name>
        <name evidence="7" type="ORF">ADN00_14805</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Peptide chain release factor 2 directs the termination of translation in response to the peptide chain termination codons UGA and UAA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="4">Methylated by PrmC. Methylation increases the termination efficiency of RF2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the prokaryotic/mitochondrial release factor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000036">
        <property type="protein sequence ID" value="KPL73104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14805"/>
    <dbReference type="EnsemblBacteria" id="KPL73104">
        <property type="protein sequence ID" value="KPL73104"/>
        <property type="gene ID" value="ADN00_14805"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1824"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016149">
        <property type="term" value="F:translation release factor activity, codon specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00094">
        <property type="entry name" value="Rel_fac_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005139">
        <property type="entry name" value="PCRF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045853">
        <property type="entry name" value="Pep_chain_release_fac_I_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004374">
        <property type="entry name" value="PrfB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03462">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00472">
        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00937">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75620">
        <property type="entry name" value="SSF75620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00020">
        <property type="entry name" value="prfB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0488">Methylation</keyword>
    <keyword evidence="3 4" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCRF" evidence="6">
        <location>
            <begin position="26"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="234"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="modified residue" description="N5-methylglutamine" evidence="4">
        <location>
            <position position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL73104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="309" mass="35539" checksum="54D41D7C7287C04E" modified="2016-01-20" version="1">MKKIAELREEIESWEGLHRRIRDSLELAEMEDESLRVELEAETLIFEKEIEKRELDTLLSGRHDKGNAILAIHAGAGGTDSQDWAGMLERMYLRWAEKHNFQTETLDYTEGEEAGLKSATIAINGRFAYGYLRAEKGVHRLVRLSPFDSAHRRHTSFAQVEVLPEVTDDDDAIQIDPNDLRIDIYRSSGAGGQNVQKNATAVRITHIPSGLVVSCQNERSQLQNRENAMRVLRSRLLEKHREEQEKQMAELRGEYQKAEWGSQIRSYVLHPYQMVKDHRTNFEMGNSQAVLDGDLDGFIEAYLRMSRNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-08-12" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X207</accession>
    <name>A0A0P6X207_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cupin_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_11310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063122.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76543">
        <property type="protein sequence ID" value="KPL76543"/>
        <property type="gene ID" value="ADN00_11310"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="1">
        <location>
            <begin position="51"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="124" mass="13816" checksum="D604BA1EC2EA15C7" modified="2016-01-20" version="1">MSSIHRFNGEGTQFEWEGVPVRDYGASGFEGVVKHVLIGEDDGAPNFVVRYFQVAPGKASRLEQHPHEHGVVILQGRARVQINDDFYELGEKDAIFISGNDLHQLTALGDEPLGFICVIPRKDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X2M4</accession>
    <name>A0A0P6X2M4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_09990</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062857.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09990"/>
    <dbReference type="EnsemblBacteria" id="KPL76918">
        <property type="protein sequence ID" value="KPL76918"/>
        <property type="gene ID" value="ADN00_09990"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2459"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="327" mass="35655" checksum="2E27E4975BEA6699" modified="2016-01-20" version="1">MTWFKELTGFNETDASDVRQKLILDGETLTSTVNGRRLVCGRLETPSLGDLRQRARANQSNRGRLTAREVIADVRDLHANVENAGALFQVASQFNLLEMVSPSVTPEDGISRYENDHTQGPACAVAAGAGTIFRNYFAPVNGQTGQTAHNQIDCLADLGRALGNSDSRLWQMKNGYALATAQGLDEIATRLRAASETERDSLRQLLRIGLQWNTQVTLPNCAHLVTQAYCAALPVAYGPEPAERWEAFARLVLEAAYEATLCAAVLNARPRAYLTLLGGGVFGNQPEWILDALHRALQIFAASNLEISIVSYGRSNPAVQAMLEQLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5W2</accession>
    <name>A0A0P6X5W2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_06745</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000018">
        <property type="protein sequence ID" value="KPL78417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062218.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000018.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06745"/>
    <dbReference type="EnsemblBacteria" id="KPL78417">
        <property type="protein sequence ID" value="KPL78417"/>
        <property type="gene ID" value="ADN00_06745"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2261"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001670">
        <property type="entry name" value="ADH_Fe/GldA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018211">
        <property type="entry name" value="ADH_Fe_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039697">
        <property type="entry name" value="Alcohol_dehydrogenase_Fe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496">
        <property type="entry name" value="PTHR11496"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00465">
        <property type="entry name" value="Fe-ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00060">
        <property type="entry name" value="ADH_IRON_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-ADH" evidence="2">
        <location>
            <begin position="9"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="382" mass="40957" checksum="D2BBFB17A7ED7D04" modified="2016-01-20" version="1">MELRKFVAPEIVYGIGARDMAARYAHNFGGRKVLVVTDEGVIRAGWVDALLANLREAGLSSTVFSDVSPNPRDSQVMAGAELFLRENCNLIIAIGGGSPMDCAKGIGIVSYNQRSILDFEGVDEVPIPGPPLICIPTTAGSAADISQFAIINDTRRKVKIAIISKTVVPDVALIDPVTTTTKDAYLTACTGMDALTHAFEAYVSNAASSITDLHALEAIRIAWRALPALFKDLKNLDLRNQMMLACMHAGLAFSNASLGIVHAMAHSLGGYLDLAHGECNALLLEFAVEYNFDQASGRYLDIARAMGLDLAALPPAEQRAEIIQALRQFRRQVGIEGSLHEIGVSMSDLNALAGKAVHDPCIATNPKPVQLANIEEIYGRAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X6T1</accession>
    <name>A0A0P6X6T1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ADN00_11745</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063207.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11745"/>
    <dbReference type="EnsemblBacteria" id="KPL76027">
        <property type="protein sequence ID" value="KPL76027"/>
        <property type="gene ID" value="ADN00_11745"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3825"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="32"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="75"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="173"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="252"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="282"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="39"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="352"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="385"/>
            <end position="392"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL76027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="601" mass="66834" checksum="FD2FFE43D8AD8142" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X6U6</accession>
    <name>A0A0P6X6U6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_08650</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000022">
        <property type="protein sequence ID" value="KPL77655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062596.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000022.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77655">
        <property type="protein sequence ID" value="KPL77655"/>
        <property type="gene ID" value="ADN00_08650"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL77655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="334" mass="37160" checksum="2E80F063833CDA51" modified="2016-01-20" version="1">MFKENHINIRSLAWHDLITLYRRRDQVLLLDSAALLTRGNAIGLSAMLDYLNPNRGIFTGVYAANNAQESLIGQIQFTLGERAAHLAFLLSDDAPDPARLAFLLDGLVHKAGELGAYSLVAELPEDSLLFVRLRRAGFVVYGWQQVWQLPIQEHVDTSKGGFWRAISSADEFHVRSLYQSLVPSLVQCAEVFNDHQLNGLVYEQNGEISAYVEGVSGPRGFYVNPLIHPSVEDVNQLIQSLPGQLQPLMGRPVYLAVRSYQGWLEAVLSQMGAQLYERYALLVKYFTLPQRSAVPAAARAVMENPNAKPAAPIMNHFLEPKSEPARLTGHGNKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X6V8</accession>
    <name>A0A0P6X6V8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Methionine--tRNA ligase</fullName>
            <ecNumber evidence="10">6.1.1.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Methionyl-tRNA synthetase</fullName>
            <shortName evidence="10">MetRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">metG</name>
        <name evidence="14" type="ORF">ADN00_11930</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 10">Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP + L-methionine + tRNA(Met) = AMP + diphosphate + L-methionyl-tRNA(Met)</text>
            <dbReference type="Rhea" id="RHEA:13481"/>
            <dbReference type="Rhea" id="RHEA-COMP:9667"/>
            <dbReference type="Rhea" id="RHEA-COMP:9698"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78530"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="10">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the class-I aminoacyl-tRNA synthetase family. MetG type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.10" evidence="10"/>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063243.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11930"/>
    <dbReference type="EnsemblBacteria" id="KPL76054">
        <property type="protein sequence ID" value="KPL76054"/>
        <property type="gene ID" value="ADN00_11930"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3862"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004825">
        <property type="term" value="F:methionine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006431">
        <property type="term" value="P:methionyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07957">
        <property type="entry name" value="Anticodon_Ia_Met"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00814">
        <property type="entry name" value="MetRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00098">
        <property type="entry name" value="Met_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041872">
        <property type="entry name" value="Anticodon_Met"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023458">
        <property type="entry name" value="Met-tRNA_ligase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014758">
        <property type="entry name" value="Met-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015413">
        <property type="entry name" value="Methionyl/Leucyl_tRNA_Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033911">
        <property type="entry name" value="MetRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029038">
        <property type="entry name" value="MetRS_Zn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45765">
        <property type="entry name" value="PTHR45765"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19303">
        <property type="entry name" value="Anticodon_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09334">
        <property type="entry name" value="tRNA-synt_1g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01041">
        <property type="entry name" value="TRNASYNTHMET"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57770">
        <property type="entry name" value="SSF57770"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00398">
        <property type="entry name" value="metG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10 11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="7 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 10 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 10 11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNA-synt_1g" evidence="12">
        <location>
            <begin position="5"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_3" evidence="13">
        <location>
            <begin position="423"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="10">
        <location>
            <begin position="12"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU363039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF09334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF19303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KPL76054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="593" mass="67754" checksum="BB388288D8FA9647" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7Y3</accession>
    <name>A0A0P6X7Y3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pyridine nucleotide-disulfide oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_04530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061767.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04530"/>
    <dbReference type="EnsemblBacteria" id="KPL79131">
        <property type="protein sequence ID" value="KPL79131"/>
        <property type="gene ID" value="ADN00_04530"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.264"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="1">
        <location>
            <begin position="7"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="425" mass="46803" checksum="944AD16E79940F5B" modified="2016-01-20" version="1">MAIKDLYDVVVIGSGPGGLAAAISAKKAGADDVLIIERDVELGGILLQCIHNGFGVEIFKEDLPGPGYAQRFINEALSLGVETMLDTMVLDVTPHRKIYVSSKTYGFKVIQARAIVLAMGCRERTRSQIRLPGTRPAGVYTAGTAQRFTNVEGFMPGKKYVILGSGDIGMIMARRLTFEGAKVERVLEIMPFLTGLTRNFVQCLQDYDIPLQLQHTIKRIIGNDRVEAIEAVRVDDKWNMVPGSEEIIPCDTLLLSVGLIPENELSRMAGVQIDPVTGGPYVDETFQTNVPGIFAAGNVVHVYDLVDWVTEAGFAAGDGAGKFAVSQKKKAAQSIGLLAGNNIRYVVPHRIEKESLQDEPIKLQMRVRQPMEEPVWVEVHDGENLITRRGERYVRPGEMVTVTLKPKDFDAIRNTDRLTVQVVTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X843</accession>
    <name>A0A0P6X843_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_06930</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062255.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78213">
        <property type="protein sequence ID" value="KPL78213"/>
        <property type="gene ID" value="ADN00_06930"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036162">
        <property type="entry name" value="Resolvase-like_N_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="135" mass="15205" checksum="59DA6158A1842BE7" modified="2016-01-20" version="1">MFEVLMQANGYRVDYFNPNTRTPNSFAFYVCGELKKGEPYSKQAKRDLFAGLALLANEVGWQNLAAVYLDVSGKRGAERKAFEQMKADARRGMFQRVFVVRLDVLPEDLPDVDVRVLGRGCLSPLDGKRIIPVMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X8S6</accession>
    <name>A0A0P6X8S6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SH3b domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_03170</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000014">
        <property type="protein sequence ID" value="KPL79341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061511.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000014.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03170"/>
    <dbReference type="EnsemblBacteria" id="KPL79341">
        <property type="protein sequence ID" value="KPL79341"/>
        <property type="gene ID" value="ADN00_03170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005240">
        <property type="entry name" value="DUF389"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003646">
        <property type="entry name" value="SH3-like_bac-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04087">
        <property type="entry name" value="DUF389"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08239">
        <property type="entry name" value="SH3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="54"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="77"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="111"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="149"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="179"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="208"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="236"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="SH3b" evidence="3">
        <location>
            <begin position="330"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL79341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="397" mass="41790" checksum="3C7F48CB81AC9BB4" modified="2016-01-20" version="1">MTLPTSEPILSDEPENLPPARRRQQRRTIVPPDRSEQARFLEELAHRVIPSADFFLFTLVCGLISAVALLFDAPALFVLAALVAPFMAPVSGLSLATVFGSARFLLQALGSLLMGGLLVTASGAAAGWLSSLLPRQSHLQALAHTHFTWADLFLLAVGAVLTTLMLARAPKQKPLIPSVALAYELYLPLAAAGFGLTSQQSGFWPDGLIVFAVHLALAALLGALTLALIGLRPRTLFGYTVGSTLVLAGLAAVVVISGFGTALSTQVAMPPPTPTLTPTITLTPSITPTPLPPTATLTPTKTLVPSRTPTLTFTPKPTPIYARIQAVGGDGAIIRQEPSTTSAYIRVVSNGMLVEVLPESTEAGATIWVRVRTTGEDPVEGWILRELLATAAPQPAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X958</accession>
    <name>A0A0P6X958_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rplO</name>
        <name evidence="8" type="ORF">ADN00_12510</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Binds to the 23S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063351.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12510"/>
    <dbReference type="EnsemblBacteria" id="KPL76149">
        <property type="protein sequence ID" value="KPL76149"/>
        <property type="gene ID" value="ADN00_12510"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3983"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01341">
        <property type="entry name" value="Ribosomal_L15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036227">
        <property type="entry name" value="L18e/L15P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030878">
        <property type="entry name" value="Ribosomal_L15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005749">
        <property type="entry name" value="Ribosomal_L15_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021131">
        <property type="entry name" value="Ribosomal_L18e/L15P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12934">
        <property type="entry name" value="PTHR12934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00828">
        <property type="entry name" value="Ribosomal_L27A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52080">
        <property type="entry name" value="SSF52080"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01071">
        <property type="entry name" value="rplO_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L18e/L15P" evidence="7">
        <location>
            <begin position="27"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL76149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="150" mass="15876" checksum="5EA1433142C53CFF" modified="2016-01-20" version="1">MKLNDLKPNEGATKKPKRVGRGHAAGQGKTAGRGTKGLGARNGSGGKLYRQGGNLPFYRRLPFMRGEGFTPINRVEYNEINVEQLARFEAGTVITPELLADAKLISKPKNPVVVLGRGELTVALTVKAQRVSKGAKAVIEAAGGSVEIIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9T5</accession>
    <name>A0A0P6X9T5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HTH luxR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_06240</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062102.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78816">
        <property type="protein sequence ID" value="KPL78816"/>
        <property type="gene ID" value="ADN00_06240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="37"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="64"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="92"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="199"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL78816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="267" mass="28965" checksum="7E03FADD080CF060" modified="2016-01-20" version="1">MSIKLSSDRSQAISLVLMCGGVLLLILNIILGDKVNISLPFVFILLGAAVFVLTFALSKRWRWAFGLFIPGSILVALGVIFLLNVITNDWNSWAYAWLLLLAGGGWGLALAGWYGEWRRDILFIGAMLVVFGFVFYAVFGAIAGGAVIRISAPILLVLGGLALRWLPLEDILPETVSDWLRLSKKEEGGSVMAGGVKTTANLVEPLSTRELEVLALINRGLSNPEIAAELVVAPSTIKTHINNLYGKLGVQNRVQAIQRARELGLLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XA56</accession>
    <name>A0A0P6XA56_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_02305</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000010">
        <property type="protein sequence ID" value="KPL79652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061346.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000010.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02305"/>
    <dbReference type="EnsemblBacteria" id="KPL79652">
        <property type="protein sequence ID" value="KPL79652"/>
        <property type="gene ID" value="ADN00_02305"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="461" mass="51431" checksum="A19ACC95EAEEBDD6" modified="2016-01-20" version="1">MTRKLLFSALTLMLTASLCLVGAGLAVGGLLLLTPAKSSAQISVEPFPVILPDALPDEPLPAGVLEEMNQIQLEVAQLRRLTPRQAVYRDVLSPAELEVVVKEEFFRDYTAEDAQSDAQLLTALGLLPNGFELLDFYEELFSEQVAGYYDSQTGRMVVVQGDDFSGVERMTYAHEYTHALQDQTYDLRNGLGYEDSVCMLEFDACSAVLALIEGDATLSEQLWLFRHATDQDYVDLQDFSLTFETPVYDSAPEFMQQDFMFPYVQGNEFVQTLYDQGGWAAVDQAYANPPVSTEQILHPGLYPAEQPAEVDLPVTADAQNGWKMVDSSVLGEWYTFLLLSYGWQPETRIPLEQARQAAAGWGGDRYRLYANEQTGQTALAVRWQADSAADARELFDALRQYAQQRWTGAETTLPNTERWEVQSDDAAVWLALSGEEVAWLIAPDKTILDGMKGGFSAWQTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAE5</accession>
    <name>A0A0P6XAE5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Peptidase_M50 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_04130</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M50B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061695.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04130"/>
    <dbReference type="EnsemblBacteria" id="KPL79072">
        <property type="protein sequence ID" value="KPL79072"/>
        <property type="gene ID" value="ADN00_04130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044838">
        <property type="entry name" value="EGY1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008915">
        <property type="entry name" value="Peptidase_M50"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31412">
        <property type="entry name" value="PTHR31412"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02163">
        <property type="entry name" value="Peptidase_M50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="88"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="123"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="163"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="191"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="329"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="377"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M50" evidence="8">
        <location>
            <begin position="133"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL79072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="399" mass="44258" checksum="4AB11DE594AB1591" modified="2016-01-20" version="1">MSEDIAYEIFDALVDQVLMVEDRTLGSEKLGYVARYRGRLRSEDSEALYDQLAEGLKAYNITPLFRWDEDRHAVLLVPGRPQASPGRAWVNLVLFIFTLLSVLLTGGMYGFEGDLPANPLEVVWLFLRSGWPFAVSMLAILAAHEFGHYLVGRWHGVNVSLPFFIPMPFSLFGTMGAFINMKSVPKNRKVLLDISVAGPLAGMVVALPVLVLGLRLSTLDALPLTPPQGMVYQIEGNSILYLLLKYLTFGQLLPAPESYGALGPVAHWLRYFFTGRPLPMGGLDVLLHPVAWAGWAGLLVTSLNLIPAGQLDGGHITYVLFGKKAMQRIWPAVLIGLALLGLVWMGWLIWAGLIFFLGRVHAEPLDTITPLDEKRKWLARLALLVFFLTFTPVPLILVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAK8</accession>
    <name>A0A0P6XAK8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_04625</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061786.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79145">
        <property type="protein sequence ID" value="KPL79145"/>
        <property type="gene ID" value="ADN00_04625"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007403">
        <property type="entry name" value="DUF456"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04306">
        <property type="entry name" value="DUF456"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="172" mass="18064" checksum="19CAE31A22D69B97" modified="2016-01-20" version="1">MVDWTSVGTFTLQVITFATMLGGLFSLVVVVIPGLTIIWAAALVYGLVTGFTWQSGVLFAFITILMLVGNVIDNILMGAGARAQGASWLGIGAALVAAVAGSLLVPPFGGLVAALLALFVVEVIRVRDWRKALDSTRSMALGCGWSVAARMGIGGMMIGWWLVWALVLPQIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAN0</accession>
    <name>A0A0P6XAN0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_04880</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061830.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04880"/>
    <dbReference type="EnsemblBacteria" id="KPL79182">
        <property type="protein sequence ID" value="KPL79182"/>
        <property type="gene ID" value="ADN00_04880"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="450" mass="48044" checksum="6121E44D13CC4E1A" modified="2016-01-20" version="1">MKASKSSLSQRIFPLAASLVITSLLLAGCGNLNLPGLLRTVIPPTQTAPNSPLQATVSIPVDETATLPAPTATPSGPQTLTIWVPPQFDPQSGTPAGQQFQARINQFMNENPGVIIETRIKAAAGSGSLLESLTLANAAATPESLPALVALPRSDMEVAALKGLIFPMDDYTSVIDQSDWFDYARQLALLQGATYGIPFAGDAMLLLYRPARVGASPLNWKEILSRGQPLAFPAADPQSLLTLLLYLSAGGQIVDSQGRPTLSAETLTSVLELYAEGAAQGTFPNMIADVQSDAQAWQFYRDKSANMVITWSSRYLSELPVDTSAVAITALDDKDYTLATGWMWALSDPLPERRAMSVKLAEYLTESEYLAQWSPVSGQLPVRPSGLNAITNQSLRSLLGQVIQSSNVRPTNDLITGVGPLLQESTLAMIERLNDPAQAAATVAERLNSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAR4</accession>
    <name>A0A0P6XAR4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_03855</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03855"/>
    <dbReference type="EnsemblBacteria" id="KPL79228">
        <property type="protein sequence ID" value="KPL79228"/>
        <property type="gene ID" value="ADN00_03855"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="293" mass="33008" checksum="0B335525BE87C156" modified="2016-01-20" version="1">MIQNTHYCVEYLKNAGPRIVGFRLRGSDKNLLAETPGEGWKTAHGEYRLYGGHRLWYAPEQPDLTGFPDNDAPLVETLPNGVELVQAVERITGLQRALRVEMEPDGREVKLTHRLENQSPTEMEIAPWAITMLPPGGTVILPQANAPLGNEFLPNRNLVLWPYAHWNDPRVIVKEDHLFVRGEDRGQLLKIGYYNPYGWAAYWHAETLFCKRFAVLPGANYPDRGCNLEVYVNSHYAELESLGPLERVQPGKCVSLAETWEAQPAGRMPEDLEEAWLAAARLCGHLSVEGEGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAZ5</accession>
    <name>A0A0P6XAZ5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_02065</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000008">
        <property type="protein sequence ID" value="KPL79926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061304.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000008.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79926">
        <property type="protein sequence ID" value="KPL79926"/>
        <property type="gene ID" value="ADN00_02065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="85"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="144"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="175"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="237"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="278"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="319"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="357" mass="38126" checksum="E73EBF5BD2C4BE2B" modified="2016-01-20" version="1">MDFGEVLTKAWKTIWKHKILWLFGLLAGCGANGGGGGGGGGGNAGSSFQNGNNGNNFNFDLPRNAPPWLQDFANQLERSFETGTFWAVFGGLMLGLICLAFFLGLVMLFLRTVGKIGLVRGAWQADEGAEKLSLGGLLKETWPYFWRVLLFEVILFVLGVMMTVILIVPVMAVTLLTLGCGLICLLPFLIVLGWAISTLTEMIVVALVGENLDLGAAVQRAWTLLKENLGSLAIMSLILYIGQAIVGFVVALPFFLIAVPLIMAAVAESEAALITGGIVALIIFLVYLPIAILLGAVLQSYVGAAWTLTFRRLTGRQTGDTGAGQIVPKPEPEPLNLEPIEGFMPGEEAQGEEPTEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBW6</accession>
    <name>A0A0P6XBW6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_15790</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063994.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72275">
        <property type="protein sequence ID" value="KPL72275"/>
        <property type="gene ID" value="ADN00_15790"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="148" mass="16638" checksum="2E2B4003472335A3" modified="2016-01-20" version="1">MHELYDVGYQSIKNSGVLIQLAEKMGAVVYDIRFSPKSSDPQWAGINLEITLGGRYIHLKELGNKNYKGGPIELVDQSAGLEAVYSELQNRPVILMCGCWDREKCHRKTAARLFELRYGVVSIPLTSPKIKEILGMVDPPEIKQDSLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBX3</accession>
    <name>A0A0P6XBX3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GAF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_15840</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064004.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15840"/>
    <dbReference type="EnsemblBacteria" id="KPL72284">
        <property type="protein sequence ID" value="KPL72284"/>
        <property type="gene ID" value="ADN00_15840"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="GAF" evidence="2">
        <location>
            <begin position="245"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL72284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="558" mass="61669" checksum="14600BD4C25AEBA2" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBZ3</accession>
    <name>A0A0P6XBZ3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATPase AAA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062711.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09275"/>
    <dbReference type="EnsemblBacteria" id="KPL77310">
        <property type="protein sequence ID" value="KPL77310"/>
        <property type="gene ID" value="ADN00_09275"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4089"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028350">
        <property type="entry name" value="DNAC/ATP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002611">
        <property type="entry name" value="IstB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01695">
        <property type="entry name" value="IstB_IS21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003073">
        <property type="entry name" value="DNAC_TnpB_IstB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="96"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="261" mass="30006" checksum="A31D26612156D0A4" modified="2016-01-20" version="1">MMELDRLLEKLRMDHLEAQIDAVCEQAAKAQLDYKAFLAQALETEWQGRYQRGIEARLRQARFPWLKTLDQFDFDFQPSLDRRQLRELAGMSFVERAHNVIILGPPGVGKTHLAIGLGVKAVEAGYSVLFLTLEELMVRLAKAFHENRLERSLQQLVYPKVLIIDEIGYLPLSNLEASLFFRLVVRRYERASLIITSNKSFLDWGEIFNDPVLATAILDRLLHYSTTLNIKGESYRLKEKRKAGLLGRTNLIASEEQEVTT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XC14</accession>
    <name>A0A0P6XC14_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Heavy metal transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_02195</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000009">
        <property type="protein sequence ID" value="KPL79795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061326.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000009.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02195"/>
    <dbReference type="EnsemblBacteria" id="KPL79795">
        <property type="protein sequence ID" value="KPL79795"/>
        <property type="gene ID" value="ADN00_02195"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006825">
        <property type="term" value="P:copper ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000428">
        <property type="entry name" value="Cu-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017969">
        <property type="entry name" value="Heavy-metal-associated_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00944">
        <property type="entry name" value="CUEXPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="SSF55008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01047">
        <property type="entry name" value="HMA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HMA" evidence="2">
        <location>
            <begin position="3"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="68" mass="7488" checksum="C85593BD6E0024A9" modified="2016-01-20" version="1">MNTITLHIPGISCHHCIHTINTELADMEGVKSVEASLDSKLVTVTFEPPASEDRIRDLLVEINYPAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XCY9</accession>
    <name>A0A0P6XCY9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Glucose-1-phosphate adenylyltransferase</fullName>
            <ecNumber evidence="7">2.7.7.27</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">glgC</name>
        <name evidence="7" type="ORF">ADN00_01635</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.27" evidence="7"/>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061218.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01635"/>
    <dbReference type="EnsemblBacteria" id="KPL80572">
        <property type="protein sequence ID" value="KPL80572"/>
        <property type="gene ID" value="ADN00_01635"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1087"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008878">
        <property type="term" value="F:glucose-1-phosphate adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011831">
        <property type="entry name" value="ADP-Glc_PPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005836">
        <property type="entry name" value="ADP_Glu_pyroP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43523">
        <property type="entry name" value="PTHR43523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02091">
        <property type="entry name" value="glgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00808">
        <property type="entry name" value="ADP_GLC_PYROPHOSPH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00809">
        <property type="entry name" value="ADP_GLC_PYROPHOSPH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2" id="KW-0321">Glycogen metabolism</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="6">
        <location>
            <begin position="9"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL80572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="422" mass="47514" checksum="22832B845F717197" modified="2016-01-20" version="1">MPQSTKVLAVILGGGRGSRLYPLTKNRSKPAVPIGGKYRLIDIPISNCINSGIYKVAILTQFNSVSLHRHIVHTYNFDVFHTGWVQIWAAEQTMQNAGWYQGTADAVRKQIFEILSSHTENVLILAGDHLYRMDYAAMYDFHEKNNADITIAVQPIRKDDAGRFGILKRDPDYHITRFAEKPKDPDVLADLVSRDDPERPFLGSMGIYLFKTDVLVKLLQKYSHLDDFGGDIIPLAIKTHTVFGYDFDGYWEDIGTIRSFYDTNLRMCDPNPPFNFFDPVNPIYTHARFLPGSNIQNTRLDKAFVSEGCCIESAEVIHSVIGLRSQIRKGSVLRDTIMMGADYYGDSAEDYRESTLPLGIGENCQISGAILDKNVRIGNNVVIEPFTDVEDLDDELYVVRDGIVVIPKNTEIPEGTRISPQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XD20</accession>
    <name>A0A0P6XD20_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTAD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_08605</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000022">
        <property type="protein sequence ID" value="KPL77648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062587.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000022.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08605"/>
    <dbReference type="EnsemblBacteria" id="KPL77648">
        <property type="protein sequence ID" value="KPL77648"/>
        <property type="gene ID" value="ADN00_08605"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03704">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01043">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTAD" evidence="1">
        <location>
            <begin position="99"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="1171" mass="133056" checksum="8397D3B00138E1EE" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XD46</accession>
    <name>A0A0P6XD46_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_08810</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000022">
        <property type="protein sequence ID" value="KPL77676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77676">
        <property type="protein sequence ID" value="KPL77676"/>
        <property type="gene ID" value="ADN00_08810"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1483"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL77676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="223" mass="24243" checksum="BD3FE4C0B1E4078B" modified="2016-01-20" version="1">MPPPDSGLPTVSLDAGSLASGYQAETVPAAFGGDLPYWEVLPEYTRVTLQGYAISDHLHEPAIYIYPVRELEKVNEGARTVVSSLQSLLQSPQEIPNMPFLPLFNAGQMMHTHLQYLDFQSGQGLRYLTMFSQGIVPINNDELIYTYQGLTSDGKYYVAAVLPVTHTSLPADGSVTGSEPPEFVSDYAAYVANTAASLNTQAANTFTPDLTQLDAMMSSLEIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XD56</accession>
    <name>A0A0P6XD56_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="3">PPIase</shortName>
            <ecNumber evidence="3">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_08665</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 3">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="3"/>
    <dbReference type="EMBL" id="LGCL01000022">
        <property type="protein sequence ID" value="KPL77685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08665"/>
    <dbReference type="EnsemblBacteria" id="KPL77685">
        <property type="protein sequence ID" value="KPL77685"/>
        <property type="gene ID" value="ADN00_08665"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1448"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000413">
        <property type="term" value="P:protein peptidyl-prolyl isomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024936">
        <property type="entry name" value="Cyclophilin-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PTHR45625"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001467">
        <property type="entry name" value="Peptidylpro_ismrse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="SSF50891"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="4">
        <location>
            <begin position="25"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL77685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="167" mass="17872" checksum="D6DF4B929BC3AE8D" modified="2016-01-20" version="1">MYDACPPTVIDPTKKYTATIETTKGNFVMDLYADKAPVTVNSFVFLANEGWFNDIPFHRVIDGFVAQTGDPSGLGLGGPGYQYSNEISDLGFDKAGVVGMANAGPESNGSQFFITLAPVEQLSGNYTVFGQVTEGMDVVSSLNKIDPSANESVENADRIIKVTISEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDA1</accession>
    <name>A0A0P6XDA1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_07060</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062280.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07060"/>
    <dbReference type="EnsemblBacteria" id="KPL78230">
        <property type="protein sequence ID" value="KPL78230"/>
        <property type="gene ID" value="ADN00_07060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032688">
        <property type="entry name" value="ABC2_membrane_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002798">
        <property type="entry name" value="SpoIIM-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12679">
        <property type="entry name" value="ABC2_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01944">
        <property type="entry name" value="SpoIIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="66"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="149"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="213"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="285"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="326"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="351"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="393"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="442"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL78230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="473" mass="52369" checksum="16B17ABD6A737F02" modified="2016-01-20" version="1">MQELLQKIRPALVITRREVRDQLRDWRIILPVLFLTVFFPFLMNFTAQQMLDFVSQYGASVIGERLVPFLLMIVGFFPISVSLVIALETFVGEKERGSIEPLLNTPLEDWQLYLGKLLSSVVPPLTASFLGMAVYLIGLASKGVPLPELPMLIQIFALTTVQAVVMVSGAVVVSSQATSVRATNLLASFIVIPVAFLIQGESVVMFWGDYTALWWVVGGLVILTFLLMRVGLAHFQREELLGREIDVLNVKWMWRTFWNAFGGNARTVWEWFGRVIPESLRELRFSMLAMLVIGAAGVWVGARMVNTFYISLGGETFTDLPDRMELLTEIFPLFGFGPVMGIWWQNVRVMILAMLLGVFSVGILGTLPLLASLGVAGYLGALLTMNGLPLETYLMFLIPHGVLEIPAVIIGSAAVLQMGILQATPNAEKTVGEVWLISLARWLRVMVGVVAPLLLIAAAVESWVTPQILKAFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDS7</accession>
    <name>A0A0P6XDS7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SH3b domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_00545</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061003.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00545"/>
    <dbReference type="EnsemblBacteria" id="KPL81056">
        <property type="protein sequence ID" value="KPL81056"/>
        <property type="gene ID" value="ADN00_00545"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003646">
        <property type="entry name" value="SH3-like_bac-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08239">
        <property type="entry name" value="SH3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51781">
        <property type="entry name" value="SH3B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="186"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="SH3b" evidence="2">
        <location>
            <begin position="52"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL81056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="209" mass="21902" checksum="7CE29F5E5E2572AC" modified="2016-01-20" version="1">MKFRTIMLSVSILLVLVIFSISGLFDVQAGTLNQMPTVDIATVTGTPTGVIATVKMDVDQGQVNVRNGPGTFYDKVGVLLAGQKVPAKGKSVAGEWIMIEYPGVQGGIAWIYSPLVDLSPGNLAIVEPPPTPTPLVTPTIDPTLAAQFVITNVPTRLPSYTPPPPLAIPTFNENIQGIALSSRMPVGLLIIGLAGAGILIGIFTFAQRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDT9</accession>
    <name>A0A0P6XDT9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HAD family hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_08400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062538.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08400"/>
    <dbReference type="EnsemblBacteria" id="KPL77886">
        <property type="protein sequence ID" value="KPL77886"/>
        <property type="gene ID" value="ADN00_08400"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.682"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006675">
        <property type="entry name" value="HDIG_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00277">
        <property type="entry name" value="HDIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD" evidence="1">
        <location>
            <begin position="26"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="198" mass="22134" checksum="FB559A19E0079BB0" modified="2016-01-20" version="1">MQPNPVYTRDAALQIVQEYIQSHNLINHMLSVEAAMRFYARYFHEDEDLWGITGLLHDFDWEKYPTLDQHGVAGAPILRERGVPEVIVQAILSHVDSSGVARETTLQKALFACDEITGLITAVALVRPSRSLMDLTSKSVKKKWKDKAFAAGANRDEIEHATQELGIDLWQHVDNVILAMREIASQLGLAGETTPSVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XFC2</accession>
    <name>A0A0P6XFC2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase</fullName>
            <ecNumber evidence="6 7">6.3.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">D-alanyl-D-alanine-adding enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">murF</name>
        <name evidence="11" type="ORF">ADN00_07365</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>ATP + D-alanyl-D-alanine + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminoheptanedioate = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine</text>
            <dbReference type="Rhea" id="RHEA:28374"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57822"/>
            <dbReference type="ChEBI" id="CHEBI:61386"/>
            <dbReference type="ChEBI" id="CHEBI:83905"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6 7">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the MurCDEF family. MurF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.10" evidence="6 7"/>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07365"/>
    <dbReference type="EnsemblBacteria" id="KPL78352">
        <property type="protein sequence ID" value="KPL78352"/>
        <property type="gene ID" value="ADN00_07365"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3295"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047480">
        <property type="term" value="F:UDP-N-acetylmuramoyl-tripeptide-D-alanyl-D-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008766">
        <property type="term" value="F:UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02019">
        <property type="entry name" value="MurF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000713">
        <property type="entry name" value="Mur_ligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035911">
        <property type="entry name" value="MurE/MurF_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005863">
        <property type="entry name" value="UDP-N-AcMur_synth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01225">
        <property type="entry name" value="Mur_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63418">
        <property type="entry name" value="SSF63418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01143">
        <property type="entry name" value="murF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6 7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1 6 7" id="KW-0132">Cell division</keyword>
    <keyword evidence="2 6 7" id="KW-0133">Cell shape</keyword>
    <keyword evidence="5 6 7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 6 7" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase" evidence="8">
        <location>
            <begin position="21"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_M" evidence="10">
        <location>
            <begin position="117"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="9">
        <location>
            <begin position="328"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL78352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="466" mass="50396" checksum="53AB554113B9278E" modified="2016-01-20" version="1">MEALSGVRPPNAPLMISEAAVDSRQVIPAGLFVALPGERVDGHDYVEEAFRKGASVALVQKDLSIPYPTITLTPGQFSAQNTMPRAPFCIRVENTLTALQKIAQFWRSKLDLRVIGITGSVGKSTTKELVAGVLSQRYRTLKNIGNLNNEIGLPLTILRLGPGHQRAVLEMGFYVPGEIALLCEIARPHVGIVTNIGAVHAERAGSIEAIARGKSELVQALPPAPAGTAILNYDDDLVRPMANLTHANIFFYGLDPKADLWADQIESLGLEGIRFRLHYRKESIQLRAPLIGQHSVHTALRAAAVGLVEGLKWQEIVTGLQKGHTQLRLVTVRAQNGALLLDDTYNASPESTLAALNLLGELEGRKIAVLGDMLELGQYEEKGHHMVGVRAAEVCAELIAVGERSQMIVDGAKSAGMRPSRISWVSDVPEAIELLKKKLKANDVVLLKGSHGLHMERITAALEADS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XFI6</accession>
    <name>A0A0P6XFI6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_03445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061568.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03445"/>
    <dbReference type="EnsemblBacteria" id="KPL78961">
        <property type="protein sequence ID" value="KPL78961"/>
        <property type="gene ID" value="ADN00_03445"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005746">
        <property type="entry name" value="Thioredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01068">
        <property type="entry name" value="thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="1">
        <location>
            <begin position="1"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="278" mass="31254" checksum="29F4D6E5C02E12C1" modified="2016-01-20" version="1">MGNADFILDVNETNFEFEVISYSQNTPVVVDFWAEWCRPCKALGPILEKLAIEMNGAFRLARLDVDHNPNLAILYNVRSIPTVKAFSQGEIVSEFVGLLPENRIREFLEAITPPSTLNLTLEKANSLLAQHDWQAAAELFQEILEQDPDQPAALLGLAKCLLAIGRHQDALVILTSFPTSKEFKQSELLLPYARALADFHGNQLPDENELDAAFRNSIRLAQRGNILAALDGLLDILRQNRHYRGDKARLVFLSLLELLGDEDPQTRQYRAELASTLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XFJ6</accession>
    <name>A0A0P6XFJ6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_06785</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000018">
        <property type="protein sequence ID" value="KPL78425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062225.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000018.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06785"/>
    <dbReference type="EnsemblBacteria" id="KPL78425">
        <property type="protein sequence ID" value="KPL78425"/>
        <property type="gene ID" value="ADN00_06785"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010390">
        <property type="entry name" value="DUF990"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06182">
        <property type="entry name" value="ABC2_membrane_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="231"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="263" mass="28946" checksum="7EF7E1F470A8A7D4" modified="2016-01-20" version="1">MYWMKLIGALMRASAQEELAYRENFWMQVLHSLLNLGVGVLGMSVLFAQVRQISGWDYASALAILGVYLVVSALRGLFIGPSLEALAGLGQEIWNGQFDFTLLRPANTRFLVTFRRWRFFALFDLLLGVGVLAAAVTRAQQPIGLENWLLFGLALLAAVVLLYAALLAFTSLAFQSPGMVFTWVFDAVFQLARYPVQIYPPALRFALTWLVPVGMMTSIPAQALTGQLNPWMLAGGLALAAVMLVGASWVFDRATRRYASASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XFW8</accession>
    <name>A0A0P6XFW8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_13975</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063646.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000033.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74109">
        <property type="protein sequence ID" value="KPL74109"/>
        <property type="gene ID" value="ADN00_13975"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL74109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="724" mass="77883" checksum="3929BB2ADE9E9627" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGF8</accession>
    <name>A0A0P6XGF8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 10 11">Ribulose-phosphate 3-epimerase</fullName>
            <ecNumber evidence="7 10 11">5.1.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">rpe</name>
        <name evidence="15" type="ORF">ADN00_13755</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the reversible epimerization of D-ribulose 5-phosphate to D-xylulose 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10 11">
            <text>D-ribulose 5-phosphate = D-xylulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:13677"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="EC" id="5.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10 13">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="10 13">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Carbohydrate degradation.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 10 11">Belongs to the ribulose-phosphate 3-epimerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.1" evidence="7 10 11"/>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063599.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000032.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13755"/>
    <dbReference type="EnsemblBacteria" id="KPL74356">
        <property type="protein sequence ID" value="KPL74356"/>
        <property type="gene ID" value="ADN00_13755"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1328"/>
    <dbReference type="UniPathway" id="UPA00232"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004750">
        <property type="term" value="F:D-ribulose-phosphate 3-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019323">
        <property type="term" value="P:pentose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00429">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02227">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026019">
        <property type="entry name" value="Ribul_P_3_epim"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000056">
        <property type="entry name" value="Ribul_P_3_epim-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11749">
        <property type="entry name" value="PTHR11749"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00834">
        <property type="entry name" value="Ribul_P_3_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001461">
        <property type="entry name" value="RPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01163">
        <property type="entry name" value="rpe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01085">
        <property type="entry name" value="RIBUL_P_3_EPIMER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01086">
        <property type="entry name" value="RIBUL_P_3_EPIMER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="13" id="KW-0170">Cobalt</keyword>
    <keyword evidence="9 10 11" id="KW-0413">Isomerase</keyword>
    <keyword evidence="13" id="KW-0464">Manganese</keyword>
    <keyword evidence="8 10 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="10 14">
        <location>
            <begin position="143"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="176"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="14">
        <location>
            <begin position="198"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10 12">
        <location>
            <position position="36"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="10 12">
        <location>
            <position position="176"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10 14">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 13 14">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10 13">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="178"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00001954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00009541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR001461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR001461-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KPL74356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="220" mass="23700" checksum="C4DF72891101525D" modified="2016-01-20" version="1">MNNIILSASILSADFARLGEELRAASATDLDWVHIDVMDGQFVPNISMGPFIVETCNRITDLPLDVHLMIQQPERHIQSFAKAGADWISVHYEGNPNIHRTLQEIRALGCHPGIVINPGTPAAVLESVLDMVDLVLVMSVNPGFSGQKFMPEMARKIAQVDSMLKQINSSAIIQVDGGITSETICAAYDAGARSFVAATAIFKHPQGIAAGIASLRNAVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XHC0</accession>
    <name>A0A0P6XHC0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_05000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05000"/>
    <dbReference type="EnsemblBacteria" id="KPL79203">
        <property type="protein sequence ID" value="KPL79203"/>
        <property type="gene ID" value="ADN00_05000"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005079">
        <property type="entry name" value="Peptidase_C45"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03417">
        <property type="entry name" value="AAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="326" mass="35565" checksum="5DBD3BD7CC6DF8CC" modified="2016-01-20" version="1">MVMAGVIAACVWAFQPLATLLSLRKLNDYPLYRLDYYGDMQSNLAKAEALEHFFASWEQAIASQPQAGFACSLFFSAADPADMQYGRNFDWQYSPALVVVVHQPGGSTSISIANPQWMGFSVQRAAHLDQLPLVERLPLLASPALLTDGMNNRGLVVGMAAVPERGELFDAQKPTLDSLMAMRALLDTTASVPEAVELLAAHNIDMGSGPSIHYLIADSSGQSALVEITADGFFQSAPNGPYQTATNHYFTDPPEQQPACPRLETMNQALQAAGGRLAPGEAMRLLQQVSQANTQWSVVYHNTSGLMEVVMDLRYDQPLTLRLNMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XIG6</accession>
    <name>A0A0P6XIG6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_17950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000043">
        <property type="protein sequence ID" value="KPL70913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064417.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000043.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17950"/>
    <dbReference type="EnsemblBacteria" id="KPL70913">
        <property type="protein sequence ID" value="KPL70913"/>
        <property type="gene ID" value="ADN00_17950"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="195"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="227"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="262"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="291" mass="31327" checksum="1FDC8EFD70F1FB22" modified="2016-01-20" version="1">MKTSSRTLTILSVLAGLLGLAAALAGLFWPAEGSPFTVTSVHGTQVELWGQGLYRFDAYFRAPIFRGGDAVTAFIAFPLLVFAIIANAKGSRRGRLLLAGTLTYFLYNMASLALGTAYNPMLLVYILGFSASFFALIEAIASLDKPALAAHVTSRMPHKAIAIFMFIAGLSVFVWLLDVINFLTTGQFPETLATYTTEITTVLDIGLITPVAYLAGIRLLQRRPIGYVLAAIMLLMNIFIGLVVISQTIFQSAAGISLPPQVMVIFVGTFVVTSVAAIVLAVLFFRSVEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XIM8</accession>
    <name>A0A0P6XIM8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_13435</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063535.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000031.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13435"/>
    <dbReference type="EnsemblBacteria" id="KPL74835">
        <property type="protein sequence ID" value="KPL74835"/>
        <property type="gene ID" value="ADN00_13435"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL74835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="213" mass="23758" checksum="206F48C01CCCB32C" modified="2016-01-20" version="1">METITELRPVVFAGLPLFNMMPILQTNTRKILRIGISGHRFLSDPERLTAALENVCQTLHFRFPQIGWQICSPLAEGADRLAASVFLKHQSDLIAILPLPPEEYLLSFSTADSREEFTQYLYKAQEVIQLPAQPDVDQAYAALGLFLLENCDILLVIWDGSASQGKGGTGEIALEARRRKIPMIWIHAGNRISGTQTATSLGDEQGRVDYENF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XIU0</accession>
    <name>A0A0P6XIU0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01955</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000007">
        <property type="protein sequence ID" value="KPL80059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80059">
        <property type="protein sequence ID" value="KPL80059"/>
        <property type="gene ID" value="ADN00_01955"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133078" evidence="1">
        <location>
            <begin position="27"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="144" mass="15488" checksum="716F64E8BE0818DA" modified="2016-01-20" version="1">MNSLKRIFLWLILWVSLVGLACSASGAGTDNARYAPAGDGTEYPQEPEEVVSAFLAAQQEDPKQMERYLSTTALAQLPPEGAVEMLHCQDVVMGYLISSASVSQNPPGAIVEVNLTTGQAELGRAFVLLRQNGVWVIDEILALP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XJA0</accession>
    <name>A0A0P6XJA0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01880</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000007">
        <property type="protein sequence ID" value="KPL80044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061267.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000007.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01880"/>
    <dbReference type="EnsemblBacteria" id="KPL80044">
        <property type="protein sequence ID" value="KPL80044"/>
        <property type="gene ID" value="ADN00_01880"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2302"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006474">
        <property type="term" value="P:N-terminal protein amino acid acetylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006464">
        <property type="entry name" value="AcTrfase_RimI/Ard1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01575">
        <property type="entry name" value="rimI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="6"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="166" mass="18710" checksum="9DB72C465EA7B0FE" modified="2016-01-20" version="1">MEESQLLIRRMQEADIPQVHEIDTLSLSLPWSERSYRFEVCENRAARPWVAEATLPDGSRKLAAMLVLWLILDEAHIATVAVHPDYRRKGIGLRLTAHALADAAQNGAKTAYLEVRAGNFSAQELYQKLGFRVEGVRPRYYRDNHEDALLMALENLNAEALQALAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XJM2</accession>
    <name>A0A0P6XJM2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">Flagellar biosynthetic protein FliP</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">fliP</name>
        <name evidence="13" type="ORF">ADN00_17200</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Plays a role in the flagellum-specific transport system.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cell membrane</location>
            <topology evidence="12">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="12">Bacterial flagellum basal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the FliP/MopC/SpaP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17200"/>
    <dbReference type="EnsemblBacteria" id="KPL71489">
        <property type="protein sequence ID" value="KPL71489"/>
        <property type="gene ID" value="ADN00_17200"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.502"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044781">
        <property type="term" value="P:bacterial-type flagellum organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005837">
        <property type="entry name" value="FliP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005838">
        <property type="entry name" value="T3SS_IM_P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30587">
        <property type="entry name" value="PTHR30587"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30587:SF0">
        <property type="entry name" value="PTHR30587:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00813">
        <property type="entry name" value="FliP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00951">
        <property type="entry name" value="FLGBIOSNFLIP"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01302">
        <property type="entry name" value="TYPE3IMPPROT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01103">
        <property type="entry name" value="fliP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01061">
        <property type="entry name" value="FLIP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="7 12" id="KW-1005">Bacterial flagellum biogenesis</keyword>
    <keyword evidence="11 12" id="KW-1006">Bacterial flagellum protein export</keyword>
    <keyword evidence="5 12" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="13" id="KW-0966">Cell projection</keyword>
    <keyword evidence="13" id="KW-0969">Cilium</keyword>
    <keyword evidence="13" id="KW-0282">Flagellum</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="25"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="69"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="168"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU362069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KPL71489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="225" mass="24787" checksum="2ACA6BBB66A21851" modified="2016-01-20" version="1">MTAPGVTLTVDPAGEPEKVAQGVQLLVLLTVLTIAPSILILATSFTRIVIVLSMVRNAIGTPTIPPNQVVIGLSLVLTFFIMTPTYDKINQNALQPYLDSQITQEEALKRAADPLREFMFKQTREKDIALFLQMGGQPQPQTLADIPTVSLFPAFVISELRTAFTMGFIIYIPFLIIDLVISSVLLSMGMMMLPPSLIALPFKLMLFVLVDGWFLITRSLALSFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XJV7</accession>
    <name>A0A0P6XJV7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_12335</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063317.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76120">
        <property type="protein sequence ID" value="KPL76120"/>
        <property type="gene ID" value="ADN00_12335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="180" mass="19297" checksum="D60064D7ED6729AC" modified="2016-01-20" version="1">MTDNDKSCLAAALFIFALFFPLVALAIGWIGWDFKTGAYAALVTFGVLAIPAAILFLTVRDPSAWVSSLPLLLGTLYTILPDAILGGVDDGAVFSLGALLSFLLWRRKDASLPTWLLIPIVISAAYTFLGGFIPGPFDEILVYLVSAVVSWIKMSQPGSSAPSSAADIIEAEWRDLTQNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKU3</accession>
    <name>A0A0P6XKU3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_15535</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063945.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72230">
        <property type="protein sequence ID" value="KPL72230"/>
        <property type="gene ID" value="ADN00_15535"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="258"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="290" mass="32025" checksum="E552FF0CA951D6CB" modified="2016-01-20" version="1">MITLPDDVSASLNTGMQVGSAIELPFFTPTFWFLNGDARLLQVGGASYFGGWAVSKEHWDRATKEEWFTDPSENAGLVETNLVTSDNKPLETCTSRSLIVAPMCSRLTWTTQDGGRYIEYVPGGRQHLQVIALLASRHEDGSFNALGPVMLTAKGFQAKNLQDSFAAWDRATKSIRQKVAPNVPAWCFYAAVGTFGTERKQVMVGKTSQKAITPVSCYIPKQITEDTITKLFVGQDNAASMAVYIEAAQEWLHAYDARKAQPQPSQTQAVPQPPTYDELPPFDDHEPLPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XL91</accession>
    <name>A0A0P6XL91_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_00490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL81049">
        <property type="protein sequence ID" value="KPL81049"/>
        <property type="gene ID" value="ADN00_00490"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036278">
        <property type="entry name" value="Sialidase_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50939">
        <property type="entry name" value="SSF50939"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="807"/>
            <end position="827"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL81049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="834" mass="93281" checksum="1542E647E67AAC37" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XLR6</accession>
    <name>A0A0P6XLR6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_12250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063303.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12250"/>
    <dbReference type="EnsemblBacteria" id="KPL76105">
        <property type="protein sequence ID" value="KPL76105"/>
        <property type="gene ID" value="ADN00_12250"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003797">
        <property type="entry name" value="DegV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043168">
        <property type="entry name" value="DegV_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02645">
        <property type="entry name" value="DegV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00762">
        <property type="entry name" value="DegV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51482">
        <property type="entry name" value="DEGV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="287" mass="31497" checksum="479CB981E031686E" modified="2016-01-20" version="1">MRIVTDRGADLADEQLKDLEVDFLPLMIYFEGNIYKGGEDLTAVEFYQMLEKSEAFPSTSQPSPGDFAKIYRKLADMGEEIFSLHISSGLSGTMNAAMEGAKLVPEAKVTFYDSKTLSVPLGWQVEAAAKMFKAGWPLEKVIKKLDEISEKANGFYTLSDLKYLVHGGRISHLKGLIASLLKIKPVIGVDKITGKYETFGQEITLKRAVGKMLDVIEEMYGASTELRVQLLNGHNPEGLAYLKEKISQRFKCKFEPSVAIAPVLGAHTGPSMIGLSVAPLAVFADLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQ45</accession>
    <name>A0A0P6XQ45_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Amino acid ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_09425</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09425"/>
    <dbReference type="EnsemblBacteria" id="KPL77367">
        <property type="protein sequence ID" value="KPL77367"/>
        <property type="gene ID" value="ADN00_09425"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010065">
        <property type="entry name" value="AA_ABC_transptr_permease_3TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043429">
        <property type="entry name" value="ArtM/GltK/GlnP/TcyL/YhdX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30614">
        <property type="entry name" value="PTHR30614"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01726">
        <property type="entry name" value="HEQRo_perm_3TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="245"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="7">
        <location>
            <begin position="48"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL77367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="276" mass="30884" checksum="F85E001F94192342" modified="2016-01-20" version="1">MQKEQRKFNYRDFPWWFPAMVLIAIITTYTIITRENYTEAFNFIKVGLGVTVQTTFWAFLLALLFGLLAGLARISHNVVLKNLATLYVELVRGIPMLVLIFFIALVGVPALVNGMNALGNWITSIGLQAVATPFLLVQNKDVSMNLRAIIALSVTYGAFLAEIFRAGIQSIGKGQMEAARSQGMSYPQAMRFVILPQAIRNVLPALGNDFVSMLKDSSLVSVLAVRDITQVARLYAGHSFRYQEAYITLAVMYLTMTVALSLLVKLIERRIRKDEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQ55</accession>
    <name>A0A0P6XQ55_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">UDP-N-acetylglucosamine 2-epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_05585</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UDP-N-acetylglucosamine 2-epimerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05585"/>
    <dbReference type="EnsemblBacteria" id="KPL78872">
        <property type="protein sequence ID" value="KPL78872"/>
        <property type="gene ID" value="ADN00_05585"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1594"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008761">
        <property type="term" value="F:UDP-N-acetylglucosamine 2-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003331">
        <property type="entry name" value="UDP_GlcNAc_Epimerase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029767">
        <property type="entry name" value="WecB-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43174">
        <property type="entry name" value="PTHR43174"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02350">
        <property type="entry name" value="Epimerase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00236">
        <property type="entry name" value="wecB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase_2" evidence="2">
        <location>
            <begin position="22"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="373" mass="41195" checksum="55786AF789DCB8B4" modified="2016-01-20" version="1">MIKVLSIFGTRPEAVKMAPVVKQLEAHPEIESRVCVTAQHRQMLDQVLDLFAIQPDIDLNLMRENQSLAGLTSEILIHLEPVLKDLKPDWVLVQGDTTTVMTAALLCYYNRIKVGHVEAGLRTGDKWQPFPEEVNRRIASVVTDLHFAPTEHSRQNLLREGVADELIVVTGNPVIDALQEITRRPAPQMVASLLADKGIGAGGKQLILVTAHRRENFGQPIRDICAALKTLANRYRGQVELVYPVHLNPNIKDVVSRELGAVENITLLPPLDYLPLVHLMKQSKLVLTDSGGIQEEATSMGIPTLVLREVTERPEGVDAGVLRLVGTDPDRIVSETRRLLEDEAAYTAMSQAKNPFGDGRAAEKIVQAIVKRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XR22</accession>
    <name>A0A0P6XR22_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_16145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064074.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72021">
        <property type="protein sequence ID" value="KPL72021"/>
        <property type="gene ID" value="ADN00_16145"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3664"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05257">
        <property type="entry name" value="Arna_like_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045869">
        <property type="entry name" value="Arna-like_SDR_e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="17"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="337" mass="37356" checksum="2111AC7EBCE8B6B9" modified="2016-01-20" version="1">MQVSSEEQQFFEGKKILVTGGGGFIGSHLIETLVKAGAQVRAFVRYNSRADPGLLAFLPQQTSKEVEILSGDLRDYDAVRQAMRGVSILFHLGALISIPYSYLHPVEVVETNVMGALNILMAARENGIERIVHTSSSEVYGTAITVPIAESHPLQGQSPYSASKIGADKLAESFYCAYQVPVVILRPFNTYGPRQSARAVIPTIICQALTRDYLQLGNLEARRDFTYVSDTVSGFLRAASIPGIEGQTFNLGVGSDVSIGNLAREIIQLIGRPVEIRLDQQRLRPEKSEVMRLISDNRLARERMGWSPVVDLQTGLQHTIGWIEQHLNRYRPDLYQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XR86</accession>
    <name>A0A0P6XR86_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_03040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000014">
        <property type="protein sequence ID" value="KPL79320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79320">
        <property type="protein sequence ID" value="KPL79320"/>
        <property type="gene ID" value="ADN00_03040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="466" mass="50285" checksum="D030D55BA0254661" modified="2016-01-20" version="1">MDEKMEMLTMKHNRLMISLALTSLVLAALACNVPGHMPPTAAPTLSDAAVATQVAKTMQAVGDVAAPTATPELVVTATSEPAAPALEGLRVAYSDANRDLWVWDEGEPPVKVLDTGDVVDVKLSPDGAQLLFARSLDYAAYSLWVMGADGGSPQELVSADEFEDMKAYENAITAQPFVYDWVPGKKQAYFVTSPVFEGPGLVVNDDLWMVDTETGDFRALLAAGEGGLPYFSPDGEKVMLATSENILMMNADGSGLSVVKEFEPVLTYSEYMYYPSVQWRSDSELAAAAIPPKDSLAEDPQDTWTGFLTLAGEAQEIKSVPAYFLSAAVFNQQLNAFAYLKNAGAQGENRRELRLATSLAPGSMADAVFATGNLEFIAWAPDGVRFAYRDNGEDKTMLGQVGAGRMQLAGVDDPIGFAWIDDSSFLYLQRTDESWKMFTTRIGSDPVEVADLGPVDASFPTYSFVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XS38</accession>
    <name>A0A0P6XS38_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PLD phosphodiesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000028">
        <property type="protein sequence ID" value="KPL75311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063464.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000028.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13055"/>
    <dbReference type="EnsemblBacteria" id="KPL75311">
        <property type="protein sequence ID" value="KPL75311"/>
        <property type="gene ID" value="ADN00_13055"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PLD phosphodiesterase" evidence="1">
        <location>
            <begin position="87"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL75311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="344" mass="39211" checksum="ADD72BA703731D25" modified="2016-01-20" version="1">MPELIIPNWSALSEVIQVAEERILICSPYYSDRSINFLVDNLGDVPVLQFWTRLNPQDWLSGAIEPRCLLALMDTLIHDGRTIDLSISSRLHAKVYAADYKIALLGSSNFSDGGFSTNIELLLKFVDDEADNILKKIETNLPQKLSNINLEEFNNWVSTSEPIIESLRKKPDDSPDELSEIQRSLDELFVPPAENPVNPQDYQSMDSFVEWLRGNEYLPGAKMLLARHFNTDGNNLTGHFKQCYYGALMFLDRNMKIVYYLTEELRTIKEDKIYQPSEDILEKWIEYFENHSSLRGDNYNFSVLRGYLPSSFGGTCYGGGGGISTFKRMLPLVAKYLSEVNDGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XT10</accession>
    <name>A0A0P6XT10_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Trk system potassium uptake protein TrkA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_07170</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062300.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07170"/>
    <dbReference type="EnsemblBacteria" id="KPL78245">
        <property type="protein sequence ID" value="KPL78245"/>
        <property type="gene ID" value="ADN00_07170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015079">
        <property type="term" value="F:potassium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006036">
        <property type="entry name" value="K_uptake_TrkA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02080">
        <property type="entry name" value="TrkA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02254">
        <property type="entry name" value="TrkA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00335">
        <property type="entry name" value="KUPTAKETRKA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51201">
        <property type="entry name" value="RCK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0630">Potassium</keyword>
    <keyword evidence="2" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="RCK N-terminal" evidence="5">
        <location>
            <begin position="2"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="6">
        <location>
            <begin position="139"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00017378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL78245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="224" mass="24702" checksum="A54855C03FDB01E0" modified="2016-01-20" version="1">MFVIVAGGGRLGAQLTRSLLAQDYQVHVVEDRPAVLSRLHRELPTETIFEGKVLDPKVLEAAGIQKANVVAACTAMDELNLAMCYEARTRYHVPRTVARVNDPNHAWLFNDMFKVDVAINQADIMSKILQEEMSMGDMITLMKLRRGNYSLIEEKIPPRAQAVGVSIMNLGLTDHCVIAAVIRKGEVTVPRGVTVLEAGDEILAITDQAGANRLAELLRAREDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XTH3</accession>
    <name>A0A0P6XTH3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_06645</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000018">
        <property type="protein sequence ID" value="KPL78400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062197.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000018.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78400">
        <property type="protein sequence ID" value="KPL78400"/>
        <property type="gene ID" value="ADN00_06645"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="94" mass="11017" checksum="169BF1C1D4A0CCCC" modified="2016-01-20" version="1">MKDKEIKYTGEYEDNILKMEAPVQLNEREIQAFIDLANRHPFVENCSYSHPDQIFIIEFDPGQELEPMDMVMLGTRFMDDAIFGYPVKINTPKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XTI2</accession>
    <name>A0A0P6XTI2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Lysine biosynthesis protein LysX</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_06695</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RimK family. LysX subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000018">
        <property type="protein sequence ID" value="KPL78409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062206.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000018.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06695"/>
    <dbReference type="EnsemblBacteria" id="KPL78409">
        <property type="protein sequence ID" value="KPL78409"/>
        <property type="gene ID" value="ADN00_06695"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2249"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009085">
        <property type="term" value="P:lysine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013651">
        <property type="entry name" value="ATP-grasp_RimK-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011870">
        <property type="entry name" value="LysX_arch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004666">
        <property type="entry name" value="RpS6_RimK/Lys_biosynth_LsyX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08443">
        <property type="entry name" value="RimK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02144">
        <property type="entry name" value="LysX_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00768">
        <property type="entry name" value="rimK_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="5">
        <location>
            <begin position="97"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00029440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL78409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="300" mass="33232" checksum="D80898814CB81F81" modified="2016-01-20" version="1">MHNSPRIGVLYSRVRVEEKWIFAALEERGVDYERLDDRNVYFDLDHPGSWLDYDALLERSISYARGLYALRVFGAWGIPTVNRLAVAEVCGDKIATSAALAAASVPQPRTKVAFTPESALEAIEEFGYPVVLKPSVGSWGRLLAKVNDRDAAEALLEHKSTLGSYQHSIFYIQEFIDKPGRDIRIFVVGDRAVTAIYRKSPHWITNTARGGEGEVCPITPDLEEICVRAAQAVGGGVLAIDVLEHPQRGFLINEVNHTMEFHTAQPTSGVDIAGIIVDYTLAVAKEHFERRGELVKESAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XU74</accession>
    <name>A0A0P6XU74_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AAA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062849.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09950"/>
    <dbReference type="EnsemblBacteria" id="KPL76911">
        <property type="protein sequence ID" value="KPL76911"/>
        <property type="gene ID" value="ADN00_09950"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2451"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="495"/>
            <end position="627"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="711" mass="78269" checksum="493F073633C2AD0E" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUF3</accession>
    <name>A0A0P6XUF3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Signal recognition particle receptor FtsY</fullName>
            <shortName evidence="5">SRP receptor</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ftsY</name>
        <name evidence="7" type="ORF">ADN00_14810</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Acts as a receptor for the complex formed by the signal recognition particle (SRP) and the ribosome-nascent chain (RNC).</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
            <orientation evidence="5">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the GTP-binding SRP family. FtsY subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000036">
        <property type="protein sequence ID" value="KPL73063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063811.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000036.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14810"/>
    <dbReference type="EnsemblBacteria" id="KPL73063">
        <property type="protein sequence ID" value="KPL73063"/>
        <property type="gene ID" value="ADN00_14810"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1825"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031226">
        <property type="term" value="C:intrinsic component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00920">
        <property type="entry name" value="FtsY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013822">
        <property type="entry name" value="Signal_recog_particl_SRP54_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004390">
        <property type="entry name" value="SR_rcpt_FtsY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036225">
        <property type="entry name" value="SRP/SRP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042101">
        <property type="entry name" value="SRP54_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43134:SF7">
        <property type="entry name" value="PTHR43134:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02881">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00963">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47364">
        <property type="entry name" value="SSF47364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00064">
        <property type="entry name" value="ftsY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00300">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-0132">Cell division</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 5" id="KW-0675">Receptor</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SRP54" evidence="6">
        <location>
            <begin position="274"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="107"/>
            <end position="114"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="189"/>
            <end position="193"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="253"/>
            <end position="256"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL73063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="302" mass="32671" checksum="8E05218F3E0DA76A" modified="2016-01-20" version="1">MLMFNKWLTGLDRTRKVAFGRISAFLGVSEINQNTWDDLEALLVQADLGIETSTDVIRALKQVVVENGLTRSEELSQVLKQELLNRLLPIPEPVLPDQKPLVILMVGVNGSGKTTTAAKLGKQFANQGKKVLLAAADTYRAAAVDQLQVWGERLNLPVVAGQPGGDPGAVAFDAIQSAAARGFDYVIVDTAGRLHTRYNLMEELKKVYRVSGKALSGAPHAVWLVLDATTGQNALQQAKAFKEAVQVTGIILSKLDSSARGGMAFAIQKTLGLPILYAGLGEKPEDLEHFDREAFVNGIFHN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUI8</accession>
    <name>A0A0P6XUI8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_10515</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77076">
        <property type="protein sequence ID" value="KPL77076"/>
        <property type="gene ID" value="ADN00_10515"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL77076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="103" mass="12236" checksum="A3FCA76D8FFFAC32" modified="2016-01-20" version="1">MTTKGKPFNRIPDFRRSERLPWCGPSINNSGDPIILKWDYQENKKIRTYVWLENFDYVIILEKKHIGNRVIAFLVTAFHVDGSRTKSQLKDKYRNRILMHSSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUV8</accession>
    <name>A0A0P6XUV8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_03585</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061595.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03585"/>
    <dbReference type="EnsemblBacteria" id="KPL78985">
        <property type="protein sequence ID" value="KPL78985"/>
        <property type="gene ID" value="ADN00_03585"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="24"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="277"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="390" mass="46808" checksum="9581563686D61C84" modified="2016-01-20" version="1">MDFEQIAKRLEWLDDERRKDKTTIATLEKRISALESAIPESRDQIKEINTQVARIEAALSRIDQLEESLAKIKVEHSRAIEVIEKQRVEREREADKVRREDLESLHKAIGETRKELEVLPDMRTKIQARIEEDYRLGRLISELEKKFDENVRSDEEYRRSIKLLEEGRRQDTKRLTDLQAETSVLRKRQDEQRGKVDVAADSVRKLELRVSEFAAMESERKQAQVAFIEKQSMQNLERERMWKEWQAQFETITRQTLDLESQMQALDATHRTVKRAQESFEETRQRFERRLNEITEMQRLVEERFRNEWVNFKSDDQKRWTNYTISQEEMQREANRKIEKQTERLVKVEDMTQEMHDTLESVLNDTRARLQKLLAFSQELMESNQQTFSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XV45</accession>
    <name>A0A0P6XV45_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Isocitrate dehydrogenase [NADP]</fullName>
            <ecNumber evidence="3">1.1.1.42</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_09435</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>D-threo-isocitrate + NADP(+) = 2-oxoglutarate + CO2 + NADPH</text>
            <dbReference type="Rhea" id="RHEA:19629"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.42"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.42" evidence="3"/>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062740.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09435"/>
    <dbReference type="EnsemblBacteria" id="KPL77332">
        <property type="protein sequence ID" value="KPL77332"/>
        <property type="gene ID" value="ADN00_09435"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4125"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004450">
        <property type="term" value="F:isocitrate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006097">
        <property type="term" value="P:glyoxylate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004439">
        <property type="entry name" value="Isocitrate_DH_NADP_dimer_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43504">
        <property type="entry name" value="PTHR43504"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00183">
        <property type="entry name" value="prok_nadp_idh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00470">
        <property type="entry name" value="IDH_IMDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0329">Glyoxylate bypass</keyword>
    <keyword evidence="3" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Iso_dh" evidence="4">
        <location>
            <begin position="29"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL77332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="433" mass="48081" checksum="C66042F1DE57B334" modified="2016-01-20" version="1">MSQPFFSPPFDAQPVTKPGDQLLVPDYPIIPFIEGDGIGRDIWRAARRVMDAAVEVAYGKQRKLGWMEVLAGEKANQLMQAWLPLETLEAFKTYKIGIKGPLTTPVGGGMRSLNVTLRKELDLFVCQRPVRYYQGVPSPVKNPQDVDMVVFRENTEDIYTGIEFQSGSEENERFLTLLKEHFPAEYAKIRFPGSSSVGIKPISKEGSQRLVRAAIRWALENQRRRVTLAHKGNIMKFTEGSFRAWGYDLAESEFGGRVYTQRAWEQTRKQAGEEAANAEMQRALSDGKLYVNDMIADIVFEATITRPRDFDVIATMNLNGDYLSDGLAAQVGGVGIAPGANINYDSGVAVFEATHGTAPLFADKDMANPCSLLLSGEMMLRYLGWREAAGLVVKGIEGALTAKTVTFDFERLMDGAVRLSTSEFATAIIQHMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XV54</accession>
    <name>A0A0P6XV54_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">2,4-dienoyl-CoA reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062750.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09490"/>
    <dbReference type="EnsemblBacteria" id="KPL77341">
        <property type="protein sequence ID" value="KPL77341"/>
        <property type="gene ID" value="ADN00_09490"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4137"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidored_FMN" evidence="1">
        <location>
            <begin position="7"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="414" mass="47301" checksum="2D8B26AA809CB2BE" modified="2016-01-20" version="1">MGYKETLLQPIMIGNRKCENRFFAQPMECVDSDEEGNPTELTYRRYENLFKGHFAFIDLEAITVTNESRARKTQLEIMPRNVKALTRFVRSLKEINPNALFVFQLTHSGEISEPDFSRRVTVKPVYGLGGDLLSEEEVDKIIDQFAEAAKIVQDVGADGVDMKLCHGYLGSQILRPYNDRPWKYGGAWENRAQFAYDLYERIRKATNFDKDFLIGSKISMWEAFPGGFGSAGPDSPLMDMREPIDLIKGLEERGAQYFVESLGNVHCSMEFMEAGSEDPYLSYLHMYFSKLMKDNLKPETVVVGSHFSSFRGKVNKLLSIEPEKSSMFAMGARCIEDGIVDMVGLGRQSFADPYTPLKLEEGREDEVKYCTQCLNCEELMIRQMPVGCVLYNKTYTELFREARKKYGKLAELHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XV84</accession>
    <name>A0A0P6XV84_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_04665</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061793.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04665"/>
    <dbReference type="EnsemblBacteria" id="KPL79150">
        <property type="protein sequence ID" value="KPL79150"/>
        <property type="gene ID" value="ADN00_04665"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.295"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000522">
        <property type="entry name" value="ABC_transptr_permease_BtuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30472">
        <property type="entry name" value="PTHR30472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01032">
        <property type="entry name" value="FecCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="123"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="158"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="199"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="244"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="289"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="316"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL79150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="343" mass="36365" checksum="311026F0A83EEBDC" modified="2016-01-20" version="1">MPMLTARRIPLIPLLLLAACLIASVAVGSVFIPPTTLLGLLGARLSGQTIPADWQPFAAIIFDLRLPRTVLIALTGAALAGSGASYQGLFRNPLADPYLIGVASGAGLGAVLAMSVRWPYTLWGLLAIPTFAFLTALLTVLVVYQLARVGATLPITNLILAGVAISSFTTALTSYLMINASGELRRALVWLLGGASQTGWQPVLVIFPFILVGLGILASLGHALNVLQFGDEQAQQLGLPVNRVRWLVILAASLTTAAAVSFAGIIGFVGLIVPHTVRLIWGPDYRRLIPLSIVNGATLLLCADILARLVLAPREVPVGIITAMAGAPFFLWVLRRAKQQNYW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XVA7</accession>
    <name>A0A0P6XVA7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01495</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061191.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80545">
        <property type="protein sequence ID" value="KPL80545"/>
        <property type="gene ID" value="ADN00_01495"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="214"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="256"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="297"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="330"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="363"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="387"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="682" mass="77279" checksum="1A26AD7335556134" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XVE2</accession>
    <name>A0A0P6XVE2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_05120</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061878.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05120"/>
    <dbReference type="EnsemblBacteria" id="KPL79223">
        <property type="protein sequence ID" value="KPL79223"/>
        <property type="gene ID" value="ADN00_05120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="111"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="442"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="154"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="574"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL79223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="574" mass="62967" checksum="45DBC5211A5D8823" modified="2016-01-20" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XVG9</accession>
    <name>A0A0P6XVG9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NTP_transferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01760"/>
    <dbReference type="EnsemblBacteria" id="KPL80600">
        <property type="protein sequence ID" value="KPL80600"/>
        <property type="gene ID" value="ADN00_01760"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1114"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NTP_transferase" evidence="1">
        <location>
            <begin position="8"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="333" mass="36993" checksum="2F304DCCAF2E3B4C" modified="2016-01-20" version="1">MKIAVPMAGFGTRMRPHTWSKPKPLVPIAGRTVLDYALDQFKSLPVDWDVEYIFITGEQGKAPIQKHMEKFHPEKKVQYLIQAVMRGQSDALYLARDYLKGPTLMAFSDTLIETDLSFLAAENADGLAWVKPVPDPRRFGVAQVTPEGRVTRLIEKPQDISNNLVIVGFYYFKNGEDLIDAIEEQMRRGTTLKGEYFLADAVNILLERGQIFRTVPVEIWLDAGIPETTLETNGYLLHHGCDNSQRYAGQDGLVVVPPVYIDPSAEVSHAVIGPNVSIGANCKVSEAVIRNSIIGDESTIDQMILTDSLIGDRVILTGQPDRLNVGDNSQITR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XWM1</accession>
    <name>A0A0P6XWM1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA-binding protein KhpA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">KH-domain protein A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">khpA</name>
        <name evidence="2" type="ORF">ADN00_08255</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">A probable RNA chaperone. Forms a complex with KhpB which binds to cellular RNA and controls its expression. Plays a role in peptidoglycan (PG) homeostasis and cell length regulation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Forms a complex with KhpB.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the KhpA RNA-binding protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062512.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08255"/>
    <dbReference type="EnsemblBacteria" id="KPL77862">
        <property type="protein sequence ID" value="KPL77862"/>
        <property type="gene ID" value="ADN00_08255"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.653"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00088">
        <property type="entry name" value="UPF0109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020627">
        <property type="entry name" value="KhpA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34654">
        <property type="entry name" value="PTHR34654"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0133">Cell shape</keyword>
    <keyword evidence="1" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="79" mass="8796" checksum="021669F69CF5FD46" modified="2016-01-20" version="1">MKELVEYIAKSLVEHPEEVFVKQERAGGNKVRLELRVAKDDMGRVIGKSGRVANSARILLRVAAAREGKQANLDVVEPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XWN4</accession>
    <name>A0A0P6XWN4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hemolysin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_08315</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TlyA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062521.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08315"/>
    <dbReference type="EnsemblBacteria" id="KPL77871">
        <property type="protein sequence ID" value="KPL77871"/>
        <property type="gene ID" value="ADN00_08315"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.665"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004538">
        <property type="entry name" value="Haemolysin_A/TlyA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002877">
        <property type="entry name" value="RNA_MeTrfase_FtsJ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32319:SF0">
        <property type="entry name" value="PTHR32319:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01728">
        <property type="entry name" value="FtsJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005578">
        <property type="entry name" value="TlyA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00478">
        <property type="entry name" value="tly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S4" evidence="2">
        <location>
            <begin position="4"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="264" mass="29101" checksum="7F02A69E9A376BF2" modified="2016-01-20" version="1">MQKERLDVLLMERGLVESRSLAQRLIMAGEVRVNGQPVLKPSIRVDDQALIEIEQGPKFVSRGGEKLEAALIAFGLTDLHDLVCVDVGASTGGFTDCLLQYGAKRVYAVDVGYGVLHWKLRNHPAVVSMERTNARHVENFPEVVQLVTIDASFISLKVLLPAVKRWFGERSGRTVVLVKPQFEAGKKDADKGEGVIRDPAIHRQVLLSVLESAQEEGFAVEGLIRSPLQGPKGNIEFLANLAFPLQTLADLHPMVDRVLPLIEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XWW7</accession>
    <name>A0A0P6XWW7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PALP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_08550</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062566.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08550"/>
    <dbReference type="EnsemblBacteria" id="KPL77908">
        <property type="protein sequence ID" value="KPL77908"/>
        <property type="gene ID" value="ADN00_08550"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.714"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PALP" evidence="3">
        <location>
            <begin position="65"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL77908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="367" mass="39947" checksum="37324365C6177F85" modified="2016-01-20" version="1">MAEIRCTQCNQVYPTRGLPFRCASCGGVYDFDGPPNYDPELVERDLPGIWRYRHSFDLFKNAPVISLGEGRTPLIWERLRGLDIGLKMESQNPSGSYKDRATAVLVSQLLSRGTRLAVEDSSGNAGASFAAYAARGRMSARIFVPSTASGPKLRQIEAYGAELRPVLGPRSAAAQEALQEALDGTVYASHAYLPFGLPGIATLSYELMEQLGREPGTVIAPAGHGSLLLGIIRGFESLQRGGLIERQPYYIGVQAKSCAPIWYYFTQGWDAYNAVREGKTIAEGVRVRHPVRLRALREEILPGGGEIIAIDEDEILLAHTDLGKRGISVEPTSALVWSAVQQAIGRVPEPIVLVLSGSGLKYYKPSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XXV6</accession>
    <name>A0A0P6XXV6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N_BRCA1_IG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_06975</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062263.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78219">
        <property type="protein sequence ID" value="KPL78219"/>
        <property type="gene ID" value="ADN00_06975"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14947">
        <property type="entry name" value="NBR1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032350">
        <property type="entry name" value="N_BRCA1_central"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16158">
        <property type="entry name" value="N_BRCA1_IG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133268" description="N_BRCA1_IG domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="N_BRCA1_IG" evidence="3">
        <location>
            <begin position="127"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL78219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="223" mass="23795" checksum="96EE81FF1D93130D" modified="2016-01-20" version="1">MKTQKIVAFCVMAAALVLAGCAGTPEPTIDPNVVYTQAASTVQAQLTETAAAMPTATQTPEPTATPVPPTATPTEILPTLPPVGSGGESTAVATATSAPTYSAGSTNPAPGKQTGDAATWGYNQPGDNQTFKPNEEFLLSWGFTNTGTTTWKPGYKWVFVSGQSLSGVKEVVLDREIKPGEKWEANIRAFLPGEEGTYISRWYLYNASGQFIEEFYFPFKIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y2P8</accession>
    <name>A0A0P6Y2P8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 2">Hypoxanthine phosphoribosyltransferase</fullName>
            <ecNumber evidence="1 2">2.4.2.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_04965</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>diphosphate + IMP = 5-phospho-alpha-D-ribose 1-diphosphate + hypoxanthine</text>
            <dbReference type="Rhea" id="RHEA:17973"/>
            <dbReference type="ChEBI" id="CHEBI:17368"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="EC" id="2.4.2.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; IMP biosynthesis via salvage pathway; IMP from hypoxanthine: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.8" evidence="1 2"/>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061847.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04965"/>
    <dbReference type="EnsemblBacteria" id="KPL79197">
        <property type="protein sequence ID" value="KPL79197"/>
        <property type="gene ID" value="ADN00_04965"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.360"/>
    <dbReference type="UniPathway" id="UPA00591">
        <property type="reaction ID" value="UER00648"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052657">
        <property type="term" value="F:guanine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004422">
        <property type="term" value="F:hypoxanthine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032264">
        <property type="term" value="P:IMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005904">
        <property type="entry name" value="Hxn_phspho_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01203">
        <property type="entry name" value="HGPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="3">
        <location>
            <begin position="18"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU364099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL79197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="190" mass="21789" checksum="CA9509FD6C548669" modified="2016-01-20" version="1">MRDAPKFPYAFIDKIIVSQEEIDQRVCELGETITRDYANSENLLLLGLLRGSVMFITDLMRKIHRPMTMDFMSVSSYAGSESSGFVRIDSDHKTNIHGWDVILVDDIVDSGFTVHTVRKLLLDRKPNSIKVCALLDKPDRHKVDIHIDYLGFSIPDYFVVGYGLDIDEKGRNLPYIASVDLEKFKQIYKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y3D0</accession>
    <name>A0A0P6Y3D0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_02600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000012">
        <property type="protein sequence ID" value="KPL79425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061402.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000012.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02600"/>
    <dbReference type="EnsemblBacteria" id="KPL79425">
        <property type="protein sequence ID" value="KPL79425"/>
        <property type="gene ID" value="ADN00_02600"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="504" mass="57708" checksum="0F930DB30089954A" modified="2016-01-20" version="1">MIKIKYLQEPALQFGGYFEHQDAKTGLSEFGPFGKNIPGLHPTEINLGFIGTRETVSWAQEWIERCGEYIESENIKRNKPSTSQSIEGQLFDTEALFDSPQTLNRLEKILTPDFIGFNNDSAFNCSFQTNDRWVRYIQPRELIEILALDNKTDIIWKMVNLFDENIANIAANDPTPDIIILALPPEIENKAHSVRISGNYFLNFRRAIKARSMKWNIPLQLITKSTVTGEGKNVQDVATRAWNFCTAQYYKANGVPWRITSLDEATCFIGVSFFIAKDLSDIVTMRSSVAQAFDFMGQGLILRGDYFNWDVQRLGKTPHLTYDGAKKLVKDTLNEYIRLKGYPPRRVVIHKTSEFWGKEHIDFNELDGFQNGINEVFGRCEIDLVSLAQSGVRLFREGKYPPLRGTYFSINNAYHLLFTMGYIPFLETFPKPYVPEPWQIMQHIGGSSPEDLFKEILALTKMNVNNCAFADGSPITLSFSRMVGEIMKHIPENGIVQPKYRFYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y4G2</accession>
    <name>A0A0P6Y4G2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N_BRCA1_IG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_10985</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063059.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10985"/>
    <dbReference type="EnsemblBacteria" id="KPL76492">
        <property type="protein sequence ID" value="KPL76492"/>
        <property type="gene ID" value="ADN00_10985"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14947">
        <property type="entry name" value="NBR1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032350">
        <property type="entry name" value="N_BRCA1_central"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16158">
        <property type="entry name" value="N_BRCA1_IG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133352" description="N_BRCA1_IG domain-containing protein" evidence="2">
        <location>
            <begin position="19"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="N_BRCA1_IG" evidence="3">
        <location>
            <begin position="113"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL76492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="391" mass="42329" checksum="3A51EA14C9E702B5" modified="2016-01-20" version="1">MKKTVLPLFIIGLAVLMAACFPQLPVPDTGDGLVETAAAQTVDVMFTQAAFKTLVAQVTQMSAVTATPFPTATLAPTQTPFPPTSTPVPTQVPPTPTNTPVPCDWAKFEADVTVPDGSKYERGVSFTKTWRLRNIGSCAWTTDYDLVFDTGHAMNGPVAVALPKRVNPGETVDISVTLVAPDGEGEYTGNWKLRNASNAVFGLGPNANKPFWVKIEVERSDREWDKDKTLDFAKYYCDASWKSSKGSVACPSASESFKNGSVSRSSAPKLEGGYQDDEPAIIMIPSEGDDGMIQGKFPAFKVKDGDRFTALTGCLDNSDDCDVTFKLEYIADGGSVQNLKSWTEKSDGERTSINVDLSSLKDKAVQLILVVDNNNDSDDDRAFWLAPVIKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y619</accession>
    <name>A0A0P6Y619_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ABC2_membrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_10740</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062996.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77031">
        <property type="protein sequence ID" value="KPL77031"/>
        <property type="gene ID" value="ADN00_10740"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006648">
        <property type="entry name" value="DrrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="60"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="104"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="145"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="229"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="6">
        <location>
            <begin position="26"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL77031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="267" mass="28982" checksum="1A70F3DC4EEF8820" modified="2016-01-20" version="1">MLRQLTVNIRIFWQGTLLSYIGMFHWLRPTTYLASKVLMPLAQILFFTLLGIYASGRENASFYVIGNAVQISAVSGIYGVTMSIGGDRWNGTLPYLFGTPANRFFLFVGRAFMHVIDGMLGVVVGLMWGVLLLGLDLSNTDLPALALTILVTTISCSGMGLLMGCVGLITTNIMFVNNSVYFLLLIFSGANIPVDRLPVVFQVLAQGLPLTRGITSARALIAGASLESVLPLLLGELAVGLAYGLAGFWLFRWFETKAKQKGTLETV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y710</accession>
    <name>A0A0P6Y710_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Pyridoxal-dependent decarboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_09515</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the group II decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062779.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09515"/>
    <dbReference type="EnsemblBacteria" id="KPL77369">
        <property type="protein sequence ID" value="KPL77369"/>
        <property type="gene ID" value="ADN00_09515"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4142"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016830">
        <property type="term" value="F:carbon-carbon lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="3">
        <location>
            <position position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR602129-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL77369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="460" mass="50156" checksum="50DD5635143B794F" modified="2016-01-20" version="1">MQAKMLRLAQERDLFEQAKSYAYDYMARAFKRNVFPSEAALKNLSVFDEPLTELPGDPAEMLRMLHEYGSPAAVTSTGGRYFGFVVGSVFPPVMAAKWLGDVWDQLTALYVSSPIMAKLEAVSEKWLVELFGLPPQTVAGFVSGSSMAIVCGLAAARYELLKRAGWDVNAQGLFGAPPIRVVVGAEAHSTVFKALALLGLGKERVELAPVDEQGRMLVSQLPKLDSNTLVILQAGNVNSGSFDPLDELCDKANAAGAWVHVDGAFGLWAAASANQRHLTRGLEKADSWSVDAHKTLNTPYDSGIALCKHRDALVSALQATGAYILYSENRDGMLYTPEMSRRGRSLEIWATLKILGKSGVEELVDGLCQRARQFADQMRAQGFRVLNEVVFNQVLIACDTPEETTSTLQKLQRAGECWCGAGNWHNTPVMRVSVCSWATTAEDIDRSVAAFVKAREEAQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y7P3</accession>
    <name>A0A0P6Y7P3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_08695</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000022">
        <property type="protein sequence ID" value="KPL77662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08695"/>
    <dbReference type="EnsemblBacteria" id="KPL77662">
        <property type="protein sequence ID" value="KPL77662"/>
        <property type="gene ID" value="ADN00_08695"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004477">
        <property type="entry name" value="ComEC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025405">
        <property type="entry name" value="DUF4131"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03772">
        <property type="entry name" value="Competence"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13567">
        <property type="entry name" value="DUF4131"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00360">
        <property type="entry name" value="ComEC_N-term"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="240"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="268"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="339"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="378"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="420"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="467"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="502"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4131" evidence="8">
        <location>
            <begin position="12"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="Competence" evidence="7">
        <location>
            <begin position="218"/>
            <end position="493"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL77662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="716" mass="77356" checksum="FE6CF3955B78A02E" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GKK7</accession>
    <name>A0A0N8GKK7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phosphate-specific transport system accessory protein PhoU</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_18025</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Plays a role in the regulation of phosphate uptake.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PhoU family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL69970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064436.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18025"/>
    <dbReference type="EnsemblBacteria" id="KPL69970">
        <property type="protein sequence ID" value="KPL69970"/>
        <property type="gene ID" value="ADN00_18025"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2906"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030643">
        <property type="term" value="P:cellular phosphate ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045936">
        <property type="term" value="P:negative regulation of phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028366">
        <property type="entry name" value="P_transport_PhoU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038078">
        <property type="entry name" value="PhoU-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026022">
        <property type="entry name" value="PhoU_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42930">
        <property type="entry name" value="PTHR42930"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01895">
        <property type="entry name" value="PhoU"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003107">
        <property type="entry name" value="PhoU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02135">
        <property type="entry name" value="phoU_full"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PhoU" evidence="2">
        <location>
            <begin position="20"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="PhoU" evidence="2">
        <location>
            <begin position="120"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR003107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL69970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="217" mass="24707" checksum="38B40A019F1E6C7F" modified="2016-01-20" version="1">MPRNSLDKKILAIKNDVLFLHGMVQRATTAALGALMRKDFRASESIYRNDFLINDKRIEIEYACLLLISTQQPLADDLRLLASTLEVITDLERMGDYAKGIAKINLLIGKEPFLEPVQYLPEMKDRALSMLERGVEAFIKCDQDLALKIPREDTAVDNLYQALYHDLMSLTAQDSSHNEQANHLLWAGHNLERMADRVSNICIRTNFVITGKIIDFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GKM0</accession>
    <name>A0A0N8GKM0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA polymerase sigma factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_18675</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064555.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70074">
        <property type="protein sequence ID" value="KPL70074"/>
        <property type="gene ID" value="ADN00_18675"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000838">
        <property type="entry name" value="RNA_pol_sigma70_ECF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01063">
        <property type="entry name" value="SIGMA70_ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="3">
        <location>
            <begin position="25"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="4">
        <location>
            <begin position="134"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL70074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="202" mass="22947" checksum="08062DB6FA9050D0" modified="2016-01-20" version="1">MTEPLELSISIDVLKAGNKAEFAKLVNQYSNSVYRIALKILSDPSDAEDVLQETFIKAFRALPGFEGRSSISTWLFRIATNEALMLVRKRKPDFVLVDEPDAPDEDENSGQVQLTDWCCMPEAELMSDESRRHLEEAVQDLTPALRAVFVLRDIEGLSIKETAEALDVSEQVVKTRLLRARLRLREDLSRYFGGKMAERLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GLD2</accession>
    <name>A0A0N8GLD2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Polyphosphate glucokinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_15160</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063881.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15160"/>
    <dbReference type="EnsemblBacteria" id="KPL72170">
        <property type="protein sequence ID" value="KPL72170"/>
        <property type="gene ID" value="ADN00_15160"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.734"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="250" mass="27092" checksum="99E131C50A105F09" modified="2016-01-20" version="1">MSVLGIDIGGSGIKGALVDVETGQLLTPRERIPTPEPATPERVAVVFAELVKKLKYEGPIGAGFPAIIQQGVAYSAANVHEEWINTNAEKLFSQKTAQPVYVLNDADAAGLAEMKFGAGRDFYKGTVLMVTLGTGIGSAIFTNGHLLPNVEFGHLKVRGKDAEHRASDAARKSQELTWKKWSKRLQEVLDYMEALVSPDVIIVGGGVSKDYQKYFPYLSTKAKLLPAQFLNQAGIVGAALYAWMRSRGEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMR5</accession>
    <name>A0A0N8GMR5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">DNA repair protein RadC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_11800</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the UPF0758 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063217.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11800"/>
    <dbReference type="EnsemblBacteria" id="KPL76034">
        <property type="protein sequence ID" value="KPL76034"/>
        <property type="gene ID" value="ADN00_11800"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3836"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08071">
        <property type="entry name" value="MPN_DUF2466"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025657">
        <property type="entry name" value="RadC_JAB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001405">
        <property type="entry name" value="UPF0758"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020891">
        <property type="entry name" value="UPF0758_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30471">
        <property type="entry name" value="PTHR30471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04002">
        <property type="entry name" value="RadC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00608">
        <property type="entry name" value="radc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01302">
        <property type="entry name" value="UPF0758"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MPN" evidence="7">
        <location>
            <begin position="111"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL76034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="236" mass="25480" checksum="5E755DB0A64EB80D" modified="2016-01-20" version="1">MPKDNGSIGYRITDLESNDRPCERLAEVGAQALSNAELLAILLRVGIPGENAVQLGGRLLRDLKGLSGIHQASFDEVCQQKGVGPAKAAQIKAAIELGRRLQAFTGDDRPAIHSPQDAADLVMFEMSALLQENLWVLHLDTRNRVVHTDRIYKGSLNSSTVRVGELFKAAIQRNAAAVILVHNHPSGDPGPSPEDIQLTRAAVQAGKLLDIKVLDHLVIGHGRFVSLKERGLGFDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMY2</accession>
    <name>A0A0N8GMY2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_11490</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063155.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76570">
        <property type="protein sequence ID" value="KPL76570"/>
        <property type="gene ID" value="ADN00_11490"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.999"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL76570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="306" mass="32964" checksum="392B502549FC2C68" modified="2016-01-20" version="1">MIRVQDLQKAYGNVQALRGVSFDIAQGEIVGLLGPNGAGKTTIIKTITGFLQPDAGVVEVDGIDVMQDPRGVQARIGYLPENAPLYPELTVQATLQLAADLREIPEDAQLEKISRAVYAVGLEKHLTRPIGTLSKGFRQRVGLAQAILHQPPLLILDEPTVGLDPRQIVEIRGLIKSLAGQSTVLFSTHILPEVEALCDRVIILMNGEIRANARLDELAATGNAVVVLGERPAGAESLLRGLPGVEKVEAFENGDAHPAYRVLGNNGADLTPAIYQLAAANGWRLRELRRDTRSLESIFNEIAMAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GN75</accession>
    <name>A0A0N8GN75_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_09305</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77314">
        <property type="protein sequence ID" value="KPL77314"/>
        <property type="gene ID" value="ADN00_09305"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL77314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="103" mass="12155" checksum="62D0BC63C4C646D4" modified="2016-01-20" version="1">MILIGMYNASEIDQIKGPKMKKINNERRGFLIKQIPIRMINGITNDNFSCINTNNPQIMEAIIMKTALSFFNILKVSIDVLYINYIKFKFLDETFFTYRFINF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNK6</accession>
    <name>A0A0N8GNK6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cyclic nucleotide-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_07725</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07725"/>
    <dbReference type="EnsemblBacteria" id="KPL78362">
        <property type="protein sequence ID" value="KPL78362"/>
        <property type="gene ID" value="ADN00_07725"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="14"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="4">
        <location>
            <begin position="239"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="50"/>
            <end position="57"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL78362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="373" mass="41242" checksum="878EF5FA875FBF8A" modified="2016-01-20" version="1">MPVVQTTGESQPIVRIRDLVKTYSSTAGDFTVLKNIHVDFYPGEFVGVIGKSGSGKSTLINMITGIDRPTQGEVYVGNVAVHSMSENEMAIWRGRNMGIVFQFFQLLPMLSLLENVMLPMDFCNMYSVPERYERAMYLLRMVEMQDHANKLPSAISGGQQQRVAIARALANDPPVIVADEPTGNLDSKTAEAVFAMFEQLIDRGKTIVMVTHDSSLAKRVTRTVLIADGEVVNEYVFRAMPTLTHQQMLHVTKELVPMTFEPGQVIMRESDPGDHFYIVTEGEVEIALKRPDGVDVVVTRLGPGKYFGEIELMQDRSAVATVRAAASGVKVAALDHADFDALLAESEQTRNAMEYNASKHLNENVSARDGEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNT6</accession>
    <name>A0A0N8GNT6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hydroxydechloroatrazine ethylaminohydrolase</fullName>
            <ecNumber evidence="2">3.5.99.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_03675</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.99.3" evidence="2"/>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061612.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03675"/>
    <dbReference type="EnsemblBacteria" id="KPL79002">
        <property type="protein sequence ID" value="KPL79002"/>
        <property type="gene ID" value="ADN00_03675"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.87"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="1">
        <location>
            <begin position="57"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="462" mass="50300" checksum="986EE8C7645723F9" modified="2016-01-20" version="1">MSTLLVKNANLIVTMDDHRSEILNGGLFCRDGFIEQVGATNDLPSQADEVLDLSGHIVLPGLINTHHHFYQTLTRVVPAAQDVNLFHWLKTLYPIWARMNPEDIFISTKTALAELALSGCTTASDHLYLFPNGSRLDDEIAAAQEMGMRVHASRGSMSLGESKGGLPPDSVVDTEEHILKDSVRLIERYHDPKPGSMVQIVLAPCSPFSVTGELMKESAKVARQYGVHLHTHLAETKDEEVFCEEKFGYRPVAYMQSVDWVGNDVWFAHSVHIQPEEIQVYVREGCGVAHCPSSNMRLASGIAPVWEYLQAGVKLGLGVDGSASNDGSHMLAEARQMLMLARVRAGVMGASLSQDGAPPILTARQALEAATLGGAAVLGRTDIGSLQAGKCADFVAFDLRQLDYAGGLHDPVAALLFCNPTKVSYNYVAGKAVVREGQFVNLNLEKHIERHNQAAKRLVLGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNW2</accession>
    <name>A0A0N8GNW2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_05035</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061861.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79210">
        <property type="protein sequence ID" value="KPL79210"/>
        <property type="gene ID" value="ADN00_05035"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="82" mass="9466" checksum="FD5D8CDCFD18A05D" modified="2016-01-20" version="1">MLYTSPQLILTHHHARVESALRAGRDAERLRQLPESTWQMDRMNYLILKLSDLFLVKKMLAFTRPAMSMRINQPGQAACSPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GP76</accession>
    <name>A0A0N8GP76_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PK_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01805</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000006">
        <property type="protein sequence ID" value="KPL80122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061252.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000006.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01805"/>
    <dbReference type="EnsemblBacteria" id="KPL80122">
        <property type="protein sequence ID" value="KPL80122"/>
        <property type="gene ID" value="ADN00_01805"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1380.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015074">
        <property type="entry name" value="DUF1867"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015795">
        <property type="entry name" value="Pyrv_Knase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036918">
        <property type="entry name" value="Pyrv_Knase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02887">
        <property type="entry name" value="PK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016138">
        <property type="entry name" value="UCP016138"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52935">
        <property type="entry name" value="SSF52935"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PK_C" evidence="1">
        <location>
            <begin position="22"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="196" mass="21401" checksum="034BF7E262ECB624" modified="2016-01-20" version="1">MQEITSQTAYFSQPGDENTLRVFEMTLQRVKALQVNTLLVATTTGKTAALAARFFKDCKVIAVTHSAGFQYENLLELQPEHRDHILQAGGQILTCQHAFGGINRAIRYKLGAYQVDEVIAYTLRLFGQGMKVVVETALMAADSGLVRTDQPVISIGGTCHGADTAVALLPANAQNFFDLKILEVICLPSPHHPAFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WKB8</accession>
    <name>A0A0P6WKB8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Dihydroorotate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_19225</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064657.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70161">
        <property type="protein sequence ID" value="KPL70161"/>
        <property type="gene ID" value="ADN00_19225"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3156"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046873">
        <property type="term" value="F:metal ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="78"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="122"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="153"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="221"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="251"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL70161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="270" mass="28364" checksum="2FEB18C5319FEFAF" modified="2016-01-20" version="1">MIEAIRTFNPIVQALLATLFTWGLTALGAAGVFLTKEINRRLLDAMLGFASGVMIAASFWSLLAPAIEMTESNGGTPWVPALIGFLAGGGFLYLVDRILPHLHLGLPIDEAEGIKTSWQRSILLVLAITLHNFPEGLAVGVAFGAAAAGVSEASLSAAVALAIGIGIQNFPEGLAVSAPLRREKMSRWRSFMIGQASGMVEPVAGVLGAAAVYFIRPLLPYALAFAAGAMIYVVIEELIPEAQLNKDTDLPTLGAMLGFAVMMMLDVALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WKC3</accession>
    <name>A0A0P6WKC3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ADN00_18605</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18605"/>
    <dbReference type="EnsemblBacteria" id="KPL70171">
        <property type="protein sequence ID" value="KPL70171"/>
        <property type="gene ID" value="ADN00_18605"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3030"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="151"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="256"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="36"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="386"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="423"/>
            <end position="430"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL70171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="637" mass="69646" checksum="88C6D3A09CAD9E6D" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WMW5</accession>
    <name>A0A0P6WMW5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Response regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_19200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064653.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_19200"/>
    <dbReference type="EnsemblBacteria" id="KPL70158">
        <property type="protein sequence ID" value="KPL70158"/>
        <property type="gene ID" value="ADN00_19200"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3152"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="4"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="376"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="380"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL70158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="405" mass="44249" checksum="4F8A3A9954C4A9E4" modified="2016-01-20" version="1">MVERILAVDDNPVNLKVVSATLKQAGFEVATAGNGSEALEQVKIVKPALIILDINMPDMDGYEVCRRLRAMPATANTPIVMLTAHDSLEEKIKGFEAGADEYITKPFQPAELQARVKVLLRRVAVARPEKVQKTSKVIAVFSLRGGVGVSTFATNLAVGLSQLWKEPVALVDMVLTMGQSALMLNLPLRNTWGDLAKIPSEELESDLLQSVLLNHDSGVSVLAAPRTYVEGETVTPAIATRVLELLRGNFPYVVLDLPHDFRETTLAGLDAADEIIVLIAPELASVRAVVGALEVFDELGYGREKIRIVMNWTFERKGLARKDIENVMKHPIQYVVPFVPDGFVSAINLGIPPVLGEPETPVGALFEDFAFALSKPEDKESPSASPSPAYQRVLERSKSRQHSKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WR96</accession>
    <name>A0A0P6WR96_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Flagellar protein FliL</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_17220</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 8">Controls the rotational direction of flagella during chemotaxis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the FliL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064289.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17220"/>
    <dbReference type="EnsemblBacteria" id="KPL71429">
        <property type="protein sequence ID" value="KPL71429"/>
        <property type="gene ID" value="ADN00_17220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005503">
        <property type="entry name" value="FliL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35091">
        <property type="entry name" value="PTHR35091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03748">
        <property type="entry name" value="FliL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="8" id="KW-0283">Flagellar rotation</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL71429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="206" mass="22286" checksum="96DEDAED03619ACC" modified="2016-01-20" version="1">MEKVSNILSLVLKILAVLVLLITAAFSMATAYIMFAPDDYPKPFYLQYLYPTAESGTLLPASEHSSGTVAQAVVEPVLAQPGSGVMINTGTKIINLTDPSGRKYIRVAVVLEFNPPAVDPEAEESGGAHGGEETATDPITEFTTEITAKLPVIDDNIITLLSSKSFEQLYTAEGKEGLRNEIRDRINQALPGYTVIAVYFTEFVVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WSR6</accession>
    <name>A0A0P6WSR6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_16360</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064113.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72051">
        <property type="protein sequence ID" value="KPL72051"/>
        <property type="gene ID" value="ADN00_16360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="72" mass="8406" checksum="2AF54D9820E909D2" modified="2016-01-20" version="1">MATDGIYRYEIRVKGEMQEYWLSRFSGLDFSLDTEGNTCMLGSMDQATLFGILNLICDIGMRLDWVMRHEME</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WTV9</accession>
    <name>A0A0P6WTV9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Abasic site processing protein</fullName>
            <ecNumber evidence="7">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_19195</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the SOS response-associated peptidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="7"/>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064652.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_19195"/>
    <dbReference type="EnsemblBacteria" id="KPL70157">
        <property type="protein sequence ID" value="KPL70157"/>
        <property type="gene ID" value="ADN00_19195"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3151"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006974">
        <property type="term" value="P:cellular response to DNA damage stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018142">
        <property type="term" value="P:protein-DNA covalent cross-linking"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1680.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003738">
        <property type="entry name" value="SRAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036590">
        <property type="entry name" value="SRAP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13604">
        <property type="entry name" value="PTHR13604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02586">
        <property type="entry name" value="SRAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143081">
        <property type="entry name" value="SSF143081"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0190">Covalent protein-DNA linkage</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL70157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="232" mass="26440" checksum="5258056BBEAC57F9" modified="2016-01-20" version="1">MCGRFTITIEAAALQLELGLAETPLEWKPRFNVAPTQPVAVVRDPNLQRLEYMRWGLVPSWAKDVEIGNRLINARSETIEEKPSFRTSFSRRRCLIPADGFYEWQRGKERKTPAQPYYFFLKDHALFAFAGIWDLWQSPDGSELTSCSIITCAANDLVSRYHERMPVILAPGAYQEWLGESNVGLLKQMLTPYPAERMDAYAVSTQVNSAWEDTPQLILPLEQKPPAATLFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WV24</accession>
    <name>A0A0P6WV24_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Cation transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_13985</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063648.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000033.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13985"/>
    <dbReference type="EnsemblBacteria" id="KPL74111">
        <property type="protein sequence ID" value="KPL74111"/>
        <property type="gene ID" value="ADN00_13985"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027470">
        <property type="entry name" value="Cation_efflux_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036837">
        <property type="entry name" value="Cation_efflux_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16916">
        <property type="entry name" value="ZT_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160240">
        <property type="entry name" value="SSF160240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="SSF161111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="122"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="ZT_dimer" evidence="7">
        <location>
            <begin position="219"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL74111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="298" mass="32370" checksum="BCD4FFDF9FEB5CAF" modified="2016-01-20" version="1">MRWIRSYTPDPTQQRLYRQALIITGVGNLTLAAGKAVAAYLTGSAALYADAANSVSDVVYSALMILGLWVAMQPPDLSHPQGHSRFEPLVGLMVTLSMTLAGYEAARTAIERFLEGGLRVELGLPAIVLLIAAGIKAWMYVSVARLARQLHSPTLETTARDNLSDVLTSSAAFIGAAGSQFIHPLADPIAGLIVAIWIFRNAFLAGRENLNFLTGAGADEELRQEIVRKVESVEGVQRVHFMVTEYVGPKLVVDVHANVDGSMSLDAAHEINDQVIELLEDMAEVDRAYVHLEPEHED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WVU6</accession>
    <name>A0A0P6WVU6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DhaL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13770"/>
    <dbReference type="EnsemblBacteria" id="KPL74385">
        <property type="protein sequence ID" value="KPL74385"/>
        <property type="gene ID" value="ADN00_13770"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1331"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004371">
        <property type="term" value="F:glycerone kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006071">
        <property type="term" value="P:glycerol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019986">
        <property type="entry name" value="DAK2_dom-cont_prot_YloV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004007">
        <property type="entry name" value="DhaL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036117">
        <property type="entry name" value="DhaL_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033470">
        <property type="entry name" value="UPF_DhaK"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13684">
        <property type="entry name" value="Dak1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02734">
        <property type="entry name" value="Dak2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01121">
        <property type="entry name" value="Dak1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01120">
        <property type="entry name" value="Dak2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101473">
        <property type="entry name" value="SSF101473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03599">
        <property type="entry name" value="YloV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51480">
        <property type="entry name" value="DHAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DhaL" evidence="1">
        <location>
            <begin position="4"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="539" mass="58143" checksum="29EB38B4D2D44500" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WXW9</accession>
    <name>A0A0P6WXW9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA_binding_1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_16755</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064200.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16755"/>
    <dbReference type="EnsemblBacteria" id="KPL71358">
        <property type="protein sequence ID" value="KPL71358"/>
        <property type="gene ID" value="ADN00_16755"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06445">
        <property type="entry name" value="ATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014048">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036217">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNAb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01035">
        <property type="entry name" value="DNA_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46767">
        <property type="entry name" value="SSF46767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_binding_1" evidence="1">
        <location>
            <begin position="7"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL71358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="108" mass="11751" checksum="3C448EB6E4F2D675" modified="2016-01-20" version="1">MSESHPLYQRIYALVRQIPPGKVATYGQIARLVGGCTPRMVGYAMAAVPNGSDVPWQRVINSRGGISPRANPFGELAQRALLEAEGIRFDENGRADLETCAWLGPDLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZ79</accession>
    <name>A0A0P6WZ79_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">VTC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_16540</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064149.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16540"/>
    <dbReference type="EnsemblBacteria" id="KPL72080">
        <property type="protein sequence ID" value="KPL72080"/>
        <property type="gene ID" value="ADN00_16540"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.100.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018966">
        <property type="entry name" value="VTC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042267">
        <property type="entry name" value="VTC_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09359">
        <property type="entry name" value="VTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VTC" evidence="1">
        <location>
            <begin position="42"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="228" mass="26719" checksum="BE34C4E5183A2751" modified="2016-01-20" version="1">MFNMDIDSQRYEIKMVFENSHRFAVESWVRLHSRAFRTAFPTRRVNNLYFDTHSQDMFNDHIAGTFERRKLRFRWYGENFSPAFGQLELKHKQGMIGWKDSQMILKSLDFARCGWQEIYADLQSEATGVFSEALVISRPILINNYQRQYFISADGMIRLTLDYDLTAFDQSASPRPNTSFPIPTRDLLIIEFKAAPELARDLADVLAEFPLPVEAYSKYVELAGWIFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZI7</accession>
    <name>A0A0P6WZI7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_15490</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063938.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15490"/>
    <dbReference type="EnsemblBacteria" id="KPL72223">
        <property type="protein sequence ID" value="KPL72223"/>
        <property type="gene ID" value="ADN00_15490"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1390.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028979">
        <property type="entry name" value="Ser_kin/Pase_Hpr-like_N_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75138">
        <property type="entry name" value="SSF75138"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="112" mass="12067" checksum="17FE1B17CF4885E6" modified="2016-01-20" version="1">MNLQKMIDALSLKVLTTPKDFSSITPTSGYTSDLLSCVMTGAASKGVWVTLQAHMNIVAVAALLDLSAVIITEGAQPDPETIAKANEEEITLLWTKEPSYSVVGKLWEMGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X006</accession>
    <name>A0A0P6X006_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_12800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063413.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000027.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12800"/>
    <dbReference type="EnsemblBacteria" id="KPL75519">
        <property type="protein sequence ID" value="KPL75519"/>
        <property type="gene ID" value="ADN00_12800"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132756" description="FHA domain-containing protein" evidence="2">
        <location>
            <begin position="28"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="443"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="domain" description="FHA" evidence="3">
        <location>
            <begin position="547"/>
            <end position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL75519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="639" mass="70534" checksum="119A192861D7DC44" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X1L2</accession>
    <name>A0A0P6X1L2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_13325</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063515.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000031.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74821">
        <property type="protein sequence ID" value="KPL74821"/>
        <property type="gene ID" value="ADN00_13325"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL74821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="62" mass="7134" checksum="2983239D4CF27C4B" modified="2016-01-20" version="1">MPETNKCLYCEITSLEVPLIKLDFKGQELFVCPQHIPLLIHEPQKLIGKLPGAERMVPYQQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X1Y0</accession>
    <name>A0A0P6X1Y0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_11075</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063076.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76507">
        <property type="protein sequence ID" value="KPL76507"/>
        <property type="gene ID" value="ADN00_11075"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.911"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132782" evidence="2">
        <location>
            <begin position="25"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL76507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="324" mass="35035" checksum="C1A524123448FE55" modified="2016-01-20" version="1">MTKKSLLWMLALVLLLSACAPKPAQETDAQMATRVAQILTAQPTSTIDPVLALSLTPGLDIQPIEMATATLQVEPTLPPTATAMPTETPAPTETPVPTETPTITPTLPPTSTPPSTDPRSVLGSPSSTDSMDNNTKWNWPVGSSEFASNEFKDGHMNLIGKAEIETDGPTGWILANTQTATNMYVEATYKTTACDGRDAYGIIFRVPVLSEADRGYIYEISCEGEFRLWKWDGKDGTSGKYTSLIAWQKPKGSAEGAINIGDNATNRLGVLVKDDLITVYVNGFKLGEARDGQFVAGNFGLVINPQKTEKFTVQIDEMSYWLNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X242</accession>
    <name>A0A0P6X242_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_14535</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000035">
        <property type="protein sequence ID" value="KPL73558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063756.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000035.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14535"/>
    <dbReference type="EnsemblBacteria" id="KPL73558">
        <property type="protein sequence ID" value="KPL73558"/>
        <property type="gene ID" value="ADN00_14535"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2073"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011697">
        <property type="entry name" value="Peptidase_C26"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044668">
        <property type="entry name" value="PuuD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43235">
        <property type="entry name" value="PTHR43235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07722">
        <property type="entry name" value="Peptidase_C26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL73558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="242" mass="25530" checksum="EB85E62F534249D7" modified="2016-01-20" version="1">MNPTPLIGLTVYRKSDGNGHWTQSLADAYGRAVIRAGAMPVLLPTQAGLDAAVLMERLDGLLLTGGGDMHPEVYGLRPHARVGSVDLLRDQIEVALVHAALQAGKPLLGICRGAQVLNVALGGDLFTDIADQTQSPIRHDCYDDLPRDHLAHGLRVLPGSRLHAALGVSETQVNSLHHQAVDRLGEGLKAVAWSPDGLVEGVEMDGEGFVVGAQWHPECLPEAQAMQALFAAFVNAAAQSGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X2I0</accession>
    <name>A0A0P6X2I0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_14765</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000035">
        <property type="protein sequence ID" value="KPL73598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063799.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000035.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL73598">
        <property type="protein sequence ID" value="KPL73598"/>
        <property type="gene ID" value="ADN00_14765"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="189"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="221"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="253"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="11"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="184"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL73598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="316" mass="34145" checksum="F8345477ED11BC66" modified="2016-01-20" version="1">MMIKRTSRTAAVALAFFVTFLWSTSWVLIKIGLLEIPPLLFAGLRYALAFAALLLVSLLSGQAAREWKGLTRREWGRLAVLGLVFYALTQGSSVMAQKYLPSASVSLMLNFTTPLVACLGIFWLNERLTRRQWLGITIFLAGGLLYFLPLETHSALPLGWAAAGVAVGGNTLAAVLGRSVNREQSLSPLSVTTLSMGVGALALLAAGAVWETLPAIRWQNWVIIAWLALVNGALAFTLWNHTQRHLAAAESSLINNTMLIQITLLTWLFLGEAVTTKEALGLGLAVLGMVVMQARVARRLEPPAPLVDDKEEGGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X4S4</accession>
    <name>A0A0P6X4S4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5 family acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_07860</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000020">
        <property type="protein sequence ID" value="KPL78088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062445.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000020.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78088">
        <property type="protein sequence ID" value="KPL78088"/>
        <property type="gene ID" value="ADN00_07860"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2866"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13508">
        <property type="entry name" value="Acetyltransf_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="141" mass="15772" checksum="5A06AE0FED6EEF8F" modified="2016-01-20" version="1">MELLLLADPSEDKIRSYLSSSKCFVASIDGDVVGACVVQPRGTDTHELMSIAVHPAHQKSGYGTALLKWVIDFFRIAGARQLEVGTGTFGYQLAFYQRQGFRVTSIDHDFFVKNYPEPIFEDGIQLFDMLRLTLKYSGNDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5C8</accession>
    <name>A0A0P6X5C8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_07225</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062309.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07225"/>
    <dbReference type="EnsemblBacteria" id="KPL78253">
        <property type="protein sequence ID" value="KPL78253"/>
        <property type="gene ID" value="ADN00_07225"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3265"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000175">
        <property type="entry name" value="Na/ntran_symport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037272">
        <property type="entry name" value="SNS_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00209">
        <property type="entry name" value="SNF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00176">
        <property type="entry name" value="NANEUSMPORT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161070">
        <property type="entry name" value="SSF161070"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50267">
        <property type="entry name" value="NA_NEUROTRAN_SYMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0769">Symport</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="105"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="165"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="194"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="232"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="275"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="322"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="361"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="404"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="443"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL78253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="468" mass="50077" checksum="E5A25B0A7093D46A" modified="2016-01-20" version="1">MELEHELESGKAKDAAASGGKQRDGFTTALGVIAATLGSAVGLGNIWKFPSITGQNGGAAFIIVYLISTLLVGLPVMITEQMLGRKARKDAISTLRELAPKKQPWWLAGAAGVLAAFLIMAFYTEVAGWVFAYIYKSVVGGFLSTDPAVTSQAFVDLITNPMQSLLWQWVVLVVIGAILMMGVSKGIEATTKRLMPILFLLLVAIGIRSLTLEGAGEGLRFLLQPDFSKVTWTTVLVAMGLAFFKLSTGMGTMITYGSYFREEQNIPGTATKVMLADLLVSMLAGIAIFPAVFAFGFEVDAGPSLLFITIPAVFASMPLGNIFMVLFFILAGIAATGAMLSLLEVPVAFINEKMHISRPVATVITVVLLALIGSTAALSSSTLADVKVFGFTFFDLFDYTTSNILLPVGGLFIALFAGWVWGKDRIVDALTNSGALKNEWVVKAFYVVIKFVTPVLLILVLLRGLSII</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5V8</accession>
    <name>A0A0P6X5V8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_09380</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77326">
        <property type="protein sequence ID" value="KPL77326"/>
        <property type="gene ID" value="ADN00_09380"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132877" evidence="2">
        <location>
            <begin position="26"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="28"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="248" mass="24666" checksum="BB0533B427E822D4" modified="2016-01-20" version="1">MKNKFLIFIMILIIGLLAACGPSVAASEPASGESAAPASPSTPAPAETAGADSQAAGGMNMEINDKLAAGTLLLEGTDLAVTQQQAQTLILLWQGVQSLSASDSTAPAELEAIYQQIQTAMTSEQLTAIEAMEIDPASLHETLTGLGLQMGRMGNPAGGEATGANAAEGGFPPGGMEPGMMGGGPGGGAGGGPGGGMGLEGQPPAQGTPSSEMATAIAERQAAGGFDLNAMYIRPLIQLLEQKTSDAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7D3</accession>
    <name>A0A0P6X7D3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable transcriptional regulatory protein ADN00_08160</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_08160</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the TACO1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062494.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08160"/>
    <dbReference type="EnsemblBacteria" id="KPL77847">
        <property type="protein sequence ID" value="KPL77847"/>
        <property type="gene ID" value="ADN00_08160"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.633"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.980">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00693">
        <property type="entry name" value="Transcrip_reg_TACO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017856">
        <property type="entry name" value="Integrase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002876">
        <property type="entry name" value="Transcrip_reg_TACO1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026564">
        <property type="entry name" value="Transcrip_reg_TACO1-like_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029072">
        <property type="entry name" value="YebC-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12532">
        <property type="entry name" value="PTHR12532"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01709">
        <property type="entry name" value="Transcrip_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75625">
        <property type="entry name" value="SSF75625"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01033">
        <property type="entry name" value="TIGR01033"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 4" id="KW-0805">Transcription regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL77847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="251" mass="27739" checksum="9E073902B2D0BCB7" modified="2016-01-20" version="1">MSGHSKWSTIKRKKGAADAKRGQIFTKLAREIVMAAREGGGDPNANFRLRLAVDKARLQNMPKDSIDRAIKRGTGESKDGETFEQITYEGYGPNAVALMIECFTENRNRTVAELRHVLSRSGGSLGESGSVAWQFDRVSFFEIPAEGVDFDKIFEIAVEGGADDVTMEDDLIEVIAPVESFKALSILLDKQGIKFNEAGLKMVPKQELTLGVEDTLQVMRTIEAVEDLDDVQNVYSNMRISEEAMAALEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="40" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7J1</accession>
    <name>A0A0P6X7J1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Bifunctional protein FolD</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="8">Methylenetetrahydrofolate dehydrogenase</fullName>
                <ecNumber evidence="8">1.5.1.5</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="8">Methenyltetrahydrofolate cyclohydrolase</fullName>
                <ecNumber evidence="8">3.5.4.9</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="8" type="primary">folD</name>
        <name evidence="11" type="ORF">ADN00_03680</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10-methenyltetrahydrofolate to 10-formyltetrahydrofolate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + NADP(+) = 5,10-methenyltetrahydrofolate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:22812"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57455"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.5.1.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>5,10-methenyltetrahydrofolate + H2O = (6S)-10-formyltetrahydrofolate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:57455"/>
            <dbReference type="EC" id="3.5.4.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the tetrahydrofolate dehydrogenase/cyclohydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.5" evidence="8"/>
    <dbReference type="EC" id="3.5.4.9" evidence="8"/>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061613.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03680"/>
    <dbReference type="EnsemblBacteria" id="KPL79003">
        <property type="protein sequence ID" value="KPL79003"/>
        <property type="gene ID" value="ADN00_03680"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.88"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004477">
        <property type="term" value="F:methenyltetrahydrofolate cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004488">
        <property type="term" value="F:methylenetetrahydrofolate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006164">
        <property type="term" value="P:purine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01080">
        <property type="entry name" value="NAD_bind_m-THF_DH_Cyclohyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01576">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000672">
        <property type="entry name" value="THF_DH/CycHdrlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020630">
        <property type="entry name" value="THF_DH/CycHdrlase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020867">
        <property type="entry name" value="THF_DH/CycHdrlase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020631">
        <property type="entry name" value="THF_DH/CycHdrlase_NAD-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00763">
        <property type="entry name" value="THF_DHG_CYH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02882">
        <property type="entry name" value="THF_DHG_CYH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00085">
        <property type="entry name" value="THFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00767">
        <property type="entry name" value="THF_DHG_CYH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="3 8 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 8" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="4 8" id="KW-0521">NADP</keyword>
    <keyword evidence="1 8" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="5 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 8" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="THF_DHG_CYH" evidence="9">
        <location>
            <begin position="6"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="THF_DHG_CYH_C" evidence="10">
        <location>
            <begin position="124"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="168"/>
            <end position="170"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL79003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="293" mass="31096" checksum="3DD19ED06CAF1A9B" modified="2016-01-20" version="1">MTAKIIDGKAVAAEVRAEVAAVVAQRVEAGKSRPGLATVLVGENPASQVYVRMKQKACAEAGIESFGYNLPEDTSQEDLEKLVRELNADERVNGILVQLPLPKHLDEERVLAAISLDKDVDGFHPVNIGRLAQKGRKPQFIPCTPAGCMLLLRKNLDSLEGVNAVVLGRSNIVGMPVALLLVEANATVTICHSRTKNLPDVVRQADVLVAAVGRPEMVRGDWIKPGAVVIDVGVNRIDDPSAKNGTRLVGDVAYDEAVEVAGAITPVPGGVGPMTIAMLLQNTLKAAELSDKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X836</accession>
    <name>A0A0P6X836_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Elongation factor G</fullName>
            <shortName evidence="6">EF-G</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">fusA</name>
        <name evidence="8" type="ORF">ADN00_06865</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the GTP-dependent ribosomal translocation step during translation elongation. During this step, the ribosome changes from the pre-translocational (PRE) to the post-translocational (POST) state as the newly formed A-site-bound peptidyl-tRNA and P-site-bound deacylated tRNA move to the P and E sites, respectively. Catalyzes the coordinated movement of the two tRNA molecules, the mRNA and conformational changes in the ribosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062243.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06865"/>
    <dbReference type="EnsemblBacteria" id="KPL78204">
        <property type="protein sequence ID" value="KPL78204"/>
        <property type="gene ID" value="ADN00_06865"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3189"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16262">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01434">
        <property type="entry name" value="EFG_mtEFG1_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03713">
        <property type="entry name" value="EFG_mtEFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00054_B">
        <property type="entry name" value="EF_G_EF_2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009022">
        <property type="entry name" value="EFG_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035649">
        <property type="entry name" value="EFG_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004540">
        <property type="entry name" value="Transl_elong_EFG/EF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00484">
        <property type="entry name" value="EF-G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6 8" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="5 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="7">
        <location>
            <begin position="8"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="17"/>
            <end position="24"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="81"/>
            <end position="85"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="135"/>
            <end position="138"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL78204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="690" mass="76186" checksum="68A7D6A4D9B35D56" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X856</accession>
    <name>A0A0P6X856_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acyl-CoA hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_16750</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064199.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16750"/>
    <dbReference type="EnsemblBacteria" id="KPL71357">
        <property type="protein sequence ID" value="KPL71357"/>
        <property type="gene ID" value="ADN00_16750"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.408"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033120">
        <property type="entry name" value="HOTDOG_ACOT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006683">
        <property type="entry name" value="Thioestr_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03061">
        <property type="entry name" value="4HBT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51770">
        <property type="entry name" value="HOTDOG_ACOT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HotDog ACOT-type" evidence="2">
        <location>
            <begin position="2"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51770"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL71357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="138" mass="15355" checksum="CC9028ACD7E8D46F" modified="2016-01-20" version="1">MAFTLFTTHRLIKSEDLNHHGTLYAGRSAEWFVESGFVAAASLLPPENIVCLKIHGMTFRQPANPGEIPVFQSRIVFAGRSSLVAHVRVRVREKELVSGFITFIHVDQQGNPQPHGIVLQADTDEEKQIAEAAKNLPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X8R5</accession>
    <name>A0A0P6X8R5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_03120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000014">
        <property type="protein sequence ID" value="KPL79332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061501.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000014.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79332">
        <property type="protein sequence ID" value="KPL79332"/>
        <property type="gene ID" value="ADN00_03120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="199" mass="21005" checksum="DAD403350DD8478A" modified="2016-01-20" version="1">MKSPVSTAVAIAVGLIVLLGFFIPVAVLQNLREVLVGWAAILAGVAGLVAILNLVSAHWRKLTSAGKRDVYSLALLLAFVVTLAAGLWLTPANADYQRVVTAIQAPVEMSLLALLAFSLAYASLRLLQRRRDLMSVIFVISAVVFLFLFSGFLPAAGNVFGFLQRLPMAGARGILLGVAAGSVMTGLRILLGADRPYSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X903</accession>
    <name>A0A0P6X903_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Histidine kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_11830</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063223.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76039">
        <property type="protein sequence ID" value="KPL76039"/>
        <property type="gene ID" value="ADN00_11830"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3842"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037257">
        <property type="entry name" value="T2SS_E_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160246">
        <property type="entry name" value="SSF160246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="132"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="91"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL76039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="360" mass="40285" checksum="D275C58336131A19" modified="2016-01-20" version="1">MAKVASTDNHENPVLPVRTLTPEILVPRLGDYLVERGILSQQALKDALIKQSQLTSPNQPPPLLGNILIDLGYIDRATLDEIITEQILQLRSALQAANQSLERRVQERTAELEMALKKVSELSQLKSNFIANISHELRTPLTHIIGYIELLISRDLGPMTEDQEQATFIMKRSSERLKHLIEDLILFSNTEGGQVHLEIETFSINLLFEELRRQILAKRRDTSMEIEVNCPEDLQPVRADQEKILWVLLQLVDNAIKFNKPGGKVTIAAENDGSFVRLSVTDTGIGIPPDKLEEIFEPFHQLDSSSTRKAGGTGLGLNLARKIVEAHGSILSVYSEPGEGSRFEFTIISSRPFSNHYPAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X911</accession>
    <name>A0A0P6X911_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_02805</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000013">
        <property type="protein sequence ID" value="KPL79405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061471.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000013.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02805"/>
    <dbReference type="EnsemblBacteria" id="KPL79405">
        <property type="protein sequence ID" value="KPL79405"/>
        <property type="gene ID" value="ADN00_02805"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003749">
        <property type="entry name" value="ThiS/MoaD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02597">
        <property type="entry name" value="ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="SSF54285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="119" mass="13504" checksum="0E12DFA0E1EA7CA5" modified="2016-01-20" version="1">MTLDVWLYGNLARYAGDPNETTFANPHPRLPAGSTLSDLLNHLGMDTEERGITFINGELSAMPGMQPDLQHELKDGDRVALFHLRSMWPFQYRNGIKMLSEMQKTMESSPDMGIHHAYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9D2</accession>
    <name>A0A0P6X9D2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable 2-phosphosulfolactate phosphatase</fullName>
            <ecNumber evidence="3">3.1.3.71</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_05465</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(2R)-O-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:23416"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15597"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58738"/>
            <dbReference type="EC" id="3.1.3.71"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ComB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.71" evidence="3"/>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78697.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061964.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05465"/>
    <dbReference type="EnsemblBacteria" id="KPL78697">
        <property type="protein sequence ID" value="KPL78697"/>
        <property type="gene ID" value="ADN00_05465"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050532">
        <property type="term" value="F:2-phosphosulfolactate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005238">
        <property type="entry name" value="ComB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036702">
        <property type="entry name" value="ComB-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37311">
        <property type="entry name" value="PTHR37311"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04029">
        <property type="entry name" value="2-ph_phosp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142823">
        <property type="entry name" value="SSF142823"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00033711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL78697.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="230" mass="25121" checksum="415F6CE0001D0CC8" modified="2016-01-20" version="1">MRYKYWSLDDCHHASGVVVVIDVVRAFTCAAVVLAGGAQRDYLVSGVEEALALRQRLPNAVVMGEIEGIKVPEFDFGNSPSQLSRINFQGKTVIQRTTSGTQGVVRSRQAEKIFAASFCVAGATARAIRALKPAEVNFVSTGIRDDGRGDEDVALADYLAALLSDKQPDPRPYLERVKNSLVAGLFTNPDDPDFPSADIPLTMDLDRYDFAMPVTWEEGIAFIDIHSRQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9N1</accession>
    <name>A0A0P6X9N1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Radical SAM protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_10080</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062875.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10080"/>
    <dbReference type="EnsemblBacteria" id="KPL76932">
        <property type="protein sequence ID" value="KPL76932"/>
        <property type="gene ID" value="ADN00_10080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040084">
        <property type="entry name" value="GTPase_Obg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01083">
        <property type="entry name" value="Uncharacterised_Radical_SAM_Su"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="6">
        <location>
            <begin position="12"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL76932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="331" mass="36989" checksum="4BF5E00042106982" modified="2016-01-20" version="1">MKYVFGPVPSRRLGQSLGIDPIPLKTCNWNCVYCQLGRTRPLVNERKEFFPADEILSEVKQALEAHQPDGIDWVTFVGSGETTLYSRLGYLIRQVKQMTPLPVAVITNGSLLYQPEVRQELAAADAVLPTLDAGNAEVYRKINRPHPDITYDRIQQGLISFREEYRGKLWIEVMLVQGLNDTEEALQEIEQVLIQIQPDEVHILQPTRLPVEPWVKPPSEEGLLRARAILGKTANVIAPASGSFDLSGNENLVDSIVGIITRHPMRESELIEALTRWSPADVKGTLKALEESGRAQIVTRYGVHFWSAAPARYPVNGQNETVNSIESSTES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9X2</accession>
    <name>A0A0P6X9X2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thioredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_11250</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thioredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063110.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11250"/>
    <dbReference type="EnsemblBacteria" id="KPL76533">
        <property type="protein sequence ID" value="KPL76533"/>
        <property type="gene ID" value="ADN00_11250"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005746">
        <property type="entry name" value="Thioredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000077">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="3">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="2">
        <location>
            <begin position="32"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000077-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL76533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="108" mass="12319" checksum="F0ABE81C9951E32F" modified="2016-01-20" version="1">MSELLSLNDSTFEKTVLQSAQPALIEFGAVWCAPCKRQEPILVELSKTWSDQCQFFKVDVDESTNLTMQFQVMSVPTMVLIVDGQEVERFTGLQNREKLVEKVEPYLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAB8</accession>
    <name>A0A0P6XAB8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">ADN00_03865</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="3">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061649.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03865"/>
    <dbReference type="EnsemblBacteria" id="KPL79036">
        <property type="protein sequence ID" value="KPL79036"/>
        <property type="gene ID" value="ADN00_03865"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00196"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000009">
        <property type="term" value="F:alpha-1,6-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004376">
        <property type="term" value="F:glycolipid mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007315">
        <property type="entry name" value="PIG-V/Gpi18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12468">
        <property type="entry name" value="PTHR12468"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04188">
        <property type="entry name" value="Mannosyl_trans2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="9"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="102"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="132"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="170"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="208"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="292"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="316"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="344"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="390"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL79036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="413" mass="45869" checksum="1FA22A67AED4A955" modified="2016-01-20" version="1">MKKNKENDLILLAAIWALWSLLVIGYQAVADWRLELKRPDSVLMWTANETGKNSQDDKAYLVEPFLNHQVSWDSEFYLSMATAGYDDPLVRTIKDPQNKGELLSMSYAFFPLYGWVMRVARVPLLALGLTPIVASTLAGVLVSLLGTLGAMIALYDLAQPLLEREGSLRAVYYMLIFPSAFFLAQVYTEGLFMGLSFGCMALARRDKWLPAGLLAAAATLTRPLGGLVVIPLAYRWWQAAPWNDETRDQPVWEMAVKSVGVALPVIAFLAWRASELGRNFFILEDQFFGRHFLAIGATISAWVGAFESVLKGNSQAAVYYALEVGSLLLGLVACGLFFRREKDLALYSLAVILLSLFSGAAQGMARYVLAAPVIFLCLGQWGRSRVFDRVWTFASVLLFGLSAMLFSFDFWVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAH6</accession>
    <name>A0A0P6XAH6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_04455</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061751.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04455"/>
    <dbReference type="EnsemblBacteria" id="KPL79118">
        <property type="protein sequence ID" value="KPL79118"/>
        <property type="gene ID" value="ADN00_04455"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="250"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL79118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="317" mass="35500" checksum="5F4D4E9325092DAA" modified="2016-01-20" version="1">MSNLQDAIRQEAARLLAEKIVDVVIGFESESTPLKPQPAFIRRADEAEKLVFNGFCQNNLATFLNRYPKTTRIGLVARGCESRAAHALLVEHQRSRESLYLIGVPCQGIVDWRKVELRAGENILSAQEDDGVVRVMTRQGEVSLPREELLHDSCARCLHPNPVNADVMLGEPLSEGDPARARQPIDAFEALSGAERYAFFTHEAERCIRCYACREACPMCYCAECFVDHTAPRWAESTTAASGTQAWHLVRAFHQAGRCVSCGACERACPMDIKMTYLTDKLNEDMRALYGFEPGMDDTRQPPFAAFSLDDKDRFMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAJ8</accession>
    <name>A0A0P6XAJ8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Glycine/betaine ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_08900</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08900"/>
    <dbReference type="EnsemblBacteria" id="KPL77252">
        <property type="protein sequence ID" value="KPL77252"/>
        <property type="gene ID" value="ADN00_08900"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="27"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="137"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="176"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="23"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL77252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="214" mass="22807" checksum="7DBAE0398F3BD873" modified="2016-01-20" version="1">MMDSLQGAYQYILENQAFFWQSVRQHLALSFSALGISLLVALPAGIWIAKRAKIAQAVINFFTAFRVIPSLAILFLALPYLGLGFVPALVALSILAFPPVLINTYTGLRGVDPFLIEAAAGMGMTPQQVLRKVELPLAVPAIVTGIRIASVEVISSASLASFIGGGGLGDFVTRGFALYSVSVMLVGAIPIALLALSSEFFWSIFLKVYPSIGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAX0</accession>
    <name>A0A0P6XAX0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_09930</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062845.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09930"/>
    <dbReference type="EnsemblBacteria" id="KPL76908">
        <property type="protein sequence ID" value="KPL76908"/>
        <property type="gene ID" value="ADN00_09930"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011747">
        <property type="entry name" value="CHP02241"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010667">
        <property type="entry name" value="Phage_T4_Gp19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38009">
        <property type="entry name" value="PTHR38009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06841">
        <property type="entry name" value="Phage_T4_gp19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02241">
        <property type="entry name" value="TIGR02241"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="148" mass="16550" checksum="CFADBD95377B0118" modified="2016-01-20" version="1">MPTREDPLVSFKFGLEIEGKLTGFFTQVSGIGSESEVIQHKVVNSETGETIMQQIPGRLTWTPVTLKRGVTSSMDIWEWRQQVVEGKIGEARTNCSIVAYAQDNTEIARWNFENAWPSKVVGPEMDAGSTNYMIEDVTIVHEGVERVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBC0</accession>
    <name>A0A0P6XBC0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peptide ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_10825</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063012.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10825"/>
    <dbReference type="EnsemblBacteria" id="KPL77045">
        <property type="protein sequence ID" value="KPL77045"/>
        <property type="gene ID" value="ADN00_10825"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2643"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="10"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="54"/>
            <end position="61"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL77045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="328" mass="36396" checksum="31C168A7574429A7" modified="2016-01-20" version="1">MTSNSKEVLLKVNNLVKHFPITQGIVIQRQVGAVHAVDGVSFDVYKGETLGLVGESGCGKSTTGRTILQLYRPTSGEVLFEGRNLVDLKGEELRKTRRRMQMIFQDPYASLNPRMTVGEIIGEPMLIHRTHTAQEIQDRVADLLALVGLNPAFANRYPHEFSGGQRQRIGVARALALDPSLIVCDEPISALDVSIQAQVVNLLEDLQQELGLTYLFIAHDLSMVRHISDRVAVMYLGIIVELADRDELYNNPLHPYTQALLSAVPIPDPVAESKRQRIILQGDVPSPVNPPSGCRFRTRCPLAVEVCAQKKPEFREIKPGHFTACHLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBD8</accession>
    <name>A0A0P6XBD8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">UDP-N-acetyl-D-mannosamine dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_01930</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000007">
        <property type="protein sequence ID" value="KPL80054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061277.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000007.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01930"/>
    <dbReference type="EnsemblBacteria" id="KPL80054">
        <property type="protein sequence ID" value="KPL80054"/>
        <property type="gene ID" value="ADN00_01930"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2312"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017476">
        <property type="entry name" value="UDP-Glc/GDP-Man"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014027">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036220">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014026">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001732">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028359">
        <property type="entry name" value="UDP_ManNAc/GlcNAc_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00984">
        <property type="entry name" value="UDPG_MGDP_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03720">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03721">
        <property type="entry name" value="UDPG_MGDP_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500136">
        <property type="entry name" value="UDP_ManNAc_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000124">
        <property type="entry name" value="UDPglc_GDPman_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00984">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52413">
        <property type="entry name" value="SSF52413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03026">
        <property type="entry name" value="NDP-sugDHase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDPG_MGDP_dh_C" evidence="4">
        <location>
            <begin position="310"/>
            <end position="407"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL80054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="424" mass="46102" checksum="1A4506C157DA996E" modified="2016-01-20" version="1">MQFEKICILGLGYIGLPSASTFATHGLQVVGVDVDQRVVSGLKNGEVHLFEPGLRTLVQAAIKSGKLTISSQPEEADAFIIAVPTPFLEDKRADMRFVISATEAIVPVLRRGNLVVLESTSPPRTTVDLVAPILERSGLKAGEDFFLAYSPERVLPGQILKELIENARVIGGIDAASAEAGRDLYRVFVRGDIVLTDSTTAEMVKIMENTYRDVNIAIANEFSRLADRFGVDVWEAIEIANRHPRVNILRPGPGVGGHCISVDPWFLVEAAPDLTPLIRTAREVNDSQPHFVLKLAQKLLGGNLSGRTVAVLGLTYKPDVDDFRESPAVEAALLLQAAGARVRAHDPFQPKQPIDGLDLCDLDEALRGADALVVLVAHSEYRQLNPQALAAKTTARSVLDAVHIFDESAWREAGFNLQRLGRAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XC99</accession>
    <name>A0A0P6XC99_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_08270</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062514.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08270"/>
    <dbReference type="EnsemblBacteria" id="KPL77864">
        <property type="protein sequence ID" value="KPL77864"/>
        <property type="gene ID" value="ADN00_08270"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.656"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005976">
        <property type="term" value="P:polysaccharide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001538">
        <property type="entry name" value="Man6P_isomerase-2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01050">
        <property type="entry name" value="MannoseP_isomer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NTP_transferase" evidence="1">
        <location>
            <begin position="7"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="MannoseP_isomer" evidence="2">
        <location>
            <begin position="322"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="363" mass="40032" checksum="4F3534F395FFBF71" modified="2016-01-20" version="1">MLEHTYAVIMAGGGGTRLWPLSRRANPKQMLRLGAERTLFQQAVDRLMGLIPVERIWVVTVAEQALELGKQCPDIPEQNFLLEPMPKGTASVVGFAAAALSKVDANASMIILTADHFIQNISVFHACLKSAVKVAQAGFLVTLGIEPTYPATGYGYIQQGASLDIESEVKAFQVVRFKEKPNLETAQKMIESGDHAWNSGMFIWRVDRILEEFASSMPGLYEKLMEIQAAWGGKDQKMVVDSVWPTLHPETIDYGIMEKASQVAVLPAHQLGWDDVGSWDSLFDVLEPDEQGNIVLEARHIGMGTKGSLICGETSNRMIVTLGVENMIVVDTGDAVLICPRGNSQRVRDLVTYLKEQGLERYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XCH0</accession>
    <name>A0A0P6XCH0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_01710</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061231.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01710"/>
    <dbReference type="EnsemblBacteria" id="KPL80584">
        <property type="protein sequence ID" value="KPL80584"/>
        <property type="gene ID" value="ADN00_01710"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032688">
        <property type="entry name" value="ABC2_membrane_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12679">
        <property type="entry name" value="ABC2_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="90"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="137"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="182"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="211"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="236"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL80584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="276" mass="30292" checksum="9CB4184371AF6C95" modified="2016-01-20" version="1">MNPRILLAIAKKDLLEVRQNKAAWMPMIIVPLVFIIVFPLIILVLPQLSGQAAEQMINDPDMAMMFERLPGIIADKIAGMNPMQSIVVMMLGYFFAPMFLIFPLMFSTTVAAESFAGERERKTMEALLYTPVSDTELFFGKMLAGLIPGIFISWASFLLYSVVLNAAGWPLFGELWFPLATWYPLIFWVTPALAVMGVGLTVLISSKVQTFMGAYQASASLVILVVGLMLGQFAGVVYLSVGVGMLIGLLAWIIAGVMVFVSFQNFNRAKLLVSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XCX5</accession>
    <name>A0A0P6XCX5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Inositol-1-monophosphatase</fullName>
            <ecNumber evidence="6">3.1.3.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_01375</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>a myo-inositol phosphate + H2O = myo-inositol + phosphate</text>
            <dbReference type="Rhea" id="RHEA:24056"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17268"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:84139"/>
            <dbReference type="EC" id="3.1.3.25"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the inositol monophosphatase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.25" evidence="6"/>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061169.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01375"/>
    <dbReference type="EnsemblBacteria" id="KPL80526">
        <property type="protein sequence ID" value="KPL80526"/>
        <property type="gene ID" value="ADN00_01375"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1027"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008934">
        <property type="term" value="F:inositol monophosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052832">
        <property type="term" value="F:inositol monophosphate 3-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052833">
        <property type="term" value="F:inositol monophosphate 4-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046855">
        <property type="term" value="P:inositol phosphate dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046854">
        <property type="term" value="P:phosphatidylinositol phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01639">
        <property type="entry name" value="IMPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033942">
        <property type="entry name" value="IMPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020583">
        <property type="entry name" value="Inositol_monoP_metal-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000760">
        <property type="entry name" value="Inositol_monophosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020550">
        <property type="entry name" value="Inositol_monophosphatase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022337">
        <property type="entry name" value="Inositol_monophosphatase_SuhB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00459">
        <property type="entry name" value="Inositol_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00377">
        <property type="entry name" value="IMPHPHTASES"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01959">
        <property type="entry name" value="SBIMPHPHTASE"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00629">
        <property type="entry name" value="IMP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00630">
        <property type="entry name" value="IMP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL80526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="263" mass="29074" checksum="3D35148FD2288460" modified="2016-01-20" version="1">MTQPQLLDLKILARQAGAILREGFGRQHQVDYKSLTDIVTEIDRQSEEFLTGQVLSRFPGDTIQGEEGGLTQGENGRVWHIDPLDGTVNYAHGVPIFSVSLACAWDGAVQLGVVYDPMRDEMFSARRGQGAWLNDAPIHVSQTEELVSALLVTGFPYTIREQEATNLDHFTHFCMRARSVRRLGSAALDLCYVAAGRLDGYWEIGIHSWDVAAGGLIVEEAGGRVTTLRGDEAYFKPPYDLACANPRLQPQMLDVLRLGLTRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDJ1</accession>
    <name>A0A0P6XDJ1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_00365</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060970.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00365"/>
    <dbReference type="EnsemblBacteria" id="KPL81032">
        <property type="protein sequence ID" value="KPL81032"/>
        <property type="gene ID" value="ADN00_00365"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="11"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="84"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="151"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="225"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL81032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="280" mass="31680" checksum="FDA4C394125AA75A" modified="2016-01-20" version="1">MTTSKIVENWMTQPVVSVDPYTRLDDAKQLMNTKSIRTLPVTNEGKLVGIVTRRDLLRYDPSAAMKSHWTEYSGLENETVDHIMSRKVTTIRSNATVGQAARVMYENKFSGLPVTDTSRQMIGIITSTDMFRFILENSDYVNSFYKTSSLMTSLVETIAPYETLFEAHRLMGIMRIRALPVVDDHETLVGIITRTDVLSADPSAFMKNRQDLSRKILSTPISYIMTSKPITINPDTPVSTAAELMMTYKIHSLPVLNEENRLAGIITDSDLFHMILQKFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XEK4</accession>
    <name>A0A0P6XEK4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_07890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000020">
        <property type="protein sequence ID" value="KPL78087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062444.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000020.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78087">
        <property type="protein sequence ID" value="KPL78087"/>
        <property type="gene ID" value="ADN00_07890"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="285" mass="32619" checksum="DC12878F886C5298" modified="2016-01-20" version="1">MESLNNILDNREIAIIIWLGVFFVWALSQKKIRKSFVKVFKTFAQKVIFISSILMVLYIGTMIYLLHRINLWNISYLSDTIIWILGVAFVLFVNISHAREDDYFRKAVVDNIKLVVFIEFITDLYVFNLWVELILVPVLALLGALLGAASARPEFKRVESLLAPIVGLIGVGFLAYAIYNMIVDFGAFLSMQNLLTLLMPLILTILFLPFVYVLAVYVVYDSIFMRIKKIVANPKLANYAKWQTLFAFHLNLKALNKWLRKVVVSKLESREAIKQAILSVKMSGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XEU6</accession>
    <name>A0A0P6XEU6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Adenosylcobinamide kinase</fullName>
            <ecNumber evidence="8">2.7.1.156</ecNumber>
            <ecNumber evidence="9">2.7.7.62</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Adenosylcobinamide-phosphate guanylyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">ADN00_05515</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes ATP-dependent phosphorylation of adenosylcobinamide and addition of GMP to adenosylcobinamide phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenosylcob(III)inamide + ATP = adenosylcob(III)inamide phosphate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15769"/>
            <dbReference type="ChEBI" id="CHEBI:2480"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58502"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.156"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>adenosylcob(III)inamide + GTP = adenosylcob(III)inamide phosphate + GDP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:15765"/>
            <dbReference type="ChEBI" id="CHEBI:2480"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="ChEBI" id="CHEBI:58502"/>
            <dbReference type="EC" id="2.7.1.156"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>adenosylcob(III)inamide phosphate + GTP + H(+) = adenosylcob(III)inamide-GDP + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22712"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58502"/>
            <dbReference type="ChEBI" id="CHEBI:60487"/>
            <dbReference type="EC" id="2.7.7.62"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 5/7.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 6/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the CobU/CobP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.156" evidence="8"/>
    <dbReference type="EC" id="2.7.7.62" evidence="9"/>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78705.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061974.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05515"/>
    <dbReference type="EnsemblBacteria" id="KPL78705">
        <property type="protein sequence ID" value="KPL78705"/>
        <property type="gene ID" value="ADN00_05515"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1580"/>
    <dbReference type="UniPathway" id="UPA00148">
        <property type="reaction ID" value="UER00236"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043752">
        <property type="term" value="F:adenosylcobinamide kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008820">
        <property type="term" value="F:cobinamide phosphate guanylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00544">
        <property type="entry name" value="CobU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003203">
        <property type="entry name" value="Cobinamide_kinase/P_G-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34848">
        <property type="entry name" value="PTHR34848"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02283">
        <property type="entry name" value="CobU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006135">
        <property type="entry name" value="CobU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="17" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="12" id="KW-0418">Kinase</keyword>
    <keyword evidence="11 17" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AAA" evidence="18">
        <location>
            <begin position="2"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="active site" description="GMP-histidine intermediate" evidence="16">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <begin position="10"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <begin position="35"/>
            <end position="37"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <begin position="52"/>
            <end position="55"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00003889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00005159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00007490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00012016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00012523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00029570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00030571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR006135-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR006135-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KPL78705.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="185" mass="19802" checksum="D7F1F10CC91EF332" modified="2016-01-20" version="1">MTRHLTLILGGARSGKSTYAEKLAAGLQRPVIYIATATAGDAEMEERIASHRASRPADWATLEASAQVGRAVAQSPLSADVYLLDCVTLWVSNVILSLPEPYSVQQAQAAMDAELDDLLAQIEQRGGEWILVSNEVGLGLVPAYELGRLYRDTLGRANQRLAAAADRVIFMVAGLPMQVKPGSLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XF46</accession>
    <name>A0A0P6XF46_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_07270</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062317.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07270"/>
    <dbReference type="EnsemblBacteria" id="KPL78261">
        <property type="protein sequence ID" value="KPL78261"/>
        <property type="gene ID" value="ADN00_07270"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036748">
        <property type="entry name" value="MTH938-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64076">
        <property type="entry name" value="SSF64076"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="120" mass="13181" checksum="6221A5B208C49881" modified="2016-01-20" version="1">MKPKIDSAAFGEIVVGGTQYTHDIIIRLDGSIERRRKHLSKAVYGTSHLLSLAEAEFIYEQGAEQVLFGGGQFGKCRLSDDAIDYFKSKGCDVTMVPIGAAIELWNQMDGKVIGVFHLTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XFE8</accession>
    <name>A0A0P6XFE8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Lactate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_14515</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000035">
        <property type="protein sequence ID" value="KPL73555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063752.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000035.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14515"/>
    <dbReference type="EnsemblBacteria" id="KPL73555">
        <property type="protein sequence ID" value="KPL73555"/>
        <property type="gene ID" value="ADN00_14515"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2068"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1530.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043144">
        <property type="entry name" value="Mal/L-sulf/L-lact_DH-like_ah"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043143">
        <property type="entry name" value="Mal/L-sulf/L-lact_DH-like_NADP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036111">
        <property type="entry name" value="Mal/L-sulfo/L-lacto_DH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003767">
        <property type="entry name" value="Malate/L-lactate_DH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11091">
        <property type="entry name" value="PTHR11091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02615">
        <property type="entry name" value="Ldh_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89733">
        <property type="entry name" value="SSF89733"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL73555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="368" mass="39715" checksum="82B7CF14832CA3AB" modified="2016-01-20" version="1">MTETVKVLPVNVLQQFMQDVFVGLGVPADEAAISAQILIQSDLFGIESHGVGRLKMYYDRIKNGQHRPVTQFEIVKEAPATAVVDGHHGVGMVIGYKAMNLAIEKARVYGMGSVAVRNSTHFGIDGYYPLMAARAGMIGMSFTNARPSIAPTFGVQPMLGTNPIAFGCPTDEANPFLYDAATSITQRGKFETLERKGQPGKAGWVTDQQGNFLTDASEVLKGLTQDTAALLPLGGAGEDLGGHKGYGLATIVEILSASLQGGAFLHALTGITPDGGKTHFQLGHFFMAINVESFTDLDSFKKTTGDILRALRASRKAPDQPRIYTAGEKEFEKEIEVRQTGVAIVPKLQQDLLTMRDELGLTQYQFGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XG67</accession>
    <name>A0A0P6XG67_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_18620</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064545.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18620"/>
    <dbReference type="EnsemblBacteria" id="KPL70063">
        <property type="protein sequence ID" value="KPL70063"/>
        <property type="gene ID" value="ADN00_18620"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3033"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.90.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035328">
        <property type="entry name" value="DUF3048_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021416">
        <property type="entry name" value="DUF3048_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023158">
        <property type="entry name" value="YerB-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11258">
        <property type="entry name" value="DUF3048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17479">
        <property type="entry name" value="DUF3048_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159774">
        <property type="entry name" value="SSF159774"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133045" evidence="2">
        <location>
            <begin position="22"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3048" evidence="3">
        <location>
            <begin position="86"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3048_C" evidence="4">
        <location>
            <begin position="255"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL70063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="401" mass="43668" checksum="7C9E4DF8782B2DFF" modified="2016-01-20" version="1">MFKKTTIAAVLILLLLSACQAAGVGPKTDASGSDQDASVNASSTPFQPVTPAATNTPVPTSTPIPTPTATPIQVGPSGFSENTNPLTGLQVEDPAILNRRPLMIKVANFPREGRPHAGLSSADIVFDYYIGEGTNRFMAVYYGQDAEKIGPMRSGRLVDAQLTRLYQGVLGFVSADPNKVFPVLYNNLGLRAITQMGDSCPAICDDGQHTVISVFANSAAFSQYAANRGVDVARQNLDGMYFYSVAPSGQPGQQVTLKYNAYNFSQWRYDAERGQYLAWMETADVNNNISTVELTDRNTGQQLTRDNVIILFAPYNELAPTLHEIALWNNAQGKRAVLFRDGQMIEAIWKTPGTDQPIQFFTSDGNPLPLKPGTSWIMIAGENSLLAEQDTAQYELQFRLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGD8</accession>
    <name>A0A0P6XGD8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_05940</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SorC transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78773">
        <property type="protein sequence ID" value="KPL78773"/>
        <property type="gene ID" value="ADN00_05940"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007324">
        <property type="entry name" value="Sugar-bd_dom_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04198">
        <property type="entry name" value="Sugar-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r4" evidence="3">
        <location>
            <begin position="31"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar-bind" evidence="2">
        <location>
            <begin position="75"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL78773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="331" mass="36356" checksum="AC9E2B1ECE656ED0" modified="2016-01-20" version="1">MYICKLINPQGKTMFNQIDQAEYRLCVRVARLYYDSGFTQNEIGEKLGYSRVTIHRILNRAIELGIVEIKINAPQNQNFDLEQDLIVKFNLRDAVVVGDPEGDDSIYFALARGAADWLKRSLKSGMRVGLGLGRTISHLPIMFSTDNSIDCTFIEIVGGASDHSGGFAKYNITSKMAEIAGGKAEFLYAPNLVSNAEIQKALVNEPSISAALDRARHSDIVIQSIGTVDNSAILYVEKKITLEELKSLQIAGAVGDALGHYFNQNGEIVSTFLDNRIIGISLDDLKKIPWSVLVAGGEEKKTVIQAAMKGNFFNVLVTNADTAKYLLSQSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGV8</accession>
    <name>A0A0P6XGV8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_03625</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03625"/>
    <dbReference type="EnsemblBacteria" id="KPL78992">
        <property type="protein sequence ID" value="KPL78992"/>
        <property type="gene ID" value="ADN00_03625"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.77"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="234"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="268"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="7"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="318" mass="36077" checksum="21AE756B774B572F" modified="2016-01-20" version="1">MMQPTFSIIAPVFNERENLPALRERVSEVMNQTGEPWELILVDDGSKDGSTDIIRQMGKEDEHVRPVIFARNFGHQLAVTAGLDYSRGKAVVIIDSDLQDPPEVILDLIAKWREGYEVVYAVRAEREGETWFKMFTASLFYRIIYRITDVDIPLDTGDFRLLDRQVVNVMNSMRERHRFLRGMSAWVGFRQVGVAYKRRARMAGETKYPFKKMLRLALNAITGFSYFPLQVATYMGFISAGVSILAIPVVIIMRLMGDQAFLGQASTLISVLFLGGVQLISLGILGEYIGRIYDEVKGRPLYIVHDAPTNDSQPNQQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XIT0</accession>
    <name>A0A0P6XIT0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_02155</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000009">
        <property type="protein sequence ID" value="KPL79788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061319.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000009.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02155"/>
    <dbReference type="EnsemblBacteria" id="KPL79788">
        <property type="protein sequence ID" value="KPL79788"/>
        <property type="gene ID" value="ADN00_02155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004481">
        <property type="entry name" value="K/Na/Ca-exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10846">
        <property type="entry name" value="PTHR10846"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="36"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="170"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="201"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="235"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="276"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="303"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="Na_Ca_ex" evidence="6">
        <location>
            <begin position="3"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="Na_Ca_ex" evidence="6">
        <location>
            <begin position="177"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL79788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="330" mass="35344" checksum="EC1E2D90D794A83F" modified="2016-01-20" version="1">MIWVEFLFYSAIIVYSAIKLAEYGDVIAIRTRLGGMLIGIILMAGATSLPELLTTINAISQGVPNLAAGNMFGSNMFNMFILGAMGLINIRTRILRKVARRHALTGALTILMICFAIFFVLADLEIKIGWVGIDSIILLFTYIAALLIIQKDSHTAHEIAEAQEDDFEGIPSLAAGLLGFALSTALLIIVMPALVGTSAEIAEITGLGTGFVGTTLVAIVTSLPEMITTIAAVRLGVYDMAVGNLFGSNMFNMFSLGISDVIMTKGLFMSVISDDFIIVGMLGLIMTALGLVGNLAKLERKFIIFEFDALALIVTYILGMGLIYLRGIAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XJR2</accession>
    <name>A0A0P6XJR2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_11755</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063209.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76029">
        <property type="protein sequence ID" value="KPL76029"/>
        <property type="gene ID" value="ADN00_11755"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3827"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="5"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="41"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL76029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="250" mass="27605" checksum="6BC3FE1A4CA38B94" modified="2016-01-20" version="1">MKQVLQAQQVRKLYRLGDHSVNALAGVDFAVEQGEFVAIMGPSGSGKSTLLHLLGGLDKPSEGEVILAGNRLSELNDQAATLARRHHVGFVFQFFNLLPTLTARENILLPLLIDGKDTNGYEERLLTLLDLVGLSERQNHKPDQLSGGEQQRVAIARALITAPELVLADEPTGNLDTKTGRAIMQLLRRSCDEFSQTMVVVTHDPQAAIYADRVIFLRDGLVVQQIHLNPQEPLAVRLKMVMDEMEKLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XLE1</accession>
    <name>A0A0P6XLE1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF559 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10935</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10935"/>
    <dbReference type="EnsemblBacteria" id="KPL77062">
        <property type="protein sequence ID" value="KPL77062"/>
        <property type="gene ID" value="ADN00_10935"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007569">
        <property type="entry name" value="DUF559"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04480">
        <property type="entry name" value="DUF559"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF559" evidence="1">
        <location>
            <begin position="13"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="116" mass="13670" checksum="1ABB9B3BBB84F34E" modified="2016-01-20" version="1">MANLSKKQISMIHAREMRKLPTPAEDKLWQRIRHHQINNIHFRRQHPIGDYIVDFCAPARKLIIEIDGGFHAGQFDYDSERTAIFESKGYSVLRFRNAEVLENIEQVIQEIKKVVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XMR9</accession>
    <name>A0A0P6XMR9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nitroreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_11135</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063088.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11135"/>
    <dbReference type="EnsemblBacteria" id="KPL76517">
        <property type="protein sequence ID" value="KPL76517"/>
        <property type="gene ID" value="ADN00_11135"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.923"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.109.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029479">
        <property type="entry name" value="Nitroreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000415">
        <property type="entry name" value="Nitroreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020051">
        <property type="entry name" value="SagB-type_dehydrogenase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00881">
        <property type="entry name" value="Nitroreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55469">
        <property type="entry name" value="SSF55469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03605">
        <property type="entry name" value="antibiot_sagB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitroreductase" evidence="1">
        <location>
            <begin position="64"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="245" mass="27363" checksum="95BB6763EF2E43AD" modified="2016-01-20" version="1">MTDSTGKEFMRRTRYQNMGPSLQEQGAPQPALQLPCENALEIIALPAIDQIATPAMDVRQALGQRKTLRKYSEQSLSLDELAYLLWATQGVKSVKENAHTFRVVPSAGARHAFETYLLINRVEDLQPGLYRYLALDHTLARLPAPADLPASLSEASLKQSKIAYSAVTFLWVAVRERMVWRYNERGYRYLHLDAGHVCQNLCTAAETIDCGLCPIAAYDDDQVNALLGLDGEELFVIYMASLGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XNK8</accession>
    <name>A0A0P6XNK8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">VOC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09625</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062789.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76855">
        <property type="protein sequence ID" value="KPL76855"/>
        <property type="gene ID" value="ADN00_09625"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2381"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025870">
        <property type="entry name" value="Glyoxalase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12681">
        <property type="entry name" value="Glyoxalase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="159" mass="18513" checksum="312262EC44C960F6" modified="2016-01-20" version="1">MVTYIGPLMVVEDMARARGFYEDLLGQKVKFDFGENVQFEGGFSLHLKAHFQALLGGAETFPVCRRAHWGEIYFELDDLETLFQRLSNARVEFIHAIREQPWGQRVMRFYDPDGHIIEVGESLQAVVWRFYQQGLPIEQISEKSAMPRAFVEQVIRERS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XNM7</accession>
    <name>A0A0P6XNM7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">VOC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09835</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062827.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09835"/>
    <dbReference type="EnsemblBacteria" id="KPL76892">
        <property type="protein sequence ID" value="KPL76892"/>
        <property type="gene ID" value="ADN00_09835"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2425"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="4"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="140" mass="16130" checksum="E8C01150E87D43BE" modified="2016-01-20" version="1">MKQDIVHIALVVRDYDEALDFYLNKLNFELIEDTYQPEQDKRWVVIAPPGSRGTTLLLARASKAEQEPFIGNQAGGRVFLFLHTDDFWRDYEAMRAKGIHFVREPKQADYGTVAVFEDLYGTLWDLVQFNAGHPIARRVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-08-12" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XPN3</accession>
    <name>A0A0P6XPN3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Twitching motility protein PilT</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_14015</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ycf81 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74150">
        <property type="protein sequence ID" value="KPL74150"/>
        <property type="gene ID" value="ADN00_14015"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1902"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01938">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00670">
        <property type="entry name" value="PINc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="109"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="TRAM" evidence="3">
        <location>
            <begin position="293"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL74150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="359" mass="38980" checksum="31140361906120E9" modified="2016-01-20" version="1">MVRLIGMIIFSILGVYSGVYLGQLANVEPGTNTLSVEQYGVIIGMVGALVGLILTPFLTTRPIRALRQLLSRISAQNLFAALSGLVVGLIIAVLAAFPLSLLPKPLGSILPFVGVLLFGYLGVAVFMMRQHDLFSIFQSLNPRSGGSSSAGETADSKSNLADNRSILLDTSVIIDGRIADIARTGFIPGALLIPRFVLTELQYIADSPDSLRRQRGRRGMEVLSTLQKEPSIPVRLSDIDVEGVREVDDKLVILARQMRCPILTNDYNLNRIAELQGVTVLNVNELANAVKSVLLPGEILNIRVIQEGKESGQGVGYMDDGTMVVIENGREHMDREIEVVVTKVLQTAAGRMIFARPEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XPQ2</accession>
    <name>A0A0P6XPQ2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05185</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05185"/>
    <dbReference type="EnsemblBacteria" id="KPL78653">
        <property type="protein sequence ID" value="KPL78653"/>
        <property type="gene ID" value="ADN00_05185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="200"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="245"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="312"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="340"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="375"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="407"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="569"/>
            <end position="587"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="601" mass="67440" checksum="CA06C468800885A8" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XPY5</accession>
    <name>A0A0P6XPY5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_16725</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064194.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL71353">
        <property type="protein sequence ID" value="KPL71353"/>
        <property type="gene ID" value="ADN00_16725"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.403"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021247">
        <property type="entry name" value="DUF2785"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10978">
        <property type="entry name" value="DUF2785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL71353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="310" mass="34334" checksum="72E55C79E671540C" modified="2016-01-20" version="1">MLDIAELKEIVKRDFAAPQGRQAADLLAEVMEGLGSADSEQRETSLDVLWAWITRGMLSEDQLVALGEQMVNNLSVGLGEKDTDSVFLRAFSALIVGLVVEVDQERATGELACEPFLAREQVLDWLKRSMIWYRKEADLRGYVPAGKGWAHAAAHGADLLSDMACSRHLGSEERKAILGLSVERLLDPAGLPWLFNECERLAVAVYAALLRLELGEAELKTWLAPLTRAPGGVSWRSAFLDGARADYEEVNRARVNGKDFLRSLYFQVKLPARHQDANLVAARRAYLDEVLLPVLAWALLEVDGGSFFQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQ13</accession>
    <name>A0A0P6XQ13_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_09485</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062749.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09485"/>
    <dbReference type="EnsemblBacteria" id="KPL77340">
        <property type="protein sequence ID" value="KPL77340"/>
        <property type="gene ID" value="ADN00_09485"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4136"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004104">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="7"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA_C" evidence="2">
        <location>
            <begin position="138"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="368" mass="40379" checksum="0AEADFAF97E8DA6F" modified="2016-01-20" version="1">MKSEKITVGVIGVGQIGKLHLETYLSMPNVRVVGIAGRDPQRTEAVARQYNIPFWTTNYHALLENPNIQAVSVCLHNNLHMPVSVAALRAGKHVFCEKPIAGSYHDGLIMLETAAQQNRLLSIQLSDLFSKETKAAKVAIENGWLGAPYLAHSSGFRRRGRPFVDGYGSSDFVKKEIAGGGALYDLGVYHIANILYLLGNPRPLRMSGRTFQQTEMHQGRKNASHFNVEELAVGLVNLENNIALSVIEAWAMHLDHLESSYITGTMGGIRLNPFGLFRSLGDLDLNTTADLDSFDFRSKNVQETGDCFDGPQQHFIAAVEERIQPIPTAEIALNTMLILEGIYLSEHLGCEVTADLVKSNSQGNAIPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQ57</accession>
    <name>A0A0P6XQ57_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Zinc metallopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13840</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063631.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000032.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13840"/>
    <dbReference type="EnsemblBacteria" id="KPL74388">
        <property type="protein sequence ID" value="KPL74388"/>
        <property type="gene ID" value="ADN00_13840"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1344"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007395">
        <property type="entry name" value="Zn_peptidase_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36434">
        <property type="entry name" value="PTHR36434"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04298">
        <property type="entry name" value="Zn_peptidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="207"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="233" mass="25432" checksum="12E0039992433F08" modified="2016-01-20" version="1">MFGGYGLYILFSLPALLLGMWAQAKVRSAFSKYSRVRSNVGMSGAEVARAMLDSNGLQNVRVEETRGMLSDHYDPTSRTLRLSSDVYRSNSIAAAGVAAHEAGHALQHKQGYFFLQFRSLMVPTVQLGSWLGPIIFMIGMFIQSTLGTQIATFGLILFAATAVFAFITLPVEFDATKRAKAWLSTSGVLYQSEMTGINSVLDAAALTYVAGAVQAVSTILYYLFLLSGRRSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XSC7</accession>
    <name>A0A0P6XSC7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_12885</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL75531">
        <property type="protein sequence ID" value="KPL75531"/>
        <property type="gene ID" value="ADN00_12885"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL75531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="99" mass="12081" checksum="737F1A30FE73836A" modified="2016-01-20" version="1">MPVFRMVCTRSSNRWWCWRISARCSSRRLRKLCTPCKRRRRWNWSQSRQPMSRSTTCCQRRFVAQTASRWCLSAQIGSRKRWWKQPQRPAFSRQANGLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XT12</accession>
    <name>A0A0P6XT12_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Polyribonucleotide nucleotidyltransferase</fullName>
            <ecNumber evidence="6">2.7.7.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Polynucleotide phosphorylase</fullName>
            <shortName evidence="6">PNPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">pnp</name>
        <name evidence="9" type="ORF">ADN00_12410</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in mRNA degradation. Catalyzes the phosphorolysis of single-stranded polyribonucleotides processively in the 3'- to 5'-direction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>phosphate + RNA(n+1) = a ribonucleoside 5'-diphosphate + RNA(n)</text>
            <dbReference type="Rhea" id="RHEA:22096"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the polyribonucleotide nucleotidyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.8" evidence="6"/>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063332.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12410"/>
    <dbReference type="EnsemblBacteria" id="KPL76134">
        <property type="protein sequence ID" value="KPL76134"/>
        <property type="gene ID" value="ADN00_12410"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3963"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004654">
        <property type="term" value="F:polyribonucleotide nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01595">
        <property type="entry name" value="PNPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015847">
        <property type="entry name" value="ExoRNase_PH_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012162">
        <property type="entry name" value="PNPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015848">
        <property type="entry name" value="PNPase_PH_RNA-bd_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036456">
        <property type="entry name" value="PNPase_PH_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11252">
        <property type="entry name" value="PTHR11252"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03726">
        <property type="entry name" value="PNPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03725">
        <property type="entry name" value="RNase_PH_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005499">
        <property type="entry name" value="PNPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46915">
        <property type="entry name" value="SSF46915"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="SSF54791"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="SSF55666"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03591">
        <property type="entry name" value="polynuc_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="S1 motif" evidence="8">
        <location>
            <begin position="626"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="705"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="730"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="490"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="496"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007404"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL76134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="752" mass="81857" checksum="481E24DD6E682F4C" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XT21</accession>
    <name>A0A0P6XT21_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">50S ribosomal protein L18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rplR</name>
        <name evidence="9" type="ORF">ADN00_12525</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">This is one of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S and 23S rRNAs.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the universal ribosomal protein uL18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063354.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12525"/>
    <dbReference type="EnsemblBacteria" id="KPL76152">
        <property type="protein sequence ID" value="KPL76152"/>
        <property type="gene ID" value="ADN00_12525"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3986"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01337_B">
        <property type="entry name" value="Ribosomal_L18_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005484">
        <property type="entry name" value="Ribosomal_L18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004389">
        <property type="entry name" value="Ribosomal_L18_bac-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12899">
        <property type="entry name" value="PTHR12899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00861">
        <property type="entry name" value="Ribosomal_L18p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00060">
        <property type="entry name" value="L18_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 7" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL76152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="121" mass="13390" checksum="392E48840C652781" modified="2016-01-20" version="1">MTKMTRSEARERRHNRVRKHISGTPARPRLSVFRSLANINAQVIDDVAGVTLASASSVDRELREKLDGMKKSEQAKLVGQLVAERALAKGVKQVVFDRGGYKYIGRVKALAEAAREAGLEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XTL4</accession>
    <name>A0A0P6XTL4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_02100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000008">
        <property type="protein sequence ID" value="KPL79933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79933">
        <property type="protein sequence ID" value="KPL79933"/>
        <property type="gene ID" value="ADN00_02100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="108" mass="11856" checksum="A2F42AE3C1672FB4" modified="2016-01-20" version="1">MINWAFLTFSADGDGSVSTQLLRIKFLLERADNKRILLINYEFVGFRVAKMTPPPTPPLGGGEKLGLSVEQFIPNSFFPYPCCAGFGYSLNPKSPSLALEYPLKSGHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XTP0</accession>
    <name>A0A0P6XTP0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_11475</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063170.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11475"/>
    <dbReference type="EnsemblBacteria" id="KPL76591">
        <property type="protein sequence ID" value="KPL76591"/>
        <property type="gene ID" value="ADN00_11475"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.996"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005384">
        <property type="term" value="F:manganese ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030026">
        <property type="term" value="P:cellular manganese ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01044">
        <property type="entry name" value="Ferritin_CCC1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008217">
        <property type="entry name" value="Ccc1_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039376">
        <property type="entry name" value="Ferritin_CCC1_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31851">
        <property type="entry name" value="PTHR31851"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01988">
        <property type="entry name" value="VIT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="65"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="128"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="159"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="197"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="222"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="254"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL76591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="283" mass="32082" checksum="23E1E0B3E90BB0F4" modified="2016-01-20" version="1">MEKLLFLQQDEINSHHTYARLAKQVKDENNSAVLKKISEEEKKHYEIWNRYTRMEIRPNWFQVNLFYWLARILGLTFGIKLMELGEEKAQKAYSQLLDRVPEAKQVMEEEEVHEEELMDMLDEEGLKYAGSVVLGLNDALVELTGALAGFSFAFQKTNLIALAGLITGISASFSMAASEYLSQKSEEGEQDPLKSAIYTGVAYIFTVLILVLPYFLFQNYLVSLAFTVFNALVIIAVFNFYISVAKGYSFKRRFTEMALISVGVAAFSFIVGVVVRNVTGIEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XU66</accession>
    <name>A0A0P6XU66_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phage_base_V domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062839.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09900"/>
    <dbReference type="EnsemblBacteria" id="KPL76902">
        <property type="protein sequence ID" value="KPL76902"/>
        <property type="gene ID" value="ADN00_09900"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2440"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006531">
        <property type="entry name" value="Gp5/Vgr_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037026">
        <property type="entry name" value="Vgr_OB-fold_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04717">
        <property type="entry name" value="Phage_base_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phage_base_V" evidence="1">
        <location>
            <begin position="397"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="644" mass="69926" checksum="284EEA29DB70EF84" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUG8</accession>
    <name>A0A0P6XUG8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HTH luxR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_06080</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78793">
        <property type="protein sequence ID" value="KPL78793"/>
        <property type="gene ID" value="ADN00_06080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041617">
        <property type="entry name" value="TPR_MalT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17874">
        <property type="entry name" value="TPR_MalT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="541"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="872"/>
            <end position="937"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL78793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="939" mass="106764" checksum="42F686B5961AC211" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUH7</accession>
    <name>A0A0P6XUH7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_06150</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062087.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06150"/>
    <dbReference type="REBASE" id="132868">
        <property type="entry name" value="OapP3M1McrBCP"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78803">
        <property type="protein sequence ID" value="KPL78803"/>
        <property type="gene ID" value="ADN00_06150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019292">
        <property type="entry name" value="McrC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014407">
        <property type="entry name" value="McrC_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38733">
        <property type="entry name" value="PTHR38733"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10117">
        <property type="entry name" value="McrBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003109">
        <property type="entry name" value="McrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="373" mass="43681" checksum="60A33B8C739F1DE7" modified="2016-01-20" version="1">MYGPAMVDNPTNIYKTEFGIPIRNVWYMLMYAWGEALLNRFGELDDVENAPSLDALLASILVKLIQQRMRIGLGRSYFDEKLLAEGIRGRINFIDSLKHQTFERGQVYCDTHQFSLNVPKNQILRSTLDKLVQIGDFGPDIKMANELRHQIRWLTRQMDGIDLIELKQDFIHRQNLGRNDRDYQVMLFVCELILQRHMPSETGGDIRLPSINKDAQVMHRVYERFIACFYQYHLDGWKVTPQSRLKWFESNTSKYLPVMQPDLLLQEKKSRRIIILDTKFTAKSLIENQWGKVGFDSSHLYQLFTYLKTQEHLSEQNQNATGILLYPTINQTNISEEIGLQNLTIRIETVDLAAPWEEIEYQLLKILKYNVAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XV90</accession>
    <name>A0A0P6XV90_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NTP_transf_9 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061160.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01320"/>
    <dbReference type="EnsemblBacteria" id="KPL80518">
        <property type="protein sequence ID" value="KPL80518"/>
        <property type="gene ID" value="ADN00_01320"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1015"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.150.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007361">
        <property type="entry name" value="DUF427"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038694">
        <property type="entry name" value="DUF427_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04248">
        <property type="entry name" value="NTP_transf_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NTP_transf_9" evidence="1">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="95" mass="10849" checksum="08DB5E3B6D603613" modified="2016-01-20" version="1">MKAVFNGTIIAESEQTQVVEGNHYFPPASLKMEYFLPSDRHTTCPWKGEASYYHIRVGNVEKQNAAWSYPQPKEAARQISGYVAFYPHLVQVVED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XVA9</accession>
    <name>A0A0P6XVA9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">AIR synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_01550</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HypE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061202.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01550"/>
    <dbReference type="EnsemblBacteria" id="KPL80555">
        <property type="protein sequence ID" value="KPL80555"/>
        <property type="gene ID" value="ADN00_01550"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1067"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.650.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011854">
        <property type="entry name" value="HypE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010918">
        <property type="entry name" value="PurM-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036676">
        <property type="entry name" value="PurM-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016188">
        <property type="entry name" value="PurM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036921">
        <property type="entry name" value="PurM-like_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30303">
        <property type="entry name" value="PTHR30303"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00586">
        <property type="entry name" value="AIRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02769">
        <property type="entry name" value="AIRS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005644">
        <property type="entry name" value="Hdrgns_mtr_HypE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55326">
        <property type="entry name" value="SSF55326"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56042">
        <property type="entry name" value="SSF56042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AIRS" evidence="2">
        <location>
            <begin position="39"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="AIRS_C" evidence="3">
        <location>
            <begin position="156"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL80555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="340" mass="36122" checksum="32D29AC6A0FBC979" modified="2016-01-20" version="1">MSLPILPVGKLPISLLQQVIKEAPQLDERILLGPGIGMDCAVIDLGSRCLVIKSDPITFASDQIGWYAVQINANDIATTGAEPKWFSCTLLLPEGKTTPADVLEISRQINQACRDLGISVVGGHTEITYNLDRPLVLGTLIGEVEKERLVTPRGAQPGDVVLLTKGVPVEAVSILAREFAAPLRAILSEEEIQTAAGYLTNPGIGITRDARIAMQAGRVHAMHDPTEGGLAAALWELADASATSLVIEREAVHILPLGARICQFFKLDPLATIASGALLLTAPEADASAIISALQAEGIQCAAIGRVHPGPSAVHEIVEGRTTLLKRPERDDIGRVYTQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XVB5</accession>
    <name>A0A0P6XVB5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_01595</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061210.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80564">
        <property type="protein sequence ID" value="KPL80564"/>
        <property type="gene ID" value="ADN00_01595"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL80564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="337" mass="37610" checksum="56B5338B86677D2A" modified="2016-01-20" version="1">MRITRDTLMKLARNAVAERVYRSRDIICVYLTGSMLKEEPLLGGAADIDMVLVHSSTPEAPREVIQATNEVHIDLCHLSQAYFNQPRKLRKDAWVGGFMCASPLVLHDQQHWFEFTQASVCSQYNAPENVMSRAWPMAEAARTIWFDLHAGRFENPAFTFWQYLRALEKAANAVSILAGLPLTERRFMLEFPARAQALQRPGLASGLTDLFMPAPLPADRRETLLSACQSALEQLGRQPDCPAVLLPQRRVYYLNAVDALWNEQPAAAAWILLRVWTRAVCSLAEPAAAQQTWQTSLADLGLNPADMDASLAALDAYLDGVEETLDTWAAKNGIERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XVC5</accession>
    <name>A0A0P6XVC5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Ribonuclease HII</fullName>
            <shortName evidence="11">RNase HII</shortName>
            <ecNumber evidence="11">3.1.26.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">rnhB</name>
        <name evidence="14" type="ORF">ADN00_01645</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 11 12">Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11 12">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="11">Manganese or magnesium. Binds 1 divalent metal ion per monomer in the absence of substrate. May bind a second metal ion after substrate binding.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 11 12">Belongs to the RNase HII family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.4" evidence="11"/>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061219.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01645"/>
    <dbReference type="EnsemblBacteria" id="KPL80573">
        <property type="protein sequence ID" value="KPL80573"/>
        <property type="gene ID" value="ADN00_01645"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1089"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030145">
        <property type="term" value="F:manganese ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07182">
        <property type="entry name" value="RNase_HII_bacteria_HII_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00052_B">
        <property type="entry name" value="RNase_HII_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022898">
        <property type="entry name" value="RNase_HII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001352">
        <property type="entry name" value="RNase_HII/HIII"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024567">
        <property type="entry name" value="RNase_HII/HIII_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10954">
        <property type="entry name" value="PTHR10954"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10954:SF18">
        <property type="entry name" value="PTHR10954:SF18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01351">
        <property type="entry name" value="RNase_HII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 11 12" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="9 11 12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 11" id="KW-0464">Manganese</keyword>
    <keyword evidence="7 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 11 12" id="KW-0540">Nuclease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase_HII" evidence="13">
        <location>
            <begin position="29"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF01351"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KPL80573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="222" mass="24041" checksum="9A2433E34ED03BA6" modified="2016-01-20" version="1">MKAEIPPQTRYPDLEQEKQLWQRGVVRAAGLDEAGRGAWAGPVCAAAVILPAEESVLETLSGVRDSKLMTARQRAEWAPRVQNAAAAWGVGWASNDEIDAQGILPATRLAMRRAIEALGLPPEHLLIDAVRLRDLPLPQTVLIKGDWRCLSIAAAAVLAKTARDALMAGLDSQYPGYGFAQHKGYGTRRHQSALDALGACALHRRSYAPLRARLLPADESLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XVK3</accession>
    <name>A0A0P6XVK3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Carbonic anhydrase</fullName>
            <ecNumber evidence="3 6">4.2.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Carbonate dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_03060</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Reversible hydration of carbon dioxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>H(+) + hydrogencarbonate = CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:10748"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="EC" id="4.2.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the beta-class carbonic anhydrase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.1" evidence="3 6"/>
    <dbReference type="EMBL" id="LGCL01000014">
        <property type="protein sequence ID" value="KPL79324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061490.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000014.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03060"/>
    <dbReference type="EnsemblBacteria" id="KPL79324">
        <property type="protein sequence ID" value="KPL79324"/>
        <property type="gene ID" value="ADN00_03060"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2023"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004089">
        <property type="term" value="F:carbonate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015976">
        <property type="term" value="P:carbon utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001765">
        <property type="entry name" value="Carbonic_anhydrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015892">
        <property type="entry name" value="Carbonic_anhydrase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036874">
        <property type="entry name" value="Carbonic_anhydrase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11002">
        <property type="entry name" value="PTHR11002"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00484">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00947">
        <property type="entry name" value="Pro_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53056">
        <property type="entry name" value="SSF53056"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00704">
        <property type="entry name" value="PROK_CO2_ANHYDRASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00705">
        <property type="entry name" value="PROK_CO2_ANHYDRASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL79324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="196" mass="20464" checksum="D481BF564AF1F3D7" modified="2016-01-20" version="1">MSAKPQITSQAALQQLQEGNRRFAAGTPLHPHQDETTRQRLISGQSPFAVVVGCSDSRIPPEILFDQGLGDLFVVRAAGNPACDMAQWSAEYAVDHLGAPLLVVLGHSGCGALTAAVQNAAAGQPASGLLALFDSAVREAQTRSGDLLENAIECEACQAAQQLAESGTILPAAIQAGKLLVKAAIYHQDSGLVEWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XWA0</accession>
    <name>A0A0P6XWA0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01225</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000003">
        <property type="protein sequence ID" value="KPL80838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061141.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000003.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80838">
        <property type="protein sequence ID" value="KPL80838"/>
        <property type="gene ID" value="ADN00_01225"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011737">
        <property type="entry name" value="CHP02206_TP0381"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09529">
        <property type="entry name" value="Intg_mem_TP0381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02206">
        <property type="entry name" value="intg_mem_TP0381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="213"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="247" mass="28270" checksum="75A5EDDD66761C1D" modified="2016-01-20" version="1">MISDFFARDYAGGAFVLFGRQHLAALGLVGLVCLLIILFRGYWNGRAKAATRWGLLALIYLCEGSWQVWMWAIGEWSIQGMLPLWLCSVTSWSMPLLLVWRSDRYYQWAYSMGVLGAVMALLTPDLMQYGFPHFRFIEFFTLHGLLIVAVVYMTAVEGFRPRLRSLPWVILVTNLYWVFCAWVNAQIGSNYLYTQGKLPTPSLLDYLGPHPWYLLWMEGIGIGLCLLLYLPWAIRGARQKKVPGAVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XWF9</accession>
    <name>A0A0P6XWF9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Fructokinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_02170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000009">
        <property type="protein sequence ID" value="KPL79790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061322.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000009.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02170"/>
    <dbReference type="EnsemblBacteria" id="KPL79790">
        <property type="protein sequence ID" value="KPL79790"/>
        <property type="gene ID" value="ADN00_02170"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2756"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01125">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="299" mass="31939" checksum="30DA0BB504485CE2" modified="2016-01-20" version="1">MDLFGGIEAGGTKFVCVAGSGPDDIRMEERFPTTSPVETIGKMVAFFQHAEKKLGKKFVSFGVASFGPVDLDTSSPTFGFITSTPKPGWKNTDLIGPLRKTFGVPVGFDTDVNGAAIGEGMWGAGKGLKHFIYITIGTGIGGGAVVDGKPLHGLIHPEMGHMLLPHDWDRDPFEGHCPYHGDCFEGMASGPALKARWGVSADGLPANHSAWDLEADYIASALQNLIAVLSPQRLILGGGVMQQEQLFPLIRGKLLEKMNNYFQSPAILNRMAEYVVPPGLGNQAGMLGALAMARNEIEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XWU3</accession>
    <name>A0A0P6XWU3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_08490</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062556.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77899">
        <property type="protein sequence ID" value="KPL77899"/>
        <property type="gene ID" value="ADN00_08490"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL77899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="108" mass="11895" checksum="E4EACB8A47AB4111" modified="2016-01-20" version="1">MDMTNALEELEKARAARLAGFEGRARVCARRAAVWAIQTKYAASKPLYGLDLLHQVAQDSRMPEHIRARASHLVMSVNTAHELPPGVDLITDAQTIIQFLSQAEEPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XYJ9</accession>
    <name>A0A0P6XYJ9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SBP_bac_5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_07705</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062399.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78328">
        <property type="protein sequence ID" value="KPL78328"/>
        <property type="gene ID" value="ADN00_07705"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002741">
        <property type="entry name" value="MppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133278" description="SBP_bac_5 domain-containing protein" evidence="1">
        <location>
            <begin position="35"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="domain" description="SBP_bac_5" evidence="2">
        <location>
            <begin position="110"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="548" mass="59184" checksum="DC1A649F6A90B97C" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XZ16</accession>
    <name>A0A0P6XZ16_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Endopeptidase La</fullName>
            <ecNumber evidence="1">3.4.21.53</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_06650</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of proteins in presence of ATP.</text>
            <dbReference type="EC" id="3.4.21.53"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.53" evidence="1"/>
    <dbReference type="EMBL" id="LGCL01000018">
        <property type="protein sequence ID" value="KPL78401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062198.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000018.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06650"/>
    <dbReference type="EnsemblBacteria" id="KPL78401">
        <property type="protein sequence ID" value="KPL78401"/>
        <property type="gene ID" value="ADN00_06650"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2238"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041699">
        <property type="entry name" value="AAA_32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008269">
        <property type="entry name" value="Lon_proteolytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027065">
        <property type="entry name" value="Lon_Prtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10046">
        <property type="entry name" value="PTHR10046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13654">
        <property type="entry name" value="AAA_32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05362">
        <property type="entry name" value="Lon_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51786">
        <property type="entry name" value="LON_PROTEOLYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="Lon proteolytic" evidence="3">
        <location>
            <begin position="559"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="211"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="649"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="692"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL78401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="795" mass="88918" checksum="115C8490B4BE4EC9" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XZ61</accession>
    <name>A0A0P6XZ61_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Putative [LysW]-aminoadipate kinase</fullName>
            <ecNumber evidence="6">2.7.2.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">lysZ</name>
        <name evidence="8" type="ORF">ADN00_06685</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the phosphorylation of LysW-gamma-alpha-aminoadipate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>[amino-group carrier protein]-C-terminal-N-(1,4-dicarboxybutan-1-yl)-L-glutamine + ATP = [amino-group carrier protein]-C-terminal-N-(1-carboxy-5-phosphooxy-5-oxopentan-1-yl)-L-glutamine + ADP</text>
            <dbReference type="Rhea" id="RHEA:41944"/>
            <dbReference type="Rhea" id="RHEA-COMP:9694"/>
            <dbReference type="Rhea" id="RHEA-COMP:9712"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:78499"/>
            <dbReference type="ChEBI" id="CHEBI:78503"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Amino-acid biosynthesis; L-lysine biosynthesis via AAA pathway; L-lysine from L-alpha-aminoadipate (Thermus route): step 2/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the acetylglutamate kinase family. LysZ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.17" evidence="6"/>
    <dbReference type="EMBL" id="LGCL01000018">
        <property type="protein sequence ID" value="KPL78438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062240.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000018.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06685"/>
    <dbReference type="EnsemblBacteria" id="KPL78438">
        <property type="protein sequence ID" value="KPL78438"/>
        <property type="gene ID" value="ADN00_06685"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00033">
        <property type="reaction ID" value="UER00036"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043744">
        <property type="term" value="F:N2-acetyl-L-aminoadipate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019878">
        <property type="term" value="P:lysine biosynthetic process via aminoadipic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02082">
        <property type="entry name" value="LysZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004662">
        <property type="entry name" value="AcgluKinase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001057">
        <property type="entry name" value="Glu/AcGlu_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037529">
        <property type="entry name" value="LysZ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000728">
        <property type="entry name" value="NAGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00474">
        <property type="entry name" value="GLU5KINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00761">
        <property type="entry name" value="argB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AA_kinase" evidence="7">
        <location>
            <begin position="2"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="6">
        <location>
            <position position="5"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="6">
        <location>
            <position position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL78438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="269" mass="28026" checksum="BE13CB64A82286D6" modified="2016-01-20" version="1">MTVVKLGGTEGVDFGAICADAQQLVQSGQRLVLVHGGSAEANALGEQLGTPPKFVVSPSGFSSRYTDRATLEVFAMAVNGKVNTFLVEQLQMLGVNALGLSGLDGRLLQATRKDTIRSVENGKVKLIRDDYTGKIEQVNAGLLEMLLQGSFVPVIAPLAASQKGEALNVDADRAAAMVAAALGAENLLLLTAVPGLMRSFPDESTLIHSLTLARLDDALQVAEGRMKKKVLGAQEALEGGVGRVIIADGRVAQPISAALKGQGTVITAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y2I5</accession>
    <name>A0A0P6Y2I5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_04610</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061783.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79142">
        <property type="protein sequence ID" value="KPL79142"/>
        <property type="gene ID" value="ADN00_04610"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="264" mass="30148" checksum="E86B0A5FBC4A88BC" modified="2016-01-20" version="1">MEPEEITSIGIEISGGRHPFTFLAVDDTCRLLAQGSGHLEDVLAFCAGQTAARVAVNAPPRPNQQVMAHQETRQSLFPDLSPGRWTQLRLAEYELHQAGISIPRTPSQPEDCPAWMRLGFKLYHHLQELGYQPYPGEAERQWLETQSNAAYWSLMNHAQPFHEKTLEGRLQRQLVLHQISLPVSDPMRFFEELTRHRLLNGILPLESIFSPEELNAWAAVYTAWCSIHHPENLVRFGDPQEGVIYLPFRPQESNTRRAFSDVGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y3H4</accession>
    <name>A0A0P6Y3H4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MAF_flag10 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_11965</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11965"/>
    <dbReference type="EnsemblBacteria" id="KPL76172">
        <property type="protein sequence ID" value="KPL76172"/>
        <property type="gene ID" value="ADN00_11965"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3869"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002826">
        <property type="entry name" value="MptE-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01973">
        <property type="entry name" value="MAF_flag10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MAF_flag10" evidence="1">
        <location>
            <begin position="8"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="225" mass="25864" checksum="7CE6D619B5A7C31E" modified="2016-01-20" version="1">MANLARYKDIHRGERCFIIGNGPSLKNTDLSKLKGEYTFGMNRIYMLFEELGFETSYYVSINDLVIEQCAQDIQRLKLPRFISWRGRQWLQPDNDLFFLYTTYTGPKFSGDIRGRIWEGATVTNVALQIAYFMGFETVVLIGVDHSFATQGKPNTTVVSEGDDPNHFHPGYFGKGFRWQLPDLDTSERGYWMARQAYEKAGRKVLDATVGGKLQIFDKVEYSSLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y638</accession>
    <name>A0A0P6Y638_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aamy domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_01020</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000003">
        <property type="protein sequence ID" value="KPL80852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01020"/>
    <dbReference type="EnsemblBacteria" id="KPL80852">
        <property type="protein sequence ID" value="KPL80852"/>
        <property type="gene ID" value="ADN00_01020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022567">
        <property type="entry name" value="DUF3459"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045857">
        <property type="entry name" value="O16G_dom_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11941">
        <property type="entry name" value="DUF3459"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aamy" evidence="3">
        <location>
            <begin position="15"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL80852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="537" mass="62457" checksum="BBF01C6F25EE88B9" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y6S2</accession>
    <name>A0A0P6Y6S2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_09135</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062688.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77287">
        <property type="protein sequence ID" value="KPL77287"/>
        <property type="gene ID" value="ADN00_09135"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4061"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL77287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="464" mass="50823" checksum="404BD7A5F6D89C09" modified="2016-01-20" version="1">MVSSFDLIAPKMIPPLDEHFRPAVLANRAFEAQAAQYAVPLVIGLERSGGEISRFETNIFPEDHPQAVANYAYVERLVKFLLWQRGGFRVYIGGPASIGAYLREVYSPTGERKFDVHFMGSQVYEQAFEIVSCRPEDVPPARESSKPLGRHLDGCRIGFDLGASDRKVSAVVDGKVVYSEEVVWEPREHANPHYHYQEILSALKTAAGHMPRVDAIGGSSAGIYIDNCPKVASLFRNIPGEHFGEVKSLFQRIQSEMGVPLEIINDGDVTALAGSMSLEDNGILGIALGSSEAAGYVDMNGHITGWLNELSFAPIDYNPNAAVEEWSGDIGCGSSYFSQQCVFRLAPRAGIEIPAGLTMADQLKFVQEKLESGHAGAEQIWQTMGIYLGYGLAHYADFYDIKHVLILGRCTSGRGGDLLLEGAKKVLEVEFPGLYERLQIQLPDEKSRRVGQSIAAASLPALKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y8Z0</accession>
    <name>A0A0P6Y8Z0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transport permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_06905</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ABC-2 integral membrane protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062251.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78211">
        <property type="protein sequence ID" value="KPL78211"/>
        <property type="gene ID" value="ADN00_06905"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00164">
        <property type="entry name" value="ABC2TRNSPORT"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="117"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="150"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="182"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="240"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="7">
        <location>
            <begin position="22"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL78211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="275" mass="30768" checksum="6DAE2980D52ED7C9" modified="2016-01-20" version="1">MTTLVLQLRASYAFVERNLNLVRRYWSWEMVWMVYSIADSLAVSFIGLGMEQIGGGSNVDTDFLVLYLLIGTLVWRFLSTIFYWITDVISVERWEGTIEYTLMAPVRRITHISGQTLFSMAYAMFFTGVILTVVSMILDVDLSQANLFSGAVMLMAGSFSFVGISVIASVLPLLFPERGAQMTHVIIALLLLISGVYYPINVLPGFLQKLAVFSPATYVLDGVRKALLEGTDVAGLWPNIWPVLLFGAGLIPLGLWIFRQAEYYAKRKGKLHRNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y940</accession>
    <name>A0A0P6Y940_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">zinc_ribbon_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_07295</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78265">
        <property type="protein sequence ID" value="KPL78265"/>
        <property type="gene ID" value="ADN00_07295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026870">
        <property type="entry name" value="Zinc_ribbon_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13240">
        <property type="entry name" value="zinc_ribbon_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="zinc_ribbon_2" evidence="2">
        <location>
            <begin position="14"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="75" mass="8540" checksum="FE4A86A572299AFD" modified="2016-01-20" version="1">MAGMDEQQPDNQPCKYCGRPIPSGAPFCYYCGRELIARPERPMQTEKNHWPLWLTLIGVFGGAAVILFVMFQLLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YA32</accession>
    <name>A0A0P6YA32_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chemotaxis protein CheW</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05335</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061939.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05335"/>
    <dbReference type="EnsemblBacteria" id="KPL78677">
        <property type="protein sequence ID" value="KPL78677"/>
        <property type="gene ID" value="ADN00_05335"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1539"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039315">
        <property type="entry name" value="CheW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036061">
        <property type="entry name" value="CheW-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002545">
        <property type="entry name" value="CheW-lke_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22617">
        <property type="entry name" value="PTHR22617"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01584">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00260">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50341">
        <property type="entry name" value="SSF50341"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50851">
        <property type="entry name" value="CHEW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CheW-like" evidence="1">
        <location>
            <begin position="2"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="149" mass="16117" checksum="0D69534F26340154" modified="2016-01-20" version="1">MEKQLVIFTLAGEQFGIDIASVESIIKLQRITSVPQAPDFVEGITNLRGAVLPVVNLERRFGLPAQPQTSETRIVVANIGGLKIGMIVASVSEVLNVEESLIEPPPPIATSINTEFIIGVAKFDSRLIILLDLSRVLTSDEQKLASQLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YAC6</accession>
    <name>A0A0P6YAC6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Pyruvate formate-lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_06040</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062068.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06040"/>
    <dbReference type="EnsemblBacteria" id="KPL78787">
        <property type="protein sequence ID" value="KPL78787"/>
        <property type="gene ID" value="ADN00_06040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1687"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001150">
        <property type="entry name" value="Gly_radical"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004184">
        <property type="entry name" value="PFL_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01228">
        <property type="entry name" value="Gly_radical"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02901">
        <property type="entry name" value="PFL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51149">
        <property type="entry name" value="GLY_RADICAL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51554">
        <property type="entry name" value="PFL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="1 2" id="KW-0556">Organic radical</keyword>
    <keyword evidence="5" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PFL" evidence="4">
        <location>
            <begin position="3"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="domain" description="Glycine radical" evidence="3">
        <location>
            <begin position="683"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="modified residue" description="Glycine radical" evidence="2">
        <location>
            <position position="779"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL78787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="803" mass="89429" checksum="774534D329488967" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YB07</accession>
    <name>A0A0P6YB07_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glucose-6-phosphate isomerase</fullName>
            <shortName evidence="7">GPI</shortName>
            <ecNumber evidence="7">5.3.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Phosphoglucose isomerase</fullName>
            <shortName evidence="7">PGI</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Phosphohexose isomerase</fullName>
            <shortName evidence="7">PHI</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7 9" type="primary">pgi</name>
        <name evidence="9" type="ORF">ADN00_04395</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the reversible isomerization of glucose-6-phosphate to fructose-6-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7 8">
            <text>alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:11816"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="EC" id="5.3.1.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 7 8">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7 8">Belongs to the GPI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.9" evidence="7"/>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061739.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04395"/>
    <dbReference type="EnsemblBacteria" id="KPL79107">
        <property type="protein sequence ID" value="KPL79107"/>
        <property type="gene ID" value="ADN00_04395"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.235"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00181"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004347">
        <property type="term" value="F:glucose-6-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05015">
        <property type="entry name" value="SIS_PGI_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05016">
        <property type="entry name" value="SIS_PGI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00473">
        <property type="entry name" value="G6P_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001672">
        <property type="entry name" value="G6P_Isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023096">
        <property type="entry name" value="G6P_Isomerase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018189">
        <property type="entry name" value="Phosphoglucose_isomerase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035476">
        <property type="entry name" value="SIS_PGI_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035482">
        <property type="entry name" value="SIS_PGI_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11469">
        <property type="entry name" value="PTHR11469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00342">
        <property type="entry name" value="PGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00662">
        <property type="entry name" value="G6PISOMERASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00765">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00174">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51463">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 7 8" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="4 7 8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="5 7 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="353"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="384"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL79107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="547" mass="60801" checksum="DCFC8A2E120507B0" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YBS3</accession>
    <name>A0A0P6YBS3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LytR_cpsA_psr domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_02955</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LytR/CpsA/Psr (LCP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000013">
        <property type="protein sequence ID" value="KPL79399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061463.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000013.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02955"/>
    <dbReference type="EnsemblBacteria" id="KPL79399">
        <property type="protein sequence ID" value="KPL79399"/>
        <property type="gene ID" value="ADN00_02955"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004474">
        <property type="entry name" value="LytR_CpsA_psr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03816">
        <property type="entry name" value="LytR_cpsA_psr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00350">
        <property type="entry name" value="lytR_cpsA_psr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LytR_cpsA_psr" evidence="3">
        <location>
            <begin position="116"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="37"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL79399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="416" mass="45355" checksum="09E5FAC3DACEA4A3" modified="2016-01-20" version="1">MKTRAFRPFWQWLLVGMTALGIFGLLLAAGCSPAATPAAELSPSASPTLSATPSNTPTITLTPTITPPPAVWGSFPPPSLDPVTPIPPPIQGIQLPQGINAILLLGTDRNSPYVGRTDAVVLVLHDPAHSRASVISLPPDLMVYIPGQTMQRLQVAYALGGFDLMAQTLEYNFGIRPDDWVLLHLDDFSGLVDDLGGLFVNIQKEDEEICGGLKEGFRKLNGSSALCYVSYRTGPDESSRNRRQHEALRRLLIQLVQGGTLNRLPELFEKYAPRVDTSLELPSLLDSIPLLLNLGVEERVQYYSLVDQDLTPWQLPGPAPAVVLLPDREGLIEMISEAAEFVSQEAEPNEYVATLQYELTVSPTPTNTPTFTPSPTRTITPTRTVTRTRTITPTRTATRTRTITPTATSTTPVPYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YC59</accession>
    <name>A0A0P6YC59_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Phosphate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_02520</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PstS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000011">
        <property type="protein sequence ID" value="KPL79573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061384.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000011.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02520"/>
    <dbReference type="EnsemblBacteria" id="KPL79573">
        <property type="protein sequence ID" value="KPL79573"/>
        <property type="gene ID" value="ADN00_02520"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2814"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042301">
        <property type="term" value="F:phosphate ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024370">
        <property type="entry name" value="PBP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011862">
        <property type="entry name" value="Phos-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12849">
        <property type="entry name" value="PBP_like_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02136">
        <property type="entry name" value="ptsS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133496" evidence="4">
        <location>
            <begin position="21"/>
            <end position="645"/>
        </location>
    </feature>
    <feature type="domain" description="PBP_domain" evidence="5">
        <location>
            <begin position="73"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="PBP_domain" evidence="5">
        <location>
            <begin position="368"/>
            <end position="614"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL79573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="645" mass="69467" checksum="BA75627DBF1C0045" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YEN5</accession>
    <name>A0A0P6YEN5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GGDEF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_01575</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061206.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80560">
        <property type="protein sequence ID" value="KPL80560"/>
        <property type="gene ID" value="ADN00_01575"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1073"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="254"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="2">
        <location>
            <begin position="327"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL80560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="447" mass="51367" checksum="0EA72065CCE8D50B" modified="2016-01-20" version="1">MHDLLKKTRLLTLLFFIGVVLLTILVVFLPLEMQLEDTLVSNWVLTAQSRSLSFHLFLEKNTEGAQSVSSRSVIRDQLAEYHQQELSWEDLQASTQPKYVEGVRVLENLAYAYRVVEGKILAAYRAADASPTVDDEFVFLDDIPEFAVLNQAGQHYVVVSSEVKKENQCLGKDVLIYSLDPILEQLNNAEIQVSIISEADLSPFLNLPVLRSGKDYRVVKEEGNLYYLECLPDSQHYLSVQTPLKQIVGPTRQGIGFFLVIYLLGQMLLFLLARRGILQYANLMINQVEKSKEEFRAFAYHDTLTGSYSRLSLEHWLERQAKTGYKKALTVVLLDIDMFKDINDTYGHKTGDEVLITLSKTVHRCIRKDDLLVRYGGDEFLIIFQDIDRTWVKDIMSRIEQQLAQDHSFEFPIEISYGMVEIKDINHFYDGLKQADKQMYAQKNGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YF71</accession>
    <name>A0A0P6YF71_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000003">
        <property type="protein sequence ID" value="KPL80807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80807">
        <property type="protein sequence ID" value="KPL80807"/>
        <property type="gene ID" value="ADN00_01030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133560" evidence="1">
        <location>
            <begin position="23"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="194" mass="20110" checksum="33A14BF297F18974" modified="2016-01-20" version="1">MNRKIAIMFGLVMLAAAMLACASLPFGGVQEAVESAKEAAETAQPLALTAAAGAPELVETMQPLALTAAANAPELLETAQPAAATAAAEAQEELGEVSIGENTSPFPVPEGAENVMSTESPLNFQVKMTLDAAMQYYRDQLGAQGLTERADLASVEGGTFSMVFEGGPEGKSVVVQGVALGELMNINVRYEEMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GL41</accession>
    <name>A0A0N8GL41_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein-glutamate methylesterase/protein-glutamine glutaminase</fullName>
            <ecNumber evidence="3">3.1.1.61</ecNumber>
            <ecNumber evidence="3">3.5.1.44</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cheB</name>
        <name evidence="8" type="ORF">ADN00_17295</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in chemotaxis. Part of a chemotaxis signal transduction system that modulates chemotaxis in response to various stimuli. Catalyzes the demethylation of specific methylglutamate residues introduced into the chemoreceptors (methyl-accepting chemotaxis proteins or MCP) by CheR. Also mediates the irreversible deamidation of specific glutamine residues to glutamic acid.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>H2O + L-glutaminyl-[protein] = L-glutamyl-[protein] + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:16441"/>
            <dbReference type="Rhea" id="RHEA-COMP:10207"/>
            <dbReference type="Rhea" id="RHEA-COMP:10208"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29973"/>
            <dbReference type="ChEBI" id="CHEBI:30011"/>
            <dbReference type="EC" id="3.5.1.44"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>[protein]-L-glutamate 5-O-methyl ester + H2O = H(+) + L-glutamyl-[protein] + methanol</text>
            <dbReference type="Rhea" id="RHEA:23236"/>
            <dbReference type="Rhea" id="RHEA-COMP:10208"/>
            <dbReference type="Rhea" id="RHEA-COMP:10311"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17790"/>
            <dbReference type="ChEBI" id="CHEBI:29973"/>
            <dbReference type="ChEBI" id="CHEBI:82795"/>
            <dbReference type="EC" id="3.1.1.61"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="3">Contains a C-terminal catalytic domain, and an N-terminal region which modulates catalytic activity.</text>
    </comment>
    <comment type="PTM">
        <text evidence="3">Phosphorylated by CheA. Phosphorylation of the N-terminal regulatory domain activates the methylesterase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CheB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.61" evidence="3"/>
    <dbReference type="EC" id="3.5.1.44" evidence="3"/>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71442.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064303.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17295"/>
    <dbReference type="EnsemblBacteria" id="KPL71442">
        <property type="protein sequence ID" value="KPL71442"/>
        <property type="gene ID" value="ADN00_17295"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.522"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000156">
        <property type="term" value="F:phosphorelay response regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008984">
        <property type="term" value="F:protein-glutamate methylesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050568">
        <property type="term" value="F:protein-glutamine glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018277">
        <property type="term" value="P:protein deamination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006482">
        <property type="term" value="P:protein demethylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16432">
        <property type="entry name" value="CheB_Rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00099">
        <property type="entry name" value="CheB_chemtxs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008248">
        <property type="entry name" value="CheB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035909">
        <property type="entry name" value="CheB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000673">
        <property type="entry name" value="Sig_transdc_resp-reg_Me-estase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01339">
        <property type="entry name" value="CheB_methylest"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000876">
        <property type="entry name" value="RR_chemtxs_CheB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52738">
        <property type="entry name" value="SSF52738"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50122">
        <property type="entry name" value="CHEB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="6">
        <location>
            <begin position="18"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="CheB-type methylesterase" evidence="7">
        <location>
            <begin position="173"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="active site" evidence="3 4">
        <location>
            <position position="185"/>
        </location>
    </feature>
    <feature type="active site" evidence="3 4">
        <location>
            <position position="212"/>
        </location>
    </feature>
    <feature type="active site" evidence="3 4">
        <location>
            <position position="305"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="3 5">
        <location>
            <position position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL71442.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="363" mass="38662" checksum="531645E4BE137611" modified="2016-01-20" version="1">MNEKPSASSPESGNPPIRVLVVDDSAFMRFTITRHLSETAGIQVIGSARDGKEALQLIPELKPDVVTLDVEMPHLDGLSTLREIMAEFPVPVIMVSSLTKEGAVETIQALTYGAVDFVAKPSNKASVSAIVEELVTKIQRASRARVTRMQRRAITLPQQTASPAASNKSVRALRRGEPLVLIGSSTGGPRALNTLIPMLAADTPAAFVIVQHMPAGFTRSLAERLDSLSGLSVKEAEPGDIPEVGKVLLAPGGFHMVFDQNMQVTLNQNPTVHGVRPSVDVTMNSLVQHCPAPLLGVILTGMGSDGTTGCTLIHSRGGKILVEDESTCVVWGMPRSVMEAGVADQIVPLDLMAQAITNTIRKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GL44</accession>
    <name>A0A0N8GL44_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NYN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_17450</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71466.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064329.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL71466">
        <property type="protein sequence ID" value="KPL71466"/>
        <property type="gene ID" value="ADN00_17450"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.558"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021139">
        <property type="entry name" value="NYN_MARF1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01936">
        <property type="entry name" value="NYN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NYN" evidence="2">
        <location>
            <begin position="9"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL71466.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="371" mass="40967" checksum="8BE9C2132561CA5D" modified="2016-01-20" version="1">MRTPPTSPRAAVFLDFENLVSTSKNLSRRGVGDYGSSPEVDFAAFVRHVEAQYGSLAKEDFVAAANFSHYNAQLGGLNRWATLLEVDSFEPRSVRQQEQTSAGKRHVIQQYADMALAFAAGIHAARQPADVYIFITGDKSFAAVAAAIRDQFQKQVVFFLPDPNQSASVTLKERFLCFPFSATQPEPAAVEEEPAPEPPPSPALENPSNQVKPLVTHLRSELRTAIPADLVRAVLGPAGAQKLLDRARSEEQIDLWHNEQGIECVSSRAERLFGKLQIMESRPSVVEAARILLAVASAGESRQPPGTRADWRRCLKESANLSNTAAKQWLERLLDHGILRDRAITRPLITRANLTALIQEYEQTSYQNGPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GLB5</accession>
    <name>A0A0N8GLB5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_16240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064091.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72034">
        <property type="protein sequence ID" value="KPL72034"/>
        <property type="gene ID" value="ADN00_16240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="432"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="463"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="502"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="529"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="570"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="600" mass="65550" checksum="A87B202DF4BE8963" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GLD8</accession>
    <name>A0A0N8GLD8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">NADP oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_15455</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I 51 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063933.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15455"/>
    <dbReference type="EnsemblBacteria" id="KPL72218">
        <property type="protein sequence ID" value="KPL72218"/>
        <property type="gene ID" value="ADN00_15455"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.793"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11540">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001949">
        <property type="entry name" value="NADH-UbQ_OxRdtase_51kDa_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011538">
        <property type="entry name" value="Nuo51_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037225">
        <property type="entry name" value="Nuo51_FMN-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019575">
        <property type="entry name" value="Nuop51_4Fe4S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037207">
        <property type="entry name" value="Nuop51_4Fe4S-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01512">
        <property type="entry name" value="Complex1_51K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10589">
        <property type="entry name" value="NADH_4Fe-4S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00928">
        <property type="entry name" value="NADH_4Fe-4S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140490">
        <property type="entry name" value="SSF140490"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142019">
        <property type="entry name" value="SSF142019"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00644">
        <property type="entry name" value="COMPLEX1_51K_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00645">
        <property type="entry name" value="COMPLEX1_51K_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NADH_4Fe-4S" evidence="6">
        <location>
            <begin position="441"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL72218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="540" mass="58504" checksum="10062E04A0F35CEA" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GM29</accession>
    <name>A0A0N8GM29_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 10">Adenylosuccinate synthetase</fullName>
            <shortName evidence="8">AMPSase</shortName>
            <shortName evidence="8">AdSS</shortName>
            <ecNumber evidence="8 10">6.3.4.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">IMP--aspartate ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">purA</name>
        <name evidence="11" type="ORF">ADN00_14200</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 10">
            <text>GTP + IMP + L-aspartate = GDP + 2 H(+) + N(6)-(1,2-dicarboxyethyl)-AMP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:15753"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57567"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="6.3.4.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8 10">Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1 8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8 10">Belongs to the adenylosuccinate synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.4" evidence="8 10"/>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063686.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000033.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14200"/>
    <dbReference type="EnsemblBacteria" id="KPL74146">
        <property type="protein sequence ID" value="KPL74146"/>
        <property type="gene ID" value="ADN00_14200"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1942"/>
    <dbReference type="UniPathway" id="UPA00075">
        <property type="reaction ID" value="UER00335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004019">
        <property type="term" value="F:adenylosuccinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044208">
        <property type="term" value="P:'de novo' AMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03108">
        <property type="entry name" value="AdSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00011">
        <property type="entry name" value="Adenylosucc_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018220">
        <property type="entry name" value="Adenylosuccin_syn_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033128">
        <property type="entry name" value="Adenylosuccin_syn_Lys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042109">
        <property type="entry name" value="Adenylosuccinate_synth_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042110">
        <property type="entry name" value="Adenylosuccinate_synth_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042111">
        <property type="entry name" value="Adenylosuccinate_synth_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001114">
        <property type="entry name" value="Adenylosuccinate_synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11846">
        <property type="entry name" value="PTHR11846"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00709">
        <property type="entry name" value="Adenylsucc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00788">
        <property type="entry name" value="Adenylsucc_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00184">
        <property type="entry name" value="purA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01266">
        <property type="entry name" value="ADENYLOSUCCIN_SYN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00513">
        <property type="entry name" value="ADENYLOSUCCIN_SYN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8 10" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 8 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 8 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 8 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 8 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 8 10" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="IMP binding" evidence="8">
        <location>
            <begin position="13"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="region of interest" description="IMP binding" evidence="8">
        <location>
            <begin position="38"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8">
        <location>
            <begin position="304"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="13"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="41"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="141"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="12"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="40"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="225"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="240"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="308"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="310"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="336"/>
            <end position="338"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="413"/>
            <end position="415"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL74146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="424" mass="46621" checksum="F22A6D3154D7F9AB" modified="2016-01-20" version="1">MTLDILIGMQWGDEGKGRFVDMLSGEADYVARFAGGDNAGHTIRIGERVYKLHLIPSGIIYPQTFGVLGGGMVINPGVLLEEMQMLRGAGVRIEPDRLKISHVAQVITPGHRALDAAREASLGARKIGTTGRGIGPAYEHKARRSNLRFVDLLDARRMEEILRRNLESINAELNGVFQQPALDVEPIVRDYLGYAEQLRPYIADVSEILIDALDAGRYVIAEGAQGALLDIDYGTYPYVTSSSTVAANALVGLGIGLRREARVIGVAKVFQTRVGEGPFPTELRDEIAAYLRGDGSKQWDEFGTTTGRPRRIGWLDGVMLRHVARTNHVDELALTKLDVLSGLEEIKVCVGYAGVQAGQEFLALESAQPVYRSFPGWTGDLQGITRWEDLPSEARVYVEFIEEISGVPARWVSVGPERNQLIRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNJ7</accession>
    <name>A0A0N8GNJ7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">3-phosphoglycerate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_07445</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062353.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07445"/>
    <dbReference type="EnsemblBacteria" id="KPL78290">
        <property type="protein sequence ID" value="KPL78290"/>
        <property type="gene ID" value="ADN00_07445"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3313"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2-Hacid_dh" evidence="2">
        <location>
            <begin position="21"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="2-Hacid_dh_C" evidence="3">
        <location>
            <begin position="124"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL78290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="307" mass="33253" checksum="043F7ECEC82BAD59" modified="2016-01-20" version="1">MTKVLLATEKPFSPAAVKQIQAVVEEAGFEFALLEKYTAPEQFYQAVSGADALIVRSDLVTPQVLEAAKALKIVVRAGAGFDNIDLPTATAKGVVVMNTPGQNANAVAELALGMMVYLARGCFNGKSGSELRGKTLGLHAFGNVGRRVAEIAKGFGMHVYAYDPFLTKDAIENEGVTALASVEQLYDTCQYVSLHIPANEQTRGSINYALLNRMPQGATLVNTARKEVVNEADLLKIFAERPDFKYLSDVTPDCAAEIAEKFPGRFYFTPKKMGAQTEEANVNAGIAAANQIRDFFQKGDTRFQVNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNK5</accession>
    <name>A0A0N8GNK5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cystathionine gamma-synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_07460</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07460"/>
    <dbReference type="EnsemblBacteria" id="KPL78354">
        <property type="protein sequence ID" value="KPL78354"/>
        <property type="gene ID" value="ADN00_07460"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003962">
        <property type="term" value="F:cystathionine gamma-synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00614">
        <property type="entry name" value="CGS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044639">
        <property type="entry name" value="CGS1/2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43379">
        <property type="entry name" value="PTHR43379"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00868">
        <property type="entry name" value="CYS_MET_METAB_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL78354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="396" mass="43040" checksum="4B3A46DF509BED27" modified="2016-01-20" version="1">MHSGHESTAAVHAGARRAKPYHSLIDPIVPTSTYTFDNTADLVSYMEAHLAGKDEGRVEYGRYGNPTVSAVEERLAALEGAEQAVLLGSGMASITTTLLTFLSAGDELIITDDCYRRTRQFCGEFLKKLKIGCTVVPMGNYTALERAINPRTRLLVSETPTNPYLRVLDVERFAEIGRRFGVTTLVDSTFATPLNLQPLNWGIDLVAHSATKYLGGHNDLLAGVVAGSREKITAIRETNGVMGAVSDANTAYLLLRGLKTLGVRVRHQNDTGLQVAQFLASHPAIERVWYPGLSSHPDHETALRQMSDFGGVVSFTVRGDLRRTSQFVDALQIPYISPSLGGTESLVGQPALVSYYPYSPEERHALGIADNLVRLALGLEDADDLIADLKQALAFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNR5</accession>
    <name>A0A0N8GNR5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_06350</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78834">
        <property type="protein sequence ID" value="KPL78834"/>
        <property type="gene ID" value="ADN00_06350"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012318">
        <property type="entry name" value="HTH_CRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13545">
        <property type="entry name" value="HTH_Crp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00419">
        <property type="entry name" value="HTH_CRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51063">
        <property type="entry name" value="HTH_CRP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="2">
        <location>
            <begin position="24"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="HTH crp-type" evidence="3">
        <location>
            <begin position="137"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL78834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="217" mass="24826" checksum="44D5386BA8480F4F" modified="2016-01-20" version="1">MSENSSIYSRLWGDLFAGHPTLSFKKNTVIIEEGETIDRVYYIVSGRVKFSIITSEGNEKTMYVLNKGSVFGDVWSAAHRPYFLSATTLTKCTLAYKTPSEFIATVSSNPQYMQDWLSYICEIVEFLVEHITDITFLDREALLRKYLYRLSFNYGIPTDEGMKLNTRITHQLLADLIGCSRVTISKIMAKLLRTGELTKIDGFFYIPDINTFKDADE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNU0</accession>
    <name>A0A0N8GNU0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Beta-glucosidase</fullName>
            <ecNumber evidence="2 6">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_03850</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the glycosyl hydrolase 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="2 6"/>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061646.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03850"/>
    <dbReference type="EnsemblBacteria" id="KPL79034">
        <property type="protein sequence ID" value="KPL79034"/>
        <property type="gene ID" value="ADN00_03850"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.124"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102483">
        <property type="term" value="F:scopolin beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001360">
        <property type="entry name" value="Glyco_hydro_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017736">
        <property type="entry name" value="Glyco_hydro_1_beta-glucosidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033132">
        <property type="entry name" value="Glyco_hydro_1_N_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10353">
        <property type="entry name" value="PTHR10353"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00232">
        <property type="entry name" value="Glyco_hydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00131">
        <property type="entry name" value="GLHYDRLASE1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03356">
        <property type="entry name" value="BGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00653">
        <property type="entry name" value="GLYCOSYL_HYDROL_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="407"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="167"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="353"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="21"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="295"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="400"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR617736-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR617736-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL79034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="448" mass="50300" checksum="BD4F2E626315D08D" modified="2016-01-20" version="1">MSSEVKFPDGFVWGAATAAYQIEGGWNEDGRGESIWDRFSHTPGKVLNGDTGDVACDHYHRWREDIALMKDLGIKAYRFSTAWPRILPQGRGKVNPAGLDFYSRLVDALLEAEITPFVTLYHWDLPQALEDQGGWPARETAAAFVEYAGATTRALGDRVKHWITLNEPFVSAFVGYRDGRHAPGRTSLEDSFAAAHHLLLAHAHSLPVIRQNAAGAQAGIVLDIIPAYPASVSAEDQQAAWMARAAHHLWFLEPLVGRGYPQAVADYFKMKLEFIQPGDLNAMAAPLDFLGVNYYTRRIARSAEIAEEDNLPVTVTAAQHKTEMGWEIYPQGLLDVLVWLNERYTFPALYITENGGAFPDALDEKGQVLDEDRVAYLREHFRMSAAAIQEGVPLKGYFAWSLMDNFEWGFGCSKRFGLIYVDYESLKRTPKLSYAWYRQVIRQNGFAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNV1</accession>
    <name>A0A0N8GNV1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_04485</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04485"/>
    <dbReference type="EnsemblBacteria" id="KPL79122">
        <property type="protein sequence ID" value="KPL79122"/>
        <property type="gene ID" value="ADN00_04485"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="SSF54285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="91" mass="10133" checksum="B7BC6C328DA5779E" modified="2016-01-20" version="1">MIEFLGVARNVTGIRKFPIKVSEQATYHDVTRLLSEMYPTLVGEVIHESGDTFIESNVISRNGQQMIRSEQFHQQPADGDLLLVMSILAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNV2</accession>
    <name>A0A0N8GNV2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_04525</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061766.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79130">
        <property type="protein sequence ID" value="KPL79130"/>
        <property type="gene ID" value="ADN00_04525"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.530.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036593">
        <property type="entry name" value="CPE0013-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012460">
        <property type="entry name" value="DUF1667"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39450">
        <property type="entry name" value="PTHR39450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07892">
        <property type="entry name" value="DUF1667"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160148">
        <property type="entry name" value="SSF160148"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="125" mass="13576" checksum="FC69CE3D22AEE261" modified="2016-01-20" version="1">MPEETVKKLICIACPKGCSLDVSMSGETIVKVEGASCKQGYEYAEREIHDPRRMVASTVKVKGAVHPLVPVYTQSAIPKRQIHELLAELRKVEVQAPVEMGQVVLENALGTGIPVVASRSLPKVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-08-12" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNW1</accession>
    <name>A0A0N8GNW1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DUF4203 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_04995</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061853.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79202">
        <property type="protein sequence ID" value="KPL79202"/>
        <property type="gene ID" value="ADN00_04995"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025256">
        <property type="entry name" value="DUF4203"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13886">
        <property type="entry name" value="DUF4203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="124"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="153"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="179"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4203" evidence="6">
        <location>
            <begin position="8"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL79202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="202" mass="21606" checksum="23CA3620C147A846" modified="2016-01-20" version="1">MIGWISSLLILLAGVAICVAGINLIHEQPALGGLLLGGALGYYLFSFFFIPPAGVGAWFPLIGFAIGGVIGALIARPLYMVILVLTSSMLGGLVGLVISYVLQLGGSPERWKQLSLTINLNDTLQVWLMIIFALALGFLALPFEEFMTMVSTGFVGAAMFVSSLVVLFSGSVALLRNPVFIFFFWFAVGMGGLAWQNHSQQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNX6</accession>
    <name>A0A0N8GNX6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">Elongation factor Ts</fullName>
            <shortName evidence="5">EF-Ts</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">tsf</name>
        <name evidence="7" type="ORF">ADN00_03050</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the EF-Ts family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000014">
        <property type="protein sequence ID" value="KPL79322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061488.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000014.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03050"/>
    <dbReference type="EnsemblBacteria" id="KPL79322">
        <property type="protein sequence ID" value="KPL79322"/>
        <property type="gene ID" value="ADN00_03050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2021"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00050">
        <property type="entry name" value="EF_Ts"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036402">
        <property type="entry name" value="EF-Ts_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001816">
        <property type="entry name" value="Transl_elong_EFTs/EF1B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014039">
        <property type="entry name" value="Transl_elong_EFTs/EF1B_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11741">
        <property type="entry name" value="PTHR11741"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00889">
        <property type="entry name" value="EF_TS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="SSF46934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54713">
        <property type="entry name" value="SSF54713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00116">
        <property type="entry name" value="tsf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 7" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="4 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF_TS" evidence="6">
        <location>
            <begin position="35"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Involved in Mg(2+) ion dislocation from EF-Tu" evidence="5">
        <location>
            <begin position="81"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL79322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="203" mass="22486" checksum="39296D04FD047234" modified="2016-01-20" version="1">MAITTEDIKKLREMTGAGILDCRKALENAEGDFDKALDFLREKGLATAAKRATRNASEGVVELYNHGDGRVGVMVELNCETDFVGRSAAFRTLAHEIALQIAAASPLYINETDIPESVIEHEKAIAVARAKEEGKPEQIIPRIVEGTIKKFMDETVLLRQPYIRDDSITVQELINQNIVSIGESVVVRRFVRWALGETTSSEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WJZ4</accession>
    <name>A0A0P6WJZ4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_18070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL69979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL69979">
        <property type="protein sequence ID" value="KPL69979"/>
        <property type="gene ID" value="ADN00_18070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL69979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="153" mass="17445" checksum="FF3A63C1C33B378E" modified="2016-01-20" version="1">MEHQQIYLIRSAYDLADALWMAPEINLLFMQRKKETVERWKESIHALLDKMDQVFIETCSIPVFQVGLHANLDDLPQKATNGAVEHDLPLPILEATKKLGWALRDYINAMRPADATNIAKPEEGVSQAMITELCQRMVELIFTEVSIQPKDLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WKA3</accession>
    <name>A0A0P6WKA3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">3-isopropylmalate dehydrogenase</fullName>
            <ecNumber evidence="13">1.1.1.85</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">3-IPM-DH</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Beta-IPM dehydrogenase</fullName>
            <shortName evidence="13">IMDH</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">leuB</name>
        <name evidence="16" type="ORF">ADN00_19055</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 14">Catalyzes the oxidation of 3-carboxy-2-hydroxy-4-methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2-oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13 14">
            <text>(2R,3S)-3-isopropylmalate + NAD(+) = 4-methyl-2-oxopentanoate + CO2 + NADH</text>
            <dbReference type="Rhea" id="RHEA:32271"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17865"/>
            <dbReference type="ChEBI" id="CHEBI:35121"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.85"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13 14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="13 14">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="13 14">Binds 1 Mg(2+) or Mn(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 13 14">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 13 14">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.85" evidence="13"/>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064627.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_19055"/>
    <dbReference type="EnsemblBacteria" id="KPL70134">
        <property type="protein sequence ID" value="KPL70134"/>
        <property type="gene ID" value="ADN00_19055"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3124"/>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00072"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003862">
        <property type="term" value="F:3-isopropylmalate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01033">
        <property type="entry name" value="LeuB_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004429">
        <property type="entry name" value="Isopropylmalate_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42979">
        <property type="entry name" value="PTHR42979"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00169">
        <property type="entry name" value="leuB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00470">
        <property type="entry name" value="IDH_IMDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="12 13 14" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 13 14" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="9 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="13" id="KW-0464">Manganese</keyword>
    <keyword evidence="8 13 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11 13 14" id="KW-0520">NAD</keyword>
    <keyword evidence="10 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Iso_dh" evidence="15">
        <location>
            <begin position="4"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="76"/>
            <end position="89"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="223"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="247"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="281"/>
            <end position="293"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="13">
        <location>
            <position position="141"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalysis" evidence="13">
        <location>
            <position position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008319"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU004445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KPL70134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="352" mass="37398" checksum="78D7C6CAF71B9EC7" modified="2016-01-20" version="1">MQAYIALTPGDGIGPEVVAQAQRMLDAVAARYGHTFRYTTHLIGGCSIDQHGTALTDEALAACQSADAVLLGAVGGPKWDDPNAAVRPEQGLLKLRKGLGVFANLRPVKVHHALLDASPIKPEVLKNVDMVVVRELTGGLYFGSPKGEDVVNGQAHAVDTMEYTESEVERVVRLAFQMAQNRKKKVTSVDKANVLATSRLWRRVTNRVAADYPDVTLEHMLVDTASMKLIASPASFDVMVTENTFGDILTDEASLLAGSMGLLPSASLGESGPGLYEPIHGSAPDIAGKGTANPIGTILSAALLLRYSLKLEVEAAALENAVEKAIHARACTPDLGGKLSTSQVADYMLEQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WKB3</accession>
    <name>A0A0P6WKB3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GGDEF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_19165</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_19165"/>
    <dbReference type="EnsemblBacteria" id="KPL70152">
        <property type="protein sequence ID" value="KPL70152"/>
        <property type="gene ID" value="ADN00_19165"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGDEF" evidence="1">
        <location>
            <begin position="189"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="322" mass="36268" checksum="EE84C796FCEF8781" modified="2016-01-20" version="1">MLIKMGELLKRCLTLEDVFSVFAQYGGEFFPQSVGGLYIFHPETGLSDLVAQWGKGLTKQMVFTFEDCSAIRQNSPCIEVVQPEEVRCEHVRMAMEEGGFNPYICAPLNYQGEVLGLLHLRFESADALKEHVNLAVVLADLLSLVMINMRLREQLELQTVIDPLTGLFNRRYLLETINRNIFHPERREYPVSVLKIDIDGFRTINDQYGFAAGDAILRSVGEFLKGHVRGSDIACRYGGEEFVIILPGLPQEAALKRVEWLRTEVKKLRVRYQGNQLPALTFSIGVALFPQNGSNMTDVLKSANTAMLNAKLQGYDQYALAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WN81</accession>
    <name>A0A0P6WN81_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Flagellar hook-basal body complex protein FliE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">fliE</name>
        <name evidence="5" type="ORF">ADN00_17045</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 3">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the FliE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17045"/>
    <dbReference type="EnsemblBacteria" id="KPL71487">
        <property type="protein sequence ID" value="KPL71487"/>
        <property type="gene ID" value="ADN00_17045"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.471"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00724">
        <property type="entry name" value="FliE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001624">
        <property type="entry name" value="FliE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34653">
        <property type="entry name" value="PTHR34653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02049">
        <property type="entry name" value="FliE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01006">
        <property type="entry name" value="FLGHOOKFLIE"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00205">
        <property type="entry name" value="fliE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL71487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="87" mass="9616" checksum="8A7BB20B4E6B6E15" modified="2016-01-20" version="1">MSNTASAASAPKSETQPLEKTFGDILKGLTASENNANDMVQKLAMGEDVELHDVMLAVEENDVNFRVAMAIRDRLVEAYQEVMRMNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WPS3</accession>
    <name>A0A0P6WPS3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Pyruvate phosphate dikinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_16490</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064139.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16490"/>
    <dbReference type="EnsemblBacteria" id="KPL72072">
        <property type="protein sequence ID" value="KPL72072"/>
        <property type="gene ID" value="ADN00_16490"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3740"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008279">
        <property type="entry name" value="PEP-util_enz_mobile_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036637">
        <property type="entry name" value="Phosphohistidine_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002192">
        <property type="entry name" value="PPDK_AMP/ATP-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00391">
        <property type="entry name" value="PEP-utilizers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01326">
        <property type="entry name" value="PPDK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52009">
        <property type="entry name" value="SSF52009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PPDK_N" evidence="2">
        <location>
            <begin position="18"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers" evidence="1">
        <location>
            <begin position="781"/>
            <end position="852"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL72072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="858" mass="93797" checksum="27984519317F279F" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WQU4</accession>
    <name>A0A0P6WQU4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Chaperone protein DnaK</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">HSP70</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Heat shock 70 kDa protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Heat shock protein 70</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 10" type="primary">dnaK</name>
        <name evidence="10" type="ORF">ADN00_17625</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Acts as a chaperone.</text>
    </comment>
    <comment type="induction">
        <text evidence="6">By stress conditions e.g. heat shock.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000042">
        <property type="protein sequence ID" value="KPL71219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064368.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000042.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17625"/>
    <dbReference type="EnsemblBacteria" id="KPL71219">
        <property type="protein sequence ID" value="KPL71219"/>
        <property type="gene ID" value="ADN00_17625"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2789"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00332">
        <property type="entry name" value="DnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012725">
        <property type="entry name" value="Chaperone_DnaK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029048">
        <property type="entry name" value="HSP70_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="PTHR19375"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="SSF100920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100934">
        <property type="entry name" value="SSF100934"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02350">
        <property type="entry name" value="prok_dnaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00297">
        <property type="entry name" value="HSP70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword evidence="4 6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="595"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="244"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphothreonine; by autocatalysis" evidence="6">
        <location>
            <position position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL71219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="630" mass="68175" checksum="C14FA2D5109C592D" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WTJ4</accession>
    <name>A0A0P6WTJ4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_14565</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000035">
        <property type="protein sequence ID" value="KPL73563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063761.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000035.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL73563">
        <property type="protein sequence ID" value="KPL73563"/>
        <property type="gene ID" value="ADN00_14565"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022791">
        <property type="entry name" value="L-PG_synthase/AglD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03706">
        <property type="entry name" value="LPG_synthase_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00374">
        <property type="entry name" value="TIGR00374"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="78"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="113"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="240"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="269"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="304"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL73563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="336" mass="36808" checksum="F632650AD136EE94" modified="2016-01-20" version="1">MKKFIIAILFLLAIIFVFSRFTEVTEMVDILQRAQPEYLALALLAEGLWLLNVGLAYRVNYRLLDMDKPLKHMVLMSAAANNFVGIIAPSGGMSALAVFLGDAKRNEHSSARVTVACLLYLLFDYIGLLGAVLLGLLVLVRRNRLDWAEITAASILALVALAILMVLYVGFKRPERLGKSLAWLAKKANWLAGKFKRKKRLDVAEAYSFAEDISAGVAVLRANPRQLVIPVILGMTNKGLLITVLLMLFLAFGVPVSGGTVIGGFALGYLFTIVSLTPSGIGMMEGVMALVLRSLGVNLEEAAILTLAFRAITFWLPFIIGMAAFRFLFKEPRTEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WTL6</accession>
    <name>A0A0P6WTL6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_14720</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000035">
        <property type="protein sequence ID" value="KPL73590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063791.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000035.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14720"/>
    <dbReference type="EnsemblBacteria" id="KPL73590">
        <property type="protein sequence ID" value="KPL73590"/>
        <property type="gene ID" value="ADN00_14720"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="9"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="76"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL73590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="138" mass="15666" checksum="AA55D87D6689E751" modified="2016-01-20" version="1">MDFSVQHWMVDMIVFIDPESTVEEALAMMRRRYIHSLIVKKSSADDDYGIITSTDISDKIIAEEVNPCDIKVKDIMHKPLITIEKGRSLKDCAKLMKKHHIHHLPVVDEKNVLIGMISATDFLVAAEAMCQKPGEFLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WY21</accession>
    <name>A0A0P6WY21_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_14705</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000035">
        <property type="protein sequence ID" value="KPL73587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063788.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000035.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14705"/>
    <dbReference type="EnsemblBacteria" id="KPL73587">
        <property type="protein sequence ID" value="KPL73587"/>
        <property type="gene ID" value="ADN00_14705"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="SSF54106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="SSF55797"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132702" description="LysM domain-containing protein" evidence="3">
        <location>
            <begin position="33"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="299"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="4">
        <location>
            <begin position="193"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="248"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL73587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="322" mass="33864" checksum="E9D61022537E8E6B" modified="2016-01-20" version="1">MMKIDSTKTFLLRVLILIMVLSAALPALPVQAQAGSAYDLIAEVNALRAEYGLQPYQVDGGLMASAQAHSEYQASIQTGTHTRADGSSPASLGFTENIAYGGSMSVSYAVRSIWSDQLHMNTMVGYESGYVGAGVATDASGNVYYTLQVRSTGGYVPPVIQSTPVGGGAPVAVSTPQVVKVELTNTPNPDGSIKHKVEPGQTIWAIALAYGISEVELIQFNYLDAQNPLIYPGQVIIVQPAYTPTVTPTITNTLPPPTRTPRPTFTPRPTRPTATLAHTATPTNPPLVPPLNTASRRGIGIGIILVCAAGLALSILPSVLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WYD1</accession>
    <name>A0A0P6WYD1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphate transport system permease protein PstA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_17490</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064337.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17490"/>
    <dbReference type="EnsemblBacteria" id="KPL71473">
        <property type="protein sequence ID" value="KPL71473"/>
        <property type="gene ID" value="ADN00_17490"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.565"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035435">
        <property type="term" value="P:phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005672">
        <property type="entry name" value="Phosphate_PstA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00974">
        <property type="entry name" value="3a0107s02c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="16"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="65"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="106"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="140"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="184"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="256"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="7">
        <location>
            <begin position="69"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL71473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="288" mass="31237" checksum="82F74562D9A16760" modified="2016-01-20" version="1">MDSKYDSSSSRQKEKIGFAALTAISTLTVLPIIAILIYILIQGMPVINWEFITGLPREGMRAGGIFPAIVGTFYLTIGTALFSIPPGIAAAIYLSEYAGDNRWTRAIRIAMVNLAGIPSVVYGLFGLGVFVIFLQFGTSILAASLTLSIMTLPVIISTAEEAMRAVPQSFRLISVSVGATKWQTIWKIVLPQSLPGIITGIILGLQRAAGETAPILFTGAAFFLPQLPKSPLDATMALPYHLFVISTQVPGMPIQIQYGTVLVLLFFVLSMEIMATLIRSRARARRQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZ85</accession>
    <name>A0A0P6WZ85_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PadR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_16225</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064088.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72031">
        <property type="protein sequence ID" value="KPL72031"/>
        <property type="gene ID" value="ADN00_16225"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005149">
        <property type="entry name" value="Tscrpt_reg_PadR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03551">
        <property type="entry name" value="PadR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PadR" evidence="1">
        <location>
            <begin position="15"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="182" mass="21058" checksum="D834B3A1A7E366B2" modified="2016-01-20" version="1">MSPLTRTPLTIEHALLGFLLNGAMHGYDIHRQMMNPQGLGQVWQVKQSQLYALLNRLEQEGFVTTALEAQDSRPPRKMFSLTETGWQTFLQWTSAPVPHGRDMRLDFIVKLYFARQISQNAAEKLIEMQRETCQLWQMDRGDNSPGTFEWLISEFRRGQIAAMLAWLDQCQRFILHCDSEGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZL2</accession>
    <name>A0A0P6WZL2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_15700</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063977.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72260">
        <property type="protein sequence ID" value="KPL72260"/>
        <property type="gene ID" value="ADN00_15700"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="144" mass="15762" checksum="3F3933C463132AC4" modified="2016-01-20" version="1">MTVVNRKDVRSALAAYLQASVTKAQAVYPYQVADFNGASPVVYITSSGSARDKLTGLGLNSNFVLNIHIFVLYPKKPDQSYSEQTAENLLDDLEQEVATACLNIKNHSLIKAIMYDQPSNADGMAEIAGETYLHEIISVNVNCF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X2D6</accession>
    <name>A0A0P6X2D6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_14310</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000034">
        <property type="protein sequence ID" value="KPL73741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL73741">
        <property type="protein sequence ID" value="KPL73741"/>
        <property type="gene ID" value="ADN00_14310"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL73741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="337" mass="38206" checksum="F700E654F6343555" modified="2016-01-20" version="1">MFETLPPQDERVYSFFDLSSGKATEIPGRNYSYLSVSPDRSMYAYKNWDENQLEVYGSDGKIIRKLPWKQNWGSIDGWIDNQHLIIVMAVIDVPGFVKYPRAITILNPLENKEKILEPNYPNIDIGNTNVNWPYMGTTVYNPSLSRVVYPGSLENSPSGGYQGFILYGIPEKAVLAEFDNPYWSGEGPYWSLDGSHLLLLVNREFYIVSPDGIPEVITQMNPLEGKRNYTAEFYSWSPDNKTVAFRLLSYETEEFSLAFLDTKTGMITNTCILAGFEPDYYTTFPYPIWSKDGKSLVIAANYQKDPPGNDVVLVNLAEKSAFIIAKNLSPVGWVENP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-02-26" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X2F2</accession>
    <name>A0A0P6X2F2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_14555</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000035">
        <property type="protein sequence ID" value="KPL73561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063759.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000035.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL73561">
        <property type="protein sequence ID" value="KPL73561"/>
        <property type="gene ID" value="ADN00_14555"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL73561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="211" mass="22035" checksum="97F11B6FEFD71787" modified="2016-01-20" version="1">MSEVFLINSIRAESGEPVEMLEARLYAQAQIRRGWLEQADIIGATAAARQVGGPFVRSWPAESGLQHFLLQQAARTLLAGDAHLAAVVEAGAGAALLASPEAVGVYNLSPRAALLARLGLPNGADLAALLKRRKLELEEGLVCAAAELSAEQAQRLAAALPGGAALPQAQEGFWQALDTLLEKMSAQHPPAKGVLASAWQAGALLTLLEPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X368</accession>
    <name>A0A0P6X368_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ABC transmembrane type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_09120</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062685.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09120"/>
    <dbReference type="EnsemblBacteria" id="KPL77284">
        <property type="protein sequence ID" value="KPL77284"/>
        <property type="gene ID" value="ADN00_09120"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4058"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="52"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="148"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="190"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="248"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="297"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="350"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="111"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL77284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="384" mass="43314" checksum="C984E6520DC28016" modified="2016-01-20" version="1">MIENPYLDALLTAVAAIIFIIISSFGLGALARLVAKLFGASQRKQQNTFAGYLFAAPWIVGFLIFVIIPLGFSIYWSFTDYRVVSNEPANWIGLENYAQLILKDSGFRASIVNTLYLTFIGLPLQMGFALLLAVLLNEKLPGQKVFRMAFYLPVILGFNTAVLLAWRLMLNTGTGIINQLIRAITTAIPALGYVNRALVFVVELSSAFFLGISNGKFNLLTKVWETGFPAANRVPLWVQSPLWSKMSVVLLMIWGCGAMMLIFLAGLKNIPRELHEAAEVDGATAWRRFWKISFPLLTPYIFYNLVVGLINSLQIFEPIFVLYRDNQPLVPSAISMVYYLWQASFRHFEIGYGSAISWLILIIILIVTAIQFKMQDRWVTYDLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X3X1</accession>
    <name>A0A0P6X3X1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063647.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000033.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13980"/>
    <dbReference type="EnsemblBacteria" id="KPL74110">
        <property type="protein sequence ID" value="KPL74110"/>
        <property type="gene ID" value="ADN00_13980"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="87"/>
            <end position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="304" mass="32391" checksum="03DEC4D090E8A553" modified="2016-01-20" version="1">MCTSNPNTKTNPPSLNLKRLLPRALFAFCAAWVILAAGLSAVYTRGLLHPACAPAGDPPAGFASVRLQTQDDVALQGWWAAPHNGAVILLLPGHGGSRASLLEEARFLSAAGYGVLSVDPRSCAGEKSTIGWREAQDLRAMRDYALAQPGVQWLGVLGFSAGGAAAILAAAEMPEIRAVIAEGNYANLAAEITFTPAFPLSMEWLIQRFTLLTYTLQTGVWPGRVSPIEALPRGCPRPVLLIHGQREIERSRGEQQAAAAPCAQLWVVPAAGHGEYAAAQPQLYRQTVLQFLAQARQTVDVPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5F3</accession>
    <name>A0A0P6X5F3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Acetolactate synthase small subunit</fullName>
            <shortName evidence="8">AHAS</shortName>
            <shortName evidence="8">ALS</shortName>
            <ecNumber evidence="8">2.2.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Acetohydroxy-acid synthase small subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ADN00_19090</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the conversion of 2 pyruvate molecules into acetolactate in the first common step of the biosynthetic pathway of the branched-amino acids such as leucine, isoleucine, and valine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>H(+) + 2 pyruvate = (2S)-2-acetolactate + CO2</text>
            <dbReference type="Rhea" id="RHEA:25249"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58476"/>
            <dbReference type="EC" id="2.2.1.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 8">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 1/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 8">Dimer of large and small chains.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 8">Belongs to the acetolactate synthase small subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.6" evidence="8"/>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064634.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_19090"/>
    <dbReference type="EnsemblBacteria" id="KPL70141">
        <property type="protein sequence ID" value="KPL70141"/>
        <property type="gene ID" value="ADN00_19090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3131"/>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00055"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00059"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003984">
        <property type="term" value="F:acetolactate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990610">
        <property type="term" value="F:acetolactate synthase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04878">
        <property type="entry name" value="ACT_AHAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004789">
        <property type="entry name" value="Acetalactate_synth_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027271">
        <property type="entry name" value="Acetolactate_synth/TF_NikR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019455">
        <property type="entry name" value="Acetolactate_synth_ssu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039557">
        <property type="entry name" value="AHAS_ACT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30239">
        <property type="entry name" value="PTHR30239"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10369">
        <property type="entry name" value="ALS_ss_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00119">
        <property type="entry name" value="acolac_sm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACT" evidence="9">
        <location>
            <begin position="4"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU368092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL70141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="182" mass="20177" checksum="00842C292C9489A4" modified="2016-01-20" version="1">MQHTLVALVEDKPGVLNRVASLFRRRAFNIESLTVGHTDCPGVSRMTIVVDSNEVSTEQVVNNLYKLVNTLHVTDLAATPSVQRDLALIKVRSEAATRTEIMQLVDVYRARIVDVANDSMIVEITGVEEKINSFVDVLKPFGIVEMVRTGIVAMARGSNANPEFNLHTVQNDSSYVSQEYCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5I3</accession>
    <name>A0A0P6X5I3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_07645</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062387.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07645"/>
    <dbReference type="EnsemblBacteria" id="KPL78317">
        <property type="protein sequence ID" value="KPL78317"/>
        <property type="gene ID" value="ADN00_07645"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3359"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="SNARE_assoc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="SNARE_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="213" mass="23709" checksum="F67A010A78200CCB" modified="2016-01-20" version="1">MNLGQILDAIKIWAESVISSLGYPGLTLVMFLENLFPPIPSEIVLPLAGSLTLTGRFSILGVVLWGMLGSLAGALVFYALGKLLGEERVRWLIDKFGKYLTISNEDFDRSLRWFDRYGDWVIFFGRMVPIVRSLISIPAGLASMNMVKFLFFTVLGTSLWNFVLSFAGRLLGASWPVVAEWIGVYQNVVIVVCGIAVVLFIAIRWRKQVTAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5U1</accession>
    <name>A0A0P6X5U1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062681.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77280">
        <property type="protein sequence ID" value="KPL77280"/>
        <property type="gene ID" value="ADN00_09090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="153" mass="17142" checksum="D5B52F25DA14F616" modified="2016-01-20" version="1">MSQQEKTIAVSFMSHILILGYFLINLFQMMRNGELVATRIFALWALVIVTLIIVNIIGNILTNILLAIFHAVKTQRAEEPPASEFIEDERDKLISLKGTRVTYITFSFGVLAAMLTFAFGQPPLVMFSLLILSSIVAEIAGDISQMVLYRRGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5Z3</accession>
    <name>A0A0P6X5Z3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_09295</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77363">
        <property type="protein sequence ID" value="KPL77363"/>
        <property type="gene ID" value="ADN00_09295"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4093"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029465">
        <property type="entry name" value="ATPgrasp_TupA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14305">
        <property type="entry name" value="ATPgrasp_TupA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL77363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="271" mass="32515" checksum="B7ED7E852FCCB482" modified="2016-01-20" version="1">MPSYPKYFIRSWYLHRFKKPVNLNSPVTFNEKIQWLKLYGGYDRYSQFVDKLAVKEFVKKTVGSHYTIENKQYIDVNQGIILSNLPDHFVIKPTHTSGDVFICREKSLVNSEQLKQLINTWYELDYYFQWFECVYKNLRPGVIVEEFLDDGNGDLRDFKFYCFDGRVEYIHVDLDRFHRHSRNVYSRDWELQTFSYEYPYSGINIPAPEKLDEMINVAETLSKGFPFLRVDLYYLQNKKIKFGELTFFPGAGFERFYPAIWDTKFGEMLHI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X6B4</accession>
    <name>A0A0P6X6B4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Tad domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_06585</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000017">
        <property type="protein sequence ID" value="KPL78582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78582">
        <property type="protein sequence ID" value="KPL78582"/>
        <property type="gene ID" value="ADN00_06585"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028087">
        <property type="entry name" value="Tad_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13400">
        <property type="entry name" value="Tad"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tad" evidence="1">
        <location>
            <begin position="2"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="600" mass="65257" checksum="A011DF910DA01E68" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X6R9</accession>
    <name>A0A0P6X6R9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ADN00_05825</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05825"/>
    <dbReference type="EnsemblBacteria" id="KPL78756">
        <property type="protein sequence ID" value="KPL78756"/>
        <property type="gene ID" value="ADN00_05825"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1641"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="139"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="9">
        <location>
            <begin position="161"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="8">
        <location>
            <begin position="221"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="194"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL78756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="439" mass="47743" checksum="E07FE54527F485F5" modified="2016-01-20" version="1">MLYVLETRLLLPMVYRNLEKDATLMAEITRNQPVFWQYGEAAQALVDGVSPYLSGSLSILTTNGNLLATSRAPAGDLSGEVVELPDMKAVRQGQTIQLKRGTLAEVFAPVYDLNNRMIGVVRMTTQVVTVTDEVYQLRYILGGVLLLGVLAGVGFGSYLAISINKPIQRVSRSIRELANGNWQTHLEVEGPEELQALSQEVNLLVDRLQNLEKTRQQLLSNLVHELGRPLGALHSASQALLKGADKDAELAKDLLTGMDSEIGRLQMLLNDLAGLHDQTLGRMDLKRKPVEIADWLATVLSPWRAEADTKGVRWQVSVPTDLPAVEMDPDRMAQAVGNLLSNAIKFTPAGGAIRVETSVNSGWLEIGVADSGPGIAAEEQEKIFQPFYHGAQNRRVVEGMGLGLSIARDIVQAHGGEIKLTSAPGQGSCFMLRIPIQSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X6T8</accession>
    <name>A0A0P6X6T8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Ribonuclease PH</fullName>
            <shortName evidence="4">RNase PH</shortName>
            <ecNumber evidence="4">2.7.7.56</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">tRNA nucleotidyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rph</name>
        <name evidence="7" type="ORF">ADN00_05945</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>phosphate + tRNA(n+1) = a ribonucleoside 5'-diphosphate + tRNA(n)</text>
            <dbReference type="Rhea" id="RHEA:10628"/>
            <dbReference type="Rhea" id="RHEA-COMP:17343"/>
            <dbReference type="Rhea" id="RHEA-COMP:17344"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:173114"/>
            <dbReference type="EC" id="2.7.7.56"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homohexameric ring arranged as a trimer of dimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RNase PH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.56" evidence="4"/>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062050.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05945"/>
    <dbReference type="EnsemblBacteria" id="KPL78774">
        <property type="protein sequence ID" value="KPL78774"/>
        <property type="gene ID" value="ADN00_05945"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1666"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-exoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009022">
        <property type="term" value="F:tRNA nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd11362">
        <property type="entry name" value="RNase_PH_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00564">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015847">
        <property type="entry name" value="ExoRNase_PH_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036345">
        <property type="entry name" value="ExoRNase_PH_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002381">
        <property type="entry name" value="RNase_PH_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018336">
        <property type="entry name" value="RNase_PH_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03725">
        <property type="entry name" value="RNase_PH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55666">
        <property type="entry name" value="SSF55666"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01966">
        <property type="entry name" value="RNasePH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01277">
        <property type="entry name" value="RIBONUCLEASE_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 4" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 4" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="2 4" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="RNase_PH" evidence="5">
        <location>
            <begin position="15"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="RNase_PH_C" evidence="6">
        <location>
            <begin position="161"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphate (substrate) binding" evidence="4">
        <location>
            <begin position="127"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <note>substrate</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL78774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="241" mass="26325" checksum="CCE01DEAC7D6B99B" modified="2016-01-20" version="1">MPEQKVRLDGRRPDELRPLCFTTDYVDYPHGSVLVEMGKTRVLCNVCVEEKVPDWMAGRGVGWLTAEYSMLPQSTQKRNPRETNGLKGRTQEIRRLIGRSLRAAVDLSQIGERTLLIDCDVIQADGGTRTASINGSYVALAIAVNKLTAQGLLPASALLPPVAAVSVGMVNGYACLDLNYGEDSSAEVDLNVVMTADGKFIEVQGTAEKEPYDRRSLNAMLDLAEQGIREILILQQAAIYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X709</accession>
    <name>A0A0P6X709_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">tRNA(Ile)-lysidine synthase</fullName>
            <ecNumber evidence="7">6.3.4.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">tRNA(Ile)-2-lysyl-cytidine synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">tRNA(Ile)-lysidine synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">tilS</name>
        <name evidence="9" type="ORF">ADN00_12220</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + cytidine(34) in tRNA(Ile2) + L-lysine = AMP + diphosphate + H(+) + lysidine(34) in tRNA(Ile2)</text>
            <dbReference type="Rhea" id="RHEA:43744"/>
            <dbReference type="Rhea" id="RHEA-COMP:10625"/>
            <dbReference type="Rhea" id="RHEA-COMP:10670"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="ChEBI" id="CHEBI:83665"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.4.19"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">The N-terminal region contains the highly conserved SGGXDS motif, predicted to be a P-loop motif involved in ATP binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the tRNA(Ile)-lysidine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.19" evidence="7"/>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063297.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12220"/>
    <dbReference type="EnsemblBacteria" id="KPL76100">
        <property type="protein sequence ID" value="KPL76100"/>
        <property type="gene ID" value="ADN00_12220"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3920"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016879">
        <property type="term" value="F:ligase activity, forming carbon-nitrogen bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01992">
        <property type="entry name" value="PP-ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01161">
        <property type="entry name" value="tRNA_Ile_lys_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012796">
        <property type="entry name" value="Lysidine-tRNA-synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011063">
        <property type="entry name" value="TilS/TtcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012094">
        <property type="entry name" value="tRNA_Ile_lys_synt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012795">
        <property type="entry name" value="tRNA_Ile_lys_synt_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43033">
        <property type="entry name" value="PTHR43033"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01171">
        <property type="entry name" value="ATP_bind_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11734">
        <property type="entry name" value="TilS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00977">
        <property type="entry name" value="TilS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02433">
        <property type="entry name" value="lysidine_TilS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02432">
        <property type="entry name" value="lysidine_TilS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TilS_C" evidence="8">
        <location>
            <begin position="417"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="50"/>
            <end position="55"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL76100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="503" mass="55176" checksum="0C73CC22C91D4FB8" modified="2016-01-20" version="1">MKAIADEGAGRGVNGKVRDYNFSMGLEQLEIILEQRCLLSRAQPLVVGFSGGADSTCLLLALLELGYPVIAAHFNHHLRESAAHDAQKAAELAQAAGAVFWLGEADVGRMAREQSLSIEEGARKARYTFLFECARKAGAQAVAVGHHADDQVETVLMNFMRGAGPDGLAGMAYRVVLPEWDETIPVVRPLLAAWRSEIEAFCSERGVEPVEDPTNRDVIYTRNRVRWDLLPFLEKLNPSAREAIWRTADILQADNADLEEADEAAWKEANIISGEGLVVLDWPVLAGFSLGRQRRIIRRALKKLRPGLKDIDYAAIERAVGFLRQPTRSRTMDLIAGIELRLEGSQLILCTAESVLPDSGLRLPAGEAARPLSVPGEVALEGGAYLRSAWRDPGTGSARPASELEAWFDGDALQLPLLVRTRLPGDRLQPFGMGGQSQKLSDLMVNEKIAARLRGRWPLVCTQDQIVWVPGVRRSQCAQVTAKSKRILHLWIEADQSCKASSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7E3</accession>
    <name>A0A0P6X7E3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_08280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062515.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77865">
        <property type="protein sequence ID" value="KPL77865"/>
        <property type="gene ID" value="ADN00_08280"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="150"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="353" mass="38389" checksum="BE9A07098F4E0A6A" modified="2016-01-20" version="1">MEKIREYLKNPLITAAAGFVVGLIIGWMVLGWGLFPVKWTDASAGQLRADVREDYLKMAIQSYSLNKDATLALTRWNELGDAAPEVFKKVQLDPSMNAEAVALFSNVVQAPMQEPLPAVPGEGVTQAVPLPLETQVVPATEEKEGGIKPVLLLGVFCLLTLIIGGAAAYVLLIRKRPARSGASYAPVQQSQEINRTTEVTDYESEGQSAPIQQFMTTYMLGDDLYDDSFSIDSTSGEFLGECGVGITETIGVGDPKKVTAFEVWLFDKTDIQTVTKVLMSEHAFNDPSINQKLASKGDPVMIAPGERVLLETAALQLEARVVDMNYGQGALPENSFFDRLTLELAIWPKGSRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X8G0</accession>
    <name>A0A0P6X8G0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PTS_IIB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_11515</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11515"/>
    <dbReference type="EnsemblBacteria" id="KPL76575">
        <property type="protein sequence ID" value="KPL76575"/>
        <property type="gene ID" value="ADN00_11515"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008982">
        <property type="term" value="F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036095">
        <property type="entry name" value="PTS_EIIB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003501">
        <property type="entry name" value="PTS_EIIB_2/3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02302">
        <property type="entry name" value="PTS_IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52794">
        <property type="entry name" value="SSF52794"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132913" description="PTS_IIB domain-containing protein" evidence="2">
        <location>
            <begin position="22"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="PTS_IIB" evidence="3">
        <location>
            <begin position="6"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL76575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="100" mass="10806" checksum="B433471B6B680F73" modified="2016-01-20" version="1">MNRPAVILVMCGSSIATSSLAAVKIEDEARRRKVKVTVKKGKVSDTDVLIQTVHPDIIVATAQIKPREDVLVFSGVPLLTGIGQDKLYNDLFDAIAKMAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X992</accession>
    <name>A0A0P6X992_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PTS EIIA type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061920.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05230"/>
    <dbReference type="EnsemblBacteria" id="KPL78661">
        <property type="protein sequence ID" value="KPL78661"/>
        <property type="gene ID" value="ADN00_05230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008982">
        <property type="term" value="F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00211">
        <property type="entry name" value="PTS_IIA_fru"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016152">
        <property type="entry name" value="PTrfase/Anion_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002178">
        <property type="entry name" value="PTS_EIIA_type-2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004715">
        <property type="entry name" value="PTS_IIA_fruc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00359">
        <property type="entry name" value="PTS_EIIA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55804">
        <property type="entry name" value="SSF55804"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00848">
        <property type="entry name" value="fruA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51094">
        <property type="entry name" value="PTS_EIIA_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PTS EIIA type-2" evidence="1">
        <location>
            <begin position="10"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="163" mass="18047" checksum="BD6EA3D54F110038" modified="2016-01-20" version="1">MSYEHLNIVEVIRPDTVDLDLKGITCKEEAIHYLAGLLNEAGLINDKDAYIQSVYERESLGPTYMENFIAIPHGKCAAVREAGIAFGRSPEGFEYLTQDGGGLAKLVFLLAIPERTAPDAYIAVLAQLARLLVHDEFRAKLMEAKCYQDVFEAIAEGQVLLED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9P2</accession>
    <name>A0A0P6X9P2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Adenine DNA glycosylase</fullName>
            <ecNumber evidence="4">3.2.2.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">ADN00_17600</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolyzes free adenine bases from 7,8-dihydro-8-oxoguanine:adenine mismatched double-stranded DNA, leaving an apurinic site.</text>
            <dbReference type="EC" id="3.2.2.31"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Nth/MutY family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.31" evidence="4"/>
    <dbReference type="EMBL" id="LGCL01000042">
        <property type="protein sequence ID" value="KPL71214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064363.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000042.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17600"/>
    <dbReference type="EnsemblBacteria" id="KPL71214">
        <property type="protein sequence ID" value="KPL71214"/>
        <property type="gene ID" value="ADN00_17600"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2783"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000701">
        <property type="term" value="F:purine-specific mismatch base pair DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005760">
        <property type="entry name" value="A/G_AdeGlyc_MutY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004036">
        <property type="entry name" value="Endonuclease-III-like_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003651">
        <property type="entry name" value="Endonuclease3_FeS-loop_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000445">
        <property type="entry name" value="HhH_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044298">
        <property type="entry name" value="MIG/MutY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029119">
        <property type="entry name" value="MutY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42944">
        <property type="entry name" value="PTHR42944"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00633">
        <property type="entry name" value="HHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14815">
        <property type="entry name" value="NUDIX_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00525">
        <property type="entry name" value="FES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="SSF48150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01084">
        <property type="entry name" value="mutY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01155">
        <property type="entry name" value="ENDONUCLEASE_III_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="12" id="KW-0234">DNA repair</keyword>
    <keyword evidence="13" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="14">
        <location>
            <begin position="227"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KPL71214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="358" mass="40281" checksum="CB553CC964159FEA" modified="2016-01-20" version="1">MHKQIASRLLNWYEDAARRLPWRGVSDPYAVWVSEVMLQQTRVETVIPFYERWMRRFPTVQSLAEASEQDVLLAWEGMGYYNRARSLHKAARQVMRDYGGKLPASREALIKLPGIGEYSAGAIASIAFGLDETAVDGNVRRVYARLFDVDTPIKSPEGLERVEQIAREQLPAGLAGDYNQALMDLGAMICLPREPRCEICPLKELCLARQNGTQAERPVKSAKPEIPHWTVTAAVIWKDGKVLLARRPLNGLLGGMWEFPGGKLEAGESLKDCLKREIVEELDAPIEVGEAFGVYKHAYTHFKVTLHAFACRFVSEEPDVDGAEFVVWAAPEELQNYPMGKIDRDIARRIVSERSAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XA15</accession>
    <name>A0A0P6XA15_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_15980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL71997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064040.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL71997">
        <property type="protein sequence ID" value="KPL71997"/>
        <property type="gene ID" value="ADN00_15980"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="208"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="278"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="307"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="338"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="370"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="433"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="466"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL71997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="628" mass="71204" checksum="0A4B242F563ACE2B" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XA16</accession>
    <name>A0A0P6XA16_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Flagellar FliJ protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">ADN00_17070</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FliJ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064260.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL71406">
        <property type="protein sequence ID" value="KPL71406"/>
        <property type="gene ID" value="ADN00_17070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009288">
        <property type="term" value="C:bacterial-type flagellum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044781">
        <property type="term" value="P:bacterial-type flagellum organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012823">
        <property type="entry name" value="Flagell_FliJ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02050">
        <property type="entry name" value="FliJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1005">Bacterial flagellum biogenesis</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="80"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KPL71406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="150" mass="17754" checksum="5C40358687BFBD91" modified="2016-01-20" version="1">MAPKFSLQTVLDVRHSKVEALEIEMGKLQLAQQEKIALEETLQRLKFNLFDQLQDQMVGDMDLVLIEQLRGNIDQVEEGIQITRQVIEELGKRIEAKRRELVAARQDEETLDILKRKEQDRFAAEMRRKENNLQDDLYISRIYRMRNQSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XA71</accession>
    <name>A0A0P6XA71_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphate-binding protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_17480</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in the system for phosphate transport across the cytoplasmic membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the PstS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064335.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17480"/>
    <dbReference type="EnsemblBacteria" id="KPL71497">
        <property type="protein sequence ID" value="KPL71497"/>
        <property type="gene ID" value="ADN00_17480"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.563"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042301">
        <property type="term" value="F:phosphate ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024370">
        <property type="entry name" value="PBP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011862">
        <property type="entry name" value="Phos-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12849">
        <property type="entry name" value="PBP_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02136">
        <property type="entry name" value="ptsS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0732">Signal</keyword>
    <keyword evidence="2 4" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5027165138" description="Phosphate-binding protein" evidence="4">
        <location>
            <begin position="28"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="PBP_domain" evidence="5">
        <location>
            <begin position="31"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL71497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="301" mass="32551" checksum="345FA7C7D48CDC27" modified="2016-01-20" version="1">MRRYFYLTALMVALALTGCQSTSSPEAQEIPQSSTYIENKGSDTMVNLALVWAESYQASNPDVRISVTGGGSGTGLAALVNGTVDVANASRQIKPEEQDQIAQSGHQAVEYVVASDAIAVIVNPSNPIQNLTLEEISRIYKGEINNWAELGGENRPIVRLSRETNSGTHVYFLEEVIRLGSSEDKSIFSADTLLLPSSEGIITEVRDNPNAIGYDGLGYVTPDVKVISVAADRSHSYVLPTIETVKDGSYPISRDLYMYTTESPSQAVQTYLEWVYSAEAQQIVSELGFVPVTPSEGANGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAC6</accession>
    <name>A0A0P6XAC6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_03930</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061660.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79045">
        <property type="protein sequence ID" value="KPL79045"/>
        <property type="gene ID" value="ADN00_03930"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="103"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="146"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="180" mass="18883" checksum="F0B8B5E22B93C7E9" modified="2016-01-20" version="1">MTDEMLNPVAEEPEAAASGQEIPVEAVEAVEAERVEVVEASPAAEAPRAGQAARAGASGKMERPDLLTLTAVYHFLCALPGLFFGCLLLALPVPAILASDARGIGLFAALMGMAVAIFFTGGIGIIYAVVGWGLLKMKSWARWSAIALAILFLPAFPIGTVAGGLLLAYLLQDETRRLFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAM4</accession>
    <name>A0A0P6XAM4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="19">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">ADN00_04815</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>2'-deoxyribonucleotide-(2'-deoxyribose 5'-phosphate)-2'-deoxyribonucleotide-DNA = a 3'-end 2'-deoxyribonucleotide-(2,3-dehydro-2,3-deoxyribose 5'-phosphate)-DNA + a 5'-end 5'-monophospho-2'-deoxyribonucleoside-DNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:66592"/>
            <dbReference type="Rhea" id="RHEA-COMP:13180"/>
            <dbReference type="Rhea" id="RHEA-COMP:16897"/>
            <dbReference type="Rhea" id="RHEA-COMP:17067"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:136412"/>
            <dbReference type="ChEBI" id="CHEBI:157695"/>
            <dbReference type="ChEBI" id="CHEBI:167181"/>
            <dbReference type="EC" id="4.2.99.18"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolysis of DNA containing ring-opened 7-methylguanine residues, releasing 2,6-diamino-4-hydroxy-5-(N-methyl)formamidopyrimidine.</text>
            <dbReference type="EC" id="3.2.2.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FPG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061821.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04815"/>
    <dbReference type="EnsemblBacteria" id="KPL79173">
        <property type="protein sequence ID" value="KPL79173"/>
        <property type="gene ID" value="ADN00_04815"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.329"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140078">
        <property type="term" value="F:class I DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008534">
        <property type="term" value="F:oxidized purine nucleobase lesion DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015886">
        <property type="entry name" value="DNA_glyclase/AP_lyase_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015887">
        <property type="entry name" value="DNA_glyclase_Znf_dom_DNA_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020629">
        <property type="entry name" value="Formamido-pyr_DNA_Glyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012319">
        <property type="entry name" value="FPG_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035937">
        <property type="entry name" value="MutM-like_N-ter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_S13-like_H2TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000214">
        <property type="entry name" value="Znf_DNA_glyclase/AP_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010663">
        <property type="entry name" value="Znf_FPG/IleRS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01149">
        <property type="entry name" value="Fapy_DNA_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06831">
        <property type="entry name" value="H2TH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06827">
        <property type="entry name" value="zf-FPG_IleRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00898">
        <property type="entry name" value="Fapy_DNA_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01232">
        <property type="entry name" value="H2TH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="SSF46946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81624">
        <property type="entry name" value="SSF81624"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00577">
        <property type="entry name" value="fpg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51068">
        <property type="entry name" value="FPG_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01242">
        <property type="entry name" value="ZF_FPG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51066">
        <property type="entry name" value="ZF_FPG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="11" id="KW-0234">DNA repair</keyword>
    <keyword evidence="10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="14" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 16" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FPG_CAT" evidence="18">
        <location>
            <begin position="2"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="FPG-type" evidence="17">
        <location>
            <begin position="242"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00024490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KPL79173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="278" mass="30993" checksum="DBAAD59749262E93" modified="2016-01-20" version="1">MPELPEVETIVCALREGGRGGDALPGQRVGGACILWPRALQSPAVDDFARRIVGQSVRGVERRGKYILLPLTSDTLLLHLRMSGDLRVERSPEGGPLEGLQPHDRALFWFEDGLRLVFNDPRKFGRVWLTADPQDVVGELGPEPFSPTLTVQSFYQRLVSKKRQLKPLLLDQTFLAGLGNIYTDGALHMARLHPLMASDRLTVGQAEVLLNAIRWVLEEGIRRNGASIDWVYRGGDFQNYFRVYQRTGKACPVCGHAVQRMVVGQRGTHYCPVCQPAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBD1</accession>
    <name>A0A0P6XBD1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LMWPc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_16070</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the low molecular weight phosphotyrosine protein phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16070"/>
    <dbReference type="EnsemblBacteria" id="KPL72009">
        <property type="protein sequence ID" value="KPL72009"/>
        <property type="gene ID" value="ADN00_16070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006470">
        <property type="term" value="P:protein dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023485">
        <property type="entry name" value="Ptyr_pPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036196">
        <property type="entry name" value="Ptyr_pPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017867">
        <property type="entry name" value="Tyr_phospatase_low_mol_wt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01451">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00719">
        <property type="entry name" value="LMWPTPASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00226">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52788">
        <property type="entry name" value="SSF52788"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LMWPc" evidence="3">
        <location>
            <begin position="9"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL72009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="166" mass="18616" checksum="A9AF82AED257B4CA" modified="2016-01-20" version="1">MYLMENHPPAVLLVCTANICRSPIAEGLLKALVARQVEGGYFWRIESAGTWTRPGLLAAPFSVQVMAERGIDISNHTSQSIEDVDLSEFDLILTMESGHKEAIRVEFPETRERVLMLKELVNQKTPIADPVGQPIEVFRQTANEIEQTLHQGLPVILQMVSQQRKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBL2</accession>
    <name>A0A0P6XBL2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH tetR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_08780</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000022">
        <property type="protein sequence ID" value="KPL77672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062617.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000022.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77672">
        <property type="protein sequence ID" value="KPL77672"/>
        <property type="gene ID" value="ADN00_08780"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1474"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023772">
        <property type="entry name" value="DNA-bd_HTH_TetR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039536">
        <property type="entry name" value="TetR_C_Proteobacteria"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14246">
        <property type="entry name" value="TetR_C_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01081">
        <property type="entry name" value="HTH_TETR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="11"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="194" mass="22251" checksum="E80744A3E070E0C8" modified="2016-01-20" version="1">MKPCTPPGALNENARLILDIAWPLFQQKGYRGLSLDELCERCGLTKPTLYYYFQSKENLYLQVLKRQIDGYHTAISDETLTTPQRLENLAAIMLEQMNSNWLAMLRDLEHFKNPENLTQIRAIFARDLLQPLANLMENAAQQGELRSDDPELLAWSFLGLVSTFTGRLALFDQDAQAGARWLVNFFMQGARQTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBN0</accession>
    <name>A0A0P6XBN0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_08840</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000022">
        <property type="protein sequence ID" value="KPL77681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062628.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000022.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77681">
        <property type="protein sequence ID" value="KPL77681"/>
        <property type="gene ID" value="ADN00_08840"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL77681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="195" mass="22306" checksum="59801CFC8FCD1F1F" modified="2016-01-20" version="1">MDAGEGYEAILRALQSPARERYARLLELHRETLARYTEAVKRIDARAAARASSDGRTMAQVVAHIADWERYFILAAGELAAGVAWPQFMELKGYLEEDGRCLQFESVDDFNAYSARRAAGWPWERIQRMALRAAEVLYALYTNAEILPIETLDASRMYDTEEFGFPLSIPVGWYLWAIAIGHELEEHAQDLQMWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XC63</accession>
    <name>A0A0P6XC63_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_08100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062569.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08100"/>
    <dbReference type="EnsemblBacteria" id="KPL77837">
        <property type="protein sequence ID" value="KPL77837"/>
        <property type="gene ID" value="ADN00_08100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.620"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004061">
        <property type="term" value="F:arylformamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019441">
        <property type="term" value="P:tryptophan catabolic process to kynurenine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007325">
        <property type="entry name" value="KFase/CYL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037175">
        <property type="entry name" value="KFase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31118">
        <property type="entry name" value="PTHR31118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04199">
        <property type="entry name" value="Cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102198">
        <property type="entry name" value="SSF102198"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL77837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="212" mass="22667" checksum="8C4C000BFA0FFD56" modified="2016-01-20" version="1">MAKFYDVSLSIQPGMPVWPGDPLVSLDLISRIEDGENANVSRMSMGVHTGTHVDAPFHFVAGAATVESLALDVLIGIAQVIEIDRAVGQITADVLRGATINPGVRRVLFKTRNSDLWARGETRFQKDFVALSEDAALFLVDAGIQLVGIDYLSIAPFDAGVPTHVALLTRGVVIVEGVNLAEVPAGMYRMICLPMKLKAADGAPARMVLEAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XC86</accession>
    <name>A0A0P6XC86_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_08210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062504.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77855">
        <property type="protein sequence ID" value="KPL77855"/>
        <property type="gene ID" value="ADN00_08210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="186"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="224"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="254"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="285"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="360"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="389"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="413"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="445"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="494"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="545"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="570"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="599"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="631"/>
            <end position="650"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="769" mass="85198" checksum="925F90311995D4A8" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XCD1</accession>
    <name>A0A0P6XCD1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_01560</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061203.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01560"/>
    <dbReference type="EnsemblBacteria" id="KPL80557">
        <property type="protein sequence ID" value="KPL80557"/>
        <property type="gene ID" value="ADN00_01560"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1069"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001434">
        <property type="entry name" value="DUF11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005754">
        <property type="entry name" value="Sortase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023365">
        <property type="entry name" value="Sortase_dom-sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01345">
        <property type="entry name" value="DUF11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04203">
        <property type="entry name" value="Sortase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63817">
        <property type="entry name" value="SSF63817"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01451">
        <property type="entry name" value="B_ant_repeat"/>
        <property type="match status" value="8"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132979" description="DUF11 domain-containing protein" evidence="3">
        <location>
            <begin position="29"/>
            <end position="2682"/>
        </location>
    </feature>
    <feature type="domain" description="DUF11" evidence="4">
        <location>
            <begin position="1131"/>
            <end position="1239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1912"/>
            <end position="1934"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2022"/>
            <end position="2042"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2279"/>
            <end position="2322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="2281"/>
            <end position="2302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL80557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="2682" mass="272346" checksum="16F8BC1926E1BEBC" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XCY2</accession>
    <name>A0A0P6XCY2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_14945</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000036">
        <property type="protein sequence ID" value="KPL73085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063836.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000036.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL73085">
        <property type="protein sequence ID" value="KPL73085"/>
        <property type="gene ID" value="ADN00_14945"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="298"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="327"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL73085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="369" mass="40942" checksum="160F1004C410CBE6" modified="2016-01-20" version="1">MNQEIAPNTIQEMWGLPLETVVCHACSRAFLKPAGSAADNCPQCSQGRLQPFSGPVRPEPPEKIIPFAISPSHLAARFTRFCEGVWLSAPDFSPQHLAQRALPIYFPLWLVDAAAQGTWQAEAGFDYQVQSTKEIFTNGEWHTQPIQETRIRWEPRLGKISRSYQNVAVNALTDQEQLSTALGQYDFERAIDFDPAHASSAWLRCPDVLPEQAWPQAEMRLQQVLQTDCQTACSAQHVRNFSVTADYSNQNWTQLLAPAYITYYTSDDNQKILVALNAQSGQLYGPRLASQKRGWKSAGILGGIGLGIVLLAILFFLVAAVFPPISIIASILLITGLLLVAGAVVPAAYPWLWNRGQMELRVFRSKDSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDM1</accession>
    <name>A0A0P6XDM1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Lactamase_B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_00680</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the metallo-beta-lactamase superfamily. Type III sulfatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061024.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL81078">
        <property type="protein sequence ID" value="KPL81078"/>
        <property type="gene ID" value="ADN00_00680"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018741">
        <property type="term" value="F:alkyl sulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018909">
        <property type="term" value="P:dodecyl sulfate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07710">
        <property type="entry name" value="arylsulfatase_Sdsa1-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038536">
        <property type="entry name" value="Alkyl/aryl-sulf_dimr_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029229">
        <property type="entry name" value="Alkyl_sulf_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029228">
        <property type="entry name" value="Alkyl_sulf_dimr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044097">
        <property type="entry name" value="Bds1/SdsA1_MBL-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036527">
        <property type="entry name" value="SCP2_sterol-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14864">
        <property type="entry name" value="Alkyl_sulf_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14863">
        <property type="entry name" value="Alkyl_sulf_dimr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55718">
        <property type="entry name" value="SSF55718"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Lactamase_B" evidence="5">
        <location>
            <begin position="57"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00033751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL81078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="589" mass="65268" checksum="BCF1F9BC67D256B4" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDY2</accession>
    <name>A0A0P6XDY2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DinB_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_06770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000018">
        <property type="protein sequence ID" value="KPL78422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062223.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000018.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06770"/>
    <dbReference type="EnsemblBacteria" id="KPL78422">
        <property type="protein sequence ID" value="KPL78422"/>
        <property type="gene ID" value="ADN00_06770"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024775">
        <property type="entry name" value="DinB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12867">
        <property type="entry name" value="DinB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DinB_2" evidence="1">
        <location>
            <begin position="14"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="161" mass="18920" checksum="520666559A9F04D7" modified="2016-01-20" version="1">MTAAMTKKEFLRTLRAQRAQWEALVAYIDARDMLKPGPDGGWSVKDIIAHITWYERETVGMLRARALEGSDWWYLPLDERNQRIHEEVSRLPLDAVLDEADMVFADLLNEVEQLSEADLHDVTRFEGWPSDWVPWKAIASNSYEHYQQHLPDLLRWVKLEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XFB6</accession>
    <name>A0A0P6XFB6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_07795</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062416.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07795"/>
    <dbReference type="EnsemblBacteria" id="KPL78343">
        <property type="protein sequence ID" value="KPL78343"/>
        <property type="gene ID" value="ADN00_07795"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="198" mass="22037" checksum="F506830C57C0583D" modified="2016-01-20" version="1">MASITISRQLGSLGDEIAQIVARRLGWQVIDRELINQAAFESCSPEMALTSVDELGLLGITPSKKECQPYLQAVERILHQRAAQGSFIILGRAGQVVLRGQPDVLHIRIYAPRSVRVERVAVQQRISSEAALAQIKASDRHRRWYLKRYYNAIVDKPRYYDLEINTARLAPESAAALICSAAENILHLSPAPASRHTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XFF7</accession>
    <name>A0A0P6XFF7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_14570</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000035">
        <property type="protein sequence ID" value="KPL73564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063762.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000035.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14570"/>
    <dbReference type="EnsemblBacteria" id="KPL73564">
        <property type="protein sequence ID" value="KPL73564"/>
        <property type="gene ID" value="ADN00_14570"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009247">
        <property type="term" value="P:glycolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd07984">
        <property type="entry name" value="LPLAT_LABLAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004960">
        <property type="entry name" value="LipA_acyltrans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30606">
        <property type="entry name" value="PTHR30606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03279">
        <property type="entry name" value="Lip_A_acyltrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0997">Cell inner membrane</keyword>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022519"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL73564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="310" mass="34584" checksum="FCD09E000E90A27B" modified="2016-01-20" version="1">MDGFVVKGREVRLTTLINSKLGTGLALWLSRSLPGWLGYPVSRLAADLLSGRSRSSQVRALRANLWVVSGEQATREQLDQWVKQSYRNSARAIYDFYHHLRDHQRVLNLVEVDPSFEEVIEKGRSLRAGQVLVVPHVSNFDLVGRAAALRGLQMQVISAPNPPGGYQWQNAIREEVGIEITPASNEALRRALTNLRAGGTVLTGLDRPFDGSKYRLKFFGRPAALPVVHIQLALRTKLPVTVIGGAMKADHTYRVWALPPIAMKEMPDHEAEIVYNAEAVLSAAEEVVRQDPQQWNMTQPVWPEAMQMAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XFZ4</accession>
    <name>A0A0P6XFZ4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peripla_BP_6 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_14355</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the leucine-binding protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000034">
        <property type="protein sequence ID" value="KPL73747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063718.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000034.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14355"/>
    <dbReference type="EnsemblBacteria" id="KPL73747">
        <property type="protein sequence ID" value="KPL73747"/>
        <property type="gene ID" value="ADN00_14355"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1390"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028081">
        <property type="entry name" value="Leu-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000709">
        <property type="entry name" value="Leu_Ile_Val-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13458">
        <property type="entry name" value="Peripla_BP_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00337">
        <property type="entry name" value="LEUILEVALBP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133035" description="Peripla_BP_6 domain-containing protein" evidence="3">
        <location>
            <begin position="23"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="domain" description="Peripla_BP_6" evidence="4">
        <location>
            <begin position="33"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL73747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="385" mass="41165" checksum="CD35EA7AB59FF5ED" modified="2016-01-20" version="1">MKKTKLVSVLFVVMLVSSMLLGACAPKADEDVIKIGYVGALSGETAVWGQAGLNGMLLTAKEINEAGGILGKKVEVVGLDGRGDPTDSVNAFRRLVTEEKVLAVIGTNFSSCNIAMAPIADELKVPLIATAASNPKVTVDENGNLHPYSFRIGFIDPFQGQVLANLASNELGAKTAGVIYDIGSDYSTGLAQYFEEQFVKNGGTVVAKVEAHSGDNDFRSQLSVIAEAKPDVIMVPWIYKDVALIANQARELGITAPMLGGDGWDSPELITMAGPAIEGSFYTSQPSFANPVTKPYYDAYMAEYDNLVPETEALFGHDGLYWIKDALERAGEVSPEALRAALENTTQFDGLMGSMAVDPATHNPAKPASVYTFTNGERVWYGDFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XFZ9</accession>
    <name>A0A0P6XFZ9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATPase AAA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_18035</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL69972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064438.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18035"/>
    <dbReference type="EnsemblBacteria" id="KPL69972">
        <property type="protein sequence ID" value="KPL69972"/>
        <property type="gene ID" value="ADN00_18035"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2908"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011703">
        <property type="entry name" value="ATPase_AAA-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041628">
        <property type="entry name" value="ChlI/MoxR_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07726">
        <property type="entry name" value="AAA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17863">
        <property type="entry name" value="AAA_lid_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_3" evidence="1">
        <location>
            <begin position="36"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="domain" description="AAA_lid_2" evidence="2">
        <location>
            <begin position="228"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL69972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="311" mass="34367" checksum="978AA11605FC1C25" modified="2016-01-20" version="1">MIASAAQKVTRNIQKVIVGKEQSIQLLLTAVLCEGHVLLEDVPGTGKTTLARALAASLGCSFQRIQFTPDLLPSDVTGLSWFNQKTQEFEFRPGPIMSQVVLSDEINRATPRTQSALLEAMQERQVTADGASRPLPRPFLVLATQNPVELEGTFPLPEAQLDRFLIKVNLGYPSLDEENHILERFRAEDPLESLQPVVSAAEILDLIQERKQVRVEDSLRDYIVRVARATRENNDIQLGASPRATLALYQTAQAWAAIQGRDYVLPDDVKLLTPVVLSHRLIISAQAQLRGRTAEQLIDDIVSAVPVPVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XHG2</accession>
    <name>A0A0P6XHG2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphoribosyl pyrophosphate synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_04820</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061897.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04820"/>
    <dbReference type="EnsemblBacteria" id="KPL79248">
        <property type="protein sequence ID" value="KPL79248"/>
        <property type="gene ID" value="ADN00_04820"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.330"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004749">
        <property type="term" value="F:ribose phosphate diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009165">
        <property type="term" value="P:nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029099">
        <property type="entry name" value="Pribosyltran_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005946">
        <property type="entry name" value="Rib-P_diPkinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10210">
        <property type="entry name" value="PTHR10210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14572">
        <property type="entry name" value="Pribosyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13793">
        <property type="entry name" value="Pribosyltran_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01251">
        <property type="entry name" value="ribP_PPkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran_N" evidence="3">
        <location>
            <begin position="7"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00029942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL79248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="320" mass="35264" checksum="93DD6AAD41B2F5BC" modified="2016-01-20" version="1">MLYGDVKLYAGTACPDLSQGIAKYLNQPLCERDVIQFPNENLFVKLHTSVRGQDCYVIQTAAPPIHRNLMELLIMLQTLRLDSAARITAVIPYLWYGRSDKKDQPRIPITARLLADMIEVAGADRYITLDLHAGQIQGFFSIPGDVLTAFHTHVDYLESLLPDMVSPVVVTVDLGFAKKGRNYAARLNLPMAFIEKRRLRNDSNAQALTVIGDVAGRDVILVDDEVDTGGSVAQAVNLLKESGARNVYVVFVHPILSLNAAERLGALPVTQFVTTDTIPLPPEKAKFFGDRLKILSMAPLIGEVILRAHEGRSVGAMFNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XHX7</accession>
    <name>A0A0P6XHX7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ribosome-binding factor A</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">rbfA</name>
        <name evidence="2" type="ORF">ADN00_02695</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Associates with free 30S ribosomal subunits (but not with 30S subunits that are part of 70S ribosomes or polysomes). Required for efficient processing of 16S rRNA. May interact with the 5'-terminal helix region of 16S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer. Binds 30S ribosomal subunits, but not 50S ribosomal subunits or 70S ribosomes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RbfA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000012">
        <property type="protein sequence ID" value="KPL79440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061419.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000012.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02695"/>
    <dbReference type="EnsemblBacteria" id="KPL79440">
        <property type="protein sequence ID" value="KPL79440"/>
        <property type="gene ID" value="ADN00_02695"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030490">
        <property type="term" value="P:maturation of SSU-rRNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00003">
        <property type="entry name" value="RbfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000238">
        <property type="entry name" value="RbfA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023799">
        <property type="entry name" value="RbfA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020053">
        <property type="entry name" value="Ribosome-bd_factorA_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33515">
        <property type="entry name" value="PTHR33515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02033">
        <property type="entry name" value="RBFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89919">
        <property type="entry name" value="SSF89919"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00082">
        <property type="entry name" value="rbfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01319">
        <property type="entry name" value="RBFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0690">Ribosome biogenesis</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="129" mass="15050" checksum="656C96D4A6084082" modified="2016-01-20" version="1">MRIQRIAGRVREEMSELLVYQIQDPRLLGVSVTDVQIDRELAFADIYVSAVEGQERAKDVIEALQHAGSFIRHYLAEKVQLRSFPKLRFFWDPTPERADRMEKLFAQLHQSDGADLEMQDEEGEQEDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XI60</accession>
    <name>A0A0P6XI60_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Septum site-determining protein MinD</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Cell division inhibitor MinD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_02250</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">ATPase required for the correct placement of the division site. Cell division inhibitors MinC and MinD act in concert to form an inhibitor capable of blocking formation of the polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ParA family. MinD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000009">
        <property type="protein sequence ID" value="KPL79803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061336.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000009.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02250"/>
    <dbReference type="EnsemblBacteria" id="KPL79803">
        <property type="protein sequence ID" value="KPL79803"/>
        <property type="gene ID" value="ADN00_02250"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2772"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002586">
        <property type="entry name" value="CobQ/CobB/MinD/ParA_Nub-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010223">
        <property type="entry name" value="MinD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025501">
        <property type="entry name" value="MinD_FleN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01656">
        <property type="entry name" value="CbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003092">
        <property type="entry name" value="MinD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01968">
        <property type="entry name" value="minD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="8" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CbiA" evidence="7">
        <location>
            <begin position="6"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010257"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL79803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="267" mass="29186" checksum="74349878F611823D" modified="2016-01-20" version="1">MTATVITISSGKGGVGKTTTTANLALALAANGKKVVCIDGDIGLRNLDVVMGLENRIVYDLVDVVEGRCRLRQAMIRDKHYEDLFLIPAAQTRDKSSVSPSDMVRLCDELRDEMDFILIDSPAGIERGFRNAVAPADKVLVVTNPEVSAVRDADRIIGLVEAEEKGPARLIINRLNPNMVKRGDMLNAEDIVELLAIEVIGIVPEDENVIVSTNRGQPIVTNPKSKAGQAFRNIALRLLGQQVPFMDLQEKVDFIQRLSMMLRPGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XIM5</accession>
    <name>A0A0P6XIM5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_13375</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063523.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000031.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13375"/>
    <dbReference type="EnsemblBacteria" id="KPL74825">
        <property type="protein sequence ID" value="KPL74825"/>
        <property type="gene ID" value="ADN00_13375"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.26.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023359">
        <property type="entry name" value="Dihydro_DH_chainA_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005720">
        <property type="entry name" value="Dihydroorotate_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01180">
        <property type="entry name" value="DHO_dh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00037">
        <property type="entry name" value="Fer4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="311"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="341"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL74825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="370" mass="39445" checksum="319E3EE3B089E996" modified="2016-01-20" version="1">MAELQTNLWGHVFKNPVIPAAGPNVGSGRMAALAAEGGAGGVLTKTISRVAAEVPHPNMVRIGRDSLLNTELWSELSPEDWFEREYDIALAAARSHNLPLIASIGYSAEDLVDLGPRLEEKGVDLIEFSIHYLDSEQLTRTASALRKAVSIPIIAKLSPHAGDLGEIARLIDPYVDGFACINSFGPTLAIDIENRAPFLGSRFGYGWLSGAALKPLAMRSVFEVARVSQKPIIGVGGVSRGEDVIEFLMAGAAMVGVCTAAILKGPSAYGKIAAEVDAWLEAHGYQSVDEVKGLYLEAMRAGQAVVTTLEETAWVNESRCKACSLCEKVCQFDALKAPLKEIAKVDVSKCAACGLCVSVCPHGALEMRPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XIT3</accession>
    <name>A0A0P6XIT3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glyco_trans_4-like_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01905</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000007">
        <property type="protein sequence ID" value="KPL80049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061272.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000007.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01905"/>
    <dbReference type="EnsemblBacteria" id="KPL80049">
        <property type="protein sequence ID" value="KPL80049"/>
        <property type="gene ID" value="ADN00_01905"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="1">
        <location>
            <begin position="22"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="376" mass="41724" checksum="CB1EA1EA13B64D51" modified="2016-01-20" version="1">MKIACIATSQVPSSTANSIQVMKACQALAQVGNEVCLWVPGARGAEWAALAEQYGLITPFEVRWLPTRQVWRRYDLAWNAARAAKQWGARVVYTWAPQAAVFAQWRGLPAVLELHDRITGKVGPLWFRWFLQSRRPKRLLLITEALRAVLERQFGMALPAPVTQIAPNGTEMERYENLPAAEDARRQLGLPQGLTAVFSGHFYAGRGTDLLFELARHLPELNFVWVGGREKDVAALREKLAEANMENVVLSGFVPNAHLPLYQAAGDFLLMPYERSIAGSGGGDSAAICSPMKMFDYLAAGRVIVTSELPVLHEILNEHNAVFCPPEDAAAWADALRGLMRDPARRESLSARAREDAHSYTWKARAERALDGLRQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XJJ0</accession>
    <name>A0A0P6XJJ0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HDOD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_17190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064283.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17190"/>
    <dbReference type="EnsemblBacteria" id="KPL71425">
        <property type="protein sequence ID" value="KPL71425"/>
        <property type="gene ID" value="ADN00_17190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006675">
        <property type="entry name" value="HDIG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013976">
        <property type="entry name" value="HDOD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08668">
        <property type="entry name" value="HDOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00277">
        <property type="entry name" value="HDIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51833">
        <property type="entry name" value="HDOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HDOD" evidence="1">
        <location>
            <begin position="16"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL71425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="282" mass="31366" checksum="464A5C5AD54764A3" modified="2016-01-20" version="1">MLPRKIDQILSRVDRLWPMPTSVNRTLRAMEDPMITAGYVAELIALDQALAASVLQMANSAAMGFTVNCTSINEAVMRLGFKRLKNLIMSIVAEGPLSRNLSGYRIGAGDLWNHAISTAVTAQWLAQAVGYGDPDEAYLAGLLHDIGKLLLDQYIVLDYSKMIDLMQRYNLRLWQVEEQLLGIDHAAVGGLMAEKWNYPVVLIDAIRCHHAPSLARTRPELPAIVNVANALSAQVGVTNKELFVNEIHPESYNILRLSEDTLEQLRKRVGEYLSASRSQSRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKM7</accession>
    <name>A0A0P6XKM7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">2-nitropropane dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_16025</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16025"/>
    <dbReference type="EnsemblBacteria" id="KPL72111">
        <property type="protein sequence ID" value="KPL72111"/>
        <property type="gene ID" value="ADN00_16025"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3639"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04742">
        <property type="entry name" value="NPD_FabD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014179">
        <property type="entry name" value="PfaD_fam"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02814">
        <property type="entry name" value="pfaD_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="487" mass="53793" checksum="990F3BAF79DC9107" modified="2016-01-20" version="1">MVFVFSDQGRLAMSDQGGGVSGSDYPLLAVLPPIPAQSLGSQRFKETYGTRYALYGGAMANAISSEDMVIEMGRAGMMASFGAGGLLPARIEEAIIKIKSALPNGPYLFNMLNSPFEPLMEQRAVDLYLQHGIRAIEASAYLGMTRGLVRYRASGLSLDQQGGVVIGNRIIAKVSRKEVARHFLSPAPEDMLRKLVEDGEISEQQAQLARRVPVADDITVEADSGGHTDNRPLVALLPVMLAYRASLQEKYHYAEPVRIGAGGGISTPAAALAAFMMGADYLVTGSINQACVESGASDEVRAMLAQAEMTDVIMAPASDMFEMGVKVQVLKRGTLFPMRAGKLYELYSRYNSIEELPASERENLESEIFQRSLEEVWVETVAFFKERDPRQIEKAAQDAHYKMALIFRWYLGLSSRWAARAEASRKMDYQVWCGPSMGAFNDWARGTRFEAIENRKVVDVNRTLLEECAYLSRVQMLRMQGIELPFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKT2</accession>
    <name>A0A0P6XKT2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable molybdenum cofactor guanylyltransferase</fullName>
            <shortName evidence="4">MoCo guanylyltransferase</shortName>
            <ecNumber evidence="4">2.7.7.77</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">GTP:molybdopterin guanylyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Mo-MPT guanylyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Molybdopterin guanylyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Molybdopterin-guanine dinucleotide synthase</fullName>
            <shortName evidence="4">MGD synthase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">mobA</name>
        <name evidence="6" type="ORF">ADN00_15415</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Transfers a GMP moiety from GTP to Mo-molybdopterin (Mo-MPT) cofactor (Moco or molybdenum cofactor) to form Mo-molybdopterin guanine dinucleotide (Mo-MGD) cofactor.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>GTP + H(+) + Mo-molybdopterin = diphosphate + Mo-molybdopterin guanine dinucleotide</text>
            <dbReference type="Rhea" id="RHEA:34243"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
            <dbReference type="ChEBI" id="CHEBI:71310"/>
            <dbReference type="EC" id="2.7.7.77"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="4">The N-terminal domain determines nucleotide recognition and specific binding, while the C-terminal domain determines the specific binding to the target protein.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the MobA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.77" evidence="4"/>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15415"/>
    <dbReference type="EnsemblBacteria" id="KPL72212">
        <property type="protein sequence ID" value="KPL72212"/>
        <property type="gene ID" value="ADN00_15415"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.785"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061603">
        <property type="term" value="F:molybdenum cofactor guanylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02503">
        <property type="entry name" value="MobA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00316">
        <property type="entry name" value="MobA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025877">
        <property type="entry name" value="MobA-like_NTP_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013482">
        <property type="entry name" value="Molybde_CF_guanTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12804">
        <property type="entry name" value="NTP_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 4" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="1 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transf_3" evidence="5">
        <location>
            <begin position="7"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="21"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL72212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="209" mass="22819" checksum="F2538BBA08C35F56" modified="2016-01-20" version="1">MNCLSVAIQAGGGSKRMGVNKALMSFLGEPLITRISRLLSPVSDDLFIITQETEAYQHLGLRTISDEVPNMGAIGGLLTAMAQARCDYVAVVACDMPFVSPGILKHCLEILVDNNADVAIPLTMEGYEPLHAVYRKATCLPAIREAMAAGKKRLISWFSDVKVMGITEDRLSILDPDQLAFINTNTIDDFLQAVEIAKQHPEMLPPNFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XMR1</accession>
    <name>A0A0P6XMR1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidase T</fullName>
            <ecNumber evidence="5">3.4.11.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Aminotripeptidase</fullName>
            <shortName evidence="5">Tripeptidase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Tripeptide aminopeptidase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">pepT</name>
        <name evidence="9" type="ORF">ADN00_11080</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Cleaves the N-terminal amino acid of tripeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>Release of the N-terminal residue from a tripeptide.</text>
            <dbReference type="EC" id="3.4.11.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5 7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="5 7">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the peptidase M20B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.11.4" evidence="5"/>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063077.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11080"/>
    <dbReference type="EnsemblBacteria" id="KPL76508">
        <property type="protein sequence ID" value="KPL76508"/>
        <property type="gene ID" value="ADN00_11080"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.912"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045148">
        <property type="term" value="F:tripeptide aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043171">
        <property type="term" value="P:peptide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00550">
        <property type="entry name" value="Aminopeptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010161">
        <property type="entry name" value="Peptidase_M20B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42994:SF1">
        <property type="entry name" value="PTHR42994:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037215">
        <property type="entry name" value="Peptidase_M20B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01882">
        <property type="entry name" value="peptidase-T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00758">
        <property type="entry name" value="ARGE_DAPE_CPG2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00759">
        <property type="entry name" value="ARGE_DAPE_CPG2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 5" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 5" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="M20_dimer" evidence="8">
        <location>
            <begin position="207"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 6">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5 6">
        <location>
            <position position="175"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="141"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="380"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR037215-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR037215-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL76508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="410" mass="45619" checksum="548A860AFF2DB38F" modified="2016-01-20" version="1">MTNVVEKFLRYVKIDTQSLMDQPTFPSTQKQFDLANLVVAELKQMGLEEVTLDENGYVMATLPATTDRPLPTIGLIAHMDTSQDFSGANVKPQFVEKYDGGDIVLNAAENIVLSPAEFPELLDYVGQELITTDGTTLLGADDKAGVAEILTAVEYLAQHPEMEHGKIRVGITPDEEIGHGADRFDVQKFAADFAYTVDGGEIGALEYENFNAAMARVTIQGRGVHPGSAKNKMINAALVGIELNEMLPVNMRPEYAEGYEGFFHLWRFTADVDHAEMIYLIRDHNRDLYEEKKHLLKSAAQYLNEKYPAGTVDLVIQDQYFNMKEKIAPVMHIIETAKQAMREVGIEPHEVPIRGGTDGARLSFMGLPCPNLFTGGHNFHGRYEFIPTHSMQKAVEVILKIVELYARPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XPM2</accession>
    <name>A0A0P6XPM2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Radical SAM protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_14120</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063672.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000033.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14120"/>
    <dbReference type="EnsemblBacteria" id="KPL74132">
        <property type="protein sequence ID" value="KPL74132"/>
        <property type="gene ID" value="ADN00_14120"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1924"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040086">
        <property type="entry name" value="MJ0683-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43432">
        <property type="entry name" value="PTHR43432"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01084">
        <property type="entry name" value="Uncharacterised_Radical_SAM_Su"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="6">
        <location>
            <begin position="19"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL74132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="290" mass="33435" checksum="24E3BBF8E1BB3F8C" modified="2016-01-20" version="1">MIREMEAKTMLNRYRQPDDWFGLTYGFNIYRGCQHQCIYCDSRSECYQIEDFNDVLVKVNAPEVLRAELKRKRVKGTIGTGSMSDPYTFVERDYRLTRRALEVIAEAGFPLHLLTKSDMVTRDADVLVEIHRKSMAVVAFTLTTADDDLARVLEPYAPPPSRRLRALENLSAAGVRTGVALMPVLPFLEDSEKNLLTIARRAKEVGADYLLPAVGMTLRDRQRLYFYEQLDEHFPGLRARYEQTYGERYDARPLNWKALNAALGAECQRLGLSTRTPRWHPPRVEQLSWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQ06</accession>
    <name>A0A0P6XQ06_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FmdB family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_16960</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064239.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16960"/>
    <dbReference type="EnsemblBacteria" id="KPL71390">
        <property type="protein sequence ID" value="KPL71390"/>
        <property type="gene ID" value="ADN00_16960"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.452"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013429">
        <property type="entry name" value="Regulatory_FmdB_Zinc_ribbon"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029040">
        <property type="entry name" value="RPABC4/Spt4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09723">
        <property type="entry name" value="Zn-ribbon_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00834">
        <property type="entry name" value="CxxC_CXXC_SSSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63393">
        <property type="entry name" value="SSF63393"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02605">
        <property type="entry name" value="CxxC_CxxC_SSSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CxxC_CXXC_SSSS" evidence="2">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL71390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="97" mass="10761" checksum="BAEDEFAE3B5671C9" modified="2016-01-20" version="1">MPVYTYRCEECGFQFERQQKFSEAPLTRCPECGKRSLRKVYTPVGIVFKGSGFYATDHKSPSGNSWGSRSSSDNKSSESKAESTSKDTPKSSADSDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQQ9</accession>
    <name>A0A0P6XQQ9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ATPase AAA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_04575</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061776.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04575"/>
    <dbReference type="EnsemblBacteria" id="KPL79137">
        <property type="protein sequence ID" value="KPL79137"/>
        <property type="gene ID" value="ADN00_04575"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.276"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032423">
        <property type="entry name" value="AAA_assoc_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021886">
        <property type="entry name" value="MgsA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008824">
        <property type="entry name" value="RuvB-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16193">
        <property type="entry name" value="AAA_assoc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12002">
        <property type="entry name" value="MgsA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05496">
        <property type="entry name" value="RuvB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="SSF48019"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="4">
        <location>
            <begin position="53"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="427"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL79137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="468" mass="51788" checksum="45CD497DF9271F3E" modified="2016-01-20" version="1">MSDLFDHAMRQRMRQEAPLAARMRPRTLEEFIGQEHIIGEGKLLRRAIQADRLFSSIIFFGPPGTGKTTLAQLIAAHTHAHFETISAVLAGVPQLREVIAKAEERRKLYQTRTILFVDEVHRWNKAQQDALLPHVESGMIMLIGATTENPYFEVIPALVSRSRIFQLEPLSEEQITRILRQALADEERGYGSRSVQISDEAFQHLVNLSNGDARNALNALELAVESTPADLEGNVQIDLEAAEESIQRRAVIYGKNGDAHYDTISAFIKSVRGSDPDAALYWLAKMLAAGEDPRFILRRLIVLAGEDIGLADPQALVVVTAAAQAFDYIGLPEGYFPIAEATLYLATAPKSNSALAIFEAMKYVEQHGVGPVPTHLMDANRDSKGLGHGKGYKYPHNFPGHFVAQRYLPEDVQAQFYKPSDQGYEAEVSERVSRLRAQQQEGLAGAAGKPSQEKSQLPGHVRPPQKGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XRB8</accession>
    <name>A0A0P6XRB8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Succinate--CoA ligase [ADP-forming] subunit alpha</fullName>
            <ecNumber evidence="2">6.2.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Succinyl-CoA synthetase subunit alpha</fullName>
            <shortName evidence="2">SCS-alpha</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">sucD</name>
        <name evidence="7" type="ORF">ADN00_15295</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 5">Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 5">
            <text>ATP + CoA + succinate = ADP + phosphate + succinyl-CoA</text>
            <dbReference type="Rhea" id="RHEA:17661"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57292"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.2.1.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Carbohydrate metabolism; tricarboxylic acid cycle; succinate from succinyl-CoA (ligase route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 5">Heterotetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the succinate/malate CoA ligase alpha subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.2.1.5" evidence="2"/>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063907.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15295"/>
    <dbReference type="EnsemblBacteria" id="KPL72195">
        <property type="protein sequence ID" value="KPL72195"/>
        <property type="gene ID" value="ADN00_15295"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.761"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00999"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004775">
        <property type="term" value="F:succinate-CoA ligase (ADP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01988">
        <property type="entry name" value="Succ_CoA_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017440">
        <property type="entry name" value="Cit_synth/succinyl-CoA_lig_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033847">
        <property type="entry name" value="Citrt_syn/SCS-alpha_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005810">
        <property type="entry name" value="CoA_lig_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032875">
        <property type="entry name" value="Succ_CoA_lig_flav_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02629">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13607">
        <property type="entry name" value="Succ_CoA_lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001553">
        <property type="entry name" value="SucCS_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00881">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="SSF52210"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01019">
        <property type="entry name" value="sucCoAalpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01216">
        <property type="entry name" value="SUCCINYL_COA_LIG_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00399">
        <property type="entry name" value="SUCCINYL_COA_LIG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0436">Ligase</keyword>
    <keyword evidence="1 2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="CoA_binding" evidence="6">
        <location>
            <begin position="4"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Coenzyme A binding" evidence="2">
        <location>
            <begin position="17"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Coenzyme A binding" evidence="2">
        <location>
            <begin position="98"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="2 3">
        <location>
            <position position="249"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared with subunit beta</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001553-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL72195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="288" mass="30447" checksum="9B388D799EA54DF3" modified="2016-01-20" version="1">MGIFINRQTRVMVQGITGYQGSFHTQKMIEYGTCVVAGVTPGRGGEWVMENKVPVFESVKVAKEATGADASVIFVPARFATDAILEAIDAKVGLIVCITDGIPTQDMMRICSYLKDKDCRLIGPNCPGILTPGEAKLGIIPGDISLAGNVGVVSRSGTLTYEVLYALKRFGVGVSSCVGIGGDLILGTGFVDVLDLFEADPHTDQVVLIGEIGGNEEEAAADFIASRMTKPVIAFIAGKTAPADKRMGHAGAIIEGDRGLAMEKIRSLENAGVKVVDHPEEIPLLLRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XRC2</accession>
    <name>A0A0P6XRC2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_03205</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000014">
        <property type="protein sequence ID" value="KPL79348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79348">
        <property type="protein sequence ID" value="KPL79348"/>
        <property type="gene ID" value="ADN00_03205"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2052"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="235" mass="24926" checksum="17D784FA115C6397" modified="2016-01-20" version="1">MVVFPSAPGNLAELAAAAPQTQFVAASGADLPAGANVSVIRLRPEYTSFTAGYLGVVLAFDFRMGALLPAEGTAAETFVNGGRFFCGLCNSTYSPIVRFPVVSQAPAGTAAGQWQQAVDTLQQNYLYVMYVSPEAASSELLSYLTAMGYTLYGGQTPPDEFRSRWAATVREDLVTPLRALWPGVIAGQGGQTVEASVEIADVNADLLSAGRLEQVQKMIAEMAAGRIYPFNPPME</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XRG0</accession>
    <name>A0A0P6XRG0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_15645</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063966.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72249">
        <property type="protein sequence ID" value="KPL72249"/>
        <property type="gene ID" value="ADN00_15645"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="112"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL72249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="133" mass="14407" checksum="E20F6911A1F9F4BC" modified="2016-01-20" version="1">MEGFLIFIAASLLIEAVVTNIKWVLEGGYNWPRITALVVGIGVAVIFQLDLFAALTMIGIVPFVGFVLTGIILARGANFVNDLITALFSIKTGSKDISSLLEKLQTYQIPEPATARSVPARPDTQTKSTQLRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XRK1</accession>
    <name>A0A0P6XRK1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Response regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_15850</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15850"/>
    <dbReference type="EnsemblBacteria" id="KPL72286">
        <property type="protein sequence ID" value="KPL72286"/>
        <property type="gene ID" value="ADN00_15850"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="20"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL72286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="146" mass="16078" checksum="80B96AB65D627B6D" modified="2016-01-20" version="1">MANSSNTGSLNRKDNSESKTVLVVEDNVSNFVLIARLLGFLGIHCEWKTSGYEVVEFADNLPTLDLVLMDIRLPYEDGYGALKKIKQTPKFAGIPVVAVTAEASEEQIARARAAGFDGFLGKPIDPDRFPDQINRILAGESIWELH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XT54</accession>
    <name>A0A0P6XT54_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_02260</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000009">
        <property type="protein sequence ID" value="KPL79805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061338.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000009.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02260"/>
    <dbReference type="EnsemblBacteria" id="KPL79805">
        <property type="protein sequence ID" value="KPL79805"/>
        <property type="gene ID" value="ADN00_02260"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2774"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001182">
        <property type="entry name" value="FtsW/RodA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30474">
        <property type="entry name" value="PTHR30474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01098">
        <property type="entry name" value="FTSW_RODA_SPOVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0133">Cell shape</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="73"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="102"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="136"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="159"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="181"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="260"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="298"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="336"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL79805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="367" mass="41025" checksum="472DEA168E0398FC" modified="2016-01-20" version="1">MNREYWRNFDFWLLGTVVFLSIFGIVMIRSAIAGNQELAGYDTRQATFVAIGFVIMMGTALMDYHYWQSLTRLMYIFTVFFLLLVFVIGLASFGAARWLDTGLVVVQPAELAKIVMILVLANYFDKTQKQPHDLRWIANSFLLTAGVVVWIFLQPNLSTSIVLFVIWFALLWMSGLPPKYLVLFGILGAILPLVAFPFLEEYQQMRVLNFLFPDPNARHGNTFNVDQALITIGSGGFFGQGYGHSSQVQLRFLKVRHTDFIFSAMAAEFGFVGVLVILALLIFVIIRCLRAARLANDLFGALIAYGFATLIFFQAAVNISVNLNIIPVTGLTLPFISYGGSSLVSLVFGIGLVESVVARRKSFDLKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XT56</accession>
    <name>A0A0P6XT56_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">UDP-N-acetylmuramate--L-alanine ligase</fullName>
            <ecNumber evidence="4 11">6.3.2.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">UDP-N-acetylmuramoyl-L-alanine synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">murC</name>
        <name evidence="15" type="ORF">ADN00_07395</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Cell wall formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + L-alanine + UDP-N-acetyl-alpha-D-muramate = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanine</text>
            <dbReference type="Rhea" id="RHEA:23372"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:70757"/>
            <dbReference type="ChEBI" id="CHEBI:83898"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.8"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the MurCDEF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.8" evidence="4 11"/>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062343.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07395"/>
    <dbReference type="EnsemblBacteria" id="KPL78281">
        <property type="protein sequence ID" value="KPL78281"/>
        <property type="gene ID" value="ADN00_07395"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3301"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008763">
        <property type="term" value="F:UDP-N-acetylmuramate-L-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00046">
        <property type="entry name" value="MurC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000713">
        <property type="entry name" value="Mur_ligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005758">
        <property type="entry name" value="UDP-N-AcMur_Ala_ligase_MurC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01225">
        <property type="entry name" value="Mur_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01082">
        <property type="entry name" value="murC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="6 11" id="KW-0132">Cell division</keyword>
    <keyword evidence="7 11" id="KW-0133">Cell shape</keyword>
    <keyword evidence="10 11" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="5 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0436">Ligase</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 11" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase" evidence="12">
        <location>
            <begin position="3"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_M" evidence="14">
        <location>
            <begin position="106"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="13">
        <location>
            <begin position="313"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="108"/>
            <end position="114"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KPL78281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="461" mass="49502" checksum="4293B5BF6D3BEB62" modified="2016-01-20" version="1">MMHVHLIGIGGTGLSAIARVLLESGYQVSGSDQTLSDLAQDVMRLGARVFVGHHADNILGADLVVRSSAISDANVEVAAARAAGIPVLKRSEFLGRLIADRDSIAIAGTHGKTTTTAMIAYLLTALGEDPSYIIGGVAKDLHSNAHAGQGRAFVIEADEYDRMFLGLHPAVMVVTNLEHDHPDCYPTLAEYQSAFSEFVSQLKPEGILLACADDLAAKTMLFSLPQGCRAFTYGLDPSADYQARQVRVDDAGGIQFDLWLNAPGGERQLVSASLAIPGLHNVRNAAAALAVIHQMGLPLETAAYKLQSFSGTGRRFDILGEALGITLIDDYAHHPTEIKATLAAARARFKNRRIWAVWQPHTFSRTQTLLQDYLTAFGDADQVIITEIYASREAPCDFSSQQVAAKMSQPTARYAATLQAAKELLVSELRPGDVVIVLSAGDAAQMNADLLQDLRRKEGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XTI5</accession>
    <name>A0A0P6XTI5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063058.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76491">
        <property type="protein sequence ID" value="KPL76491"/>
        <property type="gene ID" value="ADN00_10980"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.890"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="135"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="501" mass="54260" checksum="8CDE01DDC44ACC41" modified="2016-01-20" version="1">MKRFLTLQHTGWKFSVQLLTALMLLVVLVIPSIHTVNAGAIPTFDVISIVTDEKVTIKTYNFPANREFTARMGEYGTLGVGGIEVGKVSSGSGGSFEATFNIPSELRGRYRIAIRLESGIYYSYNFFINDKNGTDPYQSSTTKTPTATPSKTATPGPSPTPGSSSGYTGYPTTTVLKVVEDESVTLKTFNFPKNTDFVVRIGEYGTKGVNGTQVASFNSANNVSFEATYNIPAGLKDRDRLSIRIESTSGYYYAYDWFYNKTTSSPYAGSDYGTGGPVSTSTSGTSGIPTTTVLKVVKNDSVTLKTFNFPKNTDFVVRVGEYGTKGVNGVQVATLKTSDSSSFEVTYDIPDSLKDRDRLSIRIESTSGYYYAYDWFYNETTSSPYHGEEYGTGGPVATSTPGSSSSYSGIPTFDIVSVDKNESVKIKTHNFPKDMDFTVRMGAFGTAGVGGTVVTTINSGDGGSFEATYDIPDNLKDSSTIAIRLESSSGYYAYNWFSNSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUB1</accession>
    <name>A0A0P6XUB1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_05665</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061999.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78729">
        <property type="protein sequence ID" value="KPL78729"/>
        <property type="gene ID" value="ADN00_05665"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="192" mass="20771" checksum="9180E3348BF45B57" modified="2016-01-20" version="1">MNNTVKIILFILAGLMVVCLAGMLLAGPVVKSIIQKNAMSIGLSADNAQAIASQMVQFEAPADFGEPYAFEMLGYSLITFTGSDGHSHIYFMQVPEDSGLTEEELLSQAQKMSGSTIGTEFDNAQPMDVVIMGQTVTMLIIDGINSANQPYRQAVGIFTGQDGPILVVFERPLDLWDESELLDFLSSIHQSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XVL5</accession>
    <name>A0A0P6XVL5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_03175</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000014">
        <property type="protein sequence ID" value="KPL79342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061512.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000014.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03175"/>
    <dbReference type="EnsemblBacteria" id="KPL79342">
        <property type="protein sequence ID" value="KPL79342"/>
        <property type="gene ID" value="ADN00_03175"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="156" mass="16642" checksum="78CE283CA1DABD5F" modified="2016-01-20" version="1">MIRLNIPGRDSITLRHLVCDVNGTLAVDGILQPGVAERFARLKNLITIHLLTADTHGRQHQIDEQLGLRAVRISPGNEAGQKAEFVRQLGAPSVAAIGQGANDAAMLKLAALGICVLSTEGLAVETLLSADLLMPDIDSALELFEHPARITASLRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XWP2</accession>
    <name>A0A0P6XWP2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_00165</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060934.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL81003">
        <property type="protein sequence ID" value="KPL81003"/>
        <property type="gene ID" value="ADN00_00165"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL81003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="530" mass="60340" checksum="3A459781A459E853" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XWP5</accession>
    <name>A0A0P6XWP5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_14365</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000034">
        <property type="protein sequence ID" value="KPL73749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063720.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000034.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14365"/>
    <dbReference type="EnsemblBacteria" id="KPL73749">
        <property type="protein sequence ID" value="KPL73749"/>
        <property type="gene ID" value="ADN00_14365"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1392"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015658">
        <property type="term" value="F:branched-chain amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06581">
        <property type="entry name" value="TM_PBP1_LivM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043428">
        <property type="entry name" value="LivM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30482">
        <property type="entry name" value="PTHR30482"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="125"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="175"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="210"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="247"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL73749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="297" mass="31887" checksum="40D3BA172AF637F5" modified="2016-01-20" version="1">MAGYYEGLIILVGINIIAVIGVSILTGFTRLFSFGNGGFMAIGAYTGAILSTKLHTPLVVSILGGMLVAGFIAFLLGKITLGLKGDYFLIATLGFGESVRVIIENLQSVTGGARGYSGIPYKTDLLVILVSVAVAIFIAWNLLHSKMGRNFMAIREQEIAADAIGIDTAKYKNMAFVISAMFAAWAGVLFAHYFTFIVPVMFNMVKSTEMTITVVIGGLGSLTGSIVATTLLTLLPELARAAAEYRMLAYGLAVVLIITLRPSGLMGYKEFSARGIYYWLKDRFTRKAVHSSEEASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XWP6</accession>
    <name>A0A0P6XWP6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PlsC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_08365</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062531.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08365"/>
    <dbReference type="EnsemblBacteria" id="KPL77880">
        <property type="protein sequence ID" value="KPL77880"/>
        <property type="gene ID" value="ADN00_08365"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PlsC" evidence="1">
        <location>
            <begin position="48"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="230" mass="25437" checksum="EBB1F09630E5E534" modified="2016-01-20" version="1">MGDQAAYRVKVVNQIGRWLLRPLGRLLYRILAKPEIDGLENVPKEGSYLIAINHVSIFEPPFVIPFWPVPPEPLGAAEVWREPDKALLAKFYGGIPIDRDAYDRQALDRVVAAIRGGARVLIAPEGRLSRIPGLRRAKLGIAYLAERTNAAIVPVGVSGATQNFLTRALQGQKPVIRMKIGRPFTLPPISALEGSRKEAYQQNADRVMARIAALLPSEYKGYYADFPADD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XXC9</accession>
    <name>A0A0P6XXC9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_01405</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061175.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01405"/>
    <dbReference type="EnsemblBacteria" id="KPL80531">
        <property type="protein sequence ID" value="KPL80531"/>
        <property type="gene ID" value="ADN00_01405"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1034"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030489">
        <property type="entry name" value="TR_Rrf2-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000944">
        <property type="entry name" value="Tscrpt_reg_Rrf2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33221">
        <property type="entry name" value="PTHR33221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02082">
        <property type="entry name" value="Rrf2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00738">
        <property type="entry name" value="rrf2_super"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01332">
        <property type="entry name" value="HTH_RRF2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51197">
        <property type="entry name" value="HTH_RRF2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL80531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="133" mass="14433" checksum="DBE01C0AAE5BE42B" modified="2016-01-20" version="1">MQITRQADYALRAMLYLSELEPNQRAATSQIAENKNIPPSFLAKIISQLSIAGLIHTSRGARGGVSLARPAAEISVLEVVEAIDGPLSLNECTLNKGACPFGSKCPMRPVWCDAQEELVHRLSQTTFAQVINL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XYZ5</accession>
    <name>A0A0P6XYZ5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">G5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_13600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063571.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000032.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13600"/>
    <dbReference type="EnsemblBacteria" id="KPL74334">
        <property type="protein sequence ID" value="KPL74334"/>
        <property type="gene ID" value="ADN00_13600"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007137">
        <property type="entry name" value="DUF348"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011098">
        <property type="entry name" value="G5_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03990">
        <property type="entry name" value="DUF348"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07501">
        <property type="entry name" value="G5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01208">
        <property type="entry name" value="G5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51109">
        <property type="entry name" value="G5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="domain" description="G5" evidence="3">
        <location>
            <begin position="99"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL74334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="540" mass="59361" checksum="E3F129CF85EDA121" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XZZ5</accession>
    <name>A0A0P6XZZ5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pyruvate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061906.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05160"/>
    <dbReference type="EnsemblBacteria" id="KPL78648">
        <property type="protein sequence ID" value="KPL78648"/>
        <property type="gene ID" value="ADN00_05160"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1504"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transket_pyr" evidence="1">
        <location>
            <begin position="6"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="330" mass="35979" checksum="1B29D1031236144F" modified="2016-01-20" version="1">MSGREITYLEAIREALRQEMQRDERVFLMGEDIGVYGGAFGVTLGLLQEFGEDRVIDTPISELGIAGAITGAALTGMRPVGEIMFMDFITLASEQLVNQAAKIRFMFGGKATVPLVMRTPMGSGTGAAEQHSQSLENWFVHVPGIKVVAPATPAEAKGLLIESIRDDNPVLFLEAKLLYKTKGEVPEEPYTIPLGKADIKRAGRDLTIITYSIMVKRSLEAAEQLAQEGIDVEVIDLRTLKPLDKDAIIASVKKTGKVLIVHEAVKTGGFGGELAGVISESEAFDYLDAPIVRLAGRDMPVPYNRTLEYHTVPQVENIVEAARKLARREV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y052</accession>
    <name>A0A0P6Y052_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_13445</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13445"/>
    <dbReference type="EnsemblBacteria" id="KPL74837">
        <property type="protein sequence ID" value="KPL74837"/>
        <property type="gene ID" value="ADN00_13445"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="322"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="357"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="492"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="548"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL74837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="634" mass="71597" checksum="3E53440DE3548BEC" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y2E8</accession>
    <name>A0A0P6Y2E8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_04380</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061736.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04380"/>
    <dbReference type="EnsemblBacteria" id="KPL79105">
        <property type="protein sequence ID" value="KPL79105"/>
        <property type="gene ID" value="ADN00_04380"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03225">
        <property type="entry name" value="ABC_cobalt_CbiO_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015856">
        <property type="entry name" value="ABC_transpr_CbiO/EcfA_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="8"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="41"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL79105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="280" mass="31080" checksum="543B55EB998F4802" modified="2016-01-20" version="1">MTEPTPYIQVKDLVFRYADGTQALNNINLTIGEGEFIAFIGQNGSGKTTLSKCLNGLFKPTSGDILVDGLNSRTTPIAQMVRRVGYVFQNPDHQLFNSNCWDEIAYGPRNIELSEEEVKARVEEAARVVGLPEENYTEHPFFLTKGMRQRVAIASILALRPKVIIVDEPTTGQDSRQSIEIMDFLLSLNQERGHTIIVISHVMPIVARYARRVVAMGMGKILLDGPTDEVFAQTEILAKTYIEPPQITQLAQSVSDLGFYPGTLTVESMVEQYKTIAAKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y2S1</accession>
    <name>A0A0P6Y2S1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alanine racemase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_05070</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061868.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05070"/>
    <dbReference type="EnsemblBacteria" id="KPL79215">
        <property type="protein sequence ID" value="KPL79215"/>
        <property type="gene ID" value="ADN00_05070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="7"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL79215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="336" mass="37052" checksum="1262EB909BD8F961" modified="2016-01-20" version="1">MEQKKVRTIADIAQIAGVSKSTVSRALSDSPLISEETRARIQAIASQHQFQINLPASRLSKQRSSTLAFVMQCECAKFSVEDLFSLEILGAITNAAAEQGYDLLMVNIAPDAQDWVQDYYFTGRVDGFILMTSVHKTSHVRSLIKHQAPFIAWGNPLPLEMFNYIKGDNIRGGRLATQHLIERGRHNIAFIGGPADDIEVNQRFQGYCQALEQAGLPFEPQRVAYGDFSSQSGAAAMQALLERQPNLDGVFVNSDIMAIAAIRILQQHGRRVPRDVAVVGYDDVSMAAFATPPLTTIRQNIPEIGKKLVQSLIAYLDDGITHQLTMPVELIVRSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y2X2</accession>
    <name>A0A0P6Y2X2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminotransferase</fullName>
            <ecNumber evidence="1">2.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_11575</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.-" evidence="1"/>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL75998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063176.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11575"/>
    <dbReference type="EnsemblBacteria" id="KPL75998">
        <property type="protein sequence ID" value="KPL75998"/>
        <property type="gene ID" value="ADN00_11575"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3790"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="2">
        <location>
            <begin position="48"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL75998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="370" mass="41537" checksum="544868723801B96D" modified="2016-01-20" version="1">MQPFKLERYFAQHEFSAEVLMSSSDCESLSLETLLNLCDPETEHLWKNLSLGYTESQGLPLLRAEISTLYTRVHPDQVITLAPEEGIYIAMRTLLRPGDHVICLAPAYQSLYQVAADSGCQVSLCWLRQTTSGWQLDPQQIKDLIRPNTRMLVVNFPHNPSGFLPSRALFEKIIDLAAQHNLILFSDEMYRLLEYKTEDRLPAACDAYPNAVSLGGLSKSMSLPGLRAGWLAARNREWIQSFQRYKDYTTICSSAPSEVLAVIALRAREEIVQTNLGIIRANTALAQAFFAHNATWLEWIPPLAGPIALPHYTGPGSVDEFCLSVLQQQNVMIVPGSMFEMEGNYFRVGLGRKNLPEALRRLQTYLDAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y318</accession>
    <name>A0A0P6Y318_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA-(apurinic or apyrimidinic site) lyase</fullName>
            <ecNumber evidence="3">4.2.99.18</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">ADN00_11735</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FPG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.99.18" evidence="3"/>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063206.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11735"/>
    <dbReference type="EnsemblBacteria" id="KPL76025">
        <property type="protein sequence ID" value="KPL76025"/>
        <property type="gene ID" value="ADN00_11735"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140078">
        <property type="term" value="F:class I DNA-(apurinic or apyrimidinic site) endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019104">
        <property type="term" value="F:DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015886">
        <property type="entry name" value="DNA_glyclase/AP_lyase_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012319">
        <property type="entry name" value="FPG_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035937">
        <property type="entry name" value="MutM-like_N-ter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_S13-like_H2TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000214">
        <property type="entry name" value="Znf_DNA_glyclase/AP_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010663">
        <property type="entry name" value="Znf_FPG/IleRS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01149">
        <property type="entry name" value="Fapy_DNA_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06831">
        <property type="entry name" value="H2TH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06827">
        <property type="entry name" value="zf-FPG_IleRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00898">
        <property type="entry name" value="Fapy_DNA_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01232">
        <property type="entry name" value="H2TH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="SSF46946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81624">
        <property type="entry name" value="SSF81624"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51068">
        <property type="entry name" value="FPG_CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51066">
        <property type="entry name" value="ZF_FPG_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="13" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="11" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="6 14" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="FPG_CAT" evidence="16">
        <location>
            <begin position="2"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="FPG-type" evidence="15">
        <location>
            <begin position="219"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KPL76025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="271" mass="30174" checksum="7311CA12C44B6E99" modified="2016-01-20" version="1">MPELPEIANRTREIQENLIGKQIASITIIQPKCLNCPPEEFQASLNGAVIQSARYKGKWIFVETTQGWLLLNMGMGGEMILTDPQHLPEKNRLIFHFADQTCLSVNFWWFGYAHYVPTGQLDQHEMSAKLGPNVLDLSPEEFSTLLSSKKGQLKSFLLNQSNLAGIGNAYIHDILFFAGLHPLRPIPTLSSDEIARLYAAIRKGLTMSLEKGGAWYELNLYGQKGGFTLEDLVIAYKDNQPCPSCGTPIQKLKTGSTSSFLCPACQPLDNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y6D2</accession>
    <name>A0A0P6Y6D2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_00075</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the YggT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL80989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060919.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00075"/>
    <dbReference type="EnsemblBacteria" id="KPL80989">
        <property type="protein sequence ID" value="KPL80989"/>
        <property type="gene ID" value="ADN00_00075"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003425">
        <property type="entry name" value="CCB3/YggT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02325">
        <property type="entry name" value="YGGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL80989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="87" mass="9878" checksum="DD586A2ABEC10113" modified="2016-01-20" version="1">MVEILIVLVRVIAQILILLILAEVILSYILSPYHPVRATISKIVDPILDPIRRLVPPVKMIDFSPLILLIIIQVLEYLLVAILQTFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y995</accession>
    <name>A0A0P6Y995_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">K(+)-insensitive pyrophosphate-energized proton pump</fullName>
            <ecNumber evidence="9">7.1.3.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Membrane-bound proton-translocating pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Pyrophosphate-energized inorganic pyrophosphatase</fullName>
            <shortName evidence="9">H(+)-PPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">hppA</name>
        <name evidence="10" type="ORF">ADN00_07660</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Proton pump that utilizes the energy of pyrophosphate hydrolysis as the driving force for proton movement across the membrane. Generates a proton motive force.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>diphosphate + H(+)(in) + H2O = 2 H(+)(out) + 2 phosphate</text>
            <dbReference type="Rhea" id="RHEA:13973"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="EC" id="7.1.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the H(+)-translocating pyrophosphatase (TC 3.A.10) family. K(+)-insensitive subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.3.1" evidence="9"/>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062390.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07660"/>
    <dbReference type="EnsemblBacteria" id="KPL78320">
        <property type="protein sequence ID" value="KPL78320"/>
        <property type="gene ID" value="ADN00_07660"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3362"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009678">
        <property type="term" value="F:pyrophosphate hydrolysis-driven proton transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01129">
        <property type="entry name" value="PPase_energized_pump"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004131">
        <property type="entry name" value="PPase-energised_H-pump"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31998">
        <property type="entry name" value="PTHR31998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03030">
        <property type="entry name" value="H_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001265">
        <property type="entry name" value="H+-PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01104">
        <property type="entry name" value="V_PPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-1278">Translocase</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="138"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="170"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="264"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="300"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="327"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="370"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="408"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="472"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="510"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="576"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="601"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="668"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="site" description="Determinant of potassium independence" evidence="9">
        <location>
            <position position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01129"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL78320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="689" mass="70998" checksum="3A005BE64EBFBBE3" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YA70</accession>
    <name>A0A0P6YA70_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Sugar ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_05625</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061993.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05625"/>
    <dbReference type="EnsemblBacteria" id="KPL78723">
        <property type="protein sequence ID" value="KPL78723"/>
        <property type="gene ID" value="ADN00_05625"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1602"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="21"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="273"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="53"/>
            <end position="60"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL78723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="528" mass="57803" checksum="17EEF1BE5A3A6A37" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YAU5</accession>
    <name>A0A0P6YAU5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">LuxR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_03795</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061634.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03795"/>
    <dbReference type="EnsemblBacteria" id="KPL79024">
        <property type="protein sequence ID" value="KPL79024"/>
        <property type="gene ID" value="ADN00_03795"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="9"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="146"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL79024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="214" mass="23556" checksum="9DAA6C3A356C7EC8" modified="2016-01-20" version="1">MKSETNAIKVLIVDDHAVVRKGLRSFLQAYDDLELVGEASDGDEAVQFCEKLQPDVILMDLMMPRMDGETATAIIRQRFPQVQIIALTSFKGDRLVQKLLNAGAIGYLLKNVSADELAQSIRAARSGQPTLSPEATKALINSATQPRLPDLNLTAREMEVLKLMANGFSNPQIAEKLSISRSTVKFHVSSILAKMNLNTRTEVVSFALHNHLVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YAX8</accession>
    <name>A0A0P6YAX8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_04115</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79070">
        <property type="protein sequence ID" value="KPL79070"/>
        <property type="gene ID" value="ADN00_04115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045443">
        <property type="entry name" value="DUF6504"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20114">
        <property type="entry name" value="DUF6504"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="126" mass="14606" checksum="44E4F323D743A3D7" modified="2016-01-20" version="1">MPVETQPLHFIGEEIEVTFKRPPALEKSPECPDAFTWRGEAYEVRRVLSEKQDFSRRGRMARNMAPAHAQRASLHGSWGVGRFFFRVEVEGGRCFELYYDRAPEDSGDRKGNWFLRSELQAVGEQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YBN0</accession>
    <name>A0A0P6YBN0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_03135</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000014">
        <property type="protein sequence ID" value="KPL79335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061504.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000014.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03135"/>
    <dbReference type="EnsemblBacteria" id="KPL79335">
        <property type="protein sequence ID" value="KPL79335"/>
        <property type="gene ID" value="ADN00_03135"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006230">
        <property type="entry name" value="MutL"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13941">
        <property type="entry name" value="MutL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="574" mass="61801" checksum="4FB92B22D321C651" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YCD5</accession>
    <name>A0A0P6YCD5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ENDO3c domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_02380</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000010">
        <property type="protein sequence ID" value="KPL79664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061359.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000010.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02380"/>
    <dbReference type="EnsemblBacteria" id="KPL79664">
        <property type="protein sequence ID" value="KPL79664"/>
        <property type="gene ID" value="ADN00_02380"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2693"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00056">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1670.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011257">
        <property type="entry name" value="DNA_glycosylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003651">
        <property type="entry name" value="Endonuclease3_FeS-loop_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003265">
        <property type="entry name" value="HhH-GPD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023170">
        <property type="entry name" value="HhH_base_excis_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10576">
        <property type="entry name" value="EndIII_4Fe-2S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00730">
        <property type="entry name" value="HhH-GPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00478">
        <property type="entry name" value="ENDO3c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00525">
        <property type="entry name" value="FES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48150">
        <property type="entry name" value="SSF48150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ENDO3c" evidence="5">
        <location>
            <begin position="46"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL79664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="229" mass="25467" checksum="AA11A76B63FE3A35" modified="2016-01-20" version="1">MSDSQPADPQTEHHARLIYERLLQYYGLPEWRDPLPAMDELVSTILSQNTNDTNRDLAFNRLRAAFSTWEAVRDAPAEAVMDAIRPAGLANQKGPRIQQVLRQITNERGSLDLDFLKGWDAEEARAWLLQFNGVGPKTAAIVLQFALGIPAFPVDTHVHRVSGRLGLRPAEMNAEQAHPHLAALFDPQTYGPAHLNLIRLGREICHARKPNCRACPLNDLCPSAQVGSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YDN3</accession>
    <name>A0A0P6YDN3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MazG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000006">
        <property type="protein sequence ID" value="KPL80121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061251.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000006.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80121">
        <property type="protein sequence ID" value="KPL80121"/>
        <property type="gene ID" value="ADN00_01800"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004518">
        <property type="entry name" value="MazG_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03819">
        <property type="entry name" value="MazG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MazG" evidence="1">
        <location>
            <begin position="30"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="102" mass="11612" checksum="8D1831211CB2BE77" modified="2016-01-20" version="1">MQTNHTITEIVRQYYQFRGLTEPDANQAFLFLVSEVGELSDAFVENQGQWIRNNPDRERDVQAEIGDVLMMLTVFAASQGFDPLEAMLAKMARKGFAPVEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YFR3</accession>
    <name>A0A0P6YFR3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_00395</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060975.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL81036">
        <property type="protein sequence ID" value="KPL81036"/>
        <property type="gene ID" value="ADN00_00395"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3472"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003609">
        <property type="entry name" value="Pan_app"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00024">
        <property type="entry name" value="PAN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycos_transf_1" evidence="2">
        <location>
            <begin position="220"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="Apple" evidence="1">
        <location>
            <begin position="368"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL81036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="433" mass="50057" checksum="7E0393ED3F337346" modified="2016-01-20" version="1">MNTNNGNTKKLNIGFISTRFAGTDGVSLETAKWAEVLEAMGHTCYYFAGICDRPASHSMVVPKAFYHHPEIEEHHQRFWGETRRSELDTQWIHQMRESFKKEIYHFKNEFQIDLLIPENVLSIPLNIPLGLAIAEFIAETNIPTIAHHHDFTWERKRFIVNSVWDYITMAFPPTIWSIQHVVINSSARHQLARRTGVGSTIIPNVMDYERKPPAVDAYSEDLRQALGLDPDELFILQPTRVVQRKGIEHSIELVSRLNRKARLVISHASGDEGQEYEQRVRHYADMMGVKALFISDLFDEKRRIKPNGEKIYSLWDAYPQADLITYPSLIEGFGNAFLEAIYFKRPIVVNNYTIFAIDIRTKGFNVIEFDNYITQDTVQKTVEVLDNPQRCMQMCEENYRLACQHYSYSVLRTRLSNLISHFFGFGGGNGNQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GLD4</accession>
    <name>A0A0N8GLD4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">T2SSF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_15250</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063898.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15250"/>
    <dbReference type="EnsemblBacteria" id="KPL72186">
        <property type="protein sequence ID" value="KPL72186"/>
        <property type="gene ID" value="ADN00_15250"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.752"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.81.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018076">
        <property type="entry name" value="T2SS_GspF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042094">
        <property type="entry name" value="T2SS_GspF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00482">
        <property type="entry name" value="T2SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="90"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="113"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="256"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="295"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="7">
        <location>
            <begin position="150"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL72186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="320" mass="35591" checksum="55755CD8BE4AA6F0" modified="2016-01-20" version="1">MPFNPILILGVGGALAFIMLIIGIVISITSERSLVEERLGQYVDQQEEIAKDAATPLTDWLNRRVEGSSFAERVSKSLARADIKMKPGEYIAMMIIVAFGVGIILWFIGGRSIFAGVIGAIIGLFLPGMYVKRQQSKRLIRFNEQLADMLNLMVNGLRAGYSTAQAMEAISRELPPPISDEFRRVVQEMQLGVPTERALDNLLRRIPSDDLDLVITAINVQREVGGNLAEILDTISHTIRERVRIKGEIRVLTSQVMYSGRFLSILPLLVMGVLYLLNREYMMEFFKPENVPCGYIALGVAAALIIAGYFIMTKLGQIEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GLE0</accession>
    <name>A0A0N8GLE0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_15555</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063948.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15555"/>
    <dbReference type="EnsemblBacteria" id="KPL72234">
        <property type="protein sequence ID" value="KPL72234"/>
        <property type="gene ID" value="ADN00_15555"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005654">
        <property type="entry name" value="ATPase_AFG1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03969">
        <property type="entry name" value="AFG1_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL72234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="258" mass="29009" checksum="BE6C3BCDDA9EDAE7" modified="2016-01-20" version="1">MDTMSNLTRKIADSVSRVNTSTPPSPPKPYTGICKPDCEICGGIGYVRQDLPVSDPGFGKAQLCPNVDLFTHYKGRSGLESDERDLSWSNIADFNGVGKAVEAVQTVVERGYGWIFLWGDFGLAKSLILKTAVSSYIRERKEPASYVRMAELLDHLRSAYDSSNPSEDSQARLDFWSTIPLLCIDEFDRVRDTAYASERRFVLMDRRYEKACGRKNITIMASNSDPALIDGYLRDRIFDGRFKVIKLVGKSARPMMSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GN67</accession>
    <name>A0A0N8GN67_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ABC transmembrane type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_08885</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062644.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08885"/>
    <dbReference type="EnsemblBacteria" id="KPL77250">
        <property type="protein sequence ID" value="KPL77250"/>
        <property type="gene ID" value="ADN00_08885"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="86"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="129"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="176"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="15"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL77250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="210" mass="22737" checksum="EB09A6D82F61F8C7" modified="2016-01-20" version="1">MSYLINHFEVVAPLFLQHVQLTLTVLFFSLLIGVPLGLLLARVAWLRGPVMSVLGVIYTIPSLSLFVLLIPLFGLGTRPAVVALTAYAQLLLVRNWLVGLTTIDPAIIEAARGMGMNGWQRFWQVELPLAMPMLLAGIRLVSLSSIGIGMIAAFINAGGLGLLLFQGVTTANYEKIFAGGLAASVLSFSANFLLRYLERRAENVIRGKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNE3</accession>
    <name>A0A0N8GNE3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_08235</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062571.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08235"/>
    <dbReference type="EnsemblBacteria" id="KPL77858">
        <property type="protein sequence ID" value="KPL77858"/>
        <property type="gene ID" value="ADN00_08235"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.649"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008323">
        <property type="entry name" value="UCP033563"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36454">
        <property type="entry name" value="PTHR36454"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06245">
        <property type="entry name" value="DUF1015"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL77858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="439" mass="48924" checksum="9ED73F2783FD3307" modified="2016-01-20" version="1">MKIISSLGFQIPQVLLPGPEINPQQWAVIACDQFTSQPEYWQAVEEKVAESPSTLRLILPEVYLESPKKDTLTSSVQANMADYLERGILHPVDGIILVERQIQGKTRRGIMLALDLERYDYSKGSQSLIRATEGTIIERLPPRMKIREGAPLELPHILVLIDDPQKTVIEPLAARTGQLKKIYDFDLMFDSGHLTGYLVDDESLQNQVVDAIADLANPAAFQAKYNLDQPQEVLLFAMGDGNHSLATAKAIWENMKAQVGMDHPARYALVEVENVHDESLVFEPIHRVLFDVKQDFKTAFAAKFGSRITFRVCADLEEMVRAVENQPSGAQIIGVVNSREFGVIQIDQPELNLAVGTLQNFLDGWLKTGAASSIDYVHGADVVARLGAQPGNLGFFLPAMDKSDLFKTVILDGALPRKTFSMGEAKEKRFYMECRKIVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNF0</accession>
    <name>A0A0N8GNF0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosome maturation factor RimM</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rimM</name>
        <name evidence="5" type="ORF">ADN00_08260</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">An accessory protein needed during the final step in the assembly of 30S ribosomal subunit, possibly for assembly of the head region. Probably interacts with S19. Essential for efficient processing of 16S rRNA. May be needed both before and after RbfA during the maturation of 16S rRNA. It has affinity for free ribosomal 30S subunits but not for 70S ribosomes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Binds ribosomal protein S19.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="2">The PRC barrel domain binds ribosomal protein S19.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RimM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08260"/>
    <dbReference type="EnsemblBacteria" id="KPL77914">
        <property type="protein sequence ID" value="KPL77914"/>
        <property type="gene ID" value="ADN00_08260"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.654"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00014">
        <property type="entry name" value="Ribosome_mat_RimM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011961">
        <property type="entry name" value="16S_RimM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027275">
        <property type="entry name" value="PRC-brl_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011033">
        <property type="entry name" value="PRC_barrel-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002676">
        <property type="entry name" value="RimM_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036976">
        <property type="entry name" value="RimM_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05239">
        <property type="entry name" value="PRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01782">
        <property type="entry name" value="RimM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50346">
        <property type="entry name" value="SSF50346"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02273">
        <property type="entry name" value="16S_RimM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1 2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="RimM" evidence="3">
        <location>
            <begin position="17"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="PRC" evidence="4">
        <location>
            <begin position="104"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF05239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL77914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="176" mass="19519" checksum="DEC22660B11FD6C6" modified="2016-01-20" version="1">MDGSSGSPNSGEPVFLVIGRLRRPHGVAGEINMEVLTDFPERIRKGAVLLVGESHRELVLESARPHGKGILIRFAGINDPETVGLLRNELVYKAAANLPKLPADEYYHHDLLGMQVFLENGQKLGVLREIIETGANDVYQVETEDGKEVLLPAIESVIMEINTDEGRMIVRLQEWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNL2</accession>
    <name>A0A0N8GNL2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 9">Argininosuccinate synthase</fullName>
            <ecNumber evidence="2 9">6.3.4.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">Citrulline--aspartate ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">argG</name>
        <name evidence="10" type="ORF">ADN00_06700</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + L-aspartate + L-citrulline = 2-(N(omega)-L-arginino)succinate + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10932"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57472"/>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.4.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 2/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the argininosuccinate synthase family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.5" evidence="2 9"/>
    <dbReference type="EMBL" id="LGCL01000018">
        <property type="protein sequence ID" value="KPL78410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062208.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000018.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06700"/>
    <dbReference type="EnsemblBacteria" id="KPL78410">
        <property type="protein sequence ID" value="KPL78410"/>
        <property type="gene ID" value="ADN00_06700"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2251"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00113"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004055">
        <property type="term" value="F:argininosuccinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01999">
        <property type="entry name" value="Argininosuccinate_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00005">
        <property type="entry name" value="Arg_succ_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001518">
        <property type="entry name" value="Arginosuc_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018223">
        <property type="entry name" value="Arginosuc_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023434">
        <property type="entry name" value="Arginosuc_synth_type_1_subfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024074">
        <property type="entry name" value="AS_cat/multimer_dom_body"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11587">
        <property type="entry name" value="PTHR11587"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00764">
        <property type="entry name" value="Arginosuc_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69864">
        <property type="entry name" value="SSF69864"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00032">
        <property type="entry name" value="argG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00564">
        <property type="entry name" value="ARGININOSUCCIN_SYN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00565">
        <property type="entry name" value="ARGININOSUCCIN_SYN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3 9" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="12"/>
            <end position="20"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>L-citrulline</name>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>L-citrulline</name>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>L-citrulline</name>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="266"/>
        </location>
        <ligand>
            <name>L-citrulline</name>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="278"/>
        </location>
        <ligand>
            <name>L-citrulline</name>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL78410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="420" mass="46231" checksum="6A3ED4C9021937B1" modified="2016-01-20" version="1">MPKKAVHKVVLAYSGGLDTSNIVPWLIENYGCEVICFTADIGQGGEFNQMEEKALASGASQFVLRDLKAEFAESYLYPLIHSGAVYEGKYLLGTALARPLIAAHQVAVAQELGADALAHGGTGKGNDQVRFELTYMALDPTLTVISPWREWDIRTRADALAYARAHNIPVPATAGEKRVYSRDRNLWHYAHEGGPLEEAWDAPDEEMYLLSASPENALDKAAYVTLDFNNGNPTAVDGEALSPLEMIQRLNSLGAMHGIGRADLVESRLVGLKSHGVYETPAGTILTAAHRELESLVLDKDTLHFKAGAALKYAELIYNGLWFSPLRESLDAFFDSTQTPVSGTIRLKLYKGNIIPVGRKSPNSLYRDEYATFGLDDVYDQQESQGFTNVFGLHLKVRALNRLTPGGKIPKPDFTRFKRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNN4</accession>
    <name>A0A0N8GNN4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_06605</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000017">
        <property type="protein sequence ID" value="KPL78586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062188.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000017.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78586">
        <property type="protein sequence ID" value="KPL78586"/>
        <property type="gene ID" value="ADN00_06605"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="47"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="170" mass="19106" checksum="B09EC5A8C12CE4B0" modified="2016-01-20" version="1">MMMDSGSILFLVGLSLLVILTISAPLYNHALKRIRLSSPQEDRRGQLAFTRLCLQAAENELEELNIDRSASRVAEQDFQARALKLAEEMEILKAEEQQLELVLRYQAEASRTGAQPEDDLAQEQELEALIKAYRRGRSEKAAGLCPNCGQAYLRGDRFCARCGEQLDYGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNP3</accession>
    <name>A0A0N8GNP3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_05210</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061916.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05210"/>
    <dbReference type="EnsemblBacteria" id="KPL78658">
        <property type="protein sequence ID" value="KPL78658"/>
        <property type="gene ID" value="ADN00_05210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901135">
        <property type="term" value="P:carbohydrate derivative metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05008">
        <property type="entry name" value="SIS_GlmS_GlmD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05009">
        <property type="entry name" value="SIS_GlmS_GlmD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035466">
        <property type="entry name" value="GlmS/AgaS_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035490">
        <property type="entry name" value="GlmS/FrlB_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="SIS" evidence="2">
        <location>
            <begin position="49"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="2">
        <location>
            <begin position="223"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="389" mass="42932" checksum="7A35305DA2C0D670" modified="2016-01-20" version="1">MNKEMIDVLKQEEKHRKQHPYWVWESIQSIPEMLAQCWNEDVRQDIESVIQECKNREIERLVFLGRGSSYFAALSAKPFIQKITHLPVACYVSNVFEAYPYDKCDEKTAVFFNSHSGKSEGDLRIVELVKSLGAYTVGVTDIADSSLAEAVDQLLIGPGGSKVELPATRTYATAIYRTLLFALAFGKALGVAQDVDEYETALKDLPEKMRKFVPAFEEQAPEIVSILKDCKSLIVVGSGPNFGNAEEAGMAFNQSSGIPTISYEMENYIHGPIQALNDQTGVILIATPSPLQGRMFSLASAAKTIGAKVVLITSVDSRDIPETDGLVSLPAGIPDLFSPVASMIPLWQIGYHFGLLGNGSHPDRLSMDKEEFKAAFTHLMKSDKWVSMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNQ0</accession>
    <name>A0A0N8GNQ0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Phosphoglycerate mutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_05575</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061984.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05575"/>
    <dbReference type="EnsemblBacteria" id="KPL78714">
        <property type="protein sequence ID" value="KPL78714"/>
        <property type="gene ID" value="ADN00_05575"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1592"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="229" mass="25578" checksum="0B6CA00386575106" modified="2016-01-20" version="1">MSDQPATRVYLVRHGATQLSAEDRFAGAVDVKLSEEGKFQAARLAERLADDAISAVYCSPMARTVATASIVAKPHNLPLIQRDGLREINHGHWEGMRRADVEAQFSEEYAAWEEDPFTFAPQGGEAGVNVIARALPILREIVINHRGQNVLVVSHKATIRLLISSVLGFDARGYRDRLDQSPACLNVLDFRDPVRARLMLFNDVSHYTDQPERSGGRLSKWWDETLDQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNQ3</accession>
    <name>A0A0N8GNQ3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Haloacid dehalogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_05720</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062008.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05720"/>
    <dbReference type="EnsemblBacteria" id="KPL78738">
        <property type="protein sequence ID" value="KPL78738"/>
        <property type="gene ID" value="ADN00_05720"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1620"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="279" mass="31406" checksum="137B2DBD9B3F3639" modified="2016-01-20" version="1">MTPTYPVLPGSQIEIIQPAIQRGNIRHALFDFDGTISLIREGWQAVMQPMMVEILMQTPRHEERDQIEALVKEFVTRLTGKQTVYQMIQLAEEIEKRGGQAKDPLVYKHQYHALLMEHIQHRLEQLKAGQANPVDMVVPGSFEILKSLRERGVACYLASGTDEVFVLEEAELLGVTPYFKGVYGAQDDYKNFSKKMVIDRIIQENHLGGSELVAFGDGYVEIEDTKSVGGISVGVASNEATRAGIDEWKRSRLIAAGADVIVPDFGEHEQLVRYLFMEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WN05</accession>
    <name>A0A0P6WN05_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">zf-HC2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_16870</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064222.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16870"/>
    <dbReference type="EnsemblBacteria" id="KPL71377">
        <property type="protein sequence ID" value="KPL71377"/>
        <property type="gene ID" value="ADN00_16870"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041916">
        <property type="entry name" value="Anti_sigma_zinc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027383">
        <property type="entry name" value="Znf_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13490">
        <property type="entry name" value="zf-HC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="zf-HC2" evidence="2">
        <location>
            <begin position="10"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL71377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="385" mass="42431" checksum="5FD8E9B9F2A75F02" modified="2016-01-20" version="1">MHVNDDTLRALLDGELDLSQAEEIHAHIQSCAECSRHMAVIQQRMQTVRAAFSTMESAATQKPLSPTAALSLFASRKKEKFPMSIFNIKRPVWAALVAVLALVIAFTFPPVQALARDFLALFRVEKVETMTLDTLNVEELSRNQNLFNALSQLFAESTTVTYGNPDEYVEVSGEAQAEEILDFDVRMPGATFPPDQMRANTGFAAEIIIDRERAQQVMDQISANEVMLPENIDGAEIEVSSVGVLRMKYGTCPEEDAEQTDWQKECMIFSQAPSPVVSTPPDLNLQELIKTGLLTLGVSPEEAAAFSQSSDWTTTLTIPLPKGKMQHREVEVDGVTGSMFEHPSYGDPDEPRGYTLVWVKNGIVYTIAGANTETKAIELANSLAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WN30</accession>
    <name>A0A0P6WN30_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">Flagellar hook-associated protein 1</fullName>
            <shortName evidence="7">HAP1</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">flgK</name>
        <name evidence="10" type="ORF">ADN00_17125</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Bacterial flagellum</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2 7">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the flagella basal body rod proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064270.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17125"/>
    <dbReference type="EnsemblBacteria" id="KPL71414">
        <property type="protein sequence ID" value="KPL71414"/>
        <property type="gene ID" value="ADN00_17125"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.487"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009424">
        <property type="term" value="C:bacterial-type flagellum hook"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001444">
        <property type="entry name" value="Flag_bb_rod_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010930">
        <property type="entry name" value="Flg_bb/hook_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002371">
        <property type="entry name" value="FlgK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30033">
        <property type="entry name" value="PTHR30033"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00460">
        <property type="entry name" value="Flg_bb_rod"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06429">
        <property type="entry name" value="Flg_bbr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01005">
        <property type="entry name" value="FLGHOOKAP1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02492">
        <property type="entry name" value="flgK_ends"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Flg_bb_rod" evidence="8">
        <location>
            <begin position="8"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="domain" description="Flg_bbr_C" evidence="9">
        <location>
            <begin position="406"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF06429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL71414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="466" mass="51549" checksum="009B8D42E6D53483" modified="2016-01-20" version="1">MPNLFSGINMAFRAMMSHQQAIETIQHNVANVNTPGYHRQEVMLQASAPSSSSLGLERGLGAAQNGTGVEVDRIRRVTMEFFDIRYRAETSHQKRWELESEILQQVEFVMAETSTDGLLTKLNNFWAGWQALSADPSNLSLRTNLRDIAVTLTDAFNTRSVRLDSLQKDQDLTIRQRVDEINSLTAQLATLNGEITRVRSMGDQPNDYMDQRDVLLDRLAEIAGATAHYQDDGSVMVNVSGHSIVTGNTYNAIEYYPNAEGLMEIRWTADGTEFVPSDGELTGLFEARDVFIPQQKAGLDALATKLMERINEVHQQGYGSNGSHLVDFFEGTDAATFKISDEIRADLANIAASSVSGAAGDGENARLLFNVYQEEVMSGTTFNAYYNNQVTNFGIEVQRAKTNATDRKIVADAISNQRESVSGVSLDEEAANLVKSQRAYQAATRMMNVFDELLDIIINQMGQAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WPW1</accession>
    <name>A0A0P6WPW1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Galactose-1-phosphate uridylyltransferase</fullName>
            <ecNumber evidence="15">2.7.7.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">ADN00_15955</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 14 15">
            <text>alpha-D-galactose 1-phosphate + UDP-alpha-D-glucose = alpha-D-glucose 1-phosphate + UDP-alpha-D-galactose</text>
            <dbReference type="Rhea" id="RHEA:13989"/>
            <dbReference type="ChEBI" id="CHEBI:58336"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:66914"/>
            <dbReference type="EC" id="2.7.7.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="13">
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </cofactor>
        <text evidence="13">Binds 1 Fe cation per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="12">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 15">Carbohydrate metabolism; galactose metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">Belongs to the galactose-1-phosphate uridylyltransferase type 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.12" evidence="15"/>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064177.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15955"/>
    <dbReference type="EnsemblBacteria" id="KPL72109">
        <property type="protein sequence ID" value="KPL72109"/>
        <property type="gene ID" value="ADN00_15955"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3624"/>
    <dbReference type="UniPathway" id="UPA00214"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008108">
        <property type="term" value="F:UDP-glucose:hexose-1-phosphate uridylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033499">
        <property type="term" value="P:galactose catabolic process via UDP-galactose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00608">
        <property type="entry name" value="GalT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001937">
        <property type="entry name" value="GalP_UDPtransf1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019779">
        <property type="entry name" value="GalP_UDPtransf1_His-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005850">
        <property type="entry name" value="GalP_Utransf_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005849">
        <property type="entry name" value="GalP_Utransf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11943">
        <property type="entry name" value="PTHR11943"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02744">
        <property type="entry name" value="GalP_UDP_tr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01087">
        <property type="entry name" value="GalP_UDP_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000808">
        <property type="entry name" value="GalT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="SSF54197"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00209">
        <property type="entry name" value="galT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00117">
        <property type="entry name" value="GAL_P_UDP_TRANSF_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 15" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="8 15" id="KW-0299">Galactose metabolism</keyword>
    <keyword evidence="13" id="KW-0408">Iron</keyword>
    <keyword evidence="6 12 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 15 18" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 15 18" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 12" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="GalP_UDP_transf" evidence="16">
        <location>
            <begin position="5"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="GalP_UDP_tr_C" evidence="17">
        <location>
            <begin position="184"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-alpha-D-glucose binding; shared with dimeric partner" evidence="11">
        <location>
            <begin position="29"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-alpha-D-glucose binding" evidence="11">
        <location>
            <begin position="78"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-alpha-D-glucose binding" evidence="11">
        <location>
            <begin position="160"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-alpha-D-glucose binding; shared with dimeric partner" evidence="11">
        <location>
            <begin position="312"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-alpha-D-glucose binding; shared with dimeric partner" evidence="11">
        <location>
            <begin position="317"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-UMP-histidine intermediate" evidence="10 14">
        <location>
            <position position="167"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>UDP-alpha-D-glucose</name>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>UDP-alpha-D-glucose</name>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12 14">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>UDP-alpha-D-glucose</name>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="282"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="297"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="299"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="324"/>
        </location>
        <ligand>
            <name>UDP-alpha-D-glucose</name>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010951"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000808-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000808-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000808-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR000808-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU000506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF02744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KPL72109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="353" mass="40711" checksum="3B27518C76DE3F0E" modified="2016-01-20" version="1">MPEPFNPSEHPHRRFNPLTGNYVLVSPHRMKRPWLGQVESPARVQLPEHDPACYLCPGNARANGESMPEYTSTHVFTNDFSALLPGPVSLADSDSELMVTQPVKGTCRVICFSPRHDLTLPEMGLQEIGNVIQTWAEQYTDLGKEYAWVQVFENKGAIMGCSNPHPHGQVWAQDTLPTEVAKEDQNQVDYFRRRQSVMLMDYLRMEEESGERLVASNRSWVGLVPFWAVWPFELLLLPRRHVLRFTDLTPTEKEDLADILKRLLTRYDNLFQTSFPYSMGWHGAPFLPGDFTHWQLHAHFYPPLLRSAAVKKFMVGYEMMAEPQRDLTAEQAAEWLRRVSEVHYKQVNATPQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WT45</accession>
    <name>A0A0P6WT45_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH luxR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_15760</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063989.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72270">
        <property type="protein sequence ID" value="KPL72270"/>
        <property type="gene ID" value="ADN00_15760"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="18"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL72270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="166" mass="18551" checksum="2E4B5C311671B98F" modified="2016-01-20" version="1">MGKPVEKKTAKLRAEERRKVVAANILAGLSYRQIADALNISIGTISNDVKKITERLEKEQVEDLSQALRLEIARLDQLLNTLWSKATNGDLSCIDRILKISDQRAKLLGLYDANFNINVTKGVDLQKARQERWKNIAGIINAVLDDEEEELEDFADGASDTTDPTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WTE0</accession>
    <name>A0A0P6WTE0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Helicase ATP-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_18750</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064567.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18750"/>
    <dbReference type="REBASE" id="132900">
        <property type="entry name" value="OapP3M1ORF18760P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70084">
        <property type="protein sequence ID" value="KPL70084"/>
        <property type="gene ID" value="ADN00_18750"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3058"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015668">
        <property type="term" value="F:type III site-specific deoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045572">
        <property type="entry name" value="RE_endonuc_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19778">
        <property type="entry name" value="RE_endonuc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="1">
        <location>
            <begin position="87"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="926" mass="106169" checksum="A2832BD84E66D767" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WVR7</accession>
    <name>A0A0P6WVR7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_14895</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FGGY kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000036">
        <property type="protein sequence ID" value="KPL73075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063826.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000036.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14895"/>
    <dbReference type="EnsemblBacteria" id="KPL73075">
        <property type="protein sequence ID" value="KPL73075"/>
        <property type="gene ID" value="ADN00_14895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000577">
        <property type="entry name" value="Carb_kinase_FGGY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="Carb_kinase_FGGY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018483">
        <property type="entry name" value="Carb_kinase_FGGY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018484">
        <property type="entry name" value="Carb_kinase_FGGY_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02782">
        <property type="entry name" value="FGGY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00370">
        <property type="entry name" value="FGGY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000538">
        <property type="entry name" value="GlpK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00445">
        <property type="entry name" value="FGGY_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FGGY_N" evidence="2">
        <location>
            <begin position="4"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="FGGY_C" evidence="3">
        <location>
            <begin position="254"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL73075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="502" mass="55083" checksum="080616D27173B52D" modified="2016-01-20" version="1">MTHLLGLDIGTTGCKATLFDLQGKLVSAASHEYSVQFPKPGWAEQDAELVWDLAQQVMREVTYKSGQRNVAAIGLSVQGEAITPVDAKGNALRPMILGMDTRTVEQNQWLEEKFGKKRLFEKTGMPIHTINTLPKLLWLREFEPQLWKEAERFMLYEDFLIRKMTGESVVSRCLASRTQLYSHQEDGWSVEVLEALDLDQKRLSVIADSGFAVGRLHRKISDAIGFAEPPMVVTGGHDQSCGAFGVGLTQPGLASVSTGTAEVVEVALASPNVSQPLFEGNISVYAHVYKKLFVTMTLNHSGGLLFRWFRDTFGQEEIREAQTSGEDAYQLLLANAPEGPTNLLVLPHFSGSGTPTFDTASKGAILGMGFTTSKAEMAKAILEGLTYELRLNLDVMRSGGVQIDELRAIGGGAKSDLWLQLKADITGTRVVVPQVTEAASMGAAFLAGQGAGLFADAGEAVNQYLRFGKVFEPDNRRVKQYEEKFALYSEVYPTLKSLHHRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WXB0</accession>
    <name>A0A0P6WXB0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_17930</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000043">
        <property type="protein sequence ID" value="KPL70910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064413.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000043.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70910">
        <property type="protein sequence ID" value="KPL70910"/>
        <property type="gene ID" value="ADN00_17930"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025699">
        <property type="entry name" value="ABC2_memb-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13346">
        <property type="entry name" value="ABC2_membrane_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="261"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="344"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="368"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="409"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="437"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="464"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="494"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="520" mass="57347" checksum="0219AF7FF44E6F19" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WXN3</accession>
    <name>A0A0P6WXN3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_17585</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000042">
        <property type="protein sequence ID" value="KPL71212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL71212">
        <property type="protein sequence ID" value="KPL71212"/>
        <property type="gene ID" value="ADN00_17585"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="209"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="235"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="261"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL71212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="289" mass="30866" checksum="F50259BCDC2896BE" modified="2016-01-20" version="1">MMDTVNDHHEQTLPIKSRVSARLLIGAGMVMAGLVFLAEQSLRTGWLFTAFFPLLGVLLLLPGLVLHNFGLVIAGAIVTGVGSGVFVILNPALDLALYQRLGLMFAAFGAGFGLVWLISLIWQLKRPAWWALVPAGVLAGVGGAFWFTSLRFIDFVLYVLVGLGLALLAWGVFERLLGLIIPGCLLLGVGIGNYLAWGAGVEQNALSQTGIMLVCFALGFVLVIVFSRVVTPHFVWWPIIPGALMAVVGWGLYLGGNPGGAASFIGNTGSVALILLGLYLLLLRREIRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WXY4</accession>
    <name>A0A0P6WXY4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">2-oxoacid:ferredoxin oxidoreductase subunit gamma</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_16860</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064221.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16860"/>
    <dbReference type="EnsemblBacteria" id="KPL71376">
        <property type="protein sequence ID" value="KPL71376"/>
        <property type="gene ID" value="ADN00_16860"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.432"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016903">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.920.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019752">
        <property type="entry name" value="Pyrv/ketoisovalerate_OxRed_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002869">
        <property type="entry name" value="Pyrv_flavodox_OxRed_cen"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01558">
        <property type="entry name" value="POR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53323">
        <property type="entry name" value="SSF53323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="POR" evidence="2">
        <location>
            <begin position="11"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL71376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="179" mass="19282" checksum="F15DA0908FA669FB" modified="2016-01-20" version="1">MQTEIIISGFGGQGALFAGQLMAYSAMDNQLEVTWFPSYGPEMRGGTASCTVIISDEEIGAPVVGMPTAVIAMNLPSLDKYEPQVKPGGLLVVNASMVNRQALRTDIRSAHIPANEIAERIGDRRLTNMVLLGSLLANLNVLDLKTVEASLRVHTPERHQRLVPLNIQALEEGATYLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WY20</accession>
    <name>A0A0P6WY20_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">MotA_ExbB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ADN00_17230</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MotA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064291.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17230"/>
    <dbReference type="EnsemblBacteria" id="KPL71431">
        <property type="protein sequence ID" value="KPL71431"/>
        <property type="gene ID" value="ADN00_17230"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.508"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000540">
        <property type="entry name" value="Flag_MotA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002898">
        <property type="entry name" value="MotA_ExbB_proton_chnl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01618">
        <property type="entry name" value="MotA_ExbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01307">
        <property type="entry name" value="MOTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="36"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="146"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="179"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="MotA_ExbB" evidence="9">
        <location>
            <begin position="101"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL71431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="262" mass="27932" checksum="2D69F3498F03D76F" modified="2016-01-20" version="1">MDLSTIVGLILALVILVIVLIMDGGSPAELFAHPSAIILIVGGSLMATTVASPLEVMLRIPKMLMISAKDEKFDIQGAIERIASMADKARRDGLLALEEESKKIDDAFLKRGIMMVVDGVDPSQVKAILMANITQMKNRHKAGYEMFAAAGAFAPTFGIIGTVMGLISVLKQLDDPNKLATSIAGAFLATLWGLLMANLIYLPMGGKLKAKSTAEVNYRVMLMEGILAIQAGENPRIIREKLGSYLPPAVLAKAESAAPEKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZW1</accession>
    <name>A0A0P6WZW1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_13970</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063645.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000033.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74108">
        <property type="protein sequence ID" value="KPL74108"/>
        <property type="gene ID" value="ADN00_13970"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL74108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="98" mass="10875" checksum="AA40157EAD309D12" modified="2016-01-20" version="1">MKVNPLKLHRDLGDAGLPVTSVDETGRVIYLRALSADEARKAEEIIAAHDPSPDERQRTLEQDRQAGICDRDLLDALWNWVVGGSRESVDDILARRAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X178</accession>
    <name>A0A0P6X178_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_12245</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063302.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76104">
        <property type="protein sequence ID" value="KPL76104"/>
        <property type="gene ID" value="ADN00_12245"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3925"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="179"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL76104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="396" mass="43753" checksum="F8FE8FA7F5C9B1ED" modified="2016-01-20" version="1">MNSDHKQTLIQYQRILEISRRLTSEQSLDALLYTIVQAAAEISASEAASILLYDEPNQRLHFQAATNMGPDTMRGISVPTESLAGWVAINRAPVIVPDVRQDKRWFGDLQQKKSGFATRSLIAVPMIARERLVGVLEVLNKMENTYNQDDLELLQILSGQAALAIEQTRLYQQSDMIAELVHELRTPLTSIGTIAYLLQRPTVGEAERLSLAKTIQQETQRLSNLSSSFLDLARLEAGRVGLCLTEFNLSQMIEECIEIIRPSAAEQNIEVIFQAQTPELTVRADPNQIKQVLLNLLTNAVKYNRPQGKITIAQQMENKGVSVSVSDTGIGIPPEQSAHIFEKFYRVSGEETASRAGTGLGLSICKRIIENHGGKISFTSALNQGSTFTIHLPASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X184</accession>
    <name>A0A0P6X184_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fucose isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_14870</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000036">
        <property type="protein sequence ID" value="KPL73073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063821.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000036.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14870"/>
    <dbReference type="EnsemblBacteria" id="KPL73073">
        <property type="protein sequence ID" value="KPL73073"/>
        <property type="gene ID" value="ADN00_14870"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1837"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008736">
        <property type="term" value="F:L-fucose isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006004">
        <property type="term" value="P:fucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015888">
        <property type="entry name" value="Fuc_isomerase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009015">
        <property type="entry name" value="Fucose_isomerase_N/cen_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02952">
        <property type="entry name" value="Fucose_iso_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53743">
        <property type="entry name" value="SSF53743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fucose_iso_C" evidence="2">
        <location>
            <begin position="339"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL73073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="470" mass="51699" checksum="5F32FDA47C3740CE" modified="2016-01-20" version="1">MAKATLGLIVGNRDFFPSRFVTEGRNDLLQLFKEMDIEAIVIDEKETNLGGVETRSEAKICGELFKKNIDKIEGVLVILPNFGNELGIAETLRISGLNVPVLVQAYPDDVQKMSLEGRRDSFCGKFSACNVLRQYGYAYSLTANHTVHPKSESFRKDLEKFVAVCKVVKGLKKARLGAIGARPDAFKTVRFSEKLFERSGISVTTVDLSEIIGNASRLKDTDSQVVSKLDEIKSYVPTQKVPAASLLKMAKLGLVIENWMNDNEIDATAIQCWESIQKNYGVNVCGLMSMMGEKLLPSACEVDVAGVLGMYALTLASGKPSALVDWNNNYGDDPNKCVLFHCGNFPKSFYDDKVEMYLADVLGTTLGNENVYGALAGRIPSGPLTYARVSTDDVNGKIRTYFGEGRFTDDELPTFGGRGVIEIPNMQTLLQNLCKGGFEHHVGISRSHVAGVLEEAFGTYLGWEVYYHKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X1B8</accession>
    <name>A0A0P6X1B8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">(P)ppGpp synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_14785</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">In eubacteria ppGpp (guanosine 3'-diphosphate 5'-diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the relA/spoT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000036">
        <property type="protein sequence ID" value="KPL73059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063806.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000036.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14785"/>
    <dbReference type="EnsemblBacteria" id="KPL73059">
        <property type="protein sequence ID" value="KPL73059"/>
        <property type="gene ID" value="ADN00_14785"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1820"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015969">
        <property type="term" value="P:guanosine tetraphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05399">
        <property type="entry name" value="NT_Rel-Spo_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01668">
        <property type="entry name" value="TGS_RSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004811">
        <property type="entry name" value="RelA/Spo_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045600">
        <property type="entry name" value="RelA/SpoT_AH_RIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007685">
        <property type="entry name" value="RelA_SpoT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033655">
        <property type="entry name" value="TGS_RelA/SpoT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13291">
        <property type="entry name" value="ACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19296">
        <property type="entry name" value="DUF5913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04607">
        <property type="entry name" value="RelA_SpoT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02824">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00954">
        <property type="entry name" value="RelA_SpoT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="SSF81271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00691">
        <property type="entry name" value="spoT_relA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD" evidence="4">
        <location>
            <begin position="44"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="TGS" evidence="5">
        <location>
            <begin position="417"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="3">
        <location>
            <begin position="668"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="113"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL73059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="742" mass="84527" checksum="D6A210AF843FE110" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X415</accession>
    <name>A0A0P6X415_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 2">50S ribosomal protein L24</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rplX</name>
        <name evidence="4" type="ORF">ADN00_12545</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">One of the proteins that surrounds the polypeptide exit tunnel on the outside of the subunit.</text>
    </comment>
    <comment type="function">
        <text evidence="2">One of two assembly initiator proteins, it binds directly to the 5'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal ribosomal protein uL24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063359.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12545"/>
    <dbReference type="EnsemblBacteria" id="KPL76156">
        <property type="protein sequence ID" value="KPL76156"/>
        <property type="gene ID" value="ADN00_12545"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3990"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06089">
        <property type="entry name" value="KOW_RPL26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01326_B">
        <property type="entry name" value="Ribosomal_L24_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041988">
        <property type="entry name" value="KOW_RPL26/RPL24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003256">
        <property type="entry name" value="Ribosomal_L24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12903">
        <property type="entry name" value="PTHR12903"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17136">
        <property type="entry name" value="ribosomal_L24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01079">
        <property type="entry name" value="rplX_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="KOW" evidence="3">
        <location>
            <begin position="4"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL76156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="110" mass="12244" checksum="A3670D3FD07FEBA8" modified="2016-01-20" version="1">MKVKIRKGDLVKVISGRGEDKGKTGEVIKVLPDESRVVVQGVNMRTKHQRQVQSQGRTINPGRVRFEAPLHISNVMVVCPKCGKATRVGLLRENDAVRRVCKKCNALIDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X4H7</accession>
    <name>A0A0P6X4H7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Phosphate acyltransferase</fullName>
            <ecNumber evidence="3 4">2.3.1.274</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Acyl-ACP phosphotransacylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Acyl-[acyl-carrier-protein]--phosphate acyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Phosphate-acyl-ACP acyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">plsX</name>
        <name evidence="5" type="ORF">ADN00_13575</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the reversible formation of acyl-phosphate (acyl-PO(4)) from acyl-[acyl-carrier-protein] (acyl-ACP). This enzyme utilizes acyl-ACP as fatty acyl donor, but not acyl-CoA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>a fatty acyl-[ACP] + phosphate = an acyl phosphate + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:42292"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:14125"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:59918"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:138651"/>
            <dbReference type="EC" id="2.3.1.274"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Lipid metabolism; phospholipid metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer. Probably interacts with PlsY.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="4">Associated with the membrane possibly through PlsY.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the PlsX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.274" evidence="3 4"/>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063566.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000032.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13575"/>
    <dbReference type="EnsemblBacteria" id="KPL74329">
        <property type="protein sequence ID" value="KPL74329"/>
        <property type="gene ID" value="ADN00_13575"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1291"/>
    <dbReference type="UniPathway" id="UPA00085"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043811">
        <property type="term" value="F:phosphate:acyl-[acyl carrier protein] acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00019">
        <property type="entry name" value="PlsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003664">
        <property type="entry name" value="FA_synthesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012281">
        <property type="entry name" value="Phospholipid_synth_PlsX-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30100">
        <property type="entry name" value="PTHR30100"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02504">
        <property type="entry name" value="FA_synthesis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002465">
        <property type="entry name" value="Phsphlp_syn_PlsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00182">
        <property type="entry name" value="plsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="4" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00024069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL74329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="337" mass="35968" checksum="D772DDF55D2AC480" modified="2016-01-20" version="1">MAIVLDGMGSDQYPEPEVTGALTAAEELQEEIILVGQQELLEPRLKAANTKGLPVRIVHAPDVLEMGEKAVESARKKPNNSMAIGLDLVKSGEARAFVTAGNTGAAMFNGLRKLGRIKGVQRPALTAMFPVMTGYTVVLDIGANADCRPNFLQQFAVMGSIYAQKALGVENPRIGLLSNGEEAGKGNQLIKDTYHLMEEIGLNFIGNVEAKELFAGHADVVVTDGFTGNVLLKTSESVAKMLLTVLKEELMASTRTKMGAFLAKPAFGKVKKMLDPSEVGAAPLLGIDGLVFVGHGRSDAHAIHSALRAAHVAANNNLLEALRENIQSRFETTPENE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X4Q7</accession>
    <name>A0A0P6X4Q7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_07840</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000020">
        <property type="protein sequence ID" value="KPL78079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062435.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000020.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78079">
        <property type="protein sequence ID" value="KPL78079"/>
        <property type="gene ID" value="ADN00_07840"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="121" mass="13302" checksum="8C3E4F3FD3CB4F5C" modified="2016-01-20" version="1">MNKMKLGNFIAQTLTEIIDGVSIAQDYAKEKGACINPKYVKWSEIRGHYVDRVASGKDESPLLSPIEFEILLTVGEDDKAQGGLGIFASSLGIGIKGETNDYSETINRIKFQILAILPQQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5L4</accession>
    <name>A0A0P6X5L4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_07810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062418.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78344">
        <property type="protein sequence ID" value="KPL78344"/>
        <property type="gene ID" value="ADN00_07810"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3396"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="176" mass="19111" checksum="8A8A4802B67471C2" modified="2016-01-20" version="1">MHLNIAQSEMQAVFKSGAVGQLVSGLIWLLSAAFSTWVSRQSGVLILFFGGMVIFPLTQLALKLTGHSRQITPGNPLSALARQIAFFVPLCLPLVIAAYTANPNWYYPAFLIIVGAHYLPFVFLYGTRLYTFLAASMVMGGVLIGWLLPNLFVPGGWLGAGLLLAFAALLWRIPAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5T4</accession>
    <name>A0A0P6X5T4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_08980</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062660.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77262">
        <property type="protein sequence ID" value="KPL77262"/>
        <property type="gene ID" value="ADN00_08980"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL77262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="88" mass="9732" checksum="E4A0610A453D2340" modified="2016-01-20" version="1">MTNYLPHKLDDFAELLIQIAVFQMNTLFSLVIGEKACIEIGAERLSRKEQACPHDQLSLVDAGAMQRRNAPNIANLTKCSSGSWDPSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5V7</accession>
    <name>A0A0P6X5V7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_12895</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063429.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000027.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL75533">
        <property type="protein sequence ID" value="KPL75533"/>
        <property type="gene ID" value="ADN00_12895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL75533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="188" mass="21617" checksum="37C4A73C353D4811" modified="2016-01-20" version="1">MKHSVHIGVYFFLLLEDYIDAQTEFVHRLDLSLERFARNLGHSGAVVKPFVGDIEATKAEVLRKSWTERELHEIRKTPGLLLINVDFVVFDPREHPWIYINLGERVQQEEPSVPRIWIDHILNKLAESANNTEKDIFQEANKILNEVPLSDVAAIFEVKPGVFGFSIDLLKGGKLLTTLFERMSSKHQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X673</accession>
    <name>A0A0P6X673_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">VTC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13360"/>
    <dbReference type="EnsemblBacteria" id="KPL74860">
        <property type="protein sequence ID" value="KPL74860"/>
        <property type="gene ID" value="ADN00_13360"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1156"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.100.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018966">
        <property type="entry name" value="VTC_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042267">
        <property type="entry name" value="VTC_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09359">
        <property type="entry name" value="VTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VTC" evidence="1">
        <location>
            <begin position="32"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="257" mass="29874" checksum="D63396B3323C6A40" modified="2016-01-20" version="1">MQTYTSTQWLNQVLNAYSPITLKEMDSVALLNRIDTKFVFSMGRLYSLLAALRPLYRVLSVQGQRLNHYRTLYFDTPAFDLYRLHVNGRADRFKVRSREYVDSQLSFLEVKHKTRKDRTIKDRISTPAPLDDLTPESEQWLDSVLPFDSRSLQPKVWNTFTRVTLVSNTGCERVTLDTNLVFSNAFNEIRLDGIVIAEVKLDSRSTRSPFLTRMQDERIHPQGFSKYVIGASLLYDHLKKNALKSKLILLNRMTQGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X6S3</accession>
    <name>A0A0P6X6S3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_11690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063197.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11690"/>
    <dbReference type="EnsemblBacteria" id="KPL76017">
        <property type="protein sequence ID" value="KPL76017"/>
        <property type="gene ID" value="ADN00_11690"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3813"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="4"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="227" mass="25894" checksum="34BAEAAA1D4E2853" modified="2016-01-20" version="1">MQVSVIIPVYNEVKTICAVLERIKQVGIVDEIIIVDDGSSDGTREMLASLESDPLIHIVFHPHNQGKGSAVRTGIQSATKDIIIIQDADLEYEPGDYPSLIQPILDGQAKVVYGSRFLGAQKRDFLLLSKLANLFLTFVTNLLYQQSLTDMETCYKVFRRDVVKDITFHSRRFEFEPEFTAKILKRHIHIHEVPVHYNSRGFDEGKKIGVKDGLESLWTLVKYRFVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X6X1</accession>
    <name>A0A0P6X6X1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Endonuclease MutS2</fullName>
            <ecNumber evidence="7">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">mutS2</name>
        <name evidence="11" type="ORF">ADN00_08600</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Endonuclease that is involved in the suppression of homologous recombination and may therefore have a key role in the control of bacterial genetic diversity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the DNA mismatch repair MutS family. MutS2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="7"/>
    <dbReference type="EMBL" id="LGCL01000022">
        <property type="protein sequence ID" value="KPL77683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08600"/>
    <dbReference type="EnsemblBacteria" id="KPL77683">
        <property type="protein sequence ID" value="KPL77683"/>
        <property type="gene ID" value="ADN00_08600"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1433"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045910">
        <property type="term" value="P:negative regulation of DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03280">
        <property type="entry name" value="ABC_MutS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00092">
        <property type="entry name" value="MutS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005747">
        <property type="entry name" value="MutS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS_family"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002625">
        <property type="entry name" value="Smr_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036063">
        <property type="entry name" value="Smr_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="PTHR11361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361:SF14">
        <property type="entry name" value="PTHR11361:SF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01713">
        <property type="entry name" value="Smr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005814">
        <property type="entry name" value="MutS_YshD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00463">
        <property type="entry name" value="SMR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160443">
        <property type="entry name" value="SSF160443"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="SSF48334"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01069">
        <property type="entry name" value="mutS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00486">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50828">
        <property type="entry name" value="SMR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 7" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="2 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Smr" evidence="10">
        <location>
            <begin position="719"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="684"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="524"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="340"/>
            <end position="347"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL77683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="796" mass="88622" checksum="38F990017AB5C616" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X6X8</accession>
    <name>A0A0P6X6X8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_08795</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000022">
        <property type="protein sequence ID" value="KPL77692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08795"/>
    <dbReference type="EnsemblBacteria" id="KPL77692">
        <property type="protein sequence ID" value="KPL77692"/>
        <property type="gene ID" value="ADN00_08795"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL77692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="247" mass="27414" checksum="BD69CE5F92F8680D" modified="2016-01-20" version="1">MLEVRDLSVVFPDDTGGLEALEQMSLSVQPREFVCLLGPSGCGKSTLLRVLAGLVPPTQGSVTYQTCAHCNREPRIALVFQNANLMPWRNVLQNITLPLEMQGVEEPKAEKMARELISLVGLEGFEKNWPGDLSGGMAQRVAIARALIQDPDLLLLDEPFGALDALTRERMGTELLHIWQRSRKTVLMVTHSISEALLLSDRVLVFTPRPGRICLDLPVDLPRPRAEEVRYSPRFGELARALRQAIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X765</accession>
    <name>A0A0P6X765_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Enolase</fullName>
            <ecNumber evidence="8">4.2.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">2-phospho-D-glycerate hydro-lyase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">2-phosphoglycerate dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">eno</name>
        <name evidence="13" type="ORF">ADN00_18075</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:10164"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="4.2.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="8">The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Secreted</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Cell surface</location>
        </subcellularLocation>
        <text evidence="8">Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the enolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.11" evidence="8"/>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL69980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064446.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18075"/>
    <dbReference type="EnsemblBacteria" id="KPL69980">
        <property type="protein sequence ID" value="KPL69980"/>
        <property type="gene ID" value="ADN00_18075"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2916"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00187"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000015">
        <property type="term" value="C:phosphopyruvate hydratase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004634">
        <property type="term" value="F:phosphopyruvate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03313">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00318">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000941">
        <property type="entry name" value="Enolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020810">
        <property type="entry name" value="Enolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020809">
        <property type="entry name" value="Enolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020811">
        <property type="entry name" value="Enolase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11902">
        <property type="entry name" value="PTHR11902"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00113">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03952">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001400">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00148">
        <property type="entry name" value="ENOLASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00002">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01192">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01193">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="SSF51604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="SSF54826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01060">
        <property type="entry name" value="eno"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00164">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Enolase_N" evidence="12">
        <location>
            <begin position="5"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="Enolase_C" evidence="11">
        <location>
            <begin position="140"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8 10">
        <location>
            <begin position="366"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8 9">
        <location>
            <position position="207"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8 9">
        <location>
            <position position="339"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="287"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="314"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent; in inhibited form" evidence="8">
        <location>
            <position position="339"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="390"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KPL69980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="427" mass="46026" checksum="9EBF39A5B8CE24E1" modified="2016-01-20" version="1">MESTIEYVHAREILDSRGNPTVEVEVSLESGAFGRAAVPSGASTGIHEALELRDEDKSRYNGKGVLKAVEHVNTEIADTILGMDALDQSAVDKAMLDKDGTPNKSKFGANAILGVSLAVARAAADEVALPLYRYLGGVTAKLLPVPMFNILNGGVHANWQGTDLQEFMIAPVGAPNFREAVRWGSEVYHALKGVLKSSGYTTGVGDEGGFAPALKTNAEAVEVILKAIEKAGYKPGEQIALALDPASSGFYEDGLYNLRTEGKKVTSAEMVAMYADWVKKYPIVVLEDGLAEDDWEGWKLLNQTIGDKIELVGDDLFVTNVERVSRGIRENVANAVLIKLNQIGSISETIATIEMARKAGWGSMVSHRSGETIDSFIADFTVAMSTGHLKTGAPCRGERVEKYNQLMRIEEELGEAAVYAGRKAFVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7E5</accession>
    <name>A0A0P6X7E5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_18730</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064564.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18730"/>
    <dbReference type="EnsemblBacteria" id="KPL70080">
        <property type="protein sequence ID" value="KPL70080"/>
        <property type="gene ID" value="ADN00_18730"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3055"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110001">
        <property type="term" value="C:toxin-antitoxin complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008201">
        <property type="entry name" value="HepT-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01934">
        <property type="entry name" value="DUF86"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-1277">Toxin-antitoxin system</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL70080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="118" mass="13932" checksum="14433CE458E2E079" modified="2016-01-20" version="1">MFIEDRPRNWKIRIQDILKCIARIQEYTSGLSLDDFQKDTLRIDAVIRNLEIIGEAASHIPIEIQQKYPDLAWFEMRGMRNIMAHEYFGVSISIIWQTIKRDLAPLAEGMNEILRQEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7E8</accession>
    <name>A0A0P6X7E8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_08335</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062525.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08335"/>
    <dbReference type="EnsemblBacteria" id="KPL77875">
        <property type="protein sequence ID" value="KPL77875"/>
        <property type="gene ID" value="ADN00_08335"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.669"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="15"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="193"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="392" mass="44279" checksum="2C669D47AC7D968B" modified="2016-01-20" version="1">MNVLVVLTYYRPHTSGLTIYAERLAEAMVKRGHQVTVLTSQFEKNLPREEVRNGVRIVRAPVLFRISKGVIMPSFGWLATKLAKESDLIHLHLPQFDAAGVALRGRLMKKPTVITYHCDLIMPPGALSRLANAAVLVMNEMAGWFTHRIVTYTQDYADNSKYLSRFAKKLKIIQPPVELPETTEDKVRLFSQQHNPERCSPVIGMAARFATEKGVEVLMNALKIVVEKYPRALVQFAGPYQNIIGEEEYFARLEPQLRQFEKAGNWKFMGTLDPEAMAAFYRNIDVLVMSSLNSTEAFGLVQIEAMINGKPCIASNLPGVRQPVKMHEMGLVTPIGDSEALANAIMDVVEHHEKYERDPKPIRTRYLPESVAVAYEELYQEMIEELHITPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7F0</accession>
    <name>A0A0P6X7F0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex</fullName>
            <ecNumber evidence="5">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_03520</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + acetyl-CoA = (R)-N(6)-(S(8)-acetyldihydrolipoyl)-L-lysyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:17017"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:10478"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="ChEBI" id="CHEBI:83111"/>
            <dbReference type="EC" id="2.3.1.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 5">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="5"/>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061583.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03520"/>
    <dbReference type="EnsemblBacteria" id="KPL78975">
        <property type="protein sequence ID" value="KPL78975"/>
        <property type="gene ID" value="ADN00_03520"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.55"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045254">
        <property type="term" value="C:pyruvate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006086">
        <property type="term" value="P:acetyl-CoA biosynthetic process from pyruvate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045257">
        <property type="entry name" value="E2/Pdx1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23151">
        <property type="entry name" value="PTHR23151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="SSF47005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4 5" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="7">
        <location>
            <begin position="2"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="8">
        <location>
            <begin position="126"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL78975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="420" mass="44409" checksum="6384B48EAB834E69" modified="2016-01-20" version="1">MADIVSMPKLGFDMAEGTLVHWVKKVGESVAKGDVLAEIETDKATVEVESSFEGVMARQLVEEKEIVPVGTPIAVIAAPGEEVADVPAPQAEKPGAPKEESAPAAALAPEVAPAVAEAQAGSGMVKASPLAKRMAKDHQLNLAELEGSGPGGRVVKKDVEQALASPKAAAPLAAAVETRAALPPAAWSAAGAPADERVSLNKLRQAIGRRMVESKQTVPHFYLTYDVDAAPLLELRKQVNELLPEEEKTSVNDFLIKAAAVALRRFPNLNASLQGTEVVRHGHVNIGVAVAVEGGLLTVVTRDADQKPVRVISGEVKSLVKRARDGKVRPEDIEGSTFSISNLGMYQVEEFGAIINPPEAAILAVGAARETPVVVNGEVKAGLRMKLTLSVDHRVSDGAEGAQFMQWLKQIIEQPLHLMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X852</accession>
    <name>A0A0P6X852_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_07065</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062281.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07065"/>
    <dbReference type="EnsemblBacteria" id="KPL78231">
        <property type="protein sequence ID" value="KPL78231"/>
        <property type="gene ID" value="ADN00_07065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025302">
        <property type="entry name" value="DUF4162"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13732">
        <property type="entry name" value="DUF4162"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="2"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL78231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="307" mass="34446" checksum="1AF7ED940919D94D" modified="2016-01-20" version="1">MIFAENLTKQFDQFVAVDGVNLDVPQGNVLVLLGPNGAGKTTTVRMLTSILRPTRGMARVAGYDVVKEARQVRSVVGVLTEQHGLYGRMNADEYLDFFGQLYGLERNHSGRRSLELLERFGLAEDRKKRLSSYSKGMRQKLSLARALLHQPPVLLLDEPTSAMDPESARMVRDAISSLRSADRTIVLCTHNLAEAEELADQVAIIRKGRIIRWGELNELKQQLLGPTQFEAMLSRHVDGWQGSLPEGVSLTLREGYRLRFQIRDPQNTNPALLRSLLADQLDVISFQEVPHSLESAYIEAVRLAKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X864</accession>
    <name>A0A0P6X864_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_07195</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062304.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07195"/>
    <dbReference type="EnsemblBacteria" id="KPL78249">
        <property type="protein sequence ID" value="KPL78249"/>
        <property type="gene ID" value="ADN00_07195"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="220" mass="23775" checksum="35F343ED86B1968B" modified="2016-01-20" version="1">MTRRKLALIGVFIILGVVLAACQPLGFGMASKEPVERGGELLADDFSDPRSGWDTWEKETSSAAYTGGGLLLRVKDANRDYITRAHRSFQDVDLYVSAVKLSGTDNNDFGMVCRYQDAENFYALLVSSDGYAGIIKVKDGARSLISGETMQYSDLIKQGTAGNRLRAVCLGSSLALFVNDTILLVAEDADFSKGDVGLIAGGYEEGGVEIFFDDFKALQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X8D8</accession>
    <name>A0A0P6X8D8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CheC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_17280</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064300.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17280"/>
    <dbReference type="EnsemblBacteria" id="KPL71439">
        <property type="protein sequence ID" value="KPL71439"/>
        <property type="gene ID" value="ADN00_17280"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007597">
        <property type="entry name" value="CheC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028976">
        <property type="entry name" value="CheC-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04509">
        <property type="entry name" value="CheC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103039">
        <property type="entry name" value="SSF103039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CheC" evidence="2">
        <location>
            <begin position="109"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL71439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="207" mass="21969" checksum="16D9CF7BF0CCAC01" modified="2016-01-20" version="1">MNLDELLNDNLLVAMQSIVTKGVEQAAEGFSGMLGQSLTVDSPKVKLVDVTEIPSMLGGPENEAVGIYLASEGTMCSQFMLILPYQKALELVDLLMEQPTGTTDKLGSIERSALAEVGNITSTMFLNAIASQTGISSRPTPPAVMVDMVGAILDIIVATTGGIAEKVLLLQTTFNCGDRALNAEFWVVPDPITLKPILEKASQENGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X8H4</accession>
    <name>A0A0P6X8H4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_11185</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11185"/>
    <dbReference type="EnsemblBacteria" id="KPL76584">
        <property type="protein sequence ID" value="KPL76584"/>
        <property type="gene ID" value="ADN00_11185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006450">
        <property type="term" value="P:regulation of translational fidelity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003837">
        <property type="entry name" value="Asp/Glu-ADT_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036113">
        <property type="entry name" value="Asp/Glu-ADT_sf_sub_c"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02686">
        <property type="entry name" value="Glu-tRNAGln"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141000">
        <property type="entry name" value="SSF141000"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="94" mass="10691" checksum="CCD948D609DC5B31" modified="2016-01-20" version="1">MVELAALRLDAQESEYLRQQLNLQLAAIHELESIPLDTGLQITSHGVPYPAELRQPLREDQWQPSPAVERIIAQAPQFEDGYIIVPEIPHKKLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9S3</accession>
    <name>A0A0P6X9S3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">CRISPR-associated protein Csd1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_06175</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062091.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06175"/>
    <dbReference type="EnsemblBacteria" id="KPL78807">
        <property type="protein sequence ID" value="KPL78807"/>
        <property type="gene ID" value="ADN00_06175"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1736"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010144">
        <property type="entry name" value="CRISPR-assoc_prot_Csd1-typ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09709">
        <property type="entry name" value="Cas_Csd1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01863">
        <property type="entry name" value="cas_Csd1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="622" mass="70262" checksum="BCD3EE1B45E3DD6A" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9Z7</accession>
    <name>A0A0P6X9Z7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transport permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_10745</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ABC-2 integral membrane protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062997.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77032">
        <property type="protein sequence ID" value="KPL77032"/>
        <property type="gene ID" value="ADN00_10745"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006648">
        <property type="entry name" value="DrrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00164">
        <property type="entry name" value="ABC2TRNSPORT"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="27"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="141"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="178"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="222"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="7">
        <location>
            <begin position="20"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL77032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="264" mass="29027" checksum="56330115F5A0C784" modified="2016-01-20" version="1">MTRLWKTYGRAILAVAEMTFRHNVMDAFIIFTVLVQPLLIAVMAMWMLGDKGPEMAIFVVVGSGMTGLWSSLLFVSGNSINVERRSGTLETLVGVPTPLEVIVFGKNLADVTQSLVSMVASYLLAALLFGFDLSIQQPLLFVVSLLLAVVAFISFGLIIAPIFVMNPAVQQFQNALEFPVYILSGFLFPIALLPGWTTPLSYLLPPYWAARALHATSSGTGALPEVLLCWGMMLLFSLVYFFLSSRLFKLMLVKARTDATLDME</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAI1</accession>
    <name>A0A0P6XAI1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_15165</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15165"/>
    <dbReference type="EnsemblBacteria" id="KPL72171">
        <property type="protein sequence ID" value="KPL72171"/>
        <property type="gene ID" value="ADN00_15165"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="59" mass="6474" checksum="B1D388455A1B9C4B" modified="2016-01-20" version="1">MPMGTPGYDQVYEGTNYEGEPVRIVSTRALEADESIDLTPSIGENARYFTEGPGYEAMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XB62</accession>
    <name>A0A0P6XB62_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ALP_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_02630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000012">
        <property type="protein sequence ID" value="KPL79429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061408.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000012.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79429">
        <property type="protein sequence ID" value="KPL79429"/>
        <property type="gene ID" value="ADN00_02630"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd10227">
        <property type="entry name" value="ParM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040607">
        <property type="entry name" value="ALP_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042051">
        <property type="entry name" value="ParM-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17989">
        <property type="entry name" value="ALP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ALP_N" evidence="1">
        <location>
            <begin position="8"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="330" mass="36518" checksum="E1D18C651F8F2398" modified="2016-01-20" version="1">MTETMNFGLDLGMGALKLHGNQQSIQLISQVAVNNGPLVGRMLGLGSSRLPLRIALPSRSTFFVDSGAHDSGRPVENLSMDRFAGSPEMLALFYGAFTRLIQRSGDISQPVSITCGLPLDTLSGEEARTTVESIQRWMKADHIWKANDQENHLNVTEVRVTSQPAGALFDYVLDDEGKIVPERRSAYTQEVGIVSIGMNTTELLVVREKVPVQRFTGASTTGVRRLLELVNGQQLYSLGELDTLLRANKLDISQALPIWEREVTGEIEKRWGKAWRRFTAVILVGGGAILLKNSLPYFFNGKGILTDDPVQSIARGLWKLSLFQNHNRKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XB95</accession>
    <name>A0A0P6XB95_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_10635</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062977.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77017">
        <property type="protein sequence ID" value="KPL77017"/>
        <property type="gene ID" value="ADN00_10635"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="214"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="253"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="289"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="318"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="375"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL77017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="400" mass="42009" checksum="CE79EB75B14439A0" modified="2016-01-20" version="1">MRILYLALKDLAQILRDKKSLLFLVAMPIIFTVFMGFAYGQGNQPQDPRLALAVLNLDADGVAAGELVADLQRSTVVRVEPVDAALSESDLQEQVGRNQFAAALIIPQGFSAAALNGGRPQARLVADTSSADGQNASQAVQAAFIRALSSAEIARLTLDAAQSAGLPAGQFDSDGLVHAAETAWQTPALKVERVAPPAAQESQSNPYTQTSPGMLVQFAVFGLITSANVLVLERQSGALQRLQTTSASGAQIIAGHLLAMFVVVFLQQAILVLFGQFAFGVKYLAQPAALLLVMVCVALWAAALGMLIGVLARGEEQVILYAMAAMFLLSALGGAWFHLEATGGLFARIGGLLPSAQAMTAFQNLIVRGLGFSSVLVPAAVMLAYAGGFFGLALLRLRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBE7</accession>
    <name>A0A0P6XBE7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_02030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000007">
        <property type="protein sequence ID" value="KPL80072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80072">
        <property type="protein sequence ID" value="KPL80072"/>
        <property type="gene ID" value="ADN00_02030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="157" mass="16112" checksum="3E0C052B4F339356" modified="2016-01-20" version="1">MVAAAALRSGRQRGRGGRLFSARAGAGSIGGGNAAAPAGAGQPGPGRAAAREPAAARSAAVSRRRADDQGNCRGDGLESAHGDDAHSRRENPLWHADARAGGDARRVPGNLPQQPPGRARQQPGARGQGIRRIYGKFRQFACGNNGQPVGGHLKFIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBJ5</accession>
    <name>A0A0P6XBJ5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_16555</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064152.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16555"/>
    <dbReference type="EnsemblBacteria" id="KPL72083">
        <property type="protein sequence ID" value="KPL72083"/>
        <property type="gene ID" value="ADN00_16555"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004557">
        <property type="term" value="F:alpha-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd14791">
        <property type="entry name" value="GH36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002252">
        <property type="entry name" value="Glyco_hydro_36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="672" mass="77071" checksum="9A60FE5519196C69" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XCX3</accession>
    <name>A0A0P6XCX3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_14900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000036">
        <property type="protein sequence ID" value="KPL73076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063827.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000036.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL73076">
        <property type="protein sequence ID" value="KPL73076"/>
        <property type="gene ID" value="ADN00_14900"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL73076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="141" mass="16167" checksum="5F5E256B54F7CB29" modified="2016-01-20" version="1">MSRVINPESAGKERTRLIKCIVLALRELMQQTEPNSASKDLAAFIAIALQEIHDSIDSSVNAWEKRGYWVKADRFRMEWEWTGRVSRAMKNALLGEDWGEVAGQSALIMQKFFTVQVPARHRLGTPWVGAYQRFLNESKNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDF6</accession>
    <name>A0A0P6XDF6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000003">
        <property type="protein sequence ID" value="KPL80837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01210"/>
    <dbReference type="EnsemblBacteria" id="KPL80837">
        <property type="protein sequence ID" value="KPL80837"/>
        <property type="gene ID" value="ADN00_01210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="203" mass="21912" checksum="D77920A30ACC33B6" modified="2016-01-20" version="1">MLKELLFSLSIFSLLFLGWGSPDTLARPKITQPQPGQAVQGQVAVIGSTNVTGFQSAEIAFSYENGEDANWFLIAALDYPIEDGTITVWDTTGIEDGAYSLRVKVALQDGRSVESVVSGLRVRNYTPIETATPTAPVEGSAVTLETPQAEVVIAPSLTPLPANPAEVSPPALMYSMTWGVVIVLVLFIVVGVYLFFRSLSRRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDJ7</accession>
    <name>A0A0P6XDJ7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidase M20</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_07965</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062458.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07965"/>
    <dbReference type="EnsemblBacteria" id="KPL77813">
        <property type="protein sequence ID" value="KPL77813"/>
        <property type="gene ID" value="ADN00_07965"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.593"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="1">
        <location>
            <begin position="194"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="456" mass="49664" checksum="6F43AB857E921377" modified="2016-01-20" version="1">MDEKDVKIDQYLDANLDGSLAELAALCAQPSVSAQNLGIDDCANLVAEMLKKRGFATEVLPTGGAPVVFGERKGRSGKTLLFYNHYDVQPGEPLELWESPPFQPEIRDGVMYARGVVDDKGHFTSRLFAVDALLNANGGELPCTVKFVLEGEEETSSLHLHDFVVNNKEKLAADACVWEYGGVDHLDQPTQSLGLRGICYVELSVETANQDVHSGLGGSIFPNAAWRLVWALNTLKDENERILIPGFYDDIVPPTNRDLALLDQLPDPAEQYRTQYGLKGFLKGLTGGVALKAAQVFEPTCTICGLTSGYQGPGSKTVLPAKASAKIDFRLVPNQRPEKVLQQLRAHLDQHGFEDIQIEFMGGDTPARTDPDDDFVKLAVATAEEVYQKAVQIEPMSGGSGPSSIFMEHLNLPVISAGVAHPGAQMHAPNENMRVDLYLLGAKHIARLIKRFGDGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDQ3</accession>
    <name>A0A0P6XDQ3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Deoxyguanosinetriphosphate triphosphohydrolase-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_08295</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the dGTPase family. Type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062518.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08295"/>
    <dbReference type="EnsemblBacteria" id="KPL77868">
        <property type="protein sequence ID" value="KPL77868"/>
        <property type="gene ID" value="ADN00_08295"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.661"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016793">
        <property type="term" value="F:triphosphoric monoester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01212">
        <property type="entry name" value="dGTPase_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006261">
        <property type="entry name" value="dNTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023023">
        <property type="entry name" value="dNTPase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026875">
        <property type="entry name" value="PHydrolase_assoc_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13286">
        <property type="entry name" value="HD_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01353">
        <property type="entry name" value="dGTP_triPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD" evidence="2">
        <location>
            <begin position="75"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="382" mass="44531" checksum="C913C04E75597B54" modified="2016-01-20" version="1">MFTREMLEEIEARSLAPYGIHSKDSRGRLYPEDEPDNRTRFQRDRDRVLHTTAFRRLEYKTQVFINYEGDHYRTRLTHTLEVAQIGRSIACALGGNEDLVETICLAHDLGHPAFGHSGETVLNRLMKDHGGFEHNKQSFRIVTELENRYPDFPGLNLSWEVLEGLVKHETEYDVSDARDFNPNLRGGLEAQICNAADELAYTAHDLDDGLRSGMLQVHMLENLELWNLIVASVGWQGNRLDDLERHRLIRRLINLEVHDLLEATDQKIKASGVKSVDELQRLPYNVVCFSEDMHRRNRQLKDFLYNNLYRQYRVMRMSVKAEQIITKLFEAYVNEPLILPKKVQETIQQRGLHRTVCDYIAGMTDRFAIEEYQKLFDPGFLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDW4</accession>
    <name>A0A0P6XDW4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_06665</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000018">
        <property type="protein sequence ID" value="KPL78404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78404">
        <property type="protein sequence ID" value="KPL78404"/>
        <property type="gene ID" value="ADN00_06665"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132992" evidence="2">
        <location>
            <begin position="22"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="144" mass="15691" checksum="542AEE1BC009C2BB" modified="2016-01-20" version="1">MKRFVLFGILLLLLLALPACNGSPTGSESTDSEQPPIAPHVITNSQTPLQSAPPTPIPADEDIIDEAICADAEPDPIAESIASTYEVPYQQIIDWYCAGSSFDDILVALETSLATDIPAETLLSMREEKEWEDIWVEIGFTNDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XEV7</accession>
    <name>A0A0P6XEV7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase family 2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_05580</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78715.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061985.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78715">
        <property type="protein sequence ID" value="KPL78715"/>
        <property type="gene ID" value="ADN00_05580"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1593"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="249"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="281"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="12"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78715.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="328" mass="36405" checksum="F32771D995550366" modified="2016-01-20" version="1">MRNPTSVPRVAVIIPGYRCETTISAVIQSLPDWVASIIYVDDDSPDDALEVVRGLQSSNPRITILQHAANQGVGGAVLSGYREAVAQGADVLVKMDSDGQMDPQYLPKLLQPILEGKADYTKGNRFLHFSKISAMPFLRRLGNVGLSFLVKAASGYWNVFDPTNGYTALHAAVFPLLDCERVDRRFFFESSLLAELGILRAVVRDVPIPARYGKEKSSLSELDALVNFPFRLAKKFLRRILIQYFVRDFSAFSLFLILGLMLMIFGVGWGAYYWWQSIQQGVPATTGTVMIAVLPLMVGIELIIQSIALDIHNVPSEPIQSQFTAGFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XG92</accession>
    <name>A0A0P6XG92_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_18835</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064585.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70100">
        <property type="protein sequence ID" value="KPL70100"/>
        <property type="gene ID" value="ADN00_18835"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="81" mass="9640" checksum="3E2D31F8B95B8405" modified="2016-01-20" version="1">MNQRKIMKTFRRCTPTERRELLQPLVEKAPEEIWEIARDLRKELRIIYPYTMVSEKSIVEMLTLMGLHLAAGTLPTQKERI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XG94</accession>
    <name>A0A0P6XG94_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AAA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05425</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061957.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05425"/>
    <dbReference type="EnsemblBacteria" id="KPL78691">
        <property type="protein sequence ID" value="KPL78691"/>
        <property type="gene ID" value="ADN00_05425"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13401">
        <property type="entry name" value="AAA_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="54"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="274" mass="31120" checksum="A99944373D20B94A" modified="2016-01-20" version="1">MLDTFSDDEWRLARMERLGLKEDPFKLSADPRYLYLGNEHLSVYRQALAVISRRRGLALINGDMGMGKSSLARRLYDLYASEDGVEICYIHTAAFKSAMDAARQISNALNVPPQRSFQRQMEGLEKKVAEAYTANRNVVVLLDDAQLMSAEALEVIHRLYNFDYDSKVVQVLAFGQREIIPLFEANKAVNARVFVRLVLPPLTLASALQMVIFRLRVAGRSEPLIDDDAFELLYERSDGVPREIIRLCALATDYLLTSDEPFINLDIVQEVIEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGF2</accession>
    <name>A0A0P6XGF2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">LMWPc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_18120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18120"/>
    <dbReference type="EnsemblBacteria" id="KPL70164">
        <property type="protein sequence ID" value="KPL70164"/>
        <property type="gene ID" value="ADN00_18120"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2927"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023485">
        <property type="entry name" value="Ptyr_pPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036196">
        <property type="entry name" value="Ptyr_pPase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01451">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00226">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52788">
        <property type="entry name" value="SSF52788"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LMWPc" evidence="1">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="122" mass="13610" checksum="31AD0C697990B43F" modified="2016-01-20" version="1">MAEAIVNDRMADIWQAVSAGTQPAGYIHPNALLVLREIGIDHRGFSKSVDDFRDIEFDLVVTVCDDAAETCPMWLGRGKKVHMGFIDPAKAVGSEEEVLVVFRSVRDQILEKIPQLLRENES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XH53</accession>
    <name>A0A0P6XH53_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_02675</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000012">
        <property type="protein sequence ID" value="KPL79437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061416.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000012.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02675"/>
    <dbReference type="EnsemblBacteria" id="KPL79437">
        <property type="protein sequence ID" value="KPL79437"/>
        <property type="gene ID" value="ADN00_02675"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2363"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050797">
        <property type="term" value="F:thymidylate synthase (FAD) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006231">
        <property type="term" value="P:dTMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.170">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003669">
        <property type="entry name" value="Thymidylate_synthase_ThyX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036098">
        <property type="entry name" value="Thymidylate_synthase_ThyX_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34934">
        <property type="entry name" value="PTHR34934"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02511">
        <property type="entry name" value="Thy1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69796">
        <property type="entry name" value="SSF69796"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51331">
        <property type="entry name" value="THYX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="473" mass="53875" checksum="0DB06A0A0D16647A" modified="2016-01-20" version="1">MPNPRQIYLLDPQKLSPETIAVAFAKTSRSPESFQQIAQELSEEKSAQFHEKWVVGYGHSSVAEHAVLHIAVENISRLAVETLESCRLASYTEKSTRYQKWKNDQFHTPMELENHPLKEIYTKTVRGLFEAYQSALPKVQQVVAAKIPRKPGESEETWERRVRSEIVDSCRYFLPAAALANVGVSINARALEHSLQKMLSHPLEEVRQMGAQIKEVAQQNAPTLVKYAEPDHRIEQLQKDLTRIASQVPSPSSSSDWCELVHWDQDAEDRALAAALYRFNSIGYTQNTDFIGTLSHPQKQDLAAQILSGLGRHDIPLRELEYASYTFDLVLDQGAYFEFKRHRMMTQTAQALTTCLGYAVPRLLVEAGLENAYRAAMHSAASAYEQLYRFNPHVAAYVVPNGYNRRVLFCTNLRSADHLINLRTAPNAHYAIRRVAQRIAEQIRTVTPLLGQHLRCCSDETWQQIEHDYFTQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XIV1</accession>
    <name>A0A0P6XIV1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Epimerase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_02005</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000007">
        <property type="protein sequence ID" value="KPL80068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061292.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000007.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80068">
        <property type="protein sequence ID" value="KPL80068"/>
        <property type="gene ID" value="ADN00_02005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="328" mass="36181" checksum="C488A04DD56213C2" modified="2016-01-20" version="1">MKIFITGGTGFIGGYVTRRLAQDGHELVCLARPTSQRGALQAVGAQIVEGDVFDNEALAQGMRGCQAVIHLANVYSFWEKDPTVYRRVNVEGTRNVMLAALEAGAQKVIHVSSAVIYGKPTVSPYTEDTPFGPERFSAYAESKYEGDRLVWDLHRQRGLPVVGIYPAAVIGAGDLKASGMFVVNVLKHRLPAVGLKNSRITFVPARDVAEAIALALRAQYNVGERYLIGKHTLCLEEYLKTVSEISGERLPLIWLPDGVVVGLARALTWLADRTRRPPLWGMSNDQTRTFLEGFACDGSKAERELGLTYSPLRPAFEEAVRWVREHVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XJR7</accession>
    <name>A0A0P6XJR7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Amidohydro_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_11825</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063222.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11825"/>
    <dbReference type="EnsemblBacteria" id="KPL76038">
        <property type="protein sequence ID" value="KPL76038"/>
        <property type="gene ID" value="ADN00_11825"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01300">
        <property type="entry name" value="YtcJ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013108">
        <property type="entry name" value="Amidohydro_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033932">
        <property type="entry name" value="YtcJ-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07969">
        <property type="entry name" value="Amidohydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro_3" evidence="1">
        <location>
            <begin position="47"/>
            <end position="524"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="527" mass="57443" checksum="CF44FBF499B888A2" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XK68</accession>
    <name>A0A0P6XK68_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_01650</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061220.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01650"/>
    <dbReference type="EnsemblBacteria" id="KPL80574">
        <property type="protein sequence ID" value="KPL80574"/>
        <property type="gene ID" value="ADN00_01650"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04188">
        <property type="entry name" value="DPG_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035518">
        <property type="entry name" value="DPG_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="9"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL80574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="246" mass="28060" checksum="34519C47136FDF41" modified="2016-01-20" version="1">MALDKPFLSIIIPAHNEENRLPQTLEEIDRFIQSQAYAVEVLVIENGSRDRTFELAREYAARMPFLHVFQETARGKGLAVKRGMLEARGDYRFICDADLSMPIAEVNRFLPPQLQDPHVVIGSREAPGAVRYNEPAYRHFIGRIFNMMVRVLALPGLQDTQCGFKLFSAEVAEKVFPLQTLAGMSFDVEVLYIARMMGYPIVEVAIPWYFSAESRVRLFEDSMRMAGDLLTIRRNARQGVYSPVPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XK81</accession>
    <name>A0A0P6XK81_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Oligoendopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_01755</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase M3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061239.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80592">
        <property type="protein sequence ID" value="KPL80592"/>
        <property type="gene ID" value="ADN00_01755"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045090">
        <property type="entry name" value="Pept_M3A_M3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001567">
        <property type="entry name" value="Pept_M3A_M3B_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011976">
        <property type="entry name" value="Pept_M3B_oligopep-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804">
        <property type="entry name" value="PTHR11804"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01432">
        <property type="entry name" value="Peptidase_M3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02289">
        <property type="entry name" value="M3_not_pepF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase_M3" evidence="7">
        <location>
            <begin position="165"/>
            <end position="556"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL80592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="574" mass="65837" checksum="B120D602B26872A5" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKJ1</accession>
    <name>A0A0P6XKJ1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_11420</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063143.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11420"/>
    <dbReference type="EnsemblBacteria" id="KPL76559">
        <property type="protein sequence ID" value="KPL76559"/>
        <property type="gene ID" value="ADN00_11420"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.984"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="62"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="98"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="174"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="238"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="331"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="369"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="408"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="437"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="483"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="541"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="64"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="370"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL76559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="575" mass="63246" checksum="09E8BCD4BD4BB406" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKJ8</accession>
    <name>A0A0P6XKJ8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PTS EIIA type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_11525</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063162.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11525"/>
    <dbReference type="EnsemblBacteria" id="KPL76577">
        <property type="protein sequence ID" value="KPL76577"/>
        <property type="gene ID" value="ADN00_11525"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00211">
        <property type="entry name" value="PTS_IIA_fru"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016152">
        <property type="entry name" value="PTrfase/Anion_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002178">
        <property type="entry name" value="PTS_EIIA_type-2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00359">
        <property type="entry name" value="PTS_EIIA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55804">
        <property type="entry name" value="SSF55804"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51094">
        <property type="entry name" value="PTS_EIIA_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PTS EIIA type-2" evidence="1">
        <location>
            <begin position="4"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="158" mass="17527" checksum="EA238E008056FDBC" modified="2016-01-20" version="1">MATDILSNIEVLNLNHATSREEVLTVMSKVVIEKGYATPGFLNAVLERERNYPTGLHTRGVEVAIPHADPEWTLKPSLTVGVLQNAVEFEPMGGEGDMVQARLIFLLTIADPSEHLNFLKAFATLVEDEDTLVEFEKNPDIHYLLGRLQSALQAETTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XLC8</accession>
    <name>A0A0P6XLC8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ferredoxin oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_00790</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061102.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00790"/>
    <dbReference type="EnsemblBacteria" id="KPL81095">
        <property type="protein sequence ID" value="KPL81095"/>
        <property type="gene ID" value="ADN00_00790"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3556"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016903">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07034">
        <property type="entry name" value="TPP_PYR_PFOR_IOR-alpha_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.920.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022367">
        <property type="entry name" value="2-oxoacid/accept_OxRdtase_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019752">
        <property type="entry name" value="Pyrv/ketoisovalerate_OxRed_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002880">
        <property type="entry name" value="Pyrv_Fd/Flavodoxin_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002869">
        <property type="entry name" value="Pyrv_flavodox_OxRed_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01558">
        <property type="entry name" value="POR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01855">
        <property type="entry name" value="POR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53323">
        <property type="entry name" value="SSF53323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03710">
        <property type="entry name" value="OAFO_sf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="POR" evidence="2">
        <location>
            <begin position="28"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="POR_N" evidence="3">
        <location>
            <begin position="227"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL81095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="610" mass="68196" checksum="2A4C7104CADFF13E" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XLF3</accession>
    <name>A0A0P6XLF3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10640</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063046.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10640"/>
    <dbReference type="EnsemblBacteria" id="KPL77080">
        <property type="protein sequence ID" value="KPL77080"/>
        <property type="gene ID" value="ADN00_10640"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2602"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003719">
        <property type="entry name" value="Phenazine_PhzF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13774">
        <property type="entry name" value="PTHR13774"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02567">
        <property type="entry name" value="PhzC-PhzF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016184">
        <property type="entry name" value="PhzC_PhzF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00654">
        <property type="entry name" value="PhzF_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="1">
        <location>
            <position position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR016184-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="267" mass="29474" checksum="74714DE6B99283A5" modified="2016-01-20" version="1">MKTPIYQVDAFTSQPFSGNPAAVCLLTSQRSDEWMLNTAREMNLSETAFLLPEGDGYRLRWFTPALEVDLCGHATLASAHILWETGKLPPEEPARFYTRSGLLTARKVANRVELDFPARPMQPAELPDGLAAALGIPAPRAAAWHAQGENFLIELDSEAPVRAAQPNFDQLKAYPIHGVILTSEATQSTRYDFVSRFFAPRWGVNEDPVTGSAHCYLAPYWSERMGKTVFSAYQASARGGELRVRLDGERVFISGEAVTVLSGSLHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XLP5</accession>
    <name>A0A0P6XLP5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transport permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_12090</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ABC-2 integral membrane protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063273.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12090"/>
    <dbReference type="EnsemblBacteria" id="KPL76078">
        <property type="protein sequence ID" value="KPL76078"/>
        <property type="gene ID" value="ADN00_12090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3894"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="127"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="163"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="254"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="7">
        <location>
            <begin position="36"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL76078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="283" mass="32027" checksum="4B1EF284ADE9C8E1" modified="2016-01-20" version="1">MNNQPIIKKDPFITVIRPKKALSALDLKEMWLFRELVYFLTWRDLKVRYKQTLLGVLWAVLNPFLTMVVFSIFFGDLANVPSDGVPYPIFAYTALLPWTLFSNALSVASRSLVNNRHMITKVYFPRVILPLSSVLSGLVDFFIASLILVGLMFYYGYGLTANAWTIIPLLLLTLVTSIGVGLWLSAANVLYRDVNYITPFLTQFWMFITPIAYGASLLPEKWQLVYALNPMAGVVEGFRWALLGTEQGAPGPRLIISSAVALFALISGMIYFRRMERQFADMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XLS3</accession>
    <name>A0A0P6XLS3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_12305</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063313.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12305"/>
    <dbReference type="EnsemblBacteria" id="KPL76115">
        <property type="protein sequence ID" value="KPL76115"/>
        <property type="gene ID" value="ADN00_12305"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3941"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="65"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="104"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="127"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="162"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="656"/>
            <end position="694"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL76115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="790" mass="85630" checksum="7A1F3A63356337CE" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XLW0</accession>
    <name>A0A0P6XLW0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HTH lacI-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_09210</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09210"/>
    <dbReference type="EnsemblBacteria" id="KPL77300">
        <property type="protein sequence ID" value="KPL77300"/>
        <property type="gene ID" value="ADN00_09210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL77300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="325" mass="36185" checksum="777CA55ED3398AEF" modified="2016-01-20" version="1">MSRVINDHPDVSDETRLKIQDIINDLGYSPNIIARSLSRGKTNTLGIVGFRLDFFGSSSVLMAVERKARELGFSMLLTLLNEIDDLDVDFILENLVSRQVDGLIWTVPGKLDEANFIMQKTRELPIPVVILNHNPDERHNFVCLDNCYGGKIATQHLLDEGYRQVGIITGPSGWWESEERAKGWREALGYADPWSVPADLVEEGDWSSQSGEKAFNNLIEKNPQINAVFACNDQMALGAYRAAQKRGMDIPSDIGLIGFDNIPEAAFFTPPLSSVNQNCWDLGAGAVTRLMELLKNPKAEKGSVIWVKPQLVVRESSLRKDQSLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XLY3</accession>
    <name>A0A0P6XLY3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_01260</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000003">
        <property type="protein sequence ID" value="KPL80845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061148.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01260"/>
    <dbReference type="EnsemblBacteria" id="KPL80845">
        <property type="protein sequence ID" value="KPL80845"/>
        <property type="gene ID" value="ADN00_01260"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038109">
        <property type="entry name" value="DNA_bind_recomb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011109">
        <property type="entry name" value="DNA_bind_recombinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006119">
        <property type="entry name" value="Resolv_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036162">
        <property type="entry name" value="Resolvase-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025827">
        <property type="entry name" value="Zn_ribbon_recom_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07508">
        <property type="entry name" value="Recombinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00239">
        <property type="entry name" value="Resolvase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13408">
        <property type="entry name" value="Zn_ribbon_recom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00857">
        <property type="entry name" value="Resolvase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53041">
        <property type="entry name" value="SSF53041"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51737">
        <property type="entry name" value="RECOMBINASE_DNA_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51736">
        <property type="entry name" value="RECOMBINASES_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Resolvase/invertase-type recombinase catalytic" evidence="1">
        <location>
            <begin position="5"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="Recombinase" evidence="2">
        <location>
            <begin position="159"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL80845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="384" mass="44435" checksum="071CD125D0A24628" modified="2016-01-20" version="1">MKTKRAIIYVRVSNDEQTKGYSLKTQIEGCENYANELGYSVVATFQEDYTGTVLDRPTLNEVRQFILDDKEIDAMIVYDLDRMARRSVHQMILEEELLRLGVIVEYVIGRYEDSDEGRLQKQIRASIAEYEKAKILERSKRGKRGKAKSGFVLVGSRPPYGYKSISEPHKTWLVIDEDEAKVVKMVYDWFLIGDGDENPLSIRAIAFKLTELGIPTRGDKVKHVAKKFGHGVWQAAMVSHILKNETYTGTWHFGKTKMVNDGKESTRKLKSKRGLGKQISRSKDEWISVPVPAIIDLITFKLAQNRFEVNKAHSCGPKPEHQYLMGKRLKCNRYNYGYRGQYRRNGNWYYLCNGRRQVVSRCDMPSFSGRLVDETVWDWVKTNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XMA9</accession>
    <name>A0A0P6XMA9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_18540</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FemABX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064533.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18540"/>
    <dbReference type="EnsemblBacteria" id="KPL70055">
        <property type="protein sequence ID" value="KPL70055"/>
        <property type="gene ID" value="ADN00_18540"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3016"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016755">
        <property type="term" value="F:aminoacyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044038">
        <property type="term" value="P:cell wall macromolecule biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003447">
        <property type="entry name" value="FEMABX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02388">
        <property type="entry name" value="FemAB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51191">
        <property type="entry name" value="FEMABX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="186"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL70055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="367" mass="41848" checksum="906075921720AC7A" modified="2016-01-20" version="1">MTQATDWNARIAALPGANILQTSQWAQLKRITGWEAIYRTWESPDGKLEAAALILLRDLRLAGGLVRLRVMYVPRGPLLDWGNENLRKRVLDDLQHLAAEKKAIFIKLDADVEIASGVPGEADERENLVGASTVTELRQRGWLFSQEQIQFRNTVLIDLRAAEEELLARMKQKTRYNIRLAAKKGVVVRKGGVEDLPGLYRMYAETSLRDGFVIRDESYYRALWEIFLQAGMLTPLIAEVEGEAVAALMLFHFAGKAWYIHGMSREAHREKMPNYLLQWEAMRRAKAAGCQEYDLWGAPDEFHESDGMWGVFRFKEGLGGRVSRTLGAWDYPAKAVIYPLYTRVLPRLLDVMRRRGKEKTRQQAGLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XMF9</accession>
    <name>A0A0P6XMF9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_18890</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064597.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70110">
        <property type="protein sequence ID" value="KPL70110"/>
        <property type="gene ID" value="ADN00_18890"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="65"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL70110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="120" mass="13648" checksum="A632EB17B74738E6" modified="2016-01-20" version="1">MPPTAGQNYSMQTQINALKESMEKGFDEIKRMIRDFDVRVREVENREAACQPVVQQRLDAAWRKIDEHSTQIKEQDARLDAMNNLITKLEQANTLLVWLLGILGAAVIGWLVTQILKGIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XMG9</accession>
    <name>A0A0P6XMG9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_18940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064607.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70119">
        <property type="protein sequence ID" value="KPL70119"/>
        <property type="gene ID" value="ADN00_18940"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="129" mass="14498" checksum="6AF59F40CB657294" modified="2016-01-20" version="1">MSIRISDLVQEERTITIMVGDEELSVTYRPKAYTPLVEDQMQSLMESNRPGNGLAQMLSHILINWDVVDENNKPIETTFENIRKFPVALLTLITQEINKDNRAGDEDRKNSGGGSRRGAKSDSVRTGSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XMX2</accession>
    <name>A0A0P6XMX2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH luxR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_11500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76572">
        <property type="protein sequence ID" value="KPL76572"/>
        <property type="gene ID" value="ADN00_11500"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041617">
        <property type="entry name" value="TPR_MalT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17874">
        <property type="entry name" value="TPR_MalT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="869"/>
            <end position="934"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL76572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="936" mass="105674" checksum="735D3D6BFD144033" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XN24</accession>
    <name>A0A0P6XN24_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 14">Crossover junction endodeoxyribonuclease RuvC</fullName>
            <ecNumber evidence="11 14">3.1.21.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13 14">Holliday junction nuclease RuvC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12 14">Holliday junction resolvase RuvC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">ruvC</name>
        <name evidence="15" type="ORF">ADN00_08165</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 14">Nuclease that resolves Holliday junction intermediates in genetic recombination. Cleaves the cruciform structure in supercoiled DNA by nicking to strands with the same polarity at sites symmetrically opposed at the junction in the homologous arms and leaves a 5'-terminal phosphate and a 3'-terminal hydroxyl group.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 14">
            <text>Endonucleolytic cleavage at a junction such as a reciprocal single-stranded crossover between two homologous DNA duplexes (Holliday junction).</text>
            <dbReference type="EC" id="3.1.21.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="14">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 14">Belongs to the RuvC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.21.10" evidence="11 14"/>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062495.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08165"/>
    <dbReference type="EnsemblBacteria" id="KPL77848">
        <property type="protein sequence ID" value="KPL77848"/>
        <property type="gene ID" value="ADN00_08165"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.634"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008821">
        <property type="term" value="F:crossover junction endodeoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16962">
        <property type="entry name" value="RuvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00034">
        <property type="entry name" value="RuvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020563">
        <property type="entry name" value="X-over_junc_endoDNase_Mg_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002176">
        <property type="entry name" value="X-over_junc_endoDNase_RuvC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30194">
        <property type="entry name" value="PTHR30194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02075">
        <property type="entry name" value="RuvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00696">
        <property type="entry name" value="RSOLVASERUVC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00228">
        <property type="entry name" value="ruvC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01321">
        <property type="entry name" value="RUVC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 14" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 14" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="8 14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 14" id="KW-0540">Nuclease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="14">
        <location>
            <position position="7"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00025073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00029354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00030973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KPL77848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="168" mass="18460" checksum="39135400BA285792" modified="2016-01-20" version="1">MRVLGIDPGTATTGFGLVDETERGELVVADYGVIETQAGTPMELRLLELYHKMQELLFLHRPERGAVEKLFFQRNVTTAISVGQARGVILLALAESNIPVAEYAPLEIKMAITGYGVADKKQMQQMVQSLLRMPKLPKPDDAADALAVAICHLHRYRLDDLSLMGGAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XPU0</accession>
    <name>A0A0P6XPU0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_05480</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061967.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05480"/>
    <dbReference type="EnsemblBacteria" id="KPL78699">
        <property type="protein sequence ID" value="KPL78699"/>
        <property type="gene ID" value="ADN00_05480"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="130" mass="13939" checksum="F22410B6601F797D" modified="2016-01-20" version="1">MPQLEKGGKWVFGWSIVGVGGEIAIPPAAFSEYGFRVGSEVLFLRGSRRSGGLIIGLPERLAQSKISLQSRVIEQGCIEAGGRIKIPEIAGVNPGSRLLVVRGSRLALSFLAYGPIVEIAQNHPEIEIFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQ25</accession>
    <name>A0A0P6XQ25_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_09540</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062759.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77349">
        <property type="protein sequence ID" value="KPL77349"/>
        <property type="gene ID" value="ADN00_09540"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01547">
        <property type="entry name" value="SBP_bac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133167" evidence="2">
        <location>
            <begin position="22"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="26"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="455" mass="50292" checksum="731CBA92636FA4CB" modified="2016-01-20" version="1">MYAKKVIAILLFAAVLLGACAPTTPVSTEVSNAPAQPAQPTQAEQPAEAPEQPTEEAKPVVVSVWVTDAPAVRKAAEEYEKLTGKKVIVEEIAREVLQEKEKTELTSKTGAYDLLWVPSEWVAELAEGQLLEPLNPYMENSSLPQPDQADWASPGAVEAYNYKGNLYGFPVALDTVFLYYRTDLIEKAPETWDEYLQVAKEQTNDQRYGATLFGKLPESIAWDFINYFWSFGGEILDENFRPTVNSPEGVASLTYFTDLLNKEQVVSPGVSTYEYPEVLAAFQQDKAAMVLQWNAAYADFGNPEASPAIYDKFNATVLPGKQMEDGTINRKVIGHVWGFVMNASSQNKEEAYSFLVYLTGKEGLKYFPTDGASINVNSKAVLSDPAMIEAHPEFELLNESFQYLQLWPTTTATSQIILTIAQEASSALVGSKTPQQAMDDANKAIDDLMQQAGYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQA9</accession>
    <name>A0A0P6XQA9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chemotaxis protein CheY</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_03275</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061533.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03275"/>
    <dbReference type="EnsemblBacteria" id="KPL78936">
        <property type="protein sequence ID" value="KPL78936"/>
        <property type="gene ID" value="ADN00_03275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="4"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="127" mass="14073" checksum="56ABBBD93553044D" modified="2016-01-20" version="1">MAKKILIAEDEADIRALIEFTLKFAGFDVVTAKNGLEALEAAQAELPDLILLDVRMPQMTGYEACEAIKSDPDIRHIPVVFLSAKGQEKEILAGLEAGATEYLLKPFAPDELARRITELLEQYSRLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XRC0</accession>
    <name>A0A0P6XRC0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fe-S cluster protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_15365</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063918.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15365"/>
    <dbReference type="EnsemblBacteria" id="KPL72204">
        <property type="protein sequence ID" value="KPL72204"/>
        <property type="gene ID" value="ADN00_15365"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.775"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06664">
        <property type="entry name" value="IscU_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002871">
        <property type="entry name" value="NIF_FeS_clus_asmbl_NifU_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10093">
        <property type="entry name" value="PTHR10093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01592">
        <property type="entry name" value="NifU_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NifU_N" evidence="1">
        <location>
            <begin position="5"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="134" mass="14684" checksum="ED822F2D721921CF" modified="2016-01-20" version="1">MDDLYRQVIIERNKNPLYRGELEPCDIRFEDENPLCGDQIRIDLRVDKNDVVTEAAFSGHGCAISTASADLLLESIIGKPLDEIRALGKEDILDLLGIDLGPVRLKCALLSLKVLKAGVYGLSEASDSLVEDEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XRF1</accession>
    <name>A0A0P6XRF1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_15595</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063957.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72240">
        <property type="protein sequence ID" value="KPL72240"/>
        <property type="gene ID" value="ADN00_15595"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="91" mass="10842" checksum="4E940EB46C2F227E" modified="2016-01-20" version="1">MKLRGFYTKNYLNYQIEKRKKELEETVLLDHNLVKLANIGNTPTGDPEMGEMARVVITDVYLVISTLAQEILRLRNERKYWMERRSPTKRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XRK3</accession>
    <name>A0A0P6XRK3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BPL/LPL catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_08415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08415"/>
    <dbReference type="EnsemblBacteria" id="KPL77888">
        <property type="protein sequence ID" value="KPL77888"/>
        <property type="gene ID" value="ADN00_08415"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.685"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03099">
        <property type="entry name" value="BPL_LplA_LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="1">
        <location>
            <begin position="14"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="253" mass="27812" checksum="0FD4A8DBE91FC60F" modified="2016-01-20" version="1">MAVDEAILDHVGAGLSLPTLRLYTWQPGCLSLGFSQPVSHANQQALQQHGWHLVRRPTGGQAVLHIDELTYAVIAPLDEPRVKGSVLTAYRNLSLGLLAALRILGLQPTADSVYVQEQENSRDPACFQNPSNYEITVKGYKLVGSAQARRADGVLQHGSIPIFGEITRVLFCLSRVQNLSTAQEQLRRHAANLESILGKAPDLTAVQAALVEGFASALNLNFTPPQTLTRREEIRAEELARTKYQSDRWTARV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XT01</accession>
    <name>A0A0P6XT01_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_12260</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76107">
        <property type="protein sequence ID" value="KPL76107"/>
        <property type="gene ID" value="ADN00_12260"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="140" mass="14788" checksum="3600F75324B00279" modified="2016-01-20" version="1">MFEPLAAKALQRVQHAVDGCYIAAQQITKGAFLLADETLAPGAVGQLTEKGFEGAPVVHAKGAVEEGAVDGFAVERQGGGPGAVVQVAGVDQHAVHVPQNGLYGWVCHVNLRVCKLRWIVVSAWQIVKRVEVIGVTPVKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XU60</accession>
    <name>A0A0P6XU60_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ferrous iron transport protein B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">ADN00_05255</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Probable transporter of a GTP-driven Fe(2+) uptake system.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061924.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05255"/>
    <dbReference type="EnsemblBacteria" id="KPL78665">
        <property type="protein sequence ID" value="KPL78665"/>
        <property type="gene ID" value="ADN00_05255"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1525"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015093">
        <property type="term" value="F:ferrous iron transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055072">
        <property type="term" value="P:iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003373">
        <property type="entry name" value="Fe2_transport_prot-B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011640">
        <property type="entry name" value="Fe2_transport_prot_B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041069">
        <property type="entry name" value="FeoB_Cyto"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011642">
        <property type="entry name" value="Gate_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07664">
        <property type="entry name" value="FeoB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17910">
        <property type="entry name" value="FeoB_Cyto"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07670">
        <property type="entry name" value="Gate"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00437">
        <property type="entry name" value="feoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0410">Iron transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="193"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="238"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="272"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="304"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="367"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="520"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="550"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="domain" description="FeoB_Cyto" evidence="12">
        <location>
            <begin position="17"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="Gate" evidence="11">
        <location>
            <begin position="202"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="FeoB_C" evidence="10">
        <location>
            <begin position="306"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="Gate" evidence="11">
        <location>
            <begin position="364"/>
            <end position="548"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF07664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF17910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KPL78665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="579" mass="63852" checksum="AA3717BDBB772181" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XW48</accession>
    <name>A0A0P6XW48_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_08690</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000022">
        <property type="protein sequence ID" value="KPL77661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062603.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000022.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08690"/>
    <dbReference type="EnsemblBacteria" id="KPL77661">
        <property type="protein sequence ID" value="KPL77661"/>
        <property type="gene ID" value="ADN00_08690"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007318">
        <property type="entry name" value="Phopholipid_MeTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04191">
        <property type="entry name" value="PEMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="132"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL77661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="205" mass="22968" checksum="0457DDBDEA5F22B7" modified="2016-01-20" version="1">MLQSGFVWILLGFVMFGGLHSLLASLRAKALAARWFGDAGRLGYRLFFNLSALISFAPILALVALLPDRRIYAIPLPWALLTGALQLAAALGMLVSVLQTHPLHFLGLEQLTRPESAGDHPRELVVRGAYRYVRHPLYFFSLVILWLSPLMSWNVLAFNLGATAYMALGAWLLEEPKLIQAFGEQYRAYRQSTPMLIPLIKFSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XX47</accession>
    <name>A0A0P6XX47_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_00835</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061053.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL81103">
        <property type="protein sequence ID" value="KPL81103"/>
        <property type="gene ID" value="ADN00_00835"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL81103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="221" mass="24527" checksum="5FEFC9FA0450BAB3" modified="2016-01-20" version="1">MESTPSSENPRRFSLSDILFAPIGCLIQSSPLFVFLVILVAGTIGSIVFYSTNTDFWGLTAPDFEHFTVSDNFQTIQGTEEQTWKISYEFAGATQFSGLVRHVSPIRMGKFPMLTHDILVTSGDFADSSLVRTNVSNHHFTWFCDSGTQPRGTINLLHTVPASEEIYEQLLQIRSGDQVAISGREILRIDSLKPDGSSDGWWQDSGCNTLLVNTVEILAEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XXV7</accession>
    <name>A0A0P6XXV7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidase_MA_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_01240</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000003">
        <property type="protein sequence ID" value="KPL80841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061144.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01240"/>
    <dbReference type="EnsemblBacteria" id="KPL80841">
        <property type="protein sequence ID" value="KPL80841"/>
        <property type="gene ID" value="ADN00_01240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039568">
        <property type="entry name" value="Peptidase_MA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13485">
        <property type="entry name" value="Peptidase_MA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133273" description="Peptidase_MA_2 domain-containing protein" evidence="2">
        <location>
            <begin position="24"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="369"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_MA_2" evidence="3">
        <location>
            <begin position="155"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL80841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="392" mass="43625" checksum="545E922193D1A878" modified="2016-01-20" version="1">MRKILLCCWIALFLFTTASPASAQGTVTFGEIQTNYNFGDQAVFQADLNTSESVQEIVLFLEQPGEDTLVRPAVITQNSQAETVLDLKEYPLRPFAQITCYFRLKTLDGQSFESNRATFHYTDNRFNWDLLEDEDFQVYWYGRGITFGQSVLNVARAGLESAQRYINAPMPQPLQIYVYDNAADLQSALSLGLQNAWVAGHASPDLNTVLVSIPSGPQQQLELERQIPHEIAHILQYSLVGDKYAQMPVWLLEGTASLAELYPNPDYPRAIVDAVESGSLLAFDSLCITFPRDASGAFLAYAQSESFIRFLYRTYGTSGLSGLFEAYSDGLGCEEGAHAALNTGLDELEYRWQQSALGINSEWLVVRNLSPYLLLLAVLLVPPLAVGLTKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XY44</accession>
    <name>A0A0P6XY44_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_00370</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="6">Binds 1 [2Fe-2S] cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I 24 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060971.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00370"/>
    <dbReference type="EnsemblBacteria" id="KPL81033">
        <property type="protein sequence ID" value="KPL81033"/>
        <property type="gene ID" value="ADN00_00370"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03064">
        <property type="entry name" value="TRX_Fd_NuoE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1590">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028431">
        <property type="entry name" value="NADP_DH_HndA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002023">
        <property type="entry name" value="NuoE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042128">
        <property type="entry name" value="NuoE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041921">
        <property type="entry name" value="NuoE_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43342:SF2">
        <property type="entry name" value="PTHR43342:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000216">
        <property type="entry name" value="NADH_DH_24kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="5 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000216-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL81033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="168" mass="18663" checksum="EBAE489A78A91C3B" modified="2016-01-20" version="1">MKTDIIERNAPPTDDRRWKIVDATMKKHNYSPKSLIETLHAVQDAFGYIDDEALKYVSDSLHVPPSKAYGVTTFYNSFTMKPAGEHVILLCTGTACYVKGTDKILEYMKNEYDLEPGQTTADNKVSLLSARCVGACGLAPVMVLDGSVVGRLSVEDMQNKIREWINNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XY84</accession>
    <name>A0A0P6XY84_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_00920</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061069.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00920"/>
    <dbReference type="EnsemblBacteria" id="KPL81116">
        <property type="protein sequence ID" value="KPL81116"/>
        <property type="gene ID" value="ADN00_00920"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="433"/>
            <end position="645"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL81116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="649" mass="71975" checksum="9F8F5DF3700C5668" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y343</accession>
    <name>A0A0P6Y343_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_03065</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000014">
        <property type="protein sequence ID" value="KPL79325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061491.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000014.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03065"/>
    <dbReference type="EnsemblBacteria" id="KPL79325">
        <property type="protein sequence ID" value="KPL79325"/>
        <property type="gene ID" value="ADN00_03065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HDc" evidence="1">
        <location>
            <begin position="27"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="191" mass="21053" checksum="B61133CE580E1C1A" modified="2016-01-20" version="1">MIQLGERFRLALVFASRLHEDQARKGSGVPYLSHLLAVTSLVLENGGDEDEAIAALLHDAVEDRGGNEVLEQIRGGFGARVAEIVKGCSDCEGSPKPPWRERKEAHLKHLAGANGSVLLVTSADKLHNARCYLADYREQGEALWPRFRGGKDGTLWYLRSFVELARERGPRKLVAELDLVVSELERLAGQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y5H5</accession>
    <name>A0A0P6Y5H5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Beta sliding clamp</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">ADN00_01570</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Forms a ring-shaped head-to-tail homodimer around DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the beta sliding clamp family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061205.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01570"/>
    <dbReference type="EnsemblBacteria" id="KPL80559">
        <property type="protein sequence ID" value="KPL80559"/>
        <property type="gene ID" value="ADN00_01570"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009360">
        <property type="term" value="C:DNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00140">
        <property type="entry name" value="beta_clamp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001001">
        <property type="entry name" value="DNA_polIII_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022635">
        <property type="entry name" value="DNA_polIII_beta_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022637">
        <property type="entry name" value="DNA_polIII_beta_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022634">
        <property type="entry name" value="DNA_polIII_beta_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30478">
        <property type="entry name" value="PTHR30478"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00712">
        <property type="entry name" value="DNA_pol3_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02767">
        <property type="entry name" value="DNA_pol3_beta_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02768">
        <property type="entry name" value="DNA_pol3_beta_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000804">
        <property type="entry name" value="DNA_pol_III_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00480">
        <property type="entry name" value="POL3Bc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00663">
        <property type="entry name" value="dnan"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 9" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="5 9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA_pol3_beta" evidence="10">
        <location>
            <begin position="1"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_pol3_beta_2" evidence="11">
        <location>
            <begin position="130"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_pol3_beta_3" evidence="12">
        <location>
            <begin position="249"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KPL80559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="375" mass="40205" checksum="F83FD0C1AB169A6B" modified="2016-01-20" version="1">MKVSVSQQQLAHGLSVVSRAVSPRSTLPVLSNILVATDEGRLRLSATNLELGISCWIGAQISEEGAVTVPSRTFSDLINTLPNETVLLDLNEKTQTLNVRCASSNTDIKGIDAQEFPPMPVPDLSAGTELNVADFKEMIQQVVFAASTDEARPVLQGVNLTVSDHEISMAATDGFRISVRKARLSTPSERPVSAIIPARALSELARIASDTDEKVTMVVPPGRGQVLFHFDDIELVSQLIEGNFPDYKAIIPRSSKTSTIMATAAFQKACKQAEIIAREGNYVVRLNIQNGEEGPGSVEVSAQSEETGNSEVMVDANITGGGLVIAFNVRYLREVLDVIKSPSVALETNANNTPGVIKAVGSEDFTHVIMPMHLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y5I9</accession>
    <name>A0A0P6Y5I9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_01730</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061234.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01730"/>
    <dbReference type="EnsemblBacteria" id="KPL80587">
        <property type="protein sequence ID" value="KPL80587"/>
        <property type="gene ID" value="ADN00_01730"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000572">
        <property type="entry name" value="OxRdtase_Mopterin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036374">
        <property type="entry name" value="OxRdtase_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00174">
        <property type="entry name" value="Oxidored_molyb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56524">
        <property type="entry name" value="SSF56524"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidored_molyb" evidence="2">
        <location>
            <begin position="36"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL80587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="214" mass="24710" checksum="3B33E418E228246F" modified="2016-01-20" version="1">MDGIFRRKEEEKRMGAEGRLPPGQALTNKFPVLHYGTIPTVDLTTWTLRIWGAVEQPFELSWEEFNRLPRTTLHMDIHCVTQWSKFDTTWEGVALRTLIDEGLLRLKPEAKHVLQHADHGYTTNLPLDVMLQDNFLLATHFNGEPITPEHGYPLRGVVGAIPGRADLKTPYFWKGAKWLRGLEFLTQDQLGFWEKAGYHNDADIWKEQRYASQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y6H7</accession>
    <name>A0A0P6Y6H7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_00390</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060974.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00390"/>
    <dbReference type="EnsemblBacteria" id="KPL81035">
        <property type="protein sequence ID" value="KPL81035"/>
        <property type="gene ID" value="ADN00_00390"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002782">
        <property type="entry name" value="Mut7-C_RNAse_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027798">
        <property type="entry name" value="Ub_Mut7C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01927">
        <property type="entry name" value="Mut7-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14451">
        <property type="entry name" value="Ub-Mut7C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="SSF54285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ub-Mut7C" evidence="2">
        <location>
            <begin position="2"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="domain" description="Mut7-C" evidence="1">
        <location>
            <begin position="95"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL81035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="258" mass="30034" checksum="47663FFAD44C1A2D" modified="2016-01-20" version="1">MKIFLRFYGDLNFFLPASHRQRTYPVEIVARDSIKDLIEAQGIPHTEIDFILVNGNAVGFDTIVAENDRISVYPYFENLPIPIEQRVSEPYPYEPRFVLDVHLGRLAVYLRLLGFNTLYFGNLLDEDLAEISAREGRILLSRDRGLLKRKIVRFGRYIHSTWPHEQLVEVARRYHLLEQSHPFTRCTVCNGSLMEVDMHVVKNEIPAETRANIDRCWRCEECGKVYWKGSHTVRIERMFAEVLTLVSVSSAKSEEMTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y7Q2</accession>
    <name>A0A0P6Y7Q2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Neelaredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_08775</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the desulfoferrodoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000022">
        <property type="protein sequence ID" value="KPL77671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062616.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000022.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08775"/>
    <dbReference type="EnsemblBacteria" id="KPL77671">
        <property type="protein sequence ID" value="KPL77671"/>
        <property type="gene ID" value="ADN00_08775"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1473"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002742">
        <property type="entry name" value="Desulfoferrodoxin_Fe-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036073">
        <property type="entry name" value="Desulfoferrodoxin_Fe-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01880">
        <property type="entry name" value="Desulfoferrodox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49367">
        <property type="entry name" value="SSF49367"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00332">
        <property type="entry name" value="neela_ferrous"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Desulfoferrodox" evidence="6">
        <location>
            <begin position="11"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL77671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="132" mass="14531" checksum="A3437892B20DB171" modified="2016-01-20" version="1">MSGIGERIQQADWKKEKHAPVIHCPDAVVAGQAFEIKVNIGEEIAHPNTTEHHISYITVFFHPEGEKFTYQVGHFEFSGHGEAVAGPNQGPVYTEPSVVAMMKLSKPGTLHAVSFCNIHGLWESEKEIKIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y868</accession>
    <name>A0A0P6Y868_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_08205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062503.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77854">
        <property type="protein sequence ID" value="KPL77854"/>
        <property type="gene ID" value="ADN00_08205"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133446" evidence="1">
        <location>
            <begin position="25"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="228" mass="23925" checksum="54CA8605AEDEE9A0" modified="2016-01-20" version="1">MTAFQKKLALPVLLLMTLSLVSCAAPAVTPEPQPTVDMPALQTEVAATVIADITQQALAQPAADQVEPTATQPVVATATEAPTPTAIATLAPLPTATKRVVSSGGGAPAPTWTPASSTDQAVLVSNRPADYSYFKGGEAFDGVFTIKNVGRRDWNNRFYVTGTDFQGNKVGPILLSGAAVGDTVEIIVDLTAPDYVEGGKNFHTATFNLYNDDGVSILSFYLIINIEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YAY4</accession>
    <name>A0A0P6YAY4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_04175</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061703.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79079">
        <property type="protein sequence ID" value="KPL79079"/>
        <property type="gene ID" value="ADN00_04175"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039562">
        <property type="entry name" value="MFP_biotin_lipoyl_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13533">
        <property type="entry name" value="Biotin_lipoyl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133469" evidence="2">
        <location>
            <begin position="23"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="Biotin_lipoyl_2" evidence="3">
        <location>
            <begin position="61"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="4">
        <location>
            <begin position="273"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="94"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="227"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL79079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="399" mass="42714" checksum="791A35D3411190F0" modified="2016-01-20" version="1">MSPKGAKLFSLSIVLLASLALAACGGAPAAQATPTSDVLPPVTAETFSILAEGQVVPAQSATLSFQTAGVVETILVEEGQSVKAGDPIARLTGSERLRSQLTAAKLELIQAEQALDTLNKTAALARAQAELTLARAQIELQDAKEDREKLKYRRASDNTLDQIRADFILAEDFLDQVEEKFEGVADRAEDDPIRAAALSQLASARKARDRALYNLNYALGLPDPEDVAEAEARLQVAQQSVDDAQRTLDKFVGDGPNTDDLALAEARVANAKAAVAAAEAALADLELTAPFDGTMVANNLKEGEYVTPGVAAAQLGNLSEWKVETTDLTELNVVDIKTGAPVRVTFDAITDLELTGTVERIKPLGENRQGDITYTILIKLDDQDPRLKWNMTAFVTFEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YBV9</accession>
    <name>A0A0P6YBV9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_02615</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000012">
        <property type="protein sequence ID" value="KPL79427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061405.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000012.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02615"/>
    <dbReference type="EnsemblBacteria" id="KPL79427">
        <property type="protein sequence ID" value="KPL79427"/>
        <property type="gene ID" value="ADN00_02615"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="502"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="582"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="584"/>
            <end position="603"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="902" mass="102525" checksum="E06D8DFAEAD69756" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YCP9</accession>
    <name>A0A0P6YCP9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ribose 5-phosphate isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_02180</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LacAB/RpiB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000009">
        <property type="protein sequence ID" value="KPL79792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061324.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000009.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02180"/>
    <dbReference type="EnsemblBacteria" id="KPL79792">
        <property type="protein sequence ID" value="KPL79792"/>
        <property type="gene ID" value="ADN00_02180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016861">
        <property type="term" value="F:intramolecular oxidoreductase activity, interconverting aldoses and ketoses"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004785">
        <property type="entry name" value="RpiB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003500">
        <property type="entry name" value="RpiB_LacA_LacB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036569">
        <property type="entry name" value="RpiB_LacA_LacB_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02502">
        <property type="entry name" value="LacAB_rpiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005384">
        <property type="entry name" value="RpiB_LacA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89623">
        <property type="entry name" value="SSF89623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01120">
        <property type="entry name" value="rpiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00689">
        <property type="entry name" value="rpiB_lacA_lacB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="66"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR005384-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="151" mass="16490" checksum="144A48D7CBB63C93" modified="2016-01-20" version="1">MKVAFACDHAGVLLRDAVVEAIREGGHTLVDFGIYSKEEKADYPDKAEEACRALQDGRAERAVLVCGSGVGVCLSANKMKGIYASVCHDTYTARQGVEHDQMNALCMGGRVIGDELAKDVVKAFLSATHSTQERHLRRVHKIQAIEEQSMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YEQ8</accession>
    <name>A0A0P6YEQ8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ferredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_01335</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061244.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01335"/>
    <dbReference type="EnsemblBacteria" id="KPL80597">
        <property type="protein sequence ID" value="KPL80597"/>
        <property type="gene ID" value="ADN00_01335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010995">
        <property type="entry name" value="DNA_repair_Rad51/TF_NusA_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025567">
        <property type="entry name" value="DUF4332"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14229">
        <property type="entry name" value="DUF4332"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47794">
        <property type="entry name" value="SSF47794"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4332" evidence="3">
        <location>
            <begin position="8"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL80597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="134" mass="14845" checksum="5405CFD25F29876F" modified="2016-01-20" version="1">MAKLEYVEGIGETYADKLRAAGVTTTDKLLEMGSTPKGREEIAQKAGIPEKLILEWVNAVDLFRINGVGQEYADLLEEAGVDTVPELAQRKPENLYAKMVEVNTAKKLVRAMPTEAQVADWVAQAKQLPRIVKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YF78</accession>
    <name>A0A0P6YF78_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Ectoine utilization protein EutC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_01080</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000003">
        <property type="protein sequence ID" value="KPL80816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061116.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01080"/>
    <dbReference type="EnsemblBacteria" id="KPL80816">
        <property type="protein sequence ID" value="KPL80816"/>
        <property type="gene ID" value="ADN00_01080"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1960"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003462">
        <property type="entry name" value="ODC_Mu_crystall"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023401">
        <property type="entry name" value="ODC_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13812">
        <property type="entry name" value="PTHR13812"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02423">
        <property type="entry name" value="OCD_Mu_crystall"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001439">
        <property type="entry name" value="CryM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL80816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="326" mass="34908" checksum="6E885271685C550D" modified="2016-01-20" version="1">MLILNEKEIRQLVPMDIPALQAVAEGFRKLSCGEATLPPIMRIDVPEHNGEVDVKSAYLHGLNAFAIKVAAGFFDNASLGLPTGSGMMLVVSAVTGFPQAVLLDNGYLTDVRTGLAGALAAQYLAPANPQRVGVIGSGMQSRYQIRALKLVREFSQLIVYGIDPLAVQAYAQDMQAELGLSVQIAASPEEVVRQSDFVVTTTPSHQPIVKAEWLHAGLHITCMGADSEHKQEIEALAFGKASRIACDSRAQCLRLGELHHALQTGVIDQQTPITELGEIVAGRLPGRQSPEEITICDLTGVGVQDTQIALLAYHRALSQGVGMKID</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GLB4</accession>
    <name>A0A0N8GLB4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ADN00_16190</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064082.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72026">
        <property type="protein sequence ID" value="KPL72026"/>
        <property type="gene ID" value="ADN00_16190"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3675"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="15"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="50"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="134"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="236"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="279"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="17"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="343"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="379"/>
            <end position="386"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL72026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="589" mass="64545" checksum="9EF454F799CC94E1" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMS7</accession>
    <name>A0A0N8GMS7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_12390</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063328.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12390"/>
    <dbReference type="EnsemblBacteria" id="KPL76130">
        <property type="protein sequence ID" value="KPL76130"/>
        <property type="gene ID" value="ADN00_12390"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="172" mass="19238" checksum="DBE1B26804FEA3E5" modified="2016-01-20" version="1">MINRDYWIGVVLLVVMCLSACSPAETGYSPSGLEGWVTRADIEALANWQTDLKGAQELDGELVSDIQRLQDGSELLVFMNLQSSDSRMMAQRVFLLMDEAGYSQAVRFFNLEKENEKLTNVAAIWKVKEYPTLLVVRNGLEVGRISGTPDEDFENVVVEALREPSPSEFKEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMX7</accession>
    <name>A0A0N8GMX7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_11220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063105.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76530">
        <property type="protein sequence ID" value="KPL76530"/>
        <property type="gene ID" value="ADN00_11220"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.940"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="16"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="327" mass="36957" checksum="180507A4AC38DF8F" modified="2016-01-20" version="1">MQYRTFGRTGWQVSTISFGAWAIGGDWGSVSDEESLATLHSALDQGINLFDTADVYGDGRSERLMARLRKERSEPFHIITKAGRRLNPHVASGYNRQNLTAFVERSLKNLNTDCLELVQLHCPPTEVYYTPEVFEVLDDLVRQGKIQYYGVSVEKVEEALKAIEYPQVQSVQIIYNIFRQRPAELFFREAQRRQVAILARVPLASGLLTGKFTPQSSFESSDHRNYNRHGESFDRGETFSGVDYETGLAAVEALRPLVPQGASMAQFALRWILMDQAVTCAIPGAKRPSQVEQNAAAADLPELPAETMQTIRAIYDQYIRAQVHHRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNB6</accession>
    <name>A0A0N8GNB6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_08565</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000022">
        <property type="protein sequence ID" value="KPL77642.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062579.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000022.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77642">
        <property type="protein sequence ID" value="KPL77642"/>
        <property type="gene ID" value="ADN00_08565"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77642.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="63" mass="7268" checksum="55E169A4D6D25900" modified="2016-01-20" version="1">MQAADILRLLLVVFSFAMLFLSFFYLFRRKLTFWDYLGWGLVAVLIPILGPFLVIASRPGKSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNK0</accession>
    <name>A0A0N8GNK0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_07630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062384.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07630"/>
    <dbReference type="EnsemblBacteria" id="KPL78314">
        <property type="protein sequence ID" value="KPL78314"/>
        <property type="gene ID" value="ADN00_07630"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013105">
        <property type="entry name" value="TPR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07719">
        <property type="entry name" value="TPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="58"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="250"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="288"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="446" mass="50113" checksum="C3D5CCB521D6F49D" modified="2016-01-20" version="1">MNRPLSRPLFHKQRARSEPYRVLVLLLLLVAGLFVLRAVDQDQIRSPFDPTPVPTRTGFSWATEAQTQFQAGNLVMAINAYQSALELEPNNAEMWAELSRIQSYRSTQLTTDAEKREQLLAAIESADRAIAADDFNSNAHAARAFALDWFSNPNLSGADSERYLTEAEQEAVRAIQLDNRNALALAYYAEILNDQMKWTQASQYIVQALERDSTLMDVHRVNAGIQETLANYGEAINEYKRATEITPNLTFLYLNIGVNYRQLQQYERALEYFAKAANINEQLGVNDPTPYIAIGKTYSQVGEFFIAARNVRKALQLNPTNPDVYGSLGIIYFKSRNYEGAIEALKCAVRGCDAQETCNVRMGSVCEESEVDPQFTIEGMPLSGSTVVYYYTYGSALAGMARPYNDYCVEARALMNEVRAQFSGEPVVMQIVEENEAVCDQFVTYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNP4</accession>
    <name>A0A0N8GNP4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Iron transporter FeoB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061925.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05260"/>
    <dbReference type="EnsemblBacteria" id="KPL78666">
        <property type="protein sequence ID" value="KPL78666"/>
        <property type="gene ID" value="ADN00_05260"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1526"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01879">
        <property type="entry name" value="FeoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030389">
        <property type="entry name" value="G_FEOB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02421">
        <property type="entry name" value="FeoB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51711">
        <property type="entry name" value="G_FEOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FeoB-type G" evidence="1">
        <location>
            <begin position="4"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="170" mass="18503" checksum="ADDE8AD147A247EC" modified="2016-01-20" version="1">MENQITIALAGNPNAGKSTIFNALTGSRQHVGNWPGKTVEKKEGLWNHNGNSFTVVDLPGTYSLTAFSLEEVIARDFIIHQKPDLVVAIVDAANLERNLYLVVQVIELGAKVVMVLNMSDVAESRGIKIDSRKLADRLRIPVVQTVASREKGIDELKTTIAEIVTRGGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNP5</accession>
    <name>A0A0N8GNP5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_05320</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061936.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05320"/>
    <dbReference type="EnsemblBacteria" id="KPL78674">
        <property type="protein sequence ID" value="KPL78674"/>
        <property type="gene ID" value="ADN00_05320"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="6"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="146"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL78674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="217" mass="24048" checksum="71D69592294F8B63" modified="2016-01-20" version="1">MNEKIHLLIADDHRVVREGLKAFIAPTPGFEIVGEASNGAEAVDLASRLKPDVILLDLMMPGMDGIEATQQIRQNNPNARVVIITSFMEEDRVIHAVKAGAAGYLLKDSSPLEIENAIREVVKGGSAFPSRIASILVKEINRPQEKPKDKIPLTEREIEILKLIARGYSNQQIADELFLSVWTVRTYVSTVLEKLAVENRTLATLYALREGLVKLEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNP8</accession>
    <name>A0A0N8GNP8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PfkB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05475</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78698.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061966.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05475"/>
    <dbReference type="EnsemblBacteria" id="KPL78698">
        <property type="protein sequence ID" value="KPL78698"/>
        <property type="gene ID" value="ADN00_05475"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PfkB" evidence="1">
        <location>
            <begin position="24"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78698.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="305" mass="33140" checksum="90C94ECAD8DA5730" modified="2016-01-20" version="1">MIDYLAFTLILDDIAMPDGTLQSSVLGGGGPQTAFGMSLFSQHVGIVSGVGRDLPGEARDWFAAHQIDTQGLAASDWPTLRALQVMSRNGNRQQVWRSAGEAIARQLGWRLEDLPEAYRRARGWHLGIHPDQFDFERLWAIKAAPGRVLSVEAFRPAGRPVSPAELQGLLNCVDIFSVNLQEAYSLVGEGTPEKLCERFMRLGKALFVLRIGDQGSWAANPGTGEIVHAPAVKAPVRHEVGAGNAYCGGFLTGWVEENNLREACARGAVAASFWIEGGPRWTAAPPRTVLESRLEEVKARMVTVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNU7</accession>
    <name>A0A0N8GNU7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_04265</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04265"/>
    <dbReference type="EnsemblBacteria" id="KPL79090">
        <property type="protein sequence ID" value="KPL79090"/>
        <property type="gene ID" value="ADN00_04265"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042106">
        <property type="entry name" value="Nuo/plastoQ_OxRdtase_6_NuoJ"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="142" mass="15150" checksum="CD4570C8028C5C95" modified="2016-01-20" version="1">MLLSAIWLAGASALTALMLYMLGAPEVAVIELSVGAGLVTVLFVFAINISGEELQLNHHSIPQTLVWAVLFIVVTLAGLLSLPALNTPFSGPDQATHLQTTLWEDRSLDMLLQILLIFAGVLGVLSLLSGQENKFPKGKDSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNW6</accession>
    <name>A0A0N8GNW6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">FAD-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_04535</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061768.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04535"/>
    <dbReference type="EnsemblBacteria" id="KPL79242">
        <property type="protein sequence ID" value="KPL79242"/>
        <property type="gene ID" value="ADN00_04535"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.265"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007419">
        <property type="entry name" value="BFD-like_2Fe2S-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041854">
        <property type="entry name" value="BFD-like_2Fe2S-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04324">
        <property type="entry name" value="Fer2_BFD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="1">
        <location>
            <begin position="10"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="domain" description="Fer2_BFD" evidence="2">
        <location>
            <begin position="416"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="498" mass="54654" checksum="8B7CFAB41FA5D718" modified="2016-01-20" version="1">MEGTVQKEFDVIIIGGGVVGTMVARWLSRYQWDVLLIEKQADVAMGTTAANTAIVHAGYDPVPGSLKAKMNVLGNKMFDQLAGELNFAFDRRGDYVVAVGDDELPALEVLMEQGKKNGVPGMILLPGAEVRRREKNINPNVSGALWASTGGVCDPFQITVAAAENAIMNGVTVMVETEFQDFIFDGKRIVGMKTNRGDFKCKWAINCAGLYSDVVMHKAGIRPDFKIKPRRGEYFVLDRAEITIDNVIFPTPSDKGKGIMVTTTVHGNTIIGPNAVVHEDKEDKSVTTEGMDEIWEGAMKLVPGLKKSHVIATFAGNRAYGNGPSRDPSLNYNHDFIIEIPEEVQGFVNLGGIESPGLVSSPAIALEVVELLKDAKALPPEKREWEPVRMARPRFRDLSNQDRQLLVERDPAYGRVICRCENVTEGEILAEIHAPLPARTYDAIKRRTWCGTGRCQAGFDTPRVVQLLAQELGVSPLEITKKGPGSEFLFRTTKDVEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GPG3</accession>
    <name>A0A0N8GPG3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Amino acid ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_01090</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000003">
        <property type="protein sequence ID" value="KPL80818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061118.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01090"/>
    <dbReference type="EnsemblBacteria" id="KPL80818">
        <property type="protein sequence ID" value="KPL80818"/>
        <property type="gene ID" value="ADN00_01090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010065">
        <property type="entry name" value="AA_ABC_transptr_permease_3TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043429">
        <property type="entry name" value="ArtM/GltK/GlnP/TcyL/YhdX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30614">
        <property type="entry name" value="PTHR30614"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01726">
        <property type="entry name" value="HEQRo_perm_3TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="55"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="186"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="7">
        <location>
            <begin position="19"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL80818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="223" mass="24375" checksum="00A8FA607A101A68" modified="2016-01-20" version="1">MNEFLEFFQSALPSFYRGALITLQLTAVGLGLGFLLGLPAAVLRVYGGKYLRWLAIAYIELFRGTPVLVQLFLVYFGLPDLGMTLSRMTAAYIVLGLNSGAYQAEYFRGAIQAVGGGQMMAARAIGMSRLEAIRHIILPQALRLVIPAWSNEPPSLLKASAIAFLIAVPDLMTQAKTIAAHTYNPIGAYFSVAVIYLVIVFAMNSLSSYMERKARVPGLELEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GPI9</accession>
    <name>A0A0N8GPI9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CBM20 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_00325</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060962.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL81026">
        <property type="protein sequence ID" value="KPL81026"/>
        <property type="gene ID" value="ADN00_00325"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001070">
        <property type="term" value="F:starch binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013784">
        <property type="entry name" value="Carb-bd-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002044">
        <property type="entry name" value="CBM_fam20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49452">
        <property type="entry name" value="SSF49452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51166">
        <property type="entry name" value="CBM20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBM20" evidence="1">
        <location>
            <begin position="242"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL81026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="808" mass="88229" checksum="BD25937D96CA373B" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WMR4</accession>
    <name>A0A0P6WMR4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Nicotinate phosphoribosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_17640</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000042">
        <property type="protein sequence ID" value="KPL71222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064371.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000042.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17640"/>
    <dbReference type="EnsemblBacteria" id="KPL71222">
        <property type="protein sequence ID" value="KPL71222"/>
        <property type="gene ID" value="ADN00_17640"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2792"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004514">
        <property type="term" value="F:nicotinate-nucleotide diphosphorylase (carboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036068">
        <property type="entry name" value="Nicotinate_pribotase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037128">
        <property type="entry name" value="Quinolinate_PRibosylTase_N_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51690">
        <property type="entry name" value="SSF51690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL71222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="447" mass="50491" checksum="83B0434F2F5797AD" modified="2016-01-20" version="1">MSVFDNKRLDNSTFKLDIDRMRDGWYTDKYFVNIANMLTVLAKENYIYNGQYPNLPSSMVEKGINCGDIEVEMQFFTRRLGDTVVVGIDKALTMLRHCTGYWQEDQWVDTHANLEVWAVQDGCTVHSNGDPMDVQPVMRVRGHYRDFAHLETTLLGILARASRVATNVYQTLIAARGKPLLFFPARFDVHEVQAADGYAYHIAVERYNMDYAHKLGPFVSTDAQGDWWGGAGGGTVAHAAIASFLGDTAEAMLAFARIQPASIVRIALVDFNNDCVTDSLRVCTAMFQKYRELVDKGEMDEAERYRLYGVRLDTSASLRDVSVPPLGDPKLDLGVTPRLVHIVREALDNAWKDWNLPAEWVERAQEFCSFVKIVVSGGFDAERIDRFERLGVPVDIYAVGSSLFDNHGPTKADYTADVVRVKIHGEWVDMAKIGRRPCENPDLERIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WQC1</accession>
    <name>A0A0P6WQC1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_15675</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15675"/>
    <dbReference type="EnsemblBacteria" id="KPL72255">
        <property type="protein sequence ID" value="KPL72255"/>
        <property type="gene ID" value="ADN00_15675"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029432">
        <property type="entry name" value="Sipho_Gp37"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14594">
        <property type="entry name" value="Sipho_Gp37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="377" mass="41970" checksum="E428C6ADE58AA90E" modified="2016-01-20" version="1">MSAEYRIYSRNPDLTRNSEITRYKRLEFISRFCLGGSWTLSGEGDLPLSVNQGIIIVRNDVEVFSGVVQELETAMDAESFLSRSWTFKGKDDLARIGDRVAVPDPVGWNFSTAAYDTRTGLAEAVILEFVDYNCGPSAIERRRLPNFQVGASSGLGLTVTGNARFDNLLTLIYNLAQMGGVGYRVRYDSTLGRLVFEVFEPTDRTTEVKFSADFGNLQSFKHKLRAPKANYAIVLGQGEGSSRSNVCVYDNNSISTWGLVEMMKDQRNEPDSAKLQNWGEAELEKKKEQEGYTIVPNELGGVGFTYGVDYFLGDLVSVADEAVVLQETVTEVKFSIDEDGEEKIVPTIGSLKDIPLSNTFERIEDLTDRVNQIETSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WR60</accession>
    <name>A0A0P6WR60_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">2-ketoisovalerate ferredoxin oxidoreductase</fullName>
            <ecNumber evidence="3">1.2.7.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_16850</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.7.7" evidence="3"/>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064219.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16850"/>
    <dbReference type="EnsemblBacteria" id="KPL71374">
        <property type="protein sequence ID" value="KPL71374"/>
        <property type="gene ID" value="ADN00_16850"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.430"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043807">
        <property type="term" value="F:3-methyl-2-oxobutanoate dehydrogenase (ferredoxin) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd07034">
        <property type="entry name" value="TPP_PYR_PFOR_IOR-alpha_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033412">
        <property type="entry name" value="PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002880">
        <property type="entry name" value="Pyrv_Fd/Flavodoxin_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17147">
        <property type="entry name" value="PFOR_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01855">
        <property type="entry name" value="POR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="POR_N" evidence="1">
        <location>
            <begin position="14"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="PFOR_II" evidence="2">
        <location>
            <begin position="246"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL71374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="368" mass="40314" checksum="B44F998CF88EC258" modified="2016-01-20" version="1">MAKELLKGNVAFAEAAIRAGLQAYFGYPITPQTEALEWMSQRMPELGRAFVQAESELGAINMVYGAACTGARVMTSSSSPGISLMMEGISYIAGTEVPAVIVDVARGGPGLGNIAPAQGDYNQIVHGGGHGDYYPIVLAPANVQELIDQTALAFDLAEKYRSVVFILIDGVLGQMMEPAELPPMRPVRQTVPDWAVHGVPGRGKHILNSLYINPPDQEEVDIRLLKRWMEIKANEVRYKTYFTEDAEYLLVGFGTSGRVALSAVRAARAKGIKVGLMRPITLAPYPEKELEELSQRMKGILVVEMNNGQMLDDVLRITKGRVPVEFYGRPGGIVPLPDEVLADIERLTSSQFSLDGDPRERWLARMQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WRD8</accession>
    <name>A0A0P6WRD8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">DNA alkylation repair protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_16715</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16715"/>
    <dbReference type="EnsemblBacteria" id="KPL71484">
        <property type="protein sequence ID" value="KPL71484"/>
        <property type="gene ID" value="ADN00_16715"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.401"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014825">
        <property type="entry name" value="DNA_alkylation"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08713">
        <property type="entry name" value="DNA_alkylation"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL71484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="205" mass="23412" checksum="1866C2F41AAF0EF4" modified="2016-01-20" version="1">MANPAFAQQHERFGSFAAQKLGIRVPDLRALAKGNRSHTLAQQLWQTGIHEARILATMVDDPKQVTRQQMDAWIQDFDAWDICDQACCNLFEPTPFALDCALEWPHLKPEYQRRAGFALIAYLAIHRKKLPDETFAPYLALIEQYASDERNFVKKAVNWALRQIGKRSPALCQRAIQTAERIARQDSPAARWVAADALRELRARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WST5</accession>
    <name>A0A0P6WST5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Na_H_Exchanger domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_18145</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL69992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064461.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18145"/>
    <dbReference type="EnsemblBacteria" id="KPL69992">
        <property type="protein sequence ID" value="KPL69992"/>
        <property type="gene ID" value="ADN00_18145"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015299">
        <property type="term" value="F:solute:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006812">
        <property type="term" value="P:cation transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="55"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="86"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="115"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="151"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="186"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="226"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="250"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="278"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="306"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="336"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="360"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="Na_H_Exchanger" evidence="5">
        <location>
            <begin position="9"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL69992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="416" mass="45361" checksum="D23F422958A592DD" modified="2016-01-20" version="1">MEIFLLFTVLALVVITFGYFINKYLKMPWMFTAVLFGMILSSFGLFTDVMKSQEFLFLSKIGMFFFLFTIGLDLDLSQIRKLGGYIIAGNVLLTLTEGLLIASLLYFVFPVFVSHSILVALLCGIAFGTVGEVILLAILKEFGLEKTRFGQLALGIGVFDDIFEILVLSIIIALPAFSVSASQGEAWNRAIGIVISLAAIIGATILLSKVGKLVQKQVMKVQGNSFVLPFMIFMVFFAFLYFGTLGFENLGVVAAIFAGISVNHLFPEKVVEQYKKPIFFVGNMFLGPFFFLSIGGSMSFSALLSYPLLILAIMAISVLARTLVSYLLFRKLLGSRLSVVMGIGLTAKFSTSVISENLLFTSGMIAQPLYSALMAAFILLKPIIIGGFSKGLAITKEAHTEFRGASSEAIPAAFKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WT29</accession>
    <name>A0A0P6WT29_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_15660</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063969.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72252">
        <property type="protein sequence ID" value="KPL72252"/>
        <property type="gene ID" value="ADN00_15660"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="97" mass="10952" checksum="C2426B987F277767" modified="2016-01-20" version="1">MNYLEIYNEIYSNANIEKKVVVACLQSADTIIREDVSTENHDLRMSWARSVISNPIQAARKMLPVIIVNPIVQSGAYDDGDLLWLVQTNINAYALIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WX23</accession>
    <name>A0A0P6WX23_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_13365</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063521.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000031.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13365"/>
    <dbReference type="EnsemblBacteria" id="KPL74824">
        <property type="protein sequence ID" value="KPL74824"/>
        <property type="gene ID" value="ADN00_13365"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1157"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025584">
        <property type="entry name" value="Cthe_2159"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14262">
        <property type="entry name" value="Cthe_2159"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132689" evidence="2">
        <location>
            <begin position="26"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="413"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL74824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="640" mass="65292" checksum="FA830A6FF8DE74E8" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WXZ8</accession>
    <name>A0A0P6WXZ8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7 8">Transcription elongation factor GreA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Transcript cleavage factor GreA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">greA</name>
        <name evidence="11" type="ORF">ADN00_16990</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7 8">Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the GreA/GreB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064245.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16990"/>
    <dbReference type="EnsemblBacteria" id="KPL71395">
        <property type="protein sequence ID" value="KPL71395"/>
        <property type="gene ID" value="ADN00_16990"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.458"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070063">
        <property type="term" value="F:RNA polymerase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032784">
        <property type="term" value="P:regulation of DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00105">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036953">
        <property type="entry name" value="GreA/GreB_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018151">
        <property type="entry name" value="TF_GreA/GreB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006359">
        <property type="entry name" value="Tscrpt_elong_fac_GreA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028624">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001437">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023459">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022691">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036805">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30437">
        <property type="entry name" value="PTHR30437"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01272">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03449">
        <property type="entry name" value="GreA_GreB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006092">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46557">
        <property type="entry name" value="SSF46557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01462">
        <property type="entry name" value="greA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00830">
        <property type="entry name" value="GREAB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4 7 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="11" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 7 8" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="GreA_GreB_N" evidence="10">
        <location>
            <begin position="6"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="GreA_GreB" evidence="9">
        <location>
            <begin position="82"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="11"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL71395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="155" mass="16999" checksum="9BD23A82A05E1173" modified="2016-01-20" version="1">MTTSFLTREGFEALQKELDFLRDERREEIAERLHEAIIEGGELIENAEYEAAKNEQAFVEGRIKELEILLATARIVDEGVKQTGVIQVGTRVTIQEEDGEPEEYVIVGAAEANPSQGKVSNESPLGKALVNRRAGDTVTVNAPAGSFTVTILKVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WY40</accession>
    <name>A0A0P6WY40_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_17405</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064321.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL71459">
        <property type="protein sequence ID" value="KPL71459"/>
        <property type="gene ID" value="ADN00_17405"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035168">
        <property type="entry name" value="DUF5317"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17248">
        <property type="entry name" value="DUF5317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL71459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="195" mass="21758" checksum="561434E9E280D64B" modified="2016-01-20" version="1">MILLTAVVAGLIAGFIRAKVNGRRLRSIVLRLEWLAFIAFLPHIIAFELPFTRSSIPDDWARLALITSQALLLVFALFNLNEAGLAVMALGLALNLFVILLNGGLMPISPEVLDRFFPGGAGQIWQIGERVLTSKDIVLTKDQTVLWLLSDRLTLPEWIPYHVAFSIGDIFIWIGAFFLLWSLGGKSRDIFQEIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WY81</accession>
    <name>A0A0P6WY81_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BPL/LPL catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_16905</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064228.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16905"/>
    <dbReference type="EnsemblBacteria" id="KPL71382">
        <property type="protein sequence ID" value="KPL71382"/>
        <property type="gene ID" value="ADN00_16905"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004077">
        <property type="term" value="F:biotin-[acetyl-CoA-carboxylase] ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16442">
        <property type="entry name" value="BPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004408">
        <property type="entry name" value="Biotin_CoA_COase_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03099">
        <property type="entry name" value="BPL_LplA_LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00121">
        <property type="entry name" value="birA_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="1">
        <location>
            <begin position="12"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL71382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="259" mass="28229" checksum="1C67D3DCA79D33FE" modified="2016-01-20" version="1">MNEVDLTKALKRLEIPSFQFFEKIGSSNDAALTWAASGAPDGALVIADEQTQGRGRMNRQWVTVPGAALAFSLIFRPSPQEQEGISLFSALAGVAVQQALEKTFGLPAEIKWPNDVLVNGKKLCGVLVESVWMEARVEAVVVGIGVNVAPSSVPAPEMLLFPATCVETEADRPADRLLLLREILREITAWRKHLLSSVFYQLYSSRLAFQGQWVKVSQPGDQITYGRLKGVRTNGCLLLESEAGDEIALTIGDVHLRLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZG5</accession>
    <name>A0A0P6WZG5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Type II secretion system protein E</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_15255</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP E family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063899.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15255"/>
    <dbReference type="EnsemblBacteria" id="KPL72187">
        <property type="protein sequence ID" value="KPL72187"/>
        <property type="gene ID" value="ADN00_15255"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.753"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00662">
        <property type="entry name" value="T2SP_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SP_E" evidence="3">
        <location>
            <begin position="309"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL72187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="464" mass="51435" checksum="1B3BC8D38AE1BFA9" modified="2016-01-20" version="1">MSILKRLQGTEGTPTPVPVGKDTRPNSAVQARRITAPTTSSVQDTYLDLKTRVQNKLLAGLDPSTDVTKVNEVRHTILELFEQILAEENIVLSRPERARLFEQIAAEILGFGPIQPLLEDEQITEIMVNGAKNIYIERRGKIHRVPVSFESQDHVLRIIDRIVAPLGRRIDESSPYVDARLPDGSRVNAVIPPISLVGPVITIRKFSKNPITIEQLIKFESITPEAMKFLKACVESRLNVVISGGTGSGKTTLLNILSGFIPSDERIITVENAAELQLRQEHVVTLESRPPNIEGRGEITIRQLVINTLRMRPDRIIVGEIRDEAAVDMLQAMNTGHDGSMTTLHSNGPRDTLARLETMVLMAGMDLPVRAIREQISSAVDVIVHQSRMRDGSRKVTYITEVSGMEGDVITLTDIFAFEQTGYDNGKVMGRLRPTGLRPKFMEKIEAAGISLPPTIFGAGERRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZH9</accession>
    <name>A0A0P6WZH9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_15375</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15375"/>
    <dbReference type="EnsemblBacteria" id="KPL72205">
        <property type="protein sequence ID" value="KPL72205"/>
        <property type="gene ID" value="ADN00_15375"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003737">
        <property type="entry name" value="GlcNAc_PI_deacetylase-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024078">
        <property type="entry name" value="LmbE-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12993">
        <property type="entry name" value="PTHR12993"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02585">
        <property type="entry name" value="PIG-L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102588">
        <property type="entry name" value="SSF102588"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="214" mass="24409" checksum="9FAE4C5D04DFB97D" modified="2016-01-20" version="1">MNFYGRRLLFIGAHPDDIELGAGALIAHVAGQTEILCVTLSDNQKNPALSHLVEEYHRSMDVLGVPKEGRILGPFETRRFPDARQEILEYFLKINRDFRPEIVFVHTKADLHQDHGTITEEALRAFRGTTVLGFDVLRSSYGFFPNFLVEVTEQDVEKKIEALSQYSTYKDKYYFSPEITRSTLIRNGALAERHYAEGFEALRIVGSFLNSLHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X261</accession>
    <name>A0A0P6X261_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_14745</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000035">
        <property type="protein sequence ID" value="KPL73595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL73595">
        <property type="protein sequence ID" value="KPL73595"/>
        <property type="gene ID" value="ADN00_14745"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132781" evidence="2">
        <location>
            <begin position="20"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="223"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL73595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="298" mass="33688" checksum="2AA41858F4D24B09" modified="2016-01-20" version="1">MALLCALLLTGLLAGEARAQQPAVRLSQLQIDLWPEYDLPGMLVIYRMTLSPDTLLPAEMSLRIPRAVGKPHKVAQQSMDELLYDLDYTLDTSDEWLTIHFTALSQQVRVEYYDPRLDRIDSERRFVYQWPADFEIGQLVFNIQQPEGASRFDIQPEQGVGKEGEDGMIYYTIEKQNVKAGTVLALEIQYEKTSEQLSHVLQPVRPVEPIAEARIGWSTFMELLPLAVLVFVALVISGSVLWYWQGGGRPRSPLRLPYKRSAARAVLTGVYCRECGKRAMAGDTYCRSCGVKLNDSSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X2P7</accession>
    <name>A0A0P6X2P7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_13080</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000029">
        <property type="protein sequence ID" value="KPL75287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063469.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000029.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13080"/>
    <dbReference type="EnsemblBacteria" id="KPL75287">
        <property type="protein sequence ID" value="KPL75287"/>
        <property type="gene ID" value="ADN00_13080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011579">
        <property type="entry name" value="ATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004256">
        <property type="entry name" value="DUF234_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005471">
        <property type="entry name" value="Tscrpt_reg_IclR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01637">
        <property type="entry name" value="ATPase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03008">
        <property type="entry name" value="DUF234"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09339">
        <property type="entry name" value="HTH_IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase_2" evidence="1">
        <location>
            <begin position="2"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="HTH iclR-type" evidence="3">
        <location>
            <begin position="246"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="DUF234" evidence="2">
        <location>
            <begin position="317"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL75287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="481" mass="54438" checksum="22191E5B28A1F432" modified="2016-01-20" version="1">MFVDRRQEMDFLNSLLTRKRPGPAQLALMFGRRRVGKSELLLQWAAQSGIPFTYWEAVKETATQQRTRFFGKLLNVPASSAPVYRSWPELWDAAAPLLIGKRQILILDEVPYAAEADPAMLSALQYAWDQHFQKSEVVLVLCGSQVRVMEKLFSEQSPLFGRLTGQWHLEPLPFSALAEFFPKWDADARVATYAMVGGIPAYLNWFDPDLDLISNIRQTILSPGSMFLAEPAFLLYDEVREPNSYLSILKAIGSGAHTLTEIGERAYIPSTSVTFYLNTLQELRLVERRLPVTQPKAERGRSRSGRYRLSDPYFRFYFQFLEPFLSSSPHNTEQIIEAVRRNLRAFVGVSAFEELAREWTQMQGKAGKLPFVPDAVGSHWSSRVQVDVVAINWKTHGILLGECKWGTDRVDRQVVRELIETKTPLVIKDLPSEGAGWQVYYAFFARSGFTPAAIEMLQKVGGFAVDLNDLDAVLGHGDSHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X2R2</accession>
    <name>A0A0P6X2R2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_10465</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062947.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76991">
        <property type="protein sequence ID" value="KPL76991"/>
        <property type="gene ID" value="ADN00_10465"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132795" evidence="2">
        <location>
            <begin position="29"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL76991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="194" mass="22054" checksum="1D68F25A5D759381" modified="2016-01-20" version="1">MRPRRGLRWSLWLAAVLLLAACRPSAPAAPTPPGGEENTPTPAETTLPTPLPPFNMAGVSVDVYPEEDDQASYLAVYLNLYNDFFSYFGIAQNEGAEWVNNPLEVALRFQEWPPAEPNCSSRKVYYLPGEDSRQVTIILVLSGCPDETISEMKLRVELQQVESYWNIKWAGKMWKCSRSEYAEYRDNWNLFPCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X372</accession>
    <name>A0A0P6X372_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_09165</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062694.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09165"/>
    <dbReference type="EnsemblBacteria" id="KPL77293">
        <property type="protein sequence ID" value="KPL77293"/>
        <property type="gene ID" value="ADN00_09165"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="271"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="314"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="375"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="19"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="297"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL77293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="409" mass="44602" checksum="EAAD95927BD3764E" modified="2016-01-20" version="1">MNLYLRLAWRNVWRHRRRTLIIMLAIGLGMSMMMMYDGLVAGFEQAIYGNAVQVLGGNIQIHAEGYREKTGQSPLLPLVNDQELIIAAEAQPEVVMASRRIKTTGMATSTEGAFGVSIIGIEPDKEESISLEARNVVDGRYLTAGDTDQIFIGKGLADTMDIVVGDRITVVGKDINKQMRKRTMTVVGIYDINMPDVEKQSIYISLAEAQDLYGLTGQSTEIAIMLEKIGQENAVIRALEPVLGSGEIETWATTFPELRQALETKGAVMDVFSVIILIIAGIGILNMLLMAIFERTREIGVLGALGMKPRQISTLFLLEGCMMGLLGLLSGVLLGVAFNAVLMTVGFDYSAFAGVTEYTALISGKVYSTLGLEKIVQRSLTVIIISILCSFYPAHEASQSEPAHALHYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X3X7</accession>
    <name>A0A0P6X3X7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_14040</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063657.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000033.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74119">
        <property type="protein sequence ID" value="KPL74119"/>
        <property type="gene ID" value="ADN00_14040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL74119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="87" mass="10366" checksum="B2B1C7D3301DA005" modified="2016-01-20" version="1">MPVKNTPEEREIIKLIPKLPVQDSDKNQWMQQIDEFGLTEELVEEIREKLNHPEAGQEDQAGRYRMQLARLVQRWRLASQSRHFSSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X4L4</accession>
    <name>A0A0P6X4L4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_13495</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063547.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000031.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74847">
        <property type="protein sequence ID" value="KPL74847"/>
        <property type="gene ID" value="ADN00_13495"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="231"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="272"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="315"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="339"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="2">
        <location>
            <begin position="6"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL74847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="360" mass="40116" checksum="16FC36409970FDFE" modified="2016-01-20" version="1">MINPELLIRPIRDGEKAEAQRVMRRAFSPPTWLFQTWSKDVLVAEHAGRIVGGVVLKVFTASKRKVGFVSWLFTDPEARGLGAGQALIEGALAFFEAQGCTEFSACVEGYNTSSSKVFSTRGFTILSLGEQLRRYGFGILPYWWHSFHFIDVGHFLWVKPGEEQPDSPLLQWLGTWLINALLLLVAVWRVGTLSVNDLWTIPTAILALFGLRSLAMWGAAKAQGFAVRFRAWESSTTLVAIIALLFGGFFPFPGSFYPVGNEWRYRDVLPKIGPMALAGTLATLVVAWGSWAALRWNLAPGLGPVLFPLQQLSRMLAILESIVAFFPLISYNGRRLWDWNRVIWALVSLAAVALVFLARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X530</accession>
    <name>A0A0P6X530_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062898.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10200"/>
    <dbReference type="EnsemblBacteria" id="KPL76951">
        <property type="protein sequence ID" value="KPL76951"/>
        <property type="gene ID" value="ADN00_10200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06588">
        <property type="entry name" value="PhnB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028973">
        <property type="entry name" value="PhnB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06983">
        <property type="entry name" value="3-dmu-9_3-mt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3-dmu-9_3-mt" evidence="1">
        <location>
            <begin position="7"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="143" mass="15833" checksum="C0590EC48829A6D1" modified="2016-01-20" version="1">MTRASLYLNFAGSSEEALTFYRSVLGGEFLGIMRFRDMPGAPEMSAADAEKVMHMTLPVGDNLMLHASDTLESRGQKLAVGNNFSIMLEPESKAEADRLFSQLSAGGVVEMPMQDMFWGDYYGAFTDRFGVQWMINFANPHSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5K1</accession>
    <name>A0A0P6X5K1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ala-tRNA(Pro) hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_07750</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062407.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07750"/>
    <dbReference type="EnsemblBacteria" id="KPL78335">
        <property type="protein sequence ID" value="KPL78335"/>
        <property type="gene ID" value="ADN00_07750"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3382"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004813">
        <property type="term" value="F:alanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006419">
        <property type="term" value="P:alanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018165">
        <property type="entry name" value="Ala-tRNA-synth_IIc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018164">
        <property type="entry name" value="Ala-tRNA-synth_IIc_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01411">
        <property type="entry name" value="tRNA-synt_2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="SSF55186"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50860">
        <property type="entry name" value="AA_TRNA_LIGASE_II_ALA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II_ALA" evidence="3">
        <location>
            <begin position="1"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL78335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="240" mass="27018" checksum="B4A6EFAF22AEB31B" modified="2016-01-20" version="1">MTELAYQLDSYLQSIEARVAALDTETHAVQLDRTVIYPGGGGQPHDTGLLETPSQTYPVIKAKKIGGEAWHYLSPETPLPAVGNAVTVRVDWPRRYQLMRTHTAMHILCGVIYRDFGAHVTGGDMDPLKGRMDFEFENLSRDLISVIEEAVNREVEAARDVRVRILPREEAFQIPDLIRTKINLLPPEIAEIRTVELVGLDLQADGGTHVANTREVGRMRIVDYKSKGKINKRIYVEMED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-08-12" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X6V7</accession>
    <name>A0A0P6X6V7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_06075</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062075.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78792">
        <property type="protein sequence ID" value="KPL78792"/>
        <property type="gene ID" value="ADN00_06075"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="132" mass="13695" checksum="6AD43E131AF512EF" modified="2016-01-20" version="1">MKTSVQAPLFNGLILPIILGLLIAVIAYANLNNRSLPLINSPRAALIAILIIGMTMCALGGIGQVGASGKWASPFAIAGYLLGAGLLVVLIGGLAGWHLPLIATQKDAVSAASLLILVKFIIGTLSYFFHFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X761</accession>
    <name>A0A0P6X761_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">30S ribosomal protein S13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsM</name>
        <name evidence="8" type="ORF">ADN00_12485</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Located at the top of the head of the 30S subunit, it contacts several helices of the 16S rRNA. In the 70S ribosome it contacts the 23S rRNA (bridge B1a) and protein L5 of the 50S subunit (bridge B1b), connecting the 2 subunits; these bridges are implicated in subunit movement. Contacts the tRNAs in the A and P-sites.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 30S ribosomal subunit. Forms a loose heterodimer with protein S19. Forms two bridges to the 50S subunit in the 70S ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063347.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12485"/>
    <dbReference type="EnsemblBacteria" id="KPL76145">
        <property type="protein sequence ID" value="KPL76145"/>
        <property type="gene ID" value="ADN00_12485"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3978"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.910.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01315">
        <property type="entry name" value="Ribosomal_S13_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027437">
        <property type="entry name" value="30s_Rbsml_prot_S13_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001892">
        <property type="entry name" value="Ribosomal_S13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010979">
        <property type="entry name" value="Ribosomal_S13-like_H2TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019980">
        <property type="entry name" value="Ribosomal_S13_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018269">
        <property type="entry name" value="Ribosomal_S13_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10871:SF1">
        <property type="entry name" value="PTHR10871:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00416">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002134">
        <property type="entry name" value="Ribosomal_S13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46946">
        <property type="entry name" value="SSF46946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03631">
        <property type="entry name" value="uS13_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00646">
        <property type="entry name" value="RIBOSOMAL_S13_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50159">
        <property type="entry name" value="RIBOSOMAL_S13_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5" id="KW-0820">tRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="95"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="107"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL76145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="129" mass="14736" checksum="F33348D78427F48C" modified="2016-01-20" version="1">MARIEGVDLPRNKRIDVALTYIFGIGPTRAKTILEATDVAPEIRVKDLDENQANALREYIAKSYKVEGDLRREVQMNIKRLIEIGCYRGLRHRRNLPLNGQRTRTNARTRKGPKKTVAGRGRRRGAAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X789</accession>
    <name>A0A0P6X789_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Tyr recombinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_18245</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064481.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18245"/>
    <dbReference type="EnsemblBacteria" id="KPL70007">
        <property type="protein sequence ID" value="KPL70007"/>
        <property type="gene ID" value="ADN00_18245"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="2">
        <location>
            <begin position="151"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL70007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="317" mass="35878" checksum="A5EEE4E7B26C32F5" modified="2016-01-20" version="1">MSLSSISNQVNHALAKVTWDKEQIKEFQAEHGVASVKKSLRPGGDPTQPLPVILGINTRRTYFQAATSFFKRAEDITDEGLLVKLLDPDIIMTTFEEHYANAAPGTVNKLMAALEKVHLGCVQLGWTKDACPITPELREWVKSFRDDSDVRMPRFGYRPEDAERVVKYLKDKKSVYALPAELALRCGLREDEIAGLKGENIDQSQQLLHITGKGGRYRQVPIPEDLLDQLNCSKQYLFTPSASWRAGFRRTVRDATRALGIEISGVHRLRANFAQKKYQDCLAQGMDEREARLKVSELLGHARIDVTYKYVPRDFSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7W6</accession>
    <name>A0A0P6X7W6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PEP_hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_12745</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063401.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000027.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL75509">
        <property type="protein sequence ID" value="KPL75509"/>
        <property type="gene ID" value="ADN00_12745"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1244"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009215">
        <property type="entry name" value="TIM-br_IGPS-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09370">
        <property type="entry name" value="PEP_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF034452">
        <property type="entry name" value="TIM-br_sig_trnsd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PEP_hydrolase" evidence="1">
        <location>
            <begin position="8"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL75509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="276" mass="29289" checksum="E0FD2C2CED937FCF" modified="2016-01-20" version="1">MALTRQEMLKRLHAQVAAGKPIVGCGAGTGISAKFAERGGADLIIIYNSGRYRMAGRGSLAGLMPYGDANGIVVEMASEVLPVVKDTPVLAGVCGTDPFRLMPVFLKQLKEIGFSGVQNFPTVGLIDGNFRANLEGTGMGYGKEVEMIRLAHELDMFTSPYVFDEDDAKAMAEAGADQLVAHVGLTTAGSIGAAVAFTLEEAVEKVLKIAEAGRKVRKDILVICHGGPFDEPENVAKALAMMPSIQGFFGASSIERLPTERGIQGQVEAFKSIQLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X8G5</accession>
    <name>A0A0P6X8G5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_06670</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000018">
        <property type="protein sequence ID" value="KPL78405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062202.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000018.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78405">
        <property type="protein sequence ID" value="KPL78405"/>
        <property type="gene ID" value="ADN00_06670"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132906" evidence="2">
        <location>
            <begin position="30"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="258" mass="28337" checksum="FC86FE46B85F2B34" modified="2016-01-20" version="1">MKSLKKANLFLTILIALTMVFAAVQPAFAQEETGPTEITGEVVAIVLPTETEPGSFDVQTETGIVTVFPAEGYDFTLLEVGDMVVVSGTENEDGSLAAEEITIEEPQEPEEPEEPMYPNQGYYCTQSEDMHPMGARLAERYGMDYATLQGWFCEGHGWGQVMLALQTGAAMEMDPALLLEARDAGEGWGNIWKELGLIGKPDKDKDDDDDMEEPEMGADDDDKGKPDFAGPPSNKDKDKDKNNTPNPNSYKDKDKKNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9B1</accession>
    <name>A0A0P6X9B1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_05355</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061943.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05355"/>
    <dbReference type="EnsemblBacteria" id="KPL78679">
        <property type="protein sequence ID" value="KPL78679"/>
        <property type="gene ID" value="ADN00_05355"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1543"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016624">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transket_pyr" evidence="3">
        <location>
            <begin position="472"/>
            <end position="645"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL78679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="819" mass="90346" checksum="36A721094AFFF04E" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9C0</accession>
    <name>A0A0P6X9C0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AAA_31 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061954.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05410"/>
    <dbReference type="EnsemblBacteria" id="KPL78688">
        <property type="protein sequence ID" value="KPL78688"/>
        <property type="gene ID" value="ADN00_05410"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1557"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_31" evidence="1">
        <location>
            <begin position="1"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="256" mass="28283" checksum="EA6DC24BB1FF5041" modified="2016-01-20" version="1">MNIIAFANQKGGVGKTTTAVTLADGLARLGHKTLLVDLDPQGHVAIALGMEKTPGLYRLICLDERLEKVVITARPNLDILGSDKRTEKVKRQITLSDFRESILLDTLQTSSYEFILLDLAPSLDVLHINGLVASDWVIIPTRLDALAVDGVKEILLTMGEVAQRGYSFKGYAILPTFFDRTTRETLTQFQEITRAFGTNVWPPVPQDTRVRESAAFGKTLEEYSASSPAMVGFQDGQRLVGGYRQALHKLLEMTYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9Y7</accession>
    <name>A0A0P6X9Y7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_10675</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062984.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10675"/>
    <dbReference type="EnsemblBacteria" id="KPL77023">
        <property type="protein sequence ID" value="KPL77023"/>
        <property type="gene ID" value="ADN00_10675"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002794">
        <property type="entry name" value="DUF92_TMEM19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13353">
        <property type="entry name" value="PTHR13353"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01940">
        <property type="entry name" value="DUF92"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="86"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="154"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="184"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="246"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL77023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="267" mass="27437" checksum="3CC6C21795A9EEF2" modified="2016-01-20" version="1">MQLFIGFTAAVLISLLAWKTQNLSTSGALAATILGTIVFGLGGLPWAVLLLGFFITSSALSKLLGRRKAALDASFSKGSRRDWAQVLANGGLSGLFVLLHLLQPQATWPWLGFAGTLAAANADTWATELGVLSRAQPYLITSLRPVERGTAGAITLPGTLAALAGGLLIGALAVLVGPMASSSLAVVALIGLAGLLGSLIDSLLAASLQAMYVCPACGKETERHPLHSCGAPTQFKRGWPWLNNDWVNSLCTLAGGAAALLGGLVLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XA51</accession>
    <name>A0A0P6XA51_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phosphoribosyl-AMP cyclohydrolase</fullName>
            <shortName evidence="7">PRA-CH</shortName>
            <ecNumber evidence="7">3.5.4.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">hisI</name>
        <name evidence="9" type="ORF">ADN00_17470</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the hydrolysis of the adenine ring of phosphoribosyl-AMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>1-(5-phospho-beta-D-ribosyl)-5'-AMP + H2O = 1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:20049"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58435"/>
            <dbReference type="ChEBI" id="CHEBI:59457"/>
            <dbReference type="EC" id="3.5.4.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="7">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 3/9.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the PRA-CH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.19" evidence="7"/>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71470.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064333.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17470"/>
    <dbReference type="EnsemblBacteria" id="KPL71470">
        <property type="protein sequence ID" value="KPL71470"/>
        <property type="gene ID" value="ADN00_17470"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.561"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00008"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004635">
        <property type="term" value="F:phosphoribosyl-AMP cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.810">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01021">
        <property type="entry name" value="HisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026660">
        <property type="entry name" value="PRA-CH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002496">
        <property type="entry name" value="PRib_AMP_CycHydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038019">
        <property type="entry name" value="PRib_AMP_CycHydrolase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01502">
        <property type="entry name" value="PRA-CH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141734">
        <property type="entry name" value="SSF141734"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="5 7 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PRA-CH" evidence="8">
        <location>
            <begin position="40"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL71470.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="131" mass="14552" checksum="515D829361F2C930" modified="2016-01-20" version="1">MPPEGWKNLDNNLIVSPKFDDRGLIPAIVQNAQTRQVLTLAYMNAESLRLTQQTGETHFWSRSRQELWHKGATSGNIQKVVEMTLDCDLDALLVRVIPAGPACHTGAVSCFFNPLPLTVSPTQIGEENHED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XA93</accession>
    <name>A0A0P6XA93_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Ornithine carbamoyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_03660</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the aspartate/ornithine carbamoyltransferase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061880.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03660"/>
    <dbReference type="EnsemblBacteria" id="KPL78999">
        <property type="protein sequence ID" value="KPL78999"/>
        <property type="gene ID" value="ADN00_03660"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.84"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016597">
        <property type="term" value="F:amino acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016743">
        <property type="term" value="F:carboxyl- or carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1370">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006132">
        <property type="entry name" value="Asp/Orn_carbamoyltranf_P-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006130">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036901">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006131">
        <property type="entry name" value="Asp_carbamoyltransf_Asp/Orn-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00185">
        <property type="entry name" value="OTCace"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02729">
        <property type="entry name" value="OTCace_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00100">
        <property type="entry name" value="AOTCASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53671">
        <property type="entry name" value="SSF53671"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="OTCace_N" evidence="4">
        <location>
            <begin position="8"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="OTCace" evidence="3">
        <location>
            <begin position="161"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL78999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="326" mass="37221" checksum="1E711E35DF538B0C" modified="2016-01-20" version="1">MISDLRGRDFITDLDFSVEEIDTILDVAWDLKRKRALREPTPYLRDKALAMLFFFASTRTRGAFETAAIHLGAIPAFIESRVTQISHGDTEREMGQIFGRMYDGIAIRHVEWGVGNKYVNLVAEASPVPVMNMQCEYYHPFQILTDLMTIMEQKGRNLRRKKMVMSWAYADSYQKPMSIPNSMVLQMPRFGVDLVLAHPKEFKLPDSTIEFAQETARKNGCGFEITDDMEAAFKDADIIYPKSWGPWMTTTDKDEAGKIIKQYESWICDERKMALAKEDAIYMHPLPADRNIEVTDAVLDGPQSVVFPEAENKMYIAEAVMALTMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAK6</accession>
    <name>A0A0P6XAK6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_02160</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000009">
        <property type="protein sequence ID" value="KPL79789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061320.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000009.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02160"/>
    <dbReference type="EnsemblBacteria" id="KPL79789">
        <property type="protein sequence ID" value="KPL79789"/>
        <property type="gene ID" value="ADN00_02160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="SSF54913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="121" mass="13486" checksum="75B857EFB8642A61" modified="2016-01-20" version="1">MFAVMFVLDDPNELDSILNAWEKAGITGVTIIESTGFHRWRTQRKHIPLLFDVQPVMVGAESGNYTLVTIVEKQELIDACVEATEKVVGKLTEPNTGVLMAWPLSMVCGIPKDRQKKEGNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAS3</accession>
    <name>A0A0P6XAS3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AP_endonuc_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062742.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77334">
        <property type="protein sequence ID" value="KPL77334"/>
        <property type="gene ID" value="ADN00_09445"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="1">
        <location>
            <begin position="29"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="320" mass="36604" checksum="6FE6D7B0B7A3A650" modified="2016-01-20" version="1">MFKIKQSLDAVNYGAYFYSGNPLTMEQVVDRAARFGYEAVDLWPHRPMSFPPDLSLEARKNLLSYANDKGIKFAAVDACTNFMRSDHVLVPHTEKELLYVRSCCELARDMDCKVVRILPAFIGYFWQDYWDKGYCQTAMHSRTLEVSTQDDYLREWESVRAGIIESGNIAKEFGVTLAVQGHPPVVNCVQDLIDLVDEVDMENVKIGLDLPLFDHQESEYIIKIVKSIGKRMVHSHTLGVKLKHGPSGVVYASEEVIPGDGIENWLPFFKACKEIGYEGYFAYEQCAPFLMPGHKKPTVEEFDRRQQVGFEFIKSFEEKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAT8</accession>
    <name>A0A0P6XAT8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">GTP 3',8-cyclase</fullName>
            <ecNumber evidence="3 12">4.1.99.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Molybdenum cofactor biosynthesis protein A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">moaA</name>
        <name evidence="14" type="ORF">ADN00_04745</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Catalyzes the cyclization of GTP to (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>AH2 + GTP + S-adenosyl-L-methionine = (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate + 5'-deoxyadenosine + A + H(+) + L-methionine</text>
            <dbReference type="Rhea" id="RHEA:49576"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:131766"/>
            <dbReference type="EC" id="4.1.99.22"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="12">Binds 2 [4Fe-4S] clusters. Binds 1 [4Fe-4S] cluster coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine and 1 [4Fe-4S] cluster coordinated with 3 cysteines and the GTP-derived substrate.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 12">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Monomer and homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the radical SAM superfamily. MoaA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.99.22" evidence="3 12"/>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061896.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04745"/>
    <dbReference type="EnsemblBacteria" id="KPL79246">
        <property type="protein sequence ID" value="KPL79246"/>
        <property type="gene ID" value="ADN00_04745"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.313"/>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019008">
        <property type="term" value="C:molybdopterin synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061798">
        <property type="term" value="F:GTP 3',8'-cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904047">
        <property type="term" value="F:S-adenosyl-L-methionine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01225_B">
        <property type="entry name" value="MoaA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013483">
        <property type="entry name" value="MoaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000385">
        <property type="entry name" value="MoaA_NifB_PqqE_Fe-S-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010505">
        <property type="entry name" value="Mob_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06463">
        <property type="entry name" value="Mob_synth_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02666">
        <property type="entry name" value="moaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01305">
        <property type="entry name" value="MOAA_NIFB_PQQE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9 12" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="7 12" id="KW-0408">Iron</keyword>
    <keyword evidence="8 12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="11 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 12" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="6 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 12" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="13">
        <location>
            <begin position="4"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="20"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="26"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="94"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="118"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="258"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-substrate</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="261"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-substrate</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="263"/>
            <end position="265"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="275"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-substrate</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KPL79246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="327" mass="36034" checksum="7139B092C398BC63" modified="2016-01-20" version="1">MRDTFGRQIEYLRISVTDRCNLRCVYCMPPEGVEKLGHEKIMHFEEIAEVVRVAAQYGVRAVRLTGGEPLVRKELPRLVRMIAETPGIEDVSLTTNGILLADLAAPLAEAGLKRVNVSLDTLDADKFTRITRVGSIENVWQGIAAAEKAGLAPLKINVVTMRGVNDDELMDMALLAKEHPWTVRFIELMPVKNQAPWGPGFPEPENAYISIQEMLQILEPLHLEPLTRKVGLGPAREYSLPGGMGKVGFISPVGDHFCAECNRLRLTADGNIRPCLLSDVEIPLLPALRAGESILPLLQQALRVKPEGHTLAEHITPHGRCMQQIGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAU0</accession>
    <name>A0A0P6XAU0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 13">Phosphoenolpyruvate-protein phosphotransferase</fullName>
            <ecNumber evidence="5 13">2.7.3.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 13">Phosphotransferase system, enzyme I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">ADN00_15865</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>L-histidyl-[protein] + phosphoenolpyruvate = N(pros)-phospho-L-histidyl-[protein] + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:23880"/>
            <dbReference type="Rhea" id="RHEA-COMP:9745"/>
            <dbReference type="Rhea" id="RHEA-COMP:9746"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:29979"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:64837"/>
            <dbReference type="EC" id="2.7.3.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 13 16">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the PEP-utilizing enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.3.9" evidence="5 13"/>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064009.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15865"/>
    <dbReference type="EnsemblBacteria" id="KPL72289">
        <property type="protein sequence ID" value="KPL72289"/>
        <property type="gene ID" value="ADN00_15865"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.878"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008965">
        <property type="term" value="F:phosphoenolpyruvate-protein phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008279">
        <property type="entry name" value="PEP-util_enz_mobile_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000121">
        <property type="entry name" value="PEP_util_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023151">
        <property type="entry name" value="PEP_util_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036637">
        <property type="entry name" value="Phosphohistidine_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024692">
        <property type="entry name" value="PTS_EI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006318">
        <property type="entry name" value="PTS_EI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008731">
        <property type="entry name" value="PTS_EIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036618">
        <property type="entry name" value="PtsI_HPr-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05524">
        <property type="entry name" value="PEP-utilisers_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00391">
        <property type="entry name" value="PEP-utilizers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02896">
        <property type="entry name" value="PEP-utilizers_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000732">
        <property type="entry name" value="PTS_enzyme_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47831">
        <property type="entry name" value="SSF47831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52009">
        <property type="entry name" value="SSF52009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01417">
        <property type="entry name" value="PTS_I_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00742">
        <property type="entry name" value="PEP_ENZYMES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0418">Kinase</keyword>
    <keyword evidence="13 16" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11 13 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 13" id="KW-0598">Phosphotransferase system</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 13" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="13" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 13" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PEP-utilisers_N" evidence="19">
        <location>
            <begin position="5"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers" evidence="17">
        <location>
            <begin position="155"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers_C" evidence="18">
        <location>
            <begin position="255"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="PEP binding" evidence="15">
        <location>
            <begin position="455"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="14">
        <location>
            <position position="190"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="14">
        <location>
            <position position="503"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="297"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="333"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="432"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="456"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="466"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00016544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR000732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000732-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR000732-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR000732-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF02896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF05524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KPL72289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="577" mass="62435" checksum="F41A6A06E663567E" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XB57</accession>
    <name>A0A0P6XB57_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH tetR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_10345</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062925.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76972">
        <property type="protein sequence ID" value="KPL76972"/>
        <property type="gene ID" value="ADN00_10345"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2535"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="37"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL76972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="253" mass="28237" checksum="7DA279974B163246" modified="2016-01-20" version="1">MSSQEYTIPLSAEQIYPLLLKLEDQGVITRTFRRLDPDRQQAVIDAILAEAAVSGPAGINIKHVAARSGVAVGSLYQYFGNREGLINFSIELVTRQVCETFNYIQPWLAEMPLREGLRAYIEGGEAWSEAQASFVRFFAAAAYNQNAEMQERVVRPVAAVMLENVRQMLAAALERGEVRADLDLEAAARLLHGMTIILGDSQILPYLNAYFQTSEEGVEWQRVMNVFLDVLTHGMLAVNQLNNENLGVETRES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XB84</accession>
    <name>A0A0P6XB84_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9 10">Multifunctional fusion protein</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="10">Glycine--tRNA ligase beta subunit</fullName>
                <ecNumber evidence="10">6.1.1.14</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="10">Glycyl-tRNA synthetase beta subunit</fullName>
                <shortName evidence="10">GlyRS</shortName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="9">Glycine--tRNA ligase alpha subunit</fullName>
            </recommendedName>
            <alternativeName>
                <fullName evidence="9">Glycyl-tRNA synthetase alpha subunit</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="9" type="primary">glyQ</name>
        <name evidence="10" type="synonym">glyS</name>
        <name evidence="12" type="ORF">ADN00_10530</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP + glycine + tRNA(Gly) = AMP + diphosphate + glycyl-tRNA(Gly)</text>
            <dbReference type="Rhea" id="RHEA:16013"/>
            <dbReference type="Rhea" id="RHEA-COMP:9664"/>
            <dbReference type="Rhea" id="RHEA-COMP:9683"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78522"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.14"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.14" evidence="10"/>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062958.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10530"/>
    <dbReference type="EnsemblBacteria" id="KPL76999">
        <property type="protein sequence ID" value="KPL76999"/>
        <property type="gene ID" value="ADN00_10530"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2577"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004814">
        <property type="term" value="F:arginine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004820">
        <property type="term" value="F:glycine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006420">
        <property type="term" value="P:arginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006426">
        <property type="term" value="P:glycyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00733">
        <property type="entry name" value="GlyRS_alpha_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00254">
        <property type="entry name" value="Gly_tRNA_synth_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00255">
        <property type="entry name" value="Gly_tRNA_synth_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008909">
        <property type="entry name" value="DALR_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015944">
        <property type="entry name" value="Gly-tRNA-synth_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006194">
        <property type="entry name" value="Gly-tRNA-synth_heterodimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002310">
        <property type="entry name" value="Gly-tRNA_ligase_asu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30075">
        <property type="entry name" value="PTHR30075"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05746">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02091">
        <property type="entry name" value="tRNA-synt_2e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02092">
        <property type="entry name" value="tRNA_synt_2f"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01044">
        <property type="entry name" value="TRNASYNTHGA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00388">
        <property type="entry name" value="glyQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00211">
        <property type="entry name" value="glyS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50861">
        <property type="entry name" value="AA_TRNA_LIGASE_II_GLYAB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DALR_1" evidence="11">
        <location>
            <begin position="890"/>
            <end position="982"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF05746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KPL76999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="996" mass="110740" checksum="98BEE6D302882C82" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBA6</accession>
    <name>A0A0P6XBA6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ABC transmembrane type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_10715</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062991.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77027">
        <property type="protein sequence ID" value="KPL77027"/>
        <property type="gene ID" value="ADN00_10715"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2618"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="111"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="165"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="216"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="269"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="74"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL77027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="301" mass="34113" checksum="2409409230E6DBFD" modified="2016-01-20" version="1">MQSAYPSRVRQYLPVLLFLLPGIILFLTFIIGPMLYSLRISFYDWNIVKPERSVFVGFENYQRALADPIFRKAALNTLVYTLVTVPAQMLLGLLVAMLLNQKFHGRVFFRVAYYLPVITSWVIVSLLFEYMFSGQAGLINYLLRDVFGLIQQNIRWLADPVLTFVPIHLLGIWKGVGWTAVIFLAGLQAIPQELYEAAEVDGANTFNKFWYITLPLLRSTLIFLLVVLVIGGLNAYISNLLITDGGNPLDLTHFVLTLMYEATFTKLDFGYGSAISYLLTVVVFVVSVFQIQLLQKQSAEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBB1</accession>
    <name>A0A0P6XBB1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10765</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063001.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10765"/>
    <dbReference type="EnsemblBacteria" id="KPL77036">
        <property type="protein sequence ID" value="KPL77036"/>
        <property type="gene ID" value="ADN00_10765"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021683">
        <property type="entry name" value="DUF3267"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11667">
        <property type="entry name" value="DUF3267"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="186" mass="20493" checksum="2BF168F56D9E4CB1" modified="2016-01-20" version="1">MNSAPPARTEYAVSMLAANLYGLAIGLPLLAACGWAYTARWGFSPLARALEWSFPRPLILLGLFLGGILAHEWLHGLSWVLFGRLRLSDLHFGVEWKTLTPYAHVKTPLDVNIYRLGTMMPGLVVGLLPYLYGLWSGEAGWMLWGAVFTFAASGDFLVLWLLRQVPPASQVEDHPTKAGCWVIPSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBE8</accession>
    <name>A0A0P6XBE8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH cro/C1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10685</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10685"/>
    <dbReference type="EnsemblBacteria" id="KPL77081">
        <property type="protein sequence ID" value="KPL77081"/>
        <property type="gene ID" value="ADN00_10685"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2611"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="19"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="206" mass="22945" checksum="201304884CBB32F7" modified="2016-01-20" version="1">MNPAIGFASGSAVNVGEKLYQLRSWRGYSIRHLAEMSGLAINTLSLIENGKTSPSVSTLQQVAMALEVPITAFFEMDAEKQAVICSSNQKREQAQLQDTTIEDLSLGKYSGNVQALLVTLPPESQCGERNIVHNGHEIVFCLSGRVHYRVDGQIYVLEENDSLMFEAHLPHCWKNEENVPARLLLVMVPNDPREKAIERHFGPLNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XC74</accession>
    <name>A0A0P6XC74_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_08155</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08155"/>
    <dbReference type="EnsemblBacteria" id="KPL77846">
        <property type="protein sequence ID" value="KPL77846"/>
        <property type="gene ID" value="ADN00_08155"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.632"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004792">
        <property type="entry name" value="BaiN-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023166">
        <property type="entry name" value="HI0933-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42887">
        <property type="entry name" value="PTHR42887"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00275">
        <property type="entry name" value="TIGR00275"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL77846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="397" mass="42348" checksum="EF2D963D6D35E4B2" modified="2016-01-20" version="1">MAAWQAAKHGTRVVLFDSNARPGKKLLITGSGRCNLSNTKCAPERYTCDESDFLSRAWAEFSQADLVNLLGELGIPLYATDDGWYYPLSNSAANVAEILIELLVAAGVEFVPESRVVQISPAGYGFKVYCGNKEKPVYVDSLVVASGGKAYPQTGSDGSLFPIIRGLGHRILPTRPALAPVLLEGGTTSLLKGVRLDAGCMLVKNEKVVESTVGNVIFTEWGMNGPGVMDLSHWIEKPEQEDYRLVVNFLPGKESLLFDFLQQGAQNGLSTRAVLLGLLPEKVVSWAMDGLDIEPNQLAGDLSPEQANTLARKLTSTSLKVLGVKGYSHAQCSTGGVAVSEVNGSTMESKIVPGIFFAGEVLNVNGPCGGYNLHWALTSGRIAGRGAALRGKMSSLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XD62</accession>
    <name>A0A0P6XD62_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000003">
        <property type="protein sequence ID" value="KPL80849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80849">
        <property type="protein sequence ID" value="KPL80849"/>
        <property type="gene ID" value="ADN00_01280"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="76" mass="8547" checksum="C256802397AB090C" modified="2016-01-20" version="1">MFAMNHPAEPLQLSPEEQGRLLARVYAFILSDQFIGTQQEPYNQLGKQPTKERKKSTTGNATDIDAETIANQEPNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDK9</accession>
    <name>A0A0P6XDK9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Excinuclease ABC subunit A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">uvrA</name>
        <name evidence="15" type="ORF">ADN00_07620</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062382.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07620"/>
    <dbReference type="EnsemblBacteria" id="KPL78312">
        <property type="protein sequence ID" value="KPL78312"/>
        <property type="gene ID" value="ADN00_07620"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3353"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009380">
        <property type="term" value="C:excinuclease repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004602">
        <property type="entry name" value="UvrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041552">
        <property type="entry name" value="UvrA_DNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17755">
        <property type="entry name" value="UvrA_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00630">
        <property type="entry name" value="uvra"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="9 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6" id="KW-0228">DNA excision</keyword>
    <keyword evidence="12" id="KW-0234">DNA repair</keyword>
    <keyword evidence="11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ABC transporter" evidence="14">
        <location>
            <begin position="511"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="543"/>
            <end position="550"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KPL78312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="843" mass="91282" checksum="661C9CCEE30352BC" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDN3</accession>
    <name>A0A0P6XDN3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Response regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_07730</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062404.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07730"/>
    <dbReference type="EnsemblBacteria" id="KPL78331">
        <property type="protein sequence ID" value="KPL78331"/>
        <property type="gene ID" value="ADN00_07730"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="3"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="127" mass="13874" checksum="92F3C3FE49E744DD" modified="2016-01-20" version="1">MTTILLADHDPKVRSAMRLLLEQQPQCGQIIELESSDGLVDKALEHRAKIVILEWELPGVTTNAQLITQLRREIENVKIVSISGRERVGQLAMALGANAFINKSDSPDKLLDCVQKCCGDHSAEGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDX4</accession>
    <name>A0A0P6XDX4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Phosphoenolpyruvate carboxykinase (ATP)</fullName>
            <shortName evidence="8">PCK</shortName>
            <shortName evidence="8">PEP carboxykinase</shortName>
            <shortName evidence="8">PEPCK</shortName>
            <ecNumber evidence="4 8">4.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">pckA</name>
        <name evidence="9" type="ORF">ADN00_00320</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Involved in the gluconeogenesis. Catalyzes the conversion of oxaloacetate (OAA) to phosphoenolpyruvate (PEP) through direct phosphoryl transfer between the nucleoside triphosphate and OAA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + oxaloacetate = ADP + CO2 + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:18617"/>
            <dbReference type="ChEBI" id="CHEBI:16452"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.1.1.49"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="8">Binds 1 Mn(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the phosphoenolpyruvate carboxykinase (ATP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.49" evidence="4 8"/>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00320"/>
    <dbReference type="EnsemblBacteria" id="KPL81139">
        <property type="protein sequence ID" value="KPL81139"/>
        <property type="gene ID" value="ADN00_00320"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3457"/>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004612">
        <property type="term" value="F:phosphoenolpyruvate carboxykinase (ATP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.449.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.228.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00453">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001272">
        <property type="entry name" value="PEP_carboxykinase_ATP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013035">
        <property type="entry name" value="PEP_carboxykinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008210">
        <property type="entry name" value="PEP_carboxykinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015994">
        <property type="entry name" value="PEPCK_ATP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30031">
        <property type="entry name" value="PTHR30031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01293">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006294">
        <property type="entry name" value="PEP_crbxkin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68923">
        <property type="entry name" value="SSF68923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00532">
        <property type="entry name" value="PEPCK_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="8" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="7 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="8">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="195"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="214"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="230"/>
            <end position="238"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="279"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="317"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="437"/>
            <end position="438"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="443"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL81139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="513" mass="56565" checksum="14B42224BA8C9043" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XFP2</accession>
    <name>A0A0P6XFP2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Carbamate kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_03655</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the carbamate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061609.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03655"/>
    <dbReference type="EnsemblBacteria" id="KPL78998">
        <property type="protein sequence ID" value="KPL78998"/>
        <property type="gene ID" value="ADN00_03655"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.83"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008804">
        <property type="term" value="F:carbamate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006525">
        <property type="term" value="P:arginine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04235">
        <property type="entry name" value="AAK_CK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003964">
        <property type="entry name" value="Carb_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30409">
        <property type="entry name" value="PTHR30409"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000723">
        <property type="entry name" value="Carbamate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00746">
        <property type="entry name" value="arcC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AA_kinase" evidence="3">
        <location>
            <begin position="5"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR000723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL78998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="319" mass="34297" checksum="C0CE0D84F9155AE0" modified="2016-01-20" version="1">MSEKKVAVVAIGGNSLILDKKRQSVEDQYAAAQETAKHIVDMIEAGWDVAIGHGNGPQVGFILRRSEIAHKVEGMHEVPLDVCGADSQGAIGYAITQNMQNELKKRGINKPVATIITQVRVDADDKAFEHPSKPIGGFMDEPEAMKRKEELGWSVVEDSGRGWRRVVASPIPQEVVELDSVKTLIDAGVIVVTVGGGGIPVIRNADGELKGTAAVIDKDFASSLLAREINADLLLISTAVEKVYLNFGKPDQKALDRITLSEAKQYLAEGTHFAKGSMAPKIQAIIWFLEAGGKSALITDPANIGRALRGETGTWIMPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XG81</accession>
    <name>A0A0P6XG81_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NTP_transf_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_18735</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064565.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18735"/>
    <dbReference type="EnsemblBacteria" id="KPL70081">
        <property type="protein sequence ID" value="KPL70081"/>
        <property type="gene ID" value="ADN00_18735"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002934">
        <property type="entry name" value="Polymerase_NTP_transf_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01909">
        <property type="entry name" value="NTP_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NTP_transf_2" evidence="1">
        <location>
            <begin position="19"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="96" mass="11028" checksum="8CAED02E9CA46238" modified="2016-01-20" version="1">MEKEAIFETLKNVKAELYNRGVNSISIFGSVARGQYNDDSDLDILVSFCKPVGLFEFIRLKAYLEKLTNRRVDLVTIDALRPEMKDQILQEAVHVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGA4</accession>
    <name>A0A0P6XGA4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PTS_IIB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_05545</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78709.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05545"/>
    <dbReference type="EnsemblBacteria" id="KPL78709">
        <property type="protein sequence ID" value="KPL78709"/>
        <property type="gene ID" value="ADN00_05545"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1586"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008982">
        <property type="term" value="F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036095">
        <property type="entry name" value="PTS_EIIB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003501">
        <property type="entry name" value="PTS_EIIB_2/3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02302">
        <property type="entry name" value="PTS_IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52794">
        <property type="entry name" value="SSF52794"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PTS_IIB" evidence="2">
        <location>
            <begin position="13"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78709.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="109" mass="11555" checksum="04006BE2683CFB03" modified="2016-01-20" version="1">MSQSISASQVNTIIFACEAGMGSSLMSVNALKKKLKAAQVKDVTVVHKPVRDIPSDAQVVVVHKGLAKTAHAKAPNAVIVAFNHFLNDPIFDQLVNAMVTKAEIVGADF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGW7</accession>
    <name>A0A0P6XGW7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_03725</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061621.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03725"/>
    <dbReference type="EnsemblBacteria" id="KPL79011">
        <property type="protein sequence ID" value="KPL79011"/>
        <property type="gene ID" value="ADN00_03725"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018652">
        <property type="entry name" value="DUF2082_NA-bd_Znr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09855">
        <property type="entry name" value="zinc_ribbon_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="81" mass="9087" checksum="125F4FA94EBEB091" modified="2016-01-20" version="1">MAKNVDQMLASKFVCEKCHHQGATVERLAMSGTGLSRMLEIQAHRYAFVSCNNCGHTEVYNLRTLEGSDDLGHLLEILFMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XHU1</accession>
    <name>A0A0P6XHU1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Putative_PNPOx domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_02920</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000013">
        <property type="protein sequence ID" value="KPL79395.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061458.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000013.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02920"/>
    <dbReference type="EnsemblBacteria" id="KPL79395">
        <property type="protein sequence ID" value="KPL79395"/>
        <property type="gene ID" value="ADN00_02920"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011576">
        <property type="entry name" value="Pyridox_Oxase_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01243">
        <property type="entry name" value="Putative_PNPOx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Putative_PNPOx" evidence="2">
        <location>
            <begin position="34"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79395.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="172" mass="19807" checksum="F0F219DB09B9A758" modified="2016-01-20" version="1">MNAKSDSRKASRPLMPKDYGVPQGEDTLLPWETVEEQLQKERIFWVCTVRPDGRPHTVPLWGAWFNERFYFDGSPETRHVRNLMANPAVSVHLESGEEVVIIEGTGRAVGKPPRELALGLYEIYRGKYAGWPGYEPTPEMWDEGGLYEIVPQRVLAWRNFPSDATRWVFESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XHW6</accession>
    <name>A0A0P6XHW6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_02585</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000012">
        <property type="protein sequence ID" value="KPL79422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061399.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000012.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79422">
        <property type="protein sequence ID" value="KPL79422"/>
        <property type="gene ID" value="ADN00_02585"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2343"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038729">
        <property type="entry name" value="Rad50/SbcC_AAA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13304">
        <property type="entry name" value="AAA_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13476">
        <property type="entry name" value="AAA_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_23" evidence="2">
        <location>
            <begin position="38"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="ATPase_AAA_core" evidence="1">
        <location>
            <begin position="219"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="499" mass="55970" checksum="F20C26FA01D2814E" modified="2016-01-20" version="1">MPRVNLSQAEKDLIERWKIAARYQTPRLSGLAIEGNDGIRGIRNLAVNFDRPITVICGKNGCGKSTLISLSRLGFQQDHQLDDLFLEINNPHPFNDFSVHWSYLKHDPPQISLDGGTSTYSTPPPAKNVVYIGLSRIAPAWENTALTAHFRQQPVWESQNQLEPRNLERLRDILNKPFTGAGWGKSGAYEMRTCSTHATYTSFNMCTGEEMLVEMIRLLQQAEVESLVLIEDAEIGLNPVVMPRFARHLVEICESKRLQVILSTHSLDLITAFPSELVCLIKSDGAAHQAKDNPEMQEIFTSISSQVESDVIIFCEDDVAESLIRQAVSGDLRRRLKVVYGSKTKLLAYAEAHLKAGWPQIPLIVWDGDVNDNEVKKWLDSLDQMTRDELSAKVSRIKLPGELPPERWMLTQLDTDEGCQLLAEELNEDVPTTKAFLGMLSTMTAFHSLSYELAERTGLDEKAVLRSLTRSIGRLSTDPLAPLREQIGKAVNKEIIQVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XJW0</accession>
    <name>A0A0P6XJW0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_12385</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063327.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76129">
        <property type="protein sequence ID" value="KPL76129"/>
        <property type="gene ID" value="ADN00_12385"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="270" mass="30909" checksum="88833F9ADCC55638" modified="2016-01-20" version="1">MPAVPLNQIQAQIAELSWKYTRAPEYVEGLRDLFNQYGSLVFKKGQVTRKLRAYPSFHVPPVLMNQLEMSLIANHRRYPQASLALVDALWQEEMIEPKTLAAALLGRVDVGEPEPIMQRILLWCQPDLHPLVQEVVFDHATLTLRERYAAVWLAQIEAWADHPTQTIQNMGLRAMLPLAKDRQFNNLPPLFRLLTPLVQSFTPDQQPVLAELITALARRTPVEMSFLLRQICQRGVSSASLRMLRRLLPIFPLHEQEQLRQAIKDASPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKG4</accession>
    <name>A0A0P6XKG4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_11060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063073.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76504">
        <property type="protein sequence ID" value="KPL76504"/>
        <property type="gene ID" value="ADN00_11060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="153" mass="16529" checksum="87233A9F9D6D1D19" modified="2016-01-20" version="1">MIFDLPRKWNLAVIQSTPLPGLILAALFFVALLAVIWSGGVALSAEDAAVNDFPVQPVDDWLRSVQAGDAGSAYAGLSTHLQSSFESPASFAAYLNELGLSPQGWMVQSPQAREDRVVVSAKIAQQDGQLRNLGLIYVREGGAWKIDLITFEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKK0</accession>
    <name>A0A0P6XKK0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_11375</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TMEM86 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11375"/>
    <dbReference type="EnsemblBacteria" id="KPL76587">
        <property type="protein sequence ID" value="KPL76587"/>
        <property type="gene ID" value="ADN00_11375"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.975"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012506">
        <property type="entry name" value="YhhN"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31885">
        <property type="entry name" value="PTHR31885"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07947">
        <property type="entry name" value="YhhN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="42"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="156"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL76587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="217" mass="23741" checksum="D3101E1A0851D84F" modified="2016-01-20" version="1">MNWWAVDRRQRRWVLVTKPAMMLFLIAWTGGFALERGVAGELAWLLAGLGLSLAGDVLLMGNGLGFFKAGLLAFLLAHIAYIAHFWPLVPAMAWPAALVLVGLLAVFGWRFGARVHRGLLETGRLRLFRAVAAYTLVISVMVLSAALRWLDAQWPPLAAGGALLGALLFFTSDVLNARRRFIAHFAHEELWVMSTYHLGQILLAVSAVIKISQGGVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKK8</accession>
    <name>A0A0P6XKK8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_16450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064131.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72065">
        <property type="protein sequence ID" value="KPL72065"/>
        <property type="gene ID" value="ADN00_16450"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3733"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="238"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="271" mass="30161" checksum="9C43BB2F2C4953D7" modified="2016-01-20" version="1">MQKIHEFAKNKPVLFSLLALVLGVVLTEIPLKTLLSPYTGDQIAHYVTLILEQGLTGLLFFWLIKRFNWLDTAGFTPFKKWKSLWLGWPLLLFTLINVEEGIVIDTSKPLLIVLHLLTALSTGWVEEVLCRGVVVTALLKKWGSSRKGIYLSVLVASVLFGLAHLTNFLAGRKPLLNNVTQVIFCIFFGVIFAACILRNRTIWPMIVLHAAVDWAATLREISIGGGLRTEVPVMSIESAVVSILITLPLFIYGLIILRKVEPASLNLEMSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKR5</accession>
    <name>A0A0P6XKR5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosome hibernation promoting factor</fullName>
            <shortName evidence="2">HPF</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">hpf</name>
        <name evidence="4" type="ORF">ADN00_15235</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Required for dimerization of active 70S ribosomes into 100S ribosomes in stationary phase; 100S ribosomes are translationally inactive and sometimes present during exponential growth.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Interacts with 100S ribosomes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the HPF/YfiA ribosome-associated protein family. Long HPF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063895.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15235"/>
    <dbReference type="EnsemblBacteria" id="KPL72184">
        <property type="protein sequence ID" value="KPL72184"/>
        <property type="gene ID" value="ADN00_15235"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044238">
        <property type="term" value="P:primary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00552">
        <property type="entry name" value="RaiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.505.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00839">
        <property type="entry name" value="HPF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034694">
        <property type="entry name" value="HPF_long/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036567">
        <property type="entry name" value="RHF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003489">
        <property type="entry name" value="RHF/RaiA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032528">
        <property type="entry name" value="Ribosom_S30AE_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038416">
        <property type="entry name" value="Ribosom_S30AE_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16321">
        <property type="entry name" value="Ribosom_S30AE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02482">
        <property type="entry name" value="Ribosomal_S30AE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69754">
        <property type="entry name" value="SSF69754"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00741">
        <property type="entry name" value="yfiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0810">Translation regulation</keyword>
    <feature type="domain" description="Ribosom_S30AE_C" evidence="3">
        <location>
            <begin position="129"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL72184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="190" mass="21779" checksum="FD8B035F4205DE07" modified="2016-01-20" version="1">MALEVEIFARNMELTDRINEYVEKKVSKMDRYLNNIEETRVDLSYNKSARSASDRHISEITIRGKGFILRAEERADDIFAALDKSLDKIQRQIERYKGKRNRGRGDGVPASSLAAEISATEAPDEAEAAPIIARRKQFTLIPMDEMEAIEQMKLLGHENFFIFYNVNTSEINILYTRRDGTYGLIEPKIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XLQ2</accession>
    <name>A0A0P6XLQ2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Trk system potassium uptake protein TrkA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_12140</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063283.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12140"/>
    <dbReference type="EnsemblBacteria" id="KPL76087">
        <property type="protein sequence ID" value="KPL76087"/>
        <property type="gene ID" value="ADN00_12140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015079">
        <property type="term" value="F:potassium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006036">
        <property type="entry name" value="K_uptake_TrkA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02080">
        <property type="entry name" value="TrkA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02254">
        <property type="entry name" value="TrkA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00335">
        <property type="entry name" value="KUPTAKETRKA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51201">
        <property type="entry name" value="RCK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0630">Potassium</keyword>
    <keyword evidence="2" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="RCK N-terminal" evidence="5">
        <location>
            <begin position="2"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="6">
        <location>
            <begin position="139"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00017378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL76087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="223" mass="24027" checksum="31B0D43F8E3A068B" modified="2016-01-20" version="1">MFVMIVGGGNVGMHLASFLLDQGYKVKIVENRPEMISRLERKLPKEVIVFGSGSDPNVLESADIRHVDVMVAATGQDETNLVVSSLAKLEFGVPRVIGRVNNPLNAWLYTIDMGVDVALNQAELIGTLVAEQMSLGDMMTLLRLRKGKFSIVEEKVAPGAPADGKALKDIKFPNDCTITAVIRDGSLIVPHGDTILQTTDEVLALVSTEQIPVLAALLGKPIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XLV5</accession>
    <name>A0A0P6XLV5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PALP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_01085</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000003">
        <property type="protein sequence ID" value="KPL80817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061117.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01085"/>
    <dbReference type="EnsemblBacteria" id="KPL80817">
        <property type="protein sequence ID" value="KPL80817"/>
        <property type="gene ID" value="ADN00_01085"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1961"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000634">
        <property type="entry name" value="Ser/Thr_deHydtase_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00165">
        <property type="entry name" value="DEHYDRATASE_SER_THR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PALP" evidence="3">
        <location>
            <begin position="19"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL80817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="328" mass="34484" checksum="0C1C585BF6018E65" modified="2016-01-20" version="1">MLQDLELTLKHIYEARQLISPHIRKTPLLEMPELSALAEAPVLAKAENLQITGSFKIRGAANKLLHLTPQQKAKGVLTCSSGNHGRALSLMAQKLGVHAVVCITEAVPPNKRQAILDLGGELIVGGKTADDALIFADQLEVERGLTMTHSFDDPNAITGQGTIGLEIMEDAPQVDTFVVPLSGGSLLSGIALAVKSANPKARVIGVSMQRAPVMIESLKAGHVVEIPEEPTLADGLAGGIGLNNTWTFRYVQRLADETITVSEEEIASAMFHALHHHHLVLEGAGAVGLAALLAGKVKSSGQGIAVVLSGGNVNLPVLIKIASQKLAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XM69</accession>
    <name>A0A0P6XM69_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cobalt ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_18255</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064484.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18255"/>
    <dbReference type="EnsemblBacteria" id="KPL70009">
        <property type="protein sequence ID" value="KPL70009"/>
        <property type="gene ID" value="ADN00_18255"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2957"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03225">
        <property type="entry name" value="ABC_cobalt_CbiO_domain1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015856">
        <property type="entry name" value="ABC_transpr_CbiO/EcfA_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="6"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="303"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="40"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="336"/>
            <end position="343"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL70009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="568" mass="63457" checksum="6F85E7F8C4DC9D23" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XME8</accession>
    <name>A0A0P6XME8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Amylosucrase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_14980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000036">
        <property type="protein sequence ID" value="KPL73089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063842.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000036.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL73089">
        <property type="protein sequence ID" value="KPL73089"/>
        <property type="gene ID" value="ADN00_14980"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1860"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047669">
        <property type="term" value="F:amylosucrase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11324">
        <property type="entry name" value="AmyAc_Amylosucrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044077">
        <property type="entry name" value="Amylosucrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032091">
        <property type="entry name" value="Malt_amylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045857">
        <property type="entry name" value="O16G_dom_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16657">
        <property type="entry name" value="Malt_amylase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aamy" evidence="1">
        <location>
            <begin position="112"/>
            <end position="562"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL73089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="648" mass="75178" checksum="EF060AC82D93609B" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XNH4</accession>
    <name>A0A0P6XNH4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Methyltransferase</fullName>
            <ecNumber evidence="6">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_14730</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = an N(4)-methyl-2'-deoxycytidine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:16857"/>
            <dbReference type="Rhea" id="RHEA-COMP:11369"/>
            <dbReference type="Rhea" id="RHEA-COMP:13674"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:85452"/>
            <dbReference type="ChEBI" id="CHEBI:137933"/>
            <dbReference type="EC" id="2.1.1.113"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="6"/>
    <dbReference type="EMBL" id="LGCL01000035">
        <property type="protein sequence ID" value="KPL73592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063793.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000035.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14730"/>
    <dbReference type="REBASE" id="132877">
        <property type="entry name" value="M.OapP3M1ORF14730P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL73592">
        <property type="protein sequence ID" value="KPL73592"/>
        <property type="gene ID" value="ADN00_14730"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015667">
        <property type="term" value="F:site-specific DNA-methyltransferase (cytosine-N4-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002941">
        <property type="entry name" value="DNA_methylase_N4/N6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017985">
        <property type="entry name" value="MeTrfase_CN4_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001091">
        <property type="entry name" value="RM_Methyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01555">
        <property type="entry name" value="N6_N4_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00508">
        <property type="entry name" value="S21N4MTFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00093">
        <property type="entry name" value="N4_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N6_N4_Mtase" evidence="7">
        <location>
            <begin position="50"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL73592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="471" mass="53721" checksum="93798B02F94BEF8B" modified="2016-01-20" version="1">MGEKLIYNSGKMIQLPLKLIARSTNKMISKKTRLVELLAGDLNFHNSDSLYASHNFHSFPAKFPPQLPRVFIENLTNQNGVVLDPMMGSGTTIIETLIANRNCIGFDIDPLAILIARVKTTPVDPSEIMVITKKVISESKSLFDNGLDYLKEYYFENWDSKTRDFIDYWFDEITKYQLLSLIFFINKIQKESLKNFLKVAFSSIIITKNGGVSLALDLAHTRPHRAKYVKSQDGTVIIDKVESEQINSYTSKSIRSPFNEIEKKVINNLKGILPQSINTRSLILGNTQNSPLANNSVDLIVTSPPYASNAIDYMRAHKFSLIWFGYSIEYLSQKRDEYIGGELTKQCAFEPLPKFTESIVQEISNVDAKKGLVLRRYYSEMTRTIREMYRILKNDSAAIVVVGSSIMRNIDTQTQLCLAEIGKSSGFDVPKIGIRYIDRNRRMLPTSKKVDLESQIQKRMHEEYVIGLYKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XP07</accession>
    <name>A0A0P6XP07_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10475</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062949.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76992">
        <property type="protein sequence ID" value="KPL76992"/>
        <property type="gene ID" value="ADN00_10475"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="177" mass="19948" checksum="55633EEF84947853" modified="2016-01-20" version="1">MLIRNAQQEDARAIALVRVDSWRTTYRGLLPASFLNGLSYRDVEHYWNGILADPAQHGWAFVAEADGGQVVGFSLCGRTRDPLLPLEGELFALYLLQSHQRRGIGRQLFLAAVNQLRRAKLRGMLVWALETNQTARAFYERMGGVPAGQKNAVFGGMRVIQVAYRWDDLSQWDAESP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XPV6</accession>
    <name>A0A0P6XPV6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062686.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09125"/>
    <dbReference type="EnsemblBacteria" id="KPL77285">
        <property type="protein sequence ID" value="KPL77285"/>
        <property type="gene ID" value="ADN00_09125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01547">
        <property type="entry name" value="SBP_bac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133165" evidence="1">
        <location>
            <begin position="21"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="461" mass="49437" checksum="6CF141A3E98D03A0" modified="2016-01-20" version="1">MRTKLFVVLMLLSIVLSACAAPAATQEAAVPEAPAAEAPAATEAPAAVEAPAAAEAKTLKVYLLDYTPDTIAWLKSDINPAFEAAHPGVTVEITEGTWSGWDTTFSGFFAAGEGPDIINLGSEMNTLYGESLADMEEYLGEAAWPDIANFGPALENAKYDGKLRGLPIFTAPRYVFCRTDLMEASGWTTGTPQNFAEWVDFAGKASKIDPATNSLVQQALVPVDAGSMADWQWWLLVYYSLGGELYKADGTPNFDSPEALATTQFMLDMRQAIYGPAADAVGALPTGQGSVIDVNDETGVDNGAVCLAHSGWAAPAFDRPVWENVSIDPFFGDPANFPNSKPVVLAFNDWLAVADYSPNKELAAEWLKMAFSKEANHKWNETMSLIPARNDAQYGYVADSPQLAREAELASQYGVGFAGIEEAAKLSTIMQDALGKLITEELTPEDVVAKIQEEYTTALGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQ23</accession>
    <name>A0A0P6XQ23_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">M20_dimer domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_06360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06360"/>
    <dbReference type="EnsemblBacteria" id="KPL78836">
        <property type="protein sequence ID" value="KPL78836"/>
        <property type="gene ID" value="ADN00_06360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="1">
        <location>
            <begin position="190"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="445" mass="49351" checksum="68457F5D99314BCA" modified="2016-01-20" version="1">MIPSEIRKEASHHLQNLIRVNTSNPPGNEMQAVNYLAAIARENELDYEVFETFPGRGNILIKLLSHPSEKPPLVMISHLDVVPANPEQWSIDPFAGLEQNGIIWGRGAIDAKQLTVMQLMVLLLIKRRKFSPNRDIYLLATADEETGSRLGMMTMIERVPHIFRNADVISEGGGFPISVGSKVFYLCETGQKGSATLRFAFPKTPHSNPYLPDNDPILACSQLILKLRDFHWPGKLPETTHYLIDQLSAACKIPTSLALMDRLNQIGKTVSPALLNLLTAMTRNTITATVWSGGKQNRNIKYATELLVDVRTLPGVDRSQLESVISDLTTELPVEVEITRFNPGYESSFTSALFTSMSDAIKNRFPAADVVPFIATGASDGRFLQNFNANVSGFSPVLIEDMTFEKAVSMVHGVDERISVESLLFGIEVLYDAVTKSCQEKIYVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQH5</accession>
    <name>A0A0P6XQH5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_03820</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061639.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03820"/>
    <dbReference type="EnsemblBacteria" id="KPL79028">
        <property type="protein sequence ID" value="KPL79028"/>
        <property type="gene ID" value="ADN00_03820"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.117"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041575">
        <property type="entry name" value="Rubredoxin_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18267">
        <property type="entry name" value="Rubredoxin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="4">
        <location>
            <begin position="2"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="Rubredoxin_C" evidence="5">
        <location>
            <begin position="312"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF18267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL79028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="404" mass="43523" checksum="50E794F17EAECE13" modified="2016-01-20" version="1">MRYVIVGGGLAGATAAQALRRLDAQGEVHLYAAEPYPYYFRPRLWELIAGSAKEEEVFFRPAEWYADQGIHLHLGQAVGEILPEAHEIELAGGERIGYDRLLLATGGRPYVPPFLGSDLPRVVTLRTLEDAHNLIEISKKAEEMVVIGGGLLGLETAYSLMQRGVNVTVLEVFPRLLPRQLDEPGAALLQSSLEGMGFRFVLGSEPQEITLAGDVLAVETRDGRCLEGEAVLISAGVRSNTDLAKAAGLAVNYGVVVNEFLQSSAADVYAAGDAAEFENKVYGIIPAASEQASAAAANMVNPGSQAYTGTLPSTRLKVVGVQLASLGEATAEDADCEILRRVDEASGRYTRLTLRGQRLTGAILMGDTSAFMPIKRLIDRKKDVSAVKERLLDDNFDLKAFSME</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQW7</accession>
    <name>A0A0P6XQW7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">IPT/TIG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_04985</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061851.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04985"/>
    <dbReference type="EnsemblBacteria" id="KPL79201">
        <property type="protein sequence ID" value="KPL79201"/>
        <property type="gene ID" value="ADN00_04985"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.365"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014756">
        <property type="entry name" value="Ig_E-set"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002909">
        <property type="entry name" value="IPT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01833">
        <property type="entry name" value="TIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81296">
        <property type="entry name" value="SSF81296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133180" description="IPT/TIG domain-containing protein" evidence="2">
        <location>
            <begin position="30"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="domain" description="IPT/TIG" evidence="3">
        <location>
            <begin position="55"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL79201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="657" mass="68953" checksum="5902F3971E26B3B7" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XRA8</accession>
    <name>A0A0P6XRA8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glycogen synthase</fullName>
            <ecNumber evidence="7">2.4.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Starch [bacterial glycogen] synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">glgA</name>
        <name evidence="10" type="ORF">ADN00_15190</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Synthesizes alpha-1,4-glucan chains using ADP-glucose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>[(1-&gt;4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1-&gt;4)-alpha-D-glucosyl](n+1) + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18189"/>
            <dbReference type="Rhea" id="RHEA-COMP:9584"/>
            <dbReference type="Rhea" id="RHEA-COMP:9587"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15444"/>
            <dbReference type="ChEBI" id="CHEBI:57498"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.4.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Glycan biosynthesis; glycogen biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.21" evidence="7"/>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063886.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15190"/>
    <dbReference type="EnsemblBacteria" id="KPL72176">
        <property type="protein sequence ID" value="KPL72176"/>
        <property type="gene ID" value="ADN00_15190"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.740"/>
    <dbReference type="UniPathway" id="UPA00164"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033201">
        <property type="term" value="F:alpha-1,4-glucan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004373">
        <property type="term" value="F:glycogen (starch) synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009011">
        <property type="term" value="F:starch synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00484">
        <property type="entry name" value="Glycogen_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011835">
        <property type="entry name" value="GS/SS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013534">
        <property type="entry name" value="Starch_synth_cat_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08323">
        <property type="entry name" value="Glyco_transf_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02095">
        <property type="entry name" value="glgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0320">Glycogen biosynthesis</keyword>
    <keyword evidence="4 7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_transf_5" evidence="9">
        <location>
            <begin position="10"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="8">
        <location>
            <begin position="299"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="22"/>
        </location>
        <ligand>
            <name>ADP-alpha-D-glucose</name>
            <dbReference type="ChEBI" id="CHEBI:57498"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF08323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL72176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="493" mass="54797" checksum="5E3C4C0453022FC3" modified="2016-01-20" version="1">MPENASTISVLFAAAEADPFAKVGGLGDVAGALPVALQKLSEQAGRPRLDVRVVIPFHPVIRNKGFTPELVAEVLVSSISGDQKAQIYTQTINNVPVYLIDGEPVQKISPVYSSNNAVDAEKYVFFCQAALQMLLKLNWIPDVINANDWHTAPMIYALSLLKKGSASHPLKKVHTVFTIHNLPFMGAGAEKWMAHYHLPPAETQQIPRWGVHHPLPLGILTADKIVTVSPTYAQEIMTPAFGCGLEKFLQSRQQDVKGILNGLDEELWNPQTDTHIAQPFSAATISTRQKNKTELLKEFNLDPDPQRPLLILISRMDQQKGVDLAVKAARLIADEDWQMILLGTGDPTLEEDCRQLEKEYPDRVRAAIRFDASLSRRMYAGGDMLLMPSRYEPCGLAQMISMRYGCVPVARATGGLKDSIHQTLTMQHGTGFLFKPATESALARALRKALQIYQNPQLWQQIQLNGMAVNFSWATPALEYANLYQQLLKERNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XSB1</accession>
    <name>A0A0P6XSB1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RF_PROK_I domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_12650</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063384.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000027.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12650"/>
    <dbReference type="EnsemblBacteria" id="KPL75494">
        <property type="protein sequence ID" value="KPL75494"/>
        <property type="gene ID" value="ADN00_12650"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1222"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003747">
        <property type="term" value="F:translation release factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00472">
        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00745">
        <property type="entry name" value="RF_PROK_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RF_PROK_I" evidence="2">
        <location>
            <begin position="21"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS00745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL75494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="141" mass="16149" checksum="E88F432D1176873A" modified="2016-01-20" version="1">MLPITPTLAIDESELHFDFIRAAGPGGQNVNKVSSAVQLRFNIQESPSLPEDVRQRLLKLAGRRVNQAGELVIRAAQYRTQEQNRFDALDRLAELLRQAAEKPRARKATRPTVTAKARRLASKKQHGEIKRLRRYRPDDWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XSB4</accession>
    <name>A0A0P6XSB4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_07845</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000020">
        <property type="protein sequence ID" value="KPL78080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062436.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000020.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78080">
        <property type="protein sequence ID" value="KPL78080"/>
        <property type="gene ID" value="ADN00_07845"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2862"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="1"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="35"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL78080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="280" mass="31355" checksum="7B8839B8468B46BC" modified="2016-01-20" version="1">MEILSVQNLNKHYPKFDLKNVSFSLEQGYIMGFIGRNGAGKTTTIKSIMRLVHPDSGTVAVMGKNFADEEFVCKQQIGLVLGQVSYYPTKKLSVIADVTRRFYPEWDANAFAGYLKRFDLDPDKTVKELSDGMRVKFALAMALSHNARLLILDEPTSGLDPVSRDDLLELFQELIENSERSILFSTQITSDLDKCADYITYIKNGEIIASTSRDDLVNSYKIVKGTRAQLTETLLPQLIGCKKNDFGFTALLRTDNLPNADGLEIAPADLESIMIHIEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XU30</accession>
    <name>A0A0P6XU30_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_09585</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062781.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09585"/>
    <dbReference type="EnsemblBacteria" id="KPL76847">
        <property type="protein sequence ID" value="KPL76847"/>
        <property type="gene ID" value="ADN00_09585"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2372"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023204">
        <property type="entry name" value="SP1917_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014580">
        <property type="entry name" value="UCP033199"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09966">
        <property type="entry name" value="DUF2200"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF033199">
        <property type="entry name" value="UCP033199"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="119" mass="13717" checksum="A5ED74F1879CA4BC" modified="2016-01-20" version="1">MNDKSNHRIFGMKFADVYPLYVQKAERKNRTKAEVDQIICWLTGYDQAGLLQQIEQGNDFETFFAQAPAFHPNSSLIKGVVCGVRVEEIEDPLMQKIRYLDKLIDELAKGKAIEKILRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUV6</accession>
    <name>A0A0P6XUV6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_08880</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062643.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08880"/>
    <dbReference type="EnsemblBacteria" id="KPL77249">
        <property type="protein sequence ID" value="KPL77249"/>
        <property type="gene ID" value="ADN00_08880"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4009"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022694">
        <property type="entry name" value="3-OHacyl-CoA_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006176">
        <property type="entry name" value="3-OHacyl-CoA_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006108">
        <property type="entry name" value="3HC_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00725">
        <property type="entry name" value="3HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02737">
        <property type="entry name" value="3HCDH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000105">
        <property type="entry name" value="HCDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="3HCDH_N" evidence="3">
        <location>
            <begin position="8"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="3HCDH" evidence="2">
        <location>
            <begin position="190"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="1">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000105-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL77249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="305" mass="33664" checksum="7CD5C71119A82FBB" modified="2016-01-20" version="1">MRIEDLRTVLVIGAGTMGSQIGLQCAMHGFNVHLYDISAESVENGMRTIEGYLDGLIAQGVFPKEHKPVVLERIHPMTDAAAAAQADLVSESVPEDPALKGKVFAQFHQLCPAHTIFTTNTSSLLPSMYAEATGRPDRFAALHFHGYVWVSNVVDIMPHPGTSEETLDTLEAFARRIGQIPIRLGKEHYGYVLNSMLNALLRTATSLAANEVTSFENVDRAWMGVMKAPMGPFGILDQVGLETAYHINQYWATTLNDPELQKNADYLKAYVDRGLLGIKTGRGFYTYPNPKFMMPGFVEGDLDKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XW89</accession>
    <name>A0A0P6XW89_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA 2',3'-cyclic phosphodiesterase</fullName>
            <shortName evidence="2">RNA 2',3'-CPDase</shortName>
            <ecNumber evidence="2">3.1.4.58</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_01145</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Hydrolyzes RNA 2',3'-cyclic phosphodiester to an RNA 2'-phosphomonoester.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>a 3'-end 2',3'-cyclophospho-ribonucleotide-RNA + H2O = a 3'-end 2'-phospho-ribonucleotide-RNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:11828"/>
            <dbReference type="Rhea" id="RHEA-COMP:10464"/>
            <dbReference type="Rhea" id="RHEA-COMP:17353"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:83064"/>
            <dbReference type="ChEBI" id="CHEBI:173113"/>
            <dbReference type="EC" id="3.1.4.58"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the 2H phosphoesterase superfamily. ThpR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.58" evidence="2"/>
    <dbReference type="EMBL" id="LGCL01000003">
        <property type="protein sequence ID" value="KPL80829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061129.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01145"/>
    <dbReference type="EnsemblBacteria" id="KPL80829">
        <property type="protein sequence ID" value="KPL80829"/>
        <property type="gene ID" value="ADN00_01145"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1974"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004113">
        <property type="term" value="F:2',3'-cyclic-nucleotide 3'-phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008664">
        <property type="term" value="F:2'-5'-RNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01940">
        <property type="entry name" value="RNA_CPDase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009097">
        <property type="entry name" value="Cyclic_Pdiesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014051">
        <property type="entry name" value="Phosphoesterase_HXTX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004175">
        <property type="entry name" value="RNA_CPDase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35561">
        <property type="entry name" value="PTHR35561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02834">
        <property type="entry name" value="LigT_PEase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55144">
        <property type="entry name" value="SSF55144"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02258">
        <property type="entry name" value="2_5_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LigT_PEase" evidence="3">
        <location>
            <begin position="12"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="LigT_PEase" evidence="3">
        <location>
            <begin position="101"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="HXTX 1" evidence="2">
        <location>
            <begin position="45"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="HXTX 2" evidence="2">
        <location>
            <begin position="131"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="45"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01940"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL80829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="200" mass="22259" checksum="D8437C5B2B6D53D1" modified="2016-01-20" version="1">MEAIRSFIAIHLPEEIRVQLERIITQLKAGCPSASVRWVQSQNIHLTLKFLGDISPKNLKILTDLLESETAKHTIFEFNVSQLGAFPNPQRPSVIWVGVESNDALLHLQHRIDVETQRLGYASEARKFSPHLTLGRISRSASTADIRQIAETLAAVKIGSLGKVRAEKVHLFRSDLKPGGAVYTPLYVAPLSSGEYLQTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XWS0</accession>
    <name>A0A0P6XWS0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_08430</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062544.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77889">
        <property type="protein sequence ID" value="KPL77889"/>
        <property type="gene ID" value="ADN00_08430"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.688"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="198"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="301"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="111"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL77889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="333" mass="37907" checksum="DC2C3CF30267B644" modified="2016-01-20" version="1">MIEGGVVLKSLGEVGTTVLYVLIGTVILEAILYLVLMRWLKYHYALPFMLLAPAIVGLLVLVVYPLIWELNLSFGNMSLRRFKNWEYVGFTNYVRVFTEPVLKQRTLWPLLGQTVLWTLINVVFHVVGGMILALLLNREMKGRGLYRMIIIIPWAIPQIIAVLAWRGEFNFEYGFLNVILTRMGLAPIQWLTTPGPNFAAMCITNIWLGIPFMMVILLGGLQSISGDFYEAAEIDGANGWQQFWNITIPLMQPVMAPAIILGTVWTFNNFNVPFFINQFELESSDILVTALFRAAFQYNRYGFSAAFAFVIFIFLLVYSIFYLRVTGALKGVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XWT9</accession>
    <name>A0A0P6XWT9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01935</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000007">
        <property type="protein sequence ID" value="KPL80055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061278.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000007.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80055">
        <property type="protein sequence ID" value="KPL80055"/>
        <property type="gene ID" value="ADN00_01935"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="222"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="253"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="302"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="333"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="401"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="433"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="464"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="497"/>
            <end position="514"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="671" mass="74195" checksum="02E502B6B57A4DB3" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XXE9</accession>
    <name>A0A0P6XXE9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01665</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061222.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80576">
        <property type="protein sequence ID" value="KPL80576"/>
        <property type="gene ID" value="ADN00_01665"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039968">
        <property type="entry name" value="YghO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41368">
        <property type="entry name" value="PTHR41368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="203"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="377" mass="43222" checksum="C2248F2EF2E0F9CF" modified="2016-01-20" version="1">MPTITIKPAQTARERRIFLTLPWKIYRRDPLWVPPLLPDRRKAIDPRRGVFFRRGGEAEFFIAWRGGQPVGTICCAVDHPSNRETGLQESVFGFFECIDDGDVARALFDHATAWARQRGLSSITGPFHLDYEDSYGVLIEGRDRPPAILCGHTPAYYQTFFESYGFTPSRGDNIAFALDLNKPSPALDRLAQGAQRAREQGRFTVRAARFAEWEAEIDRVHPLINAALAHLPDHRPWPREALQESFAPFKQIADPELILFVEEQGKVVGFFPGVPNLNEALIHANGLRYPWNYLQLAWWMRQPVRCLAVKSVLVYPEYWSSGASLLLFDEMLSRARARGYWWADLSLTSTDNPKTPMLAERLGAKIYKRYRVYRLEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XY62</accession>
    <name>A0A0P6XY62_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase</fullName>
            <ecNumber evidence="2">2.7.6.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_00625</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 7,8-dihydroneopterin triphosphate: step 4/4.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.3" evidence="2"/>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00625"/>
    <dbReference type="EnsemblBacteria" id="KPL81070">
        <property type="protein sequence ID" value="KPL81070"/>
        <property type="gene ID" value="ADN00_00625"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3520"/>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003848">
        <property type="term" value="F:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00483">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000550">
        <property type="entry name" value="Hppk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035907">
        <property type="entry name" value="Hppk_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01288">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55083">
        <property type="entry name" value="SSF55083"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01498">
        <property type="entry name" value="folK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00794">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HPPK" evidence="8">
        <location>
            <begin position="94"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL81070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="173" mass="19652" checksum="CD67C4E0B2B997B1" modified="2016-01-20" version="1">MNNKYSSINQAFLLLGSNIEPEKNLPKAVKLLSQYGHIRKVSSVWQSAAAGFTEQPDFLNAAMLLETDLSPDALRRQAIHTVEDSLERIRTENKNGPRTIDIDIILFNRDVLNLGTRHIPDPDLQEQLFVAMPLAEIAPDYLHPELNQTLEEIAHQLYPKAEAIFRRDDVKLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XY71</accession>
    <name>A0A0P6XY71_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_00750</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061038.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00750"/>
    <dbReference type="EnsemblBacteria" id="KPL81088">
        <property type="protein sequence ID" value="KPL81088"/>
        <property type="gene ID" value="ADN00_00750"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3548"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="7"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="82"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL81088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="219" mass="24277" checksum="05D2C910FE4F5CA9" modified="2016-01-20" version="1">MLVGNRMSHPVITVYPDTLLQDALDLMHKEKIRRLPVVDHRGKLIGIVSERVLLKAYPSDATSLSVWEMRSIMKKVTIEEFLTREVITVTEDTPLEEAARIMTDNHISGLPVMRDDKLVGFITETDLFKIFLEVMGARDPGVRITAEVTRQPGVLASITKAIHELGGDIMALGTFMGESADTGEILVKVDCVDPKQAVEAIKPFVVKVIDVRGVSSKRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XY88</accession>
    <name>A0A0P6XY88_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein-export membrane protein SecF</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">secF</name>
        <name evidence="10" type="ORF">ADN00_00975</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Forms a complex with SecD. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the SecD/SecF family. SecF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061081.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00975"/>
    <dbReference type="EnsemblBacteria" id="KPL81125">
        <property type="protein sequence ID" value="KPL81125"/>
        <property type="gene ID" value="ADN00_00975"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3594"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015450">
        <property type="term" value="F:protein-transporting ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043952">
        <property type="term" value="P:protein transport by the Sec complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01464_B">
        <property type="entry name" value="SecF_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022813">
        <property type="entry name" value="SecD/SecF_arch_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022645">
        <property type="entry name" value="SecD/SecF_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022646">
        <property type="entry name" value="SecD/SecF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005665">
        <property type="entry name" value="SecF_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30081">
        <property type="entry name" value="PTHR30081"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07549">
        <property type="entry name" value="Sec_GG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02355">
        <property type="entry name" value="SecD_SecF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01755">
        <property type="entry name" value="SECFTRNLCASE"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00966">
        <property type="entry name" value="3a0501s07"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="9"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="128"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="154"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="244"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="268"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL81125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="308" mass="33428" checksum="D024128C5AC5B8D0" modified="2016-01-20" version="1">MLDILGKRYLYFALSLVLIVPGLLILLLGGGMNMSIDFTGGSLLEVRFDSGTAPQPADVIALYNEMGITDVTVKTSGTDALLIQSTFIDDETRIALMDKMETQFNDTITLLQYDSVGPSIGQEVTSRAGLAIAVAALGVIIYISLAFRGVANAFRYGVCAILAMIHDVLIVVSLAAIGGKFFGWQFDSLTLTALLTVIGFSVQDKIVVFDRIRENSAIFRKISFETLANHSIIQSLGRSINTQLMTSEFMLLALALFGGVTLREFAIILLVGLLSGTYSSIFIAAPTLVIWENKEWKTWFKKGNTSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XYE0</accession>
    <name>A0A0P6XYE0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ASCH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_14065</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14065"/>
    <dbReference type="EnsemblBacteria" id="KPL74151">
        <property type="protein sequence ID" value="KPL74151"/>
        <property type="gene ID" value="ADN00_14065"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1913"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06553">
        <property type="entry name" value="ASCH_Ef3133_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007374">
        <property type="entry name" value="ASCH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009326">
        <property type="entry name" value="DUF984"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39203">
        <property type="entry name" value="PTHR39203"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04266">
        <property type="entry name" value="ASCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF021320">
        <property type="entry name" value="DUF984"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01022">
        <property type="entry name" value="ASCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ASCH" evidence="1">
        <location>
            <begin position="14"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="143" mass="16154" checksum="A8EB53366E61E9AC" modified="2016-01-20" version="1">MPAGAPRPQTFQSWAFGHDADVASRLAALVRKGVKTATSGLLWSYEAEQEDTPEVGGYSVITDWEGRPLCIIQTLEVIVRPFHEVGADIAWEEGEGDRSLEYWREVHWEFFAEECAQLGRAPQDDMPVVSERFRLVFDQSPDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y0J3</accession>
    <name>A0A0P6Y0J3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">(4Fe-4S)-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_06280</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062109.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06280"/>
    <dbReference type="EnsemblBacteria" id="KPL78822">
        <property type="protein sequence ID" value="KPL78822"/>
        <property type="gene ID" value="ADN00_06280"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1758"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002586">
        <property type="entry name" value="CobQ/CobB/MinD/ParA_Nub-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01656">
        <property type="entry name" value="CbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00037">
        <property type="entry name" value="Fer4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="60"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="89"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL78822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="288" mass="31053" checksum="DECDFE76ED73A502" modified="2016-01-20" version="1">MRIAVASGKGGTGKTTIATSLALSLSAERETWYVDCDVEAPNGHLFLRPNFTYSTQAVIKIPQIQVDQCTMCGKCVEVCQFHALANVVKSIMVFPQLCHGCGSCTLNCPVQAISEVDNPIGMLESGFTAEGIQFRRGVLSISEPMPTPVIRQLKRMDQAPDDALVILDSPPGASCSVVETLRGADYALLVTEPTPFGLHDLKQMIGIVQDMNIPAGIVVNRDGIGSPQVEAYLLELSLPILLRVPFDKKIASGIAAGESLMAVRPEYRQDFVELYQAICDQVKAGKPC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y2C0</accession>
    <name>A0A0P6Y2C0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FtsX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_04165</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061702.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79078">
        <property type="protein sequence ID" value="KPL79078"/>
        <property type="gene ID" value="ADN00_04165"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="17"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="269"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="306"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="349"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="293"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL79078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="385" mass="41368" checksum="FC2CA674FE157B59" modified="2016-01-20" version="1">MGLYLAIKEIWRNRTRFLLFSLVIALITTLVLFIAALAVGLANANKEYLDKLNTDLLAFQDNVELQITTSQIGWSKLNDIRRVDGVVDIGAIGYSRATLVFEDGREPVDVSLIGVEAGRPGSPSVIDGRALRTTRGNEVVIDENAVRQAGLAIGDQIVIKVIQGTKEEFYALRVVGTAEAQQYLYAPSVFLPFQTWERVRPQAARGGTPGREQAANMVAIRVQNGLNLQSAASRIQSQVSGLQVVDKETAIQAIPGYSVQQSTLNTQRSFTLLIGLLVIGGFFQIQTLQKVPQIGVLKAIGADNKVIAVSVVSQISIVTLIGVAIGALVTFLFSIFLPSAVPIIFEPRAIIFQILGLLAIGPLGGLVAVRLATRIEPLTALGVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y382</accession>
    <name>A0A0P6Y382_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_12105</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063276.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12105"/>
    <dbReference type="EnsemblBacteria" id="KPL76080">
        <property type="protein sequence ID" value="KPL76080"/>
        <property type="gene ID" value="ADN00_12105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="211"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="259"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="292"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="383"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="413"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="438"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="471"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="561" mass="61025" checksum="9725BACF8ED8B7B3" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y3D8</accession>
    <name>A0A0P6Y3D8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">ATP synthase subunit b</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">ATP synthase F(0) sector subunit b</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">ATPase subunit I</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">F-type ATPase subunit b</fullName>
            <shortName evidence="11">F-ATPase subunit b</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">atpF</name>
        <name evidence="13" type="ORF">ADN00_12420</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Component of the F(0) channel, it forms part of the peripheral stalk, linking F(1) to F(0).</text>
    </comment>
    <comment type="function">
        <text evidence="10 11">F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">F-type ATPases have 2 components, F(1) - the catalytic core - and F(0) - the membrane proton channel. F(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). F(0) has three main subunits: a(1), b(2) and c(10-14). The alpha and beta chains form an alternating ring which encloses part of the gamma chain. F(1) is attached to F(0) by a central stalk formed by the gamma and epsilon chains, while a peripheral stalk is formed by the delta and b chains.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cell membrane</location>
            <topology evidence="11">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11 12">Belongs to the ATPase B chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063334.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12420"/>
    <dbReference type="EnsemblBacteria" id="KPL76135">
        <property type="protein sequence ID" value="KPL76135"/>
        <property type="gene ID" value="ADN00_12420"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3965"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045263">
        <property type="term" value="C:proton-transporting ATP synthase complex, coupling factor F(o)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01398">
        <property type="entry name" value="ATP_synth_b_bprime"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002146">
        <property type="entry name" value="ATP_synth_b/b'su_bac/chlpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005864">
        <property type="entry name" value="ATP_synth_F0_bsu_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020781">
        <property type="entry name" value="ATPase_OSCP/d_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000711">
        <property type="entry name" value="ATPase_OSCP/dsu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00430">
        <property type="entry name" value="ATP-synt_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00213">
        <property type="entry name" value="OSCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00125">
        <property type="entry name" value="ATPASEDELTA"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01144">
        <property type="entry name" value="ATP_synt_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01145">
        <property type="entry name" value="ATP_synt_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00389">
        <property type="entry name" value="ATPASE_DELTA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="11" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 11 12" id="KW-0138">CF(0)</keyword>
    <keyword evidence="5 11 12" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="7 11 12" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 11" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 11 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="6"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KPL76135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="247" mass="27845" checksum="623E90A57E1DB9FD" modified="2016-01-20" version="1">MDQLGLNLGYILVQILNFGIIMVVVYAWVLKPIFRVIQNRQDALAQSMNDSRIASEARARAEEEAKKIISEAHMKADKIVQEANERAERNALDIRQTAAAEAQAERDSMLKEMERERDDVFFKLRHQVSVLAIAAAHRLIQESLIQDEARQHALLKEFFSGIRDKKLVVLDGRSEKGSFVHVISALPLEPDEVEIIENNLKEQIQGEIKVQYEVDPSILGGVIIKIGDHVINGSVAGQLEDLYRGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y5G7</accession>
    <name>A0A0P6Y5G7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Bmp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_01520</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BMP lipoprotein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061196.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80550">
        <property type="protein sequence ID" value="KPL80550"/>
        <property type="gene ID" value="ADN00_01520"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003760">
        <property type="entry name" value="PnrA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02608">
        <property type="entry name" value="Bmp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133382" description="Bmp domain-containing protein" evidence="3">
        <location>
            <begin position="24"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="Bmp" evidence="4">
        <location>
            <begin position="62"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL80550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="364" mass="37846" checksum="545582E96DEE328C" modified="2016-01-20" version="1">MKSKLFVGVVLMVLLAVMVAGCAAPTPEVIEKEVTRVVEGEKVVEEVVVTATPAPEVKETFRVAVVMPSSITDMAFSQSFYEGLLKVQEEMGGPQAMEIAYSEGMFNVPDAAAALRDYASEGYDLVVAHGSQYGTSLSQVAPDFPDTSFAWGTSIDTFQAQGIENVFAYQAEAQEGGYVLGTIAALMSESGVLGVSGPVEAGDAKLYVDGFAAGAKSANPNVNVQISYTGSFSDVSLMATAAETHMSAGADMLTGSSQSVVGAIGIAKDNGGKWFGTQWDQTALAPDTVVASQVYDWTGIIKDMIESHNAGVMGGKAYTLTFKNGGLVIAYNPAIEVPAEIKAAADAAIQGIMDGTIDPLAVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y5T9</accession>
    <name>A0A0P6Y5T9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH tetR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_10315</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062920.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76967">
        <property type="protein sequence ID" value="KPL76967"/>
        <property type="gene ID" value="ADN00_10315"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="10"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL76967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="191" mass="21451" checksum="A8E81592022681C1" modified="2016-01-20" version="1">MARRIHSQGEETRQSILAAASRLFVENGVGSTSLKDIAREAQISPGTLFYYYSSKSELIFEVTDQHFDRVTRQLLDWARTSDLQADPAAILEVVLKTIVGDQVRGKLHHYLIEAALSSDAAVRERFLQKYREWRAMIEDGIAPFVADDEQRRIAALIFLSTLDGLVMQAILGVEELPLEKIADRFAGGMLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y948</accession>
    <name>A0A0P6Y948_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA small subunit methyltransferase H</fullName>
            <ecNumber evidence="6">2.1.1.199</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">16S rRNA m(4)C1402 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">rRNA (cytosine-N(4)-)-methyltransferase RsmH</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rsmH</name>
        <name evidence="7" type="ORF">ADN00_07355</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Specifically methylates the N4 position of cytidine in position 1402 (C1402) of 16S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>cytidine(1402) in 16S rRNA + S-adenosyl-L-methionine = H(+) + N(4)-methylcytidine(1402) in 16S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42928"/>
            <dbReference type="Rhea" id="RHEA-COMP:10286"/>
            <dbReference type="Rhea" id="RHEA-COMP:10287"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74506"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.199"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the methyltransferase superfamily. RsmH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.199" evidence="6"/>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062334.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07355"/>
    <dbReference type="EnsemblBacteria" id="KPL78275">
        <property type="protein sequence ID" value="KPL78275"/>
        <property type="gene ID" value="ADN00_07355"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3292"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071424">
        <property type="term" value="F:rRNA (cytosine-N4-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01007">
        <property type="entry name" value="16SrRNA_methyltr_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002903">
        <property type="entry name" value="RsmH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023397">
        <property type="entry name" value="SAM-dep_MeTrfase_MraW_recog"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11265">
        <property type="entry name" value="PTHR11265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01795">
        <property type="entry name" value="Methyltransf_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004486">
        <property type="entry name" value="MraW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81799">
        <property type="entry name" value="SSF81799"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00006">
        <property type="entry name" value="TIGR00006"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6 7" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="6">
        <location>
            <begin position="40"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL78275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="313" mass="34434" checksum="83CC48AECF26EEFA" modified="2016-01-20" version="1">MNAPIPGDSSPHLPVLYQEVIQALQPVNRGRYLDATLGAGGHSWGILTASSPAGEVLGLDLDPQALAIASQRLSVFGSRAHLVQASYVTLLDQIHALGWQTVDGIVIDLGVSSMQVDTPERGFSFLADGPLDMRFSPTQPATAADLVNHLSEQDLSEIIWKYGEERHARRVARAIVENRPFSTTAQLAALIAKTLKGQHERIHPATRTFQALRIAVNQELQALEDFLPRALQALHPGGRLAVISFHSLEDRIVKQVFKRESQDCICPPEQIICTCGHKAQIRLITRRPLMAGEDEIQNNPRARSARLRIAEKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y977</accession>
    <name>A0A0P6Y977_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_07540</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062369.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78302">
        <property type="protein sequence ID" value="KPL78302"/>
        <property type="gene ID" value="ADN00_07540"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="99" mass="11294" checksum="7984BB519B11BD39" modified="2016-01-20" version="1">MYFGVFLIFLLFPIGIISIVNPLYIAVSIMKSIKIFFYQVTKEKFLTPRNRKMFELLDSSPKSFAEKYPLLMVEVRIGGIIGICMALGLTCMLVATIFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YAI4</accession>
    <name>A0A0P6YAI4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DhaK domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05910</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05910"/>
    <dbReference type="EnsemblBacteria" id="KPL78878">
        <property type="protein sequence ID" value="KPL78878"/>
        <property type="gene ID" value="ADN00_05910"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004371">
        <property type="term" value="F:glycerone kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006071">
        <property type="term" value="P:glycerol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004006">
        <property type="entry name" value="DhaK_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02733">
        <property type="entry name" value="Dak1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51481">
        <property type="entry name" value="DHAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DhaK" evidence="1">
        <location>
            <begin position="12"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="338" mass="36247" checksum="5A1C51855CE4A863" modified="2016-01-20" version="1">MKFQPSGKFINHPETMISEENEGLALAYPEILTYLPQGFLVRAYKKEAGKVGLAIGHGGGHTPSMGGLVGKGLLDSDVYGPIFTCASGVKIAHAIELADQSAGVALLISNHAGDVLNARLGMRRAEQLGIQVEPVYLGDDIATAPRAEFEKRRGLGGLLFALKIGGAAAENGKSLAEVAGLMRKTNQRTATLAVAVRPPTHPATGIPLFEMPIGQVEIGTGVHGEVGVYRGDLLPADEIIDLILPKLVDDLSDFHEKQFLIFLNGSGGTSRMELNILYRRVHHSLQNQGFEIAGSLVDSLFTTQEMGGFSLSLCAVDKELLELWNENASAACFRWPMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YEQ5</accession>
    <name>A0A0P6YEQ5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Histidine kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01735</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061235.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01735"/>
    <dbReference type="EnsemblBacteria" id="KPL80588">
        <property type="protein sequence ID" value="KPL80588"/>
        <property type="gene ID" value="ADN00_01735"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13492">
        <property type="entry name" value="GAF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Histidine kinase" evidence="1">
        <location>
            <begin position="360"/>
            <end position="557"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="559" mass="61847" checksum="B9CB8A8A5AE89FCD" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GKN0</accession>
    <name>A0A0N8GKN0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">dCTP deaminase</fullName>
            <ecNumber evidence="3">3.5.4.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Deoxycytidine triphosphate deaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">dcd</name>
        <name evidence="5" type="ORF">ADN00_19180</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the deamination of dCTP to dUTP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>dCTP + H(+) + H2O = dUTP + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:22680"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:61481"/>
            <dbReference type="ChEBI" id="CHEBI:61555"/>
            <dbReference type="EC" id="3.5.4.13"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Pyrimidine metabolism; dUMP biosynthesis; dUMP from dCTP (dUTP route): step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the dCTP deaminase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.13" evidence="3"/>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064649.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_19180"/>
    <dbReference type="EnsemblBacteria" id="KPL70154">
        <property type="protein sequence ID" value="KPL70154"/>
        <property type="gene ID" value="ADN00_19180"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3148"/>
    <dbReference type="UniPathway" id="UPA00610">
        <property type="reaction ID" value="UER00665"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008829">
        <property type="term" value="F:dCTP deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006226">
        <property type="term" value="P:dUMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006229">
        <property type="term" value="P:dUTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07557">
        <property type="entry name" value="trimeric_dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00146">
        <property type="entry name" value="dCTP_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011962">
        <property type="entry name" value="dCTP_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029054">
        <property type="entry name" value="dUTPase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036157">
        <property type="entry name" value="dUTPase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033704">
        <property type="entry name" value="dUTPase_trimeric"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00692">
        <property type="entry name" value="dUTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51283">
        <property type="entry name" value="SSF51283"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02274">
        <property type="entry name" value="dCTP_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 3" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="dUTPase" evidence="4">
        <location>
            <begin position="78"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="133"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="107"/>
            <end position="112"/>
        </location>
        <ligand>
            <name>dCTP</name>
            <dbReference type="ChEBI" id="CHEBI:61481"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="131"/>
            <end position="133"/>
        </location>
        <ligand>
            <name>dCTP</name>
            <dbReference type="ChEBI" id="CHEBI:61481"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>dCTP</name>
            <dbReference type="ChEBI" id="CHEBI:61481"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>dCTP</name>
            <dbReference type="ChEBI" id="CHEBI:61481"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>dCTP</name>
            <dbReference type="ChEBI" id="CHEBI:61481"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>dCTP</name>
            <dbReference type="ChEBI" id="CHEBI:61481"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL70154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="184" mass="20781" checksum="26AAF0D83F90435C" modified="2016-01-20" version="1">MGLKPDHWIRKMSLEHGMIEPFVDHQVRNGVVSYGVSSYGYDVRVANEFKIFTNVFSATVDPKNFDPRSMIDFVGDVCIIPPNSFALAKTVEYFRIPRSVLTVCLGKSTYARCGIIVNVTPFEPQWEGFVTLEISNTTPLPAKIYANEGIAQVLFFEADEECEISYADKKGKYQNQQTILLPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GKX3</accession>
    <name>A0A0N8GKX3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_17845</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000043">
        <property type="protein sequence ID" value="KPL70898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064399.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000043.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70898">
        <property type="protein sequence ID" value="KPL70898"/>
        <property type="gene ID" value="ADN00_17845"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="121" mass="13450" checksum="1CB6E5517440F7F5" modified="2016-01-20" version="1">MRSARIFWFMVSLVIGLAGGLVYGWVVRPLNYTDVSARQLRSDYRTDYVLMTAEVFAKDGDPAKAAEQLSFLGNEPVIRYVQQAIIEGSEMGYARADLDLMGSLAAALQNWMPLQEEGVTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GL43</accession>
    <name>A0A0N8GL43_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_17400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71458.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL71458">
        <property type="protein sequence ID" value="KPL71458"/>
        <property type="gene ID" value="ADN00_17400"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006025787" evidence="2">
        <location>
            <begin position="23"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="28"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL71458.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="96" mass="10963" checksum="F5DFCBA5F89A0ED9" modified="2016-01-20" version="1">MSTIFYKKVFFLRMIRGLSAHAADAEGGASRQNEKGDQNHEHHDTGFRSDFLEHWMTSLKLIDLVTTLISLRIGGFKTGFKTVSKWTNFRNSSKLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GLV7</accession>
    <name>A0A0N8GLV7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Pyr_redox_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_14610</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000035">
        <property type="protein sequence ID" value="KPL73570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14610"/>
    <dbReference type="EnsemblBacteria" id="KPL73570">
        <property type="protein sequence ID" value="KPL73570"/>
        <property type="gene ID" value="ADN00_14610"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="1">
        <location>
            <begin position="15"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL73570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="458" mass="50170" checksum="0D838634A1B37139" modified="2016-01-20" version="1">MEESLNQPNTPSHLVAVVGAGPAGLYVAKELSKNNEVVLINRDIKPGGLAEYGIYPDKTKIRQGLKTQFREILSRPNVHYFGNLNISCQGDLKLKELRQMGFQAVVVTVGAQHARSLGIPGEELQGVYHAKDLVYHYSGLPPYSQQPFPIGRRVAVIGMGNVMLDITRYLTRVVKVDEVIAIARRGPGEIKFDKAELEGVAASLDVDAFEKELRSHRELMLSLGQNPEEIRGMVLSAVEKAEPAVSNSRFSIRFLLSPTCVIGDGSNHVCGLELERNTLFNQSDEYVSAKGTGEREMLPVDTIIFAIGNRVESGLGLPTRGSSFISNPNPRFPVHDISYEILDENGNLMEDIFVAGWARQASTGLVGLARRDSINAARAVSQYLQTLPPHADIPGALQAFNARAVSLQHPVITNADLRRLEDVEDQLAAQKGVEEFKFTTNEEMLAAIGLSETQTQMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMF8</accession>
    <name>A0A0N8GMF8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SpoU_sub_bind domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000030">
        <property type="protein sequence ID" value="KPL75178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063483.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000030.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13160"/>
    <dbReference type="EnsemblBacteria" id="KPL75178">
        <property type="protein sequence ID" value="KPL75178"/>
        <property type="gene ID" value="ADN00_13160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="L30e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013123">
        <property type="entry name" value="SpoU_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08032">
        <property type="entry name" value="SpoU_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00967">
        <property type="entry name" value="SpoU_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="SSF55315"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SpoU_sub_bind" evidence="1">
        <location>
            <begin position="30"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL75178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="262" mass="28090" checksum="755B46C71ED9455C" modified="2016-01-20" version="1">MITSSQNAKIKLARALTARSKDRQKTGAFIVEGVRLAEEALAAAWQPQMVLFSAQLSARGLQIVEAYRSSGVEVEEASPEVLASLSDTETPQGIYAIFARRDLPLPSQPDFILIADQVRDPGNLGTLIRTAAAAAVQALIVPPGTTDPFAPKVLRSAMGAHFRLPILELSWPQIVTRFKADARPSLRFLIAEAQGGDSCWQARLDQPVVLIVGSEAEGASPEARQAADGLIHIPMPGQSESLNAAVAGSILCFEVVRQRSHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMK0</accession>
    <name>A0A0N8GMK0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Pyruvate formate lyase-activating protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_12770</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="6">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063407.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000027.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12770"/>
    <dbReference type="EnsemblBacteria" id="KPL75514">
        <property type="protein sequence ID" value="KPL75514"/>
        <property type="gene ID" value="ADN00_12770"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027596">
        <property type="entry name" value="AmmeMemoSam_rS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034457">
        <property type="entry name" value="Organic_radical-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016431">
        <property type="entry name" value="Pyrv-formate_lyase-activ_prd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30352">
        <property type="entry name" value="PTHR30352"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004869">
        <property type="entry name" value="PflX_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01101">
        <property type="entry name" value="Uncharacterised_Radical_SAM_Su"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04337">
        <property type="entry name" value="AmmeMemoSam_rS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="5 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="7">
        <location>
            <begin position="77"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="96"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR004869-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL75514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="371" mass="41275" checksum="1A311D378477FA69" modified="2016-01-20" version="1">MAALQEVIDQLTAPGELFTREEDQRVRCTACAHRCLLKPGQRGICRVRYNQDGELRVPFGYVLSAQVDPIEKKPFAHLLPGSDALTFGMVGCNFHCDFCQNWVSAQALREPSARIGAEHLQRVTPRQLVNFALRSGAQAVVSSYNEPLITSEWAAAIFKEAHQAGLKTAYVSNGFATPEVLAYLQPHLDAYKIDLKCMREDGYRELGGHLQDVLDTIRGALDLGLWVEVVTLVIPGFNDSSEELWELSRFLVSVSKDIPWHVTAFHPDYQRLETESTPAATLQRAAEIGEEAGLRYVYAGNLPGRVGPLENTYCPHCRARLITRRGYTVQEYHITAAGTCPQCGAPIPGVWTDKPEQVRLGGWGLPRRAQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMR0</accession>
    <name>A0A0N8GMR0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_11550</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL75994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063171.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL75994">
        <property type="protein sequence ID" value="KPL75994"/>
        <property type="gene ID" value="ADN00_11550"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL75994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="202" mass="23424" checksum="6D29050BCBB69027" modified="2016-01-20" version="1">MKKTGVILFIILIWIPSMIGARLLSAFYCYTLLLPPKDPEIPEIIASRIGIQAEWDAIQDYLSYGSIKVGMHRNEVLGIIDQIGPYRIELLYPFDNSSEDFNVDLEPFYEENFYFIDDLTNRELGVWYFDYDFGILTSFYREDLYLDIGEGIDEEDKSLKVKTILDPWLDRFHRGVLCHSCTGMLSGKIYTATRHRNCSGDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMS3</accession>
    <name>A0A0N8GMS3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">LytR_cpsA_psr domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_12210</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LytR/CpsA/Psr (LCP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063295.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12210"/>
    <dbReference type="EnsemblBacteria" id="KPL76098">
        <property type="protein sequence ID" value="KPL76098"/>
        <property type="gene ID" value="ADN00_12210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004474">
        <property type="entry name" value="LytR_CpsA_psr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03816">
        <property type="entry name" value="LytR_cpsA_psr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00350">
        <property type="entry name" value="lytR_cpsA_psr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006025807" description="LytR_cpsA_psr domain-containing protein" evidence="3">
        <location>
            <begin position="22"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="LytR_cpsA_psr" evidence="4">
        <location>
            <begin position="109"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="48"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="48"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL76098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="344" mass="37852" checksum="E3F7EE72D690199D" modified="2016-01-20" version="1">MIIMKKLTLLACISFLLASCAMPLATQGGIVAKPISYVFATPNPNATTTPTPFQPLPATATPTLAPATPTPEFTSTPEVRYWWTGLKRPEGQKLILLLGSDWRYGGGFRTDVIMLIALNPKENTANIVSFPRDLYVSIPGVGQNRLNVAHAYGGFDLMAQTLELNFGVRPDYYIMTNFDGFVSIINNVGGINVNAYYNLTDKCDLPQASYDGYCSVGPGTVYMDGKTALWYVRSRYSTSDFDRTRREQEVIYALFAKLISLNAISRIPELYNIYQSSVETNINLDTVVSLAPMAPILLEKDAIRRFYIGPQQVSSYIVPESGAAVLLPNDEAIGAVLKQAIFEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMX6</accession>
    <name>A0A0N8GMX6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NB-ARC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_11165</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063094.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11165"/>
    <dbReference type="EnsemblBacteria" id="KPL76522">
        <property type="protein sequence ID" value="KPL76522"/>
        <property type="gene ID" value="ADN00_11165"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NB-ARC" evidence="1">
        <location>
            <begin position="166"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="1044" mass="115185" checksum="4F358A729FABE649" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNK1</accession>
    <name>A0A0N8GNK1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Flavodoxin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_07675</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the WrbA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062393.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07675"/>
    <dbReference type="EnsemblBacteria" id="KPL78322">
        <property type="protein sequence ID" value="KPL78322"/>
        <property type="gene ID" value="ADN00_07675"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3365"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003955">
        <property type="term" value="F:NAD(P)H dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010089">
        <property type="entry name" value="Flavoprotein_WrbA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01755">
        <property type="entry name" value="flav_wrbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="2">
        <location>
            <begin position="6"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="202" mass="21556" checksum="1780763387F9CAF1" modified="2016-01-20" version="1">MSKVKLSIIYYSSTGANYQMALAAKQAAEDAGAEVRLRKVQELAPQVAIDSNPAWKQYVEDSNDVQVASLDDLDWADAYLFGAPTRFGNVASQMKQFIDTTGPLWAQGKLSNKAVAAFTSAQNPHGGQESTLLALYNTFYHWGSIIVPPGYTDAAVFAAGGNPYGVSTSANGEPVSAAALDAVRYMTRRLVKVAGWIKAGQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNT7</accession>
    <name>A0A0N8GNT7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_03720</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79010">
        <property type="protein sequence ID" value="KPL79010"/>
        <property type="gene ID" value="ADN00_03720"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="59" mass="6735" checksum="A465107720DC587E" modified="2016-01-20" version="1">MILNVGYGFIWREDYEFPWLSSVFYAFLFFKTARPTSPLFALRWALIGFASGTISMGSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNV4</accession>
    <name>A0A0N8GNV4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Serine--tRNA ligase</fullName>
            <ecNumber evidence="7">6.1.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Seryl-tRNA synthetase</fullName>
            <shortName evidence="7">SerRS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Seryl-tRNA(Ser/Sec) synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">serS</name>
        <name evidence="10" type="ORF">ADN00_04630</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the attachment of serine to tRNA(Ser). Is also able to aminoacylate tRNA(Sec) with serine, to form the misacylated tRNA L-seryl-tRNA(Sec), which will be further converted into selenocysteinyl-tRNA(Sec).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + L-serine + tRNA(Sec) = AMP + diphosphate + H(+) + L-seryl-tRNA(Sec)</text>
            <dbReference type="Rhea" id="RHEA:42580"/>
            <dbReference type="Rhea" id="RHEA-COMP:9742"/>
            <dbReference type="Rhea" id="RHEA-COMP:10128"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78533"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + L-serine + tRNA(Ser) = AMP + diphosphate + H(+) + L-seryl-tRNA(Ser)</text>
            <dbReference type="Rhea" id="RHEA:12292"/>
            <dbReference type="Rhea" id="RHEA-COMP:9669"/>
            <dbReference type="Rhea" id="RHEA-COMP:9703"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78533"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Aminoacyl-tRNA biosynthesis; selenocysteinyl-tRNA(Sec) biosynthesis; L-seryl-tRNA(Sec) from L-serine and tRNA(Sec): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer. The tRNA molecule binds across the dimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="7">Consists of two distinct domains, a catalytic core and a N-terminal extension that is involved in tRNA binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the class-II aminoacyl-tRNA synthetase family. Type-1 seryl-tRNA synthetase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.11" evidence="7"/>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061787.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04630"/>
    <dbReference type="EnsemblBacteria" id="KPL79146">
        <property type="protein sequence ID" value="KPL79146"/>
        <property type="gene ID" value="ADN00_04630"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.287"/>
    <dbReference type="UniPathway" id="UPA00906">
        <property type="reaction ID" value="UER00895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004828">
        <property type="term" value="F:serine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016260">
        <property type="term" value="P:selenocysteine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097056">
        <property type="term" value="P:selenocysteinyl-tRNA(Sec) biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006434">
        <property type="term" value="P:seryl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00770">
        <property type="entry name" value="SerRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00176">
        <property type="entry name" value="Ser_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002317">
        <property type="entry name" value="Ser-tRNA-ligase_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015866">
        <property type="entry name" value="Ser-tRNA-synth_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042103">
        <property type="entry name" value="SerRS_1_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033729">
        <property type="entry name" value="SerRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43697">
        <property type="entry name" value="PTHR43697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02403">
        <property type="entry name" value="Seryl_tRNA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001529">
        <property type="entry name" value="Ser-tRNA-synth_IIa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00981">
        <property type="entry name" value="TRNASYNTHSER"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="SSF46589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00414">
        <property type="entry name" value="serS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="9">
        <location>
            <begin position="163"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Serine binding" evidence="7">
        <location>
            <begin position="229"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="31"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="260"/>
            <end position="262"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="347"/>
            <end position="350"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="383"/>
        </location>
        <ligand>
            <name>L-serine</name>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL79146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="425" mass="48234" checksum="8041F67EAC66BBE0" modified="2016-01-20" version="1">MLDIALIRENPDVVREALRKRQMDTAAVDQVAELDVKRRGLLTEVETLKAERNRVSKEIGRMKEKDEREAKIAEMREVGDRISALDEQVRQVDVDLQALVAGIPNLPDARTPLGKDESENVVVRQHGEKPQFNFEPKPHWDLGTELDIIDFEEGVKITGSRFYVLNGAGARLQRALIAWMLDLHIRQGYKEKYTPFMVKGDTLYASGQLPKFADNLYRDHEEDFWMVPTAEVPLTGIHIDDVFTEDQLPRRYTAYTPCFRREKMSAGRDVRGIKRGHQFDKVEMYIYCTPEQSDAELDKMLADAEQTCRDLGLTYRVVQLCTGDLGFNAAVTYDVEVWAPGCGEWLEVSSVSKVGDFQPRRANIKYRPADGSKTRLVHTLNGSGLGLPRTLIAVLENYQQPDGSIVVPEVLRPWMGGVDVIRAEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNX7</accession>
    <name>A0A0N8GNX7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_03110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000014">
        <property type="protein sequence ID" value="KPL79330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061499.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000014.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79330">
        <property type="protein sequence ID" value="KPL79330"/>
        <property type="gene ID" value="ADN00_03110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="62" mass="6976" checksum="F49263E9545E6773" modified="2016-01-20" version="1">MQEFVATLLEASGPLRVLAAQGVYLSQPFLGRSMSGGEWDALALLLEDERESRSFIQYLREE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GPD3</accession>
    <name>A0A0N8GPD3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MFS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_01675</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80578">
        <property type="protein sequence ID" value="KPL80578"/>
        <property type="gene ID" value="ADN00_01675"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1094"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010290">
        <property type="entry name" value="TM_effector"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05977">
        <property type="entry name" value="MFS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="141"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="171"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="261"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="291"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="370"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="1"/>
            <end position="403"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL80578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="419" mass="45154" checksum="AA302560BB8C9171" modified="2016-01-20" version="1">MLHLPPALRHRKFALLWASLLISYAGSNMQLWTLYWHLRDLSDQPVVVSGIGLARFIPMLAFALFGGLVADLFNRRHIMFVSQLTMMAIATALGALTHSGMIQIWHIFALTAVQAVAAAFDIPARQSIIPNLVSKEDLPNAFSMSSIAINVGAIIGPGLSGLVISRMGLDAVYWINAVSYIAVLVAVLVMGKVQQETAAAPGSRRKAFSLESIREGIQFILHQPMILSTMLLDFFATFFSTADTLLPFVARDILRVDEIRYGWLAAAPSLGAMSVGLVVSQLRGIQNQGRLLLSAVTIYGAATILFGISQQFLLAMVALFLIGAGDSLSAIIRNTIRQIHTPDRLRGRAISVNQIFFLGGPQLGDIEAGLLAQAFGTPIAIITGGIGCILAVIGIAQRWPQLRSYNGDEPRPATSPEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GPK4</accession>
    <name>A0A0N8GPK4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Aldehyde:ferredoxin oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_00840</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AOR/FOR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061103.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00840"/>
    <dbReference type="EnsemblBacteria" id="KPL81146">
        <property type="protein sequence ID" value="KPL81146"/>
        <property type="gene ID" value="ADN00_00840"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3566"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016625">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.569.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.599.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.9.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013984">
        <property type="entry name" value="Ald_Fedxn_OxRdtase_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013985">
        <property type="entry name" value="Ald_Fedxn_OxRdtase_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013983">
        <property type="entry name" value="Ald_Fedxn_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036503">
        <property type="entry name" value="Ald_Fedxn_OxRdtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001203">
        <property type="entry name" value="OxRdtase_Ald_Fedxn_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036021">
        <property type="entry name" value="Tungsten_al_ferr_oxy-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01314">
        <property type="entry name" value="AFOR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02730">
        <property type="entry name" value="AFOR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00790">
        <property type="entry name" value="AFOR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48310">
        <property type="entry name" value="SSF48310"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56228">
        <property type="entry name" value="SSF56228"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AFOR_N" evidence="8">
        <location>
            <begin position="22"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL81146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="713" mass="80189" checksum="558B00E4856DCE88" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WQ19</accession>
    <name>A0A0P6WQ19_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Urocanate hydratase</fullName>
            <shortName evidence="9">Urocanase</shortName>
            <ecNumber evidence="4 9">4.2.1.49</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 9">Imidazolonepropionate hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">hutU</name>
        <name evidence="13" type="ORF">ADN00_17850</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the conversion of urocanate to 4-imidazolone-5-propionate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>4-imidazolone-5-propanoate = H2O + trans-urocanate</text>
            <dbReference type="Rhea" id="RHEA:13101"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17771"/>
            <dbReference type="ChEBI" id="CHEBI:77893"/>
            <dbReference type="EC" id="4.2.1.49"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
        <text evidence="9">Binds 1 NAD(+) per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Amino-acid degradation; L-histidine degradation into L-glutamate; N-formimidoyl-L-glutamate from L-histidine: step 2/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the urocanase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.49" evidence="4 9"/>
    <dbReference type="EMBL" id="LGCL01000043">
        <property type="protein sequence ID" value="KPL70899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064400.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000043.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17850"/>
    <dbReference type="EnsemblBacteria" id="KPL70899">
        <property type="protein sequence ID" value="KPL70899"/>
        <property type="gene ID" value="ADN00_17850"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2153"/>
    <dbReference type="UniPathway" id="UPA00379">
        <property type="reaction ID" value="UER00550"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016153">
        <property type="term" value="F:urocanate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019556">
        <property type="term" value="P:histidine catabolic process to glutamate and formamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019557">
        <property type="term" value="P:histidine catabolic process to glutamate and formate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00577">
        <property type="entry name" value="HutU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023637">
        <property type="entry name" value="Urocanase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035401">
        <property type="entry name" value="Urocanase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038364">
        <property type="entry name" value="Urocanase_central_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023636">
        <property type="entry name" value="Urocanase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035400">
        <property type="entry name" value="Urocanase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035085">
        <property type="entry name" value="Urocanase_Rossmann-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036190">
        <property type="entry name" value="Urocanase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12216">
        <property type="entry name" value="PTHR12216"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01175">
        <property type="entry name" value="Urocanase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17392">
        <property type="entry name" value="Urocanase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17391">
        <property type="entry name" value="Urocanase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001423">
        <property type="entry name" value="Urocanate_hydrat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111326">
        <property type="entry name" value="SSF111326"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01228">
        <property type="entry name" value="hutU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01233">
        <property type="entry name" value="UROCANASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0369">Histidine metabolism</keyword>
    <keyword evidence="7 9 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 9" id="KW-0520">NAD</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Urocanase_N" evidence="11">
        <location>
            <begin position="7"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="Urocanase" evidence="10">
        <location>
            <begin position="136"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="Urocanase_C" evidence="12">
        <location>
            <begin position="346"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="405"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="48"/>
            <end position="49"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="172"/>
            <end position="174"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="238"/>
            <end position="239"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="268"/>
            <end position="269"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="317"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="487"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00031640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF17391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF17392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KPL70899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="551" mass="60002" checksum="30596C6722ABC087" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WVR6</accession>
    <name>A0A0P6WVR6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13765</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the asp23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063601.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000032.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13765"/>
    <dbReference type="EnsemblBacteria" id="KPL74358">
        <property type="protein sequence ID" value="KPL74358"/>
        <property type="gene ID" value="ADN00_13765"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005531">
        <property type="entry name" value="Asp23"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34297">
        <property type="entry name" value="PTHR34297"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03780">
        <property type="entry name" value="Asp23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="118" mass="12587" checksum="6A9D54CB50FB108D" modified="2016-01-20" version="1">MTDANNPLGNIYISHRAIATIACQSALESYGVVGLAAKNFAEGITQAIVKDPLAGVEVNFTGSEIKIDLYIIIEYGTRIKSVASSVGDSVRYQVEKATGLPVLQVNVHVRGLRISNPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WVX6</accession>
    <name>A0A0P6WVX6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_18865</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064592.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70105">
        <property type="protein sequence ID" value="KPL70105"/>
        <property type="gene ID" value="ADN00_18865"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021145">
        <property type="entry name" value="Portal_protein"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05133">
        <property type="entry name" value="Phage_prot_Gp6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="432" mass="49419" checksum="5CEFBEC8A99CDA19" modified="2016-01-20" version="1">MNADLKLAFESIIEKQKDHTEKFNYYDGQQPLVYLTYRLREIFQGLDIEFMDNWCAVVIDAVKERINLTGLNVPKAHQNAMNKIWTLNELNLEADEVHESALVTGEAFMIAWPDEKKMPKAYYNDPRLCHSFYHSDNPRELRMAAKMWVDDDGYYRLTLYYPDRLEYYASTQKADQVSSHKSFKAMETPSAKNPYGKIPVFHFRLERRGRKSDLTSVIPLQRGVNKLLNDMMVAAEFGAFKQRYVISQVDVSRLKNAPNEVWSIPGSDGTGQGTEVGEFGATPLQNYIEAIDKLAGDMGRITRTPKHYFYHQGGDPSGEALIAQEAPLNKKAQDRIEKFSSVWRRLGSFLLELKGINVNPMEITPVWDPVETVQPRTQAEIRLLDRQSGIPLITVCRRSGWPQVEIDQMLQEAEADVEGLGERILSAFDKGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WYC0</accession>
    <name>A0A0P6WYC0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_17380</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064317.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17380"/>
    <dbReference type="EnsemblBacteria" id="KPL71455">
        <property type="protein sequence ID" value="KPL71455"/>
        <property type="gene ID" value="ADN00_17380"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006553">
        <property type="entry name" value="Leu-rich_rpt_Cys-con_subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13516">
        <property type="entry name" value="LRR_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00367">
        <property type="entry name" value="LRR_CC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL71455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="175" mass="19726" checksum="3115C437C4CB8C34" modified="2016-01-20" version="1">MTSTACQFSSRFPIQIFTRPLGLSGPETWREFDLGPGYFSIPEGHEVMVRARNIDDAQLLELITELEECPAITHLNLSENRKVTDASLPALARLKRLTWLNLSSCMITNRGLPSLTGLSRVTHLNLSYCNKLSDTGLKDLRAMRGLRFLDLQGCPKVTRSGLARIERHNLEIYKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WYD7</accession>
    <name>A0A0P6WYD7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_17550</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064349.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17550"/>
    <dbReference type="EnsemblBacteria" id="KPL71483">
        <property type="protein sequence ID" value="KPL71483"/>
        <property type="gene ID" value="ADN00_17550"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027476">
        <property type="entry name" value="DppA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007035">
        <property type="entry name" value="Peptidase_M55"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036177">
        <property type="entry name" value="Peptidase_M55_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04951">
        <property type="entry name" value="Peptidase_M55"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015853">
        <property type="entry name" value="Pep_DppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63992">
        <property type="entry name" value="SSF63992"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="116"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="8"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="104"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR015853-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR015853-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL71483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="274" mass="29459" checksum="53508BD4493F3BCA" modified="2016-01-20" version="1">MKLLIAADMEGISGVVNWNQVTSTHPDYARFRRLMTQDVNAAIDGAFRGGASEIIVADGHAGGYNILIEELDPRVSLNSGNPAPWAMIQGIDASFQGVMFIGYHAHMGTQSANLDHTWSSSQVANVWLNERLVGEAQINGGICGHYDVPVLMASGDQALAADLTEWIPGIEMAVVKQATSRYSGQCLPPAVSQKRISAAAEQAVKKALQGGAPRPLQFEAPVTVTVEFMHSAMADGAALLPYAQRVDARKVSFKAEDMLMAFRAFRAMVTLADR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZ57</accession>
    <name>A0A0P6WZ57_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NGN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_15970</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL71995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15970"/>
    <dbReference type="EnsemblBacteria" id="KPL71995">
        <property type="protein sequence ID" value="KPL71995"/>
        <property type="gene ID" value="ADN00_15970"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006645">
        <property type="entry name" value="NGN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036735">
        <property type="entry name" value="NGN_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02357">
        <property type="entry name" value="NusG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00738">
        <property type="entry name" value="NGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82679">
        <property type="entry name" value="SSF82679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="NGN" evidence="2">
        <location>
            <begin position="1"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL71995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="173" mass="19520" checksum="51225698C6DD92EB" modified="2016-01-20" version="1">MKHWYAMRSHPHKEDALYQQLLRKEHEAFYPRIRVQPVNPRARKIRPYFPGYLFICADIEETGLSELNFMPYGSGLVSFGGEPAVIPDNLIAAIRQRVSEIEAAGGELFDGLSSGDPVRVESGPFKGYEAIFDTRIPGTQRVKILLKMLSSYQGLPVEMDAGSIKRLPPKKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZF4</accession>
    <name>A0A0P6WZF4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Baseplate_J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_15145</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15145"/>
    <dbReference type="EnsemblBacteria" id="KPL72168">
        <property type="protein sequence ID" value="KPL72168"/>
        <property type="gene ID" value="ADN00_15145"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006949">
        <property type="entry name" value="Baseplate_J-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04865">
        <property type="entry name" value="Baseplate_J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="Baseplate_J" evidence="2">
        <location>
            <begin position="202"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL72168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="491" mass="53537" checksum="1E4C7413197AFA11" modified="2016-01-20" version="1">MIQLERHDDYLSAKDKISWSKAQRVLLVWPERGRPKIFALDLKLLDRYAASSGARLALVTQNIAITEEAYHQGIPVFETIEQARKNSWRVPREWRKSRVAGAEKRTDFKQLVAQHADRKASARLPKWVEMAAFVLGLFAVFGLFLFFAPGATIHIDSAEELQTLEMPMWASPEIKAANLAGGIPANPRTIMVEGEDSIETSGVSLVPTQFAKGKVLFSNLTEDDLLIPRGTVVLSGGDPALRYQTLQAVALGGKNSVEVEVEALQGGSASNVAAGEIRGIEGVVGLSASVENLEAIQGGSEAEGKSAAAADFDRLRARLIEELRQQALRQFQTQAGIGELTIPESLSVGDIIDEAFSVEEGQPADQLTLALKMEFSLWVISEADMKIAANSAMDATLPAGYQALEDSLLVSMVNTPRMQNQRAVWAVRAERSLKPRIDPGDVYHAALGKPAQEAVQRLADLPGVEAVNVQTKPGWWPVISYLPQRISIEVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X113</accession>
    <name>A0A0P6X113_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">GTPase Obg</fullName>
            <ecNumber evidence="6">3.6.5.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">GTP-binding protein Obg</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">obg</name>
        <name evidence="10" type="ORF">ADN00_11615</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">An essential GTPase which binds GTP, GDP and possibly (p)ppGpp with moderate affinity, with high nucleotide exchange rates and a fairly low GTP hydrolysis rate. Plays a role in control of the cell cycle, stress response, ribosome biogenesis and in those bacteria that undergo differentiation, in morphogenesis control.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="6">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. OBG GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.-" evidence="6"/>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063183.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11615"/>
    <dbReference type="EnsemblBacteria" id="KPL76004">
        <property type="protein sequence ID" value="KPL76004"/>
        <property type="gene ID" value="ADN00_11615"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3798"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01898">
        <property type="entry name" value="Obg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.210.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01454">
        <property type="entry name" value="GTPase_Obg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031167">
        <property type="entry name" value="G_OBG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014100">
        <property type="entry name" value="GTP-bd_Obg/CgtA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036346">
        <property type="entry name" value="GTP-bd_prot_GTP1/OBG_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006074">
        <property type="entry name" value="GTP1-OBG_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006169">
        <property type="entry name" value="GTP1_OBG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036726">
        <property type="entry name" value="GTP1_OBG_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045086">
        <property type="entry name" value="OBG_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015349">
        <property type="entry name" value="OCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11702">
        <property type="entry name" value="PTHR11702"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09269">
        <property type="entry name" value="DUF1967"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01018">
        <property type="entry name" value="GTP1_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002401">
        <property type="entry name" value="GTP_bd_Obg/CgtA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102741">
        <property type="entry name" value="SSF102741"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82051">
        <property type="entry name" value="SSF82051"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02729">
        <property type="entry name" value="Obg_CgtA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03595">
        <property type="entry name" value="Obg_CgtA_exten"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51710">
        <property type="entry name" value="G_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00905">
        <property type="entry name" value="GTP1_OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51883">
        <property type="entry name" value="OBG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51881">
        <property type="entry name" value="OCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Obg" evidence="9">
        <location>
            <begin position="1"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="OBG-type G" evidence="7">
        <location>
            <begin position="159"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="OCT" evidence="8">
        <location>
            <begin position="342"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="165"/>
            <end position="172"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="190"/>
            <end position="194"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="212"/>
            <end position="215"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="279"/>
            <end position="282"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="308"/>
            <end position="310"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL76004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="419" mass="45822" checksum="E2D0E45FA6F29DD7" modified="2016-01-20" version="1">MFIDEACIFVRSGKGGDGMVHFHREKYVPRGGPDGGDGGKGGDVVLEVIPTLNTLSNFRHQTRYEAKSGAAGGPNNMSGRSAEDLIIPVPPGTLVYNDATGELMGDLVSAGQRLIVCKGGRGGRGNQHYASSRNQVPRMATKGEPSEELNLRLELKLIADAGLVGVPNAGKSSLLAAVTNARPKIAPYPFTTIEPNLGVVELDDTHTMILADIPGLIEGAHMGVGLGDAFLRHIQRTRVLVHILDGLSEDPLADFSQINSEMALFDPGLARKPQIIAFNKMDLPEVQEKWAAIKKVLEKKGYEVFSISAAARQDLRPLMWRVYQLIEETPEPEIKEELPVYRVEEAPSAFEIFQDEEGYHVTGKAIERAAAMTYWEHDASVRRFHKILNVLGIEDALIKAGVEEGDTVFIGDYELEWSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X188</accession>
    <name>A0A0P6X188_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_12290</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063310.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76113">
        <property type="protein sequence ID" value="KPL76113"/>
        <property type="gene ID" value="ADN00_12290"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="204" mass="23471" checksum="13C01F8A9621E48D" modified="2016-01-20" version="1">MKKSQSQFYELIFDGYAIEDNPLSIYYERRDDQGFDNRLLNRGNSLEDLWPQDFTIYLRGYQPVDYLMCGPGYEVLSKSAADIFHSIAKDSIELLPVNTVINDQPVEPNSFFVLNVLKSFEALNWEETVWSSPKVPYDDPSAHGRIIKPAFNIQLIQEEAIFLLSVQKKIKSGIYISRYLKESLEERNSTIGMAFTPIKVVIQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X190</accession>
    <name>A0A0P6X190_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_14935</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000036">
        <property type="protein sequence ID" value="KPL73083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063834.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000036.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL73083">
        <property type="protein sequence ID" value="KPL73083"/>
        <property type="gene ID" value="ADN00_14935"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL73083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="75" mass="8206" checksum="15C15B31392C147C" modified="2016-01-20" version="1">MSNEKRAKTPWYLWPFVALWDLLAFILSLTGRLVGSLLGMALMIVGLVLTVTIIASPVGIPILIVGLLIVLRSLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X1N3</accession>
    <name>A0A0P6X1N3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Xylulose kinase</fullName>
            <shortName evidence="3 5">Xylulokinase</shortName>
            <ecNumber evidence="3 5">2.7.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">xylB</name>
        <name evidence="8" type="ORF">ADN00_13505</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 5">
            <text>ATP + D-xylulose = ADP + D-xylulose 5-phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10964"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17140"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.17"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the FGGY kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.17" evidence="3 5"/>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063549.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000031.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13505"/>
    <dbReference type="EnsemblBacteria" id="KPL74848">
        <property type="protein sequence ID" value="KPL74848"/>
        <property type="gene ID" value="ADN00_13505"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1194"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004856">
        <property type="term" value="F:xylulokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042732">
        <property type="term" value="P:D-xylose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005998">
        <property type="term" value="P:xylulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02220">
        <property type="entry name" value="XylB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000577">
        <property type="entry name" value="Carb_kinase_FGGY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="Carb_kinase_FGGY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018483">
        <property type="entry name" value="Carb_kinase_FGGY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018484">
        <property type="entry name" value="Carb_kinase_FGGY_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006000">
        <property type="entry name" value="Xylulokinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02782">
        <property type="entry name" value="FGGY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00370">
        <property type="entry name" value="FGGY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000538">
        <property type="entry name" value="GlpK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01312">
        <property type="entry name" value="XylB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00445">
        <property type="entry name" value="FGGY_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 3 5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3 4 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0808">Transferase</keyword>
    <keyword evidence="1 3 5" id="KW-0859">Xylose metabolism</keyword>
    <feature type="domain" description="FGGY_N" evidence="6">
        <location>
            <begin position="3"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="FGGY_C" evidence="7">
        <location>
            <begin position="259"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="81"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="240"/>
        </location>
    </feature>
    <feature type="site" description="Important for activity" evidence="3">
        <location>
            <position position="8"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL74848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="497" mass="54117" checksum="0A2D4ED09086432B" modified="2016-01-20" version="1">MPYFLGIDVSTTATKALLIDSSGKVIAVHSTTYGFETPHPLWSEQDPELWWNGTQQSIRSVLEESAVDPSEIFGVGLTGQMHGLVLLDAAQNVLRPAILWNDQRTQAQCDEIHQRIGRERFIQISGNVALTGFTAPKILWVREKEPEVYARVTNVLLPKDFIRHRLTGEFAMDMADGSGTVLMDLKQRNWSEEILDGLEIPRSWMPRLYEGQEITGRITPEAAQATGLKPGTPVMAGGGDQAAQAVGVGAVEPGIIGLTVGTSGVVFATTPSALIEPQGRLHAFCHAVPGRWHFMGVMLSAAGSLQWYHDTLAPEMSIADLVRESEDIPAGSDGLQFLPYLSGERTPYPDPLARGAFIGLTVRHKRAHMTRAVLEGVAYGLKDSFQLIQNSGLGQINQVRASGGGTKSRLWRQILASVLEAELVTVNTTEGAAYGAALLAGVGAGYWKDVDEACKAAIKLTGKEEPQSAEMEQYRKGYEVYQKLYPALKDTFKLMGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X2L7</accession>
    <name>A0A0P6X2L7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GPW_gp25 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062837.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09890"/>
    <dbReference type="EnsemblBacteria" id="KPL76900">
        <property type="protein sequence ID" value="KPL76900"/>
        <property type="gene ID" value="ADN00_09890"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007048">
        <property type="entry name" value="IraD/Gp25-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04965">
        <property type="entry name" value="GPW_gp25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GPW_gp25" evidence="1">
        <location>
            <begin position="30"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="137" mass="15449" checksum="C8D43C419FFBB1FC" modified="2016-01-20" version="1">MPLNAKTFLGNGLNFPLKTDARGQLVLVTGAEDIEQSIRIILSTRPGERVMRPTFGCRAHELLFEPRSAATASLLQEYVYQALRMWEPRIDILQVNVIHDSGQEGALLAEIHYEIKATHDARSIVFPFYIADEPELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X353</accession>
    <name>A0A0P6X353_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Acetyltransf_6 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_08945</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062654.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77256">
        <property type="protein sequence ID" value="KPL77256"/>
        <property type="gene ID" value="ADN00_08945"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038740">
        <property type="entry name" value="BioF2-like_GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13480">
        <property type="entry name" value="Acetyltransf_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acetyltransf_6" evidence="1">
        <location>
            <begin position="170"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="410" mass="47411" checksum="91D23082CFACA647" modified="2016-01-20" version="1">MKNFYQSFKVKVNAWMDRVILFCSKKMVQFNLIRQPRLRRIVISFFRWIGSLALFVKQFPRLEAYTCQHALGKFIFLGVEKIECVLFLRQIDHELNDVDLEPVGRVYLWALPKQVDRWLTEGVDAVVCDLSRTYPLAFNTNYQIKTPIIIEQVIYLPDSAEAFLSGSKFRELRRRIYQAQRSNITYRFSQEKSDFDNFHYHMYLPYIQKRHGDFADINDYEAQWKEFQKGGLVMVCKDDQTIAGSLVQSAEDFAIGLEGGVLDVDPDLLPKNVYSLMFWACIEWALAKGAKRFDLGTTYASRNNGIFRFKKSFTARVESQPRFIFPNRMILMNHPSAGLVSALNETGWIYEKNGKHFGVILDESQDLAHDGYAKDLDRAVGDGLDGIVVLKPKQKKFIEAPDKSSLQGIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5T9</accession>
    <name>A0A0P6X5T9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_09025</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062669.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77271">
        <property type="protein sequence ID" value="KPL77271"/>
        <property type="gene ID" value="ADN00_09025"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4039"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002838">
        <property type="entry name" value="AIM24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036983">
        <property type="entry name" value="AIM24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016031">
        <property type="entry name" value="Trp_RNA-bd_attenuator-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01987">
        <property type="entry name" value="AIM24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51219">
        <property type="entry name" value="SSF51219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00266">
        <property type="entry name" value="TIGR00266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL77271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="227" mass="23673" checksum="3042F43B4EB94477" modified="2016-01-20" version="1">MNIEILYRPSYSMGVIRLNGGEGVQVEGGSMVSMSPGVQVETRASGGLLKSLGRALLGGESFFVNTYTASAQGGEVMVAPALPGDLVTLDLNGESLLVQSGSYVASESTIQVNTKWSGAKTFFASEGFIMLNVSGRGKVVLSSYGAIHEMVLAAGQSYTVDTGHLVAFTEGMGFHVRSIGGIKSTLFSGEGLVVDLTGPGRVLMQTRSTDAFIAWLTPHLPTPSSNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7I3</accession>
    <name>A0A0P6X7I3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">CRISPR-associated endonuclease Cas1</fullName>
            <ecNumber evidence="8">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">cas1</name>
        <name evidence="9" type="ORF">ADN00_13030</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer, forms a heterotetramer with a Cas2 homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the CRISPR-associated endonuclease Cas1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="8"/>
    <dbReference type="EMBL" id="LGCL01000028">
        <property type="protein sequence ID" value="KPL75308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063459.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000028.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13030"/>
    <dbReference type="EnsemblBacteria" id="KPL75308">
        <property type="protein sequence ID" value="KPL75308"/>
        <property type="gene ID" value="ADN00_13030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2721"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043571">
        <property type="term" value="P:maintenance of CRISPR repeat elements"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.100.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01470">
        <property type="entry name" value="Cas1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002729">
        <property type="entry name" value="CRISPR-assoc_Cas1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042206">
        <property type="entry name" value="CRISPR-assoc_Cas1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042211">
        <property type="entry name" value="CRISPR-assoc_Cas1_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01867">
        <property type="entry name" value="Cas_Cas1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00287">
        <property type="entry name" value="cas1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="7 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 8" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="2 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 8" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="8">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="222"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="237"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL75308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="332" mass="37802" checksum="CD76A210FE71EE17" modified="2016-01-20" version="1">MASLYVIETGARVEVEYQRVIVTAEDETIFRAPIQHVSQVVLIGSAGVTTPALHKLLHAGIPLLFLDYRGRFLGRLQPASSYQLPLRLAQYQKNDDPEFCLRTARAIVCGKIKNQRTYLRRLAHRGAEISPSDLLEMKTGAAKAAQAGDLPGLLGVEGYTARIFFNGYRRAFNPEWNFTRRARRPPKDAVNAMLSLGYTLLNQAVIAAIEITGLDPYLGYFHVEKYGRPALALDLVEEFRTPIVDSLVYDLASHHRLTPEDFQSDTFGRATRLTRSGMRRFVKEFSRKMESEIKTRELDRPLSYQKHLEVQARKMARCIQGQETQYQPFQIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X8H3</accession>
    <name>A0A0P6X8H3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_17505</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064340.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17505"/>
    <dbReference type="EnsemblBacteria" id="KPL71476">
        <property type="protein sequence ID" value="KPL71476"/>
        <property type="gene ID" value="ADN00_17505"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="428"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL71476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="462" mass="53131" checksum="F525D41069C297F8" modified="2016-01-20" version="1">MSGHKKTVVHISEEEYERLHQAEMQQRFQRSQQTSNEKMLQAASQHLQAELSEVSRRQNDYLRHIARLDQTIQSIEYEASRTLVDQQTLLLEEINSAAQQVAESNEIQIQQVHQQLFQEMDNLRAGMDDQLASLQSEWAQQLQSRRQVFEYATYWLDSAETLASFIAVNYDHNHFSPGALQNIDQLIQQSVQNLQNSAPEAAISLAQQAYRESSQLRLSLEQAQTEWHALQSQALQGISRLQTLLDGCQTLPALDLNGAELPVLLNIEFWSQGEYRRLFNDLRDLEARVQMDWRQQPMESLNELCKHTLPELQQRLDRMIYHARLAALNSQLRINIADIVIQALETQGFSLQTSAYQKDDFHQLFQAQLSNYEGSQVIVEVVPTGNGQRENELHIHSLDAAQHTPHELRRRALEINRSLNEMGLQTGELETLPPTTSPPPSIHSIPIPARRSLRRPSLRPHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X8Z3</accession>
    <name>A0A0P6X8Z3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_06615</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000017">
        <property type="protein sequence ID" value="KPL78588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062190.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000017.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06615"/>
    <dbReference type="EnsemblBacteria" id="KPL78588">
        <property type="protein sequence ID" value="KPL78588"/>
        <property type="gene ID" value="ADN00_06615"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2831"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="393" mass="45266" checksum="92382528D66A0AE0" modified="2016-01-20" version="1">MQTQSAHPTSHYNFILAGGGAAGLSLAVQLASSPLKDRSILIIDRDRKQANDRTWCFWARTPTLFDSIAYRVWERVEFVAPGFQRVYDLPPYHYQMIRGIDFYNYARQVLSQFSNIHFLQAGVESVEDGPDAARVTAGGEVYTADWVFNSLYLAGQVRPNPARHHSLLQHFRGWEIETEQDAFDPKLPRMFDFRTPQHGEMRFVYILPFNPRRALVEFTLFSANLLTDAEYDQALRDYLQSVLGLQSYRVLEVENGVIPMTDQPFARRAGQRVLNIGTRGGRVKPSSGYAFLRIQRDSAAILQSLLAHGHPFHLPESPARYRLYDSILLQILYRHGELSQRIFTALFRRNSIQRIFRFLDEEAPLPENALLMATLPTWPFVRALLKLKLLHRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X916</accession>
    <name>A0A0P6X916_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glyco_trans_2-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_11950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063246.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11950"/>
    <dbReference type="EnsemblBacteria" id="KPL76057">
        <property type="protein sequence ID" value="KPL76057"/>
        <property type="gene ID" value="ADN00_11950"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3866"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="4"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="256" mass="29834" checksum="9A9251543B80EEBE" modified="2016-01-20" version="1">MLVSIITPSYNQVAFLEKTIRSVLEQDYPEIEYIVVDGSSTDGSVDVIKKYENRLAWWVSEKDRGQTDAINKGFARARGEIIAWLNSDDTYEPGAVREAVEYLKSHPEVGLVYGHVKFIDARDQVIGDFPSAQTSYAKLRQGYVHMGQQAAFFRNDLWKKVGPLDPSFYFAMDYDLWVRLAREAPIVYHPRHWANFRLHGDAKTVAADDRCWPEMLRVHRREGGSWFSVIYAKYWVRKLAAPLINWRRRKLFERKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9J6</accession>
    <name>A0A0P6X9J6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09910</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062841.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76904">
        <property type="protein sequence ID" value="KPL76904"/>
        <property type="gene ID" value="ADN00_09910"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2442"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="479"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="530"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="129"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="249"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="299"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="573"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="625"/>
            <end position="639"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="671" mass="69860" checksum="46FAD87E388F2386" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9L1</accession>
    <name>A0A0P6X9L1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ABC transmembrane type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_05865</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062036.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05865"/>
    <dbReference type="EnsemblBacteria" id="KPL78761">
        <property type="protein sequence ID" value="KPL78761"/>
        <property type="gene ID" value="ADN00_05865"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="222"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="56"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL78761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="263" mass="29212" checksum="9F1AB1C92383ED07" modified="2016-01-20" version="1">MEQKKNKFKENLPPILLILGIVALWEAASLWFKIPDYLLPRPSQIISISFLKRASLYAHLMVTLEEVLLGFLVGFVVGYILALLMFFSETLRKALNPIVVISQTIPVIALGPILVIWLGYNIWPKIIVVALIVFFPVTVNTFDGLVSCDPDLITLLKSMGASKWQIFTKVQLMNALPFITSATKVAITYSVIGAVVAEWIGSDKGLGAYILQSNAQIRTPQMFAAILITSLMGILMFFVAQLAENLLIPWQKGGKTKKKKYIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9N6</accession>
    <name>A0A0P6X9N6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_05980</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78780.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062058.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05980"/>
    <dbReference type="EnsemblBacteria" id="KPL78780">
        <property type="protein sequence ID" value="KPL78780"/>
        <property type="gene ID" value="ADN00_05980"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1674"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132938" evidence="2">
        <location>
            <begin position="22"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="227"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="261"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78780.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="285" mass="30979" checksum="4F346891B40FE3E5" modified="2016-01-20" version="1">MKNSKALFILPLMIAALALVAAALGVFWQGSGEPIEFTSVFGETYTLQGRGVYQHDTINYAAQAKSQDIITLFLGIPLLITGVILNKKGTLRGRLILTGALGYFLYTYTSLVFLAAYNSFFLIYVALFSMSLFTFILAMMGLKPDQIAERVTRRFPRRWVITFLVILSLFLLMAWLGLIVPSLTNGGAPSGLETYTTLVIQALDLGIIVPVSLLSAYLLWKKQAWGYALSFVVMLKGSLMGAAIIAMIVGQALAGVPFDPVMAAIFALICLCGIGLAAVMLKNIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9R8</accession>
    <name>A0A0P6X9R8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10245</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062906.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76959">
        <property type="protein sequence ID" value="KPL76959"/>
        <property type="gene ID" value="ADN00_10245"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2514"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="183" mass="19775" checksum="67C4103EF1B6A564" modified="2016-01-20" version="1">MTTKVKTLYLSRFNMPTMCAACHSPNGYGKGLKVSSSKSNWSGKETATLTVELPLCEECAKVNVVSGTGKFLKALGFIGVIAACLLIAGLNATDAIKNPLVSIVSGAVLITAIIIGTNKLVNEVDMKGFTPEQRERRKKVQKCAKIQSFKLPGVFDNQSFVVFEFQDPLFAMEFSTLNMGTIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAS4</accession>
    <name>A0A0P6XAS4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_09670</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062797.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76862">
        <property type="protein sequence ID" value="KPL76862"/>
        <property type="gene ID" value="ADN00_09670"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="74" mass="8155" checksum="6EE9A74ECCE00C35" modified="2016-01-20" version="1">MAECECLGGCPFFNDKMSDADGLGALFKKRYCLGDNSKCARYMVFKALGKPSVPANLYPNMVDQANEIIQKAQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAW3</accession>
    <name>A0A0P6XAW3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Baseplate_J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09885</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76899.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062836.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09885"/>
    <dbReference type="EnsemblBacteria" id="KPL76899">
        <property type="protein sequence ID" value="KPL76899"/>
        <property type="gene ID" value="ADN00_09885"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2437"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006949">
        <property type="entry name" value="Baseplate_J-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011749">
        <property type="entry name" value="CHP02243"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04865">
        <property type="entry name" value="Baseplate_J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02243">
        <property type="entry name" value="TIGR02243"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Baseplate_J" evidence="1">
        <location>
            <begin position="415"/>
            <end position="589"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76899.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="697" mass="77716" checksum="015EF8889F7343BC" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBF6</accession>
    <name>A0A0P6XBF6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">MFS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_16200</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064084.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72028">
        <property type="protein sequence ID" value="KPL72028"/>
        <property type="gene ID" value="ADN00_16200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039309">
        <property type="entry name" value="BT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03092">
        <property type="entry name" value="BT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="102"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="209"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="249"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="277"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="301"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="335"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="364"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="8">
        <location>
            <begin position="212"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL72028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="398" mass="42679" checksum="C163B86FDDE35130" modified="2016-01-20" version="1">MSQPITRKIMFGLLYFTQGTILSYFTALNALYFLSKGLSMTSVGIFATIALIPFVIKIFLGMWSDRVNLFGMGHRKPYIIIGLTVQFVALVIVPFIDPAKSYWGFVGLAFILQLGMALYDTCTDGLALDTTTEEEHGVIQGIMVGGRALGVVITASAVGIMAEAVSWLAVFWLLAGLTLLPLPFVLGIREGERTVERKFDWSAFSAFKQASIIGLAGIGFVFFMIIAGVNQLVNPFLEQDFGISLSQAGFYTTVWGIGVVLGGVTGGWLISKIGSRNGVIASVVVSAISTLLLAATPNPQIAWFVVALFGIAYGTYQTVYFALAMNYTDSRIAASMFSILMAVSNVAQGAGMGLTGFMADTVGFRWTFIAFTAINILVFPLLPLVFGKASQQVKAAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XCC1</accession>
    <name>A0A0P6XCC1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Small ribosomal subunit biogenesis GTPase RsgA</fullName>
            <ecNumber evidence="3">3.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rsgA</name>
        <name evidence="6" type="ORF">ADN00_01465</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="3"/>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061185.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01465"/>
    <dbReference type="EnsemblBacteria" id="KPL80539">
        <property type="protein sequence ID" value="KPL80539"/>
        <property type="gene ID" value="ADN00_01465"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1047"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01854">
        <property type="entry name" value="YjeQ_EngC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01820">
        <property type="entry name" value="GTPase_RsgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030378">
        <property type="entry name" value="G_CP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004881">
        <property type="entry name" value="Ribosome_biogen_GTPase_RsgA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010914">
        <property type="entry name" value="RsgA_GTPase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32120">
        <property type="entry name" value="PTHR32120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03193">
        <property type="entry name" value="RsgA_GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00157">
        <property type="entry name" value="TIGR00157"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50936">
        <property type="entry name" value="ENGC_GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51721">
        <property type="entry name" value="G_CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CP-type G" evidence="5">
        <location>
            <begin position="99"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="ENGC_GTPASE" evidence="4">
        <location>
            <begin position="105"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="145"/>
            <end position="148"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="202"/>
            <end position="210"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="284"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="290"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="292"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="298"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL80539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="328" mass="35907" checksum="78350FE65E50F6CE" modified="2016-01-20" version="1">MKNKNNNIHDGVVIKKNNGQYWVWSNGRELRCGLNLHSNPANGKGKNKPTRAASPEIVVGEQVGVTMNADGCAQICEVYERSNRLARRAAQSMPGSRASEQVIAANIDQIVAVMSLSQPAPRWNLLDRYLASAESLEIEALICLTKADAARGDSGELDEAARAEIETYRQIGYRVLLTSAVSGEGLPELKQALGGRVSVLLGKSGAGKSSLLNALLPGLNLRVGEINAVTGKGRHTTTGAEMHACDYGGWLVDTPGTREFGLWDVDSDDLAWFFPEMRPWLGQCRFGLDCQHDEEPGCALRQAVMSGHISPRRYFSMMKLKEEGYFQW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDC3</accession>
    <name>A0A0P6XDC3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ADN00_07190</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062303.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07190"/>
    <dbReference type="EnsemblBacteria" id="KPL78248">
        <property type="protein sequence ID" value="KPL78248"/>
        <property type="gene ID" value="ADN00_07190"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3258"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035596">
        <property type="term" value="F:methylthiotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005839">
        <property type="entry name" value="Methylthiotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020612">
        <property type="entry name" value="Methylthiotransferase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013848">
        <property type="entry name" value="Methylthiotransferase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038135">
        <property type="entry name" value="Methylthiotransferase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006467">
        <property type="entry name" value="MiaB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00919">
        <property type="entry name" value="UPF0004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01061">
        <property type="entry name" value="methylthiotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01579">
        <property type="entry name" value="MiaB-like-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00089">
        <property type="entry name" value="TIGR00089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51449">
        <property type="entry name" value="MTTASE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01278">
        <property type="entry name" value="MTTASE_RADICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MTTase N-terminal" evidence="8">
        <location>
            <begin position="1"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="9">
        <location>
            <begin position="125"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL78248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="417" mass="46120" checksum="0ABFD31B526AF9BC" modified="2016-01-20" version="1">MKVFVDTVGCRLNQSEIEKIAAQFRAEGYEITGEVSEADLVVVNTCAVTARASADSRKAIRHATHAGNAQLVVTGCWATLSPDEAAAMPGVSRVVSNLQKDQLVSLVVGREHVFEPESRQPLPGGRRRTRAFIKVQDGCNNFCTYCVTRIARGAARSVTSEEVLAEVRAAAAGGAKEAVLTGVHLGSWGQDFAEQQHLKDLVELILQETSIARLRLSSLEPWDLDEEFFRLWQNPRLCAHLHLPLQSGCARTLKRMARKITPDNFRLLVNNARRYAPEMAITTDMIVGFPGETDEDFEESLAFAREMSFAGGHVFAFSPRAGTPAANYPDQIESQVKKERSQRLRKLFAEMEGAYAQQFIGRSLDVLWEDQSEDGSLKGLSGNYLKVCSASSQNLWNEVSRVKIIRKNGGDLYGEIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDT7</accession>
    <name>A0A0P6XDT7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_00665</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MgtC/SapB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061021.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00665"/>
    <dbReference type="EnsemblBacteria" id="KPL81075">
        <property type="protein sequence ID" value="KPL81075"/>
        <property type="gene ID" value="ADN00_00665"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3528"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003416">
        <property type="entry name" value="MgtC/SapB/SrpB/YhiD_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33778">
        <property type="entry name" value="PTHR33778"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02308">
        <property type="entry name" value="MgtC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01837">
        <property type="entry name" value="MGTCSAPBPROT"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="95"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL81075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="155" mass="16622" checksum="420B5807D592A503" modified="2016-01-20" version="1">MWNDIYLSVFVRAWLAGLFGFLIGWERVMVGSPVRARMVALAALNAAAITAISMEMFQADTGRILAGLVTGIGFLGAGVIMRVPTGEVSGLTTAASIWAMSAVGITVGSGNILLGLMLTVLVYVTISWNDWPVLNRLLQRQAQKQTQDAESRPPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XET6</accession>
    <name>A0A0P6XET6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05455</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78696.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061963.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05455"/>
    <dbReference type="EnsemblBacteria" id="KPL78696">
        <property type="protein sequence ID" value="KPL78696"/>
        <property type="gene ID" value="ADN00_05455"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="255"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="288"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="320"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="349"/>
            <end position="369"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78696.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="512" mass="56998" checksum="8BE530ABF750FAAA" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XF11</accession>
    <name>A0A0P6XF11_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA polymerase sigma factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_14460</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000034">
        <property type="protein sequence ID" value="KPL73761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063736.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000034.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL73761">
        <property type="protein sequence ID" value="KPL73761"/>
        <property type="gene ID" value="ADN00_14460"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000838">
        <property type="entry name" value="RNA_pol_sigma70_ECF_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50096">
        <property type="entry name" value="IQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01063">
        <property type="entry name" value="SIGMA70_ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="4">
        <location>
            <begin position="33"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="5">
        <location>
            <begin position="127"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="102"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL73761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="194" mass="21625" checksum="24066B63811FD183" modified="2016-01-20" version="1">MEWILERSTSEPIKDTQLLRRVAAGEEAALRALFEIYGQRMYAYALRWMGDPAAAEDVVQESLVAIWQSAGRYRGDGCPAAWLMGIVHFKALNALRRKETLSLDATESEPPAPGSLPEEKAAARADRESVRQALNQLSAEHRAVLELVFYGGMSLQEIAEVMNCPLGTVKSRLAYARAALRGYLDRQGLREEMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XF26</accession>
    <name>A0A0P6XF26_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_07155</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07155"/>
    <dbReference type="EnsemblBacteria" id="KPL78243">
        <property type="protein sequence ID" value="KPL78243"/>
        <property type="gene ID" value="ADN00_07155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_beta_propeller_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01011">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13360">
        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="354" mass="37912" checksum="3CF8A7163D4B3388" modified="2016-01-20" version="1">MKPKKLLIVISILMIGALLSGCGGGRVIGATSWPGVSIDEDTIFVAYNTEVYALKEADGSLIWRYPEEPNARRAFFAAPAYAEGLLLAGDYANSLTALSPDTAAIKWAFNGAKSRYVGSPLLLDDMILAPNADHNLYALDLQGALKWKFEARQALWSQPISDGDVVYLASMDHYLYALALNDGSLKWESDMGGSIVGSPTLADGVLYVGTIGSEVVAVDAETGKDLWRFATTGEVWAQPVVHDGVVFFGDLRGTLYGLDAKTGAQFWKVENAGQVIGAAGILENGVVFATEQSGLKAFGFDGSPLWSLLINGKLYGSPKITDQYILVGVNEGDAIVVAVDFGGNQRWAFQPEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XG07</accession>
    <name>A0A0P6XG07_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_18080</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL69981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18080"/>
    <dbReference type="EnsemblBacteria" id="KPL69981">
        <property type="protein sequence ID" value="KPL69981"/>
        <property type="gene ID" value="ADN00_18080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL69981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="150" mass="16963" checksum="54926D4D9F4313CA" modified="2016-01-20" version="1">MAFLLSSQIFLMVTFFCPNCWTSIPEETEICPHCGYELKQFGSLTYEDKLLAALHHSVPERRIMAAQILGNRGCEQALPIFLDILQSGESNYFLLRAILMAAIKINSPLRLEVLTQASHHDSLLVKKLASEMLTQLNNNQAPQKWDRNTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XG18</accession>
    <name>A0A0P6XG18_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">TsaA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_14440</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the tRNA methyltransferase O family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000034">
        <property type="protein sequence ID" value="KPL73774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063732.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000034.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14440"/>
    <dbReference type="EnsemblBacteria" id="KPL73774">
        <property type="protein sequence ID" value="KPL73774"/>
        <property type="gene ID" value="ADN00_14440"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09281">
        <property type="entry name" value="UPF0066"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023370">
        <property type="entry name" value="TrmO-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023368">
        <property type="entry name" value="UPF0066_cons_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040372">
        <property type="entry name" value="YaeB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036413">
        <property type="entry name" value="YaeB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036414">
        <property type="entry name" value="YaeB_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12818">
        <property type="entry name" value="PTHR12818"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01980">
        <property type="entry name" value="TrmO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118196">
        <property type="entry name" value="SSF118196"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01318">
        <property type="entry name" value="TSAA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51668">
        <property type="entry name" value="TSAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="TsaA-like" evidence="3">
        <location>
            <begin position="6"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00033753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL73774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="155" mass="17906" checksum="8E0495958BE9CD2C" modified="2016-01-20" version="1">METFELKSIGRIRREGEDVAVLIDEAYRPALRDLGHFSHVMVFFWPNRFDEPQMREVLVVDLPYAEGHQSGVFATRSPMRPNPVLMTTCKILGVDEEQGVVRLADMDAFDGTPVLDLKAYFPVCDRVKQAHIPEWLQGWPEWMPEEGIGLEEYER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XG39</accession>
    <name>A0A0P6XG39_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ADN00_18300</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064492.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18300"/>
    <dbReference type="EnsemblBacteria" id="KPL70017">
        <property type="protein sequence ID" value="KPL70017"/>
        <property type="gene ID" value="ADN00_18300"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2967"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031967">
        <property type="entry name" value="PhoR_single_Cache-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16736">
        <property type="entry name" value="sCache_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="166"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="9">
        <location>
            <begin position="191"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="8">
        <location>
            <begin position="248"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="368"/>
            <end position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL70017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="583" mass="65168" checksum="7FAA9C8723BC384D" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XG44</accession>
    <name>A0A0P6XG44_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Lipoate--protein ligase</fullName>
            <ecNumber evidence="4">6.3.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_05135</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(R)-lipoate + ATP + L-lysyl-[lipoyl-carrier protein] = (R)-N(6)-lipoyl-L-lysyl-[lipoyl-carrier protein] + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:49288"/>
            <dbReference type="Rhea" id="RHEA-COMP:10500"/>
            <dbReference type="Rhea" id="RHEA-COMP:10502"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.1.20"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Protein modification; protein lipoylation via exogenous pathway; protein N(6)-(lipoyl)lysine from lipoate: step 1/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; protein lipoylation via exogenous pathway; protein N(6)-(lipoyl)lysine from lipoate: step 2/2.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.1.20" evidence="4"/>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061901.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05135"/>
    <dbReference type="EnsemblBacteria" id="KPL78645">
        <property type="protein sequence ID" value="KPL78645"/>
        <property type="gene ID" value="ADN00_05135"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1499"/>
    <dbReference type="UniPathway" id="UPA00537">
        <property type="reaction ID" value="UER00594"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016979">
        <property type="term" value="F:lipoate-protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004143">
        <property type="entry name" value="BPL_LPL_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019491">
        <property type="entry name" value="Lipoate_protein_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004562">
        <property type="entry name" value="LipoylTrfase_LipoateP_Ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12561">
        <property type="entry name" value="PTHR12561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03099">
        <property type="entry name" value="BPL_LplA_LipB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10437">
        <property type="entry name" value="Lip_prot_lig_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00545">
        <property type="entry name" value="lipoyltrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51733">
        <property type="entry name" value="BPL_LPL_CATALYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BPL/LPL catalytic" evidence="8">
        <location>
            <begin position="27"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL78645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="329" mass="37779" checksum="A5D420F583EB25B8" modified="2016-01-20" version="1">MIFVDNQNTYDPRVNLAIEEHLLRTLDTDEDILLFYINQPSIIIGRNQNTLEEINHEYVEQNGVHVVRRLSGGGAVYHDLGNLNFSFISNYSRDNFKNFKKFTGPVIEVLHSLGVPAELSGRNDILVEGRKISGNAQYTTTRRMYSHGTLLLNTNLEHLVAALNVKMSKIESKGIKSVRSRVANISEYLSEEMDTLTFRQRLLEGIFAGLPTIPEYKLTEADWQAIHKLYEERYSRWDWNFGHSPDFNVKKVERFPFGEVEVRIDVHKGMVEGFKIFGDFQGEGDIHDIESAVIGTRFERESLLQALQNLAVDRYFGGFGAEDFVNFIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XG68</accession>
    <name>A0A0P6XG68_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Adenine deaminase</fullName>
            <shortName evidence="5">Adenase</shortName>
            <shortName evidence="5">Adenine aminase</shortName>
            <ecNumber evidence="3 5">3.5.4.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ade</name>
        <name evidence="8" type="ORF">ADN00_05190</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>adenine + H(+) + H2O = hypoxanthine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:23688"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:17368"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the metallo-dependent hydrolases superfamily. Adenine deaminase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.2" evidence="3 5"/>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061912.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05190"/>
    <dbReference type="EnsemblBacteria" id="KPL78654">
        <property type="protein sequence ID" value="KPL78654"/>
        <property type="gene ID" value="ADN00_05190"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1510"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000034">
        <property type="term" value="F:adenine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006146">
        <property type="term" value="P:adenine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01518">
        <property type="entry name" value="Adenine_deamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006679">
        <property type="entry name" value="Adenine_deam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026912">
        <property type="entry name" value="Adenine_deam_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11113:SF2">
        <property type="entry name" value="PTHR11113:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13382">
        <property type="entry name" value="Adenine_deam_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0464">Manganese</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="6">
        <location>
            <begin position="81"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="domain" description="Adenine_deam_C" evidence="7">
        <location>
            <begin position="426"/>
            <end position="594"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL78654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="611" mass="65086" checksum="C7B63A916096987D" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGB7</accession>
    <name>A0A0P6XGB7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Yip1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_04975</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061849.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79199">
        <property type="protein sequence ID" value="KPL79199"/>
        <property type="gene ID" value="ADN00_04975"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006977">
        <property type="entry name" value="Yip1_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04893">
        <property type="entry name" value="Yip1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="121"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="153"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="208"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="232"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="Yip1" evidence="6">
        <location>
            <begin position="26"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL79199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="267" mass="28296" checksum="EFED918F275745AF" modified="2016-01-20" version="1">MNAETTNAAPTSKMTSLLATTRQYVLKPHEFFSQQVDKPMKRWWILALVILALSLLTILVSNSAEARIAMQEAAAAMPDPSMMGGKGVVVSNGYGGEVYPGPQAAGANGALSALKTAGKLLIIPIGWLAWSVSLYVGTLLSGGRGGFKNVLRMVMLAWLPLALRSVIQTIYILISGQPISNPGLSGLVANPTSIGLTALQALLRYMDVYFIWTLQLLALGISVYGRLPRKKAFILTGACALVLLLVLLLPAFIGQVAGGIQNGMLGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XH29</accession>
    <name>A0A0P6XH29_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_04365</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061733.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04365"/>
    <dbReference type="EnsemblBacteria" id="KPL79102">
        <property type="protein sequence ID" value="KPL79102"/>
        <property type="gene ID" value="ADN00_04365"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="209" mass="22687" checksum="FDAC0E8D2EE76DF1" modified="2016-01-20" version="1">MATNKPADLTAEQIWTVEPGEKRSVGVIHIVILALLIGIGFVVGSFGSISFPLGFGVNFFWTGIAVQQVGSIWFGLWGVLAGAIFPFFSNAIAGTPFYISLAYIPANAVQSFLPAWAFRRFKADPRLRSGRDYLILLAAMIVSSAFGALWSPLVVLRSFGLLTTDSVPLFIWGWFGGNVVAGLVFNFILLKVLSPVVIRTAAFVKKWLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XH84</accession>
    <name>A0A0P6XH84_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Thioredoxin peroxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_04715</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04715"/>
    <dbReference type="EnsemblBacteria" id="KPL79157">
        <property type="protein sequence ID" value="KPL79157"/>
        <property type="gene ID" value="ADN00_04715"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AhpC-TSA" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="105" mass="12301" checksum="2471FE084A748751" modified="2016-01-20" version="1">MSQDHQLFEERGAQILAMGPDGPLGFKRYWAEHEIPFIGMADVKSKMSDRYYQEVNLFKMGRMPAVFVIDRQGMIRYAHYGDSMKDIPENQEILDVIDRLEKEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XHF9</accession>
    <name>A0A0P6XHF9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063580.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000032.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74341">
        <property type="protein sequence ID" value="KPL74341"/>
        <property type="gene ID" value="ADN00_13650"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="157"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="305"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="333"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="367"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="400"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="538" mass="58157" checksum="A22C7BAEAF78673B" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XHI5</accession>
    <name>A0A0P6XHI5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Prephenate/arogenate dehydrogenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_02460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000011">
        <property type="protein sequence ID" value="KPL79565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061374.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000011.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02460"/>
    <dbReference type="EnsemblBacteria" id="KPL79565">
        <property type="protein sequence ID" value="KPL79565"/>
        <property type="gene ID" value="ADN00_02460"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008977">
        <property type="term" value="F:prephenate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004665">
        <property type="term" value="F:prephenate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006571">
        <property type="term" value="P:tyrosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003099">
        <property type="entry name" value="Prephen_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02153">
        <property type="entry name" value="PDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51176">
        <property type="entry name" value="PDH_ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prephenate/arogenate dehydrogenase" evidence="1">
        <location>
            <begin position="9"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="288" mass="30645" checksum="4009DF35812EFDB9" modified="2016-01-20" version="1">MSEKDLSEVDFTLLGLGLMGGSLAAALRGKVRSICAVDPNPTALQFALQRGWIDRGETRPSAQALNSGCVMLAAPVRANLALLPQIAGLLPEGCLLLDLSSTKSEIVQAMQSLPAHIHPIGGHPMCGKESQGVENADPQLFAGRVFFLTPLQRTPPAALLLAHHIVDAIAARPVVVDAAQHDGAVAAVSALPYLLAGSLVRAAQQMAQENPLVWQAAASGYRDTSRLAASDTTMMLDVLLTNPHNVIHALRTCLADLQALTEELENSQQPALAQRLEQAKTIRRNFQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XHM9</accession>
    <name>A0A0P6XHM9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Uridylate kinase</fullName>
            <shortName evidence="10">UK</shortName>
            <ecNumber evidence="10">2.7.4.22</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Uridine monophosphate kinase</fullName>
            <shortName evidence="10">UMP kinase</shortName>
            <shortName evidence="10">UMPK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10 12" type="primary">pyrH</name>
        <name evidence="12" type="ORF">ADN00_03045</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the reversible phosphorylation of UMP to UDP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP + UMP = ADP + UDP</text>
            <dbReference type="Rhea" id="RHEA:24400"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:58223"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.22"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="10">Inhibited by UTP.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Pyrimidine metabolism; CTP biosynthesis via de novo pathway; UDP from UMP (UMPK route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the UMP kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.22" evidence="10"/>
    <dbReference type="EMBL" id="LGCL01000014">
        <property type="protein sequence ID" value="KPL79321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061487.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000014.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03045"/>
    <dbReference type="EnsemblBacteria" id="KPL79321">
        <property type="protein sequence ID" value="KPL79321"/>
        <property type="gene ID" value="ADN00_03045"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2020"/>
    <dbReference type="UniPathway" id="UPA00159">
        <property type="reaction ID" value="UER00275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033862">
        <property type="term" value="F:UMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044210">
        <property type="term" value="P:'de novo' CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04254">
        <property type="entry name" value="AAK_UMPK-PyrH-Ec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01220_B">
        <property type="entry name" value="PyrH_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001057">
        <property type="entry name" value="Glu/AcGlu_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011817">
        <property type="entry name" value="Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015963">
        <property type="entry name" value="Uridylate_kinase_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005650">
        <property type="entry name" value="Uridylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00474">
        <property type="entry name" value="GLU5KINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02075">
        <property type="entry name" value="pyrH_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 10" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AA_kinase" evidence="11">
        <location>
            <begin position="8"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="12"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>UMP</name>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="135"/>
            <end position="142"/>
        </location>
        <ligand>
            <name>UMP</name>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KPL79321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="239" mass="26047" checksum="218B7A54C3A90198" modified="2016-01-20" version="1">MENIKYHRILLKLSGEALAGPQQFGIDPHRALHIAERVREVRELGVDVAIVIGAGNLWRGREGLELGMDRATADYMGMLATVMNALALMDSLESLGVVTRVQSAVEMRSVAEPYIRRRAIRHLEKGRVVIFGGGTGNPYFSTDTAAALRAMEIGADVLIKATKVDGVYDSDPKKNPNAVKFDHLTYIDTLNRQLKVMDSTAISLCMENQLPILVLDLFDESALRGALVGQSVGTLVTAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XHV2</accession>
    <name>A0A0P6XHV2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_02775</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000013">
        <property type="protein sequence ID" value="KPL79404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061470.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000013.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02775"/>
    <dbReference type="EnsemblBacteria" id="KPL79404">
        <property type="protein sequence ID" value="KPL79404"/>
        <property type="gene ID" value="ADN00_02775"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2188"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037522">
        <property type="entry name" value="HD_GYP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51832">
        <property type="entry name" value="HD_GYP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="2"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="HD-GYP" evidence="3">
        <location>
            <begin position="122"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL79404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="333" mass="37485" checksum="E575CB363513F9E6" modified="2016-01-20" version="1">MRILIVDDDIIAQAAAKKILETHGHQTVLAENGEEALEILKQDTIQVVISDWNMPVMDGIELCKRIRQNSPLGYVYFILVTVRSSKEDLLTGLSAGADDFVTKPFEPAELSLRVRNAERVLALETTTLTLLSLAKLAESKDTDTGNHLERIREYAFLLSSQVINAPDFHDNIPPRFAELMYQTSPLHDIGKVGIPDYVLLKPGSLNDEEWQIMKQHAELGAQTLDAVFIQHPYAEFLRIARDIAWAHHERWDGSGYPRGLKGEEIPLCARIVALADVYDALTMKRVYKAAMPHQVARGIILEGSGKHFDPQVVRAFLAVEDQFIAVQHKFREQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XJI6</accession>
    <name>A0A0P6XJI6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Flagellar basal body protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_17140</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the flagella basal body rod proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064273.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17140"/>
    <dbReference type="EnsemblBacteria" id="KPL71416">
        <property type="protein sequence ID" value="KPL71416"/>
        <property type="gene ID" value="ADN00_17140"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.490"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001444">
        <property type="entry name" value="Flag_bb_rod_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020013">
        <property type="entry name" value="Flagellar_FlgE/F/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010930">
        <property type="entry name" value="Flg_bb/hook_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037925">
        <property type="entry name" value="FlgE/F/G-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00460">
        <property type="entry name" value="Flg_bb_rod"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06429">
        <property type="entry name" value="Flg_bbr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117143">
        <property type="entry name" value="SSF117143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03506">
        <property type="entry name" value="FlgEFG_subfam"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flg_bb_rod" evidence="3">
        <location>
            <begin position="23"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="domain" description="Flg_bbr_C" evidence="4">
        <location>
            <begin position="166"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL71416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="246" mass="27452" checksum="D03434DF4ACF1814" modified="2016-01-20" version="1">MASNLFHTLNISRQDMYARLMELDDVSNNLANINTIGYKRSRLNFQELLDRGFREGNYIASTQVMTEQGAIRNSDNPMDVAISGEGFFAVELGDGEVGYSRNGQFQVDADNNLVNSAGYPIVWDGDIPDGVEEIHFTQDGSVMARQGETWTIVGQLELYRFDNPTALTRKGENIWLESEISGEAQAGQPGVEGMGQIVPRALEQSNVDLSYEVTRMITLQRAFEMSTRTFQQTDEMISGAINMRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XK58</accession>
    <name>A0A0P6XK58_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein-tyrosine-phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.48</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_01555</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein-tyrosine phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.48" evidence="2"/>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01555"/>
    <dbReference type="EnsemblBacteria" id="KPL80556">
        <property type="protein sequence ID" value="KPL80556"/>
        <property type="gene ID" value="ADN00_01555"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016311">
        <property type="term" value="P:dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022778">
        <property type="entry name" value="CDKN3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05706">
        <property type="entry name" value="CDKN3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="SSF52799"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00383">
        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TYR_PHOSPHATASE_2" evidence="3">
        <location>
            <begin position="97"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL80556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="174" mass="19267" checksum="FEA2FC21F709FF8A" modified="2016-01-20" version="1">MSDFPPPVPLPASYWVEPGRFLAGEYPASRYFDEQTRTTLGSLLDAGITCFINLTEDGELPPYEKILQEQAGWRGVEVNTHHFPIQNYGLPTRAQMKEILNALDEALASGQSVYLHCWGGIGRTGTVVGCWLVRHGLSGQAALKRIQSLRLAVPGGYASPETDAQVEFVEFWKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XK72</accession>
    <name>A0A0P6XK72_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01705</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061230.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80583">
        <property type="protein sequence ID" value="KPL80583"/>
        <property type="gene ID" value="ADN00_01705"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011397">
        <property type="entry name" value="YhfC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10086">
        <property type="entry name" value="YhfC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="128" mass="13743" checksum="9C63028949842A40" modified="2016-01-20" version="1">MLEFTFLLAILIEWAVPFVLAFLIARRYRAAWGLFWVGALAFAASQIVHIPLNLGISALFRNGLIPAPTPEAAIAVNAVLAGTTAALCETPARLIALRLLKERGRDWGSALMVGAGHGGIEFSLWGCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKH8</accession>
    <name>A0A0P6XKH8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Site-specific DNA-methyltransferase (cytosine-N(4)-specific)</fullName>
            <ecNumber evidence="3">2.1.1.113</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_12875</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxycytidine in DNA + S-adenosyl-L-methionine = an N(4)-methyl-2'-deoxycytidine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:16857"/>
            <dbReference type="Rhea" id="RHEA-COMP:11369"/>
            <dbReference type="Rhea" id="RHEA-COMP:13674"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:85452"/>
            <dbReference type="ChEBI" id="CHEBI:137933"/>
            <dbReference type="EC" id="2.1.1.113"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the N(4)/N(6)-methyltransferase family. N(4) subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.113" evidence="3"/>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063426.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000027.1"/>
    </dbReference>
    <dbReference type="REBASE" id="132872">
        <property type="entry name" value="M.OapP3M1ORF12875P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL75529">
        <property type="protein sequence ID" value="KPL75529"/>
        <property type="gene ID" value="ADN00_12875"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1271"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015667">
        <property type="term" value="F:site-specific DNA-methyltransferase (cytosine-N4-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002941">
        <property type="entry name" value="DNA_methylase_N4/N6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017985">
        <property type="entry name" value="MeTrfase_CN4_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01555">
        <property type="entry name" value="N6_N4_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00093">
        <property type="entry name" value="N4_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N6_N4_Mtase" evidence="7">
        <location>
            <begin position="2"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL75529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="349" mass="39125" checksum="D8F8F2D5599E1E75" modified="2016-01-20" version="1">MFPLEFPLEILGTMAHRGDTVLDPFCGRGTTNFAARLLGLDSLGVDSSPVAVAISAAKLVTVSPEDILAEARVIINTQYTFSIPEGDFWNWAYHSDVLRALCHFRAAFLNNCTSPARIALRGIILGALHGPKQKTFPSYFSNQCPRTYAPKPAYSIRFWKERGLYPEPIDVMGVIERRAKRYYKPLPGVSGYVKLADSRNRGSLEPLEKGSLFRWVITSPPYYGMRTYIPDQWLRNWFVGGPDIVDYTNENQLAHSGAEKFSDDLKKVWKNTSLVCANDATMVIRFGGISDRRTSPIDLITKSIQNSGWKITKIVNAGSASEGKRQANAFLRTVTEPLTEYDIWTSRDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-12-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKQ4</accession>
    <name>A0A0P6XKQ4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000003">
        <property type="protein sequence ID" value="KPL80812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061111.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000003.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80812">
        <property type="protein sequence ID" value="KPL80812"/>
        <property type="gene ID" value="ADN00_01055"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1955"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043715">
        <property type="entry name" value="DUF5656"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18900">
        <property type="entry name" value="DUF5656"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="166"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="223"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="251"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="269" mass="29817" checksum="7F3A839869311F00" modified="2016-01-20" version="1">MNERQHLPDANRLSILASTILLAYAISPYVNIPPRSFGVTLFGAVYSLNFDFGLLLSLLVSMLAAVGADWLIRDHPELRETNTMQHWILPALTAWVLGVPLRNLQPGLEWWVVFAFGGILLILVFVAEYIVVDLADDLHAPAAIGLTAVSFALYLFLAISLRAAGLRLYTMLPTIVLSMALVALRTLYLRLNGRWCLVWGVAIAVIVGQFAVGFHYWPLSPLSFGLLLVGPSYALTSTAVLIEEKRPWQTLWIEPVVMLAIFWGMAVMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XL23</accession>
    <name>A0A0P6XL23_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_09810</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062823.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76888">
        <property type="protein sequence ID" value="KPL76888"/>
        <property type="gene ID" value="ADN00_09810"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="26"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL76888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="96" mass="10654" checksum="4F2646D87D86DA55" modified="2016-01-20" version="1">MSNISQEPEQDVPINPTTPKKTIKPVIFISVVIIIWILLCMGSVAFLTIASLCKVMAEKAPIESVLDSFMKSMQVKDTDRAYTFFLCALKTADTLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XLK2</accession>
    <name>A0A0P6XLK2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_11670</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063194.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11670"/>
    <dbReference type="EnsemblBacteria" id="KPL76014">
        <property type="protein sequence ID" value="KPL76014"/>
        <property type="gene ID" value="ADN00_11670"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="15"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL76014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="326" mass="36788" checksum="9A5ACCE3DB5CAC42" modified="2016-01-20" version="1">MPIPLMAGEVLRDRYEIERIIGQGGMGSIYLANDLRLKGRQCALKEVEHERSLSPDLLEEARKQFFQEATVLARLDHPNLPKVSDFFSIQSRDYLVMDFIPGKDLRTLMLEARQQNRFLDETQVLNWASQLADAIAFLHSQEPPILHRDIKPSNLKVTPSGLVKLVDFGLVKVLAPGEVTITILQGQGTALYTPIEQYGGDGGHTDIRSDIFSFGATLYHLLTNHPPADARDRFLDPDALLPPRQINPDISSQTERAILWAMNIHPDDRPNSIQELQQVLFGDRPTLPRSITRSPSFWRTAKREPEKLLWAVVASLSLISFLITVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XLL9</accession>
    <name>A0A0P6XLL9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_11845</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063226.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76041">
        <property type="protein sequence ID" value="KPL76041"/>
        <property type="gene ID" value="ADN00_11845"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="105" mass="12143" checksum="032F13E2F6F3B5D0" modified="2016-01-20" version="1">MYDAFENKSKIFTHVITKEPVDVIVQTTQFKIIGQIHVRPEDRLKDELDQPETFLPVTSAAVHSLDGTELYRTHFIAVNRSQIVWIIPIQQLQPHENPEEEHGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XLU2</accession>
    <name>A0A0P6XLU2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">DNA-directed RNA polymerase subunit alpha</fullName>
            <shortName evidence="11">RNAP subunit alpha</shortName>
            <ecNumber evidence="2 11">2.7.7.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">RNA polymerase subunit alpha</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9 11">Transcriptase subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">rpoA</name>
        <name evidence="13" type="ORF">ADN00_12470</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8 11">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homodimer. The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.</text>
    </comment>
    <comment type="domain">
        <text evidence="11">The N-terminal domain is essential for RNAP assembly and basal transcription, whereas the C-terminal domain is involved in interaction with transcriptional regulators and with upstream promoter elements.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the RNA polymerase alpha chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="2 11"/>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063344.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12470"/>
    <dbReference type="EnsemblBacteria" id="KPL76142">
        <property type="protein sequence ID" value="KPL76142"/>
        <property type="gene ID" value="ADN00_12470"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3975"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.120.12">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00059">
        <property type="entry name" value="RNApol_bact_RpoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011262">
        <property type="entry name" value="DNA-dir_RNA_pol_insert"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011263">
        <property type="entry name" value="DNA-dir_RNA_pol_RpoA/D/Rpb3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011773">
        <property type="entry name" value="DNA-dir_RpoA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036603">
        <property type="entry name" value="RBP11-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011260">
        <property type="entry name" value="RNAP_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036643">
        <property type="entry name" value="RNApol_insert_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32108">
        <property type="entry name" value="PTHR32108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01000">
        <property type="entry name" value="RNA_pol_A_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03118">
        <property type="entry name" value="RNA_pol_A_CTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01193">
        <property type="entry name" value="RNA_pol_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00662">
        <property type="entry name" value="RPOLD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55257">
        <property type="entry name" value="SSF55257"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56553">
        <property type="entry name" value="SSF56553"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02027">
        <property type="entry name" value="rpoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11 13" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="6 11" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0804">Transcription</keyword>
    <keyword evidence="5 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RPOLD" evidence="12">
        <location>
            <begin position="15"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Alpha N-terminal domain (alpha-NTD)" evidence="11">
        <location>
            <begin position="1"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Alpha C-terminal domain (alpha-CTD)" evidence="11">
        <location>
            <begin position="241"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00032524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00033070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KPL76142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="315" mass="35190" checksum="EC61AC5B0C9A6F1E" modified="2016-01-20" version="1">MVMPKIEREAEARNYGKFVIGPLERGYGVTIGNALRRVLLSSLEGAAVTSVRFTDVLHEFSDIPGVREDVIQVMLRIKQLRMILHDVDQAHLHLDVRGEGVVTAADIQCPAEVEITNPELYLFTVDDPTARLDLDMVVERGRGYSPANERTGRLPIGELPVDAIYSPIKRVNWTVGSARVGQSTNYDKLTLEIWTDGTVSPEKSLSTASVILIDHLRYISGVNEEMLMVKKEVEVTGSRLTSEAIDTPIEHLDLSVRVFNSLKRTGITTVGNVIELLEKGDEAVMSIRNFGEKSLDELRDKMREKGFLRDETDTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XMF3</accession>
    <name>A0A0P6XMF3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MFS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_00340</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060965.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL81028">
        <property type="protein sequence ID" value="KPL81028"/>
        <property type="gene ID" value="ADN00_00340"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="178"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="219"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="253"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="294"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="327"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="360"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="384"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="418"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="453"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="1"/>
            <end position="480"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL81028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="480" mass="51145" checksum="0954572FF7D78F2D" modified="2016-01-20" version="1">MERPLRWFDTITINIYFLGLSALSQTMAPLILPLLVQQFVGENLKGTYYGNLRLWSLMMALLVQSLMGMLSDRHQSKYGKRRPFIFIGTLGVILVVLLIGFVAGMEGLTGYWVLFGLVILQQVGANTGHGAVQGLIPDLVPENMRGRYSAIKAILEVPLPVILVSMTIGKLVGAGNLWAGLFVLIAILLVAMIIAMFAPEKSSLDSNALSLDWKPFLRLVSMTALFTAIILGMGELIKWLSAFLAFTSDFLNLATISVVGFLAMALAIAVGVSASTRLGIGDANAHKSAFNWWVINRLAFLVGSTGMVSFMVYFLQGKFGFVAEQAAAPAAQLTMIVGVFILLSALPSGWLTDRFGSRKIVAAAGLMAALGTVLVIFAPDLTTVFIGGSFIGIGTGFFYSANWALGTEIAPKEEAGRYLGISNLAGAGAGAVGAYIGGPIADYFTVLVPQTPGLGYVALFAIYGILFLLSVACLRSVKQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XMJ1</accession>
    <name>A0A0P6XMJ1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ABC2_membrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_00590</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061010.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00590"/>
    <dbReference type="EnsemblBacteria" id="KPL81064">
        <property type="protein sequence ID" value="KPL81064"/>
        <property type="gene ID" value="ADN00_00590"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="102"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="165"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="215"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="6">
        <location>
            <begin position="3"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL81064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="240" mass="26632" checksum="1195823CA69F1A82" modified="2016-01-20" version="1">MRNLWIITRKEYRHYFNSPIAYAVAFMVLLVTGIIFYASIARAAMQATVPEPRSILTPMISLFLFTTPAITMGLLSEEQKTGTIELLMTAPLRTVDIIIGKWLASFLFLSTIAAIPVIFLVYLNFLVDPGIDWGISISGYLGMFLLISSFTAIGVAASSFFSNQIASFFAAFAIIMALWLLDVPAQTGPEFLKALDLGEHFYNSFYQGVIKGTDIIYYLSVTAVSLFAGVTSLESRRWRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XMJ4</accession>
    <name>A0A0P6XMJ4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">2-hydroxyhepta-2,4-diene-1,7-dioate isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_19130</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064640.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_19130"/>
    <dbReference type="EnsemblBacteria" id="KPL70147">
        <property type="protein sequence ID" value="KPL70147"/>
        <property type="gene ID" value="ADN00_19130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.850.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018833">
        <property type="entry name" value="DUF2437"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011234">
        <property type="entry name" value="Fumarylacetoacetase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036663">
        <property type="entry name" value="Fumarylacetoacetase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10370">
        <property type="entry name" value="DUF2437"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01557">
        <property type="entry name" value="FAA_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56529">
        <property type="entry name" value="SSF56529"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2437" evidence="2">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="FAA_hydrolase" evidence="1">
        <location>
            <begin position="56"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL70147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="258" mass="28718" checksum="5A6D97D6572E228F" modified="2016-01-20" version="1">MRFLRYQFENNPPQYGWLHEGQVGPLDGSPFEGYRRQEATIALEQVRLLPPVIPQKIVCVGRNYADHAREQDAEIPEIPLLFLKPPSSIIAHQASIYLPPQSHQVDHEAELAVVIGRTCRWVSSETALSFVFGYTIANDVTARDLQRKDGQWTRAKGFDTFCPLGPWIETDFDPADALITCRVNEELRQMSSTREMIFTISQLIAFVSSIMTLEPGDLLLTGTPAGVGPLQPGDRVDISIEGIGSLQNPVRSSPSIFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XMQ9</accession>
    <name>A0A0P6XMQ9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">(2Fe-2S)-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_00270</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00270"/>
    <dbReference type="EnsemblBacteria" id="KPL81137">
        <property type="protein sequence ID" value="KPL81137"/>
        <property type="gene ID" value="ADN00_00270"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3447"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002888">
        <property type="entry name" value="2Fe-2S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036884">
        <property type="entry name" value="2Fe-2S-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00111">
        <property type="entry name" value="Fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01799">
        <property type="entry name" value="Fer2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47741">
        <property type="entry name" value="SSF47741"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="2">
        <location>
            <begin position="10"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL81137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="165" mass="17619" checksum="E89EA347978C7656" modified="2016-01-20" version="1">MPEKVEYPGGVIQTRVNGKDYTLQSGFEKTLLRLLREDVGLTGTKEGCAEGECGACTVILDGKAVMSCMVPAARAHMAEIRTVEGLANEAGLHPVQEAFVEAGAVQCGYCTPGFLMSAAVLLEELPQPSKDQIKQAFTGNLCRCTGYYSIIDAVERTITRKAEGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XMU2</accession>
    <name>A0A0P6XMU2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_11315</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063123.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76544">
        <property type="protein sequence ID" value="KPL76544"/>
        <property type="gene ID" value="ADN00_11315"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="135" mass="15414" checksum="7141E69F56E0E79A" modified="2016-01-20" version="1">MIDTIVRSFLGKWGSAALDFYLANSAWINLIILFYALALIWSQRTYKQILTQIILDLVKDFGPEVADKKPEALAKILKKRKFSWESLAALNRFPLVAPPRSYWFHTKNEKSLQSLFSPEKLAKAVAEQLQSAKGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQ30</accession>
    <name>A0A0P6XQ30_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CheX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_17315</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71445.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064306.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17315"/>
    <dbReference type="EnsemblBacteria" id="KPL71445">
        <property type="protein sequence ID" value="KPL71445"/>
        <property type="gene ID" value="ADN00_17315"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028976">
        <property type="entry name" value="CheC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038756">
        <property type="entry name" value="CheX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028051">
        <property type="entry name" value="CheX-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39452">
        <property type="entry name" value="PTHR39452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13690">
        <property type="entry name" value="CheX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103039">
        <property type="entry name" value="SSF103039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CheX" evidence="2">
        <location>
            <begin position="42"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL71445.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="171" mass="18451" checksum="46EDAFCDBF1E4DC1" modified="2016-01-20" version="1">MNVKFLNPFLEATAEVVKTETGYDLKRGDLKLEEKPYSTGEVTTIIAMVGGVEGNVFISMSRDTALQLATRMMREKFDEFDGLAQSGIAELGNVITGRASVKLSATGYEATISPPTMLMGAGAVISTLDFHRLVVPFYAECGEIVIHLALREGRSSAVNAAQIPVPRRPSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQI7</accession>
    <name>A0A0P6XQI7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_03940</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061662.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79046">
        <property type="protein sequence ID" value="KPL79046"/>
        <property type="gene ID" value="ADN00_03940"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.143"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="189"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="224"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="8"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="157"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="307" mass="32872" checksum="2C069E2FD039B1BF" modified="2016-01-20" version="1">MKRFKTAMIPVFLLAVLLGSNTVIARAAMQSVSPYALNAARVSLTALIYLISFALIPGWRWPRDLSVWLQAGLWGIFGFALPLTAFMHVLTYFSSGVTSLFGTLSPVVVAILAHFLLQDERLTLLKIAGSLIAFGGVAIILFSGETGLGGLVQADPRGYLWAAVGVLSGSGSVVYSRRFLSNMESIQATGIRTVVAAPILIAVAIFTGNFQFQPLLHGGNLLGLIYLASIGTFVIFILEFHVIQSFGAGPASQMNYLLPPIATGLGVLFLGEQISLVFVTGMLVIFIGLFLVNYTPRPQPTPDPQIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQK0</accession>
    <name>A0A0P6XQK0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HlyD_D23 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_04065</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061683.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04065"/>
    <dbReference type="EnsemblBacteria" id="KPL79064">
        <property type="protein sequence ID" value="KPL79064"/>
        <property type="gene ID" value="ADN00_04065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="3">
        <location>
            <begin position="270"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL79064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="468" mass="51102" checksum="BA8A1FF14ADF8BDD" modified="2016-01-20" version="1">MKKRVFWIIGIGIVAVVGFLIFNNIQKARQAMNEAFQTAQVERGELVAIVGATGTVRANQSAVLTWQTSGRIDEITVQVDEAVRADQVLAELAKDSLPQNVILAEAELVEARRALENLKDSNLTSAQAALTLAQAQQAYEDAMEDRQSQSFGRASQNTIDGLRAEYVLAKNALDDAETFFTAFEDRAEDDPNRAEALSVLVNARKRADRALANLNYALGMPDSNEVAEAEARVTLAKAQLEDAQREWERLKDGADPEDIAAAEARVAAVEASLNYRYLKAPFEGTVTEVNSKEGDQVSPGTASIRVDDLARMLVEVRIPEVDINRVVIGDEVRMSFDAIRDQEYLGKVTEIARVGTTTQSGVDFAVTIELVDMDPQVRPGMTAAVNIVVEKLENVLLVPNRAVRFRDGKRVVYVQNATGMLDAVDVQIGSSSELYSEIIGGELKEGDVVVLNPPAEFQPPQGGPMNRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQP0</accession>
    <name>A0A0P6XQP0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_04415</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061743.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04415"/>
    <dbReference type="EnsemblBacteria" id="KPL79110">
        <property type="protein sequence ID" value="KPL79110"/>
        <property type="gene ID" value="ADN00_04415"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.239"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="14"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="47"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="70"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="146"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="205"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="240"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="278"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL79110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="319" mass="33633" checksum="B05E3FBD53C3D0E6" modified="2016-01-20" version="1">MLNDLLSIFASPEFYQAVLRMATPLLLAAMGGLVAERAGLVTFSMEGMMLMGAVGGVIGSHLTGSVWGGLLLAVIFGMLAGLTYAVMAVSIGAHQIVTCVALNMGAMGLTSVLFGLVFGGGSGAVVQDVIQVASLSPWKIPLLGEIPILGPIFFNHIPLVYLAFLTVPAVWFLLYRTTWGLKIRAVGEHPHAADALGISVVRVRYLTLLFAGAFAGLAGAFLSIGVLNTWQENMTSGRGFIAYTAIVFGKWQPLGVLLGALLFGLADALQLRVQTMNIAIPYQAMVAFPYVVTLLALILFSGKASWPAASGQAFKREGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XR58</accession>
    <name>A0A0P6XR58_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_16625</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064163.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72094">
        <property type="protein sequence ID" value="KPL72094"/>
        <property type="gene ID" value="ADN00_16625"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3768"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="5"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="292"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL72094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="531" mass="59560" checksum="57CC4EAEE4B20790" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XR65</accession>
    <name>A0A0P6XR65_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TIR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_13440</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13440"/>
    <dbReference type="EnsemblBacteria" id="KPL74836">
        <property type="protein sequence ID" value="KPL74836"/>
        <property type="gene ID" value="ADN00_13440"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1175"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003953">
        <property type="term" value="F:NAD+ nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019677">
        <property type="term" value="P:NAD catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="G-protein_beta_WD-40_rep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000157">
        <property type="entry name" value="TIR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035897">
        <property type="entry name" value="Toll_tir_struct_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13676">
        <property type="entry name" value="TIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="SSF50978"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52200">
        <property type="entry name" value="SSF52200"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50104">
        <property type="entry name" value="TIR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="667"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="domain" description="TIR" evidence="6">
        <location>
            <begin position="24"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="781"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="824"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="926"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="957"/>
            <end position="998"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1000"/>
            <end position="1041"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1043"/>
            <end position="1077"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1086"/>
            <end position="1127"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1129"/>
            <end position="1170"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1172"/>
            <end position="1213"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1301"/>
            <end position="1342"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1344"/>
            <end position="1378"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="621"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="693"/>
            <end position="727"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL74836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="1565" mass="171332" checksum="902067DF7363E3B3" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XR98</accession>
    <name>A0A0P6XR98_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3 4">Single-stranded DNA-binding protein</fullName>
            <shortName evidence="2">SSB</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_15090</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063867.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15090"/>
    <dbReference type="EnsemblBacteria" id="KPL72158">
        <property type="protein sequence ID" value="KPL72158"/>
        <property type="gene ID" value="ADN00_15090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.720"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04496">
        <property type="entry name" value="SSB_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00984">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000424">
        <property type="entry name" value="Primosome_PriB/ssb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011344">
        <property type="entry name" value="ssDNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10302">
        <property type="entry name" value="PTHR10302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00436">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002070">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00621">
        <property type="entry name" value="ssb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50935">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR002070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL72158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="133" mass="15078" checksum="2544BCECD92948F9" modified="2016-01-20" version="1">MTRGLNKVMIIGYLGRDPEMRYTPSGRPVTTFSVGTSRTWTTAEGDRRSETEWFNVVTWGNLAEICKQYLSKGQQVYIDGRLQTRRWEDTSGAKHTTVEIVANEMMMLGDRPDSGASHADAAFETNEEDTFPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XRM2</accession>
    <name>A0A0P6XRM2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_02690</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000012">
        <property type="protein sequence ID" value="KPL79439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061418.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000012.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02690"/>
    <dbReference type="EnsemblBacteria" id="KPL79439">
        <property type="protein sequence ID" value="KPL79439"/>
        <property type="gene ID" value="ADN00_02690"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001667">
        <property type="entry name" value="DDH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038763">
        <property type="entry name" value="DHH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003156">
        <property type="entry name" value="DHHA1_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01368">
        <property type="entry name" value="DHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02272">
        <property type="entry name" value="DHHA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64182">
        <property type="entry name" value="SSF64182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHH" evidence="1">
        <location>
            <begin position="20"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="DHHA1" evidence="2">
        <location>
            <begin position="234"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="323" mass="35100" checksum="48A1EB5F6BE448B2" modified="2016-01-20" version="1">MKNEALHRSIRDRLHNANSVVITSHIRPDGDAVGSVVGLGLSLSLAGKQVQMVLADRVSAQLRFIPGAELVTTHAEQTFDLSIVVDCSDLERTGAVLGEQKPDLNIDHHITNLNFANLNLVDISSVSTTALIARHLRADWDLPMDEKVATALLSGIVTDTIGFRTSNMTSEALRIAANLMDEGAELSDIYQRAITYRSYEAVRFWGKGIARMQRKGRLVWTALTNEDRRSAAYQGKDDADLINIISSIEDNDVSIIFTEKDENKVKVSWRAQPGIDVSQIALAFGGGGHPAASGAEITGSLEEVQEKVLDATKAILNGKNKEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XSZ5</accession>
    <name>A0A0P6XSZ5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Trk system potassium uptake protein TrkA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_12145</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063284.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12145"/>
    <dbReference type="EnsemblBacteria" id="KPL76088">
        <property type="protein sequence ID" value="KPL76088"/>
        <property type="gene ID" value="ADN00_12145"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015079">
        <property type="term" value="F:potassium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006036">
        <property type="entry name" value="K_uptake_TrkA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02080">
        <property type="entry name" value="TrkA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02254">
        <property type="entry name" value="TrkA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00335">
        <property type="entry name" value="KUPTAKETRKA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51201">
        <property type="entry name" value="RCK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4" id="KW-0520">NAD</keyword>
    <keyword evidence="3" id="KW-0630">Potassium</keyword>
    <keyword evidence="2" id="KW-0633">Potassium transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="RCK N-terminal" evidence="5">
        <location>
            <begin position="2"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="6">
        <location>
            <begin position="136"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00017378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL76088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="215" mass="23481" checksum="CB25F0F05A170BA8" modified="2016-01-20" version="1">MKILIIGCGRVGANLSHILSMRGHDLTIVDKDPEAFRELGTWFKGKTYVGIGFDKQLLLEAGIERADGLAAVTLSDEANVVVARLAQQFFRVPRVAARVYDPRKAEIYRRLGLQTISPVTIGSLRLAELLSFNQLTPVATLGSGEVEIVQAEINTFLVGHPVRDLVIAGQIKVVSITRRGKTFLPDQSTAFEKGDIVQIATTISAADRLAKMLEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XSZ8</accession>
    <name>A0A0P6XSZ8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_12205</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063294.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76097">
        <property type="protein sequence ID" value="KPL76097"/>
        <property type="gene ID" value="ADN00_12205"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="SSF54106"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133205" evidence="2">
        <location>
            <begin position="31"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="3">
        <location>
            <begin position="82"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="3">
        <location>
            <begin position="153"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="214"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL76097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="228" mass="24419" checksum="C426DFACC43E12B2" modified="2016-01-20" version="1">MKIVQQVVAGFLVACVSLGLVIGAFSAAFAESAVFSTATLESSPEPTQPAPAYIPLPTRTPTKQPPPTLTPTIACLPPEGWQKYETQSGDTIEELAARFAITKEQIRAANCLISDQILPNTELYLPRVPATLTPSATINPTATPGCGAPAGWITYTVRLNDNLFRIGYNFGISVQELQTANCLGNTQIIRPGQVLYVPNVATRTPLPSATPVEEDDDEDKKPTLPPYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XT20</accession>
    <name>A0A0P6XT20_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_07230</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78254">
        <property type="protein sequence ID" value="KPL78254"/>
        <property type="gene ID" value="ADN00_07230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="73" mass="8169" checksum="05B9E1FCDB820981" modified="2016-01-20" version="1">MGVIIINDLLTEMFTDVQVWIIMPDEQAGAWDRVSFHVYLLPVLQAKSCQWAARQAASTKKEGMEEVFNGIGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XTC8</accession>
    <name>A0A0P6XTC8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_07755</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78336">
        <property type="protein sequence ID" value="KPL78336"/>
        <property type="gene ID" value="ADN00_07755"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="23"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="98"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="129"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="247"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="284"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="381"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="461"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="495"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="521"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="579"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="644"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="683"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="94"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="455"/>
            <end position="662"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL78336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="1168" mass="126872" checksum="34F86DA4BBA22BD8" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XTZ9</accession>
    <name>A0A0P6XTZ9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">TsaD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01875</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000007">
        <property type="protein sequence ID" value="KPL80043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061266.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000007.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01875"/>
    <dbReference type="EnsemblBacteria" id="KPL80043">
        <property type="protein sequence ID" value="KPL80043"/>
        <property type="gene ID" value="ADN00_01875"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2301"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000905">
        <property type="entry name" value="Gcp-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022496">
        <property type="entry name" value="T6A_TsaB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735">
        <property type="entry name" value="PTHR11735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735:SF11">
        <property type="entry name" value="PTHR11735:SF11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00814">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03725">
        <property type="entry name" value="T6A_YeaZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TsaD" evidence="1">
        <location>
            <begin position="31"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="226" mass="24577" checksum="C5E375CED59B0F90" modified="2016-01-20" version="1">MLLAVDTSTQWTGLALYEENQVVGEMIWNTRNHHTVEMAPAIRSLLNRCGVETQDLKALAVALGPGSFTSLRIGLAVAKGMALALHIPMIGIPTLDFLAAAQPGSEDPLACILRAGRGRFALQWYGFMKGKWRAQGDLQVIEKANLAEAFPPHKALVAGELSALERQSLARKCKQLELADPARSARRPAYLAQLAWARYEAKQFDEPVSLAPIYLHVVPGSVPAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUC5</accession>
    <name>A0A0P6XUC5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Polyamine aminopropyltransferase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Putrescine aminopropyltransferase</fullName>
            <shortName evidence="3">PAPT</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Spermidine synthase</fullName>
            <shortName evidence="3">SPDS</shortName>
            <shortName evidence="3">SPDSY</shortName>
            <ecNumber evidence="3">2.5.1.16</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">speE</name>
        <name evidence="6" type="ORF">ADN00_10365</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the irreversible transfer of a propylamine group from the amino donor S-adenosylmethioninamine (decarboxy-AdoMet) to putrescine (1,4-diaminobutane) to yield spermidine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>putrescine + S-adenosyl 3-(methylsulfanyl)propylamine = H(+) + S-methyl-5'-thioadenosine + spermidine</text>
            <dbReference type="Rhea" id="RHEA:12721"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:57443"/>
            <dbReference type="ChEBI" id="CHEBI:57834"/>
            <dbReference type="ChEBI" id="CHEBI:326268"/>
            <dbReference type="EC" id="2.5.1.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amine and polyamine biosynthesis; spermidine biosynthesis; spermidine from putrescine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer or homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the spermidine/spermine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.16" evidence="3"/>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062928.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10365"/>
    <dbReference type="EnsemblBacteria" id="KPL76975">
        <property type="protein sequence ID" value="KPL76975"/>
        <property type="gene ID" value="ADN00_10365"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2539"/>
    <dbReference type="UniPathway" id="UPA00248">
        <property type="reaction ID" value="UER00314"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004766">
        <property type="term" value="F:spermidine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008295">
        <property type="term" value="P:spermidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.140.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00198">
        <property type="entry name" value="Spermidine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030374">
        <property type="entry name" value="PABS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001045">
        <property type="entry name" value="Spermi_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035246">
        <property type="entry name" value="Spermidine_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037163">
        <property type="entry name" value="Spermidine_synt_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11558">
        <property type="entry name" value="PTHR11558"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17284">
        <property type="entry name" value="Spermine_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00417">
        <property type="entry name" value="speE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51006">
        <property type="entry name" value="PABS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0745">Spermidine biosynthesis</keyword>
    <keyword evidence="1 3 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PABS" evidence="5">
        <location>
            <begin position="3"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-methyl-5'-thioadenosine binding" evidence="3">
        <location>
            <begin position="138"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3 4">
        <location>
            <position position="156"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>S-methyl-5'-thioadenosine</name>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>spermidine</name>
            <dbReference type="ChEBI" id="CHEBI:57834"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>spermidine</name>
            <dbReference type="ChEBI" id="CHEBI:57834"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>S-methyl-5'-thioadenosine</name>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL76975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="273" mass="31421" checksum="BA102E1C3DC7AFDF" modified="2016-01-20" version="1">MTEQWFNEELHPWYRKSLKVLEVLEDEQTDFQHLQIVRTEFFGKALILDGIIQLTERDNMGYHEMITHVPMLAVDNPETVLIVGGGDGGTLQQVLKHASVKKVVMSELDRRVVELSRKHFTEFAPAFDDPRFELVIEDAFTYMQRNQAVFDVIISDTTDPIGMAERLFSEEFYELMKHALKPGGAVSTQCEQMYFDTQLIKDILAVAKRLTQNPAYYYSLVPTYPGGGIGFMYMSDTPWSNGLGKTYPQGLNYLNPEMHRAAFALPEFFRREL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUD5</accession>
    <name>A0A0P6XUD5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_05835</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062030.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05835"/>
    <dbReference type="EnsemblBacteria" id="KPL78757">
        <property type="protein sequence ID" value="KPL78757"/>
        <property type="gene ID" value="ADN00_05835"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1643"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008887">
        <property type="term" value="F:glycerate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1480.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037035">
        <property type="entry name" value="GK-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038614">
        <property type="entry name" value="GK_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007835">
        <property type="entry name" value="MOFRL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025286">
        <property type="entry name" value="MOFRL_assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039760">
        <property type="entry name" value="MOFRL_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12227">
        <property type="entry name" value="PTHR12227"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13660">
        <property type="entry name" value="DUF4147"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05161">
        <property type="entry name" value="MOFRL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4147" evidence="2">
        <location>
            <begin position="21"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="MOFRL" evidence="1">
        <location>
            <begin position="345"/>
            <end position="451"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="458" mass="47944" checksum="B0CF7CE8E38E04EC" modified="2016-01-20" version="1">MRDFLSNVPASEVPAPVRHNLNRILSAALQAVSPEECTASALTIEGQNLRAGSSTFEIRHIRSVRLLAIGKAAQRMAAGAAIVLRCLPVPLTGLVISKHIDPAIQLPKDVEVLSGGHPVPDQSSLQAGRRASEFAQASQEGDLLLCLISGGGSALVSLPVTGVTLGDLQELTRQLLACGAEIQEINALRKHLDQVKGGGIARLAQPARVVSLILSDVIGNPLDVIASGPTVPDPSSFSTCQSILEKYDLVDAIPAAIRLHLQKGLRGEIVDTPFEGDPLFANVSNWVVGSNYNAAQAALAEARQLGFQSLLLTTYLRGEASQAGLTLASLLRQIHASREPLPRPCCLVCGGETTVTLGREYGKGGRNLELALGAVQELANLPRVALISLATDGEDGPTDAAGAVVTGGTLQAGLRAKPSINAALSSHNAYPYFEQTGGLIRIGSTGTNVNDLTFLFAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XVT2</accession>
    <name>A0A0P6XVT2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4365 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_02595</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000012">
        <property type="protein sequence ID" value="KPL79424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061401.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000012.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02595"/>
    <dbReference type="EnsemblBacteria" id="KPL79424">
        <property type="protein sequence ID" value="KPL79424"/>
        <property type="gene ID" value="ADN00_02595"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025375">
        <property type="entry name" value="DUF4365"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14280">
        <property type="entry name" value="DUF4365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4365" evidence="1">
        <location>
            <begin position="17"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="468" mass="54484" checksum="DD0CCA8D787B81E7" modified="2016-01-20" version="1">MPKIVPASKFQELKGLDRISQVVHEMQCIWREISKDDIGIDGEIDLLEPRPDGKGAIATGKIIKVQAKSGSSYVKQDSASGFITPVRQEDLELWTNANYPVIFIVYHPDDDKLYWKDVKEYVRATPNIFHPPIKFVFNKETDEFTSKFRDKVLQIGNVSSPRVLFQKQERLFSNLFLLQRAPKDLYNAPILTNLDYPMITSILRSRQSFTPPFCVNRGRVFTLSDLSDPGCALREFCDTSNILIENAQPWWANPDLNRSYVSMLNRLLRMHTNRCGIKYNQQFRRFYFPRMDDTSDSVKVAWVNQRTKSHATRTVAAYYHYGHDYFWRHLAADMTFKNIGNSWFLQIIPKYLFTVDGINIWDTEKVGSYTTRQKSRERNPHVLNHILFWADYLSQGKSRVQVELDYKPIMVIEKMPQTGIADFAITDDPAIYEEPPEVLQPNLFSYILNNEDDDFIEEEPEGAEDDQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XW72</accession>
    <name>A0A0P6XW72_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_02430</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000010">
        <property type="protein sequence ID" value="KPL79671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79671">
        <property type="protein sequence ID" value="KPL79671"/>
        <property type="gene ID" value="ADN00_02430"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="277" mass="31118" checksum="1BA8FC9C5B5770DE" modified="2016-01-20" version="1">MSDNNFPIGITSVFPAGTQAVYAVFPYANMSAGMDYTVEWVVNDLTVSREDNAWESQTNGMYYCSLYDDEPLPEGDYILLLYINQEVQQYAKFTVQGEAAPEPPPQPGIPDRPATPEEVVDAQALPYFYEIFNADLPVLHEIVAINLQYWTEVIVTDDNPCGEDAIACFYKENCDVREGGKVYMTSSAMNDPSAEVTATLVHELTHGMQFYLGMPCGCTVEKEYYAMISEVDYLLYSGNEDYAYDHYGRAWDDSGAVRPDIIWDVVKAAYGDHCPDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y1L7</accession>
    <name>A0A0P6Y1L7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_03365</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061551.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78950">
        <property type="protein sequence ID" value="KPL78950"/>
        <property type="gene ID" value="ADN00_03365"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="376" mass="43262" checksum="3A0014B8E5CE13BD" modified="2016-01-20" version="1">MNINIIKNQTNAVVTEIYGKLRQGSFTKDRIKELEETLSTKIYESEKMITQCKKNNHQAAQEEFYRRRTLLKRLADGLAWILLDYDFHKIFGCSIGHSAGFMYGKEGYLTERRFINDAFNNPNVVSAIQCDITNILHLADILVFTRDKGIQPIEIKGCTSKHDRRSIRQRNRHNEIVQLINMGKSEAVLVKNTPFRSVETNMVYTHYWDVLENLSIDALKCGFSWQLLDKCVYLAVCNSRSRISSEDFLSSISDADWENGSIIISSLSRHLNKNLNNIPPYCLPITVFPITPDIGIEFLLGNLDAVIAINLEKFAEQFNKNGSYVLLKPHNELEVRIDRDQFTILEGAWSRILNELVTIPSFINQIFTVYQKSKII</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y1S7</accession>
    <name>A0A0P6Y1S7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N_BRCA1_IG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_03485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03485"/>
    <dbReference type="EnsemblBacteria" id="KPL78968">
        <property type="protein sequence ID" value="KPL78968"/>
        <property type="gene ID" value="ADN00_03485"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14947">
        <property type="entry name" value="NBR1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032350">
        <property type="entry name" value="N_BRCA1_central"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16158">
        <property type="entry name" value="N_BRCA1_IG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N_BRCA1_IG" evidence="1">
        <location>
            <begin position="87"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="187" mass="20102" checksum="A0CAA84DC572236B" modified="2016-01-20" version="1">MKKSTRPTTVSVLRFSRILLAAVVLVITSAGCSFTPTRPAPNAVNPAFIPPTFSPTQIPSPTPVPTEVMPTSSPNCVNALTYLEDITVPDGSAFAPAEKIDKQWRVENSGTCNWGKNYTLRLIAGPEMGNPVEQALYPARSGSQVIIQLNLVAPAQAGNHRSAWQAYSPQGEPFGDPIYIDIVVEEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y5N7</accession>
    <name>A0A0P6Y5N7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ANF_receptor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_09955</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062850.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76912">
        <property type="protein sequence ID" value="KPL76912"/>
        <property type="gene ID" value="ADN00_09955"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2452"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001828">
        <property type="entry name" value="ANF_lig-bd_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01094">
        <property type="entry name" value="ANF_receptor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133374" description="ANF_receptor domain-containing protein" evidence="4">
        <location>
            <begin position="30"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="domain" description="ANF_receptor" evidence="5">
        <location>
            <begin position="84"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL76912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="420" mass="44088" checksum="B83EE00C608CE53A" modified="2016-01-20" version="1">MIKHIRSWGIVLLLLTAILSACRPETAQAISVGSLWDAPAENGQIDWAAASLLAGEANRGFELASQDAAFESLRFAEGNRQDDVQAAVRQLAEGQKDTPTAGPVLALLGATSNEATARAAALANFFNLPMIVPSASGDNLLPSNNLWAFQLSAPNSTYARYLLGTVLTAQALGGGAEDESAPVARIAILYEQNTYGENAAVAAAEAAMQQNLEITVYDRFPAENANPTLLRGLANAVIDADAHIVILISSDPAAARLLAQTFKNLLDPRAMPVLVGMAGGFTSQNFLSSPEAEGVTVLRQQMQAEGCPAEIQSLYAAQNYAAVKLLAYAVEEAPNLAADREQLSLASADGISAYREAVRDALKAASLNLPCLGQVAFDNAGQNKFARIELVTAENGAARVLSAEELVAAVKQRLAPSTAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y632</accession>
    <name>A0A0P6Y632_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SBP_bac_5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_10795</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063006.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10795"/>
    <dbReference type="EnsemblBacteria" id="KPL77040">
        <property type="protein sequence ID" value="KPL77040"/>
        <property type="gene ID" value="ADN00_10795"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2636"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002741">
        <property type="entry name" value="MppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133400" description="SBP_bac_5 domain-containing protein" evidence="1">
        <location>
            <begin position="29"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="domain" description="SBP_bac_5" evidence="2">
        <location>
            <begin position="88"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="575" mass="63688" checksum="CC4913062F0652B9" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y6I6</accession>
    <name>A0A0P6Y6I6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Sialidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_00460</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00460"/>
    <dbReference type="EnsemblBacteria" id="KPL81044">
        <property type="protein sequence ID" value="KPL81044"/>
        <property type="gene ID" value="ADN00_00460"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011040">
        <property type="entry name" value="Sialidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036278">
        <property type="entry name" value="Sialidase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13088">
        <property type="entry name" value="BNR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50939">
        <property type="entry name" value="SSF50939"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="473"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="domain" description="Sialidase" evidence="2">
        <location>
            <begin position="156"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL81044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="498" mass="55622" checksum="E0C7DE64B9432F2A" modified="2016-01-20" version="1">MIIFLIAGFAAPVPCVFAEGGTDWDSPIRIPSPAYSNSWFPDVAVDRQQNVHVIWSETGDFGAGITASEALMYSVWNGSQWSQFTDIVPPQADIIRSAMTITEDDIIHVLFDSDPPFSLYYKSVPASSAYSAARWGKPMVVNGREHTYMSDIVSWGSNLHIVYDDGQFYEKECAGCADIFYRSSPDNGLTWSEPVVLLNTKLGSARAQIEVDGAGNLYVTWDEGWDRLTGLGSADHGIFMFSRDQGRTWSVPLLIEYPNNTNIQLTPAGNGKGGIMLVWRTISPNYPAIYYSWSTDWGNTWTLPQTLPNIASSQLENSFDIYDMAVDASGHIHLVATGYLASNRIESADFSNPPGLFHFEWDGENWSLPKVIFQSSWYPLYPKISISHGNQLYVVWHMRESIHSQMGYHQLWFAHGRSSAEYIEANISETTSPQTEAVMINTPTAEQPQETPTILPISSEPMRGNPFSEIDEYLILLVGIIPAAILIWIVMSRKSKNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y6P2</accession>
    <name>A0A0P6Y6P2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Quaternary ammonium transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_08895</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062645.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08895"/>
    <dbReference type="EnsemblBacteria" id="KPL77251">
        <property type="protein sequence ID" value="KPL77251"/>
        <property type="gene ID" value="ADN00_08895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007210">
        <property type="entry name" value="ABC_Gly_betaine_transp_sub-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04069">
        <property type="entry name" value="OpuAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133395" evidence="2">
        <location>
            <begin position="28"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="OpuAC" evidence="3">
        <location>
            <begin position="38"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL77251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="308" mass="33636" checksum="AEE720F505C63E74" modified="2016-01-20" version="1">MLKSKKMHKLFFVLLAAVMLVSACAPAAGSQPAESAGKVIIGSKDFTEQYIIAEMYAQILENAGFTVERKLNLGGTPIAHQAIINNEIQLYPEYTSTGLMTVLKLSPIQNAQQIFTTVKEGYEENYGLTWLEPSPFNNSQALAMTREVAAKYGITTYSDLSKVAPELILGGPPEFSEREDGIKGLQGAYGGFEFKELKQLGKGSLRYEALMAGQVDVVVAFGTDGAINGNDLLLLVDDKVFYPIYNVAPVIRQDTLTAYPQIADLLNELSPLLTDEIMSGLNWQVDGPEKKEPADVARDFLVENGLID</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y843</accession>
    <name>A0A0P6Y843_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_08040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062473.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77827">
        <property type="protein sequence ID" value="KPL77827"/>
        <property type="gene ID" value="ADN00_08040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133414" evidence="1">
        <location>
            <begin position="27"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="352" mass="38120" checksum="E45BA1DAF7E901F1" modified="2016-01-20" version="1">MTRKVVYLALALALLLAAFPATTVDAARGEPGNPEFGYGITLSAAGPMANNANFSTFQNYAQQLKPDWVAIDFDWSAIQPEARHPLALDSMDALMNLAAENQLPVLLRLVNAPPWAQTAYGPEPQLTEALLRELCDRYPGVLQAIEVFPGANTLAGWGALPDPAAYTRLFSSLSQSISQSTQGKVFLVAAGLQITDPANRHGLDIDALDFLTGLYQSGIQASMPVLSLQYQSTAGDPLDPVQSGQTTLRYYEEVRRIMLAHDHSSGLLWITRLATPISTADPIAWIENACKLLRSQLYMGAVFIDIPSTAASQAGSNGALIYNLSHADKLIQVLRQLIFQNAPEEWLTTAVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y874</accession>
    <name>A0A0P6Y874_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">DNA processing protein DprA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_08265</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DprA/Smf family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062513.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08265"/>
    <dbReference type="EnsemblBacteria" id="KPL77863">
        <property type="protein sequence ID" value="KPL77863"/>
        <property type="gene ID" value="ADN00_08265"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.655"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009294">
        <property type="term" value="P:DNA-mediated transformation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003488">
        <property type="entry name" value="DprA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041614">
        <property type="entry name" value="DprA_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43022">
        <property type="entry name" value="PTHR43022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02481">
        <property type="entry name" value="DNA_processg_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17782">
        <property type="entry name" value="DprA_WH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00732">
        <property type="entry name" value="dprA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DprA_WH" evidence="2">
        <location>
            <begin position="302"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="372" mass="40877" checksum="521344AF09B141F5" modified="2016-01-20" version="1">MDEKAYWIGFNLVKGVGAVRLQGLLDFFGNLEMAWNAPYDALRQAGLSEKIVEQFLILRKQVDLSRIMERIDQAGIRVFTWSDEDYPRRLREIDQSPPVLYCKGTIEPEDEWAVAVVGTRRISAYGRQVTQELSAFLARRGVTVVSGLARGVDALAHQTAIQNGGRTFAVLGSGVDKIYPPEHRKLAQEISERGAVISDYAPGTPPDGSNFPPRNRIISGLTLATVVIEAGETSGALITANFAANQGRDVFAVPGSIYAPQSIGANRLIQDGARPLLKMDDVLESLNLQNIFEKQTARRVLPGDEVEARLLKCLSREPLHIDEISANSGLSIDKVSATLVMMELKGMVQQVGGMNYVSIQEPNEDYRTVNHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y8Z9</accession>
    <name>A0A0P6Y8Z9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MFS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_06980</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062264.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78220">
        <property type="protein sequence ID" value="KPL78220"/>
        <property type="gene ID" value="ADN00_06980"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004752">
        <property type="entry name" value="AmpG_permease/AT-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12778">
        <property type="entry name" value="PTHR12778"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="32"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="103"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="140"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="208"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="246"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="279"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="304"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="336"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="367"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="6"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL78220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="406" mass="43987" checksum="9F6772EF1F104F4C" modified="2016-01-20" version="1">MNRSKTARYAMFGMLYFAQGAILSYFTALNSLYLLSFNISMSQIGLMGTIAMIPFVIKIFLGMLSDKVNFFHLGYRRPYIIIGLLVQSLCLFIVPFINPATHFGLFALTAFILMTGMALYDTCTDGLALDTTPKEEEGAIQGFMVGGRALGVVIISAIIGIVAERSSWTTAFNSLAVLTLLPLPLVLMARETERSAERKFEWKAFSAFTHPSVISLALLGALYSLITNAANQIVNPFLQAEFDISLSSAGFFTTIWGVGVILGSLTGGRLIDRIGQRRAVHWAIGISIGSIALLALIFNPTMAWPLVAAFGLAFGYYETVYFAISMNKSDPRIAASMFSILMAIANIGTGIGLSLSGSLVDALNYRWTFFIIAGLNLLALPLLGLIFKPGEDRSASESPSPAHTTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y9I1</accession>
    <name>A0A0P6Y9I1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Abhydrolase_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_06825</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000018">
        <property type="protein sequence ID" value="KPL78430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06825"/>
    <dbReference type="EnsemblBacteria" id="KPL78430">
        <property type="protein sequence ID" value="KPL78430"/>
        <property type="gene ID" value="ADN00_06825"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013094">
        <property type="entry name" value="AB_hydrolase_3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07859">
        <property type="entry name" value="Abhydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Abhydrolase_3" evidence="1">
        <location>
            <begin position="72"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="295" mass="33289" checksum="0D7BBC882C278ACA" modified="2016-01-20" version="1">MESVVFFMNLITLIRWQLAEYLRLPGIVYRGLRITFAPARSYECKVQYGPQARQYVYYIAPYPNTPARREIIFFAHGGGWKSYNAMIFRFVGRFFAARGYHALLAGYRPSPRFIHPAQLDDMYACLITGEQILESRGVDYSRIVLGGQSAGAQLTALMAYDQDDACRRGLDLSRIVGLFLLSGPLDFAECTTRRIGRLVRDYANTPTLYQEANPSFHVKGTERYPVLCIHGKHDPLVPLSNSVSFVSRLNGKGQLRVIDNGHHADLAAVFIDKDDPATPILTEWLDRIAAEHPTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YCB8</accession>
    <name>A0A0P6YCB8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ArsR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_02325</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000010">
        <property type="protein sequence ID" value="KPL79655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061349.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000010.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79655">
        <property type="protein sequence ID" value="KPL79655"/>
        <property type="gene ID" value="ADN00_02325"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01022">
        <property type="entry name" value="HTH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="9"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="117" mass="12909" checksum="3FCC1EE346E6CC5A" modified="2016-01-20" version="1">MQLEPLPHTLNADEERLVAMLKALGNPVRFRIMKYLAENPVCITGDIVAFAALAQSTVSQHLKVLREAGLIDGEIEGPATCYCISPEGMKFLKDRVSRWLPSCCAESRSLAKDENCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GKM8</accession>
    <name>A0A0N8GKM8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_19075</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064631.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70138">
        <property type="protein sequence ID" value="KPL70138"/>
        <property type="gene ID" value="ADN00_19075"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="75" mass="8254" checksum="7034C3215837A0D8" modified="2016-01-20" version="1">MADSKFPQSERSHDKFPKTRTFPEGWDMSGMEASSNGKSAMASDAGHCANEQDAQAPRSPEKFPKTTTMPSGWIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GLC3</accession>
    <name>A0A0N8GLC3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glyco_trans_4-like_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_16650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064167.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72098">
        <property type="protein sequence ID" value="KPL72098"/>
        <property type="gene ID" value="ADN00_16650"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3773"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="1">
        <location>
            <begin position="20"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="386" mass="42470" checksum="A6C302B51F6CA08A" modified="2016-01-20" version="1">MATLKAAQQIVHIITDLKPGGAETMLARLLAVLKSGDIRFHVISLTGDGKIGEMLRAEGIPVSVLGFDPQSPNPLLFFTLVKLLRQLKPDGIHTWLYHADLLGGLAARLAGNIPVVWALHNSTLDSTSSKRRTLRVVRLCAWLSHFVPQKITYCSTVSRDLHIQLGYKAEKMVFIPNGFDLDVFQPNADARLSVRAELGLSPETPLVGFMARFDPQKDLNNFIQAAALLNQRMPEVRFLLAGMGIQNENAVLAQWLDQSKMQGMIYLLGRRDDTPRLTAALDLATVSSAYGEAFPLVIGEAMSCEVPCVATDVGDSKMIIGTTGRVVPPRDPQALADAWYAMLSLPASERRALGYQARQIIADHYSISVSAERHQNLYRDAFNLVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GLE8</accession>
    <name>A0A0N8GLE8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_15495</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15495"/>
    <dbReference type="EnsemblBacteria" id="KPL72298">
        <property type="protein sequence ID" value="KPL72298"/>
        <property type="gene ID" value="ADN00_15495"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13581">
        <property type="entry name" value="HATPase_c_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="21"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="83"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL72298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="321" mass="35905" checksum="0F00D89F47CEE079" modified="2016-01-20" version="1">MAESITKVEELAYELRVSEVMTRDTKAISPQLPMRDVVELFRLERISGAPVVDGEQICGVVSMEDIIRCLLANDIDAPASKYMTPNPITVKLNDPVVEALKHFVTTSVGRLIVVDPQNHLQGIITKGDITRGYLRALQRQNEEEELRRYRARHLFEDIESDRTSLILRYNILAGDFRHGGAASSNIKRALLRLGATPQIARRVGIAVYEAEMNLVIHTTHGGIIRVEIEPHRMDIRVFDDGPGIEDVQKALTPGYSTATEQIRELGFGAGMGLTNIQRCVDEMTLESSPGNGTRLKMKINLDQDTMQEKKENLQNESAEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMX4</accession>
    <name>A0A0N8GMX4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_11070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063075.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76506">
        <property type="protein sequence ID" value="KPL76506"/>
        <property type="gene ID" value="ADN00_11070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.910"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007153">
        <property type="entry name" value="Adenosine_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036902">
        <property type="entry name" value="Ta1353-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36155">
        <property type="entry name" value="PTHR36155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04008">
        <property type="entry name" value="Adenosine_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103165">
        <property type="entry name" value="SSF103165"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="162" mass="17497" checksum="45BA7ED9508A2890" modified="2016-01-20" version="1">MQLETVLIEKPEETNFILGQSHFIKTVEDLHEALVSSVPGIRFGLAFCEASTKCLVRWSGNDEALIALAQKNAAAIGAGHSFIIFLGDGFYPINVLNAIKMVPEVCGIFCATANATRVLVAEEGGGRGILGVIDGNKPTGIETEEDIAWRKNFLRMIGYKAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNC1</accession>
    <name>A0A0N8GNC1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PadR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_08850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000022">
        <property type="protein sequence ID" value="KPL77682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77682">
        <property type="protein sequence ID" value="KPL77682"/>
        <property type="gene ID" value="ADN00_08850"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005149">
        <property type="entry name" value="Tscrpt_reg_PadR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03551">
        <property type="entry name" value="PadR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PadR" evidence="1">
        <location>
            <begin position="10"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="191" mass="21656" checksum="613D670949001B84" modified="2016-01-20" version="1">MDLTNAEMALLSLLAENPLHGYQIESLIEARGMRNWAEIGFSSIYYALNKMEKSGLVESRIQPEEGRPARRVYSLTEVGWQALTSAEYQRLSQPRPYSADFSLALACLPLLPVEKQIEALSERVRSLQTQEQAIQEKWQQDQPGMPAHVNHLFAYSLAQLHAERDWAQGFLNQLQSTSAAQAEEHSQETLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNK4</accession>
    <name>A0A0N8GNK4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">GDP-mannose 4,6-dehydratase</fullName>
            <ecNumber evidence="3 4">4.2.1.47</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">GDP-D-mannose dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">gmd</name>
        <name evidence="6" type="ORF">ADN00_06995</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the conversion of GDP-D-mannose to GDP-4-dehydro-6-deoxy-D-mannose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>GDP-alpha-D-mannose = GDP-4-dehydro-alpha-D-rhamnose + H2O</text>
            <dbReference type="Rhea" id="RHEA:23820"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57527"/>
            <dbReference type="ChEBI" id="CHEBI:57964"/>
            <dbReference type="EC" id="4.2.1.47"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the NAD(P)-dependent epimerase/dehydratase family. GDP-mannose 4,6-dehydratase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.47" evidence="3 4"/>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06995"/>
    <dbReference type="EnsemblBacteria" id="KPL78346">
        <property type="protein sequence ID" value="KPL78346"/>
        <property type="gene ID" value="ADN00_06995"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3216"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008446">
        <property type="term" value="F:GDP-mannose 4,6-dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070401">
        <property type="term" value="F:NADP+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019673">
        <property type="term" value="P:GDP-mannose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00955">
        <property type="entry name" value="GDP_Man_dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006368">
        <property type="entry name" value="GDP_Man_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43715">
        <property type="entry name" value="PTHR43715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01472">
        <property type="entry name" value="gmd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="5">
        <location>
            <begin position="1"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL78346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="336" mass="38612" checksum="64E8EADA5E628324" modified="2016-01-20" version="1">MLLSKGYEVHGMIRRASTFNTGRIDHLYHDPHGNGDKVNLYLHYGDLSAPQSLTDLVYNVQPDEVYHLAAQSHVRVSFDMPEYTGDVTGLGTTRILEALRRSGSKARFYQASTSELFGSANPPQNEDTPFLPRSPYAAAKMYAYWMVRNYREAYNMFATNGILFNHESPRRGETFVTRKITRAAASILAGRQKNLYLGNLDSKRDWGYAPEYVEAMYMLMQIDQPGDFVIGTGEAHTVREFLDEAFGYINLDWHDYVHIDPRYFRPTEVDYLLADPTRANQMGWKPRVTFRGLVRIMMDADLEALGLPSPGEGKRIINEQFGDWHCWEHQIMTMDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNQ1</accession>
    <name>A0A0N8GNQ1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_05620</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78722.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061992.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05620"/>
    <dbReference type="EnsemblBacteria" id="KPL78722">
        <property type="protein sequence ID" value="KPL78722"/>
        <property type="gene ID" value="ADN00_05620"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036215">
        <property type="entry name" value="TM0957-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014582">
        <property type="entry name" value="UCP033535_lipo"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10054">
        <property type="entry name" value="DUF2291"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141318">
        <property type="entry name" value="SSF141318"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78722.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="233" mass="25761" checksum="6FF657C9C01B20AB" modified="2016-01-20" version="1">MTQKTVKIIFALVVLIFLALVGRYGFTVVKIEDEEKAVQSEAFDPVSYVDGIWSTEILPAFDEKAVELVKILDELQPNQQGTAPKEDLIKVANQYGLITVGEAHVYMVKGTGTIVNVNTDTSLGTVEVKLDGYDGPIKVLLYIGTRIPSDETSVRDAVGFINFGDFKEQTEYGKVGSEINKRILSDVLGNLDKNSLMGKKISFQGAFNIRTFNLIQIELKDIRIVPVEIELGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNT5</accession>
    <name>A0A0N8GNT5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Amino acid ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_03635</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061605.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03635"/>
    <dbReference type="EnsemblBacteria" id="KPL78994">
        <property type="protein sequence ID" value="KPL78994"/>
        <property type="gene ID" value="ADN00_03635"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="62"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="91"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="143"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="190"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="219"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="245"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="270"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL78994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="332" mass="35105" checksum="0DC4D2B1AF2094F5" modified="2016-01-20" version="1">METNLILVGLAGVLAAAGPIVFATIGETITERAGVINLSANGTILLTAMAGFAVSVQTGSLALGFLVGAVIGALVALVVAFSSITLKQSQIAVGFILALLCRDLAYFLGNPFMGLPGKRVPFLPIPVLKDIPILGKLFFEQDILVYSSFLLIVLAYVYVFKTRPGLTLQGIGERPAAAFVRGADVNRLRYLYTVIGGALIGLAGPMYSLSVKAGWKGTISGLDGIGWIALALTIFGGWNPLRAALGAYLFALLQWLGLVLQPSLPGIPSQVLQVAPFPLMILTLLLVNIGNAEWVERTLAGMPEASRRVFAKILRAMRTSPPDSLGVPFENE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNV0</accession>
    <name>A0A0N8GNV0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Protein tyrosine phosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_04435</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061747.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04435"/>
    <dbReference type="EnsemblBacteria" id="KPL79114">
        <property type="protein sequence ID" value="KPL79114"/>
        <property type="gene ID" value="ADN00_04435"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.243"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023485">
        <property type="entry name" value="Ptyr_pPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036196">
        <property type="entry name" value="Ptyr_pPase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01451">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00226">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52788">
        <property type="entry name" value="SSF52788"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LMWPc" evidence="1">
        <location>
            <begin position="5"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="143" mass="15992" checksum="49EA2CE639B4C573" modified="2016-01-20" version="1">MEDQKRVLFLCTGNSARSQMAEAILRKKGGGFFEARSAGLEPKGIHPLTVRVMEEAGYDLTGQYSKGVSEYLGKEFFHYLITVCDHADKNCPSTWPGVQTRFHWSFADPAAVEGSEEERLAAFRQARDQIEAKVSAWLAEQGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GP19</accession>
    <name>A0A0N8GP19_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_02390</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000010">
        <property type="protein sequence ID" value="KPL79666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061361.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000010.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79666">
        <property type="protein sequence ID" value="KPL79666"/>
        <property type="gene ID" value="ADN00_02390"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="120" mass="13098" checksum="2EA75CC29A0C1D54" modified="2016-01-20" version="1">MDRIRFEDYKGKKVLIEDFSQMRPGPEFLALIAAAQKMIASQPQKSVLAVLDATGASFNNEILAAMKDFTKANTPYVKAAAVTGINGLLQVALSSISKFSGRSFNAFPTREAALDWLVQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WQ91</accession>
    <name>A0A0P6WQ91_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">NADH dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_15460</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="6">Binds 1 [2Fe-2S] cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I 24 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063934.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15460"/>
    <dbReference type="EnsemblBacteria" id="KPL72219">
        <property type="protein sequence ID" value="KPL72219"/>
        <property type="gene ID" value="ADN00_15460"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03064">
        <property type="entry name" value="TRX_Fd_NuoE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1590">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002023">
        <property type="entry name" value="NuoE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042128">
        <property type="entry name" value="NuoE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041921">
        <property type="entry name" value="NuoE_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000216">
        <property type="entry name" value="NADH_DH_24kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="5 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000216-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL72219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="165" mass="18324" checksum="1C19B42097738CE1" modified="2016-01-20" version="1">MSIETLNEQTVREVVKEVVHQFEANPSELIPILSEVNRRLGYLPQQAMEEVSKLVKTPKSNVLSVSTFYHMLSTKPRGRHVIQFCESAPCHVVGGREVWLALKAHLQLEAGETTPDNEWTLVTTSCLGLCGIGPVVVIDDDVYGNVTPNQLPEILSRYQAKAGEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WRA4</accession>
    <name>A0A0P6WRA4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chemotaxis protein CheA</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">ADN00_17275</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064299.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17275"/>
    <dbReference type="EnsemblBacteria" id="KPL71438">
        <property type="protein sequence ID" value="KPL71438"/>
        <property type="gene ID" value="ADN00_17275"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.518"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00088">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004105">
        <property type="entry name" value="CheA-like_dim"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037006">
        <property type="entry name" value="CheA-like_homodim_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037052">
        <property type="entry name" value="CheA-like_P2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010808">
        <property type="entry name" value="CheA_P2-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036061">
        <property type="entry name" value="CheW-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002545">
        <property type="entry name" value="CheW-lke_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035891">
        <property type="entry name" value="CheY-binding_CheA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037257">
        <property type="entry name" value="T2SS_E_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01584">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02895">
        <property type="entry name" value="H-kinase_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01627">
        <property type="entry name" value="Hpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07194">
        <property type="entry name" value="P2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00260">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01231">
        <property type="entry name" value="H-kinase_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00073">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160246">
        <property type="entry name" value="SSF160246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="SSF47226"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50341">
        <property type="entry name" value="SSF50341"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55052">
        <property type="entry name" value="SSF55052"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50851">
        <property type="entry name" value="CHEW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50894">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0902">Two-component regulatory system</keyword>
    <feature type="domain" description="HPt" evidence="12">
        <location>
            <begin position="4"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="10">
        <location>
            <begin position="367"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="domain" description="CheW-like" evidence="11">
        <location>
            <begin position="610"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="249"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine" evidence="8">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021495"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KPL71438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="745" mass="81637" checksum="31C2D7F6FBA450FE" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WT64</accession>
    <name>A0A0P6WT64_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_18490</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064525.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18490"/>
    <dbReference type="EnsemblBacteria" id="KPL70047">
        <property type="protein sequence ID" value="KPL70047"/>
        <property type="gene ID" value="ADN00_18490"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3006"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013694">
        <property type="entry name" value="VIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08487">
        <property type="entry name" value="VIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00609">
        <property type="entry name" value="VIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51468">
        <property type="entry name" value="VIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132620" evidence="3">
        <location>
            <begin position="25"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="779"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="domain" description="VIT" evidence="5">
        <location>
            <begin position="36"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="4">
        <location>
            <begin position="287"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="730"/>
            <end position="757"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51468"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL70047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="800" mass="87912" checksum="4F1615310BFE834B" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WTJ1</accession>
    <name>A0A0P6WTJ1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_18845</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064587.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18845"/>
    <dbReference type="EnsemblBacteria" id="KPL70102">
        <property type="protein sequence ID" value="KPL70102"/>
        <property type="gene ID" value="ADN00_18845"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007936">
        <property type="entry name" value="VirE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05272">
        <property type="entry name" value="VirE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="496" mass="56347" checksum="4208AF33A02BAE18" modified="2016-01-20" version="1">MTTSTTMNLFKTLLNAGVAPTDAEELEKHFEGEPDFLDGLEQIAQIMALKELPGLVPPTGEPWRSIHENMSQDMANGEDADTAWRNAIAKFDPAVAIAITGALNLRMKVILDFEQQKGKKKRVKTIEYVKVLQHQLGYDFKLNECTDNIEVNGSPIHDHLAAQIRSQMRDLGFERSQVVEDAYVSLAFQQRYHPVRQYLTSLNYDGGNYIAELASFFKDKYGMFPIWLRKWMIGACAKVFEAEQNPMLVLDGRQGIGKSEFVKWLAKPLQDYFIEAPINTEDKDSDIRLFSYWIWEVSELGATTRRADYEALKAFLTKRKVTVRKPYGHYDINKPAMASFIGTVNNSSGILNDPTGSRRFHISHLEGINWDYTSIEPDLVWAEAMAAYLARESWQLTKDEEKRAQEINEEYEITDPVEDLIRKHFKIQVGNQTWWMPTADILSILEDPFAGGLKGNTRSNAMALAGAMKKIGLEKKKQRNSNGQPVWGYVGIAYGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WV13</accession>
    <name>A0A0P6WV13_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_13940</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063639.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000033.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74102">
        <property type="protein sequence ID" value="KPL74102"/>
        <property type="gene ID" value="ADN00_13940"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL74102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="68" mass="7138" checksum="DD5DFF0CD875250C" modified="2016-01-20" version="1">MTVKEQLLRVLRSRKFWALLAALLTAAGGFASGEMSVWQAVQAAIAALAVYSTGVALEDSLKGAERGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WX30</accession>
    <name>A0A0P6WX30_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8 10">FAD:protein FMN transferase</fullName>
            <ecNumber evidence="2 8 10">2.7.1.180</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Flavin transferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">ADN00_13420</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Flavin transferase that catalyzes the transfer of the FMN moiety of FAD and its covalent binding to the hydroxyl group of a threonine residue in a target flavoprotein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8 10">
            <text>FAD + L-threonyl-[protein] = AMP + FMN-L-threonyl-[protein] + H(+)</text>
            <dbReference type="Rhea" id="RHEA:36847"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11061"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:74257"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.1.180"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="9">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="9">Magnesium. Can also use manganese.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8 10">Belongs to the ApbE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.180" evidence="2 8 10"/>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063532.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000031.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13420"/>
    <dbReference type="EnsemblBacteria" id="KPL74833">
        <property type="protein sequence ID" value="KPL74833"/>
        <property type="gene ID" value="ADN00_13420"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017013">
        <property type="term" value="P:protein flavinylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024932">
        <property type="entry name" value="ApbE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003374">
        <property type="entry name" value="ApbE-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30040">
        <property type="entry name" value="PTHR30040"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02424">
        <property type="entry name" value="ApbE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006268">
        <property type="entry name" value="ApbE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143631">
        <property type="entry name" value="SSF143631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0274">FAD</keyword>
    <keyword evidence="4 8 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7 8 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 8 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 10" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="266"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR006268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR006268-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL74833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="323" mass="34726" checksum="D49704A05DCDD64D" modified="2016-01-20" version="1">MLIGKIQGAQTTHSAMGTVMTHKVFGTHQAAALPAIVQEIGRIEALLSRFIPTSEISTINARAGMESVPVSFETFEVLSKSLELSRACPGCFAVTIRPLVALWKIGAARFSVPDTRSIQQALSLANDQDLALDQLNMTAGLRRTGQSIDLGGVGKGYAADRVAEILRDFEITSAFSNLGGNVMTLGAKPDGSPWRVGIQHPRNKDLLIGSVSAANQSVVTSGDYQRYAANRQGERFHHILNPTTGYPSQSGLVSVTIISESSQTADILSTMLFVAGIEKGLECLKKFPETEAILIDQHIRVCVTSGLKYRFQPAEGVDVSFVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZL1</accession>
    <name>A0A0P6WZL1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_15770</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063991.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72272">
        <property type="protein sequence ID" value="KPL72272"/>
        <property type="gene ID" value="ADN00_15770"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="436" mass="50010" checksum="569A0F8F2A67EEE0" modified="2016-01-20" version="1">MFIGAINSDVRKFLASLTPVLKDKKIIVGCSGNFTSEAVLTQVVQPKGIFSNDVSLYSGCAGAYLTDQEFRLQIKDEGFEWLAPYLKSTADKLSVVMILLDMLQFEKLDNIHRKRMWQNYLANFDTLFEKTNARISVARIKIDGYYAGDVYDHFCQNDHSDSVFMCYAPTYAGGYERMYKRLGQIFEWDEPSYTMLDDAARDRLLDWMRKRQYVWYDDRIIPGLDPIMVQKSGRARAVYIYSNITEKPVYLRDKLLTGLPKLRLANLHTEITANSTVKLVPIKTSDLARFKNAFLGKNILFGQGTWAFAVMVDDQTVGFIEFAKEKFGHSGLYINSDFAIPGTRYKRLSKLVVSLAVSGETRKMMERINMLRLKSLSTTAFTERPVSMKYRGVLNLVKRGVAPDGKHYLNYEGEFNQLTWKEVLHEWLTKHGSTTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X0L1</accession>
    <name>A0A0P6X0L1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ATP synthase subunit beta</fullName>
            <ecNumber evidence="10">7.1.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">ATP synthase F1 sector subunit beta</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">F-ATPase subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">atpD</name>
        <name evidence="12" type="ORF">ADN00_13865</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Produces ATP from ADP in the presence of a proton gradient across the membrane. The catalytic sites are hosted primarily by the beta subunits.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + 4 H(+)(in) + H2O = ADP + 5 H(+)(out) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:57720"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.1.2.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the ATPase alpha/beta chains family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.1.2.2" evidence="10"/>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063618.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000032.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13865"/>
    <dbReference type="EnsemblBacteria" id="KPL74373">
        <property type="protein sequence ID" value="KPL74373"/>
        <property type="gene ID" value="ADN00_13865"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1350"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1140.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01347">
        <property type="entry name" value="ATP_synth_beta_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005722">
        <property type="entry name" value="ATP_synth_F1_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020003">
        <property type="entry name" value="ATPase_a/bsu_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036121">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024034">
        <property type="entry name" value="ATPase_F1/V1_b/a_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50615">
        <property type="entry name" value="SSF50615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01039">
        <property type="entry name" value="atpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00152">
        <property type="entry name" value="ATPASE_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="4 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 10" id="KW-0139">CF(1)</keyword>
    <keyword evidence="10" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="12" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 10" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AAA" evidence="11">
        <location>
            <begin position="149"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="157"/>
            <end position="164"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KPL74373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="473" mass="52377" checksum="315BDBF2336226A7" modified="2016-01-20" version="1">MEELMEDIFGQVIQVQGSVVDVEFPAENLPDIYEAIKIDMSESYSLVVEVQRHLPGHMARCVAMGPTDGLARGTRARRTFNPIMVPVGPETLGRVFNVLGEPVDKKGDVVTAVKYPIHFRAPRLDEQVTRVEVFETGLKAIDLIAPFTKGGKTGIFGGAGVGKTVVIMELIRSIAKVHQGKSVFAGVGERTREGTQLYREMLESGVLKDTVMVYGQMNEASGARLRVALTALSMAEYFRNKGMDVLLFIDNIFRFTMSGAEVSALLGRMPSAVGYQPTLATEMGELQERITTTRHGSITSMQAVYVPADDYSDPAPVTTFTHLDATIALERSIAEKFIYPAVDPLASTSRILDANVVGWDHYNTAREVQQVLQRYKDLQDIIAILGIDELSEDDKLLVSRARKIERFFSQPMFVAEVFTGIPGQYVPLRETIRGFREILEGKHDQLPEQAFHMVGTIEQAVEKGTRMIMGQLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X224</accession>
    <name>A0A0P6X224_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Spermidine/putrescine import ATP-binding protein PotA</fullName>
            <ecNumber evidence="8">7.6.2.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">potA</name>
        <name evidence="10" type="ORF">ADN00_11430</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Part of the ABC transporter complex PotABCD involved in spermidine/putrescine import. Responsible for energy coupling to the transport system.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">The complex is composed of two ATP-binding proteins (PotA), two transmembrane proteins (PotB and PotC) and a solute-binding protein (PotD).</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the ABC transporter superfamily. Spermidine/putrescine importer (TC 3.A.1.11.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.11" evidence="8"/>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063145.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11430"/>
    <dbReference type="EnsemblBacteria" id="KPL76561">
        <property type="protein sequence ID" value="KPL76561"/>
        <property type="gene ID" value="ADN00_11430"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.986"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015594">
        <property type="term" value="F:ABC-type putrescine transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03300">
        <property type="entry name" value="ABC_PotA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017879">
        <property type="entry name" value="PotA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005893">
        <property type="entry name" value="Sp_pt_ABC_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013611">
        <property type="entry name" value="Transp-assoc_OB_typ2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08402">
        <property type="entry name" value="TOBE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01187">
        <property type="entry name" value="potA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-1278">Translocase</keyword>
    <keyword evidence="1 8" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="6"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="45"/>
            <end position="52"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU364083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL76561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="372" mass="40990" checksum="B7C1D249A99CB1D7" modified="2016-01-20" version="1">MNEIAVELRNVSKVFPADTKADEDLAAIQNVSLQIRHGEFFTLLGPSGCGKTTTLRIIAGFETPTSGDVFIKGKQMNDCPPHHRPVNTVFQNYALFPHLNVAQNIAFGLEMKHTSKAEIAERTQRVLKLVQLPDLGARKPNQLSGGQQQRVALARALVNEPAVLLLDEPLGALDLKLRKEMQIELKHLQTKLNITFIYVTHDQEEALTMSDRIAVMNNGQVLQVDSPINIYERPTSRFVAEFIGKTNFLSGRVLAGSSRETSMVLAGETVDVPLQESQWMGGDSVTLAVRPEKLQLHHDVPAPNGYRKIALHGQVREAVYAGTDTHYVVVLQSGEEVTVHMRNTFNHNLGEFAPGEAVVVTCPTEALRPLAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X3I3</accession>
    <name>A0A0P6X3I3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_13805</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063608.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000032.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13805"/>
    <dbReference type="EnsemblBacteria" id="KPL74363">
        <property type="protein sequence ID" value="KPL74363"/>
        <property type="gene ID" value="ADN00_13805"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007546">
        <property type="entry name" value="DUF503"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036746">
        <property type="entry name" value="TT1725-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36441">
        <property type="entry name" value="PTHR36441"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04456">
        <property type="entry name" value="DUF503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103007">
        <property type="entry name" value="SSF103007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL74363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="94" mass="11080" checksum="49F96467E7CD7AEE" modified="2016-01-20" version="1">MPVGLLSLQIHLADCHSLKEKRARIQPILHRLHREFNVSTSELDYNDIWKDALLGIACVSNDSIFIRQVFQEIQHFFQRAWPDVEIVDERIEIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5H7</accession>
    <name>A0A0P6X5H7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_07585</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062376.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07585"/>
    <dbReference type="EnsemblBacteria" id="KPL78308">
        <property type="protein sequence ID" value="KPL78308"/>
        <property type="gene ID" value="ADN00_07585"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="122"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="151"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="177"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="207"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="264"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="311"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="346"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="390"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL78308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="423" mass="45350" checksum="EE499F0E4FDB1C33" modified="2016-01-20" version="1">MTANTNSYHRHLEIESPTRQRVMGVIFLLVAFSIYFFFARTTAAETFTTFGLNRGATAIQVPDWELPTQSTLTILAVLSAVLGGVQLARGFKRYTNWVLAVVVAFFVFGFLTWAAADKSLNLVGLFATTLGKAVPITLGALAGILCERSGIVNIAIEGMMLSGAMVGALVGSVTKNLWLGLLAAIAVGALMAWILGVLSIKYKTNQVISGTVINILATGLTSYISAKFLQTYQELNNPGIFKPFQIPLLSKIPVLGPILFDNNLFVYLLFVLLVVLQVALFSTRWGLRLRSVGEHPKAADTLGINVNRTRYMGVILGGMVAGFAGGYFTLGSVGRFDEVMTAGRGFIGLAAMIFGNYMPFGSFGAGLLFGFADSLASRLAILQVQIPSQFLLMAPYVVTMIVLAGVVGRSQAPAAEGVPYEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X6C0</accession>
    <name>A0A0P6X6C0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_06635</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000017">
        <property type="protein sequence ID" value="KPL78591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062193.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000017.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06635"/>
    <dbReference type="EnsemblBacteria" id="KPL78591">
        <property type="protein sequence ID" value="KPL78591"/>
        <property type="gene ID" value="ADN00_06635"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016300">
        <property type="term" value="F:tRNA (uracil) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002098">
        <property type="term" value="P:tRNA wobble uridine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032873">
        <property type="entry name" value="Trm9"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13069:SF21">
        <property type="entry name" value="PTHR13069:SF21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="253" mass="28424" checksum="BB77E7C70D9F2171" modified="2016-01-20" version="1">MQPEVITHLIDLNRQFYQTFGAAFAATRRRIQPGIRQVLGRIPPAGRWLDLGCGSGSLAVEWARAGRSGAYLGLDFSRALLEEAQASVQTGAPHHPGLEISFQLTDLTQPDWDASLGSQTFDGALSFAVFHHLPSMRLRLQALSALRRRLPAGALFYHSQWQFQNSPRLMERVQPWELVGLSDADVEPNDYLLDWRYALPGQPEQVGYRYVHLFTREELAALASQAGFEVVNEFDSDGREGNLALYQTWRALD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X6H8</accession>
    <name>A0A0P6X6H8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061934.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78673">
        <property type="protein sequence ID" value="KPL78673"/>
        <property type="gene ID" value="ADN00_05310"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="76" mass="8437" checksum="BE3F70E7083D8FFE" modified="2016-01-20" version="1">MFFNSSARSGLFWALIPDAGGFYGIFFGVFIPFLFCIPKLLLTLTSEGQISQSILRFDISAGWLKGLYGSIARLNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X742</accession>
    <name>A0A0P6X742_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5 6">50S ribosomal protein L20</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplT</name>
        <name evidence="7" type="ORF">ADN00_13170</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Binds directly to 23S ribosomal RNA and is necessary for the in vitro assembly process of the 50S ribosomal subunit. It is not involved in the protein synthesizing functions of that subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the bacterial ribosomal protein bL20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000030">
        <property type="protein sequence ID" value="KPL75180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063485.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000030.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13170"/>
    <dbReference type="EnsemblBacteria" id="KPL75180">
        <property type="protein sequence ID" value="KPL75180"/>
        <property type="gene ID" value="ADN00_13170"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2885"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07026">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1900.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00382">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005813">
        <property type="entry name" value="Ribosomal_L20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035566">
        <property type="entry name" value="Ribosomal_protein_L20_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10986">
        <property type="entry name" value="PTHR10986"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00453">
        <property type="entry name" value="Ribosomal_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00062">
        <property type="entry name" value="RIBOSOMALL20"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74731">
        <property type="entry name" value="SSF74731"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01032">
        <property type="entry name" value="rplT_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00937">
        <property type="entry name" value="RIBOSOMAL_L20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL75180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="116" mass="13504" checksum="94E8CC9B9B97DB50" modified="2016-01-20" version="1">MARVKSGPYGRRRHQKILKLTKGQYGTKSKLIRRANEAMLKSLWYAYRDRRVRKRDLRKLWITRINAGARINGLSYSRLIHGLKKAEILLNRKMLADLAVRDPKAFTAVVEKARSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X751</accession>
    <name>A0A0P6X751_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">ATP synthase subunit c</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">ATP synthase F(0) sector subunit c</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">F-type ATPase subunit c</fullName>
            <shortName evidence="13">F-ATPase subunit c</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">Lipid-binding protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">atpE</name>
        <name evidence="15" type="ORF">ADN00_12425</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12 13">F(1)F(0) ATP synthase produces ATP from ADP in the presence of a proton or sodium gradient. F-type ATPases consist of two structural domains, F(1) containing the extramembraneous catalytic core and F(0) containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation.</text>
    </comment>
    <comment type="function">
        <text evidence="13">Key component of the F(0) channel; it plays a direct role in translocation across the membrane. A homomeric c-ring of between 10-14 subunits forms the central stalk rotor element with the F(1) delta and epsilon subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cell membrane</location>
            <topology evidence="13">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the ATPase C chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063335.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12425"/>
    <dbReference type="EnsemblBacteria" id="KPL76136">
        <property type="protein sequence ID" value="KPL76136"/>
        <property type="gene ID" value="ADN00_12425"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3966"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045263">
        <property type="term" value="C:proton-transporting ATP synthase complex, coupling factor F(o)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01396">
        <property type="entry name" value="ATP_synth_c_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005953">
        <property type="entry name" value="ATP_synth_csu_bac/chlpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000454">
        <property type="entry name" value="ATP_synth_F0_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020537">
        <property type="entry name" value="ATP_synth_F0_csu_DDCD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038662">
        <property type="entry name" value="ATP_synth_F0_csu_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002379">
        <property type="entry name" value="ATPase_proteolipid_c-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035921">
        <property type="entry name" value="F/V-ATP_Csub_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10031">
        <property type="entry name" value="PTHR10031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00137">
        <property type="entry name" value="ATP-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00124">
        <property type="entry name" value="ATPASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81333">
        <property type="entry name" value="SSF81333"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01260">
        <property type="entry name" value="ATP_synt_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00605">
        <property type="entry name" value="ATPASE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 13" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="13" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 13" id="KW-0138">CF(0)</keyword>
    <keyword evidence="6 13" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="8 13" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 13" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="10 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 13" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="53"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_C" evidence="14">
        <location>
            <begin position="12"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="site" description="Reversibly protonated during proton transport" evidence="13">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00025198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KPL76136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="78" mass="7675" checksum="192F6C65C76495F3" modified="2016-01-20" version="1">MTGDIVAAAKLIGAGLAMIGTIGAGAGIGILVNGAVQGMARNPDASGNVQTNMILGIAFAEAVAIYCLVVALLILFVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7C6</accession>
    <name>A0A0P6X7C6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_08105</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062484.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08105"/>
    <dbReference type="EnsemblBacteria" id="KPL77838">
        <property type="protein sequence ID" value="KPL77838"/>
        <property type="gene ID" value="ADN00_08105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="449" mass="49604" checksum="AA5CB7A54D5F2427" modified="2016-01-20" version="1">MDKDEVLATCMKHNFWTWSAQNHAHPIAVERAEGVYFWDMDGKRYLDFNSMVMCANVGHGEPRIRQAMIEQIETLTFAGPHMATLPRARICQKLLEIVPAGLEKFLFTLGGADANENAVKLARGYTGKFKILSQYRSYHGATFGALALTGDPRRTSWEPGVMPGVVHFSGPYRYRSALHASGEVISDEQLCRDYLHHLENIIRFEGPETIAGILMESVTGTNGVLIPPDGYLAGVRALCDRYHICLILDEVMAGFGRTGKWFACQHWGVTPDIMTMAKGLTGAYAPLGAVAMKAEVAAAYNEKVYQGGLTFNGHPVSLAAAIATIQMMQDDHIVDRAAQTGQVFAQELKQLMEKHPCIGEARSIGLFGAIELVKNRSSREPLADYNASSPTIKTLVNDLESAGLYIHAHWNVLLLIPPLIIRPEELREGFALIDKALTKVDHEIVKLNM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7G6</accession>
    <name>A0A0P6X7G6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">2,5-didehydrogluconate reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_08515</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062560.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08515"/>
    <dbReference type="EnsemblBacteria" id="KPL77902">
        <property type="protein sequence ID" value="KPL77902"/>
        <property type="gene ID" value="ADN00_08515"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.707"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="15"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="313" mass="35237" checksum="379269C0FB15918B" modified="2016-01-20" version="1">MEEERRRHPVFSGVELGIGTWSWGDRLIWGYGKGYQDQDIFEAFETSVAAGIIFFDTAEVYGQGKSESLLGQCMKTTDARIRVATKFMPYPWRLSKQNLLKAVRRSIKRLGLERVDLYQIHMPLPPVTVETWMDAMTAAYQEGLIGAVGVSNFDLGQTQRAKESLARNGIPLASNQVEYHLLNRKMEKNGLFQFCQENEITLIAYSPLGMGLLTGKYTPENMPQGVRAGRVRKDYLQKIQPLLLELRRIGSAHDGKTAAQVAINWCICKDSIPIPGAKNREQAKQNAASGGWRLTEEEVARLEQLSDQIEASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7J0</accession>
    <name>A0A0P6X7J0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Radical SAM core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_18990</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064615.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18990"/>
    <dbReference type="EnsemblBacteria" id="KPL70126">
        <property type="protein sequence ID" value="KPL70126"/>
        <property type="gene ID" value="ADN00_18990"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="5">
        <location>
            <begin position="158"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL70126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="386" mass="43023" checksum="432E57ECC45B1ECA" modified="2016-01-20" version="1">MNALQSFLNRFFKPVKPLPAGMYPYQTPPEAPQQYRLHLRLEENGSGILIVNASIVLHLNHTAAEYAYYLVKDMPEQVIASQMARRYNVPQDKALQDYQDFKERLDILVQTPDLDPVGFLGFDRKEPLSAAVLAPYRLDCALTYQVSDGESGSVAPLERVRRELVEHEWQQIINKAWAAGIPHVVFTGGEPTLRPDLAALLTHAEGLGMVTGLLTDGLRLTNPDYLHELLDCGLDHIMLVFQPEEEQSWEALRDLMPEDIHTTVHLTITEKNQEDVNTILQRMASMGVQSLSLSAANIQLKPALDQAAITAADLQISLVWNLPVPYSSLNPVALDQEEAGDIPDADGLSALYVEPDGDVLRGQGQPEVLGNLLRDEWSTIWQHARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7Q4</accession>
    <name>A0A0P6X7Q4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_04020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79057">
        <property type="protein sequence ID" value="KPL79057"/>
        <property type="gene ID" value="ADN00_04020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="78" mass="8823" checksum="5FCEA6B2DD61A11C" modified="2016-01-20" version="1">MFIKFIFLKTRQFMSILMVLYEDSRQSSRVVAGARLIIPRLETPACPDRGLNSKGGLCGWAAFLLSAPQTDPCWKMSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7X8</accession>
    <name>A0A0P6X7X8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_12860</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063422.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000027.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12860"/>
    <dbReference type="REBASE" id="132873">
        <property type="entry name" value="OapP3M1ORF12865P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL75527">
        <property type="protein sequence ID" value="KPL75527"/>
        <property type="gene ID" value="ADN00_12860"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140658">
        <property type="term" value="F:ATP-dependent chromatin remodeler activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024975">
        <property type="entry name" value="NOV_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13020">
        <property type="entry name" value="DUF3883"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="2">
        <location>
            <begin position="114"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="3">
        <location>
            <begin position="462"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="395"/>
            <end position="427"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL75527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="1116" mass="126932" checksum="3430176885885B31" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X848</accession>
    <name>A0A0P6X848_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Potassium transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_16695</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064188.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16695"/>
    <dbReference type="EnsemblBacteria" id="KPL71348">
        <property type="protein sequence ID" value="KPL71348"/>
        <property type="gene ID" value="ADN00_16695"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.397"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005451">
        <property type="term" value="F:monovalent cation:proton antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006153">
        <property type="entry name" value="Cation/H_exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038770">
        <property type="entry name" value="Na+/solute_symporter_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030151">
        <property type="entry name" value="NhaP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32507:SF7">
        <property type="entry name" value="PTHR32507:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00999">
        <property type="entry name" value="Na_H_Exchanger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02080">
        <property type="entry name" value="TrkA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="30"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="90"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="189"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="272"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="296"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="333"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="365"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="5">
        <location>
            <begin position="402"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL71348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="474" mass="50748" checksum="B90C1232E9740885" modified="2016-01-20" version="1">MSLEIVLIGASLLLLLSIFASKVSDRFGVPALLLFLGVGMLAGSDGIGGIYFDDARVAQAVGSVALVLILFSGGLDTDWKQVRGVLREGLTLATLGVLLTAVVTGFFVHVLLGFSMVEGLLVGAIVSSTDAAAVFSVLRSKGIHLKGNLKPLLELESGCNDPMAIFLTTGLIQLLQSPALTPLNLVGQFFIQMLVGGAVGFLMSWVALFLIRRLKLGYEGLYPVLTLALAFFVFGLTNVMGGNGYLAVYLVGVFLSRHSFIHRQSLLNFHDGMAWLMQIAMFLTLGLLVFPTRLLAVSGVALVVALCLMLLARPLGVFISLLQFGVPWRDKLFISWVGLRGAVPIILATYPMLAGLPNADLIFNVVFFVVLTSVLLQGTTLPLAARWLSVDAPAVEKRRYPIKFTPMSGLKSELKELLVPEGSAMANQQVVDLGLPAEFLIVMIARGEDFLISSGGTKILEGDVCNGPQKLDTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X895</accession>
    <name>A0A0P6X895_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">ATP-dependent 6-phosphofructokinase</fullName>
            <shortName evidence="15">ATP-PFK</shortName>
            <shortName evidence="15">Phosphofructokinase</shortName>
            <ecNumber evidence="15">2.7.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Phosphohexokinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">pfkA</name>
        <name evidence="17" type="ORF">ADN00_16980</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 15">Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6-bisphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16109"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 15">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="15">Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5 15">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 15">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.11" evidence="15"/>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064243.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16980"/>
    <dbReference type="EnsemblBacteria" id="KPL71393">
        <property type="protein sequence ID" value="KPL71393"/>
        <property type="gene ID" value="ADN00_16980"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.456"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00182"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003872">
        <property type="term" value="F:6-phosphofructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00339">
        <property type="entry name" value="Phosphofructokinase_I_B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022953">
        <property type="entry name" value="ATP_PFK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012003">
        <property type="entry name" value="ATP_PFK_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012828">
        <property type="entry name" value="PFKA_ATP_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015912">
        <property type="entry name" value="Phosphofructokinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000023">
        <property type="entry name" value="Phosphofructokinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035966">
        <property type="entry name" value="PKF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00365">
        <property type="entry name" value="PFK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000532">
        <property type="entry name" value="ATP_PFK_prok"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00476">
        <property type="entry name" value="PHFRCTKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53784">
        <property type="entry name" value="SSF53784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02482">
        <property type="entry name" value="PFKA_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00433">
        <property type="entry name" value="PHOSPHOFRUCTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 15" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="12 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 15" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="14 15" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="11 15 17" id="KW-0418">Kinase</keyword>
    <keyword evidence="13 15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 15 17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PFK" evidence="16">
        <location>
            <begin position="8"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="ADP binding; allosteric activator; shared with dimeric partner" evidence="15">
        <location>
            <begin position="25"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="15">
        <location>
            <begin position="129"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="15">
        <location>
            <begin position="173"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="region of interest" description="ADP binding; allosteric activator" evidence="15">
        <location>
            <begin position="189"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="region of interest" description="ADP binding; allosteric activator" evidence="15">
        <location>
            <begin position="217"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="15">
        <location>
            <begin position="255"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="15">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <begin position="76"/>
            <end position="77"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <begin position="106"/>
            <end position="109"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>ADP</name>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <note>allosteric activator</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>ADP</name>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <note>allosteric activator</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="226"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="249"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KPL71393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="325" mass="34442" checksum="426C68AED600ED00" modified="2016-01-20" version="1">MGQKYKSIGVLTSGGDAPGMNACIRAVVRSASAMNIKVWGVEGGFTGLIRGKYKEMGNRDVGNILQRGGTILQTARCEEFRAPAGRREALREMNNAGMEALVVIGGDGSLNGAQKLAELGVPVVGVPASIDNDIYGTDMAIGVDTALNTIVDAIDKLRDTASSHTRAFLVETMGHASGYLAIQAGIVTGAEMVLVPEVATSVEDVAARVEEAYRRGKAHCIIVVAEGFSPPTNELAEAIDKLDHGFTTRVSILGHIQRGGSPTAFDRMLASRFGMKAVEFLVDGKLNMMTALRGREIVPVPIADVVSNARPVAEEYIEMARVLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9V9</accession>
    <name>A0A0P6X9V9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_10510</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062955.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76996">
        <property type="protein sequence ID" value="KPL76996"/>
        <property type="gene ID" value="ADN00_10510"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132947" evidence="2">
        <location>
            <begin position="24"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL76996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="481" mass="51083" checksum="AE81C506E855CCE4" modified="2016-01-20" version="1">MKKKTPILLLVCCALLLISVSCASLPIPGLSPSAPNQPASGEPAGEIQPVSTNAEGGLTLATSTPKPLVLQSPTPPAPGQPEPAALDVWAYNRLDQKLIGLDARTFELKNELIMDGEPGGVAVTEQGAWVLDVSGNRILRIDPATNSVAATLLAPGFKLRAIAAGEGSVWVGVEEVPLEGAASATPLGGVLRLNPGSDEISQYIETSAPVTDFAFRPGEVWIISTSQGFNTLSQIDPATNTVSTRGDSSIWYETSHISANAYGLWLINTTAPNTVQQIDLTSGNLLSATKLDRVPGTARDIVASQDAVWVLMDNGTVARFDPQRLEVYSIIPVASFVDEIFAQSGAIYVSSQFEGKIFRVDVAQNRVSANFVTGQAMPTPTPTAAPTKPAYGACDAAYLSRLHVGDKARVKEIPPQANRVRSEPNIEAETLGYIQPGVGMTILEGPQCSNNWVWWKVEADTGLVGWTAEGDEKGYWLEVIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9W2</accession>
    <name>A0A0P6X9W2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Multifunctional fusion protein</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="6">Shikimate kinase</fullName>
                <shortName evidence="6">SK</shortName>
                <ecNumber evidence="6">2.7.1.71</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="7">3-dehydroquinate synthase</fullName>
                <shortName evidence="7">DHQS</shortName>
                <ecNumber evidence="7">4.2.3.4</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="6" type="primary">aroK</name>
        <name evidence="7" type="synonym">aroB</name>
        <name evidence="9" type="ORF">ADN00_02480</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the conversion of 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) to dehydroquinate (DHQ).</text>
    </comment>
    <comment type="function">
        <text evidence="6">Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>7-phospho-2-dehydro-3-deoxy-D-arabino-heptonate = 3-dehydroquinate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21968"/>
            <dbReference type="ChEBI" id="CHEBI:32364"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58394"/>
            <dbReference type="EC" id="4.2.3.4"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + shikimate = 3-phosphoshikimate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13121"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.71"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 divalent metal cation per subunit. Can use either Co(2+) or Zn(2+).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="7">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 2/7.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 5/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the shikimate kinase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the sugar phosphate cyclases superfamily. Dehydroquinate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.71" evidence="6"/>
    <dbReference type="EC" id="4.2.3.4" evidence="7"/>
    <dbReference type="EMBL" id="LGCL01000011">
        <property type="protein sequence ID" value="KPL79579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02480"/>
    <dbReference type="EnsemblBacteria" id="KPL79579">
        <property type="protein sequence ID" value="KPL79579"/>
        <property type="gene ID" value="ADN00_02480"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2806"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00085"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003856">
        <property type="term" value="F:3-dehydroquinate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004765">
        <property type="term" value="F:shikimate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00464">
        <property type="entry name" value="SK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00110">
        <property type="entry name" value="DHQ_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00109">
        <property type="entry name" value="Shikimate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016037">
        <property type="entry name" value="DHQ_synth_AroB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030960">
        <property type="entry name" value="DHQS/DOIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031322">
        <property type="entry name" value="Shikimate/glucono_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000623">
        <property type="entry name" value="Shikimate_kinase/TSH1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01761">
        <property type="entry name" value="DHQ_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01202">
        <property type="entry name" value="SKI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01357">
        <property type="entry name" value="aroB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3 7" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0170">Cobalt</keyword>
    <keyword evidence="2 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="DHQ_synthase" evidence="8">
        <location>
            <begin position="231"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="2"/>
            <end position="7"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="6"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="24"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="48"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="234"/>
            <end position="239"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="268"/>
            <end position="272"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="292"/>
            <end position="293"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="305"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="314"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="332"/>
            <end position="335"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="347"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="410"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="426"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL79579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="526" mass="56135" checksum="379E4640DA8358A8" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9Y3</accession>
    <name>A0A0P6X9Y3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NYN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062164.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78871">
        <property type="protein sequence ID" value="KPL78871"/>
        <property type="gene ID" value="ADN00_05460"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021139">
        <property type="entry name" value="NYN_MARF1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01936">
        <property type="entry name" value="NYN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NYN" evidence="1">
        <location>
            <begin position="8"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="275" mass="31393" checksum="BD2FE3BDFB1B7557" modified="2016-01-20" version="1">MPNSSSSKVGVYVDVVNMYRNGGQRMRYDVLREFACRDMAEPLRLNAYVSYDAERAGQDYAYKEGINSFHSALRDLGFKVIVKEIRWYQDESGNRYGKADADLDLAVDAMVQSQHLDKVLIASGDGDFVRLVQALQNRGCRVEVVGLSNVSRALREEADLYVSGFLIPNLIPIEQDQQVNWGDVGSRTRGWCYWHHASQSFGFLRFMKTINNNLWLTDTRNPLSPFGTAFFHDSELPYDRISANQLPSRNLIFEFELTESERGLQAVDIQLISRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9Y8</accession>
    <name>A0A0P6X9Y8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Sugar-bind domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_11350</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SorC transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063130.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76551">
        <property type="protein sequence ID" value="KPL76551"/>
        <property type="gene ID" value="ADN00_11350"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.969"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007324">
        <property type="entry name" value="Sugar-bd_dom_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04198">
        <property type="entry name" value="Sugar-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sugar-bind" evidence="2">
        <location>
            <begin position="59"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL76551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="319" mass="34809" checksum="46CA19F1ACC74A67" modified="2016-01-20" version="1">MDTQRIELLARIADLYYNQNLRQEEVARRTGYSRSMVSRLLTEAREEGVVEIRVNFPLDRCADLEKELRDRFHLQEARVLARGSLSYEEMLRQVGVLAARLVESMLNETIHTVGVSWGTALWETANAMRPTAYAGVQVVQVIGALDAPNAEIDGPDLARKYARLFGGHYLTLPVPLAVHNPEARDALLADARVRRTLDMAKNMDMLLAGMGSMEPEACSILRAGYLSREEVLGLTQYGVAGDVCGILFDRSGNLLATDFGLRRVGLSAEDIMRTPIKIGIGGGKPKALPLMGACQAGLINVAVTDEVAALGALRAMSQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XA14</accession>
    <name>A0A0P6XA14_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">4Fe-4S ferredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_17000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064247.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17000"/>
    <dbReference type="EnsemblBacteria" id="KPL71397">
        <property type="protein sequence ID" value="KPL71397"/>
        <property type="gene ID" value="ADN00_17000"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.460"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007160">
        <property type="entry name" value="DUF362"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04015">
        <property type="entry name" value="DUF362"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12838">
        <property type="entry name" value="Fer4_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="1">
        <location>
            <begin position="187"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="1">
        <location>
            <begin position="217"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL71397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="372" mass="40781" checksum="3116527C68D6272E" modified="2016-01-20" version="1">MTASKVYFTNMRTKPGRNMLDKLTALLKKAGMNTIHFDNKFTAVKIHFGEPGNLAYIRPNYAAVVIREIKKLGGKPFLTDANTLYHGRRANAVDHLQSAMENGFNRIAVGCDVIIADGLTGNDYIEIPIELKHCQTAKIGSAIAQADVFISMTHFKGHEMTGFGGALKNIGMGSGSVGGKMEMHSTSKPVIVEENCTSCGICIRNCAQHAISFNDNKKAAINYDLCVGCGQCVAVCQFDAARVIWDKSGDTVAEKIAEYAYAVCKDKPHFHISFVMNVSPDCDCWDLNDQAIVPDIGIFASFDPVALDRACVDMVNQAPMIYGSVLTDKDYEEGEHEDKFGHIHPDTHWKACLDHAESIGLGTQEYELVMVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAG2</accession>
    <name>A0A0P6XAG2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_04340</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061732.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04340"/>
    <dbReference type="EnsemblBacteria" id="KPL79100">
        <property type="protein sequence ID" value="KPL79100"/>
        <property type="gene ID" value="ADN00_04340"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132954" evidence="2">
        <location>
            <begin position="34"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="485" mass="53990" checksum="A781A923E3D2F628" modified="2016-01-20" version="1">MKKTTSPTPLLHRLLAATLALFFLLSACQPLTPAEQTVEAQHQTEQASQPTPTRPAAPQPTPTRPSYLDLDLESLKGLTIRFWHPWTGSLAAEANRLVDEFNRTNVWGFQVQAVPTGGSTALFNQMEQTLRAENQRPHLVAAPADQVHLWQRKFNAVVSLDAYLNDAEWGMPVEEQAAYLPLFWQQDQVSGRQIAIPALRDAHLLAFNITWAKDLGFSQPPSTPKDFQEQVCAAAQARKQTSNDGTGGWITSSDPYVLLSWLNAFGWDGLDDLQQDQAQFNTPRSQEALAYLRGLFNRGCAWNSRLPDPYEYFANRQALAYSLTLSQASLQAETLERLQSKDQWMLLPYPAQSAGSVPSFFTSGDSYAMLVASPQEQLAAWLFMRWMSNPRSQASLAQAGGLLPVTTTAAEQMTPYARQHPGWQQAYDLIAAAQPAPNAAAWPYTSLVLSDAAWQTWQGEMDEEKLNQILAQIDLTLPEIYNLVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAU7</accession>
    <name>A0A0P6XAU7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062815.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76880">
        <property type="protein sequence ID" value="KPL76880"/>
        <property type="gene ID" value="ADN00_09770"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="101" mass="10872" checksum="5B49467F4416D3A1" modified="2016-01-20" version="1">MNDVLVVVLGLVIAMGGLIAVATLLEKRSKKSGPNKLTLPEAGPTAKKYVWITRALVTLLVLSIVGVFVFRSIELAWFAGACMLIYLIAGTIARFTRLIGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XB12</accession>
    <name>A0A0P6XB12_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_03200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000014">
        <property type="protein sequence ID" value="KPL79347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79347">
        <property type="protein sequence ID" value="KPL79347"/>
        <property type="gene ID" value="ADN00_03200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="93"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="107" mass="11476" checksum="7677B6C7DCCDA19D" modified="2016-01-20" version="1">MGKPPPSTPRSSHPPARSPASPLSNPPQQPVPPTPLPSPGTPRWPRPAPPSWPPPTRGWALRRWVIPLPAARTSQPARPAYFPPAGRSRPAEPQPIPSTTIARFSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XCZ7</accession>
    <name>A0A0P6XCZ7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C</fullName>
            <shortName evidence="1">Asp/Glu-ADT subunit C</shortName>
            <ecNumber evidence="1">6.3.5.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">gatC</name>
        <name evidence="2" type="ORF">ADN00_01745</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O + L-aspartyl-tRNA(Asn) + L-glutamine = ADP + 2 H(+) + L-asparaginyl-tRNA(Asn) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14513"/>
            <dbReference type="Rhea" id="RHEA-COMP:9674"/>
            <dbReference type="Rhea" id="RHEA-COMP:9677"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78515"/>
            <dbReference type="ChEBI" id="CHEBI:78516"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln) = ADP + H(+) + L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17521"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="Rhea" id="RHEA-COMP:9684"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Heterotrimer of A, B and C subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GatC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.-" evidence="1"/>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061237.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01745"/>
    <dbReference type="EnsemblBacteria" id="KPL80590">
        <property type="protein sequence ID" value="KPL80590"/>
        <property type="gene ID" value="ADN00_01745"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050566">
        <property type="term" value="F:asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050567">
        <property type="term" value="F:glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006450">
        <property type="term" value="P:regulation of translational fidelity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00122">
        <property type="entry name" value="GatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003837">
        <property type="entry name" value="Asp/Glu-ADT_csu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036113">
        <property type="entry name" value="Asp/Glu-ADT_sf_sub_c"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15004">
        <property type="entry name" value="PTHR15004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02686">
        <property type="entry name" value="Glu-tRNAGln"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141000">
        <property type="entry name" value="SSF141000"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00135">
        <property type="entry name" value="gatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="95" mass="10495" checksum="74A68C355C810198" modified="2016-01-20" version="1">MSLTQSEVEHIAELARLDLTAEELESFRQQLSDILEYAARLQSVDTSGIPPTSSVLPPRSVLRPDVAEQGLSADDVLRNAAQTENHQFRVPPVLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDG5</accession>
    <name>A0A0P6XDG5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_01165</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000003">
        <property type="protein sequence ID" value="KPL80855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061156.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01165"/>
    <dbReference type="EnsemblBacteria" id="KPL80855">
        <property type="protein sequence ID" value="KPL80855"/>
        <property type="gene ID" value="ADN00_01165"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1978"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="22"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="87"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="178"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="271"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="305"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL80855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="337" mass="36037" checksum="7E91EAEEEAB68540" modified="2016-01-20" version="1">MAVRFYNVLTVDPFGADVWTRIAISGLILGGMYALIAIGYTLVYGILFMINFAHGEVMMIGSFGGYFAFEILKNIPMPTEADPKLTFINAQPVLSIIIAFLIGMSLASMSGYFLEKIAYRPLRGAPRLVPLISAIGASIFLQNAAQLLFGPQRRDYSNPDLLWRGSGWTVEIAGSPVIITYTGVFSFVLSILLMVGLYMLVQRTKLGRAMRAVAQDKKTAALMGINVNQIISQTFIISGALAGAAGVMWGIHNGLINHYVGFIPGIKAFTAAVLGGIGNIPGAMVGGLTLGILETLGPAALGIDFQLKDVIAFSILVLVLIFRPSGILGEALSEEKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDH5</accession>
    <name>A0A0P6XDH5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Endo/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_00185</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DNA repair enzymes AP/ExoA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060938.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00185"/>
    <dbReference type="EnsemblBacteria" id="KPL81005">
        <property type="protein sequence ID" value="KPL81005"/>
        <property type="gene ID" value="ADN00_00185"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3432"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008853">
        <property type="term" value="F:exodeoxyribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004808">
        <property type="entry name" value="AP_endonuc_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020847">
        <property type="entry name" value="AP_endonuclease_F1_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22748">
        <property type="entry name" value="PTHR22748"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00633">
        <property type="entry name" value="xth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00726">
        <property type="entry name" value="AP_NUCLEASE_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51435">
        <property type="entry name" value="AP_NUCLEASE_F1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endo/exonuclease/phosphatase" evidence="2">
        <location>
            <begin position="7"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL81005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="263" mass="30568" checksum="8358D961821A0EF6" modified="2016-01-20" version="1">MNEFQIATWNVNGIRAAIRNGFLDWLSIYSPDVVCLQEVKAFESQVEVDFSTYGYQPIWNSAQKPGYSGVLTLTKTPADEVKFGLDDERFNDEGRVIRHRFGSVYLYNIYFPNGQRGHDRVAYKLDFYASLLAECQALFDKQKSIIITWDFNTAHQEMDLANPKENQNTSGFLPEEREAVSEYLSKGFIDAYRRLHPETVKYTWWTYRFQARKRNIGWRLDYFLMNEAVFSATNDVVILDEVNGSDHCPVILHLDAEKLAQLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDI6</accession>
    <name>A0A0P6XDI6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_00300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060958.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00300"/>
    <dbReference type="EnsemblBacteria" id="KPL81023">
        <property type="protein sequence ID" value="KPL81023"/>
        <property type="gene ID" value="ADN00_00300"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL81023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="193" mass="22096" checksum="DB3008CEB5EE086F" modified="2016-01-20" version="1">MTEAAKKWNQRYSGEIQEGLKTPRQLLLDYEYLLPRRGYVLDLAMGLGANAGYLHQRGLNVVGVDISTTAALNARESFSDLPIFVADLENWRFTTTFDVILNFYYFQRNLAAQFSSMLNPGGWLLVETLHWDILEVKPDINPDYLVQPRELLDLASGFDVHHYFEGWIQNSAGRKKWVAQLVAKKRNNGGRKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDW8</accession>
    <name>A0A0P6XDW8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RanBP2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_00995</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061085.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL81129">
        <property type="protein sequence ID" value="KPL81129"/>
        <property type="gene ID" value="ADN00_00995"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1060.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025874">
        <property type="entry name" value="DZR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038587">
        <property type="entry name" value="L40e_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036443">
        <property type="entry name" value="Znf_RanBP2_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12773">
        <property type="entry name" value="DZR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00641">
        <property type="entry name" value="zf-RanBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00547">
        <property type="entry name" value="ZnF_RBZ"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90209">
        <property type="entry name" value="SSF90209"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01358">
        <property type="entry name" value="ZF_RANBP2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50199">
        <property type="entry name" value="ZF_RANBP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="156"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="RanBP2-type" evidence="5">
        <location>
            <begin position="5"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL81129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="358" mass="39172" checksum="A48587F76A0D0929" modified="2016-01-20" version="1">MAKKTVGTIDLEWICPNCNNRNPGPQKTCLSCGAAQPADVEFILPERQEISTDQQKLEAAKKGPDIHCPYCGARNPQGAEICTQCGGDLTQGVKRTSGQVIGAYSNALKKEILCPACGQPNAVDQLKCANCGAPLKPAEQIATPKPQAAPVKANPFFIGCGVILLLAMIIGMFLIFGRREDLTGRVTGAEWQRAILVEEFGPVTRQDWQDKVPVEASNLRCETRFRTSSNEYVPGAEEVCGTAYIVDSGTGQGEVVQDCVYNIYDDYCSYEINEWHSGSPVELSGRDYNPIWPNPQLSADQRLGERSASYTIFFEADGEKYTYRTSDERLFQACQPGTRWVLTVNPSLGSIISIQPAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XF00</accession>
    <name>A0A0P6XF00_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptide deformylase</fullName>
            <shortName evidence="2">PDF</shortName>
            <ecNumber evidence="2">3.5.1.88</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Polypeptide deformylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">def</name>
        <name evidence="3" type="ORF">ADN00_06945</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>H2O + N-terminal N-formyl-L-methionyl-[peptide] = formate + N-terminal L-methionyl-[peptide]</text>
            <dbReference type="Rhea" id="RHEA:24420"/>
            <dbReference type="Rhea" id="RHEA-COMP:10639"/>
            <dbReference type="Rhea" id="RHEA-COMP:10640"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:49298"/>
            <dbReference type="ChEBI" id="CHEBI:64731"/>
            <dbReference type="EC" id="3.5.1.88"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="2">Binds 1 Fe(2+) ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the polypeptide deformylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.88" evidence="2"/>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062258.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06945"/>
    <dbReference type="EnsemblBacteria" id="KPL78215">
        <property type="protein sequence ID" value="KPL78215"/>
        <property type="gene ID" value="ADN00_06945"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3205"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042586">
        <property type="term" value="F:peptide deformylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00487">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.45.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00163">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023635">
        <property type="entry name" value="Peptide_deformylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036821">
        <property type="entry name" value="Peptide_deformylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10458">
        <property type="entry name" value="PTHR10458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01327">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004749">
        <property type="entry name" value="Pep_def"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01576">
        <property type="entry name" value="PDEFORMYLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56420">
        <property type="entry name" value="SSF56420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00079">
        <property type="entry name" value="pept_deformyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="2">
        <location>
            <position position="141"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="169" mass="19137" checksum="F65E7DCBEACE7096" modified="2016-01-20" version="1">MTIREIALVPEPVLRRKARKLTDFGPETQKLIDDMVETMREAPGVGLAAPQIAESLQLVVVEFAEDEENEDAKPKLFVVVNPEIVKRSEETVMGIEGCLSIPGLVGDVERNESVEIKALNRHGKPIKIKARGWLARIFQHEIDHLDGVLYTDRATRVWQPKEEEEFEDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XF10</accession>
    <name>A0A0P6XF10_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05975</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05975"/>
    <dbReference type="EnsemblBacteria" id="KPL78779">
        <property type="protein sequence ID" value="KPL78779"/>
        <property type="gene ID" value="ADN00_05975"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACT" evidence="1">
        <location>
            <begin position="32"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="1">
        <location>
            <begin position="126"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="231" mass="25729" checksum="2D6E08580FDD9386" modified="2016-01-20" version="1">MLSLPINSPQKAFFAIIPRLEVSMSDTQEQFIISIMSRDRVGIVYEISNAVSQLNGNLADVRQTLMCGYFTMILLASFPPEVTQRTIERKLAEVDARSETPIVAAVKRLDATDLRPTADFPENSYVLTARGPDRIGFVATVSNFCQQHNINILDLSTTASDQEYLMILIIDLSQAASITQVRQDLKQFTQETGLQMVLQHRDIFRAVNEINLPARVGGNISLIQFDSHIGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XF29</accession>
    <name>A0A0P6XF29_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">CRISPR-associated protein Csd2</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_06170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062090.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06170"/>
    <dbReference type="EnsemblBacteria" id="KPL78806">
        <property type="protein sequence ID" value="KPL78806"/>
        <property type="gene ID" value="ADN00_06170"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1735"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043571">
        <property type="term" value="P:maintenance of CRISPR repeat elements"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006482">
        <property type="entry name" value="Cas7_Csh2/Csh2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013418">
        <property type="entry name" value="CRISPR-assoc_prot_Csd2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05107">
        <property type="entry name" value="Cas_Cas7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02589">
        <property type="entry name" value="cas_Csd2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01595">
        <property type="entry name" value="cas_CT1132"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="289" mass="32817" checksum="9A3051D722F2F6F3" modified="2016-01-20" version="1">MSEAIKNRYEFVLLYDVENGNPNGDPDAGNMPRIDPETGYGIVTDVCLKRKIRNFVELVKSDATGYRIYIKEGVPLNQNHVEAYEAVGLKSGDKAKPDKVNEARQWMCKNFYDIRTFGAVLMVGDNCGQVRGPVQINFSRSLDPIVQQEVTITRQTVTRIEEAEKERTMGRKHIVPYGLYRVEGYISAKLANDASKGTGFSEDDLTLFWDALINMFEHDRSAARGKMAVRKLIVFQHDSDLGNVPAHKLFDLVKVHRNPEVNPPRRFEDYEVTIHFADVPPSVKLIEKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XF36</accession>
    <name>A0A0P6XF36_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NADH dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_07210</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062307.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07210"/>
    <dbReference type="EnsemblBacteria" id="KPL78252">
        <property type="protein sequence ID" value="KPL78252"/>
        <property type="gene ID" value="ADN00_07210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.109.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029479">
        <property type="entry name" value="Nitroreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000415">
        <property type="entry name" value="Nitroreductase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00881">
        <property type="entry name" value="Nitroreductase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55469">
        <property type="entry name" value="SSF55469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitroreductase" evidence="2">
        <location>
            <begin position="7"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="Nitroreductase" evidence="2">
        <location>
            <begin position="81"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="173" mass="19121" checksum="D1509BA7990AE51A" modified="2016-01-20" version="1">MNAFEAILKRRSIRKFTEQPVSDADLLHLLKAAMAAPSATNARPWEFVVVTDAQVLAELKRVLILARFNAPAAVIVCGKPNSIAARRFWVQDCSAAMENMLVAAVEMGLGSVWVGIHPVHLFEQGVAKILGLPKDVTPMGMAYFGYPAEEKEPRTQYDESKVHWQKYGNPKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XF94</accession>
    <name>A0A0P6XF94_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_05300</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05300"/>
    <dbReference type="EnsemblBacteria" id="KPL78870">
        <property type="protein sequence ID" value="KPL78870"/>
        <property type="gene ID" value="ADN00_05300"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007318">
        <property type="entry name" value="Phopholipid_MeTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04191">
        <property type="entry name" value="PEMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="88"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL78870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="157" mass="17490" checksum="5513C37667BBE09E" modified="2016-01-20" version="1">MVFLSIPLTIFAVAQILLAFLLYNPQANETVINAGWAILFLSAVFGWLPIFTFRAKGGVKGRGYIQTTVLVDSGIYAIVRHPQYLAGILINIALALISQHGLVALTGVAAAVLYYLGIFDEEKGCIEKFGEEYIQYMKRVPRINFILGIFRILLNRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XFH6</accession>
    <name>A0A0P6XFH6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Putative [LysW]-aminoadipate semialdehyde transaminase</fullName>
            <ecNumber evidence="2">2.6.1.118</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">lysJ</name>
        <name evidence="4" type="ORF">ADN00_06680</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the transfer of the amino group of L-glutamate to [LysW]-aminoadipate 6-semialdehyde, generating [LysW]-gamma-L-lysine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>2-oxoglutarate + [amino-group carrier protein]-C-terminal-gamma-(L-lysyl)-L-glutamate = [amino-group carrier protein]-C-terminal-N-(1-carboxy-5-oxopentan-1-yl)-L-glutamine + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:41952"/>
            <dbReference type="Rhea" id="RHEA-COMP:9714"/>
            <dbReference type="Rhea" id="RHEA-COMP:9715"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:78501"/>
            <dbReference type="ChEBI" id="CHEBI:78526"/>
            <dbReference type="EC" id="2.6.1.118"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
        <text evidence="2">Binds 1 pyridoxal phosphate per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-lysine biosynthesis via AAA pathway; L-lysine from L-alpha-aminoadipate (Thermus route): step 4/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.118" evidence="2"/>
    <dbReference type="EMBL" id="LGCL01000018">
        <property type="protein sequence ID" value="KPL78407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06680"/>
    <dbReference type="EnsemblBacteria" id="KPL78407">
        <property type="protein sequence ID" value="KPL78407"/>
        <property type="gene ID" value="ADN00_06680"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00033">
        <property type="reaction ID" value="UER00038"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019878">
        <property type="term" value="P:lysine biosynthetic process via aminoadipic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02084">
        <property type="entry name" value="LysJ_aminotrans_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004636">
        <property type="entry name" value="AcOrn/SuccOrn_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037537">
        <property type="entry name" value="LysJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00707">
        <property type="entry name" value="argD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="1 2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="2">
        <location>
            <begin position="108"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="2">
        <location>
            <begin position="220"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="276"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="277"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL78407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="389" mass="41187" checksum="E8E730038F8B4B01" modified="2016-01-20" version="1">MMETMLDIKALEGQYSSGIYAKRDLVITRGSGALLYDEQGSEYIDCVGGQGTANVGHCQPTVIAAIQEQIQKLMICPEMFHNPTRAQFQARLCGLVPGMQRAYLCNSGTEAVEAAIKFARYSTGRPGIVAAMRGFHGRTLGSLSATWNKKYRDGFEPLVPGFSHVPYDNLEKLQEAVNDSTAAVLLEVVQGEGGVYPGSAEFLQGAQEICRQRGALLIIDEVQTGFGRTGQMFAFQHHGLQPDLVAMGKSIAAGIPMGAVLLGERVTQLSPGVHGSTFGGNPVACAAGLAVLDLLEGQQLPQRAARLGKALMDEIAALNLPAVREVRGKGLMIGIETRGKVAGLLGALAEKGVLALPAGLTVIRLLPPLVISGEQLQTVKQALIEVLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGX6</accession>
    <name>A0A0P6XGX6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Cysteine--tRNA ligase</fullName>
            <ecNumber evidence="11">6.1.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Cysteinyl-tRNA synthetase</fullName>
            <shortName evidence="11">CysRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">cysS</name>
        <name evidence="13" type="ORF">ADN00_14010</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + L-cysteine + tRNA(Cys) = AMP + diphosphate + L-cysteinyl-tRNA(Cys)</text>
            <dbReference type="Rhea" id="RHEA:17773"/>
            <dbReference type="Rhea" id="RHEA-COMP:9661"/>
            <dbReference type="Rhea" id="RHEA-COMP:9679"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78517"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="11">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 11">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.16" evidence="11"/>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063652.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000033.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14010"/>
    <dbReference type="EnsemblBacteria" id="KPL74149">
        <property type="protein sequence ID" value="KPL74149"/>
        <property type="gene ID" value="ADN00_14010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1901"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004817">
        <property type="term" value="F:cysteine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006423">
        <property type="term" value="P:cysteinyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00672">
        <property type="entry name" value="CysRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00041">
        <property type="entry name" value="Cys_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015803">
        <property type="entry name" value="Cys-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015273">
        <property type="entry name" value="Cys-tRNA-synt_Ia_DALR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024909">
        <property type="entry name" value="Cys-tRNA/MSH_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032678">
        <property type="entry name" value="tRNA-synt_1_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10890">
        <property type="entry name" value="PTHR10890"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09190">
        <property type="entry name" value="DALR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01406">
        <property type="entry name" value="tRNA-synt_1e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00983">
        <property type="entry name" value="TRNASYNTHCYS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00840">
        <property type="entry name" value="DALR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00435">
        <property type="entry name" value="cysS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11 13" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="DALR_2" evidence="12">
        <location>
            <begin position="351"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="11">
        <location>
            <begin position="31"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="11">
        <location>
            <begin position="266"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="29"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KPL74149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="465" mass="52571" checksum="EF9D11187F3549CC" modified="2016-01-20" version="1">MSLRIYNTMSRQKEPFETLEPQKVRMYVCGPTVYNKAHVGHAMSALVFDILRRYLEYRGYSLTHVMNFTDVDDKIIRRANELGMDPFKLGQSYIDEYRQHLQDLNILAPTITPYATREIDQIIAMINGLIEKGYAYPVDGDVYFRVQKDNDYGRLSGRKLEDMQAGARIDVDERKENPMDFALWKSARPGEPAWDSPWGPGRPGWHIECSAMNLHHLGEQIDIHGGGNDLIFPHHENEIAQSESLTGKTFARYWVHNGMLQFGGEKMSKSLGNLVTIEEFLEKHNADVLRFLVLNSGYRNPLTFNDEVLAQAERALERLRSGLKAALPGAKGADASALENLEKQTAASKDGFIESMDDDFNSAGALGYLFDLVRVINQARDASASAEQLQPAQALLRELTGVLGLRLEEKENGNQAAGPFIDLLIEVRSEMRKNKLWALSDLVRDRLAELGVKLEDSRDGTTWHW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGY4</accession>
    <name>A0A0P6XGY4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_03875</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061651.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03875"/>
    <dbReference type="EnsemblBacteria" id="KPL79038">
        <property type="protein sequence ID" value="KPL79038"/>
        <property type="gene ID" value="ADN00_03875"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.129"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11754">
        <property type="entry name" value="GH94N_CBP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009342">
        <property type="entry name" value="Carb-bd_put_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033432">
        <property type="entry name" value="GH36_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037825">
        <property type="entry name" value="GH94N_CBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037018">
        <property type="entry name" value="Glyco_hydro_65_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010383">
        <property type="entry name" value="Glyco_hydrolase_94"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17167">
        <property type="entry name" value="Glyco_hydro_36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06165">
        <property type="entry name" value="Glyco_transf_36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01068">
        <property type="entry name" value="CBM_X"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CBM_X" evidence="2">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="814" mass="91841" checksum="B0925AD45D348461" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-12-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XH39</accession>
    <name>A0A0P6XH39_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Tyr recombinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_02560</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000012">
        <property type="protein sequence ID" value="KPL79419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061394.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000012.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79419">
        <property type="protein sequence ID" value="KPL79419"/>
        <property type="gene ID" value="ADN00_02560"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyr recombinase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="210" mass="23505" checksum="0A6C66005E3B0EE0" modified="2016-01-20" version="1">MLFLSGMRASAFTTLPIEAVDLDNLRLRQWPELGVHTKNGKKATTFLLNIPEILAPVRQWDAIVRKSLPGSSPWYAPIAHSWGDQFLSQDEPGKTRSQALQKRLELLFSIANLEFKSPHKFRHGHAVYGLLHAQTMADYKAVSMNLMHESIEITDSTYAPMLSSDVQERIAGLSGKATSMPGDELEVFLNKLDRESQKKALMFIAGKLAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XIF1</accession>
    <name>A0A0P6XIF1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SAF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_02355</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000010">
        <property type="protein sequence ID" value="KPL79660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061354.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000010.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02355"/>
    <dbReference type="EnsemblBacteria" id="KPL79660">
        <property type="protein sequence ID" value="KPL79660"/>
        <property type="gene ID" value="ADN00_02355"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013974">
        <property type="entry name" value="SAF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08666">
        <property type="entry name" value="SAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00858">
        <property type="entry name" value="SAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SAF" evidence="1">
        <location>
            <begin position="347"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="448" mass="48484" checksum="3E339D139ED92399" modified="2016-01-20" version="1">MIGLNEELRERHAAGNPVRIGLIGAGQMGTDVVAEVSMMLGVEVVVTADVDLERARKAYEIGQVKAEVVVAQTAEEADAAVRAGKVVAATDYHVVTQMKTVQVMLEATGVPEIGTRAALLSARSGQHLSMMNVETDITVGPVLRWYAERKGVLYALAAGDEPAACKELYDFAEALGFTIVAAGKGKNNPLDRHATPVDPVIAKEAARRGLSPNMLVEFVDGSKTMIEMAAVANATGLVPDVRGMHGPDTDRDHLSETFRLKEEGGVLNKMGVVDYGIGRVAPGVFLVIRTDHPRLREAMVLRDMGNGPYYTLFRPYHLCSIEVPLTCAMLEIRKKPNMVPLNRLAAEVFAVAKHDLKPGDVLDAIGGTAYYSLVDTYETARAERLLPIGLAKGARVIRDIPVDQPITLDDVELKPSTVLELRKLQDQWFAGKVSDDELEKAIDGLALE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XII8</accession>
    <name>A0A0P6XII8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Aminotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_02090</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000008">
        <property type="protein sequence ID" value="KPL79931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061307.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000008.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02090"/>
    <dbReference type="EnsemblBacteria" id="KPL79931">
        <property type="protein sequence ID" value="KPL79931"/>
        <property type="gene ID" value="ADN00_02090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2849"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024169">
        <property type="entry name" value="SP_NH2Trfase/AEP_transaminase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000524">
        <property type="entry name" value="SPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="3">
        <location>
            <begin position="30"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000524-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL79931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="364" mass="38670" checksum="973ABE643B43A533" modified="2016-01-20" version="1">MQTYPISMTPGPVKVPPEILAVWQTDFGSGDLETEYLELYNRTETNLQAILGTKNKVTIHTGEGMLGLWGALKSCLLPGDRVLSISTGVFGSGIGEMAKTVGAEVRLIELPFNQTLNGLEAVDRAIREFKPKMITVVHCETPSGTLNPIHELGALKHSLGVPLLYVDAVASAGGAPVDADACHIDLCLGGSQKALSVPPSMTFVSVSDAAWEIIQQVNYAGYDAFLPFYTAQKNFYFPYTPYWHGTAALNAGAELLLKEGLQNAYARHEAVAQACRAGIEELGLELFPAPGAVSSPTVTAVNVPQGIPWPELDARLRAGGLVVGGSYGPMAGKVFRLGHMGSQADLNLLEQALGVIRGAVKDIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XIQ2</accession>
    <name>A0A0P6XIQ2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sugar ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_13530</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13530"/>
    <dbReference type="EnsemblBacteria" id="KPL74862">
        <property type="protein sequence ID" value="KPL74862"/>
        <property type="gene ID" value="ADN00_13530"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1199"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="16"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="79"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="154"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="269"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="72"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL74862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="303" mass="34057" checksum="E1A19D742F137D80" modified="2016-01-20" version="1">MPKKGSRNSRHANDRLVIVLFLLPALVIFLLFVIYPIFRSVYYSTFDWKGLGAAVNNVGLGNYKKVLDDVVFLKSVKNVLIIIVLSLAVQLPAAIVLATMVGRDLPGRALFRTTFFLPYVLSEVNTGIMWMLLYNPDPERGFINGILVQLGLSPVNWLADMNVVLIAVFIALTWKYFGFHLLLYLTGLQNIPLEIEEAARMDGANSIQNFFFITLPLLGSTIKTSVYMSVLGSIQQFILVWVMTRGGPVNASETMATYMYRFGFVRFQFGYGSAVAIIMFIICVIFSLVYLQLTRKPDYLTGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XJE5</accession>
    <name>A0A0P6XJE5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_16835</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064216.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL71371">
        <property type="protein sequence ID" value="KPL71371"/>
        <property type="gene ID" value="ADN00_16835"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL71371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="74" mass="8523" checksum="8B269807EE212E6C" modified="2016-01-20" version="1">MAYEAWVKIKSRYCDRAGCKVSLEAHMVFPASWMPETPPRRVGLRCNHGMICNEKEQTACRWSGTNPAYDPFLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XJQ4</accession>
    <name>A0A0P6XJQ4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_11650</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063190.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11650"/>
    <dbReference type="EnsemblBacteria" id="KPL76011">
        <property type="protein sequence ID" value="KPL76011"/>
        <property type="gene ID" value="ADN00_11650"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01125">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="312" mass="32794" checksum="E4F91F327940CE43" modified="2016-01-20" version="1">MKTIIAADIGGTGIRVAVYPFSGSTEPLAQKRIPTRGEGTAVERLVGLIRELWPAGHEVAGISAGFPGPVNPYEGIIYTAPNIADWKNLPLGQILSDTFHVPAMVGNDANMACLGEWKFGAAQGHRDVIYITISTGIGTGVISNNQLLLGAKGLATEMGHTVVNPEGPLCGCGHPGHIESYSSGTGITSFVKSQLAAGRESSLRGISRLSAKEIAEAAVTGDSLAKEAFEIAGTYLGIGISNFLHIFNPSIIVLGGGVSQTGSLILDPMRRSLKERVVSEEYIKDLVITPAQLQDNCGLLGCLAWAQINFKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XK40</accession>
    <name>A0A0P6XK40_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01440</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061182.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01440"/>
    <dbReference type="EnsemblBacteria" id="KPL80537">
        <property type="protein sequence ID" value="KPL80537"/>
        <property type="gene ID" value="ADN00_01440"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1042"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="11"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="178" mass="21012" checksum="224A8946D928D281" modified="2016-01-20" version="1">MNFEPFETQRLALRRFQPQDWQMVYEYMSSPAVTAYLPDGQFSEDQARELVTEGTSDYEESIAVMLKEENALVGHMMFHPWFGPNTYEIGWVFHTRYHNRGFATEAATALLKYGFETLKLHRVIATCQPENTASVRVMEKLGMRREGHFQKCLHLSGERWWDEYFYAMLEEEWFAAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-12-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XL52</accession>
    <name>A0A0P6XL52_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF5655 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062888.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76943">
        <property type="protein sequence ID" value="KPL76943"/>
        <property type="gene ID" value="ADN00_10150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043714">
        <property type="entry name" value="DUF5655"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18899">
        <property type="entry name" value="DUF5655"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5655" evidence="1">
        <location>
            <begin position="7"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="126" mass="14259" checksum="FEE884A8BEEB1B70" modified="2016-01-20" version="1">MPAPTLDEFFNGFPASRPLFDALLSAAEELGEVELTVQKSQIVLRRARPFAWVWVPGRYLRGRTAPLVLSLSFPAPDPSPRWKEIVQVSRARFMHHLELRSAAEIDAEVRAWLRQGWQAAGRDLPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XLW8</accession>
    <name>A0A0P6XLW8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Integrase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_09270</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the transposase IS21/IS408/IS1162 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062710.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77309">
        <property type="protein sequence ID" value="KPL77309"/>
        <property type="gene ID" value="ADN00_09270"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4088"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032196">
        <property type="term" value="P:transposition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017894">
        <property type="entry name" value="HTH_IS21_transposase_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50531">
        <property type="entry name" value="HTH_IS21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0814">Transposable element</keyword>
    <keyword evidence="3" id="KW-0815">Transposition</keyword>
    <feature type="domain" description="HTH IS21-type" evidence="6">
        <location>
            <begin position="5"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="Integrase catalytic" evidence="7">
        <location>
            <begin position="111"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL77309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="390" mass="45222" checksum="639C70914860A791" modified="2016-01-20" version="1">MLRKEDYRMIDLLKQKGLYLKDIADGLGVSSRTVRRALKRGGPPPRERKRARSKLDAYKQTVDRLLSEGVWNAQVILREIQNEGYVGGYTILREYIQPKRPLRASRATVRFETTPGQQMQSDWGEVIVQIANQPTKVYFCVNELSYSRRFHFWCTNSQDSEHTYEGIIRSLEYFGGTTEEVLVDNQKATVLEHPANGKPYFNARFLDMADHYGLTPKACKPYRARTKGKDERMVGYIKGNFFVRYRAFESWAHLNQLAELWLAQEADQRVQGTVKEVVAERFQREKPALKPLPSLRYDTSYYEFRRVAWDGYIDVRGNRYSVPAELVGQGVAVRIGLDGNLRVFQAETLVAQHLLRSKQAGWSTVMSHHRELWEAVKVEQRSLEAYEEVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XMH7</accession>
    <name>A0A0P6XMH7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_19000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064617.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70128">
        <property type="protein sequence ID" value="KPL70128"/>
        <property type="gene ID" value="ADN00_19000"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3111"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133128" evidence="2">
        <location>
            <begin position="25"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="471"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="471"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL70128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="572" mass="61785" checksum="040746D70E7051B1" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XMQ3</accession>
    <name>A0A0P6XMQ3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Chaperone protein HtpG</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Heat shock protein HtpG</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">High temperature protein G</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">htpG</name>
        <name evidence="7" type="ORF">ADN00_00990</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Molecular chaperone. Has ATPase activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the heat shock protein 90 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061084.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00990"/>
    <dbReference type="EnsemblBacteria" id="KPL81128">
        <property type="protein sequence ID" value="KPL81128"/>
        <property type="gene ID" value="ADN00_00990"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3597"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00505">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019805">
        <property type="entry name" value="Heat_shock_protein_90_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037196">
        <property type="entry name" value="HSP90_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001404">
        <property type="entry name" value="Hsp90_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020575">
        <property type="entry name" value="Hsp90_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11528">
        <property type="entry name" value="PTHR11528"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00183">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002583">
        <property type="entry name" value="Hsp90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00775">
        <property type="entry name" value="HEATSHOCK90"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110942">
        <property type="entry name" value="SSF110942"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00298">
        <property type="entry name" value="HSP90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 5" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="A; substrate-binding" evidence="5">
        <location>
            <begin position="1"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="C" evidence="5">
        <location>
            <begin position="545"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="472"/>
            <end position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL81128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="619" mass="71436" checksum="241811200BC6861B" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XN05</accession>
    <name>A0A0P6XN05_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Aspartokinase</fullName>
            <ecNumber evidence="12">2.7.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">ADN00_08010</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>ATP + L-aspartate = 4-phospho-L-aspartate + ADP</text>
            <dbReference type="Rhea" id="RHEA:23776"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57535"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 13">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; (S)-tetrahydrodipicolinate from L-aspartate: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 13">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 1/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 13">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 1/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 12">Belongs to the aspartokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.4" evidence="12"/>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062467.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08010"/>
    <dbReference type="EnsemblBacteria" id="KPL77821">
        <property type="protein sequence ID" value="KPL77821"/>
        <property type="gene ID" value="ADN00_08010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.602"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00015"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00461"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00462"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004072">
        <property type="term" value="F:aspartate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005260">
        <property type="entry name" value="Asp_kin_monofn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001341">
        <property type="entry name" value="Asp_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018042">
        <property type="entry name" value="Aspartate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027795">
        <property type="entry name" value="CASTOR_ACT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13840">
        <property type="entry name" value="ACT_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000726">
        <property type="entry name" value="Asp_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00657">
        <property type="entry name" value="asp_kinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00324">
        <property type="entry name" value="ASPARTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 12 15" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="7 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACT" evidence="14">
        <location>
            <begin position="412"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="237"/>
            <end position="238"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="248"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="273"/>
            <end position="274"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000726-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KPL77821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="471" mass="49774" checksum="F2F021DD030298A3" modified="2016-01-20" version="1">MQSNQETLVMKFGGTSVGSADAMAQVVQIALEARKSWSKVILVTSALSGVTNLLLDSASQAVNGDTQTYTQAVFNLRQKHFEIADQLITNLARRDQVKQEINHLISEFSNLCHAISVLGEASPRALDAVAALGERMSVRLLAAATESAGQPAQFVEASQLIVTDRQFQSAHPIMEASREKMRAVLNPILDEGAIAVVTGFIAATEDGIITTLGRGGSDYSAALVGALLPSQEVWIWTDVDGVMTADPRLVPDAHTIPTLSYREVAELAYYGAKVLHPLTIRPVVEAGVGLRVLNTFNPANPGTEIVRDMQTDSGKVIKAVTAIKGLRLITVDGRGMLGVPGVAARTFGTVAATGISVPLISQASSEQSICFAVPAESADEVVAALQNTFAREIERRDIDRIWATHNVGTITVVGAGMSSTPGVAGKVFSALGSNQVNVIAIAQGSSEVSISLMVTEEEIKRAVVTLHSLIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XNH2</accession>
    <name>A0A0P6XNH2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_07825</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000020">
        <property type="protein sequence ID" value="KPL78077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062432.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000020.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07825"/>
    <dbReference type="EnsemblBacteria" id="KPL78077">
        <property type="protein sequence ID" value="KPL78077"/>
        <property type="gene ID" value="ADN00_07825"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2856"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015315">
        <property type="entry name" value="DUF1963"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035948">
        <property type="entry name" value="YwqG-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09234">
        <property type="entry name" value="DUF1963"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103032">
        <property type="entry name" value="SSF103032"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="267" mass="31075" checksum="841922D14ADDBFDE" modified="2016-01-20" version="1">MVEVDLPSDLLIYKEKIEATIKPFIEIKTKAVDNLSLWQSKFGGFPYFPKGLQYPTDSKGQAMFLLAQINFGETPKLSPFPEIGILQFYISNASDVYGACFESPAKQEDFRIMYFPEVTEDESFLVSKFDFLPKPDVLPIEKQSALSFSLKHAPMSVVDYHFEPTILTIDPKMKYELFKEYQKVYEEYEKLFRSDGHKIGGYPYFTQNDPREFEIYKEEELMLLFQMDTDDEAGIMWGDCGVANFFISEQDLLSKNFSRVLYNWDCC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XNX0</accession>
    <name>A0A0P6XNX0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Response regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_07425</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062349.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07425"/>
    <dbReference type="EnsemblBacteria" id="KPL78287">
        <property type="protein sequence ID" value="KPL78287"/>
        <property type="gene ID" value="ADN00_07425"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017746">
        <property type="entry name" value="Cellulose_synthase_operon_BcsQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06564">
        <property type="entry name" value="CBP_BcsQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="3"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="410" mass="45455" checksum="2E1F864F630652F2" modified="2016-01-20" version="1">MARILVIDDEPIYHQMIDHALRPLGYEVYFALDGMQGLNAASALEPDVVITDVMMPGMSGYEVARQLRKNPRFTLTPILVLTSRSELGDKLSAFESGSDDYMSKPFDPEELVARMTVLLRRADLLRNVKDVEKVKIEQARLIGVHSLRGGVGCSSIAVNLAIAFWEIWQKPTLIVDSVMTAGSVALMLNAPMKRTWADLAQISPADLDIEALKSIIGAHKHGLHFITGPARPAEAEMVPNDTLRSAINILRTKYEYMVIDIPHDFSETSIHMLDAVDTILLVLAPEMASIRGAAVALDTYDKLGYKMDKIQLVLNHVAESTGLTARKIEDALNVKIRLEIPFASQDFIRAINIGKPLLYGGTNPDVSGLLEDAAFRLSKESHRKVAPTHPSVAWRQVQKRISQERERSEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XNY2</accession>
    <name>A0A0P6XNY2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_07570</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062373.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78305">
        <property type="protein sequence ID" value="KPL78305"/>
        <property type="gene ID" value="ADN00_07570"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="233"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="275"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="306"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="335"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="361"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="410" mass="45232" checksum="830ECB5856DC9329" modified="2016-01-20" version="1">MNKTWFVLKNEFIRIVTRRSFLLALVLIPLVSFVAMWAVGKLRGTEAENTIANVFSDEGNLPEMEGYIDFSGLLKEEDPDLRERFVRYEDEETAKADLQAGKIAAYYVITAGYVETGEVFYYRPDFNPLAAFDEASGLRAALQSSLAAEDPVIAERLANPLVLERKYLKPQSQRDEDNLMTFFLPYGVTMLFYVMVMSSSSTMLNSISDEKQNRVMEILLSSVRPIQLLTGKIIALGLVGLLQSVVWGGAGLLLLRLGGQTFNLPEEFQLPPQILVWFVVFFILGYAIYASLLGGLGALVPNIKEASQVTFIIMMPMIVPLMLISALINRPNAALSVFLSLFPLSSPMAMMTRMAATDVPLWQTGLAVALLAVTCVLTVRASAGMFRAQNLIAGQKADVKTFLLALLGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XP49</accession>
    <name>A0A0P6XP49_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_10725</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 66 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062993.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10725"/>
    <dbReference type="EnsemblBacteria" id="KPL77029">
        <property type="protein sequence ID" value="KPL77029"/>
        <property type="gene ID" value="ADN00_10725"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14745">
        <property type="entry name" value="GH66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025092">
        <property type="entry name" value="Glyco_hydro_66"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13199">
        <property type="entry name" value="Glyco_hydro_66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="528" mass="58677" checksum="66C4BB9C94FE052A" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XPA4</accession>
    <name>A0A0P6XPA4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">50S ribosomal protein L10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_17695</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the universal ribosomal protein uL10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000043">
        <property type="protein sequence ID" value="KPL70915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17695"/>
    <dbReference type="EnsemblBacteria" id="KPL70915">
        <property type="protein sequence ID" value="KPL70915"/>
        <property type="gene ID" value="ADN00_17695"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05797">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1730">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043141">
        <property type="entry name" value="Ribosomal_L10-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001790">
        <property type="entry name" value="Ribosomal_L10P"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11560">
        <property type="entry name" value="PTHR11560"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00466">
        <property type="entry name" value="Ribosomal_L10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160369">
        <property type="entry name" value="SSF160369"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL70915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="167" mass="17903" checksum="574972F1CF0DAB70" modified="2016-01-20" version="1">MVAEYSELLQKSQAVFIIEHGKMNMKEIDTFRAKVREAGGVAHICKNTLFTIALKEQGYEVKSKLAGTSLVGFALQDAPALAKAFDEITAKSEIFALKKGFLDNKEISAQQIKALADLPPLPVMRATLLGTIMAPASQLVRTLAEPARGLAAVIKAYSEKDSAPAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XPL5</accession>
    <name>A0A0P6XPL5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_14060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063661.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000033.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14060"/>
    <dbReference type="EnsemblBacteria" id="KPL74123">
        <property type="protein sequence ID" value="KPL74123"/>
        <property type="gene ID" value="ADN00_14060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003749">
        <property type="entry name" value="ThiS/MoaD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02597">
        <property type="entry name" value="ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="SSF54285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL74123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="89" mass="9660" checksum="5FD37302603FEC4F" modified="2016-01-20" version="1">MAHENGLIHVQVVFYAHLKTAAGVASTQVELERGATVADLKTVLKQRYPALSYQLVNTVTFINKQTLYLDSESLPDAAEVTFLPPMAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XPM6</accession>
    <name>A0A0P6XPM6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">GTP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_14165</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063680.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000033.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14165"/>
    <dbReference type="EnsemblBacteria" id="KPL74141">
        <property type="protein sequence ID" value="KPL74141"/>
        <property type="gene ID" value="ADN00_14165"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1934"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021147">
        <property type="entry name" value="DUF697"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05128">
        <property type="entry name" value="DUF697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G" evidence="2">
        <location>
            <begin position="28"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL74141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="369" mass="39282" checksum="A006EEFADF4836D5" modified="2016-01-20" version="1">MSVKLENDFAELLKQKLEEALNQRGKVNIVVAGKTGVGKSTLVNAVFQGNLAETGDGRPVTKTTREINKEGIPLSIFDTRGLEVSEYHNTVHDLEKLIQDKKKSKDPNQHIHIAWVCVMEGSRRVEDAEIKLVEMLDKYIPVVGVITKSMSDSGFRHTVQELLPQTRNVVRVLAKETVFDGGYTIPAMGLDNLVELTMTLVPETQRDALAAAQKVSLNHKLQRAHTVVGGAAITAGGAGAVPLPFSDALAIIPIQISMLASISAVWGLPISTAFLGTLVSGAITGSAGTLVGRATAGALLKLIPGIGSTAGGAISAGVASTLTIAFGEAYITALYVLTKDDPSRIPTAEEIRDEFMRQLKSLKKEPAVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQ42</accession>
    <name>A0A0P6XQ42_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Phosphate transport system permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">ADN00_17485</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064336.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17485"/>
    <dbReference type="EnsemblBacteria" id="KPL71472">
        <property type="protein sequence ID" value="KPL71472"/>
        <property type="gene ID" value="ADN00_17485"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.564"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011864">
        <property type="entry name" value="Phosphate_PstC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02138">
        <property type="entry name" value="phosphate_pstC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="15"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="68"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="267"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="72"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL71472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="302" mass="32467" checksum="2728C121411786D0" modified="2016-01-20" version="1">MASKAKRINHYSEAVITAIIRTAGYLSVLFVALISFFLFREAIPVVFKIPAGTLLNTRWYPIEGLYGLLPLLLGSLTITLGASLIAIPLGLLTAVYISEIAPPWTKEILKPMVEILAGIPSVVLGFLGILVLSPFLRETFNLPTGLTALAGSILLGWAAIPTIVSVSEDALNTVPASFREASLALGCTRWQTIWGVTVPSARSGIITAIMLGVGRVIGETMTVMMVTGNAPTMPAGLRTILLPIRTMTATIASEMGEVAKGSDHYQVLFFIGLILFLFSLIINIVAFQISARRVKRSERLLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQ47</accession>
    <name>A0A0P6XQ47_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">16S rRNA (guanine(1405)-N(7))-methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.179</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">16S rRNA m7G1405 methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_17540</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>guanosine(1405) in 16S rRNA + S-adenosyl-L-methionine = N(7)-methylguanosine(1405) in 16S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42772"/>
            <dbReference type="Rhea" id="RHEA-COMP:10225"/>
            <dbReference type="Rhea" id="RHEA-COMP:10226"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:74480"/>
            <dbReference type="EC" id="2.1.1.179"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyltransferase superfamily. Aminoglycoside resistance family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.179" evidence="3"/>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71481.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064347.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL71481">
        <property type="protein sequence ID" value="KPL71481"/>
        <property type="gene ID" value="ADN00_17540"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008649">
        <property type="term" value="F:rRNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025981">
        <property type="entry name" value="rRNA_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010769">
        <property type="entry name" value="rRNA_MeTrfase_GmN_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07091">
        <property type="entry name" value="FmrO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015852">
        <property type="entry name" value="RRNA_mtase_Grm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="8">
        <location>
            <begin position="97"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="8">
        <location>
            <begin position="177"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00015154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00033062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR015852-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL71481.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="271" mass="30456" checksum="8623C3FC759D4503" modified="2016-01-20" version="1">MNGADDLERLVQAVMASPRYAALSEELVRSVGARELQKRRNFKEAVKQTRSKLHQVGAAYQEDNMQYAAWEQELERLPSSVESTELRAFCLRVMAAHASTRERLPILEAFYQELLDHLPPARSLLDVACGLNPLCLPWMKLEENAQYYACDVYTDMVAFLNRFLAHVGAGGGAQVCDLTARVPDVEVDLALVLKTLPCLEQLDKTITPRLLQGLRAKSIVVSFPAHSLGGRSKGMAQFYERQFLQQVEGLPFKASALRFKTELAFLLERVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQY0</accession>
    <name>A0A0P6XQY0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Beta-ketoadipyl CoA thiolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_05105</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061875.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05105"/>
    <dbReference type="EnsemblBacteria" id="KPL79220">
        <property type="protein sequence ID" value="KPL79220"/>
        <property type="gene ID" value="ADN00_05105"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.391"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00751">
        <property type="entry name" value="thiolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020615">
        <property type="entry name" value="Thiolase_acyl_enz_int_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020610">
        <property type="entry name" value="Thiolase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020613">
        <property type="entry name" value="Thiolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01930">
        <property type="entry name" value="AcCoA-C-Actrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00098">
        <property type="entry name" value="THIOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00737">
        <property type="entry name" value="THIOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00099">
        <property type="entry name" value="THIOLASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase_N" evidence="5">
        <location>
            <begin position="5"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase_C" evidence="6">
        <location>
            <begin position="277"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-thioester intermediate" evidence="3">
        <location>
            <position position="89"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="355"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000429-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL79220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="406" mass="43051" checksum="2ED4E79EC9F62D7B" modified="2016-01-20" version="1">MPEAVIIDAVRTPIGNLGGALAGIRPDDLAALVLQALARRSGLDPALVEEVYLGCANQAGEDNRNVARMASLLAGFPVHVAGVTVNRLCASGLTAVNMAARAIRCGEGEVFIAGGVESMSRAPYVVSKAERGYAFGNLTLWDTALGWRLPNPKMEISYGTHPLGETAERIADAYAIRREEQDAFALESHRRAIAAMDSGRFEAEIEPVPVPQRKGEALLVTQDERPRRDTSLDSLARLKPAFRPDGTVTAGNSSGMNDGAAALLMMSAERARQLGLRPMARVVASAAAGVQPDMMGMGPVPAVGKLLQRSGLSIEQIGLFEVNEAFAVQSLAVMRELKMPVERTNVNGGAVALGHPLGCSGARILTTLLHEMRRRAPGQVRPFYGLAALCVGVGQGEASLVEWLED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQY3</accession>
    <name>A0A0P6XQY3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_08750</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000022">
        <property type="protein sequence ID" value="KPL77669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062614.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000022.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08750"/>
    <dbReference type="EnsemblBacteria" id="KPL77669">
        <property type="protein sequence ID" value="KPL77669"/>
        <property type="gene ID" value="ADN00_08750"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1467"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043755">
        <property type="term" value="F:alpha-ribazole phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006003">
        <property type="term" value="P:fructose 2,6-bisphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003094">
        <property type="entry name" value="6Pfruct_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001345">
        <property type="entry name" value="PG/BPGM_mutase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017578">
        <property type="entry name" value="Ribazole_CobC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00991">
        <property type="entry name" value="6PFRUCTKNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03162">
        <property type="entry name" value="ribazole_cobC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00175">
        <property type="entry name" value="PG_MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL77669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="195" mass="21420" checksum="3BC720FBC94D04FD" modified="2016-01-20" version="1">MTVLYLIRHGQTDWNLQGRYTGQSDIPLNATGEQQARAAAAQLAGVKLDAIVASDLQRARHTAEIIAAQMGLPVQTDPRLREIHQGVWEGMHFAEIKTHYEEAFQRRKRNPLGVAPPGGETVGQVQTRVLAALRDICAQYPHQQVAVVSHGLSLAIIKASLSGHPIQRVWELIPPNAQVERLPMGCEDRPRPGGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-08-12" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQZ2</accession>
    <name>A0A0P6XQZ2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_04200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ROK (NagC/XylR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79238">
        <property type="protein sequence ID" value="KPL79238"/>
        <property type="gene ID" value="ADN00_04200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="393" mass="41580" checksum="0DA3D6D41F6BD496" modified="2016-01-20" version="1">MFIQLIRRFDGSSKEELVDYTGYSRSKVNRVIQSLLDKRIIVETGKSKNTGGRRAVIFSLNGQLGLVAGVYVGATSIDLVLTDLSGRWLARSSEVAFVKDGPYKTLDRISEIIGQMVSSNGYTNEDVIGMGIGVPGPVDFSLGSLISPTIMPGWDKFPVVPYIHQAFPKAYVVVDNDVNMMAVGELIKGVGKGVKNLIFAKIGTGIGAGIICEGKIYRGTYGCAGDIAHICVDKNGPICVCGNTGCLEALAGGPAIANQGVKAIQEGRQTVLSEYYKRNNGSLTSIDIGNAAREGDAVAIEIIRNSGRIIGEVIAGLVNFFNPGMIIIGGGVSKLGNLFLSSIRQSILKRSLPLATRDLSILFSDLGDDAGVIGAVSMAMDMMFAAYADAPLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XR08</accession>
    <name>A0A0P6XR08_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Galactokinase</fullName>
            <ecNumber evidence="10">2.7.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Galactose kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">galK</name>
        <name evidence="14" type="ORF">ADN00_15960</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the transfer of the gamma-phosphate of ATP to D-galactose to form alpha-D-galactose-1-phosphate (Gal-1-P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>alpha-D-galactose + ATP = ADP + alpha-D-galactose 1-phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13553"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28061"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58336"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="10">Carbohydrate metabolism; galactose metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the GHMP kinase family. GalK subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.6" evidence="10"/>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL71993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064036.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15960"/>
    <dbReference type="EnsemblBacteria" id="KPL71993">
        <property type="protein sequence ID" value="KPL71993"/>
        <property type="gene ID" value="ADN00_15960"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3625"/>
    <dbReference type="UniPathway" id="UPA00214"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004335">
        <property type="term" value="F:galactokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006012">
        <property type="term" value="P:galactose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00246">
        <property type="entry name" value="Galactokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000705">
        <property type="entry name" value="Galactokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022963">
        <property type="entry name" value="Galactokinase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019539">
        <property type="entry name" value="GalKase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006203">
        <property type="entry name" value="GHMP_knse_ATP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006206">
        <property type="entry name" value="Mevalonate/galactokinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10457:SF6">
        <property type="entry name" value="PTHR10457:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10509">
        <property type="entry name" value="GalKase_gal_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08544">
        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000530">
        <property type="entry name" value="Galactokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00473">
        <property type="entry name" value="GALCTOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="SSF55060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00131">
        <property type="entry name" value="gal_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00627">
        <property type="entry name" value="GHMP_KINASES_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="1 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 10" id="KW-0299">Galactose metabolism</keyword>
    <keyword evidence="5 10 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="7 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GalKase_gal_bdg" evidence="13">
        <location>
            <begin position="13"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP_kinases_N" evidence="11">
        <location>
            <begin position="118"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP_kinases_C" evidence="12">
        <location>
            <begin position="280"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="37"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="175"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="125"/>
            <end position="131"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="10">
        <location>
            <position position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00246"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF08544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF10509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KPL71993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="386" mass="41940" checksum="F559EFC4AFF170BD" modified="2016-01-20" version="1">MQNQSPFESVKTAFERIYVEKPAFVVRAPGRVNLVGEHTDYNDGFVFPMAIDSGVWIALRPRVDRKVVIQSLDFNETIAFDLLQLEAEKPVKPAEYMKGVAWALTQAGYDLTGFEGCMQGNVPIGAGLSSSAALEVATARAFAVVSGFSWDAARMAQLSQKAENEWVGMNCGIMDQMISAAGKAGSALLIDCRTLEFEVAPIPSNAVVVVLDTSTRRGLVDSAYNERRAQCEAAARYFDVKALRDVSVERLLAEGSGLDQVTFRRARHIVTENARTLEAKQAMQADDAAWLGRLMKASHASLRDDFEVSSPALDTMVDLANDFRGCFGARMTGAGFGGCAVALVDRNKAERFVNYISPAYRHATGNSPQIYVTQPAEGASVVEERG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XR74</accession>
    <name>A0A0P6XR74_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_16595</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064185.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16595"/>
    <dbReference type="EnsemblBacteria" id="KPL72121">
        <property type="protein sequence ID" value="KPL72121"/>
        <property type="gene ID" value="ADN00_16595"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3761"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="65"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="88"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="155"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="208"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="265"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL72121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="310" mass="32726" checksum="56E4C58DD9FC3866" modified="2016-01-20" version="1">MKRFYWRDYVVYITFIIIFVTFSISLFDDGFLSSNNLLNIMRQTATISVMAVAMTFVLASAEIDLSVGAVAGLASVITAIIIGRFGLFAGIVAGLITGALIGILNGALITRVGIPSFLVTLGMQGIATGTAMWITDTAPIPIANKTYTHFFGSGNFGPVPSLIVWTLLALVIGHIVFRHTPFGRQVLATGGNETAARYSGINTKNIKFYTFILMSTVAALAGMLYAGRLHSGRFQWGEGDELSVIAAVVLGGTSLFGGKGSVIGTIIGAILIGLINNGLILMGLDASQQMIIRGAIIILAVALTGRKQQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XSI5</accession>
    <name>A0A0P6XSI5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_02395</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000010">
        <property type="protein sequence ID" value="KPL79677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79677">
        <property type="protein sequence ID" value="KPL79677"/>
        <property type="gene ID" value="ADN00_02395"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="162" mass="18328" checksum="1501005FF778AD2F" modified="2016-01-20" version="1">MGNHRMTARSERFSQLEQSVTHLLEVMDSLPDPLLEVYPGWSAKDVLGHLVGWHESFARNTRDLSLGVQPKPLKGRLQDLNDQFAAESRVLDVPALAARLRAAQTLLGEHILNPRVEIIPYRVGSRSYSPEDHLEIVRQHILHHIGDIQKVVGRQARRAAQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XSX1</accession>
    <name>A0A0P6XSX1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_06965</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062261.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06965"/>
    <dbReference type="EnsemblBacteria" id="KPL78217">
        <property type="protein sequence ID" value="KPL78217"/>
        <property type="gene ID" value="ADN00_06965"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007165">
        <property type="entry name" value="Phage_holin_4_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37309">
        <property type="entry name" value="PTHR37309"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04020">
        <property type="entry name" value="Phage_holin_4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="127" mass="13811" checksum="0396D64AC23F0C15" modified="2016-01-20" version="1">MKLILRLAINAIALYTAIYLVDGIVPQSENWVSLIWLALIFGLVNAILKPVLTVAGCGFIILTLGLGTLIINTFLFWLAGVIGQQFGVGFTVTGFGAAFLGALITSVVSFILSQFLIDDRERKHKRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-08-12" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XSX6</accession>
    <name>A0A0P6XSX6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_11855</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063228.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76043">
        <property type="protein sequence ID" value="KPL76043"/>
        <property type="gene ID" value="ADN00_11855"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="19"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="106"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="226" mass="25397" checksum="35903CEF6D9CC482" modified="2016-01-20" version="1">MDKKQLLLRLRRKKMGLLIADARQAAGRSLNDCARAMGVSQDQLKAIETGQCSPSLPELEAFSFYLNLPVEHFWGSQPYKPLEESSKEETPDPSHAARNEEISQLLRARREEAGLSLEQLSQQTFLPLETLQTYEAGEEQIPVPELEFIAQEIGLRMEDLIDPSGQPGNWRAQIGSARPLLELPDDVKKFISQPTNLPYIELAMRLSSLSSDRLRSIAEGILEITL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XTZ0</accession>
    <name>A0A0P6XTZ0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">ADN00_06630</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetyl-CoA + H2O + S-adenosyl-L-methionine + uridine(34) in tRNA = 5'-deoxyadenosine + carboxymethyluridine(34) in tRNA + CoA + 2 H(+) + L-methionine</text>
            <dbReference type="Rhea" id="RHEA:61020"/>
            <dbReference type="Rhea" id="RHEA-COMP:10407"/>
            <dbReference type="Rhea" id="RHEA-COMP:11727"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74882"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="1">
            <dbReference type="Rhea" id="RHEA:61021"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">tRNA modification.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the ELP3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000017">
        <property type="protein sequence ID" value="KPL78592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06630"/>
    <dbReference type="EnsemblBacteria" id="KPL78592">
        <property type="protein sequence ID" value="KPL78592"/>
        <property type="gene ID" value="ADN00_06630"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2834"/>
    <dbReference type="UniPathway" id="UPA00196"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039661">
        <property type="entry name" value="ELP3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034687">
        <property type="entry name" value="ELP3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032432">
        <property type="entry name" value="Radical_SAM_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11135">
        <property type="entry name" value="PTHR11135"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16199">
        <property type="entry name" value="Radical_SAM_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00344">
        <property type="entry name" value="ELP3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01211">
        <property type="entry name" value="ELP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="12" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="12" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="13">
        <location>
            <begin position="317"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KPL78592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="459" mass="51782" checksum="67FD45B58D5D6FD0" modified="2016-01-20" version="1">MKPGRTLSGVTTVTVLTKPFPCPGHCIFCPDDTRMPKSYLPDEPGAARAFQNEFDPYRQVRSRIEAYEAVGHPTDKIELLILGGSWSAYPRAYQEQFIRRCFDAMNEADTATLEEAQRVNESAPHRNVGLVIETRPDQISRDELMWLRRLGVTKVQMGAQSLDDDILKLNKRGHSTAELRRAVALLRAGGFKIVLHWMPNLLGATLATDRADFARLWAERGEGAGYCPDEIKIYPTQLLEKTELHQHWERGEYRPYTTEELVNLIADVKPSIPVYCRVNRIIRDIPSTHVVEGNRRTSLRQDALEELKRRGQRCQCVRCREVRGQKVNPEHLEKRDTVYQAAQAEEHFLQMVTPDDRLAGFLRLSLPDEGAPDLALDDLRGAALIREVHVYGQSLEVGAEVEGAAQHIGLGTALLAWAGEIARAKGYARLAVIAAIGTRKYYESRGFTRGDLYMVKPVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XU53</accession>
    <name>A0A0P6XU53_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_09790</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062819.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76884">
        <property type="protein sequence ID" value="KPL76884"/>
        <property type="gene ID" value="ADN00_09790"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="176" mass="19330" checksum="FC5C4A60FBCF0A92" modified="2016-01-20" version="1">METFISAIASYLQQAGCVLDSYSAPYGVHALLYARSARRVQLGFAKVEDHFLFVDWERSDIRNIPGLKALYAHFSTFANQSYKTPHALRTQIPNLALVAVSRTEFAPEIITFAQSTSLEPWYGGEAGQLILVELERQQVISLASLSSGRHPRPGALPLGHAAQVIRAACGQAFKRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUB9</accession>
    <name>A0A0P6XUB9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_05725</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062009.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78739">
        <property type="protein sequence ID" value="KPL78739"/>
        <property type="gene ID" value="ADN00_05725"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1621"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01547">
        <property type="entry name" value="SBP_bac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133232" evidence="2">
        <location>
            <begin position="31"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="459" mass="49330" checksum="917ED5F38C3013A5" modified="2016-01-20" version="1">MSKSKFWYLTMALVLAASMLLVACQPAAPAAPAEQPAAEQPAAEQPAAEQPTAVPAATEQPAEAPAAEASKLEIFSWWTAGGEAEGLNAMFEVYSAKYPEVEIINATVAGGAGTNAKAVLATRLQGGDPPDSFQVHAGLEVEKYEPTTYLQPIDDMFDPSVFPADLLKMLEYEGHYWSMPVNIHRSNVLWYNKTVFEENGLEVPTTIDEFFAACDTLKAAGIIPVTMGTKDGWEAAHVFEGMLAATLGADDYRGIWTGEVPWTDPRVTEALEYFQRMMTYVNEDHAALTWDGAGEYMLSNQAAMMIMGDWAAGWFASKGYSDFGWAATPGSGGIFVGLSDSFALPQGAPNEAEARHWLEVCGSKEGQEAFNPKKGSICARTDCDPEAFKVVPETYEYLTSAAEDWATNAIVPSVVHGAASIESWATDFKDTITLFVSSGDVAGTQAALQGLCVDAEVCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XVD1</accession>
    <name>A0A0P6XVD1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SBP_bac_5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_05010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05010"/>
    <dbReference type="EnsemblBacteria" id="KPL79205">
        <property type="protein sequence ID" value="KPL79205"/>
        <property type="gene ID" value="ADN00_05010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.371"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002741">
        <property type="entry name" value="MppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SBP_bac_5" evidence="2">
        <location>
            <begin position="65"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="568" mass="63577" checksum="9A84898316F4BE03" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XVF4</accession>
    <name>A0A0P6XVF4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_04315</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase A31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04315"/>
    <dbReference type="EnsemblBacteria" id="KPL79241">
        <property type="protein sequence ID" value="KPL79241"/>
        <property type="gene ID" value="ADN00_04315"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008047">
        <property type="term" value="F:enzyme activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06067">
        <property type="entry name" value="H2MP_MemB-H2evol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004420">
        <property type="entry name" value="Pept_A31_hyd_mat_HycI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023430">
        <property type="entry name" value="Pept_HybD-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000671">
        <property type="entry name" value="Peptidase_A31"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30302">
        <property type="entry name" value="PTHR30302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01750">
        <property type="entry name" value="HycI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00446">
        <property type="entry name" value="HYDRGNUPTAKE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53163">
        <property type="entry name" value="SSF53163"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00072">
        <property type="entry name" value="hydrog_prot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="153" mass="16083" checksum="4AE1AD6CDD8E9FCE" modified="2016-01-20" version="1">MKSPAPNQPDPRVVILGVGNELNGDDRAGVAVAEFLQAQLNNPRFLVLNGGNAPENYVGKVIKFAPQVVLLIDAADLGEPPGAVRLVEWDETQGLSASTHSLPPSVMAKYLIAELGCQVLVLAIQAGSLELMQPLTPPVAQAVGEIVETLSQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XW41</accession>
    <name>A0A0P6XW41_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Haloacid dehalogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_08625</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000022">
        <property type="protein sequence ID" value="KPL77652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062591.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000022.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08625"/>
    <dbReference type="EnsemblBacteria" id="KPL77652">
        <property type="protein sequence ID" value="KPL77652"/>
        <property type="gene ID" value="ADN00_08625"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016070">
        <property type="term" value="P:RNA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033956">
        <property type="entry name" value="Translin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002848">
        <property type="entry name" value="Translin_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036081">
        <property type="entry name" value="Translin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10741">
        <property type="entry name" value="PTHR10741"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10741:SF2">
        <property type="entry name" value="PTHR10741:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74784">
        <property type="entry name" value="SSF74784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="15"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="213" mass="24274" checksum="5D4E61F96974958D" modified="2016-01-20" version="1">MKNLQTIADQVVEVFEELTHARDQALINARQLTRKSAHTIRAIHRLEREEAQSLLAEACELQHKLNTDLANYPTLLYAGYTMDAIKEFVEASITYALIVDDPLPTPQDLGVEPATYLNGLAEVTGELRRRVLDILRHGYSEEAERLLTIMDEIYSVLVTIDYPDAITNGLRRQTDLVRGIVERTRGDMTIALQEERLKQSMEALQNRLDEANR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XW70</accession>
    <name>A0A0P6XW70_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000003">
        <property type="protein sequence ID" value="KPL80811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061110.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000003.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80811">
        <property type="protein sequence ID" value="KPL80811"/>
        <property type="gene ID" value="ADN00_01050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="210"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="253"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="287"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="333" mass="36856" checksum="148B27BC117B8581" modified="2016-01-20" version="1">MEQKTETATAQPPRLVSSLGAGFNTVANSLYLILFPVILDLFLWVGPRLSLKQAMETLLSNTFVTLQEMGSPEMLEILTTTEKTWQTILQYFNLFSSLRSFPIGVGSLLAGQPAGDSPLGARAVIELPSLSAAVGWWAALAVVGVILGSVYFSEVARFCTGEQTPFSFKNLQWQTFHSLAFSIGLVVLIVLVSFPVSIMVSIIGMINATFAQIAIFAIIFFVLWLLLPLFFVPHGIFLRKLNILKSILNSVRLVRFVLPSTSLFILVIVLLSQGMNLIWLIPPVDSWMTLVGILGHAFVTTGLLAASYIYYRDGSQWMEESIQRLMQQRSQKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XW97</accession>
    <name>A0A0P6XW97_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glyco_trans_2-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_08755</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000022">
        <property type="protein sequence ID" value="KPL77688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08755"/>
    <dbReference type="EnsemblBacteria" id="KPL77688">
        <property type="protein sequence ID" value="KPL77688"/>
        <property type="gene ID" value="ADN00_08755"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1468"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="37"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="332" mass="37946" checksum="367CB8724A49A854" modified="2016-01-20" version="1">MSILVDRWFAENTFSATEFENLEKLLALKQERGLTISVALPALNEEKTVGNVITCIQKNLMQDVPLLDELVLIDSDSEDRTREIAAGLGVPVYIHQQILPQYGARRGKGEALWKSLYVTSGDILLWVDTDIVNFHPRFVYGLIGPLLHSPRWKFVKGFYRRPLRGEDGQLHPGRGGRVTELTARPLINLFYPQLSGIIQPLAGEYGGRREVLERVQFTSGYGVEISLLIDVFEQFGLDAIAQVDLEERVHTNQPLDKLSKMSFAIIQTVIHKLEKRFGTELVKNINRTMKTMHYEPDYFYLEVDEIAERFRPLMIELPEYRQQRGLDETAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XY23</accession>
    <name>A0A0P6XY23_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Pyridoxal phosphate homeostasis protein</fullName>
            <shortName evidence="1">PLP homeostasis protein</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_00070</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL80988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00070"/>
    <dbReference type="EnsemblBacteria" id="KPL80988">
        <property type="protein sequence ID" value="KPL80988"/>
        <property type="gene ID" value="ADN00_00070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3410"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02087">
        <property type="entry name" value="PLP_homeostasis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011078">
        <property type="entry name" value="PyrdxlP_homeostasis"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10146">
        <property type="entry name" value="PTHR10146"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004848">
        <property type="entry name" value="YBL036c_PLPDEIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00044">
        <property type="entry name" value="TIGR00044"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01211">
        <property type="entry name" value="UPF0001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ala_racemase_N" evidence="4">
        <location>
            <begin position="15"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="1 2">
        <location>
            <position position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR004848-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL80988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="244" mass="27396" checksum="07A88E0B3DE15F9D" modified="2016-01-20" version="1">MGKMSLSNDIHARIQAVQEKIEKAAARCGRDAGDVTLVVVTKAQPVEVVQAVIDAGARVLGENYPEETTEKIPHLNIPETLSWHMIGHLQSRKSKLVAEHFHYLQSLDSLSLARKLDRHLEEAGRKMDVLLECNVGEEETKHGWGVSSSSELNSFYADIEAISKLPNLRIRGLMCMPPLFEDAELARPYFLRLRRLRDDLRRDYPMLDWSALSMGTSVDYTVAIEEGATFVRVGTAIVGPRHYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XY68</accession>
    <name>A0A0P6XY68_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">RNA methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_14005</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063651.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000033.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14005"/>
    <dbReference type="EnsemblBacteria" id="KPL74115">
        <property type="protein sequence ID" value="KPL74115"/>
        <property type="gene ID" value="ADN00_14005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="L30e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004441">
        <property type="entry name" value="rRNA_MeTrfase_TrmH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013123">
        <property type="entry name" value="SpoU_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46429">
        <property type="entry name" value="PTHR46429"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08032">
        <property type="entry name" value="SpoU_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00967">
        <property type="entry name" value="SpoU_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="SSF55315"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00186">
        <property type="entry name" value="rRNA_methyl_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SpoU_sub_bind" evidence="1">
        <location>
            <begin position="4"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="246" mass="26917" checksum="FCE38A467B50D331" modified="2016-01-20" version="1">MKEWITGRNPIYEALQARRRHFFRLRVAKGIEEKGRVVEIIRTIRGFRLPIEVVERRVLDPLGENHQGMALEASDYPYAVLKDIFERAEKRGEPLFVLLLDVLQNPQNLGTLIRTAEAVGVHGVVIPPNRAAGVTPAVVTASAGATEHMLVAQSNLAQAMQAIKDANGWVVGLEGSPDAQPIEKLRLDGPLGLVVGSEGEGMRALVRKNCDQLLKLPMVGRIESLNAAVAGSVVLYLAYQARSPQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XZ50</accession>
    <name>A0A0P6XZ50_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_06815</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0394 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000018">
        <property type="protein sequence ID" value="KPL78429.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062229.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000018.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78429">
        <property type="protein sequence ID" value="KPL78429"/>
        <property type="gene ID" value="ADN00_06815"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2276"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026366">
        <property type="entry name" value="Seleno_YedE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007272">
        <property type="entry name" value="Sulf_transp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04143">
        <property type="entry name" value="Sulf_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04112">
        <property type="entry name" value="seleno_YedE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="94"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="129"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="199"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="240"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="271"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="313"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="350"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="domain" description="Sulf_transp" evidence="8">
        <location>
            <begin position="221"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL78429.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="374" mass="38899" checksum="340BC8334C7EC175" modified="2016-01-20" version="1">MSERLTRFFASRRGIVLVGAIIGALGSLLQKLGNPPNMGICVACFERDIAGALGLHRAIAVQYIRPEIIGFVLGSLIAALVFREFKARAGSAPLVRFVLGAFAMIGALAFLGCPWRANFRLAGGDLTALPALVGLAVGIWLGVIFLKNGYNLGRSQKTYAAVGWIFPLLMVGLLLLAVIQPVFAEGGPIFNTPEGKGPGALHAAWGISLGVGLVIGFLAQRTRFCTMGSVRDVILMGDTHLISGLGALLVTAFLTNLAFGQFHPGYTAQPVAHSNLIWNVLGMVLSGLAYALAGGCPGRQLFLTGEGDSDAGVFVLGMIVGAGFSHNFGLAGTPDKLVEGTLQVGGLTPAGMAAVILGIVVCILIGFSMREKLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y2C9</accession>
    <name>A0A0P6Y2C9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_04245</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061715.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04245"/>
    <dbReference type="EnsemblBacteria" id="KPL79087">
        <property type="protein sequence ID" value="KPL79087"/>
        <property type="gene ID" value="ADN00_04245"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.206"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="58"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="162"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="257"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="297"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL79087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="323" mass="34181" checksum="D9594CAB57B92F5E" modified="2016-01-20" version="1">MGNLLKKINWEKVKQFNSKYSYLVSFIGLLIFATIINPRYFSYRNLSTLMLQASIKGIITLGMSILIIAGMIDLSVGSLVALVAGLSVVVLNTTGNVWLMLLFCIIFGAILGSMNGLLVTKGKIAPFIVTLATMSAFRSVIVQLGQGGPFNVAADILPSFRMIAAGDVLGIPNLALIFAVMTVIIAVLMAKTKFGRYVYAVGSNEQAARLAGINVDQIKTLAFTITGLLTGIAAFLLTSRLTSITAPNAGQSFELDAIAAVAIGGIAMTGGRGVIAGSFFGAIMLQMIEGILIAAKIPPFLNGLVKGVIIIFTVLLQRKKNND</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y2L8</accession>
    <name>A0A0P6Y2L8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cyclic nucleotide-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_04795</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061817.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04795"/>
    <dbReference type="EnsemblBacteria" id="KPL79169">
        <property type="protein sequence ID" value="KPL79169"/>
        <property type="gene ID" value="ADN00_04795"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="1">
        <location>
            <begin position="11"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="163" mass="17810" checksum="33939CBBB487AA75" modified="2016-01-20" version="1">MFRQDFSQLAIFDGLTTGQLSQLEPFFERVHFKAGQIVFDQGSDANHLYILLTGKVEVVYKPYDGPPLTVARINDGGVFGWSAALGREAYTSAAISTENGEAIRLSVANLRQLCEKSPQIGSAFLDRLAGVIAERIQNTHDQVLAILTQGMETNSDCQEEGEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y3B7</accession>
    <name>A0A0P6Y3B7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_12315</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76117">
        <property type="protein sequence ID" value="KPL76117"/>
        <property type="gene ID" value="ADN00_12315"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="69" mass="7688" checksum="7EA73534C8F5BB7A" modified="2016-01-20" version="1">MAAMERQNMQPLPESAVAEMLETPSPGCADPFPGEKAREGVKMRWLRWTVCWRAAYYAAPTEIRGCGDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y4S3</accession>
    <name>A0A0P6Y4S3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutamate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_11545</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Glu/Leu/Phe/Val dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76592.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11545"/>
    <dbReference type="EnsemblBacteria" id="KPL76592">
        <property type="protein sequence ID" value="KPL76592"/>
        <property type="gene ID" value="ADN00_11545"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033524">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006097">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02812">
        <property type="entry name" value="ELFV_dehydrog_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00074">
        <property type="entry name" value="GLFV_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ELFV_dehydrog_N" evidence="3">
        <location>
            <begin position="37"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL76592.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="161" mass="18342" checksum="8FDEC40C258D4A77" modified="2016-01-20" version="1" fragment="single">MSTKTNAFQMAQAQFDHVADLLALDPQVREFLRWPLREYHFRIPVRMDDGSMRLFEGFRVQHNDSRGPNKGGIRFHPDETADTVRALAMWMTWKCAVVDIPLGGGKGGVIVDPATLSPGEKERLVRGWVQQMWKNIGPRQDVPAPDVGTTPQMMGWMMDEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y631</accession>
    <name>A0A0P6Y631_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">PDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">ADN00_01250</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M50B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000003">
        <property type="protein sequence ID" value="KPL80843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061146.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01250"/>
    <dbReference type="EnsemblBacteria" id="KPL80843">
        <property type="protein sequence ID" value="KPL80843"/>
        <property type="gene ID" value="ADN00_01250"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041489">
        <property type="entry name" value="PDZ_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004387">
        <property type="entry name" value="Pept_M50_Zn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008915">
        <property type="entry name" value="Peptidase_M50"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42837">
        <property type="entry name" value="PTHR42837"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17820">
        <property type="entry name" value="PDZ_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02163">
        <property type="entry name" value="Peptidase_M50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="89"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="329"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="PDZ" evidence="10">
        <location>
            <begin position="107"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL80843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="356" mass="38308" checksum="E982593BE8286DFB" modified="2016-01-20" version="1">MIMIVEFILAFGILVFLHEFGHYMMARLSGVEVEEFGFGFPPRLTKLFTWKGTEFTLNWIPFGAFVRPKGENDPSVEGGMAAANPWKRLGILLGGPLMNLLTGIVLFSIVFGQTGVPDFSQVQVVDVSPNSPAEQAGMLPGDLIISINGQPVTSIENLAAVIGANAGKEITIEYLREGQAATITAVPRVNPPAGEGSFGISMSNPVIKAGITKTVPFAFRMTFEQGKQLLQLPGRLIRGEVSGEEARFVGPVGAYGLYEQAREMDEEMTATPQAETVPAVNTLALMGILAVALGLTNLLPIPALDGGRILFILPELVTGRRVRPELENLVNMVGFFALIALMIYVTAQDIINPIIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YB21</accession>
    <name>A0A0P6YB21_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glycerol kinase</fullName>
            <ecNumber evidence="5">2.7.1.30</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">ATP:glycerol 3-phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Glycerokinase</fullName>
            <shortName evidence="5">GK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 9" type="primary">glpK</name>
        <name evidence="9" type="ORF">ADN00_04500</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn-glycerol 3-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + glycerol = ADP + H(+) + sn-glycerol 3-phosphate</text>
            <dbReference type="Rhea" id="RHEA:21644"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17754"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.30"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="5">Inhibited by fructose 1,6-bisphosphate (FBP).</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Polyol metabolism; glycerol degradation via glycerol kinase pathway; sn-glycerol 3-phosphate from glycerol: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the FGGY kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.30" evidence="5"/>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061761.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04500"/>
    <dbReference type="EnsemblBacteria" id="KPL79125">
        <property type="protein sequence ID" value="KPL79125"/>
        <property type="gene ID" value="ADN00_04500"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.257"/>
    <dbReference type="UniPathway" id="UPA00618">
        <property type="reaction ID" value="UER00672"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004370">
        <property type="term" value="F:glycerol kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019563">
        <property type="term" value="P:glycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006072">
        <property type="term" value="P:glycerol-3-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00186">
        <property type="entry name" value="Glycerol_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000577">
        <property type="entry name" value="Carb_kinase_FGGY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="Carb_kinase_FGGY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018483">
        <property type="entry name" value="Carb_kinase_FGGY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018484">
        <property type="entry name" value="Carb_kinase_FGGY_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005999">
        <property type="entry name" value="Glycerol_kin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02782">
        <property type="entry name" value="FGGY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00370">
        <property type="entry name" value="FGGY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000538">
        <property type="entry name" value="GlpK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01311">
        <property type="entry name" value="glycerol_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00445">
        <property type="entry name" value="FGGY_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0319">Glycerol metabolism</keyword>
    <keyword evidence="5 6 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FGGY_N" evidence="7">
        <location>
            <begin position="4"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="FGGY_C" evidence="8">
        <location>
            <begin position="261"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="82"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="245"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="12"/>
            <end position="14"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="12"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="267"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="311"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="315"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="412"/>
            <end position="416"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL79125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="499" mass="54510" checksum="3941B9F7B0CE871D" modified="2016-01-20" version="1">MAKYAAAVDQGTTSTRFMIFDHSGKVVAVDQKEHEQIYPKPGWVEHNPMEVWERTQEVIEGALKKASIDPKDIAAIGITNQRETTVVWEKATGKPVYNAIVWQDTRTDTICNELAKDGGQDRFRTKVGLPLATYFSGPKIAWILANVPGVREKAEKGEVLFGNMDTWVIWNLTGGPKGGVHVTDVSNASRTMLMNLETLEWDEEILKIMGVPRAMLPKIMPSSAVYGHAANTGVAGVPVAGDLGDQQAALFGQTCYSVGEAKNTYGTGCFMLLNTGTRAVQSKNGLLTTLGYKIGDQPAVYALEGSIAITGALVQWLRDNLKMIEKSSDIEALAKTVDDAGGIYFVPAFSGLFAPYWKSDARGVIVGMTRYVTRGHIARAALEATAYQTREVLDAMNKDSGVELTALKVDGGMVFNELLMQFQADILGVPVIRPTVAETTALGAAYAAGLAVGFWAQVEDLRANWGKDREWKPQMNADTREAIYKGWKKAVTRTFDWIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GKK9</accession>
    <name>A0A0N8GKK9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Sulfur reduction protein DsrE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_18105</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL69986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064453.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18105"/>
    <dbReference type="EnsemblBacteria" id="KPL69986">
        <property type="protein sequence ID" value="KPL69986"/>
        <property type="gene ID" value="ADN00_18105"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2924"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027396">
        <property type="entry name" value="DsrEFH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003787">
        <property type="entry name" value="Sulphur_relay_DsrE/F-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02635">
        <property type="entry name" value="DrsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75169">
        <property type="entry name" value="SSF75169"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL69986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="118" mass="13189" checksum="D096898D7B1986FD" modified="2016-01-20" version="1">MKITIQVMVPPYTNQDLDTALNIAEACLDRGHEVRLFLFSDSILSTNTKVKPVRSDRNIPERMRLLIEEKKLRVDICGICMEYRGVRPEDAISGAAPSGLPELASLVVTSDRFVNLMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GL34</accession>
    <name>A0A0N8GL34_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Nuclease SbcCD subunit D</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">sbcD</name>
        <name evidence="8" type="ORF">ADN00_16930</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">SbcCD cleaves DNA hairpin structures. These structures can inhibit DNA replication and are intermediates in certain DNA recombination reactions. The complex acts as a 3'-&gt;5' double strand exonuclease that can open hairpins. It also has a 5' single-strand endonuclease activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 6">Heterodimer of SbcC and SbcD.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the SbcD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064233.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16930"/>
    <dbReference type="EnsemblBacteria" id="KPL71386">
        <property type="protein sequence ID" value="KPL71386"/>
        <property type="gene ID" value="ADN00_16930"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.445"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00840">
        <property type="entry name" value="MPP_Mre11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041796">
        <property type="entry name" value="Mre11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004593">
        <property type="entry name" value="SbcD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00619">
        <property type="entry name" value="sbcd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5 6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="7">
        <location>
            <begin position="1"/>
            <end position="234"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL71386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="411" mass="46065" checksum="A90728451FA36E81" modified="2016-01-20" version="1">MRILHFADAHIDISAHGRHDPATGLPIRVLDFLRALDTIVDTAIAEKVDLVLFAGDAYKDRTPVPTFQREWGKRIARLSAAGVPTLLLVGNHDLSPASGRAHALQEFATLQVPNVLVADRPTLYLPQDLFGLPLQIMALPWLSRSGLMAALQLNDLPIEQINEEMELKLTELVGFWWQKIDPSLPVVLTAHASVQGAVYGGERSVMLGSDLVLKGSLTRDPRLDYVALGHIHKPQDLNPGAHPPVIYPGSIERVDFGEAKDDKFFVIADVQRGATQVEWRKLEGRAFIDRSITLDSGKEVTRQILDCLGPRELLKDAIVRLVINYPRELEPLIDEASVRDYAAETFEFHFPRRPQAQARARLSQLDPTRQLSHHDLLEQYWRSVNIDKKEKEALQTLAAQIMSSPIVKEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GLB3</accession>
    <name>A0A0N8GLB3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_16120</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064069.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72018">
        <property type="protein sequence ID" value="KPL72018"/>
        <property type="gene ID" value="ADN00_16120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="13"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="193"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL72018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="381" mass="42347" checksum="1C2EF588DB99272C" modified="2016-01-20" version="1">MRKTLQITGDSPYGGAGYLILRWCQFLVVNGWQVDVLATNPQWVAMLKEIPGLKVIEDILIPRDISPLKDAQAFSKLIKLLRRTRYDVVHTYTATPGFVGRLAARAAGVPVIVHHQAGWTVTEFSTPLQRIIYTPLEYLAVAASTCSICVSHAVERQAYDLHIAPPKKLVVICNGINPQPFFEACQNGAREMFRGRLGIPDGHLLIGNTGRLAPQKDNQTLIEAMKIFQTLQPETPFTLLIAGEGQERAELERLVDSLGLAGRVKLLGFVEDIPTFLAGVDMFISPSLWEGLSISLLEAMAAAKPIITTTILPNAELIEHEVNGLLVSPRRPDQIAEAVQRLWQDRALAVRCGEAARQRVVDHYSIERMFNETLELYQVQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GLB6</accession>
    <name>A0A0N8GLB6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH luxR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_16280</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72042">
        <property type="protein sequence ID" value="KPL72042"/>
        <property type="gene ID" value="ADN00_16280"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3693"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041617">
        <property type="entry name" value="TPR_MalT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17874">
        <property type="entry name" value="TPR_MalT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="854"/>
            <end position="919"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL72042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="922" mass="102624" checksum="D9A80CDEF78636DD" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GLP9</accession>
    <name>A0A0N8GLP9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">LacI family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_14875</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000036">
        <property type="protein sequence ID" value="KPL73106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14875"/>
    <dbReference type="EnsemblBacteria" id="KPL73106">
        <property type="protein sequence ID" value="KPL73106"/>
        <property type="gene ID" value="ADN00_14875"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025997">
        <property type="entry name" value="SBP_2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13407">
        <property type="entry name" value="Peripla_BP_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peripla_BP_4" evidence="1">
        <location>
            <begin position="4"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL73106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="283" mass="30570" checksum="B2CD5AC1B032F8E0" modified="2016-01-20" version="1">MTETLASKGIEVLERNANEDANRSLEMVKDCITQGVDGIMLIPQDGESAVNIIGVANEAGIPIGIFNRPPSNDSNPAIVIVADNEAIAEDAVEYMAQQAQKLGRQVTPLIMVGDLGDPNAVGRRQGFMNVIEKYPDLWTTAPIEVPTKWDAAVAQAGLENAMQANPDVDFLFTSSDFMFPLIQGVLEPLGKWAKVGEENHVIMGGLDGDVTACRLLKEGWIDATGVQDLYFEADSLMTAMLSSIALGEKTPENWIDDPGFALTGGNLAEREMDMWGCKLLAEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMT0</accession>
    <name>A0A0N8GMT0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">30S ribosomal protein S8</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsH</name>
        <name evidence="7" type="ORF">ADN00_12535</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">One of the primary rRNA binding proteins, it binds directly to 16S rRNA central domain where it helps coordinate assembly of the platform of the 30S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 30S ribosomal subunit. Contacts proteins S5 and S12.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063356.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12535"/>
    <dbReference type="EnsemblBacteria" id="KPL76154">
        <property type="protein sequence ID" value="KPL76154"/>
        <property type="gene ID" value="ADN00_12535"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3988"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01302_B">
        <property type="entry name" value="Ribosomal_S8_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000630">
        <property type="entry name" value="Ribosomal_S8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035987">
        <property type="entry name" value="Ribosomal_S8_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11758">
        <property type="entry name" value="PTHR11758"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00410">
        <property type="entry name" value="Ribosomal_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56047">
        <property type="entry name" value="SSF56047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00053">
        <property type="entry name" value="RIBOSOMAL_S8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL76154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="137" mass="15203" checksum="3833631D9A22C98B" modified="2016-01-20" version="1">MSVNDPIADMLTRIRNGVMAGQSVVAMPSSKMKAEIARILKEEGYISDFEVADGEKPTFATLRVKLKYVGERRERRSVITGLERVSRPGRRVYTQKQDIPWILSGLGIAILTTPKGVMTGQRARKLGVGGEIICKVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GN38</accession>
    <name>A0A0N8GN38_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10645</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062978.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10645"/>
    <dbReference type="EnsemblBacteria" id="KPL77018">
        <property type="protein sequence ID" value="KPL77018"/>
        <property type="gene ID" value="ADN00_10645"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2603"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="310" mass="33776" checksum="A18A188DD6394527" modified="2016-01-20" version="1">MQYLITGAAGFLGSALSNQLVQDGHAVRGLDDLSTGDPTALLPEVRFTRGDINDRPKLWTLLQDVDCVYHLAARVLVQESVLYPREYNQVNVGGTVTLMEAMRDVGVRRVVFISSGAIYGNQSVQPVREKFAPRPHSPYAVSKLAAEYYVRTIGELWGMETVCLRVFNAYGPGQQMPPVYTPVIPNFLRQALMNGTLVIHGDGKQTRDYAYIDDVVRAMVAASTAPDIHHDIINVGSGVETSVLDLANLVCEVTGKQPEIVINPRNAGGPGRLCADLSLAREKLGFEPRLSLTAGLQLTLEKDARLSQSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GN70</accession>
    <name>A0A0N8GN70_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062674.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77274">
        <property type="protein sequence ID" value="KPL77274"/>
        <property type="gene ID" value="ADN00_09050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="82"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="197" mass="21655" checksum="F7E39C38E05B067D" modified="2016-01-20" version="1">MNSLRKLSVLIEEYTNIRNFVVMLVLFVLVTGTMEVCPFGSIHLRNISNGVGMLDMLSGGYSSSLVYSMFERIGEAGRIGYAQLLGLDIVFALVYMCLLSLLTTLLLRGSGIGKQWILLNLLPVARSGLDLLENGLLLTLLFSYPVRLELLVNIASTITIAKWVVYFIILALLAVLGIYAAIRKIVVRTRSRATPGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GN82</accession>
    <name>A0A0N8GN82_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09565</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062780.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09565"/>
    <dbReference type="EnsemblBacteria" id="KPL77370">
        <property type="protein sequence ID" value="KPL77370"/>
        <property type="gene ID" value="ADN00_09565"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4152"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="363" mass="39906" checksum="45803028F02E027C" modified="2016-01-20" version="1">MKIGIIGVGQIGKIHLQTYQSISGVEVVGIAGRDPKKTEKVAKDYNIPFWTINLHELLAIKDIDAVSICLHNNLHQPATLEALKAGKHVFCEKPMAGTYHDALMMYETAKRTEKKLSIQLSSLFTNETKAAKKIIEKGLLGHTYFACSAGFRRRGRPFVDGYGSPSFVQLSQAGGGALYDVGVYHIANILYLLNNPIPLRISGKTYQEVPIDPNHYRESGFDVEEFAVGLVHLEGGMALNIVEAWAANLDQFGGSYMLGSKGGLRLKPFGFFHSIQEMDINSVIDLESFGYRLHNVCNSGIAYDGPQQHWIEALRGNIPLLPTAEIALTTMLISEGIYLSNKLGREVTAEDVIKLSKSTANPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNW4</accession>
    <name>A0A0N8GNW4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">2-dehydropantoate 2-reductase</fullName>
            <ecNumber evidence="2">1.1.1.169</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Ketopantoate reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_03695</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>(R)-pantoate + NADP(+) = 2-dehydropantoate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:16233"/>
            <dbReference type="ChEBI" id="CHEBI:11561"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15980"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.169"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; (R)-pantothenate biosynthesis; (R)-pantoate from 3-methyl-2-oxobutanoate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the ketopantoate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.169" evidence="2"/>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03695"/>
    <dbReference type="EnsemblBacteria" id="KPL79226">
        <property type="protein sequence ID" value="KPL79226"/>
        <property type="gene ID" value="ADN00_03695"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.91"/>
    <dbReference type="UniPathway" id="UPA00028">
        <property type="reaction ID" value="UER00004"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008677">
        <property type="term" value="F:2-dehydropantoate 2-reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003710">
        <property type="entry name" value="ApbA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013752">
        <property type="entry name" value="KPA_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013332">
        <property type="entry name" value="KPR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02558">
        <property type="entry name" value="ApbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08546">
        <property type="entry name" value="ApbA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00745">
        <property type="entry name" value="apbA_panE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0566">Pantothenate biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ApbA" evidence="3">
        <location>
            <begin position="4"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="ApbA_C" evidence="4">
        <location>
            <begin position="175"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL79226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="310" mass="32454" checksum="83F45750862575C7" modified="2016-01-20" version="1">MDLLIYGSGALACLFAFRLARAGQRVGILDHWEEGVRAIQAKGICQQTGDLAVSCQPVPATSSAQDLSNVPAAIVLVKSWQTAQAAADLAACLAPSARVLTLQNGLGNAEILAGALGAERVAAGSTTSGATLLAPGCFRPGGEGNLTLPASFESTRLCAALRAAGFQLAFTQQLTGLLWGKLLINAAINPLTALLEVPNGQILELPHARRLLAMAVEEAAQAARAAAVELPYTDPLAEVESVLRRTATNQSSMLQDIRRGAPTEIDAITGALLHSARQNQLWLPTHETLYHLVRAKVDAGRLADTLPNHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNW7</accession>
    <name>A0A0N8GNW7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_04865</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="8">Binds 2 divalent metal cations per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase M42 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04865"/>
    <dbReference type="EnsemblBacteria" id="KPL79250">
        <property type="protein sequence ID" value="KPL79250"/>
        <property type="gene ID" value="ADN00_04865"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008007">
        <property type="entry name" value="Peptidase_M42"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023367">
        <property type="entry name" value="Peptidase_M42_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05343">
        <property type="entry name" value="Peptidase_M42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001123">
        <property type="entry name" value="PepA_GA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="213"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="184"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="214"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="327"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR001123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001123-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001123-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL79250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="363" mass="39032" checksum="5B9F5E3918C5B668" modified="2016-01-20" version="1">MSLTNPSNTNVQPSAQQIALLERLSNACAVSSDEHEVRQIVRAEIEAHADEIIVDAMGNLLAVRRAQVENPLRVMLAAHMDEVGLMLIHSDGDGLFSFQTMGGIDPRQLVGKPVWVGRQHHPGVIGARPYHLSSDEEMRHSVPISQLRIDLGPGGSELAQPGDLAAFATRFQQAGPSLMGKALDDRLGVASLIEIFKTAPRHIELWAAFTVQEELGLRGARVAAFRIQPHLAIAVDSTPANDLPAADGQENTRYNTRLGFGPAIYVADRATISDPRLVRHLTETAAAQGIPFQYRQPGGGSTDAGAILRAQSGVPVISVSVPGRYAHTACLVARAADWGATMALLQASLQTLTTDILKEERRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GPK1</accession>
    <name>A0A0N8GPK1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_00955</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061076.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL81122">
        <property type="protein sequence ID" value="KPL81122"/>
        <property type="gene ID" value="ADN00_00955"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL81122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="69" mass="7745" checksum="D04068CD17B22412" modified="2016-01-20" version="1">MLHVFSRLIDRLSNFFAARKGLLPILGMLLIVVNFILRHLSSGWLADSDLFLHLGTLIALLGFLLAWAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WMM6</accession>
    <name>A0A0P6WMM6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Regulatory protein RecX</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">recX</name>
        <name evidence="5" type="ORF">ADN00_18440</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Modulates RecA activity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the RecX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064518.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18440"/>
    <dbReference type="EnsemblBacteria" id="KPL70039">
        <property type="protein sequence ID" value="KPL70039"/>
        <property type="gene ID" value="ADN00_18440"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006282">
        <property type="term" value="P:regulation of DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01114">
        <property type="entry name" value="RecX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003783">
        <property type="entry name" value="Regulatory_RecX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33602">
        <property type="entry name" value="PTHR33602"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02631">
        <property type="entry name" value="RecX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00018111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL70039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="215" mass="25257" checksum="77F5D26649C6CFB7" modified="2016-01-20" version="1">MMERKVTKIQVQKKNPNRVNIFLDEEFAFGLSRVVAAWLKVGDLISDEKIARLKQEDEYETAMQRALHFLGYRPRSEHEVRARLAENEYDAAVIEKVIERLRELKYVGDLDFARQWIENRSTFRPRGSRALAAELKQKGVEEKTIEQALMEMPEEEQLALEAARRYSARLHGLDRKAFRMRLGGFLGRRGFGYEIIYKVVDEIWQDLQSEDAQYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WPV0</accession>
    <name>A0A0P6WPV0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_16660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72100">
        <property type="protein sequence ID" value="KPL72100"/>
        <property type="gene ID" value="ADN00_16660"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132571" evidence="1">
        <location>
            <begin position="35"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="128" mass="13917" checksum="A8879F5B50FE93D8" modified="2016-01-20" version="1">MPNPRTKAQLRKPIWLLVLVLLVLSACSPPPVEKAAPAPQPGKCVVSGRVTNIQDFWQETSLSVYLADYYENDSGKGFFTLDAYAEPAGQVDEDGWFVLADLAPGNYVLVVGPSPADQSLDLGEIRLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WVW0</accession>
    <name>A0A0P6WVW0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_18700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064559.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18700"/>
    <dbReference type="EnsemblBacteria" id="KPL70078">
        <property type="protein sequence ID" value="KPL70078"/>
        <property type="gene ID" value="ADN00_18700"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3049"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="SSF54106"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="2">
        <location>
            <begin position="79"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="2">
        <location>
            <begin position="152"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL70078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="340" mass="35892" checksum="ED5C9F1592F12886" modified="2016-01-20" version="1">MVKAPKLPELTLSLPLVLGLIVIFMAIGAGVVFTVLRSSGRVVEPTVTPTVTVTPTITVTPTATATATPEPTWTPLPPIEYTIAAGDFCSSIAAFFNVSIQSIVVLNNLPADCGVLSVGQKLLIPQPTPTASPQPTQTLSGVAATEDACEKYSYTVNENDTLMGIANSFNVSMEAIKEFNSLPSDVVYSGQALLIPLCRRNPTPGPTPTATLPPPYPAPNLLLPTDGESFAGSSQTITLQWASVGTLRTGEAYAVTIEDVTAGTNLKVVEYVTDTKLIVPASMRPTDNAPHIIRWYVNAVRQSGTTQDGEPLWVSFGKTSEQRVFSWTGSGSTAETPAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WVY2</accession>
    <name>A0A0P6WVY2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_18915</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064602.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70115">
        <property type="protein sequence ID" value="KPL70115"/>
        <property type="gene ID" value="ADN00_18915"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038666">
        <property type="entry name" value="SSP1_head-tail_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="118" mass="13000" checksum="4BED6C8BBA8B17BD" modified="2016-01-20" version="1">MLTEEELSQIQIDINASFPETCEIYHQVFISDGAGGKKSDWAITVTTGGRIGPVGRDPVERVLAEKVSNSQPYVITMPAGTVVSETDQIHIGERIFEVVGVIQRSLETARRVICKEVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WX90</accession>
    <name>A0A0P6WX90_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_17715</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000043">
        <property type="protein sequence ID" value="KPL70883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70883">
        <property type="protein sequence ID" value="KPL70883"/>
        <property type="gene ID" value="ADN00_17715"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2134"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003735">
        <property type="entry name" value="Metal_Tscrpt_repr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038390">
        <property type="entry name" value="Metal_Tscrpt_repr_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33677">
        <property type="entry name" value="PTHR33677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02583">
        <property type="entry name" value="Trns_repr_metal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="101" mass="11377" checksum="F615D95B997E02E2" modified="2016-01-20" version="1">MRRKSGAAVKMQDPQVQKQLISRLRRIEGQVRGVQTMIDENRDCHEIMQQMAAIRSAVQSASQAMLEEFSENCLINLAGTDDLQERKLLLKDLIALIGKAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WXW3</accession>
    <name>A0A0P6WXW3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Flavodoxin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_16700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064189.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16700"/>
    <dbReference type="EnsemblBacteria" id="KPL71349">
        <property type="protein sequence ID" value="KPL71349"/>
        <property type="gene ID" value="ADN00_16700"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="1">
        <location>
            <begin position="3"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL71349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="156" mass="16613" checksum="9C37954587A4514A" modified="2016-01-20" version="1">MQIGIILYSQTGHTRRVALLTQDKLNASGHAVTLHTLESVGQPGFSQDAQAPLQSIPSVEAYDALIFATPVWGGHPAPPFLTFLNHTPGLQGKRVACLVTGFFPAQWGCVQAIAKMSEIAQSKGAQILGSASVSWFSLTRGRQIQQAAENLSALFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WY06</accession>
    <name>A0A0P6WY06_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_14600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000035">
        <property type="protein sequence ID" value="KPL73568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063768.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000035.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL73568">
        <property type="protein sequence ID" value="KPL73568"/>
        <property type="gene ID" value="ADN00_14600"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL73568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="163" mass="17118" checksum="E5910DC75DCAEE43" modified="2016-01-20" version="1">MSTADLLNRDNGEETEPISGVTYSRSRVRLGLSTTLAGLLIFLLGARPGIFGLDRSPVIGFVQIAVFLVGMAIICVGGYMSLMALWKGRTPSIAADIGLRLVSTGYVVAVFAGMADVFGFGSHPLPEVPYFGPLQARGVVIGEIIIGIGFLLLLPPGPKVKEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WYT6</accession>
    <name>A0A0P6WYT6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cupin_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_14335</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000034">
        <property type="protein sequence ID" value="KPL73769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL73769">
        <property type="protein sequence ID" value="KPL73769"/>
        <property type="gene ID" value="ADN00_14335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="1">
        <location>
            <begin position="29"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL73769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="115" mass="12522" checksum="EF30C2684260A257" modified="2016-01-20" version="1">MPADDTAKYATGKVVIGGQDGAENFVFRYFCVQPGGNSTMPDQHVHDHGIYFLHGKGEVTLNGVVYPVQARDMVYIAPNDVHGIINTGDEPLGFICVIPAKERLQEYLKLTGKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZ58</accession>
    <name>A0A0P6WZ58_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Methionine gamma-lyase</fullName>
            <ecNumber evidence="4">4.4.1.11</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_16375</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.11" evidence="4"/>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064116.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16375"/>
    <dbReference type="EnsemblBacteria" id="KPL72053">
        <property type="protein sequence ID" value="KPL72053"/>
        <property type="gene ID" value="ADN00_16375"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3716"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018826">
        <property type="term" value="F:methionine gamma-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00614">
        <property type="entry name" value="CGS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808">
        <property type="entry name" value="PTHR11808"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00868">
        <property type="entry name" value="CYS_MET_METAB_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL72053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="412" mass="44998" checksum="22E7370D618F68FE" modified="2016-01-20" version="1">MQDFDAQHGFSTLVNHVGEGNHPYNAHIMPLVQSSTFGFPDVDTGAARFKGEAPGYIYSRLSNPNLDQTARKIAILEGIDLLRAQPDRSDHEMVAGMMFASGMAAVTSALQACTQPGDTIIVQEAIYSATHVYLAQIAPRHQIEVVWVKDPSPENWSRAFEQHPTARLAYVETPSNPTMAVTDIERVAEIAHQYGAWVMVDNTFASPWCQRPLSLGADVVVHSTTKYLCGHGLVIGGVVVSRHVDFIKKDLAFVMKIQGANSNPFDAWLTHLGLKTFELRMKAHCDNAMAVARFLDSHPKVGKVHYPGLESHPDHELATQQMFAYGGMLSFELAGGMQAGIKLMESIRVCTLAVSLGNTDTLVEHPASMSHSNVSAEERAKVGLTDGLVRLSVGIENVEDLIRDLDQALAMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZZ1</accession>
    <name>A0A0P6WZZ1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rubredoxin_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_12695</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063391.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000027.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12695"/>
    <dbReference type="EnsemblBacteria" id="KPL75501">
        <property type="protein sequence ID" value="KPL75501"/>
        <property type="gene ID" value="ADN00_12695"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041166">
        <property type="entry name" value="Rubredoxin_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18073">
        <property type="entry name" value="Rubredoxin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rubredoxin_2" evidence="2">
        <location>
            <begin position="8"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL75501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="64" mass="6898" checksum="2EB94AFD65CC4171" modified="2016-01-20" version="1">MAKTQTCHVCQECGRVSARAMGRCPGCGAWDSLIMVAAIDHSVTTRTMLAAAVTFDVTIRRRGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X0J1</accession>
    <name>A0A0P6X0J1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GBBH-like_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_13740</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063596.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000032.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13740"/>
    <dbReference type="EnsemblBacteria" id="KPL74355">
        <property type="protein sequence ID" value="KPL74355"/>
        <property type="gene ID" value="ADN00_13740"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2020.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010376">
        <property type="entry name" value="GBBH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038492">
        <property type="entry name" value="GBBH-like_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06155">
        <property type="entry name" value="GBBH-like_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GBBH-like_N" evidence="3">
        <location>
            <begin position="11"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF06155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL74355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="116" mass="12995" checksum="D86E902E1C01FC05" modified="2016-01-20" version="1">MINQRETALQIEASKSKRVVEVKWGDGHVSRYGFSLLRAACPCAGCRGGHENMRSEPDEDIFLVELGESDATMLAQIEAVGGYGIRLTWQDGHSDGIFTWHYLRELCSCAECRDEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X120</accession>
    <name>A0A0P6X120_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_11715</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063202.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11715"/>
    <dbReference type="EnsemblBacteria" id="KPL76022">
        <property type="protein sequence ID" value="KPL76022"/>
        <property type="gene ID" value="ADN00_11715"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132762" evidence="1">
        <location>
            <begin position="25"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="238" mass="25888" checksum="6587B27D5623C281" modified="2016-01-20" version="1">MQPRFNRFAILAVLILAACQPVLPEAPLSTPEIWRVQMPASLAWLGARMNVCAQQQAGVALLVDYQPPTTPLLEASDVLVRWGDPDPQDRSDWYKIGEESLAIIIHPQNTTTAISPEQLRQAFTGQVRDWSEISDYSQVLVPVNLPGQDETTLVMGAVSGEAPSITDRTLIAADPAAMIELVAANPGAIGYLPSRWLNESVREISLSGDQPVITTRPLLVKFTSPPTPAQTGWLACLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X2V0</accession>
    <name>A0A0P6X2V0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF2807 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_10895</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063026.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10895"/>
    <dbReference type="EnsemblBacteria" id="KPL77055">
        <property type="protein sequence ID" value="KPL77055"/>
        <property type="gene ID" value="ADN00_10895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021255">
        <property type="entry name" value="DUF2807"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10988">
        <property type="entry name" value="DUF2807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132808" description="DUF2807 domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2807" evidence="2">
        <location>
            <begin position="51"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="249" mass="26157" checksum="6550A1E0675A7002" modified="2016-01-20" version="1">MKKTLLLSLAALMLAMLACSAGGWEININNDGRFVKGSGNITTETRDVSGFNSIEFNGLGDVEIVQGSEEGLTITTDDNLLPLITTEVKGSTLVIGIEKGYNINLPSKMKFTIQVKDLQKLQISGLANVEADDLALQDLYIGISGGSVKLRDLTAKDVRISISGLGNVDLDGEARSVRMDSSGGGSLDAEDLRADSVSISISGVGQASVWAIETLNVEISGGGEVAYYGKPEITRDIDGVGTLNSLGEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5F1</accession>
    <name>A0A0P6X5F1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_07390</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062342.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78280">
        <property type="protein sequence ID" value="KPL78280"/>
        <property type="gene ID" value="ADN00_07390"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009403">
        <property type="term" value="P:toxin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003825">
        <property type="entry name" value="Colicin-V_CvpA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02674">
        <property type="entry name" value="Colicin_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="28"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="63"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="101"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="156"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL78280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="179" mass="19866" checksum="CE271C72FB81C3B8" modified="2016-01-20" version="1">MVGLNVLFWFFIVLFAVIGVMRGWAKELLVLSSAILGLFLITMLETFVPFIKNNLAVSPGPGLFWLRMIIFIVLAFFGYQTPNIPKLASSGRFVRERLQDALLGFFLGAVNGYFLFGSVWYFLQDAGYPYPGVVSDPSGTQFAETAASLMKLLPPVWLGSPAIYFAVAVVFVFILVVFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X6L0</accession>
    <name>A0A0P6X6L0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Multidrug MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_05490</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78701">
        <property type="protein sequence ID" value="KPL78701"/>
        <property type="gene ID" value="ADN00_05490"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1573"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004638">
        <property type="entry name" value="EmrB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00711">
        <property type="entry name" value="efflux_EmrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="15"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="142"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="173"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="204"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="234"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="274"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="307"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="337"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="453"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="18"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL78701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="493" mass="52472" checksum="11B4DF06E9FF74DD" modified="2016-01-20" version="1">MPVTMENQEPNRRELWLALIGVGAGVFMSTLDSSIVNISLPTLVESFQTSFANIQWVVLSYLLVLTSLMLGVARLGDMYNKKRIYLAGMILFAFSSLLCGLAPNIHWLIALRALQGLGAVLMQSLGMAIVTQIFPAKERGRVLGIMGGIVSIGIAVGPPLGGLLISLAGWPSVFWVNVPVGILAAWIVIRYVPDLKPSHPDQRFDFVGALIVMALMSAYALGMTRGQETGFGQPLTLVLLAAAAAGAGLFVWVERRISQPMVDLHLFQNPLFGLNLLMGLLVFIVLAGNFVMPFFLELVKGYPAQQVGWMLMAFPVIMGLVAPAAGALSDRFGSRGISFLGLVILLAGCLAVSTLREETGAWGFILRVLPMGLGFGLFQSPNNSAIMGSAPRERLGVASGLLSLSRTLGQTSGVPLMGALFTAQVHAAGNLPANLDVTEVAPAFLVAGFDGTYRISAVLVFAAALLALFTWMLDKKVGIRAASQVQEKSSEIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X6Q5</accession>
    <name>A0A0P6X6Q5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_05715</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062007.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78737">
        <property type="protein sequence ID" value="KPL78737"/>
        <property type="gene ID" value="ADN00_05715"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1619"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="323" mass="35771" checksum="617FA6F2165A573F" modified="2016-01-20" version="1">MPFPQFDRSRLKLKPLSERIHDLTLDVMMQPTDPAPSFENPDLPTIADRILRAREAGSAIIVMMGAHVLRKGNALLLIDMMKRGLISHIALNGAGVIHDFEFALIGATTESVPRYISEGQFGLWTETGYINDAMVAGQRDQLGLGEAAGRMIEEGNFPYKEYSILAAAYKLQVPITVHVGIGQDIIHEHPNLNGAALGDTSYRDFLIFAESVRRLEGGVLLNIGTSVMGPEVYLKALSMARNVAKQEGKSVCHFTTAVFDLIDLGPNYHNEAPKTNAAYYFRPYKTILVRTVQDGGESFYIQGDHRVTVPSLYHQLISKLEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X6R5</accession>
    <name>A0A0P6X6R5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7 10">Phosphoglycerate kinase</fullName>
            <ecNumber evidence="2 7 10">2.7.2.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 11" type="primary">pgk</name>
        <name evidence="11" type="ORF">ADN00_11635</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7 10">
            <text>(2R)-3-phosphoglycerate + ATP = (2R)-3-phospho-glyceroyl phosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:14801"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57604"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7 10">Belongs to the phosphoglycerate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.3" evidence="2 7 10"/>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063187.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11635"/>
    <dbReference type="EnsemblBacteria" id="KPL76008">
        <property type="protein sequence ID" value="KPL76008"/>
        <property type="gene ID" value="ADN00_11635"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3802"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004618">
        <property type="term" value="F:phosphoglycerate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00318">
        <property type="entry name" value="Phosphoglycerate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1260">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00145">
        <property type="entry name" value="Phosphoglyc_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001576">
        <property type="entry name" value="Phosphoglycerate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015911">
        <property type="entry name" value="Phosphoglycerate_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015824">
        <property type="entry name" value="Phosphoglycerate_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036043">
        <property type="entry name" value="Phosphoglycerate_kinase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11406">
        <property type="entry name" value="PTHR11406"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00162">
        <property type="entry name" value="PGK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000724">
        <property type="entry name" value="Pgk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00477">
        <property type="entry name" value="PHGLYCKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53748">
        <property type="entry name" value="SSF53748"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00111">
        <property type="entry name" value="PGLYCERATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="5 7 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 10" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="7 8">
        <location>
            <begin position="22"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7 8">
        <location>
            <begin position="60"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <position position="152"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="321"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <begin position="347"/>
            <end position="350"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000724-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000724-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL76008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="391" mass="41001" checksum="56CBB68E17CC06B8" modified="2016-01-20" version="1">MFNKKTVKDIDVKGKKVLVRVDFNVPLKEGVVKDDTRIQAALPTLNYLLDEGAALILCSHLGRPKGSPMPEYSMKPVAEYLGKVMGKTVKFAEDTVGPAAEAAAAALKPGEVLVLENTRFEAGETKNDAGMSKKLASFADVFVNDAFGSAHRAHASTVGVADYIPAVAGFLMEKEIRYLGQAIANPDRPFVAILGGAKISDKIGVIKNLLQIADQVLIGGGMANTFFKAQGYPVADSLVEDEALETARELLAGGGQKLRLPVDVVIANAFDNDAETKVTQMGPVPDGWRILDVGPETVENYSKVIMSAGTVVWNGPMGVFEMPNFAKGTFGVAKAVAESKSVSIVGGGDSVAAINQSGLSDKITHISTGGGASLEMLEGIVLPGLAALADK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X6U8</accession>
    <name>A0A0P6X6U8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_11865</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063230.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76045">
        <property type="protein sequence ID" value="KPL76045"/>
        <property type="gene ID" value="ADN00_11865"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="174"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="308" mass="35138" checksum="E2D1A3466FB8F594" modified="2016-01-20" version="1">MMGSDDPAGFEEEGLSAHRLPRFWNPRTKTYTVRQATPLDEDDLSILLSVGFYVHRHLDWRSASHWLSHQPFYVLEEDGFIQAALACPPDLPGMAWVRLYATNSPFDARQAWEALFPPVLEALQAEKGFTLAALSLHEWFSSLLLHTGFQHHHNIIVLEWTRRALHPTALPPHVSIQPMTEEDLQTVCEVDHRAFDRLWRISADEIAHAYLQSAYASVLKCHSQIIAYQISTRTGSHAHLARLAVLPEFQHQGLATRMLEDLLTEFTRRRVRTISVNTQHTNHASIALYKKAGFVLTGESFPVYVYPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X6V5</accession>
    <name>A0A0P6X6V5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PTS sugar transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_08705</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000022">
        <property type="protein sequence ID" value="KPL77664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062606.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000022.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08705"/>
    <dbReference type="EnsemblBacteria" id="KPL77664">
        <property type="protein sequence ID" value="KPL77664"/>
        <property type="gene ID" value="ADN00_08705"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1457"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="202"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="273"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="305"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="346"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="386"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="422"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="448"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="487"/>
            <end position="507"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="518" mass="52682" checksum="A73D64EBD8C83E45" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X784</accession>
    <name>A0A0P6X784_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5 family acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_17925</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000043">
        <property type="protein sequence ID" value="KPL70918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064423.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000043.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17925"/>
    <dbReference type="EnsemblBacteria" id="KPL70918">
        <property type="protein sequence ID" value="KPL70918"/>
        <property type="gene ID" value="ADN00_17925"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2167"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="9"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="174" mass="19371" checksum="44ED3B81745DE50F" modified="2016-01-20" version="1">MPILETERLSLRALTPEDAPFILELFNDPEWLKYIGDRGIRTLQDAANYILNGPIKMRAQHGVALHLVELKGQNTPIGMCGLIKRDTLEDIDLGYAFLPAYRGQGYAYEISRAVLAYGQETFGLQRVVAIIDPRNQRSAHLLEKLGFAYESTFPLGGDPNLVVALYAIALTPLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7D1</accession>
    <name>A0A0P6X7D1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">6-phosphogluconate dehydrogenase, decarboxylating</fullName>
            <ecNumber evidence="4 8">1.1.1.44</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ADN00_03410</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the oxidative decarboxylation of 6-phosphogluconate to ribulose 5-phosphate and CO(2), with concomitant reduction of NADP to NADPH.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 8">
            <text>6-phospho-D-gluconate + NADP(+) = CO2 + D-ribulose 5-phosphate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:10116"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58121"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58759"/>
            <dbReference type="EC" id="1.1.1.44"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 8">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 3/3.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 8">Belongs to the 6-phosphogluconate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.44" evidence="4 8"/>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061560.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03410"/>
    <dbReference type="EnsemblBacteria" id="KPL78957">
        <property type="protein sequence ID" value="KPL78957"/>
        <property type="gene ID" value="ADN00_03410"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.32"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004616">
        <property type="term" value="F:phosphogluconate dehydrogenase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019521">
        <property type="term" value="P:D-gluconate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016054">
        <property type="term" value="P:organic acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006114">
        <property type="entry name" value="6PGDH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006113">
        <property type="entry name" value="6PGDH_Gnd/GntZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006115">
        <property type="entry name" value="6PGDH_NADP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006184">
        <property type="entry name" value="6PGdom_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006183">
        <property type="entry name" value="Pgluconate_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11811">
        <property type="entry name" value="PTHR11811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00393">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03446">
        <property type="entry name" value="NAD_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000109">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00076">
        <property type="entry name" value="6PGDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01350">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00873">
        <property type="entry name" value="gnd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00461">
        <property type="entry name" value="6PGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0311">Gluconate utilization</keyword>
    <keyword evidence="4 8" id="KW-0521">NADP</keyword>
    <keyword evidence="4 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 8" id="KW-0570">Pentose shunt</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6PGD" evidence="9">
        <location>
            <begin position="179"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="129"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="186"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="183"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="190"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="10"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="33"/>
            <end position="35"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="75"/>
            <end position="77"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="103"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="261"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="288"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="446"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="452"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR000109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000109-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000109-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000109-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM01350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL78957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="468" mass="51762" checksum="7F00A85F3FD564CA" modified="2016-01-20" version="1">MKKCDIGLIGLAVMGQNLVLNMERNGYRVGVYNRTTETTMRFMEGPAAGKQIAAAKSIEELFNLLDRPRKVMVMVKAGNPVDAVIEQLLPFLDVGDLVIDGGNSYYKDTERRARQLMEKGIHYLGAGISGGEEGALWGPSIMPGGQAEAYQMVEGIFEAIAARVDGEPCVTYIGPRGSGHYVKMVHNGIEYGDMQLIAEAYDLLHRGAGLNATELHEVFRNWNHGLLESFLIEITAQIFKRVDEKTGQPLVELIMDEAGQKGTGKWTSQEAFDLGVPVPTINSAVSARILSAYKAERVQAAQVLRGPEISPLADRKLFIQQVRDALYTAKISSYAQGFAMLRAASEEFNYDLPFEKIAKIWRGGCIIRARFLNDVSDAFRQGGDLRNLLLAPFFRDAVQTHQGALREVVRQAAAWGIPAPGFSASLAYLDGYRSERLPANLIQAQRDLFGAHTYKRVDEEGIFHSDWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X8A7</accession>
    <name>A0A0P6X8A7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_07625</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062383.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07625"/>
    <dbReference type="EnsemblBacteria" id="KPL78313">
        <property type="protein sequence ID" value="KPL78313"/>
        <property type="gene ID" value="ADN00_07625"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="48"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="192"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="226"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="260"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="414" mass="45530" checksum="6301F87766452E87" modified="2016-01-20" version="1">MTRRRSRSNPLRLFILIVLVGGALYVNQVVVPATPPLFVPTPTPTRSPESYITDADALLEEGKISQAITAYEKAIQANPKNPAVYITTARLQVYNGMYDEAIANAENALLLNANNSIAHALRGWALGFKGEYLEAEAAIKTALEIDPNNAAAYAYRAEILARQWEAGGGLLGTLDNAIEASREAERLGPNQLETHRARGIILELTANYEDASRQFESAIAINPNIADLHLALGRNYRTMELYDRAVEEFNRALALNPKDPLPNTYISRTYATVGEYAKAIQYAEQAIKANPSDPYLYGNLGQMYYKNVQYKDALIPLRLSVRGGTTAEGVEIKGLPLDYGRVAEYYYTYGLTLAQMGECGEALPLSQLLQQAVPNDEYAMYNAQEIINICSKVAEEAPRNPQSTTPEPSATPES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9U7</accession>
    <name>A0A0P6X9U7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_11065</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063074.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76505">
        <property type="protein sequence ID" value="KPL76505"/>
        <property type="gene ID" value="ADN00_11065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="180"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="411" mass="46822" checksum="9221F2310974477D" modified="2016-01-20" version="1">MPETDPQAYISLDCPRCGAPLPEFAEEIVCQYCGARLIFKHARTAPPRPAPARPADPQSLTLVPLTYVEPRTQLDAFTISLPPGWQFEGGITWQNKASAPALLGFRIFNPGGIEQMECFPNQYFGWSTNPMFQMQIPLGGDFYQSEFRPPLSAADFLQQNLIPRQRSKPGMRVLSAQPDPRLAQKTQSRLTPSTPQQQFSVDAARVQIEYQENGLTLREELLANIVYMRVIAGGLFGSVESLFWYTDGLIAWRVRAADFELLHPIFDRVLDSYQPNPQFIAAVQQISQQMTNGVVQQIRNFGQAALRIGRQLSQMNEMQWQSYWDRQHHQEQMWDSWHANQARVDQVHQDYTQAIRGTDEYFDPNAGRTVELPSGYQQVWSNPLGEYIFSDDSLYNPNQESNGSWTLINPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9V6</accession>
    <name>A0A0P6X9V6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_11120</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063085.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11120"/>
    <dbReference type="EnsemblBacteria" id="KPL76515">
        <property type="protein sequence ID" value="KPL76515"/>
        <property type="gene ID" value="ADN00_11120"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.920"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007380">
        <property type="entry name" value="DUF438"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012312">
        <property type="entry name" value="Hemerythrin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04282">
        <property type="entry name" value="DUF438"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01814">
        <property type="entry name" value="Hemerythrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF438" evidence="2">
        <location>
            <begin position="15"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="Hemerythrin" evidence="1">
        <location>
            <begin position="91"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL76515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="420" mass="47878" checksum="B00F34FBC382F630" modified="2016-01-20" version="1">MSEYINNVTRRKELLKDILKGLHQGLPVEVVRQRFAELVKIADSGEIAEVEQMLISEGLPVEEVQRLCDLHVAVVRDALDQQQSPDTVPGHPVFTFRAENQVADRLLRALRKTVEEYAADPAESRRKAVEAALAQVREFEKHYLRKENLLFSLLERYGFTGPSQVMWGIHDQIRADWKKMTTLIEQGAVANSPELAQLMMETFEAFETPMKEMFYKEEKILFPAALERLKEEEWAAIRNQEGELGYFFVQPGTQWKPAYQIILEEETRAAQAKAAVPSAPAAAAPAGLIGLDTGLLSAEQINLLLTNLPVDVTFVDEKDEVRFFSQTKERIFERQAAIIGRKVQFCHPPKSLDAVQRILDDFRAGKRDVAEFWIQMMGKFIHIRYYAMRDAQGVYKGTLEVSQDVTGIRALEGERRLLDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XA67</accession>
    <name>A0A0P6XA67_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_02360</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000010">
        <property type="protein sequence ID" value="KPL79661.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061355.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000010.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02360"/>
    <dbReference type="EnsemblBacteria" id="KPL79661">
        <property type="protein sequence ID" value="KPL79661"/>
        <property type="gene ID" value="ADN00_02360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ADH_N" evidence="2">
        <location>
            <begin position="25"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="ADH_zinc_N" evidence="1">
        <location>
            <begin position="178"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79661.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="346" mass="37081" checksum="331C41F2E8756A2D" modified="2016-01-20" version="1">MKAAYLVGPQQFEVREVPEPEVPEDGVLLDVKACGVCGSDLRRWREGLPEGRDPYVQGHEFAGVVLAVGPQQKDYKVGDLLAVAADVHCGKCYYCQRGMYNLCENARLVGISAGMPGGLAQKAALSGDILTNGIIHRMPEGMSFEHAALAEPLSSVLAAHHKAETNLSHTVVVLGGGPIGCFHIAVAHARGAKVILSEPSAERRQMAEPFHPEFVIDPFNEDVVARVRELTGGLGADIVVCANPIVATQTQAVEMVRKAGRVILFGGLPKANPMTSLNANRIHYDEIEVVGAFSYHPIFHEQALDVLQRGLIDGDTVITHVFSLDDVDKAFQASASGQALKAIVKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAC2</accession>
    <name>A0A0P6XAC2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_15905</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064027.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15905"/>
    <dbReference type="EnsemblBacteria" id="KPL72107">
        <property type="protein sequence ID" value="KPL72107"/>
        <property type="gene ID" value="ADN00_15905"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3614"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="3"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="126"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="126"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL72107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="227" mass="25416" checksum="5DA5939864ABF2EE" modified="2016-01-20" version="1">MTTILMIEDEPALVRILRSYLEQAAFQVETAGRGDTGLDMWRAIQPDLVLLDLNLPGMDGLDVAREIRKQANTPIIMVTARVEEIDRLIGLELGADDYITKPYSPREVVARVKAVLRRASSIQKRANFLQTGDLSIDLDAHLVSRNGEIIDLTPTEFNLLVTLAGYPGRVFSRLQLLEATQGTAYEGYERTVDAHIKNLRAKLEINPKEPQYVETVFGVGYRFSRSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAP6</accession>
    <name>A0A0P6XAP6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_15565</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063950.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15565"/>
    <dbReference type="EnsemblBacteria" id="KPL72235">
        <property type="protein sequence ID" value="KPL72235"/>
        <property type="gene ID" value="ADN00_15565"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007624">
        <property type="entry name" value="RNA_pol_sigma70_r3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04539">
        <property type="entry name" value="Sigma70_r3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="6">
        <location>
            <begin position="32"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r3" evidence="5">
        <location>
            <begin position="115"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4" evidence="7">
        <location>
            <begin position="205"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL72235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="264" mass="30411" checksum="2ADC196A1F924081" modified="2016-01-20" version="1">MKTSNGCLLDEDITRRLLKQAQSGDQSAVETLLQRNQRFIQSIARKYYHPERMNDLELDDLVQLGSIGFCMAIQRWDDSKENRFSTYAYYWVRAYIRREALKSDAGTSVSYRFSEKLMEFRRAYSKVFAEQGREPTVRELVDATGMPEDEVGLATLSIQSGYSHSPRLSDDGEELDEGETIPSEVNVESDAIHSALLSEVELIVAQMPKKYQTVMAHRFSLWGQPEMTQRELSKKMGVAFQRVQKIEKKALDHLRQQLTNSRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAQ8</accession>
    <name>A0A0P6XAQ8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_15665</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063970.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72253">
        <property type="protein sequence ID" value="KPL72253"/>
        <property type="gene ID" value="ADN00_15665"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="210" mass="22359" checksum="A2D3556C37BAF68A" modified="2016-01-20" version="1">MAIDVALLDTRSSGTTGTWSSTVNIPADKSPACLILFLFNKGGLGGVNYVRIGGVTPDTIKSYSGSNVGFGVFARKDLAPGDYLVEVNASGENRGIILGVWETIGWNTNPSSQYTSVLPSPGNLSFNPTLASGQLFLEFYKQNSGTDNARTAGQTLLSHLTGTGYEGGAAYKKSGGPYTWTTYVYDQYLFGLEFMPLGRLFFIPPAPIGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAR7</accession>
    <name>A0A0P6XAR7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_09375</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062730.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09375"/>
    <dbReference type="EnsemblBacteria" id="KPL77325">
        <property type="protein sequence ID" value="KPL77325"/>
        <property type="gene ID" value="ADN00_09375"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4109"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="287"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="339"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="371"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="21"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="316"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL77325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="410" mass="44077" checksum="22DFCEBC984031E9" modified="2016-01-20" version="1">MILKEVFRASWKSILSNKSRSLLTMLGVIIGVAAVIVMMAISAGTEATISDAITGLGSNLLFVRSSMMRGGPGEPGTNRQNLVYEDVTAISEQISGVAGVTVDQTSSVTIKFGNNALEDIALVGTTPDYTVVRDVEVDEGRFFTENEVDRTQKVVVLGSAVAEELFGSEDPIGQLVTVDDVRLTVVGVMKEKGLVSGVNFDEQIYTPISVVFSKFVPNQFARIFGNDIRMIYVSVEDGANMEEVSDQILRLLAKRKEVSLDEATFTIQSQEDIIETQESTTESFRNLLAWVAGVSLIVGGIGIMNIMLVSVTERTREIGLRQAIGATPGDIQIQFLSEALMLSLIGGLLGVLAGVGGSILFGQFGGMRTVIVPYSIALSFTSAALVGIFFGYMPARRASQLDPIEALRHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBP6</accession>
    <name>A0A0P6XBP6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_08785</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000022">
        <property type="protein sequence ID" value="KPL77691.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08785"/>
    <dbReference type="EnsemblBacteria" id="KPL77691">
        <property type="protein sequence ID" value="KPL77691"/>
        <property type="gene ID" value="ADN00_08785"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="148"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="192"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="243"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="83"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL77691.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="284" mass="31102" checksum="ED676EBFC510F975" modified="2016-01-20" version="1">MSLPWQGKRKVEPISPEKNRLTMRDLAGKHSPWVILLSIGMFIGAWQLITTWRDYPAFILPGPRLVAERFVRALADGSLLRHSGITLLEVLLGLLAGSVSATALGYLLAKSRLLERLLSPYLVASQAIPIVAIAPLLVIWFGPGMASKVLICALIVFFPVLVNTIVGLRAVPDNLRDLMRSMRATRRQVLRYLEIPAALPIFLGGLRIGATLSVIGAVVGEFVGSDRGLGFLINVGRGQYDTALVFVAIFTLVAMALALYGLVVSLERRLLAWRNASNHFRETL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBR3</accession>
    <name>A0A0P6XBR3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_02285</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000010">
        <property type="protein sequence ID" value="KPL79648.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79648">
        <property type="protein sequence ID" value="KPL79648"/>
        <property type="gene ID" value="ADN00_02285"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79648.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="126" mass="13918" checksum="B0D64BC633B98A50" modified="2016-01-20" version="1">MRDFSLVFGGIPADSHWTLAAISVAKGPKEFMPLGEQNNGLQEKYLDSDNPSSNQSHHYSGLLFLGYFFGSNLSRPINTLREIDTSNQGDILLGEAAISDAIDFRSDFESYEDLIDKIRALAVDSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XC03</accession>
    <name>A0A0P6XC03_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_09340</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062724.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77319">
        <property type="protein sequence ID" value="KPL77319"/>
        <property type="gene ID" value="ADN00_09340"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL77319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="73" mass="8261" checksum="ABDF5C1C30CC2568" modified="2016-01-20" version="1">MENRFEFKSSTADDGTIGDCMLGQEEVAAIEEALRKVCPFGEVRLVVERGRLRWLVVQQSLDVLKLVRHAKAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDL6</accession>
    <name>A0A0P6XDL6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">7,8-dihydroneopterin aldolase</fullName>
            <ecNumber evidence="1">4.1.2.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_00620</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the conversion of 7,8-dihydroneopterin to 6-hydroxymethyl-7,8-dihydropterin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>7,8-dihydroneopterin = 6-hydroxymethyl-7,8-dihydropterin + glycolaldehyde</text>
            <dbReference type="Rhea" id="RHEA:10540"/>
            <dbReference type="ChEBI" id="CHEBI:17001"/>
            <dbReference type="ChEBI" id="CHEBI:17071"/>
            <dbReference type="ChEBI" id="CHEBI:44841"/>
            <dbReference type="EC" id="4.1.2.25"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 7,8-dihydroneopterin triphosphate: step 3/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DHNA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.25" evidence="1"/>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00620"/>
    <dbReference type="EnsemblBacteria" id="KPL81069">
        <property type="protein sequence ID" value="KPL81069"/>
        <property type="gene ID" value="ADN00_00620"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00154"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004150">
        <property type="term" value="F:dihydroneopterin aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00534">
        <property type="entry name" value="DHNA_DHNTPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006156">
        <property type="entry name" value="Dihydroneopterin_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006157">
        <property type="entry name" value="FolB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42844">
        <property type="entry name" value="PTHR42844"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02152">
        <property type="entry name" value="FolB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00905">
        <property type="entry name" value="FolB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00525">
        <property type="entry name" value="folB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00526">
        <property type="entry name" value="folB_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="1" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FolB" evidence="2">
        <location>
            <begin position="6"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU362079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL81069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="121" mass="13648" checksum="356EC927A7E40BD0" modified="2016-01-20" version="1">MMSDQIQIKDLLLRTIIGINEDERINPQDILINLTLFTNTRAAGESDDIADAVNYRSITKQVIALVETSRFYLVEKMAAEIAKVCLENPQVEKVRVSVEKPGALRFTRSVGVTIERGRNEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XEQ9</accession>
    <name>A0A0P6XEQ9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_05285</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061929.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78669">
        <property type="protein sequence ID" value="KPL78669"/>
        <property type="gene ID" value="ADN00_05285"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="88" mass="10317" checksum="E17C04A2FCA93F2E" modified="2016-01-20" version="1">MGRTLPTITDAFYREQESFNRFRRALRRSDQKVLDDLFASARLHLAAASYAADALPMETFLLAMLLEQHKEVMRLRAQVEEFSRPRDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XEY8</accession>
    <name>A0A0P6XEY8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Electron transfer flavoprotein subunit beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062023.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05800"/>
    <dbReference type="EnsemblBacteria" id="KPL78751">
        <property type="protein sequence ID" value="KPL78751"/>
        <property type="gene ID" value="ADN00_05800"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1636"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01714">
        <property type="entry name" value="ETF_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014730">
        <property type="entry name" value="ETF_a/b_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012255">
        <property type="entry name" value="ETF_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033948">
        <property type="entry name" value="ETF_beta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21294">
        <property type="entry name" value="PTHR21294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01012">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000090">
        <property type="entry name" value="Beta-ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00893">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ETF" evidence="1">
        <location>
            <begin position="22"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="265" mass="29284" checksum="5333E7936A7D3B3A" modified="2016-01-20" version="1">MNIIVCIKQVPSTSEVNIDEKTGSLIRSGIDAKMNPYDLFAIETALQIKQSREAKIIALTMGPPQAEEIIREAFMMGADEGYVLSDRRLAGADVLATAYALSQCVLKIGLPDLIICGKQTTDGDTAQVGPEIAEFLDIPHITNVFRIEDLNEQTMTVSADLPGTVETAAVSLPALISVEKDIYQPRLPSYRLKRSTGQKKVVFYRLDDLPDSDERHYGLAGSPTRVVRVFPPEKDQANEFWEGSPDELAKKLAQSLIDWKFVEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XFS6</accession>
    <name>A0A0P6XFS6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glycosyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_03860</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061648.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03860"/>
    <dbReference type="EnsemblBacteria" id="KPL79035">
        <property type="protein sequence ID" value="KPL79035"/>
        <property type="gene ID" value="ADN00_03860"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.126"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033432">
        <property type="entry name" value="GH36_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037018">
        <property type="entry name" value="Glyco_hydro_65_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010383">
        <property type="entry name" value="Glyco_hydrolase_94"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17167">
        <property type="entry name" value="Glyco_hydro_36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06165">
        <property type="entry name" value="Glyco_transf_36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_transf_36" evidence="2">
        <location>
            <begin position="21"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_36" evidence="3">
        <location>
            <begin position="304"/>
            <end position="728"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL79035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="803" mass="89874" checksum="13CDC1F7B7EBDF4C" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XFU2</accession>
    <name>A0A0P6XFU2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_04000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061672.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04000"/>
    <dbReference type="EnsemblBacteria" id="KPL79053">
        <property type="protein sequence ID" value="KPL79053"/>
        <property type="gene ID" value="ADN00_04000"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004582">
        <property type="term" value="F:dolichyl-phosphate beta-D-mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06442">
        <property type="entry name" value="DPM1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039528">
        <property type="entry name" value="DPM1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43398">
        <property type="entry name" value="PTHR43398"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="14"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="250" mass="28200" checksum="25DCB7EEC0C15C10" modified="2016-01-20" version="1">MLAVVQTGWKLKTTIVIPTYNEAENLPKLAAALFALPLPELSLLVVDDNSPDGTGQIAEELCQQYPGRVSVMHRAGKQGLGTAYIQGFHKAIEQGAEAIGQMDADFSHPVEKVLELVKTLETCDVVLGSRYVPGGSLDERWPFWRKALSGFGNFYARTILGMSLRDVTGGFKLWRRETLQGMPLERVRSNGYIFQVEMSYVATKLGYKFKEIPIYFADRRWGQSKMSFRIQVEAALRVWQLAKMYRDLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGC7</accession>
    <name>A0A0P6XGC7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">3-isopropylmalate dehydratase small subunit</fullName>
            <ecNumber evidence="10">4.2.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Alpha-IPM isomerase</fullName>
            <shortName evidence="10">IPMI</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Isopropylmalate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">leuD</name>
        <name evidence="12" type="ORF">ADN00_19065</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 10">Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate</text>
            <dbReference type="Rhea" id="RHEA:32287"/>
            <dbReference type="ChEBI" id="CHEBI:1178"/>
            <dbReference type="ChEBI" id="CHEBI:35121"/>
            <dbReference type="EC" id="4.2.1.33"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 2/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 10">Heterodimer of LeuC and LeuD.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 10">Belongs to the LeuD family. LeuD type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.33" evidence="10"/>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064629.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_19065"/>
    <dbReference type="EnsemblBacteria" id="KPL70136">
        <property type="protein sequence ID" value="KPL70136"/>
        <property type="gene ID" value="ADN00_19065"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3126"/>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00071"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009316">
        <property type="term" value="C:3-isopropylmalate dehydratase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003861">
        <property type="term" value="F:3-isopropylmalate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01577">
        <property type="entry name" value="IPMI_Swivel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01031">
        <property type="entry name" value="LeuD_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004431">
        <property type="entry name" value="3-IsopropMal_deHydase_ssu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000573">
        <property type="entry name" value="AconitaseA/IPMdHydase_ssu_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033940">
        <property type="entry name" value="IPMI_Swivel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00694">
        <property type="entry name" value="Aconitase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00171">
        <property type="entry name" value="leuD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9 10" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="6 10" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="8 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aconitase_C" evidence="11">
        <location>
            <begin position="1"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KPL70136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="197" mass="21241" checksum="08F9B18D27F1AEAC" modified="2016-01-20" version="1">MQAFTTLTSLVAPLLVNDIDTDQIIPARFLKGIDKAGLGSKLFSDWRYTPGGEPDPNFILNQPPFDSAQILLAGDNFGCGSSREHAPWALTDFGIRAIISTSFADIFFNNAQKNGLLPVIVPPSVHQALVNSLAADPLATVSIDLAAQTVTLPGGVTQSFDIHPFSKHCLLHGMDDLDYVLSFSEAINQYEAAHQAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGE2</accession>
    <name>A0A0P6XGE2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05025</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061859.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79208">
        <property type="protein sequence ID" value="KPL79208"/>
        <property type="gene ID" value="ADN00_05025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133047" evidence="1">
        <location>
            <begin position="30"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="151" mass="15995" checksum="F178B50E8343B529" modified="2016-01-20" version="1">MNHVTKPWPIIFTICLALLFTACAAPAQAQPLSQPALVIRSSTTALGAEGDQQQIGVLSYTFVLENTSQQDILLLAFTPQLNPAYAARLLGKLQAVPVGLGLSGGETVELGGQLRFDFSGLSKQDIEALGHPLAGWLIQSESFIPQPGSQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XH41</accession>
    <name>A0A0P6XH41_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_04420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061744.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79111">
        <property type="protein sequence ID" value="KPL79111"/>
        <property type="gene ID" value="ADN00_04420"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="168"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="310" mass="35454" checksum="7D0522274E342018" modified="2016-01-20" version="1">MTDSTIHSRPFQDEQDFWHIRELSIQSYAFTGLGFNWDFRRWDGSRFHNPTGELNPNWPKTIQLWITSGDHLAGAANLDGPGWFSLQINPVYRAEIEESMLDWVEEHGPAPDNETGQPTLQTEVFDHDCVRRRLLEARGFKMLDDGGVIRRMYLVAPSIPEAPLAEGYTLAEVNPHDLHDCQRMADLLNAAFNRTKHNALEFQQFGLHAPSYRQDLHLVAVAPDGSYAAHVAAIFDSYNHRAIYEPVCTHPDHRRKNLAQSLMYEAMRRVKALGAIQITVDTGDMIPANKLYDSMGFTEAYKSHVWKKTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XHA8</accession>
    <name>A0A0P6XHA8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063540.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000031.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74840">
        <property type="protein sequence ID" value="KPL74840"/>
        <property type="gene ID" value="ADN00_13460"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="139" mass="15433" checksum="7A1CAE7A34B0E88A" modified="2016-01-20" version="1">MIAKIVIISFIILETSNVLALYFAPGSKRANAVGVFSAWEESKQYPEIHDFIQYLVNWVAGAKLIFLLLLGVIALFGDLNLQRLSLLALAAATLSFYGRLFPLIRKMDRNGQVDPKNYSTVLGVMIFILIVVFLLAALV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XHC8</accession>
    <name>A0A0P6XHC8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4173 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_05050</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061864.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05050"/>
    <dbReference type="EnsemblBacteria" id="KPL79212">
        <property type="protein sequence ID" value="KPL79212"/>
        <property type="gene ID" value="ADN00_05050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.380"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025231">
        <property type="entry name" value="DUF4173"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13777">
        <property type="entry name" value="DUF4173"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="202"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="242"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="291"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="324"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="364"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="387"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4173" evidence="2">
        <location>
            <begin position="254"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="535" mass="59234" checksum="A73C108030457F00" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XHI8</accession>
    <name>A0A0P6XHI8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Methylmalonyl-CoA mutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13885</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063622.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000032.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13885"/>
    <dbReference type="EnsemblBacteria" id="KPL74377">
        <property type="protein sequence ID" value="KPL74377"/>
        <property type="gene ID" value="ADN00_13885"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1354"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004494">
        <property type="term" value="F:methylmalonyl-CoA mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016176">
        <property type="entry name" value="Cbl-dep_enz_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006099">
        <property type="entry name" value="MeMalonylCoA_mutase_a/b_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006098">
        <property type="entry name" value="MMCoA_mutase_a_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01642">
        <property type="entry name" value="MM_CoA_mutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51703">
        <property type="entry name" value="SSF51703"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00641">
        <property type="entry name" value="acid_CoA_mut_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="METMALONYL_COA_MUTASE" evidence="1">
        <location>
            <begin position="31"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="549" mass="61167" checksum="503323376E4E0DD3" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XHP8</accession>
    <name>A0A0P6XHP8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Bac_transf domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_03210</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial sugar transferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000014">
        <property type="protein sequence ID" value="KPL79349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061529.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000014.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03210"/>
    <dbReference type="EnsemblBacteria" id="KPL79349">
        <property type="protein sequence ID" value="KPL79349"/>
        <property type="gene ID" value="ADN00_03210"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2053"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003362">
        <property type="entry name" value="Bact_transf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02397">
        <property type="entry name" value="Bac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="domain" description="Bac_transf" evidence="3">
        <location>
            <begin position="8"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL79349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="206" mass="24029" checksum="EC150CF10880BCA1" modified="2016-01-20" version="1">MRAISPAKRAFDLLVSSLALLLLSPLMLVVALLILMVDGRPVFFRQPRPGYKGRIFTLYKFRTMRHAFDRRGQPLPDAQRVSRLGKILRLTSIDELPELFNILRGEMSLVGPRPLLVEYLERYSAEQMRRHDVLPGLTGWAQINGRNAISWQEKFRLDVWYVDHWSFWLDLKIIFLTFWKVIRREGISQPGQATTEYFTGNPPEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XJ02</accession>
    <name>A0A0P6XJ02_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_01810</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000006">
        <property type="protein sequence ID" value="KPL80123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061253.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000006.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80123">
        <property type="protein sequence ID" value="KPL80123"/>
        <property type="gene ID" value="ADN00_01810"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032688">
        <property type="entry name" value="ABC2_membrane_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12679">
        <property type="entry name" value="ABC2_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="98"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="142"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="177"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="215"/>
            <end position="236"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL80123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="248" mass="27132" checksum="3DE87BA35521305F" modified="2016-01-20" version="1">MMTDVLVVMSKEIREFLLQRGESRRSGWVNILVVLGLLGVYMPVMSKAEWLTNPMVSLSWSWLPIFLTSAMITDSFAGERERHTLETLLASRLSDQAILFGKILAAVVYACGLTLASLLLGAVTVNVITWGEGLRFYALMPFVGAMLLMVLAALLMSSVGVLVSLRSATVRSAYQKLSLAIMALWVVPMLVLQFLPKGTIAGWMDSLAGMQINLGWVMLGVGLVLAVIDAVLLAVARARFQRSRLILD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XJT5</accession>
    <name>A0A0P6XJT5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_12070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063269.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76075">
        <property type="protein sequence ID" value="KPL76075"/>
        <property type="gene ID" value="ADN00_12070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="8"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="195" mass="21739" checksum="F5CB9D6E61DC0D7D" modified="2016-01-20" version="1">MSTSEVGLEILPLTPDRWEDLEKLFGPRGADGGCWCMFFRLPHRQFTEQQGEANRAAFKQIVEEGTEPGLIAYAGGKPVGWVAVAPRAEYGRLARSRVLRPLDQEDVWSVVCFFVDKAYRKQGISTCLLKAAVGFAAQHGAKIVEGYPVDLSDRTYPDAFAYHGTASSFLEAGFVEVARRSPTRPMMRYTISERN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKJ5</accession>
    <name>A0A0P6XKJ5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pyridine nucleotide-disulfide oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_12690</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12690"/>
    <dbReference type="EnsemblBacteria" id="KPL75548">
        <property type="protein sequence ID" value="KPL75548"/>
        <property type="gene ID" value="ADN00_12690"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="3">
        <location>
            <begin position="4"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_dim" evidence="2">
        <location>
            <begin position="329"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL75548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="446" mass="47407" checksum="4544D8B27592B2A2" modified="2016-01-20" version="1">MQTDVLVLGGLSGITAGLSCRRHYPDKKVVLVRKEGTVLIPCGIPYIYGTVGGPQNNVIPDGLLETNNIELVKGEAVSVDREHKLVTLKDGETILYDKLVFATGSLPLVPPIPGVDKKNIYAIKKDFNYLDSVLDEMKSVKDLVIVGGGFIGVEFADECRKGRDINVTVIEALSHCLQMALDDEFCAEAEAKLLETGVKIMTGVKVEAFVGDEAVSGVKLADGTVIKADMVILGIGATPNTELAQKAGLELGFRNAIKVDRYMQTYTDPNVFACGDCAEKQSFFTGRPTGVMLASIATSEARIAGANLYSTVHQNCGAISVFSTIVNGRAFAVAGLTERQARQYGMNIVIGKAEAPDTHPGGMPNSTLIKVKLVFAKETGVLIGGSISGGKSIGEMVNVLSACIMHRMTADDIVKFQMGTHPALTSSPIAYPIVNAACKAVLPIRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XLC0</accession>
    <name>A0A0P6XLC0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_00740</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061036.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00740"/>
    <dbReference type="EnsemblBacteria" id="KPL81086">
        <property type="protein sequence ID" value="KPL81086"/>
        <property type="gene ID" value="ADN00_00740"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL81086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="312" mass="36468" checksum="23D3BB3FC613F175" modified="2016-01-20" version="1">MLRISGLIKLTNSLHEEFFRCSRLEGKEYQAAIQSSRDDILALTTSIHKKLSAYDSPLNQLTSPARQAYLWLAYLVEEDHLEQHCRSLARAARAFQTALPRKQNFDIRFYNCKYTYSIHHNSQSVHATLHEGFIYAPDSVFNEIVKTLKKNASAKNNPVIKAFIATRPFQNCYTQLNPSLKPKKIHIQGAFHDLNASFERVNRKYFNNKLEKPTLTWSARRTYRTMGCYDVTKDILTVSRSLDHQTVSLHTLDFIMYHELLHKYFGTKSVNGRHISHSARFREAEKSFEHFQQAAQELQRISQEEKKRQSRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XLS7</accession>
    <name>A0A0P6XLS7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">dTDP-4-dehydro-6-deoxyglucose aminotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_08930</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the DegT/DnrJ/EryC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062651.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08930"/>
    <dbReference type="EnsemblBacteria" id="KPL77254">
        <property type="protein sequence ID" value="KPL77254"/>
        <property type="gene ID" value="ADN00_08930"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4019"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00616">
        <property type="entry name" value="AHBA_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000653">
        <property type="entry name" value="DegT/StrS_aminotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30244">
        <property type="entry name" value="PTHR30244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01041">
        <property type="entry name" value="DegT_DnrJ_EryC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000390">
        <property type="entry name" value="PLP_StrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="200"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL77254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="403" mass="44854" checksum="6192E178AF887054" modified="2016-01-20" version="1">MKKTIDDLAIFGAPPAFSKSLHVGRPNIGNREKLMQRINYILDSRWLTNDGTFVQEFEQRIAEIVGVKHCIAMCNATIALEIAIRASGMTGEVIVPSMTFVATAHALQWQEITPVFCDIDPVTCNIDPKKIEQMITPRTTGIIGVHLWSRPCDVDALAELAQKHNLKLIYDAAHAFGCSYNGKMIGNFGDAEVFSFHATKFLNSAEGGAVVTNDDELAQKIRWMKNFGFEDVDLVVYIGTNGKMNEFSAAMGLTSLESLDEIIETNRQNYFHYRKELSGIPGVTLAQFNEGEKCNYQYIIVQIDKDVTGISRDEIKDILWSENILARRYFYPGCHRMEPYRSYFPHAGLLLPETERLADRVLALPTGTAVGAAEISEVANIIRLAIANSKQIGEKLGNRPAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XLV2</accession>
    <name>A0A0P6XLV2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glucosamine--fructose-6-phosphate aminotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_09155</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062692.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09155"/>
    <dbReference type="EnsemblBacteria" id="KPL77291">
        <property type="protein sequence ID" value="KPL77291"/>
        <property type="gene ID" value="ADN00_09155"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4065"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901135">
        <property type="term" value="P:carbohydrate derivative metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05008">
        <property type="entry name" value="SIS_GlmS_GlmD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05009">
        <property type="entry name" value="SIS_GlmS_GlmD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035466">
        <property type="entry name" value="GlmS/AgaS_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035490">
        <property type="entry name" value="GlmS/FrlB_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SIS" evidence="2">
        <location>
            <begin position="28"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="2">
        <location>
            <begin position="194"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="345" mass="38346" checksum="28901674BEF87D0F" modified="2016-01-20" version="1">MSLIEEINEQPQVLSRLLSTQFDAIAAIADQIKQWDPNFVFVAARGTSDNAGRYANYLFGAHNQLPLALATPSLFTYYHRPPKLKQALVMGISQSGKSPDIVSVLEEGRRQGCKTMAITNAVQSPLADQADFVIDIMAGPEKAVAATKSYTAELMVIAMLSVCLAGDEQRKAELARVPEWVAKTLELDGYIENFAQRYRYMEQCVVLGRGYNYSTAFEWSLKMKELTYVVAEPYSSADFRHGPIAMVEQGFPVLAVAPNGEVFDTLKELLVHLRKDMQAELVVISDRKDALELAHVPVELPAGIPEWLTPLVSIIPAQLFAFHLTKVKGFDTETPRSIRKVTETH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XNG0</accession>
    <name>A0A0P6XNG0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 13">Dihydrolipoyl dehydrogenase</fullName>
            <ecNumber evidence="3 13">1.8.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">ADN00_14580</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>(R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + NAD(+) = (R)-N(6)-lipoyl-L-lysyl-[protein] + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:15045"/>
            <dbReference type="Rhea" id="RHEA-COMP:10474"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="EC" id="1.8.1.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11 13">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="11 13">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="13">The active site is a redox-active disulfide bond.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.4" evidence="3 13"/>
    <dbReference type="EMBL" id="LGCL01000035">
        <property type="protein sequence ID" value="KPL73565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063764.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000035.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14580"/>
    <dbReference type="EnsemblBacteria" id="KPL73565">
        <property type="protein sequence ID" value="KPL73565"/>
        <property type="gene ID" value="ADN00_14580"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2082"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004148">
        <property type="term" value="F:dihydrolipoyl dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006258">
        <property type="entry name" value="Lipoamide_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012999">
        <property type="entry name" value="Pyr_OxRdtase_I_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01350">
        <property type="entry name" value="lipoamide_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00076">
        <property type="entry name" value="PYRIDINE_REDOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5 11 13" id="KW-0274">FAD</keyword>
    <keyword evidence="4 13" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7 11 13" id="KW-0520">NAD</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 13 16" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9 13" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="15">
        <location>
            <begin position="5"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_dim" evidence="14">
        <location>
            <begin position="347"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="445"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="181"/>
            <end position="188"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="271"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="312"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="12">
        <location>
            <begin position="42"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KPL73565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="466" mass="49648" checksum="6AA8DD40C41278CA" modified="2016-01-20" version="1">MSEQYDVVVLGAGPGGYVSAIRAAQLGLKTAIVEKKWLGGVCLNVGCIPSKALLKNADLAETLRERTKEFGISFENLQLDYSVAVKRSRQVSDRLTKGVGFLMKKNKIDVLMGAGKITAPGTIVVTDEKGAAQEVKTKNIIVATGAQSTVPPVWKIDGEKVLTYTEAILQTKRPASAVIIGAGAIGVEFSTIWNSYGTDVTIVEMLPQILPLEDPEASAELAKAYKKRGIKLLTSTKVESIETTETGVKVKVSGADGEQVLEAEQAMVAIGFRPNSKGFGLEEVGVKLDQRGFVEVDDAMRTNVPGIYAIGDVTGKLLLAHVASAMGMVAAESIAGAHTVKLDYRMMPRAVYSHPQVASFGYTEQQAKDAGYEIKVGRFNFIANGKSLGLGESAGWAKIISDAKYGEILGAVLVGPDVSELLPELVLAQRMELTAEEIARTVHAHPTLSEVVMEAAHGVEGLPIHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XNW9</accession>
    <name>A0A0P6XNW9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_10175</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062893.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76947">
        <property type="protein sequence ID" value="KPL76947"/>
        <property type="gene ID" value="ADN00_10175"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13187">
        <property type="entry name" value="Fer4_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="193"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="223"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL76947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="290" mass="32390" checksum="4A998CB1DA871450" modified="2016-01-20" version="1">MNIVLLYLSPNKTTHKVSLALARRLEQDGHSVSLLDAGKPGQRSPIEVDPCLFENADVIGVGSPVFNLRILRPLKQYLRQALPHFSKDVKAFIYITYGGITSGKAFLNAASLLKQHKIPVVGGFKVRAPHFYSSESYPDAAALQTIDQFCAQVSANLFRAMPWPQVEQAFGYQGWKVRLIYPFAQIVGELRRLPIHFDTQRCLRCQRCIRECPANALKMDDYPVLDKHKCVHCYHCATICPQQAILCPTYKVEGMAKVNVKLLGHEQPQNAIYLLPPAGAVGSIGQRGYN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XP99</accession>
    <name>A0A0P6XP99_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Ribonuclease H</fullName>
            <shortName evidence="5">RNase H</shortName>
            <ecNumber evidence="4 5">3.1.26.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rnhA</name>
        <name evidence="8" type="ORF">ADN00_10485</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Endonuclease that specifically degrades the RNA of RNA-DNA hybrids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="5">Binds 1 Mg(2+) ion per subunit. May bind a second metal ion at a regulatory site, or after substrate binding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 5">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the RNase H family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.4" evidence="4 5"/>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10485"/>
    <dbReference type="EnsemblBacteria" id="KPL77075">
        <property type="protein sequence ID" value="KPL77075"/>
        <property type="gene ID" value="ADN00_10485"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2568"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004523">
        <property type="term" value="F:RNA-DNA hybrid ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006401">
        <property type="term" value="P:RNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09278">
        <property type="entry name" value="RNase_HI_prokaryote_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00042">
        <property type="entry name" value="RNase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002156">
        <property type="entry name" value="RNaseH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022892">
        <property type="entry name" value="RNaseHI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00075">
        <property type="entry name" value="RNase_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50879">
        <property type="entry name" value="RNASE_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase H type-1" evidence="7">
        <location>
            <begin position="2"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="146"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="11"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL77075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="170" mass="18773" checksum="D3105B39BD2F28DE" modified="2016-01-20" version="1">MSKPQVIIYTDGGAIGNPGPGGYGAVILQAGQRKELSGGYRLTTNNRMELTAAVEALRVLPVSSQVTLHTDSKYLVDAVTQGWAKRWRANGWKRNKKDKALNPDLWQQLLDLLEKHQVEFVWVKGHAGNRENERCDRLAVQAASGKNLPADAGYRPDDETGGEPRQLNLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XPK2</accession>
    <name>A0A0P6XPK2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_06620</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000017">
        <property type="protein sequence ID" value="KPL78589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062191.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000017.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06620"/>
    <dbReference type="EnsemblBacteria" id="KPL78589">
        <property type="protein sequence ID" value="KPL78589"/>
        <property type="gene ID" value="ADN00_06620"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2832"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001360">
        <property type="entry name" value="Glyco_hydro_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033132">
        <property type="entry name" value="Glyco_hydro_1_N_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10353">
        <property type="entry name" value="PTHR10353"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00232">
        <property type="entry name" value="Glyco_hydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00131">
        <property type="entry name" value="GLHYDRLASE1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00653">
        <property type="entry name" value="GLYCOSYL_HYDROL_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="441" mass="50611" checksum="92D83B1C4E0EAF91" modified="2016-01-20" version="1">MPQARFAFPKGFLWGCATAAHQVEGGNTNNNWYAWENEPGRIIHGHQSGKACDWWSGRWREDFDRAAETGQNAHRLSIEWSRVQPAPDRWDENAIDAYREMIRGLIQRKLTPMVTLHHFTDPLWLTEQGGWESEQAPELFAVYVRKIVEALKDLVSLWITINEPNVYTYGGYLNGGFPPGKNDMNLAFQVLFNLLKGHSLAYKIIHDLQPSALVGIAPNYRSFYPARAWLPLDAAAANLLHASYNDAFPRATRTGTLKFGFKSAELPAALGTMDFVGINYYTRDLVKFALKPAQMFNERFFPPDAALSETGFLANVPDGFREGLRWAEKFGLPIYITENGVEDSKDLLRPRYLVEHIHQVWRIANLNVPIKGYFQWSLVDNFEWERGWTQRFGLWGLDVDTQKRIRRPSVDLYEAICKQNAIHSDVVQRFAPQSFARLFPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XRB3</accession>
    <name>A0A0P6XRB3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_07920</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062450.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07920"/>
    <dbReference type="EnsemblBacteria" id="KPL77806">
        <property type="protein sequence ID" value="KPL77806"/>
        <property type="gene ID" value="ADN00_07920"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.584"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038728">
        <property type="entry name" value="YkvI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37814">
        <property type="entry name" value="PTHR37814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="193"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="227"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="268"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="308"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="332"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="361" mass="39665" checksum="FBB32AA93B967D83" modified="2016-01-20" version="1">MESQNVYRSKTILKFAGAFIAWVIGSGFATGQEVLQFFTSYGYLSYGVVLLNLIGFIFLGQVLLITGYEHKAEKSFNQFKFFCGEKVGTFYSWLIPITLVLVMPVLISGAGATLSEYYGINHYIGSALMAGMVLCAYLIGFERLIKIVSTIGPVIILFSLMVGTVSVIRDFDHFVTVSNSEGLLRESQSSPHWALSSILYLSLNFLSGSTYFTELGKSSGHRNDAKYGALLGATALVLSIAIMNTAILLNAENTAVLAIPVLFLAKEISYSIGAVFSIVLILGMFSSCSAMMWSVCNRFTWGGKQGNRLFAIFVAIFIFVLGLFSFSDLLGVFYPLVGYMGLLYIGCVIYKGIKHQFETRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XT05</accession>
    <name>A0A0P6XT05_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_12310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76116">
        <property type="protein sequence ID" value="KPL76116"/>
        <property type="gene ID" value="ADN00_12310"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="61" mass="6756" checksum="36B12CBBDE161472" modified="2016-01-20" version="1">MQPLPESAVAEMLETPSPGCADPFPGEKAREGVKMRWLRWTVCWRAAYYAAPTEIRGCGDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XT17</accession>
    <name>A0A0P6XT17_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">30S ribosomal protein S4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpsD</name>
        <name evidence="9" type="ORF">ADN00_12475</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the body of the 30S subunit.</text>
    </comment>
    <comment type="function">
        <text evidence="6">With S5 and S12 plays an important role in translational accuracy.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the 30S ribosomal subunit. Contacts protein S5. The interaction surface between S4 and S5 is involved in control of translational fidelity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the universal ribosomal protein uS4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063345.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12475"/>
    <dbReference type="EnsemblBacteria" id="KPL76143">
        <property type="protein sequence ID" value="KPL76143"/>
        <property type="gene ID" value="ADN00_12475"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3976"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01306_B">
        <property type="entry name" value="Ribosomal_S4_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022801">
        <property type="entry name" value="Ribosomal_S4/S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001912">
        <property type="entry name" value="Ribosomal_S4/S9_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005709">
        <property type="entry name" value="Ribosomal_S4_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831">
        <property type="entry name" value="PTHR11831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11831:SF4">
        <property type="entry name" value="PTHR11831:SF4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00163">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01390">
        <property type="entry name" value="Ribosomal_S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01017">
        <property type="entry name" value="rpsD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_S4" evidence="8">
        <location>
            <begin position="3"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="S4" evidence="7">
        <location>
            <begin position="101"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL76143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="211" mass="24554" checksum="922DB66972C4E422" modified="2016-01-20" version="1">MARYIGPACKLCRREGEKLFLKGERCFTPKCAFEHRAYAPGEHGRAHNVRGRESDYARQLRAKQKARRIYGVLERQFRRYFEVALGKRGLTGLNLLQTLELRMDNVVYRMGLAASRNQARQMVSHGHFMVNGRRTDVPSTLLKVGDRIEVREESAKKPMFKDLAEVAESRNSALWLERDLKNWTGRVLRLPERAEIDGNLDEQLIVEYYSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XT23</accession>
    <name>A0A0P6XT23_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8">30S ribosomal protein S3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rpsC</name>
        <name evidence="12" type="ORF">ADN00_12570</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">Binds the lower part of the 30S subunit head. Binds mRNA in the 70S ribosome, positioning it for translation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Part of the 30S ribosomal subunit. Forms a tight complex with proteins S10 and S14.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8 10">Belongs to the universal ribosomal protein uS3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063364.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12570"/>
    <dbReference type="EnsemblBacteria" id="KPL76161">
        <property type="protein sequence ID" value="KPL76161"/>
        <property type="gene ID" value="ADN00_12570"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3995"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1140.32">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01309_B">
        <property type="entry name" value="Ribosomal_S3_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004044">
        <property type="entry name" value="KH_dom_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005704">
        <property type="entry name" value="Ribosomal_S3_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001351">
        <property type="entry name" value="Ribosomal_S3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036419">
        <property type="entry name" value="Ribosomal_S3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018280">
        <property type="entry name" value="Ribosomal_S3_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07650">
        <property type="entry name" value="KH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00189">
        <property type="entry name" value="Ribosomal_S3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54821">
        <property type="entry name" value="SSF54821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01009">
        <property type="entry name" value="rpsC_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50823">
        <property type="entry name" value="KH_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00548">
        <property type="entry name" value="RIBOSOMAL_S3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8 10" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 8 10" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 8 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 8" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="KH type-2" evidence="11">
        <location>
            <begin position="39"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01309"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KPL76161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="226" mass="25517" checksum="E6B7CD30CEB00344" modified="2016-01-20" version="1">MGRKVHPIGFRLSINKTWDGRWYADGPQYIDQLHQDFQIRELIMKEAGRAGVSRVEVERFPGKVKVVVNTAKPGILIGRKGETVKKIRQDLEALTGKRIDLEIKEIKSPDLDAYLVAENVGGQIARRVSYRRAMKRAIQQAMRQGALGIKISVSGRLAGAEMARTVWLREGRVPLQTLRADIDFSQTEALTTYGKIGIKVWVYRGDVLSREIEEKVQPTEGVYVSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XTN7</accession>
    <name>A0A0P6XTN7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_11130</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063087.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76582">
        <property type="protein sequence ID" value="KPL76582"/>
        <property type="gene ID" value="ADN00_11130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012318">
        <property type="entry name" value="HTH_CRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13545">
        <property type="entry name" value="HTH_Crp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00419">
        <property type="entry name" value="HTH_CRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51063">
        <property type="entry name" value="HTH_CRP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="2">
        <location>
            <begin position="13"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="HTH crp-type" evidence="3">
        <location>
            <begin position="148"/>
            <end position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL76582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="221" mass="24541" checksum="A306DDCB4C6DF1AB" modified="2016-01-20" version="1">MTSLLPFIAQQPLFSGLSEAAMDSLARSALQREYSAEQIVQVEGDPCRWVAFVQSGAARVYRLTLSGREQVLSNVGPGMHFNSVPALEENGRLRASVRALTPLTLLLIPVEDYRRLLQAHPDLAMAVLRDFARRLDHLTNLVEDLSLRSVRGRLARFLLEQADSGEVSAQWTQDEIAAHLGTVRDVIGRALRGFMDAGLVRREGAKLLLLDRARLEEEAQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XU06</accession>
    <name>A0A0P6XU06_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_01920</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000007">
        <property type="protein sequence ID" value="KPL80052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061275.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000007.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01920"/>
    <dbReference type="EnsemblBacteria" id="KPL80052">
        <property type="protein sequence ID" value="KPL80052"/>
        <property type="gene ID" value="ADN00_01920"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2310"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="232"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="275"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="4"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL80052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="320" mass="36230" checksum="E368553B2A1FCE0A" modified="2016-01-20" version="1">MYLSVVVPVYNERDNLPLLYQAVVDALKPIEKPWELILVDDGSRDDSLPVLESLADSDPQRVRVIALRRNFGQTAAIAAGIDHATGAVVVLMDADLQNDPQDIPMMLEKLEQGYDVISGWRKNRQDTFITRTLPSNLANWLISKTTGVKLHDYGCTLKAYRREVITGFRLYGEMHRFIPVFANSVGARILEVPVNHHPRKFGKAKYGLERTFKVVLDLFTVQFLSRYANKPIYLFGGTGSVLILVSGLVLFYLFIRRIFFDVSVMNSPLFQISTMVAILGFQSILMGLIAELLARTYHESQGKPTYTVRKKINFTEDDHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XU24</accession>
    <name>A0A0P6XU24_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Peroxiredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_02020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000007">
        <property type="protein sequence ID" value="KPL80070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061295.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000007.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80070">
        <property type="protein sequence ID" value="KPL80070"/>
        <property type="gene ID" value="ADN00_02020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003718">
        <property type="entry name" value="OsmC/Ohr_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036102">
        <property type="entry name" value="OsmC/Ohrsf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02566">
        <property type="entry name" value="OsmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82784">
        <property type="entry name" value="SSF82784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL80070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="148" mass="15975" checksum="1E99A77B3B7AAF94" modified="2016-01-20" version="1">MALVTFKAVSRKLPTGLAVENESRGFKIIMDEPAELGGTDLGMNPVEALLTALGSCLVIVVSAFAPAHGIKVEDLVVETEGDLDTDGFLKGKEGVRPGYQNVRFTIRFQSDASEEKLREFKKFVESRCPVSDTLMNGTTVIANDLVIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XU90</accession>
    <name>A0A0P6XU90_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78702.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061971.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78702">
        <property type="protein sequence ID" value="KPL78702"/>
        <property type="gene ID" value="ADN00_05500"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1576"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78702.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="638" mass="67759" checksum="425204B39AAC3D78" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUH1</accession>
    <name>A0A0P6XUH1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_14925</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000036">
        <property type="protein sequence ID" value="KPL73081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063832.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000036.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14925"/>
    <dbReference type="EnsemblBacteria" id="KPL73081">
        <property type="protein sequence ID" value="KPL73081"/>
        <property type="gene ID" value="ADN00_14925"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1848"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL73081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="365" mass="40385" checksum="1EEF113CFD55E162" modified="2016-01-20" version="1">MLNLAYFISPHGFGHASRSVAVMQSLLARSPHIHFHIFTLVPGWFFEDALPASCFTLHKERSDIGLVQRSPLEEDLPATISALHQYFPFQPELLSCLAASLVNCRCQAVLCDIAPLGIAAAQAAGIPSILIENFTWDWIYEGYLSTQPAFAQIIPGLAQVFRQADHHIQTQPLCQPSPAADLTTHPVSRRPKSPPSEVRNRLGIKDNNPAVLITMGGIPEKYAALDQLRKLSSVWFMLPGSSNEHQIQDNLVLLPHRSAFYHPDLVNASQAVIGKLGYSTISEVYHAGLAFGYIPRDQFRESPLLSAYVDQNFNAICISDQDFYSGKWINHMDALLSAPRLVRAVPNGADQISEFILKHLSAQSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XV01</accession>
    <name>A0A0P6XV01_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7 9">GTPase Der</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">GTP-binding protein EngA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">der</name>
        <name evidence="11" type="ORF">ADN00_03965</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 9">GTPase that plays an essential role in the late steps of ribosome biogenesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Associates with the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8 9">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. EngA (Der) GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061666.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03965"/>
    <dbReference type="EnsemblBacteria" id="KPL79049">
        <property type="protein sequence ID" value="KPL79049"/>
        <property type="gene ID" value="ADN00_03965"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.149"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00195">
        <property type="entry name" value="GTPase_Der"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031166">
        <property type="entry name" value="G_ENGA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016484">
        <property type="entry name" value="GTP-bd_EngA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032859">
        <property type="entry name" value="KH_dom-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14714">
        <property type="entry name" value="KH_dom-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006485">
        <property type="entry name" value="GTP-binding_EngA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03594">
        <property type="entry name" value="GTPase_EngA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51712">
        <property type="entry name" value="G_ENGA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="5 7 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 7" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="EngA-type G" evidence="10">
        <location>
            <begin position="4"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="EngA-type G" evidence="10">
        <location>
            <begin position="194"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="10"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="57"/>
            <end position="61"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="138"/>
            <end position="141"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="200"/>
            <end position="207"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="247"/>
            <end position="251"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="312"/>
            <end position="315"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL79049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="456" mass="50593" checksum="9EB8F8054722DB25" modified="2016-01-20" version="1">MRKPVVVLVGRPNVGKSTLFNRLAGERLAIVDDVPGTTRDRLLAEGEWTGHVFDVMDTGGIDPTTGGKDPLSIGSADYIEQIRVQAKAALELADVVLFLVDAEAGVTPADLEVAQILRRNQKKEEDGRLNPPVLLVVNKADNNALRNMASQFYELGMGDPYAISAVHGTGTGDLLDELVANFPQEPEEEGEPSVKIAIVGKPNAGKSSLLNCLMGEERAIVSPIAGTTRDAVDTFMMYNDIPVTLIDTAGIRRRGKVEPGVEKYSVLRAIRAIERADVALLVIDATTGITAQDTHIAGFILEAWKSTVVIVNKWDAVEKDNETMNLYTQKIRQELNFMDYVPILFISAKTGKRVDQVLPTALRVQEERLVRLSTSQLNKVIQDAQARHQPTTKSGQTLKIYYGTQVRSDPPTFMLYCNDPKLAHFSYRRFLENRIRENYTYLGTPIRLVFKSRREK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XV37</accession>
    <name>A0A0P6XV37_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_04305</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061726.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04305"/>
    <dbReference type="EnsemblBacteria" id="KPL79095">
        <property type="protein sequence ID" value="KPL79095"/>
        <property type="gene ID" value="ADN00_04305"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001694">
        <property type="entry name" value="NADH_UbQ_OxRdtase_su1/FPO"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00146">
        <property type="entry name" value="NADHdh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="141"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="174"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="234"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="260"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="284"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL79095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="303" mass="32889" checksum="F52779EFA97F112E" modified="2016-01-20" version="1">MNNILPLVALVLFPGGLFLLGSGLAYEWVDRKLIARFQNRFGPRWFQPLADVIKLLVKEEIVPQGVNAFLFVLLPVLGLAAALTAALYVPMAGLAPSFSFRGDLVVTLYLLSVLTLCLGLAGANSADRFSLIGATRTLTQVFSYEAPFLLAMLGPAIVTGSWQISEVNTYAQSNLWLIIAQPIGFLVALVGLMGKLEMPPFDAPEAETEIVSGALTEYSGRGYALFRLGKNVELVIGLTLVAAFYLGGLASPLDFLWKTLALLLVLALLQTLFARLRIDQTVGLWWRIGTLLALVQLLVLIIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XWH3</accession>
    <name>A0A0P6XWH3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cell shape-determining protein MreB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">mreB</name>
        <name evidence="3" type="ORF">ADN00_02225</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Forms polymers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="2">Membrane-associated.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the FtsA/MreB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000009">
        <property type="protein sequence ID" value="KPL79799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061331.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000009.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02225"/>
    <dbReference type="EnsemblBacteria" id="KPL79799">
        <property type="protein sequence ID" value="KPL79799"/>
        <property type="gene ID" value="ADN00_02225"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2767"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000902">
        <property type="term" value="P:cell morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd10225">
        <property type="entry name" value="MreB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02207">
        <property type="entry name" value="MreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004753">
        <property type="entry name" value="MreB"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01652">
        <property type="entry name" value="SHAPEPROTEIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00904">
        <property type="entry name" value="mreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0133">Cell shape</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="14"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="160"/>
            <end position="162"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="208"/>
            <end position="211"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="344" mass="36865" checksum="04C4B802F1F2EEB7" modified="2016-01-20" version="1">MGLFSLDIGIDLGTANTLVNVHGKGIVINEPSWVTIEKRSRKPLAIGARAKEMVGRTPANVIAIRPLRDGVISEFEITQAMLGYFIGKAHQQTIVPLPRPRVVVGIPSGATEVEKRAVLDASMAAGAREVHLIEEPRAAALGAGLPISEVRGTMIVDIGGGTTEVALMSTGGIVVSRSLRVAGDELDQDIITYIRNKYNLFIGERMAEQVKITIGSAYPLTTEKTMTVRGRNLVTGLPEAIEVSSVEIREAISGSIQVIVDTIKDALDEAPPEIVADLIESGICLAGGGAQLQGLVERLADELNLRVWVAEDPMTCVARGAGIILENLDTYRDFLVSLDRRNSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XWU8</accession>
    <name>A0A0P6XWU8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Histidine kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_02035</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000007">
        <property type="protein sequence ID" value="KPL80073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061298.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000007.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02035"/>
    <dbReference type="EnsemblBacteria" id="KPL80073">
        <property type="protein sequence ID" value="KPL80073"/>
        <property type="gene ID" value="ADN00_02035"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2333"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Histidine kinase" evidence="1">
        <location>
            <begin position="171"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="382" mass="42956" checksum="A761280E2DAE061A" modified="2016-01-20" version="1">MSDSLVAMPTAFLPAERRSKEEVRQQAAVLDRSAVMKAIIDASPDILMVLNSDRQIVYGNRRLMEYLELEDGDAVTGLRPGEALGCLHAFETEGGCGTTEFCKTCGAARAVVGGLTGKQNAQECRILQEKTHGSLDLLVHSSPLEVEGEKYAVVSLQDISHEKRRRVLERLFFHDLLNSAGGMRGLVELAKISSGAEQQDLLDTLYQLTDEILEEVQAQKLLVDLERDEYTESAEKLNSLEFLRELRNVFRHHSASANRMIEIDERARDINFTSDRKLLWRVMGNLIKNALEASKAGQEIKLGCENADGKLEFWVYNRGYIPRETQLQIFQRSFSTKGSGRGLGTYSVRMITEKYLKGRAFFTSTPEIGTTFFIHLPMRLEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XXV3</accession>
    <name>A0A0P6XXV3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">2,3-bisphosphoglycerate-dependent phosphoglycerate mutase</fullName>
            <shortName evidence="4">BPG-dependent PGAM</shortName>
            <shortName evidence="4">PGAM</shortName>
            <shortName evidence="4">Phosphoglyceromutase</shortName>
            <shortName evidence="4">dPGM</shortName>
            <ecNumber evidence="4 5">5.4.2.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">gpmA</name>
        <name evidence="6" type="ORF">ADN00_01180</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 5">
            <text>(2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate</text>
            <dbReference type="Rhea" id="RHEA:15901"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="EC" id="5.4.2.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 5">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.11" evidence="4 5"/>
    <dbReference type="EMBL" id="LGCL01000003">
        <property type="protein sequence ID" value="KPL80832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061132.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01180"/>
    <dbReference type="EnsemblBacteria" id="KPL80832">
        <property type="protein sequence ID" value="KPL80832"/>
        <property type="gene ID" value="ADN00_01180"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1984"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00186"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046538">
        <property type="term" value="F:2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01039">
        <property type="entry name" value="PGAM_GpmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001345">
        <property type="entry name" value="PG/BPGM_mutase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005952">
        <property type="entry name" value="Phosphogly_mut1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11931">
        <property type="entry name" value="PTHR11931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01258">
        <property type="entry name" value="pgm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00175">
        <property type="entry name" value="PG_MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="2 4" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="8"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="21"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="87"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="114"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="183"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="4">
        <location>
            <position position="9"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="4">
        <location>
            <position position="87"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="4">
        <location>
            <position position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL80832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="249" mass="28478" checksum="2BB13C7F3AED654E" modified="2016-01-20" version="1">MIKLVLLRHGESDWNKQNRFTGWTDVDLSEKGIEEAKRAGELLKKEGFTFDIAYTSVLKRAIRTLWLTLDGMDLMWIPVVRNWRLNERHYGALQGLNKAETAAKFGDEQVLIWRRSYDIQPPKLEKSDERYPGHDPRYADLTEEELPLTECLKDTVARFLPLWHETIAPVIKSGKKVLIAAHGNSLRALVKYLDNIPDEEIVSLNIPTGIPLVYELDDDLKPIRHYYLGDQAAVEAAMQAVANQGKAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XYQ0</accession>
    <name>A0A0P6XYQ0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Tyrosine--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Tyrosyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">ADN00_07045</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-tyrosine + tRNA(Tyr) = AMP + diphosphate + H(+) + L-tyrosyl-tRNA(Tyr)</text>
            <dbReference type="Rhea" id="RHEA:10220"/>
            <dbReference type="Rhea" id="RHEA-COMP:9706"/>
            <dbReference type="Rhea" id="RHEA-COMP:9707"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78536"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.1" evidence="2"/>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07045"/>
    <dbReference type="EnsemblBacteria" id="KPL78347">
        <property type="protein sequence ID" value="KPL78347"/>
        <property type="gene ID" value="ADN00_07045"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3226"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004831">
        <property type="term" value="F:tyrosine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006437">
        <property type="term" value="P:tyrosyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00805">
        <property type="entry name" value="TyrRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002307">
        <property type="entry name" value="Tyr-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024088">
        <property type="entry name" value="Tyr-tRNA-ligase_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024108">
        <property type="entry name" value="Tyr-tRNA-ligase_bac_2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11766">
        <property type="entry name" value="PTHR11766"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11766:SF1">
        <property type="entry name" value="PTHR11766:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01040">
        <property type="entry name" value="TRNASYNTHTYR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00234">
        <property type="entry name" value="tyrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S4" evidence="11">
        <location>
            <begin position="336"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00033323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KPL78347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="396" mass="44570" checksum="DEA289ECAC335D33" modified="2016-01-20" version="1">MMQGTEYGDDNLKTAMTRELRERLVEAQKEGRPLRVYCGFDPRTADLHLGHTVPMRKMRQFQELGHDVVFLVGNFTSLIGDPSDKDVLRPQLTAEQVAENARTYAEQAYRILEKDKTRIAFNAEWLSKLTFEDLIKLSSNFTIQQFLTRENFRKRWDKGDALYMHELFYSIMQGYDAYALKADVQIGGTDQLFNIVTAARKIMTYLDAKPNIAIILGILPGTDGTVKMSKSLGNHIPILTGPEDMYGKVMSIPDAAMPQYSRLVTRWTPDVIHAMESALKEGTLHPRDAKMKLAWEITSAFYSDEAANDAQEAFVRLFQKGDVPEEMAEFGLDAAMPLADLLVATGMAESKSQARRLIDQKGVKLDGEVLTDARAAVPHAGVLQVGKRNYVRIIEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XZ03</accession>
    <name>A0A0P6XZ03_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_13660</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the glycosyltransferase 87 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063582.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000032.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74343">
        <property type="protein sequence ID" value="KPL74343"/>
        <property type="gene ID" value="ADN00_13660"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018584">
        <property type="entry name" value="GT87"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09594">
        <property type="entry name" value="GT87"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="87"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="136"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="185"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="219"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="276"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="302"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="325"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="352"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="383"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL74343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="422" mass="47458" checksum="2C0BF9DFD6907477" modified="2016-01-20" version="1">MNQLRTKPTLNTLWIILSAVILLGLLTSANYQYSKQNPGGTDFMVHWMGTRTYLMDGLSPYSDETSLKIQTFTYGRAAGPGEHELRVAYPLYSMFLFMPFAAAADFDLARALWMTVLEVSLVGLSLISIQLTDWKPSLLMLGVFLGFSLLWYHAVRPLILGNAVILVAVMLAGVLLAIRKRADELAGVLLAFSTIKPQVVALFIVFILFWAVANRRWKLVGWFFGILALLVATASLLIPDWILQNLREILRYPGYNPPGTLGAALAVWLPDAGKRIGWAVTGVLSLVLLLEWNMARRANFRGFLWAACLTLAASLWIGIQTDPGNFIVAFPGIVLTFSLWDKRWRVGGKKIIYAFSAVLMVGIWAIFLATVEYSYQPIQSPVMFIPLPLALFVMLYWVRWWAVRPPSTWMDSIYELENPELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y035</accession>
    <name>A0A0P6Y035_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">ATP-dependent 6-phosphofructokinase</fullName>
            <shortName evidence="10">ATP-PFK</shortName>
            <shortName evidence="10">Phosphofructokinase</shortName>
            <ecNumber evidence="10">2.7.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Phosphohexokinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">pfkA</name>
        <name evidence="12" type="ORF">ADN00_13260</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6-bisphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16109"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 10">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homodimer or homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.11" evidence="10"/>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13260"/>
    <dbReference type="EnsemblBacteria" id="KPL74809">
        <property type="protein sequence ID" value="KPL74809"/>
        <property type="gene ID" value="ADN00_13260"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1134"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00182"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003872">
        <property type="term" value="F:6-phosphofructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047334">
        <property type="term" value="F:diphosphate-fructose-6-phosphate 1-phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01976">
        <property type="entry name" value="Phosphofructokinase_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022953">
        <property type="entry name" value="ATP_PFK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012003">
        <property type="entry name" value="ATP_PFK_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015912">
        <property type="entry name" value="Phosphofructokinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000023">
        <property type="entry name" value="Phosphofructokinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012829">
        <property type="entry name" value="Phosphofructokinase_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035966">
        <property type="entry name" value="PKF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00365">
        <property type="entry name" value="PFK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000532">
        <property type="entry name" value="ATP_PFK_prok"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00476">
        <property type="entry name" value="PHFRCTKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53784">
        <property type="entry name" value="SSF53784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00433">
        <property type="entry name" value="PHOSPHOFRUCTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 10" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="7 10 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PFK" evidence="11">
        <location>
            <begin position="17"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="152"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="196"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="298"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="154"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="25"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="89"/>
            <end position="90"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="129"/>
            <end position="132"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="249"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="292"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="site" description="Important for substrate specificity; cannot use PPi as phosphoryl donor" evidence="10">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
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        </source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="KPL74809.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="384" mass="40752" checksum="B5C6C94BF9FB803C" modified="2016-01-20" version="1">MAIIKSRGKESEGKLKRLAILTGGGDAPGLNAVIRAAVKTVYHQCDCEILGVKDGFDGFLETGGVNPLTQADVRGILPRGGTILGTANRGNPFAREVIHNGQVVIEDLSGQIIDAIHALNLDVLIVVGGDGTLRIANELFQKGVPVVGVPKTIDNDIYGTDFSFGFDTAVNIASEAIDRLHTTAESHHRVMVLELMGRDAGFIALHAGMAGGADVILIPEIPFHLDAICYKIQERVRSGSHFSIVAVAEGARPFGKEQVFAIPGSETYAARLGGVGNLVGKYINDLCGIETRVIVLGHLQRGGSPTAFDRQLATRLGSAAVRLALNNGFGRMVALQGQRITDISLDEALSVPKRVDIHGDTLQTARALGIAFGDETLPEEVYTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y360</accession>
    <name>A0A0P6Y360_9CHLR</name>
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        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_11990</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
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            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
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            <taxon>Anaerolineaceae</taxon>
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    <reference evidence="1 2" key="1">
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            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="KPL76062">
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        <property type="gene ID" value="ADN00_11990"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
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    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Capsule_polysaccharide_synth"/>
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    </dbReference>
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            <dbReference type="EMBL" id="KPL76062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
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        </source>
    </evidence>
    <sequence length="539" mass="60529" checksum="759ACA75A3A9E9F5" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
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    <name>A0A0P6Y3A6_9CHLR</name>
    <protein>
        <submittedName>
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        <lineage>
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                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
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    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
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            <begin position="1"/>
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    <feature type="compositionally biased region" description="Pro residues" evidence="1">
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        </location>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="KPL76108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
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</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y4M3</accession>
    <name>A0A0P6Y4M3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
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    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
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                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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        <property type="protein sequence ID" value="KPL80056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061279.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000007.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80056">
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        <property type="gene ID" value="ADN00_01940"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2314"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="51"/>
        </location>
    </feature>
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        </location>
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            <end position="368"/>
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        </location>
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    <feature type="transmembrane region" description="Helical" evidence="1">
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            <end position="496"/>
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="508"/>
            <end position="527"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="655" mass="69364" checksum="0E26A07084D27805" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y5K5</accession>
    <name>A0A0P6Y5K5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
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    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
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        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062811.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09750"/>
    <dbReference type="EnsemblBacteria" id="KPL76876">
        <property type="protein sequence ID" value="KPL76876"/>
        <property type="gene ID" value="ADN00_09750"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2407"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01572">
        <property type="entry name" value="UPF0397"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009825">
        <property type="entry name" value="ECF_substrate-spec-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022914">
        <property type="entry name" value="UPF0397"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07155">
        <property type="entry name" value="ECF-ribofla_trS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="43"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="117"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="151"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL76876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="185" mass="19695" checksum="E1E0FC5DC42D0C7A" modified="2016-01-20" version="1">MKDLFKVNTRTIVATGLGAAIFTLLFMYVKVPSPIPETSFQTAYGVSALFATLFGPIAGALISFIGHALSDAIQYGSPWWSWVIASGVSGLIFGFAFNRTKVEEGEFKGKDILTFNVIQVIGNAIAWIVVAPLLDILIYQEPASLVFTQGVTAAIMNAISAGVIGTLLLVAYAATRTKKGSLSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y5M4</accession>
    <name>A0A0P6Y5M4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_09845</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062829.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76894">
        <property type="protein sequence ID" value="KPL76894"/>
        <property type="gene ID" value="ADN00_09845"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="397" mass="44218" checksum="FA4BB67687EF43B2" modified="2016-01-20" version="1">MVTQNPSGPVALKCPQCNGDLPLTTLDAIICPYCGSSLILGRSQPGAPNAPSGETLVHGLRLKPLTCTDDQGTRLPLFRMLIPAGWQFQGGCRWQLDNPGMPAVVQFLVANPQGAEAFEVLPNMNFVWNNSPLSRVLFPAGSRYFGAEVRPPVSIADAFHSFILPRFRGAAQGLQIESITPLPDLPRLVKSDAAITPGGSAEGGKARVRYSLQGQDFEEEFYGVVEVFRVPGGSLLSPSEFIVWFIDYLFSFRAAAGRLDATADLFTVMIQSFELNPEWYAAFKTIVQHMAQRQITHIRHIGEIGNILAEAGRQMREQNLSDWYRRQDIYDRLAVDRSRAIRDVDGFYDPHREEVVELPSGYGHAWANNLGEYILTEDSSFNPNLYSTQHWEPMTQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y5X9</accession>
    <name>A0A0P6Y5X9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_10495</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062952.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10495"/>
    <dbReference type="EnsemblBacteria" id="KPL76995">
        <property type="protein sequence ID" value="KPL76995"/>
        <property type="gene ID" value="ADN00_10495"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029150">
        <property type="entry name" value="dCache_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029151">
        <property type="entry name" value="Sensor-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14827">
        <property type="entry name" value="dCache_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103190">
        <property type="entry name" value="SSF103190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="146"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="432"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="4"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="5">
        <location>
            <begin position="452"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="4">
        <location>
            <begin position="540"/>
            <end position="675"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL76995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="749" mass="82602" checksum="395F7746AA98B100" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y6E6</accession>
    <name>A0A0P6Y6E6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AP_endonuc_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_00200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060940.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00200"/>
    <dbReference type="EnsemblBacteria" id="KPL81007">
        <property type="protein sequence ID" value="KPL81007"/>
        <property type="gene ID" value="ADN00_00200"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3434"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001719">
        <property type="entry name" value="AP_endonuc_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21445">
        <property type="entry name" value="PTHR21445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00518">
        <property type="entry name" value="AP2Ec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="1">
        <location>
            <begin position="28"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL81007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="282" mass="30932" checksum="508F9D58625C4E53" modified="2016-01-20" version="1">MADPFRFGTVGSPIATPKKPGGSVGAIQYLKEIGLSALELGWVRAVRVTEATCQEIKETSTQLDVAISIHAPYFINLNANADEWPKSRQRLMDAAHYGFLAGATDIIFHPGSYFSQPPESVLAVAIPRLAACIRELRDQGNPVILRPETMGKSAMLGSLEDTLEMSKTVQGVEPCLDFAHLHARPGDGSVNTFAEWKEILTQYQQALGDASLSRLHIHLSGIEYGDKGEKNHLPLQESDLNLDALLDALADMRCAGRILCESPIMEEDALHMQNLWNQKTAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y6U4</accession>
    <name>A0A0P6Y6U4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Pyruvate formate-lyase-activating enzyme</fullName>
            <ecNumber evidence="9">1.97.1.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">pflA</name>
        <name evidence="11" type="ORF">ADN00_09235</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Activation of pyruvate formate-lyase under anaerobic conditions by generation of an organic free radical, using S-adenosylmethionine and reduced flavodoxin as cosubstrates to produce 5'-deoxy-adenosine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>glycyl-[formate C-acetyltransferase] + reduced [flavodoxin] + S-adenosyl-L-methionine = 5'-deoxyadenosine + glycin-2-yl radical-[formate C-acetyltransferase] + H(+) + L-methionine + semiquinone [flavodoxin]</text>
            <dbReference type="Rhea" id="RHEA:19225"/>
            <dbReference type="Rhea" id="RHEA-COMP:10622"/>
            <dbReference type="Rhea" id="RHEA-COMP:12190"/>
            <dbReference type="Rhea" id="RHEA-COMP:12191"/>
            <dbReference type="Rhea" id="RHEA-COMP:14480"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:29947"/>
            <dbReference type="ChEBI" id="CHEBI:32722"/>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:140311"/>
            <dbReference type="EC" id="1.97.1.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="9">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the organic radical-activating enzymes family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.97.1.4" evidence="9"/>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062705.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09235"/>
    <dbReference type="EnsemblBacteria" id="KPL77305">
        <property type="protein sequence ID" value="KPL77305"/>
        <property type="gene ID" value="ADN00_09235"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4081"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043365">
        <property type="term" value="F:[formate-C-acetyltransferase]-activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034457">
        <property type="entry name" value="Organic_radical-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012839">
        <property type="entry name" value="Organic_radical_activase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012838">
        <property type="entry name" value="PFL1_activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001989">
        <property type="entry name" value="Radical_activat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30352">
        <property type="entry name" value="PTHR30352"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000371">
        <property type="entry name" value="PFL_act_enz"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02493">
        <property type="entry name" value="PFLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01087">
        <property type="entry name" value="RADICAL_ACTIVATING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 9" id="KW-0408">Iron</keyword>
    <keyword evidence="8 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="11" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 9 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="10">
        <location>
            <begin position="16"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU362053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL77305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="246" mass="27939" checksum="12735790C482C79A" modified="2016-01-20" version="1">MGAVLRIHSIETFGTSDGPGIRLVIFIQGCPLRCLYCHNPDSQALTSKFATDLPLEDLLERLEKQRPYFKNKGGVTFSGGEPTVQAGALLEYLPAVREAGYHIALDTCGAIYNRRVNQLYDHSDLIILDVKHIDPDWHRRITGSPIDPVLKNAAYREQTGKPMWLRYVLVPGYTDQPQYLEQWGKVFGDYKSVERVEILPYHTLGVHKYTEMGRDYPLVGVDTPTNEQVEKAAQIFKEYFSNVVVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y7R3</accession>
    <name>A0A0P6Y7R3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA_edit domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_08835</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000022">
        <property type="protein sequence ID" value="KPL77680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062627.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000022.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77680">
        <property type="protein sequence ID" value="KPL77680"/>
        <property type="gene ID" value="ADN00_08835"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1489"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.960.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036754">
        <property type="entry name" value="YbaK/aa-tRNA-synt-asso_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007214">
        <property type="entry name" value="YbaK/aa-tRNA-synth-assoc-dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04073">
        <property type="entry name" value="tRNA_edit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55826">
        <property type="entry name" value="SSF55826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA_edit" evidence="1">
        <location>
            <begin position="32"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="158" mass="16746" checksum="D6F31299EF719FB8" modified="2016-01-20" version="1">MAESLSDSAKRVQQALKAIGFELRVVEMPDSTRTSVEAAQAVGCEVAQIAKSLVFKAASGRAVLVIASGMNRVNEKRVAAELGESLGKADADFVRQQTGFAIGGIPPVGHIQPLETFIDEDLLQFETIWAAAGTPHAVFQLTPAELQKMTGARVIGVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y889</accession>
    <name>A0A0P6Y889_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cytidylate kinase</fullName>
            <shortName evidence="8">CK</shortName>
            <ecNumber evidence="8">2.7.4.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Cytidine monophosphate kinase</fullName>
            <shortName evidence="8">CMP kinase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">cmk</name>
        <name evidence="10" type="ORF">ADN00_08370</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + CMP = ADP + CDP</text>
            <dbReference type="Rhea" id="RHEA:11600"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58069"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.25"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 8">
            <text>ATP + dCMP = ADP + dCDP</text>
            <dbReference type="Rhea" id="RHEA:25094"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57566"/>
            <dbReference type="ChEBI" id="CHEBI:58593"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.25"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the cytidylate kinase family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.25" evidence="8"/>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062532.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08370"/>
    <dbReference type="EnsemblBacteria" id="KPL77881">
        <property type="protein sequence ID" value="KPL77881"/>
        <property type="gene ID" value="ADN00_08370"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.676"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036430">
        <property type="term" value="F:CMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036431">
        <property type="term" value="F:dCMP kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006220">
        <property type="term" value="P:pyrimidine nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02020">
        <property type="entry name" value="CMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00238">
        <property type="entry name" value="Cytidyl_kinase_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003136">
        <property type="entry name" value="Cytidylate_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011994">
        <property type="entry name" value="Cytidylate_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02224">
        <property type="entry name" value="Cytidylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00017">
        <property type="entry name" value="cmk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cytidylate_kin" evidence="9">
        <location>
            <begin position="7"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="11"/>
            <end position="19"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL77881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="224" mass="24957" checksum="2CFE897BFA9EF38B" modified="2016-01-20" version="1">MKYPKHIAIDGPAASGKSTVAEIVAHQIGYLFFDTGVMYRAVTLASLQRLNGVNDEKAVSDLAEAIDIDVRPPSVQDERKYDVLVDGVDVTWDIRKPEVDANVSRVSAYAGVRKAMTAQQRKIGERGQVVMVGRDIGTVVLPDAELKVFLDASVEERARRRYDEVQHRNQPEPYEQILQAMKKRDEIDSTRDLAPLCPADDAHILNTEGMTIQQVVDAILAFLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YAH6</accession>
    <name>A0A0P6YAH6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78869">
        <property type="protein sequence ID" value="KPL78869"/>
        <property type="gene ID" value="ADN00_05270"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="59" mass="6402" checksum="AA94A8810AD43634" modified="2016-01-20" version="1">MIQSPQQSPLRLPIFSRKGCTLSPRTQWDRPGGLPGSPERRCLAQRPCPSFAGAPGLSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YAS0</accession>
    <name>A0A0P6YAS0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Lipoprotein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_03650</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061608.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03650"/>
    <dbReference type="EnsemblBacteria" id="KPL78997">
        <property type="protein sequence ID" value="KPL78997"/>
        <property type="gene ID" value="ADN00_03650"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.82"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003760">
        <property type="entry name" value="PnrA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02608">
        <property type="entry name" value="Bmp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0449">Lipoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133466" evidence="3">
        <location>
            <begin position="27"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="Bmp" evidence="4">
        <location>
            <begin position="71"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="34"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL78997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="435" mass="46998" checksum="32FA42E255F357EC" modified="2016-01-20" version="1">MKKHLLWRSLSLLMVVAFMLSACAPAATEAPAEAPVVEQPTAAPAATEAPTEAPTEAAAEAPAAPEELVFGLLMVGPYNDRGWSQAHYDAAEYVTEKMEGVSFVYVDKVNTADRPGTTGVQLAESLLDQGAKVIIFNSDDMKVDAVEFAKGHPDIPVIHASGDTVWKDGMNYEEIPNMSNIMGQMEYGKAMAGCAAALTTKTGQIGYLGPLINDETRRLAASVYLGARYCWENYLGKDPADLTFKVTWIGFWFNIPGFTADPTQVADDFYNSGFDVVVSGIDTTEALTEAKKMVESGKEVWAIPYDYKDACAEATEVCLGVPYFNWGPSYVKALQSIQDGSYASFFENSAPDWADINNPDTSMIGFKKGDALSEEAATNLDAFIAELAGGLNLWTGPLNYQDGSVFLAEGETATMQQIWYLGQLLEGMQGQSVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YFM3</accession>
    <name>A0A0P6YFM3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UPF0235 protein ADN00_00080</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_00080</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the UPF0235 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL80990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060920.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00080"/>
    <dbReference type="EnsemblBacteria" id="KPL80990">
        <property type="protein sequence ID" value="KPL80990"/>
        <property type="gene ID" value="ADN00_00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00634">
        <property type="entry name" value="UPF0235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005228">
        <property type="entry name" value="CHP00251"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003746">
        <property type="entry name" value="DUF167"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036591">
        <property type="entry name" value="YggU-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13420">
        <property type="entry name" value="PTHR13420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02594">
        <property type="entry name" value="DUF167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01152">
        <property type="entry name" value="DUF167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69786">
        <property type="entry name" value="SSF69786"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00251">
        <property type="entry name" value="TIGR00251"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL80990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="107" mass="11672" checksum="D7606500F6042A74" modified="2016-01-20" version="1">MKSNSPKFKDGKTGVALTVRVTPRSKKNEIVEILDDGTLKIRLTAPPLEGRANKVLIQFLAEVLSVSESRIDIVAGETGRNKLVTIEDMDAKDLQARISLALGVKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YFV6</accession>
    <name>A0A0P6YFV6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_00770</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061041.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00770"/>
    <dbReference type="EnsemblBacteria" id="KPL81091">
        <property type="protein sequence ID" value="KPL81091"/>
        <property type="gene ID" value="ADN00_00770"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3552"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043758">
        <property type="term" value="F:acetate-CoA ligase (ADP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043938">
        <property type="entry name" value="Ligase_CoA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032875">
        <property type="entry name" value="Succ_CoA_lig_flav_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13380">
        <property type="entry name" value="CoA_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19045">
        <property type="entry name" value="Ligase_CoA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13607">
        <property type="entry name" value="Succ_CoA_lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00881">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="SSF52210"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="79"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-grasp" evidence="3">
        <location>
            <begin position="490"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL81091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="698" mass="74770" checksum="7E69019198670297" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GKN2</accession>
    <name>A0A0N8GKN2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Diaminopimelate decarboxylase</fullName>
            <shortName evidence="2">DAP decarboxylase</shortName>
            <shortName evidence="2">DAPDC</shortName>
            <ecNumber evidence="2 3">4.1.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">lysA</name>
        <name evidence="6" type="ORF">ADN00_18590</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Specifically catalyzes the decarboxylation of meso-diaminopimelate (meso-DAP) to L-lysine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 3">
            <text>H(+) + meso-2,6-diaminoheptanedioate = CO2 + L-lysine</text>
            <dbReference type="Rhea" id="RHEA:15101"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:57791"/>
            <dbReference type="EC" id="4.1.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 2 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 3">Amino-acid biosynthesis; L-lysine biosynthesis via DAP pathway; L-lysine from DL-2,6-diaminopimelate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Orn/Lys/Arg decarboxylase class-II family. LysA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.20" evidence="2 3"/>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18590"/>
    <dbReference type="EnsemblBacteria" id="KPL70170">
        <property type="protein sequence ID" value="KPL70170"/>
        <property type="gene ID" value="ADN00_18590"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3027"/>
    <dbReference type="UniPathway" id="UPA00034">
        <property type="reaction ID" value="UER00027"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008836">
        <property type="term" value="F:diaminopimelate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009089">
        <property type="term" value="P:lysine biosynthetic process via diaminopimelate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06828">
        <property type="entry name" value="PLPDE_III_DapDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02120">
        <property type="entry name" value="LysA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009006">
        <property type="entry name" value="Ala_racemase/Decarboxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002986">
        <property type="entry name" value="DAP_deCOOHase_LysA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022643">
        <property type="entry name" value="De-COase2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022644">
        <property type="entry name" value="De-COase2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000183">
        <property type="entry name" value="Orn/DAP/Arg_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02784">
        <property type="entry name" value="Orn_Arg_deC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00278">
        <property type="entry name" value="Orn_DAP_Arg_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01181">
        <property type="entry name" value="DAPDCRBXLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01179">
        <property type="entry name" value="ODADCRBXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50621">
        <property type="entry name" value="SSF50621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01048">
        <property type="entry name" value="lysA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 3" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="2 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 3" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orn_Arg_deC_N" evidence="5">
        <location>
            <begin position="53"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="Orn_DAP_Arg_deC" evidence="4">
        <location>
            <begin position="291"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="2">
        <location>
            <begin position="283"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="286"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="323"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="327"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="355"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="383"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL70170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="425" mass="46561" checksum="53A3D584B47CC5C4" modified="2016-01-20" version="1">MSYQRDSAGRMQIAGCDVNALCDQWGTPLYLLDGRTVREQAASLARWGAAHYAGKFTVAYASKAYLSLKFAEKLAAMPVGIDTVSLGEMKIARKAGFDGERVHLHGNGKTEAELRFALEWGIDAIVVDSPEELQFLARLAENRQTQARIWLRITPGVDVDTHPHVQTGQTGSKFGISIPDGQAEALIRQALGEPWLALTGLHIHLGSQIFDAAPYQKAVEQLCLLAERAGYIPQKISTGGGWGVRYVPQHAENDGERWIRAVSETLMMESGKRGWPLPELVLEPGRWMAARAGVAVYSVTTSKTNGEGVYVIALDGGMADNPRPAMYSASYIAELAAREMPEARRESMLVGKFCETGDILIPSIQMPEVRRGERIAMPAAGAYQISMASNYNLAARPAVLWLEDGKAEVLQQREDPGERGYWMGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GL38</accession>
    <name>A0A0N8GL38_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_17150</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064275.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL71418">
        <property type="protein sequence ID" value="KPL71418"/>
        <property type="gene ID" value="ADN00_17150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL71418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="138" mass="15072" checksum="5C1A129FAE458D67" modified="2016-01-20" version="1">MTKITSGLLNDTLNLIQLARETALRSGRQAQASRFAPVEQNLQKAVTTARENRVAAPSQSGMMGQKDFKTLLNLSQNGGSHQASSMQIGERNQMVRAMASGGMSDLDIARQLGMTRQEVRLVVSVQRQMAYGKYEVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GL39</accession>
    <name>A0A0N8GL39_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Flagellar biosynthetic protein FliQ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">fliQ</name>
        <name evidence="10" type="ORF">ADN00_17195</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Role in flagellar biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="9">Bacterial flagellum basal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the FliQ/MopD/SpaQ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064284.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17195"/>
    <dbReference type="EnsemblBacteria" id="KPL71426">
        <property type="protein sequence ID" value="KPL71426"/>
        <property type="gene ID" value="ADN00_17195"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.501"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002191">
        <property type="entry name" value="Bac_export_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006305">
        <property type="entry name" value="FliQ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34040">
        <property type="entry name" value="PTHR34040"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01313">
        <property type="entry name" value="Bac_export_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004669">
        <property type="entry name" value="FliQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00952">
        <property type="entry name" value="TYPE3IMQPROT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01402">
        <property type="entry name" value="fliQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="4 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL71426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="89" mass="9478" checksum="FCBA875C795D7F13" modified="2016-01-20" version="1">MTETFVLSLAQNAITVALLLAAPILLVSLLVGSVISLIQAATQINEVTLTFIPKMIGIVLVLLLLGSWMLQQLVTFTSGLFESLPTLVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMK3</accession>
    <name>A0A0N8GMK3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_12920</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL75538">
        <property type="protein sequence ID" value="KPL75538"/>
        <property type="gene ID" value="ADN00_12920"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL75538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="166" mass="18714" checksum="27C89EB4A9419C63" modified="2016-01-20" version="1">MLEAPPVNLVGCYPQVSIQGFQYLVDFGAGETIRYHRVNKDKTCSCDTPFCEAVEVVRQYLQAGGQRAPEPAIIPTCPICGAKTYPDRNWDGKYTKSPGWRCEKGGLRHFLEAKCERIKKQLAENPWLIPPAPGYPGVKRDEVMTWEECEAINRKTFLETGYDPTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMR8</accession>
    <name>A0A0N8GMR8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">PMT_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ADN00_11955</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063247.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11955"/>
    <dbReference type="EnsemblBacteria" id="KPL76058">
        <property type="protein sequence ID" value="KPL76058"/>
        <property type="gene ID" value="ADN00_11955"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038731">
        <property type="entry name" value="RgtA/B/C-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13231">
        <property type="entry name" value="PMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="132"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="201"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="231"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="272"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="304"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="330"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="358"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="PMT_2" evidence="9">
        <location>
            <begin position="83"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL76058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="502" mass="57215" checksum="AAC147885E70D5A6" modified="2016-01-20" version="1">MNSLDQFLEKRKWLLALSLLFIFGLGLAVRFYDLQDPPMDFHPTRQFHSILMARGMYYQNLEGIPEWKREMAVQQWKAEGLIEPPFMEWLAAQTYRVTGQEAVWYARIYSILFWTAGGIGLFLLAKELAGNTAGIFAAAYYMLLKYAGIASRSFQPDPLMTALIVLALWALVRWSKEPNWKWSITAGLLAGLAILTKSVAVFFVGPAFLVVVVLSMGLLKALRSPKVWGMGVLAVVPYAMFHIYGMYISGLLREQFSLRFFPQLWTDPVFYLQWKGLIASTVGFEWFLLALLGIMLLRERTARGLLLAAFGGYFVYGLTFAYHISTHDYYQLPLIPLVALGLAGGVDSLVRGIQAKKWLAYPLLAGVLLFAVVTSAWDIRVALKRDDFRNEAVFWTRLSEKLGDNVSVVALSQNYSYPLKYWGWMQVTNWMTAGDFNYRKLAGVEFDVQKLFEEETAGKDYFIVTLLDDLNNQPEVKELLDANYPVFEQSSDYVIYDLRGQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GN69</accession>
    <name>A0A0N8GN69_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77266">
        <property type="protein sequence ID" value="KPL77266"/>
        <property type="gene ID" value="ADN00_09000"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4034"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="157" mass="17116" checksum="2398B7DCFA6D70F0" modified="2016-01-20" version="1">MLTGDKAETAVRIGAESGITAGQKAALTGRIIDRMEWAEVIRQASYCSVFARLTPSQKGILVRQLQKAGNTVAMVGDGPNDGIALKVADVGISLVNNSSSIARKLSQILINDLTDLITILDGAFRIKNRVRQCKLGRILIIVFSFIYLYFWVGSKFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GN76</accession>
    <name>A0A0N8GN76_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_09355</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09355"/>
    <dbReference type="EnsemblBacteria" id="KPL77322">
        <property type="protein sequence ID" value="KPL77322"/>
        <property type="gene ID" value="ADN00_09355"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4105"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039562">
        <property type="entry name" value="MFP_biotin_lipoyl_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13533">
        <property type="entry name" value="Biotin_lipoyl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="domain" description="Biotin_lipoyl_2" evidence="4">
        <location>
            <begin position="84"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="5">
        <location>
            <begin position="238"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="241"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL77322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="478" mass="50708" checksum="C730486097B768B7" modified="2016-01-20" version="1">MSLSLKKITGFFTKNKRNTVIGAVVVVTLLVVASALAFFKPAVGAVATATAEAAATPKYYTASVSVGDIELSASGSGNLISNSVVELAFSTSGTVTRLYVQPGDMVKTGDLLAELNASKELQAEVASRKLAVIEAQQALNQLQQNAEVSLASAFEAYVTAKADYEEALFNSQRTAYSRCDQQTTTRLAQTLERATEQLKKLTDTTTEEYTEAKNNYETASANYTYCVSYSEDEKTLANAALSVAEATLKQAEATYNKLKEASGVDPEELALAEANLSNAQSKLEIAQENLNGTTLIAPMDGTVISIAAGEGQRVEATTFITIADLKDLMMEVSVDESDLSFLTPGTHAEMEFDSIANTVFSGSVIQVDPTLSESMEYKLATGKIRMDIENNPAAEQLLLGLNASVTLIKERAENALLVPLEAVRDLGNGNTAVFVVGADGNLTFRAVEVGITTETQAQILSGLQEGDTVSTGLVSTNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-08-12" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNI7</accession>
    <name>A0A0N8GNI7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_06900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062250.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78210">
        <property type="protein sequence ID" value="KPL78210"/>
        <property type="gene ID" value="ADN00_06900"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="18"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="296" mass="33289" checksum="630FACAAEDC7F94A" modified="2016-01-20" version="1">MKNGIWKFLGEDPGLPGLTFRPVNVEEEKCQIDEVIARSCRADGMDVGRQMRSCGWRPLTGAQAVDHRESVAAELNGRMVAYAELRPMAGEGQIGLIYQMDGYVLPEWRCCGIGSALSEHIEEVCRRLEHKAEPRLDACARGVMTSRRQLLQDRGFIIWRYRFEFIHSNLSGVQAREMPAGWEVSDEQGEQAKLLEIRQNGIPAATVHLFADGMEHCQPGKEIGYLEIEPLEGTHLDPEMMGAILSRGLAASHARGLQQVLVNVDVNLPENAFDFGLYVELGFQLDHRLLMYRKNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNJ8</accession>
    <name>A0A0N8GNJ8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DeoR faimly transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_07520</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062365.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78298">
        <property type="protein sequence ID" value="KPL78298"/>
        <property type="gene ID" value="ADN00_07520"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3330"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014036">
        <property type="entry name" value="DeoR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001034">
        <property type="entry name" value="DeoR_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018356">
        <property type="entry name" value="Tscrpt_reg_HTH_DeoR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00455">
        <property type="entry name" value="DeoRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08220">
        <property type="entry name" value="HTH_DeoR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00037">
        <property type="entry name" value="HTHLACR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00420">
        <property type="entry name" value="HTH_DEOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00894">
        <property type="entry name" value="HTH_DEOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51000">
        <property type="entry name" value="HTH_DEOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH deoR-type" evidence="4">
        <location>
            <begin position="3"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL78298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="249" mass="26963" checksum="2BF28C2128061F3C" modified="2016-01-20" version="1">MLAAERRQYILECLQRDGRVLANQLSAELNVSEDTIRRDLREMAAEGLLQRVHGGALRKSPALVNYKTRLSQITDQKMTVAKKAAALIQDGMVVFMGGGTTNTQVAGFLAPNLQATIITHNPNAAIALAEHPGVEVILLGGRLYKYAQVTVGAETLEQVRQVRADLCLLGVCSLHPEVGISLQDFEESRIQRAMADNSAEVAALASAEKIGTAAPFVVGGLDLLNYIVTSGDLSEEELAPYRQFHLEIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNP7</accession>
    <name>A0A0N8GNP7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AAA_31 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061956.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78690">
        <property type="protein sequence ID" value="KPL78690"/>
        <property type="gene ID" value="ADN00_05420"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_31" evidence="1">
        <location>
            <begin position="4"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="283" mass="31069" checksum="A35604F71EC6D20F" modified="2016-01-20" version="1">MAITITIANEKGGVGKTTTAVNLAAGLALRLEDQPGALGRVLLIDMDPQGHALLASAFGQHEAPAHQSLAALLTESPPPSAQRFLQHAQHHPNLFLLPGNRNAMVDASRILPSLMANESRLMRAIEPLQSQFAYIIIDTPPTIGDLLVNALVAATDVIIPVETSYLGVSGLRELQKTIEQVRMHFRPDLRVLGYLPTLCDEQRGETHDILNELTSRYPHQVFNPIHKSTDLAYAHSTHMDVFTYRPPRARTSEAIASSSRATQEYAELVEIVLNATWQRVSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNR2</accession>
    <name>A0A0N8GNR2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH luxR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_06200</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062095.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78810">
        <property type="protein sequence ID" value="KPL78810"/>
        <property type="gene ID" value="ADN00_06200"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1741"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041617">
        <property type="entry name" value="TPR_MalT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17874">
        <property type="entry name" value="TPR_MalT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="841"/>
            <end position="906"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="909" mass="102630" checksum="C961F468770B935F" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNZ0</accession>
    <name>A0A0N8GNZ0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_02655</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000012">
        <property type="protein sequence ID" value="KPL79434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79434">
        <property type="protein sequence ID" value="KPL79434"/>
        <property type="gene ID" value="ADN00_02655"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="107" mass="12147" checksum="F699A53DE7CD9CA8" modified="2016-01-20" version="1">MFLKFSRDVHGLSSLQISNDFEHLKALLLWAGSQPLSSAHAFNTNLPDSLFQIGEKGLDQTELQSILNTNQRFLLWGKAMFPVEFQNIRLSWIMKITGISKGKEVII</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WMN9</accession>
    <name>A0A0P6WMN9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Pseudouridine-5'-phosphate glycosidase</fullName>
            <shortName evidence="6">PsiMP glycosidase</shortName>
            <ecNumber evidence="6">4.2.1.70</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">psuG</name>
        <name evidence="7" type="ORF">ADN00_18560</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the reversible cleavage of pseudouridine 5'-phosphate (PsiMP) to ribose 5-phosphate and uracil. Functions biologically in the cleavage direction, as part of a pseudouridine degradation pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>D-ribose 5-phosphate + uracil = H2O + psi-UMP</text>
            <dbReference type="Rhea" id="RHEA:18337"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17568"/>
            <dbReference type="ChEBI" id="CHEBI:58380"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="EC" id="4.2.1.70"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="6">Binds 1 Mn(2+) ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the pseudouridine-5'-phosphate glycosidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.70" evidence="6"/>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064537.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18560"/>
    <dbReference type="EnsemblBacteria" id="KPL70057">
        <property type="protein sequence ID" value="KPL70057"/>
        <property type="gene ID" value="ADN00_18560"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3020"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016798">
        <property type="term" value="F:hydrolase activity, acting on glycosyl bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004730">
        <property type="term" value="F:pseudouridylate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046113">
        <property type="term" value="P:nucleobase catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1790.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01876">
        <property type="entry name" value="PsiMP_glycosidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022830">
        <property type="entry name" value="Indigdn_synthA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007342">
        <property type="entry name" value="PsuG"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42909">
        <property type="entry name" value="PTHR42909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04227">
        <property type="entry name" value="Indigoidine_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110581">
        <property type="entry name" value="SSF110581"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 6" id="KW-0464">Manganese</keyword>
    <keyword evidence="1 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="140"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="26"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="6">
        <location>
            <position position="159"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL70057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="310" mass="32443" checksum="B4CC602AC245E043" modified="2016-01-20" version="1">METTPLVIQPAVAAALKNGTPLVALESAVITHGLPYPHNLQLALDMEQEVRQAGALPATIAILDRKVRVGLTGDEVARLADPQQAARKISRRDFGIALARGENGGTTVAGTLIAAHLAGIRVFATGGIGGVHRGAPFDVSADLHELSLHPLVVVCAGAKSILDLPATLEILETQGVPVIGYQTDEFPAFFSRSSGLPVNASVSTPAELAQIAWRQWQMGLPGAILAVVPPPEDSAIPAEQIEAIIQTAVAEAEEKGIRGAAVTPYLLGRVNDLSKGASMRANLALLKNNARVAAQISIELSRLQPTHRAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WQE4</accession>
    <name>A0A0P6WQE4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_15780</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063992.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72273">
        <property type="protein sequence ID" value="KPL72273"/>
        <property type="gene ID" value="ADN00_15780"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="196" mass="22379" checksum="671E186C28EEF205" modified="2016-01-20" version="1">MKTCEYRVGFIATKPESAYNEVDVTKTKFVLDLSGKNKNADVYQSDIVVPEKKYDLVDMYLEIIIPGHPKAEVVRENLQSPEIMALLPRIFKGHSFNFGGGRYNSILNQDAQNAVNELVKELESIPDYYTPWTVEKWMEKVEVTSQASDELLERIAHDCLDEFAMMGDSHVLLGNGNDLLIHLKKKRTKAREILTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WT26</accession>
    <name>A0A0P6WT26_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_15610</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063960.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72243">
        <property type="protein sequence ID" value="KPL72243"/>
        <property type="gene ID" value="ADN00_15610"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="71" mass="8300" checksum="C20DA010CB832A7A" modified="2016-01-20" version="1">MEGRTWTTKEGEVIPLEKLEPDHLINIKHFLERKISEFREMLEICEPDSLRGATIQEGRESEVKSRASFVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WTL0</accession>
    <name>A0A0P6WTL0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_18895</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064598.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18895"/>
    <dbReference type="EnsemblBacteria" id="KPL70111">
        <property type="protein sequence ID" value="KPL70111"/>
        <property type="gene ID" value="ADN00_18895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003796">
        <property type="term" value="F:lysozyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016998">
        <property type="term" value="P:cell wall macromolecule catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002053">
        <property type="entry name" value="Glyco_hydro_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01183">
        <property type="entry name" value="Glyco_hydro_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51904">
        <property type="entry name" value="GLYCOSYL_HYDROL_F25_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="303" mass="35688" checksum="E71A139606C89487" modified="2016-01-20" version="1">MVYPQLPYVFGPDISVWQDDNSTAQMVDFDIMRQAGATFVGIKVSQSTWIDQDFVYNWHNARLKGIPRKAYHFLDWDKTGKEQARTFYGALKNDPPELLAVCDYEKRTNAPGRSKMLDTLYDFMEEQKRLFDLLDRRPKDAIYTGISFWKEFGSTDSYWARYLLWLAFYSTMVPAAPKPWSQWTFWQWGTPAWGRQFGAESKDIDMNYFRGNKAEFCKFFDLQCDEEPIVEEPKIQKMCVNVRSLNLRTIPGKEQSTIIGQAFQDTEVVVLDRQILGEDIWIKVQMEGWMAQQFQGYRYMRDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WTM2</accession>
    <name>A0A0P6WTM2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Methylated-DNA--protein-cysteine methyltransferase</fullName>
            <ecNumber evidence="7">2.1.1.63</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">6-O-methylguanine-DNA methyltransferase</fullName>
            <shortName evidence="7">MGMT</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">O-6-methylguanine-DNA-alkyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ADN00_14770</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>a 4-O-methyl-thymidine in DNA + L-cysteinyl-[protein] = a thymidine in DNA + S-methyl-L-cysteinyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:53428"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:10132"/>
            <dbReference type="Rhea" id="RHEA-COMP:13555"/>
            <dbReference type="Rhea" id="RHEA-COMP:13556"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:82612"/>
            <dbReference type="ChEBI" id="CHEBI:137386"/>
            <dbReference type="ChEBI" id="CHEBI:137387"/>
            <dbReference type="EC" id="2.1.1.63"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 7">
            <text>a 6-O-methyl-2'-deoxyguanosine in DNA + L-cysteinyl-[protein] = a 2'-deoxyguanosine in DNA + S-methyl-L-cysteinyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:24000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:10132"/>
            <dbReference type="Rhea" id="RHEA-COMP:11367"/>
            <dbReference type="Rhea" id="RHEA-COMP:11368"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:82612"/>
            <dbReference type="ChEBI" id="CHEBI:85445"/>
            <dbReference type="ChEBI" id="CHEBI:85448"/>
            <dbReference type="EC" id="2.1.1.63"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="7">This enzyme catalyzes only one turnover and therefore is not strictly catalytic. According to one definition, an enzyme is a biocatalyst that acts repeatedly and over many reaction cycles.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the MGMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.63" evidence="7"/>
    <dbReference type="EMBL" id="LGCL01000035">
        <property type="protein sequence ID" value="KPL73599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14770"/>
    <dbReference type="EnsemblBacteria" id="KPL73599">
        <property type="protein sequence ID" value="KPL73599"/>
        <property type="gene ID" value="ADN00_14770"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2120"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003908">
        <property type="term" value="F:methylated-DNA-[protein]-cysteine S-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006307">
        <property type="term" value="P:DNA dealkylation involved in DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06445">
        <property type="entry name" value="ATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00772">
        <property type="entry name" value="OGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001497">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014048">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036217">
        <property type="entry name" value="MethylDNA_cys_MeTrfase_DNAb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023546">
        <property type="entry name" value="MGMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036631">
        <property type="entry name" value="MGMT_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010916">
        <property type="entry name" value="TonB_box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01035">
        <property type="entry name" value="DNA_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46767">
        <property type="entry name" value="SSF46767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53155">
        <property type="entry name" value="SSF53155"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00589">
        <property type="entry name" value="ogt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00374">
        <property type="entry name" value="MGMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00430">
        <property type="entry name" value="TONB_DEPENDENT_REC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_binding_1" evidence="9">
        <location>
            <begin position="87"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; methyl group acceptor" evidence="7">
        <location>
            <position position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL73599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="172" mass="18006" checksum="97817DF1E0ABE6A1" modified="2016-01-20" version="1">MDKPTPLPFAPSGMLMPSSPLGAILITASPLGLTGLSITANVSETQRAASATARNTLLVEAARQLTAYFDGLLREFTLPIDWSGMPDFQEQVLRCIQHIPYGQTRAYGEIARALGSPTGSRAVGSALAANPIPIILPCHRVVGADNSLRGFSAPGGVSAKAWLLALEGARLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WU38</accession>
    <name>A0A0P6WU38_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_14475</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000034">
        <property type="protein sequence ID" value="KPL73764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063739.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000034.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL73764">
        <property type="protein sequence ID" value="KPL73764"/>
        <property type="gene ID" value="ADN00_14475"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL73764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="223" mass="24315" checksum="A7577954D4108B46" modified="2016-01-20" version="1">MKSGNSTLMYRLKTLRPDQVIFPASMWGLFAVIVVILYGMDSAYQAARAFVGIVLPMIAGILSAYAVLEDPALELQFSMPRPAWRMLAERLGLIFAVTAVCALTYQVYLALIGLSLAPLGGAAGRQLAWLAPTLNLMGLGCLAGLAAAKPVPGAMAVGLVWFSQLIAYGWFLHHPVARYVYLYMGITHPELPELRASQLVISLLGMIFLTGAWALVRQQERYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WY66</accession>
    <name>A0A0P6WY66_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_17005</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064351.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17005"/>
    <dbReference type="EnsemblBacteria" id="KPL71486">
        <property type="protein sequence ID" value="KPL71486"/>
        <property type="gene ID" value="ADN00_17005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00865">
        <property type="entry name" value="PEBP_bact_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008914">
        <property type="entry name" value="PEBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036610">
        <property type="entry name" value="PEBP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005247">
        <property type="entry name" value="YbhB_YbcL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30289">
        <property type="entry name" value="PTHR30289"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01161">
        <property type="entry name" value="PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49777">
        <property type="entry name" value="SSF49777"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00481">
        <property type="entry name" value="TIGR00481"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL71486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="148" mass="16146" checksum="CFAF7AED2EECF5A5" modified="2016-01-20" version="1">MKISSPAFEQNAGIPELYTCKGEDISPPLSWAGVPEGTASLVLIMDDPDAPVGTWDHWILFNLPANTSELAEDAQAYPEGTRLGRNSWKRNEYGGPCPPGGASHRYFFKLYALDMMLNLPEGVGKAQIEAAMQNHILAQAELVGIYKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZ91</accession>
    <name>A0A0P6WZ91_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_16270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064097.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72040">
        <property type="protein sequence ID" value="KPL72040"/>
        <property type="gene ID" value="ADN00_16270"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="208" mass="22359" checksum="CAD4AA73BE278EED" modified="2016-01-20" version="1">MKATRLWVSVMGAWMGLAGIEHGIGEILQGNQAPDGIMIQSWPDSALFQNLSGEPALTVLPNLLYTGLLAVFFSLVFAAWSIFGAHRQRGGWVLMLLAIPMLLFGGGIFPPLLGFLIGAAATRIPAAVRLSRTITGFNRLLANRWPCIFAACCAAWLAVLPDVVVLGHAFGVDHAGVIIIIIAAAFSLLFLSYLSSIEHDRIELSQSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZG7</accession>
    <name>A0A0P6WZG7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hydrogenase formation protein HupD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_15390</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HypD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063922.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15390"/>
    <dbReference type="EnsemblBacteria" id="KPL72208">
        <property type="protein sequence ID" value="KPL72208"/>
        <property type="gene ID" value="ADN00_15390"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.780"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11740">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002780">
        <property type="entry name" value="Hyd_form_HypD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042243">
        <property type="entry name" value="HypD_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042244">
        <property type="entry name" value="HypD_2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30149">
        <property type="entry name" value="PTHR30149"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01924">
        <property type="entry name" value="HypD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005622">
        <property type="entry name" value="Hydrgn_mat_hypD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00075">
        <property type="entry name" value="hypD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL72208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="362" mass="39949" checksum="A015973DB9C14E65" modified="2016-01-20" version="1">MQLTKEFRNADYIKALAEKIRRVTTRPWNIMEICGGQTHSILHYGLDQLLPPEIELVHGPGCPVCVTSLELIDQALAIAARPDVIFTSFGDMLRVPGSHGDLFTVRANGGDVRVIYSPLDAVQIAIKNPDKEVVFFAIGFETTAPPNIASVIQARALDLKNYSVLVSQVCVPPAMHAILSAPQNRVQGFLAAGHVCSVMGYWEYPPIAEQYCIPITVTGFEPLDLLQGIYQTVIQLERGTHIVENAYSRAVTQEGNRAAQAMINQVYQTVDRNWRGIGLIPQSGWGLRDEFSTFDAQKRFDVGHIKTQESDICIAGQILQGLKKPNQCPAFGKQCTPENPLGATMVSSEGACAAYYRYRREN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X1D1</accession>
    <name>A0A0P6X1D1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">VOC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_14845</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000036">
        <property type="protein sequence ID" value="KPL73068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063816.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000036.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14845"/>
    <dbReference type="EnsemblBacteria" id="KPL73068">
        <property type="protein sequence ID" value="KPL73068"/>
        <property type="gene ID" value="ADN00_14845"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="15"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL73068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="174" mass="19516" checksum="98BE65AFBBEC9B9A" modified="2016-01-20" version="1">MIPQPKLPLPFLKNGIAQVALIVSNLEETVDNYSKLFGINEWHFYTYGPPLVKKMTYHGQPVEHRFRVALGYFGPMRVELIEAKEGQTIYQDFIDQHGYGVHHFGVLVEDMQTALSQAAEAGLEMIQDGSGFGLDGDGHYAYLNTENAIGVTIELIERPKHRNPPEKVYPASGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X200</accession>
    <name>A0A0P6X200_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidase_S9 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_11255</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S9C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063111.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11255"/>
    <dbReference type="EnsemblBacteria" id="KPL76534">
        <property type="protein sequence ID" value="KPL76534"/>
        <property type="gene ID" value="ADN00_11255"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.949"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S9" evidence="3">
        <location>
            <begin position="420"/>
            <end position="626"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL76534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="631" mass="69700" checksum="A60DFD27CAB60981" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X2P8</accession>
    <name>A0A0P6X2P8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ApbA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10290</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062915.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10290"/>
    <dbReference type="EnsemblBacteria" id="KPL76964">
        <property type="protein sequence ID" value="KPL76964"/>
        <property type="gene ID" value="ADN00_10290"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013332">
        <property type="entry name" value="KPR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02558">
        <property type="entry name" value="ApbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ApbA" evidence="1">
        <location>
            <begin position="3"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="325" mass="34805" checksum="263452F88E31D47B" modified="2016-01-20" version="1">MKILIIGAGVLGSIYAAKLSQAGRDVTLLARGARLAQLREHGIVLESSYDGAQSVARVKLVETLRPEDEYDLALVMMRQNQAASVLPMLAANTRIPAVAFLMNNADGGRVFRAVLGDERVLLGFAGAGGLRREHVVVVSTGKKGFEGLTILGEARGGITPRLVEIAEVFAGSGLEAQLETDVDAWLKSHLAIVLPLALGIYAANGDVYRAARTRAVRALMVGGIKEGIRGLKRLGVQVTPPKFHFFAAVPDALLVWFLSRMLATRLAEVSLAGHANAARDEMCYLSEQFYALLSSSGVALPAWERLYAFTDEQTALIPDGVKQIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X2S7</accession>
    <name>A0A0P6X2S7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Putative 3-methyladenine DNA glycosylase</fullName>
            <ecNumber evidence="5">3.2.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_10650</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the DNA glycosylase MPG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.-" evidence="5"/>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062979.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10650"/>
    <dbReference type="EnsemblBacteria" id="KPL77019">
        <property type="protein sequence ID" value="KPL77019"/>
        <property type="gene ID" value="ADN00_10650"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2604"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003905">
        <property type="term" value="F:alkylbase DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00540">
        <property type="entry name" value="AAG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00527">
        <property type="entry name" value="3MGH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011034">
        <property type="entry name" value="Formyl_transferase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003180">
        <property type="entry name" value="MPG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036995">
        <property type="entry name" value="MPG_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10429">
        <property type="entry name" value="PTHR10429"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02245">
        <property type="entry name" value="Pur_DNA_glyco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50486">
        <property type="entry name" value="SSF50486"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00567">
        <property type="entry name" value="3mg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4 5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL77019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="202" mass="22503" checksum="E81BE00A99D2AC54" modified="2016-01-20" version="1">MSSTDLLDQSFYDRHAVTVARDLLGRRLVRRLNGQRVSGYIIECEAYYGEEDLACHARAGRTPRTAVMYGQPGRAYVYFTYGMHWLLNCVTGAEGLAAAVLLRAIWPQEGLEQIAARRPGVARARWCDGPAKLCRALQIDGQQNGASLLSAGGELWIEHGLPLPDEWVQTSPRIGIQSTPEPWRSIPWRFVATPPPNFWPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X332</accession>
    <name>A0A0P6X332_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_14090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14090"/>
    <dbReference type="EnsemblBacteria" id="KPL74152">
        <property type="protein sequence ID" value="KPL74152"/>
        <property type="gene ID" value="ADN00_14090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008253">
        <property type="term" value="F:5'-nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011951">
        <property type="entry name" value="HAD-SF_hydro_IA_YjjG/PynA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02254">
        <property type="entry name" value="YjjG/YfnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL74152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="231" mass="25998" checksum="BCB2DCD4A9DE0D82" modified="2016-01-20" version="1">MPYQWLLFDADGTLFDYDAAEASALREAFRLERLSFSTEIEAAYRQINARVWQAFENGQISSQELRVERFRQLFQQFNLNEDAQIFSRLYLGFLGQSSQLLDGAEELIFGLRGQGYRLAIITNGLSDVQRPRLAASSISGCFEGLFISEELPAAKPHPAFFDAVFQQIGQPQKSSVLVIGDSLSSDIRGGQAYQLDTCWYHPNGGAPLPDDLQPTYTITRLEELLDILQSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X338</accession>
    <name>A0A0P6X338_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_12850</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063421.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000027.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL75525">
        <property type="protein sequence ID" value="KPL75525"/>
        <property type="gene ID" value="ADN00_12850"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL75525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="142" mass="16267" checksum="7B2371FF86580917" modified="2016-01-20" version="1">MPRFSDWLTEKYTSWENTQGSTQTYAKYATYLCVDAKVLVNIMLGKALPNTGDLMAIAAKEGLEVYDVLEKDRPEEGVIEVFSSLGTMPTDFRMRMAHAIYEAEETVKGRNISTESDEAKQVFIEAFERWGFHYQGNFEKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X3H6</accession>
    <name>A0A0P6X3H6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FHA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13720</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063594.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000032.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13720"/>
    <dbReference type="EnsemblBacteria" id="KPL74353">
        <property type="protein sequence ID" value="KPL74353"/>
        <property type="gene ID" value="ADN00_13720"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00060">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000253">
        <property type="entry name" value="FHA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026870">
        <property type="entry name" value="Zinc_ribbon_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00498">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13240">
        <property type="entry name" value="zinc_ribbon_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00240">
        <property type="entry name" value="FHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50006">
        <property type="entry name" value="FHA_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FHA" evidence="1">
        <location>
            <begin position="88"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="176" mass="19259" checksum="D27A9136D9969798" modified="2016-01-20" version="1">MVICPKCHTEQPDGALFCNECGAQLVSLDAFEFKTLNSEDSPELFTSPLTDLPDVELEDDISMMAQSEVSLLLLDSGKMIHLSGKREFSLGRVAEGQLILPDIDLSPYDAYSQGVSRLHASIKISPRIIILSDLGSSNGTRVNGQRIGPHIDYPINHGDLVALGKLRIKILIDQKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X463</accession>
    <name>A0A0P6X463_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_08180</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062498.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08180"/>
    <dbReference type="EnsemblBacteria" id="KPL77851">
        <property type="protein sequence ID" value="KPL77851"/>
        <property type="gene ID" value="ADN00_08180"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.637"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024671">
        <property type="entry name" value="Atg22-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11700">
        <property type="entry name" value="ATG22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="84"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="108"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="241"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="268"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="303"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="327"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="361"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="389"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="1"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL77851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="436" mass="47745" checksum="312148F3F1692366" modified="2016-01-20" version="1">MSEKEHKRAITSWTLYDWANSTFATTIAAAVLPVYYSTVASSNLEPNVATSNWAFTTSIALILVAILGPILGAMADFSGAKKKFLTAFVLAGVTGTALLFFVRSGDWLMASLFFIIGNVGFAGANVFYDSLLPHIARPEEIDQVSSRGYAMGYLGGGLLLAVNLGMIMFTPDSQTELMTRLSFLSVAVWWLIFTIPLWKYVPEPTRRILEGEKGSNPFQASFGRLAHTFSEIQKYKQLSKFIAAFWLYNNGIGTIIYMASIYGAELQFSTTTIIGTLLMVQFVAIPFAYLFGWLAKKLGTKRSILLSLFIYTLIAIGGYFLTKEIHFWILGFAVATVQGGSQALSRSLCGRMMPKSKSAEFYSFFSISEKIAGTVGPLLFGLVSRLMGGSRLSIVSLIIFFAAGGLLLTRVDEKEAIAVAEVEEDKFMQLSTEAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X579</accession>
    <name>A0A0P6X579_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">PLDc_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_10450</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062944.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76988">
        <property type="protein sequence ID" value="KPL76988"/>
        <property type="gene ID" value="ADN00_10450"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027379">
        <property type="entry name" value="CLS_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13396">
        <property type="entry name" value="PLDc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="PLDc_N" evidence="7">
        <location>
            <begin position="24"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL76988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="71" mass="7680" checksum="4EDA5C417F35DC4E" modified="2016-01-20" version="1">MMARAGFVFANVLFFMLMLIWPVLSLAALFVLRGKPIKDTARALWALVITAIPLLGALAFFIAADEPDSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5A2</accession>
    <name>A0A0P6X5A2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Osmotically inducible protein OsmC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_18695</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064558.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70077">
        <property type="protein sequence ID" value="KPL70077"/>
        <property type="gene ID" value="ADN00_18695"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003718">
        <property type="entry name" value="OsmC/Ohr_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036102">
        <property type="entry name" value="OsmC/Ohrsf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02566">
        <property type="entry name" value="OsmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82784">
        <property type="entry name" value="SSF82784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="138" mass="15065" checksum="209B620B0DD68681" modified="2016-01-20" version="1">MEGKVTWRQGMSFTGEAASGWRIPIGTSRDHGGHDDGAAPMELMAMGLASCSGMDVISILKKKQQAVTDFEVKFQIERAKDHPKVFTHIVLEYVVTGHSVDPAAVERAVELSTTKYCPGYAMMKQVVPIEVKISVLEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5B1</accession>
    <name>A0A0P6X5B1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">N6_N4_Mtase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_18760</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the N(4)/N(6)-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064570.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="REBASE" id="132901">
        <property type="entry name" value="M.OapP3M1ORF18760P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70086">
        <property type="protein sequence ID" value="KPL70086"/>
        <property type="gene ID" value="ADN00_18760"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3061"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006306">
        <property type="term" value="P:DNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002941">
        <property type="entry name" value="DNA_methylase_N4/N6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002295">
        <property type="entry name" value="N4/N6-MTase_EcoPI_Mod-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01555">
        <property type="entry name" value="N6_N4_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015855">
        <property type="entry name" value="TypeIII_Mtase_mKpnI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00506">
        <property type="entry name" value="D21N6MTFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N6_N4_Mtase" evidence="4">
        <location>
            <begin position="113"/>
            <end position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL70086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="617" mass="70265" checksum="86A53DF27AB2C763" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5V1</accession>
    <name>A0A0P6X5V1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_12840</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL75524">
        <property type="protein sequence ID" value="KPL75524"/>
        <property type="gene ID" value="ADN00_12840"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL75524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="145" mass="16167" checksum="8A0519F69CE5C495" modified="2016-01-20" version="1">MHKNHQSHSKGMYHELGNLREEIRKFADTLQLFESDIEFPGAEETIETLRGISMGAFSCAELLALALKQSGQSCQAVSPRRITLQDQVKENVEKTLHCCAKLSTSLRSLKQILRTIPVAELGGMEQASQRVQAALSNIATEWEDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X6G9</accession>
    <name>A0A0P6X6G9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_05245</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78664.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061923.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78664">
        <property type="protein sequence ID" value="KPL78664"/>
        <property type="gene ID" value="ADN00_05245"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1523"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004332">
        <property type="term" value="F:fructose-bisphosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00958">
        <property type="entry name" value="DhnA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002915">
        <property type="entry name" value="DeoC/FbaB/LacD_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041720">
        <property type="entry name" value="FbaB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01791">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038992">
        <property type="entry name" value="Aldolase_Ia"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01133">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78664.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="252" mass="27397" checksum="F3786044F576ADCC" modified="2016-01-20" version="1">MSEIGKQVRLNQIFNPVSGNSVMVAMDHAVVVGPVKGIEDPRKTVDQLCKEQPDTIFMPIGAIKRVLPSLIKYKIPFIASIDTCTFLGPEPDYFFLADTVEHALSVGASAVSMHVFVGPQKTSEMLKGLGKIAGDCDRLGMPLMAIMYPEGFENNFDVHHVKWVARIASELGADIVKTYYTGSKETFQEVVESCPIPVLLSGGEVTSDPNDFLAILKDSIAAGGKGCAVGRNVWQREDPATMLRKVMKTVHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X772</accession>
    <name>A0A0P6X772_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplE</name>
        <name evidence="9" type="ORF">ADN00_12540</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">This is 1 of the proteins that binds and probably mediates the attachment of the 5S RNA into the large ribosomal subunit, where it forms part of the central protuberance. In the 70S ribosome it contacts protein S13 of the 30S subunit (bridge B1b), connecting the 2 subunits; this bridge is implicated in subunit movement. Contacts the P site tRNA; the 5S rRNA and some of its associated proteins might help stabilize positioning of ribosome-bound tRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA and the P site tRNA. Forms a bridge to the 30S subunit in the 70S ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uL5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063358.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12540"/>
    <dbReference type="EnsemblBacteria" id="KPL76155">
        <property type="protein sequence ID" value="KPL76155"/>
        <property type="gene ID" value="ADN00_12540"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3989"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01333_B">
        <property type="entry name" value="Ribosomal_L5_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002132">
        <property type="entry name" value="Ribosomal_L5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020930">
        <property type="entry name" value="Ribosomal_L5_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031309">
        <property type="entry name" value="Ribosomal_L5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022803">
        <property type="entry name" value="Ribosomal_L5_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031310">
        <property type="entry name" value="Ribosomal_L5_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11994">
        <property type="entry name" value="PTHR11994"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00281">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00673">
        <property type="entry name" value="Ribosomal_L5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002161">
        <property type="entry name" value="Ribosomal_L5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55282">
        <property type="entry name" value="SSF55282"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L5" evidence="7">
        <location>
            <begin position="24"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L5_C" evidence="8">
        <location>
            <begin position="85"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL76155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="180" mass="20211" checksum="6DC108912EECF755" modified="2016-01-20" version="1">MNNMKQQYVKEVVPALKKGLNLENINEVPRIQKVVVNIGLGEALDNPKALEAAAGDLTTITGQKPIIIKARKSIANFKLREGRLIGAKVTLRGDRMWSFLDRLVNIALPRVRDFRGVSSDAFDGRGNYTLGLREQLIFPEIQYDKIDKIRGMEVTIVTTATTDDQAYLLLKLLGMPFRKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X880</accession>
    <name>A0A0P6X880_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_05005</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061855.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79204">
        <property type="protein sequence ID" value="KPL79204"/>
        <property type="gene ID" value="ADN00_05005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="388" mass="43757" checksum="2CA1F42FE8DE2F06" modified="2016-01-20" version="1">MTAKTKKQPYILIILWLLLGACLFGLAGSSYSNLCLPQASRGQERLSAEQQALMAEAQHLRASLGGTVWPGWDAAPIPLIAFNESRVFLTGATEPPADGWVSVPREQQRGGAWSRVDEEIEALGQPYYRQTLPDPQITPQNFTVKVGEAWAASLMTKEASDISLVDEFRQQMPPVLRAVIPFGLAIRLFNSDWYISALLHESFHAYQGQNAPQRLYAAEFALNNHENDYPFEDEAAWQAELQALQDALRAKTDEEAARHAQTFLTLRAQRRAALQLTAEQIDLERQREWLEGSAKYTELAIWQAAARDEQYAPIAATSLLRDFQQYRGFNGRWQNEVGQITRSAGSETLFYYSGMAQAFLLDRLAPNWKESYFLPDIWLEELLAGALQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X8A4</accession>
    <name>A0A0P6X8A4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Flagellar motor switch protein FliG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">ADN00_17055</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Bacterial flagellum basal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FliG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064257.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17055"/>
    <dbReference type="EnsemblBacteria" id="KPL71403">
        <property type="protein sequence ID" value="KPL71403"/>
        <property type="gene ID" value="ADN00_17055"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.473"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000090">
        <property type="entry name" value="Flg_Motor_Flig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023087">
        <property type="entry name" value="Flg_Motor_Flig_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011002">
        <property type="entry name" value="FliG_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032779">
        <property type="entry name" value="FliG_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028263">
        <property type="entry name" value="FliG_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30534">
        <property type="entry name" value="PTHR30534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01706">
        <property type="entry name" value="FliG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14841">
        <property type="entry name" value="FliG_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14842">
        <property type="entry name" value="FliG_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003161">
        <property type="entry name" value="FliG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00954">
        <property type="entry name" value="FLGMOTORFLIG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48029">
        <property type="entry name" value="SSF48029"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00207">
        <property type="entry name" value="fliG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="7" id="KW-0283">Flagellar rotation</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FliG_N" evidence="12">
        <location>
            <begin position="8"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="FliG_M" evidence="11">
        <location>
            <begin position="118"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="domain" description="FliG_C" evidence="10">
        <location>
            <begin position="221"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF14841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF14842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KPL71403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="339" mass="37535" checksum="DA2F1B0019408C44" modified="2016-01-20" version="1">MANSDVILSGLEKTSVLLLSLGVEASSKILQYLNEGEMERVLLSLSKTSSVPPEMRRAILQEAFSLTQIDFGVHAGGIEYSRQILARAVGPRRGADILERISAHQQLSSFEMLRNADPSQVAQLLQDELPQTIALVLSYLEAKVAADILTNFPKELQIEVTLRLAVMDRVSPQVVQVVEHVLKNKLSGVLSEVDFRSTGGVSFLVKMLNQVDRGVQKSILESLETTNPKLVEEIRSNMFTFDDLAKLDDRTMQRILRDVSKADLALALKAASEKLKDVVYRNLSERARDNLQEEIEVLGPQLAKNVYGAQRRIVDAVRVLEESGEIVLGGGGEEYELIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X8A8</accession>
    <name>A0A0P6X8A8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Deoxyribose-phosphate aldolase</fullName>
            <shortName evidence="3">DERA</shortName>
            <ecNumber evidence="3">4.1.2.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">2-deoxy-D-ribose 5-phosphate aldolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Phosphodeoxyriboaldolase</fullName>
            <shortName evidence="3">Deoxyriboaldolase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">deoC</name>
        <name evidence="4" type="ORF">ADN00_03955</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>2-deoxy-D-ribose 5-phosphate = acetaldehyde + D-glyceraldehyde 3-phosphate</text>
            <dbReference type="Rhea" id="RHEA:12821"/>
            <dbReference type="ChEBI" id="CHEBI:15343"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="ChEBI" id="CHEBI:62877"/>
            <dbReference type="EC" id="4.1.2.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.4" evidence="3"/>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03955"/>
    <dbReference type="EnsemblBacteria" id="KPL79231">
        <property type="protein sequence ID" value="KPL79231"/>
        <property type="gene ID" value="ADN00_03955"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.146"/>
    <dbReference type="UniPathway" id="UPA00002">
        <property type="reaction ID" value="UER00468"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004139">
        <property type="term" value="F:deoxyribose-phosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009264">
        <property type="term" value="P:deoxyribonucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046386">
        <property type="term" value="P:deoxyribose phosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00959">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00114">
        <property type="entry name" value="DeoC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011343">
        <property type="entry name" value="DeoC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002915">
        <property type="entry name" value="DeoC/FbaB/LacD_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028581">
        <property type="entry name" value="DeoC_typeI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10889">
        <property type="entry name" value="PTHR10889"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10889:SF1">
        <property type="entry name" value="PTHR10889:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01791">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001357">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01133">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00126">
        <property type="entry name" value="deoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0704">Schiff base</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with acetaldehyde" evidence="3">
        <location>
            <position position="179"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL79231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="244" mass="26283" checksum="6F293153EC79DE20" modified="2016-01-20" version="1">MKEMVEQAKAYLVQLPELPEMKPVSNDQVASLIDHTILKPEATPEQVEKLCLEAREYSFAAVCVNPIFIPQVARLLKGSPAKACSVIGFPLGASLTRIKVEETRIVIEEGAQEVDMVLSIGLLKAREYEQVYEDILAVTQACHQHNVALKVIFENCLLEKEEKIMACLLSQSAGVDFVKTSTGFSKAGATVEDIDLMRRVVGPAMGVKAAGGVRSLADAQAMLKAGANRLGTSAGLTIVKEALS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X8E8</accession>
    <name>A0A0P6X8E8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">ADN00_17330</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17330"/>
    <dbReference type="EnsemblBacteria" id="KPL71448">
        <property type="protein sequence ID" value="KPL71448"/>
        <property type="gene ID" value="ADN00_17330"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.529"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033479">
        <property type="entry name" value="dCache_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029151">
        <property type="entry name" value="Sensor-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02743">
        <property type="entry name" value="dCache_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103190">
        <property type="entry name" value="SSF103190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0807">Transducer</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="24"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="299"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="11">
        <location>
            <begin position="320"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="10">
        <location>
            <begin position="458"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="504"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KPL71448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="773" mass="81818" checksum="E7CB12F8EE107A35" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAD3</accession>
    <name>A0A0P6XAD3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_16315</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16315"/>
    <dbReference type="EnsemblBacteria" id="KPL72116">
        <property type="protein sequence ID" value="KPL72116"/>
        <property type="gene ID" value="ADN00_16315"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="584"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="5">
        <location>
            <begin position="825"/>
            <end position="937"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="5">
        <location>
            <begin position="948"/>
            <end position="1066"/>
        </location>
    </feature>
    <feature type="domain" description="HTH araC/xylS-type" evidence="3">
        <location>
            <begin position="1082"/>
            <end position="1180"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="876"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="999"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL72116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="1184" mass="132475" checksum="5EF401CBE24BCEBD" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAM0</accession>
    <name>A0A0P6XAM0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_04760</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061810.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04760"/>
    <dbReference type="EnsemblBacteria" id="KPL79164">
        <property type="protein sequence ID" value="KPL79164"/>
        <property type="gene ID" value="ADN00_04760"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.316"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003737">
        <property type="entry name" value="GlcNAc_PI_deacetylase-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024078">
        <property type="entry name" value="LmbE-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12993">
        <property type="entry name" value="PTHR12993"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02585">
        <property type="entry name" value="PIG-L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102588">
        <property type="entry name" value="SSF102588"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="291" mass="32253" checksum="79A09F2D5421F8C5" modified="2016-01-20" version="1">MQEQKNSKKIILASLAHPDDESFGMGGTLALYARQGADVHLVCGTRGEAGDVDPVYMNGFHSVAEVRMHELSCAANALGLASVEYLGYRDSGMPGSPDNRHPHALVAQPTEEVALKIVYHIRKLRPQVVLTFDPIGGYRHPDHIAMHLATVQAFDLAADPQVRVEENLPPYKPQKLLFHVIPRGYLRAAVRLMRLLGQDPSRYGRNKDIDLTALANVNFPVHVAINYQRVARQQEDAAACHASQGGQQNRNSLVRILQRMMNSKVDRFMQAYPTPPDGYLAKDLFDGVSVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAQ3</accession>
    <name>A0A0P6XAQ3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AAA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_15620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063961.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15620"/>
    <dbReference type="EnsemblBacteria" id="KPL72244">
        <property type="protein sequence ID" value="KPL72244"/>
        <property type="gene ID" value="ADN00_15620"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.827"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="277"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="524" mass="57718" checksum="86442F86BAAE2DF9" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAR0</accession>
    <name>A0A0P6XAR0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">VanZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_09255</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09255"/>
    <dbReference type="EnsemblBacteria" id="KPL77307">
        <property type="protein sequence ID" value="KPL77307"/>
        <property type="gene ID" value="ADN00_09255"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006976">
        <property type="entry name" value="VanZ-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04892">
        <property type="entry name" value="VanZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="VanZ" evidence="2">
        <location>
            <begin position="27"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="150" mass="16406" checksum="30C5599F40B7ECFD" modified="2016-01-20" version="1">MRHPPFKLCDFTDMRKWQTILNRWGPVLLVMAAIFAFSSLPGEKAEAVLVGLVGTTESAPIEALPQMVIDWYKVGHVIGYALLGAAAARALALSGRAGFWPALLICAAYAVTDEFHQHFTPNRSGRALDVLIDAGAAAVAIYLYLFFRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBR1</accession>
    <name>A0A0P6XBR1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_15280</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063904.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15280"/>
    <dbReference type="EnsemblBacteria" id="KPL72192">
        <property type="protein sequence ID" value="KPL72192"/>
        <property type="gene ID" value="ADN00_15280"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="176" mass="19931" checksum="7B223DB11064C69D" modified="2016-01-20" version="1">MSDLFDQVTSDQDIFKKLLSKVPGFKGYIERENRRSSDKLLRGMVAERYEEQWGRISGLQRDLISEGGLVYIDDLESAAIKLRQFIDRVKTATYGYAGLFDAVKVREDELQKMYQYDLSLLDGAEEVKRAVDNVEASMGSEGLPASIRHLTSLAQNMVELFNRRAEVITQGEEPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBU0</accession>
    <name>A0A0P6XBU0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_08860</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062639.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77246">
        <property type="protein sequence ID" value="KPL77246"/>
        <property type="gene ID" value="ADN00_08860"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL77246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="72" mass="7885" checksum="8457F975E559AE3D" modified="2016-01-20" version="1">MDIVNIGSVQFKDRMSGELSYIVVRVVDNSIGIGISEESSGDAEVFFDTEKCELIIEWLSTALATARTISAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBU8</accession>
    <name>A0A0P6XBU8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_08935</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77255">
        <property type="protein sequence ID" value="KPL77255"/>
        <property type="gene ID" value="ADN00_08935"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL77255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="264" mass="30140" checksum="2BE360C0CCCCEB89" modified="2016-01-20" version="1">MAYTDCMGPYPLFSCEDWEKVPGEISNLDSDLVAVSMVTDPFADFDLEKMQACFDSRFFPFKQHYAVDLDIPLEQIGGKRRRRHARRALNKLTIAVSESPAEYLDEWMDLYAVLMEKHQIKGVRAFSRVSFLEQFQIPGAVMIRALYHGKAVGIQVYLYQGNVVHAHLGACSPEGYDLEATYAIDYYSFEYFKGKARWVNLGGGVGISDEELDGLSIYKSAWASHTRTSYFCGKVLNAERYEELMRIKNGPQTNYFPAYRAGEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBX8</accession>
    <name>A0A0P6XBX8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SufBD_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_15350</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0051 (ycf24) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15350"/>
    <dbReference type="EnsemblBacteria" id="KPL72293">
        <property type="protein sequence ID" value="KPL72293"/>
        <property type="gene ID" value="ADN00_15350"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.772"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000825">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037284">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011542">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045595">
        <property type="entry name" value="SufBD_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43575">
        <property type="entry name" value="PTHR43575"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01458">
        <property type="entry name" value="SUFBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19295">
        <property type="entry name" value="SufBD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101960">
        <property type="entry name" value="SSF101960"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01981">
        <property type="entry name" value="sufD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SufBD_N" evidence="3">
        <location>
            <begin position="21"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL72293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="446" mass="49660" checksum="297DE5C2C6C0B697" modified="2016-01-20" version="1">MKVVSRSRSRGEQKQEWSFRKEDVRDSGSALIDAYRNEAWKIFNNLEMPDRTNEAWRRTDIRGLAVNRFSLPAQGAFTHLEQPPQRLLESVTGESHGGQVLLYAGGAETRLDETVKAQGVIFCDLLTAEREYPDLLGKAMGKVIGAGEGKFAALSGSLAQMGVFLYVPKNVVVENPLHSLLWGPGIDLAYVSHIVVYLEEGASVTYVHEAASPTYETGQTLHSGLFEVHVGRGANLRLVELQSWGEHVWNFSHERVEVEADANLDWIFGAVGSRLTKNFSDLNLIGRGATGKMSGFFFTDHEQHLDHDTQQNHMAPHTTSDLLFKGALLGHSRSVWQGMIYVSPDATKTDGYQANRNLVLSPNARADSIPGLEIKTDDVRCTHGATVGQIDPEPVFYLMSRGISKRDAERLIVEGFFDPIMQRIPFEGVRQRFQTAIQDKMQSYGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XCD8</accession>
    <name>A0A0P6XCD8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Stage V sporulation protein S</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_01605</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061212.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80566">
        <property type="protein sequence ID" value="KPL80566"/>
        <property type="gene ID" value="ADN00_01605"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036882">
        <property type="entry name" value="Alba-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007347">
        <property type="entry name" value="SpoVS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35331">
        <property type="entry name" value="PTHR35331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04232">
        <property type="entry name" value="SpoVS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL80566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="86" mass="9088" checksum="40E7B3315F8954D8" modified="2016-01-20" version="1">MDVIKVKANSRTAAVAGAIAGVMREHKYAEVQAIGAGAVNQAIKALVLAKGYLAEDGIPIICMPEFVDVDIDGKVRTAIKLIIEPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDB2</accession>
    <name>A0A0P6XDB2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_07130</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062292.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78239">
        <property type="protein sequence ID" value="KPL78239"/>
        <property type="gene ID" value="ADN00_07130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13579">
        <property type="entry name" value="Glyco_trans_4_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="31"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="172"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="360" mass="40425" checksum="94F5E7A0DF9F5379" modified="2016-01-20" version="1">MRIGLMIYGELANLSGGYIYDRQLVDYLTAQGDVVEVISMPWRDYPLRLLENLDRKLIQRLANLEVDVLLQDELNHPSLFLVNRWIKKQACYPIVSIVHHLRSNEVHSTLEHWVYQRVERAYLKSVDAFVYNSRTTSVAVQALMGGPTRHVIAYPGGDRLGKGIRLEEISQRAHTPGPLRIVFLGNLIPRKGLHTLLHAVASIKETNWTLDVIGRLDADPLYSGEMQHLSRTLGLTKRVLFRGQVDDGDVMETLRTSHLMVVPSSYEGFGIIYLEAMGYGVIPVATTAGAASEIIQHGENGYLIQPDNQGALASLIEGLAENRHRLEQVSLAARAHFDAFPTWQTGAEKIRQFLQALSEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDN9</accession>
    <name>A0A0P6XDN9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Heat shock protein 70 family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_00850</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the heat shock protein 70 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061055.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00850"/>
    <dbReference type="EnsemblBacteria" id="KPL81105">
        <property type="protein sequence ID" value="KPL81105"/>
        <property type="gene ID" value="ADN00_00850"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.34.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018181">
        <property type="entry name" value="Heat_shock_70_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029047">
        <property type="entry name" value="HSP70_peptide-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013126">
        <property type="entry name" value="Hsp_70_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19375">
        <property type="entry name" value="PTHR19375"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00012">
        <property type="entry name" value="HSP70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100920">
        <property type="entry name" value="SSF100920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00329">
        <property type="entry name" value="HSP70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01036">
        <property type="entry name" value="HSP70_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0346">Stress response</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL81105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="529" mass="58662" checksum="83B330B8CC4BFDE0" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDR0</accession>
    <name>A0A0P6XDR0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Bac_transf domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_00520</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial sugar transferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00520"/>
    <dbReference type="EnsemblBacteria" id="KPL81142">
        <property type="protein sequence ID" value="KPL81142"/>
        <property type="gene ID" value="ADN00_00520"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3498"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003362">
        <property type="entry name" value="Bact_transf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017475">
        <property type="entry name" value="EPS_sugar_tfrase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02397">
        <property type="entry name" value="Bac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03025">
        <property type="entry name" value="EPS_sugtrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="16"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="58"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="296"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="Bac_transf" evidence="8">
        <location>
            <begin position="291"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL81142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="484" mass="55442" checksum="CA8B8B2FEB24EA94" modified="2016-01-20" version="1">MTSGALRLPRRTQWRAFTIFLITSDIIMLVLAFQAAYFVRFELNLQIFNLWVVPSLTFYRIFMVCLIPVWLAIFAIKGLYNRAYLLGGTEEYSRLFNGSTIGAFVVIIASFVSTELYLARAWLFLSWAFSFLFIGFGRFVLRRLVYYLRGYGYFLSPAVILGANDEGLLLAEQLLQWKTSGFDIKGFIDKKIKPGTIVWRNLRCLGDLNQIDEVLNTFEIEELILASSAISSRDKMVEIFKRYGVNSKVNVRLSSGLYEIVTTGLTVNQFAYVPLVGVNPVRLTGMDKALKMALDYLITIPGIIAISPLLLLIAIIIRLDSEGPIIHRRRVVGVNGVKFDAFKFRTMHVNGDAILASRPDLQEELATNHKLKDDPRITRVGKYLRKFSLDELPQLFNVLRGEMSLVGPRMITEQEMQKYDKWDLNLLTVRPGMTGLWQVSGRSNISYEERVRLDMYYIRNWAIWLDLQLLMQTIPAVIRSIGAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XEJ1</accession>
    <name>A0A0P6XEJ1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_07835</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000020">
        <property type="protein sequence ID" value="KPL78078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062434.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000020.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78078">
        <property type="protein sequence ID" value="KPL78078"/>
        <property type="gene ID" value="ADN00_07835"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="214" mass="24952" checksum="F2E3DAF0B7403494" modified="2016-01-20" version="1">MTHTNAIFANLDMWRNLPAYQLERRADIFFSIYLPEILFYKFGVNIEGIIPEFPIRVGTIDHDIDINKSFKVDYLAKASDSKTIILIELKTDVSSRRDKQDWYLDRAKQVGLVELLDGVRKIYKATNSKKKYEFLLGMLQNLEFIAFDKNKSFEITQADYDIKIAYIQPNNPKGQENVITFQEISEIIERHGDELSLRFSKSLLKWAETKAGEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XEZ3</accession>
    <name>A0A0P6XEZ3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NB-ARC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_14325</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000034">
        <property type="protein sequence ID" value="KPL73743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063714.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000034.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14325"/>
    <dbReference type="EnsemblBacteria" id="KPL73743">
        <property type="protein sequence ID" value="KPL73743"/>
        <property type="gene ID" value="ADN00_14325"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002182">
        <property type="entry name" value="NB-ARC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00931">
        <property type="entry name" value="NB-ARC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NB-ARC" evidence="1">
        <location>
            <begin position="177"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL73743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="503" mass="56153" checksum="4838DB5D6C1832D2" modified="2016-01-20" version="1">MDLAEISPSSIEASLKALRSGNPPHGGLFALVEGIRSPEEKRLVIEDLLINTITDTYLQMRKVEGLKSALPANRQQTLAQIFEDFSTKNSDLQAWCCLYYRYLSPIDLSVEEISQAACVVPQHLRRRINQGLALLTQTLRRRALQNHSQVAAVTQHLPTPEYTQLVGVQSYTSLLLRLFKDPEGPRMVSLEGMGGIGKTAVARAFVSLPENVALWQKVLWVSARQTLLAEDGQLTRSPDASATLEDISARLAEQMGLAALAGKPVQERLEGLRAALFQNRCLVVVDNLETIEEYQQLIPALARMAGSSRFLITTRQTLRQYPFVHTLPIQELPVQSAYELISAEMTRRGQPGSLASRDFAELYRVIGGLPLAIKLVAAQLKLHSLNEILAGFRSAQAGTDGLYRFLYWKTWQSLREPAKQLLLSFLAANPEGEDLEFLSIMSGQSQQDFYTAMQELDAFSLLETNTDHEPTLYRLHRLTVTFLQTDILNLWSGDSTDERTQSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XF02</accession>
    <name>A0A0P6XF02_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">L-iditol 2-dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_14385</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000034">
        <property type="protein sequence ID" value="KPL73752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063723.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000034.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14385"/>
    <dbReference type="EnsemblBacteria" id="KPL73752">
        <property type="protein sequence ID" value="KPL73752"/>
        <property type="gene ID" value="ADN00_14385"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1396"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="PKS_ER" evidence="3">
        <location>
            <begin position="8"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL73752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="353" mass="38693" checksum="6751D5F385109FB2" modified="2016-01-20" version="1">MKAARYYGFKDVRVEEIPVPEVPAGFVRVRVAWAGICGTDRHEYTGPVWIPMEKPHRITGQMAPITLGHELSGVIVALGEGVSGWQVGDRITASGNIYCGECDLCKSGRVNLCENLAFNGIGRDGAFAEYMVLPAYQLFRVPDSVSLEQAVLAEPLACGWHATRLLGDVKGKNVAVVGPGIIGLACVFAAKQAGAEQIMVVGLGRDNEELARLVGATHYVDSRDMNPVEEGRKLTGKPGFDVVYECVGVQSSLNTASELLRKSAKLMVMGVFEKMPQFNMNIFQEGERVLYTSQAYTDELRDILEVMEKQTIPVEKLITARIPLERIVEDGFEELLRNPSKHVKIAVQIKAVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XF54</accession>
    <name>A0A0P6XF54_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Probable membrane transporter protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_07330</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062329.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07330"/>
    <dbReference type="EnsemblBacteria" id="KPL78270">
        <property type="protein sequence ID" value="KPL78270"/>
        <property type="gene ID" value="ADN00_07330"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002781">
        <property type="entry name" value="TM_pro_TauE-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01925">
        <property type="entry name" value="TauE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="39"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="104"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="173"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="224"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL78270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="246" mass="26118" checksum="4A1012C149A0A8AE" modified="2016-01-20" version="1">MDWTVIGFILVGFIAQMIDGSLGMAYGVSANSFLLNLGILPATASASVHLSEVITTAISGYSHWKLGNVVRQRLIRLAVPGVLGGVLGAYILTHLNGEVIKPYISAYLLLMGGQIVLRAIRNTPHHEKESRLAFLGFIGGLMDAIGGGGWGPIVTTTMIARGNEPRKVIGTVNLSEFFVTFAQAVTFVALLKELRWDLVLGLAAGGVLAAPLGARLVQVVKPRVMMAMVGLLIIGLSLNTILQSIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XG69</accession>
    <name>A0A0P6XG69_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_04810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061820.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79172">
        <property type="protein sequence ID" value="KPL79172"/>
        <property type="gene ID" value="ADN00_04810"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="235" mass="26000" checksum="91219A1EEC1AD797" modified="2016-01-20" version="1">MPSLGSILILALVFVTVGFIGGALVAIAWSNREKTEEKEEPPARKIPSRLEPILELFRLRTNQQLVVFIDEKYYTKSSEMEESLKSELRGLAEDWLRWLGVERPTQPVAPELQAPPAIDIARESEARLNGIVGISTEEPPSAAPQAGSAPVMAAELGQELRPRPTTIVGQINEILQEKLAGTNKTISLADDMHRGVIVWVGIEKFDGIDAVPYPDAQKLIREAVKEWEQRNESAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGA8</accession>
    <name>A0A0P6XGA8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_18935</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064606.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70118">
        <property type="protein sequence ID" value="KPL70118"/>
        <property type="gene ID" value="ADN00_18935"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="328" mass="35514" checksum="3B89175EEB170C20" modified="2016-01-20" version="1">MAERSSIFQTVQIGVEANHGVAVSANRKLQSVGLSTAMKTDIKKFRPAGSKFPTITALGKEWVEHSLSGQLTYTEIVYLFASIFGLDAGQPTDNLDGSFTWLFSPKANQADNFVTFTIEQGGSVRSQRSTYGLVKDLTLNFSRDEATVEGGTLAQALEDNVIMTAAPSAIDLVPVLPTHICIYLSDTFAGLDAADPLQRVLSCSYSMSDRFGAIWPMNRNLNSFGAVVETEPKPQLKLKMEADAEGMALLNTMRGGSTKFLRIEAVGDEIAAGVPYELVIDTAVQVEEPGEFEDADGLYAIEWTFTAIQDSAWNKATQLSVTNSISTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGB6</accession>
    <name>A0A0P6XGB6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Radical SAM core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_18995</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064616.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18995"/>
    <dbReference type="EnsemblBacteria" id="KPL70127">
        <property type="protein sequence ID" value="KPL70127"/>
        <property type="gene ID" value="ADN00_18995"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023885">
        <property type="entry name" value="4Fe4S-binding_SPASM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13186">
        <property type="entry name" value="SPASM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04085">
        <property type="entry name" value="rSAM_more_4Fe4S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="5">
        <location>
            <begin position="134"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL70127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="466" mass="51887" checksum="5196864424AB996D" modified="2016-01-20" version="1">MSSIFTQFSEWLNRGAAPAPPRAGLYHFLIQDEGEKTRVHLRVEADGHALLLINASRVLHLNPTAAYLAFLYLHHTPATKAASALSRYYDVPSYQAIADFKAISDQLRDLIDPMGPCPVCEMELETNVPFSSQPSAPYRMDLAVTYRCNNDCAHCYNARSRNFPELGTEQWYAILDRLWQLSIPHIVFTGGEPTLREDLPQLIAHAESNGQITGINTNGRRLAREGYVDQLRDAGLDHIQITFESHVPEIHDRMVNHPGAWKETLAGLEKALQSGLFVMTNTTMLTDNVEHLEGTLQFLARLGVPTVGLNALIYSGRGSKVGTGLPESRLPALLTVARQMTDANHQRLIWYTPTQYCNFDPEQMELGIKGCTAALYNMCIEPDGSVLPCQSYYQSLGNIQSDEWDAIWNHPLALSLRERRNLPAACKACLFEHECGGGCPLARSAGETKPPVAINPLLHEETEIRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGC0</accession>
    <name>A0A0P6XGC0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PfkB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05710"/>
    <dbReference type="EnsemblBacteria" id="KPL78736">
        <property type="protein sequence ID" value="KPL78736"/>
        <property type="gene ID" value="ADN00_05710"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PfkB" evidence="1">
        <location>
            <begin position="45"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="346" mass="38380" checksum="EF1743B223CDCB09" modified="2016-01-20" version="1">MDEARLTQILDRFTSVNLLVLGDYFLDCYLTMDRNLSEISLETNLEAYQVIEMRKYPGAAGTVAGNLRSLEVNVTALGICGDDGNGYDLRKKLAAIQINPETLLHCPNRFTPTYNKPMMREPDGHEHELNRMDVKNRLPLPEEVEQQIITKLRELLPQVDGVLVVDQVKERNCGVITDRVREEIQSLARSHPQKLFMVDSRDFAGLYTDVIIKTNLSEAVKAANYPADMPLTSEQIKACCRIIYSRTHRPIVITRGERGAIIYQGDPESLSEIPTYQVSGPIDIVGAGDSVSASTGAALCAGASLEEAVFIGNLTASLIIQQIGVTGTTTRARILERYHEFIGQKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGI6</accession>
    <name>A0A0P6XGI6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidase M24</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_06365</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78837.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062124.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78837">
        <property type="protein sequence ID" value="KPL78837"/>
        <property type="gene ID" value="ADN00_06365"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001714">
        <property type="entry name" value="Pept_M24_MAP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00599">
        <property type="entry name" value="MAPEPTIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M24" evidence="1">
        <location>
            <begin position="162"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78837.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="403" mass="44919" checksum="F1DB262B9330B23B" modified="2016-01-20" version="1">MSNSEYQVAREKIETATNYLQQNHVDAWLILTREGSDPAMPLMVGVRSVHEAAIFLRKDGDHTVLCSQSDRGNYQSTGLFQNVQVYEKDFEANLSDVLAQMNPSRLMLNFSQTDHLSDGLSLGQYMMLQKIVGPEKLASIEISSENLQKQLRGIKSPTEVERLQKAIDITIEIYDEVFSKLKCGLSEKEISNFFIQGMKNRGVTNGIGSAYDPPIVCLVRAGLAHRQPGDARVIPGDILIMDFSVKYRDYVSDIARTVYFLKEGETQAPADIQHAFETAHRAITTVIDYIGPGKKGWQVDQVGRQVIENGGFPTVRHSVGHQIGRNCHDGGVTLGPRRAYPRPEVEGEVQVGELYAIEPTVIQDNGLPCMLVEENILITESGARILSRRQNELVLIPFNSEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGU1</accession>
    <name>A0A0P6XGU1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_03465</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the autoinducer-2 exporter (AI-2E) (TC 2.A.86) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03465"/>
    <dbReference type="EnsemblBacteria" id="KPL78965">
        <property type="protein sequence ID" value="KPL78965"/>
        <property type="gene ID" value="ADN00_03465"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002549">
        <property type="entry name" value="AI-2E-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21716">
        <property type="entry name" value="PTHR21716"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01594">
        <property type="entry name" value="AI-2E_transport"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="26"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="119"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="176"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="203"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="239"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="279"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL78965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="376" mass="41074" checksum="EFB6D2ECD1AF3DCE" modified="2016-01-20" version="1">MAFVLSYLLYPIVSVIRQRTKMNWRLTTTLIFVLIVIALLGLLTWGGFTVVDQINSLIRFLQKAIANLPAYLEQLSATKISIGPFEYSLQAFDLEALGSQLLGMIQPILSQVGSLVTGLATGAASTLGWGAFTLLISYFIVSETGGSSSRLLSLDIPGYEYDVERIGKELGRIWNAFLRGQIILIALTIVVYTIALGSLQVRFFFGLAVLAGLARFVPYVGPAIAWVVYFLVSIFQGHTVFGLSPFWYAALVVGIGLLLDNSIDSLITPRLMGNALQVHPAAVMVAALTAATLLGIIGVLLAAPVLASIKLVVAYAMRKMFDLDPWEHLDKELTESGGKLSLAYMDFGDMAKSLWNWLNQSVLMRISNLFKKGKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XHS8</accession>
    <name>A0A0P6XHS8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_02335</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000010">
        <property type="protein sequence ID" value="KPL79656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061350.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000010.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79656">
        <property type="protein sequence ID" value="KPL79656"/>
        <property type="gene ID" value="ADN00_02335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="234" mass="25425" checksum="A5361A73B1C58086" modified="2016-01-20" version="1">MKIAIGGVVVLALVGGYYWLRASRTSSRSLQVIQWIRDPASHPEWAVQARQRCAGAPFLLPTSGLIGFLWDDSFRPGHRHAGIDIFGGSEPGVTPVYSAYDGYLTRMEDWKSSIIIRIPSDPLNPGQQIWTYYTHLADPDGSSFIVADFPPGTHEVFIPAGTLLGYQGNYSGTPGSPTGIHLHFSVVKDDGSGHFLNELEIVNTLDPSPYLGLPLNAHTNPNQIPICAPSETEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XIF8</accession>
    <name>A0A0P6XIF8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_17830</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000043">
        <property type="protein sequence ID" value="KPL70895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064396.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000043.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17830"/>
    <dbReference type="EnsemblBacteria" id="KPL70895">
        <property type="protein sequence ID" value="KPL70895"/>
        <property type="gene ID" value="ADN00_17830"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="73" mass="8368" checksum="6DE4B72383F62D1C" modified="2016-01-20" version="1">MVSKLLLEMLRCPVCVREEKGLLDFYKESWLVCQDCGRKYPVVEDIPVMLIEEGDKWVSTPVESLPVPPPSMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XJ46</accession>
    <name>A0A0P6XJ46_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ribonuclease J</fullName>
            <shortName evidence="9">RNase J</shortName>
            <ecNumber evidence="9">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">rnj</name>
        <name evidence="12" type="ORF">ADN00_17650</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">An RNase that has 5'-3' exonuclease and possibly endonuclease activity. Involved in maturation of rRNA and in some organisms also mRNA maturation and/or decay.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer, may be a subunit of the RNA degradosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the metallo-beta-lactamase superfamily. RNA-metabolizing metallo-beta-lactamase-like family. Bacterial RNase J subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="9"/>
    <dbReference type="EMBL" id="LGCL01000042">
        <property type="protein sequence ID" value="KPL71224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064373.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000042.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17650"/>
    <dbReference type="EnsemblBacteria" id="KPL71224">
        <property type="protein sequence ID" value="KPL71224"/>
        <property type="gene ID" value="ADN00_17650"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2796"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004534">
        <property type="term" value="F:5'-3' exoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01491">
        <property type="entry name" value="RNase_J_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011108">
        <property type="entry name" value="RMMBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004613">
        <property type="entry name" value="RNase_J"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042173">
        <property type="entry name" value="RNase_J_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030854">
        <property type="entry name" value="RNase_J_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041636">
        <property type="entry name" value="RNase_J_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001587">
        <property type="entry name" value="RNase_J_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07521">
        <property type="entry name" value="RMMBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17770">
        <property type="entry name" value="RNase_J_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004803">
        <property type="entry name" value="RnjA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00649">
        <property type="entry name" value="MG423"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01292">
        <property type="entry name" value="UPF0036"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7 9" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 9" id="KW-0540">Nuclease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="9" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Lactamase_B" evidence="11">
        <location>
            <begin position="18"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9 10">
        <location>
            <begin position="362"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR004803-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KPL71224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="544" mass="59892" checksum="98E1D45346D316CE" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XJB1</accession>
    <name>A0A0P6XJB1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">M20_dimer domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_01970</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000007">
        <property type="protein sequence ID" value="KPL80062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061285.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000007.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01970"/>
    <dbReference type="EnsemblBacteria" id="KPL80062">
        <property type="protein sequence ID" value="KPL80062"/>
        <property type="gene ID" value="ADN00_01970"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2320"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00758">
        <property type="entry name" value="ARGE_DAPE_CPG2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="2">
        <location>
            <begin position="238"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL80062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="486" mass="53058" checksum="3431F3B4E7D78372" modified="2016-01-20" version="1">MQPLIFFLIALPVALVLVVLIRALTFSRPAPALPADEPLKIDSLAAAQHLSHAVQCQTISWSESQPASAESLLQLHQTLRQDFPLVHQQLTLHTINQFSLVYEWPGSDPALKPVLFMAHQDVVPVDEATLDRWEQPPFSGRIADGFVWGRGTLDVKNQVTALLDAAEHLLARGYCPARGIFLAFGHDEEISGRQGAQQVSAWFAARGTTFEAVLDEGLAVVENALPGVKGPIALIGAAEKGYLSLKLDVTTDAGHSSTPPAETSISILAHALARLQRHPQPAHVEMMKPLFQALGPAAPFTLRLVFANLWLFGGLARKQLDASPQSSAAIRTTTAPTILTAGMKDNVLPRSASAVVNFRLLPGDTTQSVIQRVRQTIRDPRVSIETLHESAREASPISPTDSTAYQRLSETIQRTFGPVPVAPFTMLGASDAYHYTPLSANVYRFCPVHLDSKDLSRVHGLNERISLKNLGNMLRFYILLMQSWGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XJL3</accession>
    <name>A0A0P6XJL3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Phosphoribosyl-ATP pyrophosphatase</fullName>
            <shortName evidence="8">PRA-PH</shortName>
            <ecNumber evidence="8">3.6.1.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">hisE</name>
        <name evidence="9" type="ORF">ADN00_17475</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>1-(5-phospho-beta-D-ribosyl)-ATP + H2O = 1-(5-phospho-beta-D-ribosyl)-5'-AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:22828"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:59457"/>
            <dbReference type="ChEBI" id="CHEBI:73183"/>
            <dbReference type="EC" id="3.6.1.31"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the PRA-PH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.31" evidence="8"/>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71471.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064334.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17475"/>
    <dbReference type="EnsemblBacteria" id="KPL71471">
        <property type="protein sequence ID" value="KPL71471"/>
        <property type="gene ID" value="ADN00_17475"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.562"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00007"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004636">
        <property type="term" value="F:phosphoribosyl-ATP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd11534">
        <property type="entry name" value="NTP-PPase_HisIE_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01020">
        <property type="entry name" value="HisE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008179">
        <property type="entry name" value="HisE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021130">
        <property type="entry name" value="PRib-ATP_PPHydrolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01503">
        <property type="entry name" value="PRA-PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03188">
        <property type="entry name" value="histidine_hisI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL71471.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="97" mass="10848" checksum="AFCB6D90A356BDBF" modified="2016-01-20" version="1">MKIDELYQIIADRKAAPQEGSYTNYLFDKGEDKILKKVGEEAMEVLLAAKGEGDQRLIEEVSDLTYHLLVLLASRGITPADIGAELEKRHQPRPPQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XJU2</accession>
    <name>A0A0P6XJU2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HATPase_c domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_12175</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063289.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12175"/>
    <dbReference type="EnsemblBacteria" id="KPL76093">
        <property type="protein sequence ID" value="KPL76093"/>
        <property type="gene ID" value="ADN00_12175"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13581">
        <property type="entry name" value="HATPase_c_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HATPase_c" evidence="1">
        <location>
            <begin position="15"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="143" mass="15894" checksum="90404F331766933E" modified="2016-01-20" version="1">MSEQCFHAAYPGRFSSLRLISSFVREAAQKTGLDDCTIYAVETAVDEACSNIIEHAYGAEDLGEIQCECCVLPDRLIIILKDQGKPFDPSAIAAPNLEVPLDERTDHGLGLYFMRQMMDDVRFDFVEGVGNILTMVKMKEKPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XJV2</accession>
    <name>A0A0P6XJV2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_12280</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76111">
        <property type="protein sequence ID" value="KPL76111"/>
        <property type="gene ID" value="ADN00_12280"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="224" mass="25717" checksum="FFD233AB546393A2" modified="2016-01-20" version="1">MVWQPFIDEQSIFELKLPDIGDAPDQYSIFPQYLPNSKIVIYPCNQCGTNEFQAYDLESNKVKWTLDFGEGRETGLHWSFIPSPDGKKTVFYFGLNKLWIVDTNGESLLKISLPFSESYNWVVRAIRWSPDGKKLAFMRYTPDGSDPILTIISIHEHQQTSYCSNLGVGNIHWSFDGQYIVHSIQEQNDDGEVTSSIFSVVQLETGNTYQKRFPENLSVIGWLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XK22</accession>
    <name>A0A0P6XK22_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_13105</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000029">
        <property type="protein sequence ID" value="KPL75292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063475.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000029.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13105"/>
    <dbReference type="EnsemblBacteria" id="KPL75292">
        <property type="protein sequence ID" value="KPL75292"/>
        <property type="gene ID" value="ADN00_13105"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2899"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="domain" description="AB hydrolase-1" evidence="2">
        <location>
            <begin position="58"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL75292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="313" mass="33030" checksum="2709DE8D6F073210" modified="2016-01-20" version="1">MIGGALSLVVLIVIGLMLVRYQKDMRAYRARLEGLNLETASTACGKIEYARQGSGYPVLVVHGNGGGVDQGLGMASGYIPAGLKVIAPSRFGYLGTPMPANATVEMQADAYACLLDALGIEKAAIFTSSAWVTSVTQFALRHPERVSAIILHSPNSPGEVGLVAPPKPVFSAMLHSDFIYWIMITYFGDGMQSLVGVPKGFALTPELQEVVTHTLGSVMPVSSRADGMVFDTYVSNPAINDCPLEQISTPTLVISAADDPMTLHSSARNLAALIPGAQFKAIADGGHMMLGHAEEVNQAIQVFLSSAVPELAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKF8</accession>
    <name>A0A0P6XKF8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">D-ribose pyranase</fullName>
            <ecNumber evidence="2 5">5.4.99.62</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rbsD</name>
        <name evidence="6" type="ORF">ADN00_15880</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>beta-D-ribopyranose = beta-D-ribofuranose</text>
            <dbReference type="Rhea" id="RHEA:25432"/>
            <dbReference type="ChEBI" id="CHEBI:27476"/>
            <dbReference type="ChEBI" id="CHEBI:47002"/>
            <dbReference type="EC" id="5.4.99.62"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Carbohydrate metabolism; D-ribose degradation; D-ribose 5-phosphate from beta-D-ribopyranose: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodecamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the RbsD / FucU family. RbsD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.62" evidence="2 5"/>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL71983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064023.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15880"/>
    <dbReference type="EnsemblBacteria" id="KPL71983">
        <property type="protein sequence ID" value="KPL71983"/>
        <property type="gene ID" value="ADN00_15880"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3609"/>
    <dbReference type="UniPathway" id="UPA00916">
        <property type="reaction ID" value="UER00888"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062193">
        <property type="term" value="F:D-ribose pyranase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016872">
        <property type="term" value="F:intramolecular lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048029">
        <property type="term" value="F:monosaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019303">
        <property type="term" value="P:D-ribose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1650.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01661">
        <property type="entry name" value="D_rib_pyranase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023064">
        <property type="entry name" value="D-ribose_pyranase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023750">
        <property type="entry name" value="RbsD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007721">
        <property type="entry name" value="RbsD_FucU"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37831">
        <property type="entry name" value="PTHR37831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05025">
        <property type="entry name" value="RbsD_FucU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102546">
        <property type="entry name" value="SSF102546"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="120"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="20"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="28"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL71983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="131" mass="14252" checksum="A9F7FCB8BC80086B" modified="2016-01-20" version="1">MKKTTLLNSDLSYLISTMGHFDTLVIGDAGLPIPASTERIDLALVRGVPGAIETLRAVLSELQVEYVILASETTQNNPQFEQDVRALLPGVKVEYVSHEELKRRSADARAVVRTGECKPYANVILVAGVAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XLN2</accession>
    <name>A0A0P6XLN2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_11975</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063250.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11975"/>
    <dbReference type="EnsemblBacteria" id="KPL76060">
        <property type="protein sequence ID" value="KPL76060"/>
        <property type="gene ID" value="ADN00_11975"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3871"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2-Hacid_dh" evidence="3">
        <location>
            <begin position="31"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="2-Hacid_dh_C" evidence="4">
        <location>
            <begin position="114"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL76060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="324" mass="35830" checksum="83440FD93E072441" modified="2016-01-20" version="1">MKTVLLSAPYMIPYVERFRPVFSHYGLNLIVPEVLERMEEDHLLQHAGQFDGAICGDDRYTAKVMEACQPRLKVISKWGTGIDSLDQKAAARWGIQIRNTPNAFTLPVSDSVLGYMLAFARRQPWMDAEMKAGNWEKLMGRSLSECTLGVIGVGNVGKAVLRRARAFGMRLLGNDIRPIEPDFIVEQGVEMVSLAVLMAQSDFISVNCDLNPTSYHLINDASLANVKRGAVLINTARGPIVEEAALVRALQDGRLGGAGMDVFEVEPLPLDSALRQMSQVMLAPHNSNSSPSAWERVHWNTIRNLLLGLEINCEDLDEVRASLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XNW1</accession>
    <name>A0A0P6XNW1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_10110</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062882.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10110"/>
    <dbReference type="EnsemblBacteria" id="KPL76937">
        <property type="protein sequence ID" value="KPL76937"/>
        <property type="gene ID" value="ADN00_10110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00037">
        <property type="entry name" value="Fer4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12837">
        <property type="entry name" value="Fer4_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="31"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="116"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="129"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL76937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="144" mass="15533" checksum="E6C1A63B6C00CEB5" modified="2016-01-20" version="1">MTVIVNESLCKGCGVCVNACPSGAIHMMDGKALIDPQRCDACEKCIGICPTGALQRVEVIDTTPVKSIVVSPQAAANRGLARRPGWVATALAGFGYYLIPRIVDFFASGLERKSSTPQSRLTASARNDSRRPRRRRQRGGRSGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XNW3</accession>
    <name>A0A0P6XNW3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">UDP-N-acetylmuramoylalanine--D-glutamate ligase</fullName>
            <ecNumber evidence="9">6.3.2.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">D-glutamic acid-adding enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">murD</name>
        <name evidence="12" type="ORF">ADN00_07375</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + D-glutamate + UDP-N-acetyl-alpha-D-muramoyl-L-alanine = ADP + H(+) + phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</text>
            <dbReference type="Rhea" id="RHEA:16429"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29986"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83898"/>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the MurCDEF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.9" evidence="9"/>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062339.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07375"/>
    <dbReference type="EnsemblBacteria" id="KPL78278">
        <property type="protein sequence ID" value="KPL78278"/>
        <property type="gene ID" value="ADN00_07375"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3297"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008764">
        <property type="term" value="F:UDP-N-acetylmuramoylalanine-D-glutamate ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00639">
        <property type="entry name" value="MurD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005762">
        <property type="entry name" value="MurD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01087">
        <property type="entry name" value="murD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4 9" id="KW-0132">Cell division</keyword>
    <keyword evidence="5 9" id="KW-0133">Cell shape</keyword>
    <keyword evidence="8 9" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0436">Ligase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 9" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="289"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_M" evidence="11">
        <location>
            <begin position="114"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="116"/>
            <end position="122"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KPL78278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="460" mass="50626" checksum="3A00CA56A9A71AF7" modified="2016-01-20" version="1">MQNWQNRNVIILGAARQGLALARYLTAQGALVTISDQRSPAQLEQARQSLQGKNIRWVLGEHPFSLLEDADLLCLSGGIPFTLPIVIEAQRRGIPLSNDSQIFMQAAPCPVIGITGSAGKTTTTTLVGRILQAAFMPEHTVWVGGNIGLPLIDLVGDIQPADRVVLELSSFQLEQMTLSPQIAAVLNITPNHLDRHGTLEAYTAAKARILDFQTPDSTAVLNREDPGSWNLHSRVRGRLVSFGLQRPQEAFQGAYVENGWCCLFDGQKTLRVVPLKDIQLRGEHNRLNILAAFAIAFAAGCPVQAMIAGLQDFKGVKHRLEFVREYRGAYWYNDSIATAPERTMAAVRSFDEPLLLLLGGRDKNLPWQDLAQMAVRRVDQVVIFGEAAPLIEKALRDAQNGGKSPHIQVVSHLHEAVQAAAKVVTPGMVVLFSPGGTSFDEFKDFEERGERYCEWVNQLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XP80</accession>
    <name>A0A0P6XP80_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_10900</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063027.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77056">
        <property type="protein sequence ID" value="KPL77056"/>
        <property type="gene ID" value="ADN00_10900"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="2">
        <location>
            <begin position="26"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="3">
        <location>
            <begin position="125"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL77056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="183" mass="21362" checksum="9852C39429EFFF16" modified="2016-01-20" version="1">MSLQVEQEAGLITQAESGSKPAFAALYELYLAEIYRYVYYRVMDHMEAEDLIEKVFIKAWESLTRPRPNRQPLQNFRAWLYRIARNTVIDHQRMARHAVSIEDIDRLQVNHPGLQEQVEQDERAQQLAQALSQLDEISREVLLLRFVNQLSHADAATVMGISENHMRVLQYRALKKMKVLLNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQ09</accession>
    <name>A0A0P6XQ09_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Flagellin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_17020</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Bacterial flagellum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the bacterial flagellin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064250.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17020"/>
    <dbReference type="EnsemblBacteria" id="KPL71399">
        <property type="protein sequence ID" value="KPL71399"/>
        <property type="gene ID" value="ADN00_17020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009288">
        <property type="term" value="C:bacterial-type flagellum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="6.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001492">
        <property type="entry name" value="Flagellin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046358">
        <property type="entry name" value="Flagellin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042187">
        <property type="entry name" value="Flagellin_C_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001029">
        <property type="entry name" value="Flagellin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42792">
        <property type="entry name" value="PTHR42792"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00700">
        <property type="entry name" value="Flagellin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00669">
        <property type="entry name" value="Flagellin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00207">
        <property type="entry name" value="FLAGELLIN"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Flagellin_N" evidence="5">
        <location>
            <begin position="11"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="Flagellin_C" evidence="6">
        <location>
            <begin position="349"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="316"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="321"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL71399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="435" mass="45091" checksum="EC07E3CA2BE52AEE" modified="2016-01-20" version="1">MASDLTRIAGNIGAMNSLWSLSNINKQLSVHQSRLASGKRINTAADDPAGLTIATKMRAQSEGLGVALGNISDAKNLLAVAESGIGRINDILIEMRNKAQAGASDTMGSAERAALVQQMSAYAAQVDDIVTQTKWNGEKLIDGTYDTAKSLTFQTGADQGDTTSLSGLKKLSATAADGLALAKVSGAASVTEGQDIAGLISSPVVGAGDNANIENLSTGTYTVRVSGATAGSAKIELLDSNGNAMLISNTPATGLGDATKALTAQDLDGATTDVDFGNGLKVTIANLNGQTNFDLSATVNYTAGNQTVLQFNHDGADRRLNSDGTTSTSSDGGTTWVAGTASEDFSAYMDYINTKLTTVTEQLSKVGSLTGRLTFKEDQVSAAKINVEGAYNRIMNADMAEEQVNASKYQILQQTATAMLAQANSAPQFILSLFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQ12</accession>
    <name>A0A0P6XQ12_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nitric oxide synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_06245</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062103.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06245"/>
    <dbReference type="EnsemblBacteria" id="KPL78817">
        <property type="protein sequence ID" value="KPL78817"/>
        <property type="gene ID" value="ADN00_06245"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026816">
        <property type="entry name" value="Flavodoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12724">
        <property type="entry name" value="Flavodoxin_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="1">
        <location>
            <begin position="3"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="158" mass="17103" checksum="7B96E0ED4EFF8D97" modified="2016-01-20" version="1">MKVLVIYDSVFGNTEKIARAIGEALSPLGDVRVIKVADAAAQEMQGLDYLFVGSPTRAFSPTPAAKQFLKTIPRHALDGVKVAAFDTRADLQEVNSRFLNIMVKFFGYAADPISKRLAQKGGRVIHPPEGFFVKGTEGPLADGELERAAAWAQQVVQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQ14</accession>
    <name>A0A0P6XQ14_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_13595</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063570.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000032.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74333">
        <property type="protein sequence ID" value="KPL74333"/>
        <property type="gene ID" value="ADN00_13595"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL74333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="189" mass="19678" checksum="79EDA621A6061FD8" modified="2016-01-20" version="1">MKSIYGKLIPFLLIVTFVSIACNLPVSVASDPHSPVEVSAQDAQSAVNTLEEAADQLGQSGATTIQLTESQLSALLANQLAGAESGGFSNPQVQIEGEQIWVVGNIQQGPISVGVQLTLAAVKDAAGKPSIQLQSVDFGQFPAPQSMVDNLSSFVNTSINQAMSETAGELEIVDLVVGNDAITITVRKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQD7</accession>
    <name>A0A0P6XQD7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SLT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_03510</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061581.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03510"/>
    <dbReference type="EnsemblBacteria" id="KPL78973">
        <property type="protein sequence ID" value="KPL78973"/>
        <property type="gene ID" value="ADN00_03510"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008258">
        <property type="entry name" value="Transglycosylase_SLT_dom_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01464">
        <property type="entry name" value="SLT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133175" description="SLT domain-containing protein" evidence="3">
        <location>
            <begin position="23"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="130"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="472"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="domain" description="SLT" evidence="4">
        <location>
            <begin position="654"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="25"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="25"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL78973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="804" mass="90262" checksum="BA110D2C4038D2C7" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQR7</accession>
    <name>A0A0P6XQR7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_04635</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061788.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04635"/>
    <dbReference type="EnsemblBacteria" id="KPL79147">
        <property type="protein sequence ID" value="KPL79147"/>
        <property type="gene ID" value="ADN00_04635"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="7"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="122"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="122"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL79147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="227" mass="25966" checksum="2E2FC748E239290D" modified="2016-01-20" version="1">MARPRGKILLIEGKRSDHPSFFSGLTRKGFDVESVGTGKLASERLQTSLPDVVLVDAASMRTSGKRICQSIRADAPGVPILLVVDADYDHMERLDADVVLAQPFTLQKLLNRMRPLLPTDDQNLLKVGPIHLDVEHRWARCQERQAQLTPRLVMLLRALMERPGEVIERTDLFRVVWETEYTGDTRTLDVHVSWLRQALEEDARHPRYLKTVRGVGYRLDVEPKKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQX4</accession>
    <name>A0A0P6XQX4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_05045</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061863.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05045"/>
    <dbReference type="EnsemblBacteria" id="KPL79211">
        <property type="protein sequence ID" value="KPL79211"/>
        <property type="gene ID" value="ADN00_05045"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011066">
        <property type="entry name" value="MscS_channel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011014">
        <property type="entry name" value="MscS_channel_TM-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="SSF50182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82689">
        <property type="entry name" value="SSF82689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82861">
        <property type="entry name" value="SSF82861"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="16"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="92"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="134"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="164"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL79211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="351" mass="39431" checksum="AE036238ECB02F65" modified="2016-01-20" version="1">MSFWTSVFWGNPTRQWVAGLIAAAVSFGVLMLVKRLVIKHIKRAAEKSQSDVADFLVRLFEQTKDLFFLALSLYIGMQYLILVDNISRTARVIILLILILQAGFWASSLVSFWVNREVKKSLDNGRRDSNTLSVLGLVMKGVIWAVVIVLVLDNIPGVKVDTLIASLGITGIAVGLAVQNILGDLFASLSIALDKPFVIGDSIVVDDLTGTIEKIGLKSTRVRSLSGEQIIFSNSDLLKSRIRNYQRMQRRRVAFMLNVDYNTPPDQLDRIPDMIRECVDGVEDVTFARSHLAALGEFAIQFETVYWVESDDYVLFMDVKQRILRGVLARFQTEGIRLSFPTQTLHTHLHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XRC8</accession>
    <name>A0A0P6XRC8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PHB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_03265</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the band 7/mec-2 family. HflC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000014">
        <property type="protein sequence ID" value="KPL79357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061526.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000014.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79357">
        <property type="protein sequence ID" value="KPL79357"/>
        <property type="gene ID" value="ADN00_03265"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052547">
        <property type="term" value="P:regulation of peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03401">
        <property type="entry name" value="SPFH_prohibitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010200">
        <property type="entry name" value="HflC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000163">
        <property type="entry name" value="Prohibitin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42911">
        <property type="entry name" value="PTHR42911"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00679">
        <property type="entry name" value="PROHIBITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="domain" description="PHB" evidence="3">
        <location>
            <begin position="57"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL79357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="350" mass="38034" checksum="0D789C85EFC3DEF1" modified="2016-01-20" version="1">MNVASLFQGVSLLAWLAFFLSVIFVVVQASRGKAVKNGRTILIVVAVAAIVLTTLSSGIVFVNPQERGVVISAVAPKGYREQALTPGLRWIIPFAESVVKYPISRQTYTMSIAPSEGQIFGDDSIEARTADGQKVLVDASVIYQINPEKVIEVHINWQDRYSTDLVRAVSRGVIRDAVSQFGVEDVYSRQRAALTQMISDEMAKSLDDNGLTLVDFVLRNISFSDEYAASVEQKQIAEQQAQQAKFVVEQRKQEAEQARQVAQGKADASVIAAQGDAEARIIQAKAEAEALELIAAALADNPDLLTYQYINQITPNVEVMLLPSNSPFVFPLPTMGPQEPAASPTPAPAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XSD2</accession>
    <name>A0A0P6XSD2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3 4">Single-stranded DNA-binding protein</fullName>
            <shortName evidence="2">SSB</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_12930</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063436.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000027.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12930"/>
    <dbReference type="EnsemblBacteria" id="KPL75540">
        <property type="protein sequence ID" value="KPL75540"/>
        <property type="gene ID" value="ADN00_12930"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1281"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04496">
        <property type="entry name" value="SSB_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00984">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000424">
        <property type="entry name" value="Primosome_PriB/ssb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011344">
        <property type="entry name" value="ssDNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10302">
        <property type="entry name" value="PTHR10302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00436">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002070">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00621">
        <property type="entry name" value="ssb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50935">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR002070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL75540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="132" mass="14567" checksum="1A8BFF29EF81A793" modified="2016-01-20" version="1">MYQTLILVGNLGKEPEMRYTPTEQPVTTLSVAANRRHTSNGGQPVKETTWFRVTVWGKQAETCNQFLHKGSKVLIEGRLTPDPDTGGPRVWESNGKHGASYEVAASIVRFLSGREDGEEGETVGNFDNDIAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUH9</accession>
    <name>A0A0P6XUH9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF5667 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_10905</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063028.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77057">
        <property type="protein sequence ID" value="KPL77057"/>
        <property type="gene ID" value="ADN00_10905"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2661"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043725">
        <property type="entry name" value="DUF5667"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18915">
        <property type="entry name" value="DUF5667"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="107"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5667" evidence="3">
        <location>
            <begin position="134"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="252"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="325"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF18915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL77057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="344" mass="37901" checksum="C0DE08AAB3F81E8F" modified="2016-01-20" version="1">MPDLKNTLPGNTQPAQRLADLLDNRGEQGDVPLPLLEHEEQELQELLAVADWITQAPKAEPSAQFRQQSRQRILKQIDQPKPVTFWQGLRLIFTEGLSSFKIKRRTALVLMSIVLLVAMLSVGGTNIVLASSDALPGDSLYNIKILIEQAQLVVASPEQRVEQINGNLETRVEEIEALVEAGRFEDLQVALATFDSEVSDLANAMASLPPQSPERSEAHQLLLETAHNNRIQVLTSLLDKVPESARPAIEKAIQSTSDLEPQETKGKPEKTVTPQPTKEKPAGKPEDINTPEKGKPTTLSTPEKRSIPTATPKPTQTPKPTKVPPGQVDKDKPDKPEKPEKKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XVR5</accession>
    <name>A0A0P6XVR5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Aldehyde:ferredoxin oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_02820</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AOR/FOR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000013">
        <property type="protein sequence ID" value="KPL79406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02820"/>
    <dbReference type="EnsemblBacteria" id="KPL79406">
        <property type="protein sequence ID" value="KPL79406"/>
        <property type="gene ID" value="ADN00_02820"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2197"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016625">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.569.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.599.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.9.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013984">
        <property type="entry name" value="Ald_Fedxn_OxRdtase_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013985">
        <property type="entry name" value="Ald_Fedxn_OxRdtase_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013983">
        <property type="entry name" value="Ald_Fedxn_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036503">
        <property type="entry name" value="Ald_Fedxn_OxRdtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001203">
        <property type="entry name" value="OxRdtase_Ald_Fedxn_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036021">
        <property type="entry name" value="Tungsten_al_ferr_oxy-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01314">
        <property type="entry name" value="AFOR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02730">
        <property type="entry name" value="AFOR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00790">
        <property type="entry name" value="AFOR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48310">
        <property type="entry name" value="SSF48310"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56228">
        <property type="entry name" value="SSF56228"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AFOR_N" evidence="8">
        <location>
            <begin position="1"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL79406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="578" mass="61316" checksum="8A2F735C23CED501" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XW65</accession>
    <name>A0A0P6XW65_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">30S ribosomal protein S1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_14590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000035">
        <property type="protein sequence ID" value="KPL73566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063766.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000035.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14590"/>
    <dbReference type="EnsemblBacteria" id="KPL73566">
        <property type="protein sequence ID" value="KPL73566"/>
        <property type="gene ID" value="ADN00_14590"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2084"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035104">
        <property type="entry name" value="Ribosomal_protein_S1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10724:SF7">
        <property type="entry name" value="PTHR10724:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00681">
        <property type="entry name" value="RIBOSOMALS1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="S1 motif" evidence="1">
        <location>
            <begin position="34"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="1">
        <location>
            <begin position="120"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="1">
        <location>
            <begin position="216"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="1">
        <location>
            <begin position="301"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL73566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="407" mass="45051" checksum="22D56E723689844F" modified="2016-01-20" version="1">MEQNGAQGAMPENENNMADLLEQEGLDIDFPKAGDIRDGVIASISQGQILVSVGTKSEGVISGREFDQIPEEDLKEMKVGQEIKVYVITPEDSQGTLVLSFNRAQEAVSWDKAEALMESKASFSSKIIGYNKGGLIVPMGGLRGFVPASQVSLSRRAEVSGDTPEDRFGAMVGSKIDVCVIEVDRERRRLILSERAASTETRESLKERVIDELQEGEIRVGRVTSLADFGAFVNISGADGLVHLSEISWDRINHPSEVLEVGQEVKVKVISIDRDKKRIGLSIRQLQDDPWAAKANEFQVGQLVEGTITRLTKFGAFARLQDDVEGLIHISEISEKRIEHPKEVLKEGDVVTLRIIRLDPENHRIGLSLRRVDSMAFAEMDWQTLLDEELMNAPEAEEPEEGEASEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XWK5</accession>
    <name>A0A0P6XWK5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PGA_cap domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_08090</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CapA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08090"/>
    <dbReference type="EnsemblBacteria" id="KPL77835">
        <property type="protein sequence ID" value="KPL77835"/>
        <property type="gene ID" value="ADN00_08090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019079">
        <property type="entry name" value="Capsule_synth_CapA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09587">
        <property type="entry name" value="PGA_cap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00854">
        <property type="entry name" value="PGA_cap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGA_cap" evidence="2">
        <location>
            <begin position="239"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="542" mass="59467" checksum="CDBA717763055A99" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XXF6</accession>
    <name>A0A0P6XXF6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_01715</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061232.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80585">
        <property type="protein sequence ID" value="KPL80585"/>
        <property type="gene ID" value="ADN00_01715"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="6"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL80585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="313" mass="34538" checksum="24FF9936F155659E" modified="2016-01-20" version="1">MIEPVIEVTQLTHQYNGHAALDQLSFSAQKGTVVGLLGPNGAGKTTTVRLLNGLFPPTSGQMRVLGFDPARQGGELRRRTGVLTETPALYERLTARQNLAFFGTLCGLSAAEVSARAQELLDFFELRERANDRVQTYSKGMKQRLAIARALLNRPQILFLDEPTSGLDPEASQQVHELIANIRDQDGQTVILCTHNLFEAERLCDKMGILNRGRLLDFGSLTELRQRHAPGLWLQVRFYQSAPAAIPSISGLMEAVMENELTWRLKVSEEAVVPALVSQMAASGAQILSLQPQSLSLEDVYFKLQNAQKEGVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XY41</accession>
    <name>A0A0P6XY41_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNase_H_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_00305</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060959.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00305"/>
    <dbReference type="EnsemblBacteria" id="KPL81024">
        <property type="protein sequence ID" value="KPL81024"/>
        <property type="gene ID" value="ADN00_00305"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038720">
        <property type="entry name" value="YprB_RNase_H-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13482">
        <property type="entry name" value="RNase_H_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase_H_2" evidence="1">
        <location>
            <begin position="96"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL81024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="416" mass="47499" checksum="710F2F11E284FE59" modified="2016-01-20" version="1">MESISDRLKSLGVQKGFAKKSESRDSRAQQGQRTLQSLLNGEVQTNFYGESLSIREVYPPEYRHGVTNLSHPIDTDVICKVSRLASDINLQLDEILFLDTETSGLGGGTGTFAFLIGLGFYTGQGFQVQQLFMRDPSEEPSMLAELIKITTRFKAVLTYNGKSFDIPLLNNRYILNGLTSPFIQYPHIDLLQITRKIWSNRFDNRSLGHLENQLLGFFRSGEEVPGWMIPQIYFDFLADHNPIPLSGVFYHNKIDILSLAGLTLLAGETLSYPNSTDIHQLDQLSVAKVYQTLGRTEEALSIYDQCIQKDLTPPQQLQAIMNSAEMCKRDRKWDLALPLWKEASRLGSIEACIEIAKYLEHTTKEYDDALAWTEKARMLILNQTSYYYQQMKLAEVEKRSRRIQQKTQREKSTNND</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XZR1</accession>
    <name>A0A0P6XZR1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_06595</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000017">
        <property type="protein sequence ID" value="KPL78584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062186.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000017.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78584">
        <property type="protein sequence ID" value="KPL78584"/>
        <property type="gene ID" value="ADN00_06595"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="219"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="292"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="315" mass="35328" checksum="8D39D90E1523C9FE" modified="2016-01-20" version="1">MKSPTGTFNLQVLKARLQRLNYPLSRRARLIILAEVIFGLAAWLLLRWMILSPAVSAEWKLVLISLAALAFLIVGFSSLRMALEPQESRLKARSATMLVVLACAYLVPAFVFVLPDWLQALRAPVPGRINSAGQPWFFIWQALVLAGYAFLRRWSIPLPPQPARLEQPTQPSRPVAWPWVLSASLLAGLAVWLAGVYLIDLLSNTFVMDFPPLNPLFEGFVLLIALTAAPWAEEYFFRIELRSLLRPLGGDLYPALASAALFSALQARPVLFLPAFCLSLAAHRLTQWTGRLYPAVIAHALFNLLIFWQAWYLIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y030</accession>
    <name>A0A0P6Y030_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Cobalt transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_05390</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061950.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05390"/>
    <dbReference type="EnsemblBacteria" id="KPL78685">
        <property type="protein sequence ID" value="KPL78685"/>
        <property type="gene ID" value="ADN00_05390"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1551"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1510.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002524">
        <property type="entry name" value="Cation_efflux"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036837">
        <property type="entry name" value="Cation_efflux_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027469">
        <property type="entry name" value="Cation_efflux_TMD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01545">
        <property type="entry name" value="Cation_efflux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160240">
        <property type="entry name" value="SSF160240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161111">
        <property type="entry name" value="SSF161111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01297">
        <property type="entry name" value="CDF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="133"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="163"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="192"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL78685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="312" mass="35286" checksum="688AE605DA155A23" modified="2016-01-20" version="1">MHTHETEQEQGHNYHHDHFGHHHHTDDSLNNIRVAFFLNLGFTILEIVGGLWTNSLAILSDALHDLGDSFSLGMSWYLHRLSTRSRDNHYSYGYRRFSLLGALLNTLVLMGGSVVIIGQAIPRVLHPEESNAPGMVLFAVIGILVNGAAVLKLRGGQSLNERAVALHLLEDVLGWVAVLAVSVILLFTDWHFLDPLLSLMITLYVLINIFKNLRKTLTLFLQGVPEDVDLQQLDTEILKLTNVISTHHTHVWSLDGERHVLTTHVVIPHTVSREEVLKLKEDIRGITERMNFAHTTVEVEFSDEECRIKEDC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y046</accession>
    <name>A0A0P6Y046_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13395</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063527.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000031.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74828">
        <property type="protein sequence ID" value="KPL74828"/>
        <property type="gene ID" value="ADN00_13395"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133291" evidence="1">
        <location>
            <begin position="28"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="119" mass="12094" checksum="AF48220CE808190D" modified="2016-01-20" version="1">MLSKRVFKTLLIVLVALALSGFTYAFAAANTVPGTRAGDGTGVISGYTVSNIVYNLNAANPGIIDSVSFSLNEAATTVKASVNGTTFADCTLSASTWTCTLPAATTVEAAVSLRVIAAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y0D6</accession>
    <name>A0A0P6Y0D6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Autoinducer 2 aldolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_06020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062065.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06020"/>
    <dbReference type="EnsemblBacteria" id="KPL78785">
        <property type="protein sequence ID" value="KPL78785"/>
        <property type="gene ID" value="ADN00_06020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1684"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004332">
        <property type="term" value="F:fructose-bisphosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00958">
        <property type="entry name" value="DhnA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002915">
        <property type="entry name" value="DeoC/FbaB/LacD_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041720">
        <property type="entry name" value="FbaB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01791">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038992">
        <property type="entry name" value="Aldolase_Ia"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01133">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="292" mass="32092" checksum="194170CC5FCB1132" modified="2016-01-20" version="1">MPEADHEGKNYYEDIPQQGKLFFLKGSSELDWGMKNRLARIFNPNDGRTVMLAIDHGYFQGPTSGLERVDVNILPLMPEADVLMCTRGILRTVVPPSFTIPVVIRASGGPSILKELSDEQIAMDMEDCIRLGVCATAIQVFIGGEFESRSVVNMTRLVDAGLRYGIPTLAVTAVGKDLERNAKYFRLATRICAELGAQYVKTYYVEEDFETVTASCPVPIVIAGGKKRPELDALKMAYNAISQGAAGVDMGRNIFQSDSPIGMMKAVKAIVHGNETPEKAYDLYQTIKNDGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y2U3</accession>
    <name>A0A0P6Y2U3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Metal-dependent carboxypeptidase</fullName>
            <ecNumber evidence="1">3.4.17.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_04040</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Broad specificity carboxypetidase that releases amino acids sequentially from the C-terminus, including neutral, aromatic, polar and basic residues.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Release of a C-terminal amino acid with broad specificity, except for -Pro.</text>
            <dbReference type="EC" id="3.4.17.19"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="2">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.17.19" evidence="1"/>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061886.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79233">
        <property type="protein sequence ID" value="KPL79233"/>
        <property type="gene ID" value="ADN00_04040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.163"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001333">
        <property type="entry name" value="Peptidase_M32_Taq"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34217">
        <property type="entry name" value="PTHR34217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02074">
        <property type="entry name" value="Peptidase_M32"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006615">
        <property type="entry name" value="Zn_crbxpep_Taq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00998">
        <property type="entry name" value="CRBOXYPTASET"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="261"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="260"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="290"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR006615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR006615-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR006615-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL79233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="496" mass="56971" checksum="69511F22321189E9" modified="2016-01-20" version="1">MEQLKALLGEINDLVGAEAVLGWDQQTYMPKAGAEDRGSQLATLAKIRHEKSTCDELGQLLDDLKSYETHLDPDSDEACLIKLARRNYEKQTKVSAEWVGEFAKITTIGQSEWEKARAENNFEAFRPVLEQIFELRRAYADFFKPYDHIYDPMLDDFEPGLKTAEVKEIFSKLRPQQVELIRQIAEKPEIDDSFVYLDYSEQGQWDFGVRVLNDFGFDWNRSRQDKSAHPFTTSFGIDDVRITTRFVPNLGTSSLFSTMHEGGHALYELGFDHALARTPLAAGASMAVHESQSRMWENMVGRSKAFWKHYYPLYQETFRSILGNVSMEDYYRGINKVKPSLIRVEADEATYNLHIMLRLELEIAVMEGQLAVRDLPAAWNARMEEYLGIVPPNDAKGVLQDVHWSGGMMGYFPTYALGNLVSAQLWECIQRDLPNLEEQIEAGKFDELLGWLREKIHRHGAKFEPQDLVKRVTGSKINPDAYMRYLSEKFSAIYDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y395</accession>
    <name>A0A0P6Y395_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Probable membrane transporter protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_02790</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000013">
        <property type="protein sequence ID" value="KPL79380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061438.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000013.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02790"/>
    <dbReference type="EnsemblBacteria" id="KPL79380">
        <property type="protein sequence ID" value="KPL79380"/>
        <property type="gene ID" value="ADN00_02790"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2191"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002781">
        <property type="entry name" value="TM_pro_TauE-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01925">
        <property type="entry name" value="TauE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="35"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="148"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="195"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="237"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL79380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="256" mass="26867" checksum="4544268244C15E07" modified="2016-01-20" version="1">MEFTWLQYLLVGLAALAAGAVNALAGGGTLITFPILTAVGIPAVAANVTNTVALCPGYFGATWAQWKEIKEQRGRAALLLPVSALGGIIGGLLLLNTGERAFRDLVPYLILLASLLLAVGEPLKAWLARRASQRPSSPRSHHFWSAGLVLLAAIYGGYFGAGLSVIVLAVLGLALTDSLTRLNALKQAIAFSVNIAAAIYFLFSGSVVWQVVLLMWVCSLIGGALGGKLAGRIPAPTLRWTVVCIGVAVSVIYFLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y399</accession>
    <name>A0A0P6Y399_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_12215</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063296.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12215"/>
    <dbReference type="EnsemblBacteria" id="KPL76099">
        <property type="protein sequence ID" value="KPL76099"/>
        <property type="gene ID" value="ADN00_12215"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004107">
        <property type="entry name" value="Integrase_SAM-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02899">
        <property type="entry name" value="Phage_int_SAM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="5">
        <location>
            <begin position="16"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="4">
        <location>
            <begin position="123"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL76099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="307" mass="34894" checksum="9AD99CB432E061FD" modified="2016-01-20" version="1">MPSDRKFAASHITSSTPLLPAINSWEMFLMDQGRSPYTIKAFKGDLQLLASFLPPDATVGSTTTTEINHFLKWLEAGRGVPCSPKSLSRRITSIKSFFRWLQQNGVMVVDPAEKVVQHSVISPLPEVLTPEEELSVVEAALKMRQSRKPDARPYTLLTLLLSTGIKKGECLGIHLNHVDLEAPETAILFIRYANPSSRYKERKISLTPDWVDAYQEYLAQYQPSGQIFPWSPRRLEYLLEEIGNNAGLSKHLSFDMCRWTCALRDWTSGTEYDKIRQKLGISKVQWREVSMKLRRLAGDQPEEALQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y4G9</accession>
    <name>A0A0P6Y4G9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_11045</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76501.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063070.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11045"/>
    <dbReference type="EnsemblBacteria" id="KPL76501">
        <property type="protein sequence ID" value="KPL76501"/>
        <property type="gene ID" value="ADN00_11045"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="4"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="128"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="128"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL76501.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="234" mass="26480" checksum="55ABFCCDD98773AA" modified="2016-01-20" version="1">MCPKVLVVDDDRTLLRFMEEYMRALKFDVISAGGGAEAIRLAYSHQPDLVVMDVMMPGMDGWETTRRLREMSDVPIILLTAKSSEEDKLRGFELGIDDYVTKPFSFAELSARIQAVLNRARHKPAERRNLIPLGARLLDLDRCEVRDGESVILLTPNEFRLLEVLAKSGGRPVSEQELIRQVWGGDSQMDSAAVRRYVWLLRKKLETDPANPKLIMTVRGFGYRLELGASGTEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y6P3</accession>
    <name>A0A0P6Y6P3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_00815</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061049.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL81099">
        <property type="protein sequence ID" value="KPL81099"/>
        <property type="gene ID" value="ADN00_00815"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL81099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="116" mass="13591" checksum="7A816642EBEEB36D" modified="2016-01-20" version="1">MNNPDTDLIFPLRVIPDLADLRGDKWNHLVDQLITPDADRVSQCGFVLMMARLGGCVTCNSDSFRAMRGCTQCAQRTIRRFKGDDEELIKEYEAHREEYRQYLNEQRTKSKHRKRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y6R3</accession>
    <name>A0A0P6Y6R3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_00980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061082.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00980"/>
    <dbReference type="EnsemblBacteria" id="KPL81126">
        <property type="protein sequence ID" value="KPL81126"/>
        <property type="gene ID" value="ADN00_00980"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="6"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL81126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="338" mass="38663" checksum="E7C873CD71EF6906" modified="2016-01-20" version="1">MRKEVVLITGANGEIGHGLIHHLSKHRDVMIVALDVQPLDEKLTHHCHRFIQGDILDQMLLGRLVVEYEIRTIYHLASILSTKAEYNPETAHRINVEGTLNLLRLAVEQSQWQGRPVKFMYPSSIAAYGIPNLQCKEAAGRVKEDEWLAPVTMYGCNKLYCEHLGRYYSRHYRQLAADSGQATIDFRCIRFPGLISAYTIPTGGTSDYAPEMLHAAAQNEDYDCFVREDTRLPFMAMPDAIKSLLMLEEAPRESLSQLIYNVTSFNPTAREIAEIVKGAFPQSQIRFRPHPSRQRIVDSWPADVNDDAAQKDWGWKPDYNQENAFQEYLIPVIQKRYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YAM7</accession>
    <name>A0A0P6YAM7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Helicase_C_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_03315</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061541.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78942">
        <property type="protein sequence ID" value="KPL78942"/>
        <property type="gene ID" value="ADN00_03315"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032830">
        <property type="entry name" value="XPB/Ssl2_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13625">
        <property type="entry name" value="Helicase_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase_C_3" evidence="3">
        <location>
            <begin position="396"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL78942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="555" mass="61645" checksum="90AE65B774D93DBE" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YDF5</accession>
    <name>A0A0P6YDF5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Prephenate/arogenate dehydrogenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01855</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000007">
        <property type="protein sequence ID" value="KPL80039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061262.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000007.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01855"/>
    <dbReference type="EnsemblBacteria" id="KPL80039">
        <property type="protein sequence ID" value="KPL80039"/>
        <property type="gene ID" value="ADN00_01855"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008977">
        <property type="term" value="F:prephenate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004665">
        <property type="term" value="F:prephenate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006571">
        <property type="term" value="P:tyrosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003099">
        <property type="entry name" value="Prephen_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02153">
        <property type="entry name" value="PDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51176">
        <property type="entry name" value="PDH_ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prephenate/arogenate dehydrogenase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="328" mass="35401" checksum="3169E6E8ED84C29E" modified="2016-01-20" version="1">MTIQLTIIGLNQIGLSIGLALSKQTHQLRRVGHDRDSGLHAPAEKMGAVDETRLLLRDSARGADVIVLCQPAAQAIETIEVIIPDLKPECVLLDTSSSPAAFLNAAARLLPANVFALSFVPALHPQYLELNPLDEESAREDLFKDSTIAISSLPSASSDALQLATDLAALLGAQALFADPHEISGLLAASYALPQMAGAALLQAVTTQPGWMEGQKFAGYPFSLATLPFQTQPETQPLAASLLLEKENNLRVLDNYLAALSQLRAMLAEERAADLETWLDDARTARADWLRARRTREYLPASEKIEIPTLGQSFGRLLGLGKRKPKGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GLC1</accession>
    <name>A0A0N8GLC1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_16550</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064151.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16550"/>
    <dbReference type="EnsemblBacteria" id="KPL72082">
        <property type="protein sequence ID" value="KPL72082"/>
        <property type="gene ID" value="ADN00_16550"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3752"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032531">
        <property type="entry name" value="DUF4956"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16316">
        <property type="entry name" value="DUF4956"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="223" mass="24333" checksum="4F1B0BEE1AFC2DFA" modified="2016-01-20" version="1">MDTTVTPPLSLPALLLNLAIGVGLSLVVSWYYVKFGNSLSNRSKFAPILPILTLITLLTITIVKSSLALSLGLVGALSIVRFRTAIKDPEELIFLFFAIAIGLGLGADQRIPTVVSATVILLYLLVRALITRKHNASHSLYLNIQLNTAGGEPATFSQVNQLLAKELKELDLRRLDQSNGNLQITYYLNIQDQDTLVRIMDSLKTAYPESSVSLIEQNNLLGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GLD6</accession>
    <name>A0A0N8GLD6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_15355</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063916.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72202">
        <property type="protein sequence ID" value="KPL72202"/>
        <property type="gene ID" value="ADN00_15355"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="97" mass="11248" checksum="DE8191CA7976BB04" modified="2016-01-20" version="1">MPSVPFMTPPEPEFSFQVGDDVEVFCDHDKEYDRIRGWLKGIVVQVDAKMVAVQFQENVYLTDGWMVPDHILWFPANSPHIREPLKNPPKPRALKLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMS1</accession>
    <name>A0A0N8GMS1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_12115</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063278.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12115"/>
    <dbReference type="EnsemblBacteria" id="KPL76082">
        <property type="protein sequence ID" value="KPL76082"/>
        <property type="gene ID" value="ADN00_12115"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3899"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003959">
        <property type="term" value="F:NADPH dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02932">
        <property type="entry name" value="OYE_YqiM_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044152">
        <property type="entry name" value="YqjM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43303">
        <property type="entry name" value="PTHR43303"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidored_FMN" evidence="1">
        <location>
            <begin position="4"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="354" mass="38820" checksum="4319E107FB800517" modified="2016-01-20" version="1">MPHLFEPFPLRGVTLRNRIGVSPMCQYSYQDGFANDWLLAHLGARAAGGAGLVIAEATAIEPRGRITPYDVGIWSDAQIEPLARVTRFIKAQGAVPGIQIAHAGRKANTDRPWEGGQPISAGDPRWWQTIGPSPLAFSPRHQTPQEMSVQEIQSTQALFRQAARRALDAGFEWLELHAAHGYLIHSFYSPLSNQRADAYGGSFDNRVRFLLETVQTMRAVWPERLPFTVRISGTDWDENGWSVDDSIALAARLKSEGVDLVDCSSGGNLSNASIPFAPHYQVPIAEAVRRGAGIPTAAVGLISDPRLADQIIRQGQADLVLLGRELLRNPTWPIQAAQALEQPAPVPPQYLRAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMS6</accession>
    <name>A0A0N8GMS6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_12345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063319.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76122">
        <property type="protein sequence ID" value="KPL76122"/>
        <property type="gene ID" value="ADN00_12345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="110" mass="12443" checksum="BB965E507C418888" modified="2016-01-20" version="1">MKLDFGTIVTIVVVVLFYVRLMLLQWGKARRLRSLVEREKKKGKSTKKIEAELQKNLGVKVTSMPLITFGLVMILAGGIIRAVPSVPVEYSQYWWMLVTSGVLMSAFAIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GN41</accession>
    <name>A0A0N8GN41_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SBP_bac_5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_10805</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063008.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10805"/>
    <dbReference type="EnsemblBacteria" id="KPL77042">
        <property type="protein sequence ID" value="KPL77042"/>
        <property type="gene ID" value="ADN00_10805"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2639"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002741">
        <property type="entry name" value="MppA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006025814" description="SBP_bac_5 domain-containing protein" evidence="1">
        <location>
            <begin position="27"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="domain" description="SBP_bac_5" evidence="2">
        <location>
            <begin position="163"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="647" mass="69992" checksum="ED2DFB432ED25D14" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNR7</accession>
    <name>A0A0N8GNR7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_06455</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062141.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06455"/>
    <dbReference type="EnsemblBacteria" id="KPL78850">
        <property type="protein sequence ID" value="KPL78850"/>
        <property type="gene ID" value="ADN00_06455"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1794"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03220">
        <property type="entry name" value="ABC_KpsT_Wzt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10147">
        <property type="entry name" value="Wzt_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015860">
        <property type="entry name" value="ABC_transpr_TagH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029439">
        <property type="entry name" value="Wzt_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14524">
        <property type="entry name" value="Wzt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="29"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="61"/>
            <end position="68"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL78850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="418" mass="46288" checksum="5EF85527F4108B19" modified="2016-01-20" version="1">MSAAIEVIHVSKWFRRAKDRPTSLKEAVVKGLQSFKPASKFHALEDVSFSVEPGSMLGIIGENGAGKSTLLRLIGGVGQPNHGTIRVRGRIGALLDLGAGFHPDLTGRENVYISGVITGLTRQQVRERFDEIVDFAELHDFIDSPLRTYSTGMQMRLAFAIAAHIEPEILLVDEVLAVGDLAFQHKCLQRIQRFKQEGVTIVLVSHDISSIRQLCDDVIWLRHGKIEAHGPTEVVVGEYVAEMTAETRKRTPAAQPIDHTTSGIPLVVNQNRFGSQEISITNVVLLGAQGLPASEIDSGDSLTVEIHYQSQNSIERPIFGITLTREDGFVCYDSSSEASSLQINALHDKGVVTLLLDRLDLTGGQYYVDVGIYRQDWSYAYDYHWHVYPLTIRPTKGVKGVIRPPSHWQNTTSSPEDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNS9</accession>
    <name>A0A0N8GNS9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nucleoid-associated protein ADN00_03345</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_03345</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Binds to DNA and alters its conformation. May be involved in regulation of gene expression, nucleoid organization and DNA protection.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the YbaB/EbfC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061547.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03345"/>
    <dbReference type="EnsemblBacteria" id="KPL78946">
        <property type="protein sequence ID" value="KPL78946"/>
        <property type="gene ID" value="ADN00_03345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043590">
        <property type="term" value="C:bacterial nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1310.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00274">
        <property type="entry name" value="DNA_YbaB_EbfC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036894">
        <property type="entry name" value="YbaB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004401">
        <property type="entry name" value="YbaB/EbfC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33449">
        <property type="entry name" value="PTHR33449"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02575">
        <property type="entry name" value="YbaB_DNA_bd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004555">
        <property type="entry name" value="UCP004555"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82607">
        <property type="entry name" value="SSF82607"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00103">
        <property type="entry name" value="DNA_YbaB_EbfC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="116" mass="12234" checksum="C02134139D49870C" modified="2016-01-20" version="1">MAKGFNRMPGGKGMAGGQSGMMQQLKAMQQQMELAQQQLAEETVEATVGGGAVKIVMTGDQVCKSVTIDPELLKDADAEMLQDMMLSAINLGLEKSRKLQQDKMGPVSGGLSGLGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNT1</accession>
    <name>A0A0N8GNT1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SIS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_03450</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PGI/PMI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061569.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03450"/>
    <dbReference type="EnsemblBacteria" id="KPL78962">
        <property type="protein sequence ID" value="KPL78962"/>
        <property type="gene ID" value="ADN00_03450"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004347">
        <property type="term" value="F:glucose-6-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004476">
        <property type="term" value="F:mannose-6-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901135">
        <property type="term" value="P:carbohydrate derivative metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05637">
        <property type="entry name" value="SIS_PGI_PMI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019490">
        <property type="entry name" value="Glu6P/Mann6P_isomerase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10432">
        <property type="entry name" value="bact-PGI_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SIS" evidence="2">
        <location>
            <begin position="36"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="349" mass="38914" checksum="F442D6F049B9E2F1" modified="2016-01-20" version="1">MINDTPERYLQLDVENLYAMIQGLPGQLTRAWKAGMEYALPKAREYRGIVFSGMGASAACADLLAAAVETVCPTPLWVLRGYDLPQWVQGEDILFVALSFSGETEETISAFQQAVERGCTLTAIGQGGTLAEMAREARAPFWQVGEAGRARNLVGWGFGLGLALLHRLGLVPDAEADLRQAVEEMETAQAHFAREKLPAENPAKRMAGQMMGRFNCFFAAEFLEPAARRWKTQVNETAKAWAQMESIPEADHNTLEGVRQPEELLGQTMMVFFQSDLYREENRSRVAITRRMLMLEGLGTDMINARGSSRLAQMWTTVLYGDYVAYYLAIFNGVDPSPVELIRELKEQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNY7</accession>
    <name>A0A0N8GNY7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SGNH_hydro domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_02930</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000013">
        <property type="protein sequence ID" value="KPL79410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02930"/>
    <dbReference type="EnsemblBacteria" id="KPL79410">
        <property type="protein sequence ID" value="KPL79410"/>
        <property type="gene ID" value="ADN00_02930"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013830">
        <property type="entry name" value="SGNH_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036514">
        <property type="entry name" value="SGNH_hydro_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13472">
        <property type="entry name" value="Lipase_GDSL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SGNH_hydro" evidence="1">
        <location>
            <begin position="3"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="200" mass="21496" checksum="F07F591EFD193E51" modified="2016-01-20" version="1">MLALGDSYTVGEGLPAEQSWPAQLSRALEAEDIAVGELRVIARTGWTSEALLSALQEADPQGTYDLVTVMVGVNDQFNSLSIDAYRANLRALIERAVILAGGDAARVIVLSIPDWSASPAGAQFAAQRVPVEVARFNQVCQEEAQRAGTRYVDVTPLSLQMSEREDYSAPDGLHPSGEQYRARVDLILPEARAALGGLDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GP35</accession>
    <name>A0A0N8GP35_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Haloacid dehalogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">ADN00_02190</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000009">
        <property type="protein sequence ID" value="KPL79794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061325.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000009.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02190"/>
    <dbReference type="EnsemblBacteria" id="KPL79794">
        <property type="protein sequence ID" value="KPL79794"/>
        <property type="gene ID" value="ADN00_02190"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
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        <property type="match status" value="1"/>
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    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    </dbReference>
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    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-1278">Translocase</keyword>
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    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
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            <begin position="163"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
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            <begin position="195"/>
            <end position="216"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="10">
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            <end position="250"/>
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        <location>
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            <end position="272"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
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            <end position="431"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
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            <end position="467"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="761"/>
            <end position="778"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="784"/>
            <end position="802"/>
        </location>
    </feature>
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        <location>
            <begin position="6"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="11">
        <location>
            <begin position="74"/>
            <end position="140"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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    </evidence>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
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        <source>
            <dbReference type="ARBA" id="ARBA00023008"/>
        </source>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
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            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="KPL79794.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="811" mass="86539" checksum="F6F39762634401E8" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GPI6</accession>
    <name>A0A0N8GPI6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_00160</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL81002">
        <property type="protein sequence ID" value="KPL81002"/>
        <property type="gene ID" value="ADN00_00160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL81002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="144" mass="16401" checksum="FA32A15EDB7B459E" modified="2016-01-20" version="1">MSDDTKFSLIRPTLNTAFHIDFDWWKNHDNNWRVHLYSCLCEEHQKMYTNTNEESCVDWIDPETAEVHSVDGLQKVLISHCARQAGFITLQTTLVESVFRTLLANGNVPMNSIQLAEVTGKTANTILQTLTGMRVYKGIRPVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GPI7</accession>
    <name>A0A0N8GPI7_9CHLR</name>
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        <recommendedName>
            <fullName evidence="3">HDc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_00215</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="KPL81010">
        <property type="protein sequence ID" value="KPL81010"/>
        <property type="gene ID" value="ADN00_00215"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3437"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
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        <property type="entry name" value="HD_domain"/>
    </dbReference>
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        <property type="entry name" value="HDIG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011624">
        <property type="entry name" value="Metal-dep_PHydrolase_7TM_extra"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011621">
        <property type="entry name" value="Metal-dep_PHydrolase_7TM_intra"/>
    </dbReference>
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        <property type="entry name" value="7TM-7TMR_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07697">
        <property type="entry name" value="7TMR-HDED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00277">
        <property type="entry name" value="HDIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="269"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="300"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
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            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="364"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="391"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="419"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="domain" description="HDc" evidence="3">
        <location>
            <begin position="476"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="696"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="700"/>
            <end position="723"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL81010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="723" mass="80745" checksum="5FA04A0000828B47" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-08-12" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WN64</accession>
    <name>A0A0P6WN64_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_17465</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064332.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL71469">
        <property type="protein sequence ID" value="KPL71469"/>
        <property type="gene ID" value="ADN00_17465"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="9"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL71469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="163" mass="18002" checksum="C4A9671D7FDAF642" modified="2016-01-20" version="1">MSDSNMAGFMIRRAAEQDAPALARLCAQLGYPTEQDVLTPRLAAILERPDQAVFVAAASGGEIIGWLHVLTTQYLESEAFAEIGGIVVDERHRRGGAGRALMQAAEVWAVEQGLRAVRLRSNVIREKAHLFYRSIGYQQVKSQYTFEKELDQARGGRTGTPWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WR89</accession>
    <name>A0A0P6WR89_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Flagellar biosynthesis protein FlhF</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Flagella-associated GTP-binding protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">ADN00_17165</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Necessary for flagellar biosynthesis. May be involved in translocation of the flagellum.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GTP-binding SRP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064278.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17165"/>
    <dbReference type="EnsemblBacteria" id="KPL71420">
        <property type="protein sequence ID" value="KPL71420"/>
        <property type="gene ID" value="ADN00_17165"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044781">
        <property type="term" value="P:bacterial-type flagellum organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020006">
        <property type="entry name" value="FlhF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43134:SF3">
        <property type="entry name" value="PTHR43134:SF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1005">Bacterial flagellum biogenesis</keyword>
    <keyword evidence="7" id="KW-1006">Bacterial flagellum protein export</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AAA" evidence="10">
        <location>
            <begin position="214"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="SRP54" evidence="11">
        <location>
            <begin position="215"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KPL71420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="410" mass="44886" checksum="2BED4B5B569BEC68" modified="2016-01-20" version="1">MTAKTYRAPTMLEALQQVQRDLGTDAIVLSMREVPSGPLWQAWRKPACEVVAASRLDFVNGHNDDAPMRSVSGKQADNNNQLADDAVERILSALQKNGVIQTPVQAGKDSPTNPLAEPHPQLPEFEVRAIKPEAEDLIGAPLKEDSQIPPALARLKKQLTAQGLDRSLIRKLIMNTVQVVNPQVLNNPDRLLSFLQRQLEAGIKSQNQIMLQPPSRVMCMIGTSGSGKTSLCAKLASHYSLTMGKQVVWVSADTFRTAGISEARTYTDAIGVRLRTVYTPEDLREVLKEEQNADLVLVDMPGSNPFDEDEVAEIGGFLSELPGQSLFLVAAATTKESDLAQFVASYGPFRIRGLMITKADETYTFGDAYNLAWRSQLPIYFYTNGHQAVGNLLPGDVDKLVGALFGKGIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WRA9</accession>
    <name>A0A0P6WRA9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_17325</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71447.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064308.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17325"/>
    <dbReference type="EnsemblBacteria" id="KPL71447">
        <property type="protein sequence ID" value="KPL71447"/>
        <property type="gene ID" value="ADN00_17325"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.528"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0807">Transducer</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="326"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="5">
        <location>
            <begin position="347"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="4">
        <location>
            <begin position="465"/>
            <end position="750"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL71447.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="812" mass="85725" checksum="625B67F765942DCF" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WSR3</accession>
    <name>A0A0P6WSR3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Flavodoxin_5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_16275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064180.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16275"/>
    <dbReference type="EnsemblBacteria" id="KPL72041">
        <property type="protein sequence ID" value="KPL72041"/>
        <property type="gene ID" value="ADN00_16275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026816">
        <property type="entry name" value="Flavodoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12724">
        <property type="entry name" value="Flavodoxin_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin_5" evidence="1">
        <location>
            <begin position="7"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="183" mass="20748" checksum="484982FFE66808B0" modified="2016-01-20" version="1">MKENKILVTYATMSGSSQEIAEFVLTELQQQSYAAEIQPCRMVKNLNAFSAVVLGTPLYMFHLHKDALRFLSRHQKALRAMPVALFAGGLYVSNTEEDRQEVQRQMTAELAKFPWLTPSSLLLVGGRFDPDLLRFPYNLIPALKQSEPSDLRDWNAIRDWAHSLPSLFATQTESPVAHARREA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WX86</accession>
    <name>A0A0P6WX86_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">50S ribosomal protein L11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rplK</name>
        <name evidence="11" type="ORF">ADN00_17685</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 8">Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the ribosomal stalk of the 50S ribosomal subunit. Interacts with L10 and the large rRNA to form the base of the stalk. L10 forms an elongated spine to which L12 dimers bind in a sequential fashion forming a multimeric L10(L12)X complex.</text>
    </comment>
    <comment type="PTM">
        <text evidence="6 8">One or more lysine residues are methylated.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the universal ribosomal protein uL11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000043">
        <property type="protein sequence ID" value="KPL70879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064379.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000043.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17685"/>
    <dbReference type="EnsemblBacteria" id="KPL70879">
        <property type="protein sequence ID" value="KPL70879"/>
        <property type="gene ID" value="ADN00_17685"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2127"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070180">
        <property type="term" value="F:large ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00349">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00736">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000911">
        <property type="entry name" value="Ribosomal_L11/L12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036796">
        <property type="entry name" value="Ribosomal_L11/L12_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006519">
        <property type="entry name" value="Ribosomal_L11_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020783">
        <property type="entry name" value="Ribosomal_L11_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036769">
        <property type="entry name" value="Ribosomal_L11_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020785">
        <property type="entry name" value="Ribosomal_L11_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020784">
        <property type="entry name" value="Ribosomal_L11_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11661">
        <property type="entry name" value="PTHR11661"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00298">
        <property type="entry name" value="Ribosomal_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03946">
        <property type="entry name" value="Ribosomal_L11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00649">
        <property type="entry name" value="RL11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46906">
        <property type="entry name" value="SSF46906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54747">
        <property type="entry name" value="SSF54747"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01632">
        <property type="entry name" value="L11_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00359">
        <property type="entry name" value="RIBOSOMAL_L11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0488">Methylation</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6 8" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L11_N" evidence="10">
        <location>
            <begin position="9"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L11" evidence="9">
        <location>
            <begin position="71"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010537"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003978"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL70879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="141" mass="15101" checksum="CB1D1B880CAE9B01" modified="2016-01-20" version="1">MAKKLKAVVKLQITAGKANPAPPIGPALAGHGINIMAFCKEYNARTQNRMGEIIPAEITVYTDGSFTFVLKSSPTAVLLRKAAGIERGSAVPNREKVGKVSRAQVREIAEIKLKDTNAIDIEGAMRQVEGTARNMGIVVED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WXX5</accession>
    <name>A0A0P6WXX5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_16805</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064210.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16805"/>
    <dbReference type="EnsemblBacteria" id="KPL71367">
        <property type="protein sequence ID" value="KPL71367"/>
        <property type="gene ID" value="ADN00_16805"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.421"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003832">
        <property type="entry name" value="DUF212"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31446">
        <property type="entry name" value="PTHR31446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02681">
        <property type="entry name" value="DUF212"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL71367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="153" mass="16705" checksum="5A2DBC0A61EA978C" modified="2016-01-20" version="1">MILQQLANNHMLHAVLIAWFLAQFLKVPMEYLLNHNLNWGLWFSSGGMPSSHSALVTAAVASTGLYSGFDTPAFAVAVALAMVVIYDATGVRRQAGIQAQRINTMISELFMGHPISEERLKEVLGHTPRQVIAGVLLGIAISVSVWLIWPPVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WY09</accession>
    <name>A0A0P6WY09_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Flagellin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_17120</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Flagellin is the subunit protein which polymerizes to form the filaments of bacterial flagella.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Secreted</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Bacterial flagellum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the bacterial flagellin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064269.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17120"/>
    <dbReference type="EnsemblBacteria" id="KPL71413">
        <property type="protein sequence ID" value="KPL71413"/>
        <property type="gene ID" value="ADN00_17120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009288">
        <property type="term" value="C:bacterial-type flagellum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001492">
        <property type="entry name" value="Flagellin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046358">
        <property type="entry name" value="Flagellin_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001029">
        <property type="entry name" value="Flagellin_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42792">
        <property type="entry name" value="PTHR42792"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00700">
        <property type="entry name" value="Flagellin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00669">
        <property type="entry name" value="Flagellin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Flagellin_N" evidence="4">
        <location>
            <begin position="6"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="domain" description="Flagellin_C" evidence="5">
        <location>
            <begin position="220"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005709"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL71413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="302" mass="33448" checksum="DDB71D277BBE6ECD" modified="2016-01-20" version="1">MRVTERMMMDNAIQNMAMNKERLHVLQNKVASGKEFEYASEAPGRASLSMNVRGTLEINESYYTTAKTSHDWVTATEDAFGQMIDAADKAVVLAQKGANDTYGPQERQQMAIEMDGLLKSAIEIGNSTHMGQFIFGGHQIQDKPFSTSMVDTNGDGVLEEVINFDGDAGEMRRDVSPGYTFTINTNGESAFRGFMEALVTARDALNANDNTAIQDALGDLQGAYDQINQFRATNAARQRQLETTMTNLEKTKLQLNAVLNKNEDADMIEAISLMRNQESVFQTVLEVGQRAISAMNLFEVLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZ98</accession>
    <name>A0A0P6WZ98_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Ferrous iron transport protein B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">ADN00_15925</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Probable transporter of a GTP-driven Fe(2+) uptake system.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. FeoB GTPase (TC 9.A.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15925"/>
    <dbReference type="EnsemblBacteria" id="KPL72108">
        <property type="protein sequence ID" value="KPL72108"/>
        <property type="gene ID" value="ADN00_15925"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3618"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015093">
        <property type="term" value="F:ferrous iron transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="P:iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="entry name" value="Fe2_transport_prot-B"/>
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        <property type="entry name" value="Fe2_transport_prot_B_C"/>
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        <property type="entry name" value="FeoB_Cyto"/>
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        <property type="entry name" value="Gate_dom"/>
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        <property type="entry name" value="FeoB_C"/>
        <property type="match status" value="1"/>
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        <property type="match status" value="2"/>
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        <property type="entry name" value="feoB"/>
        <property type="match status" value="1"/>
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    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9" id="KW-0408">Iron</keyword>
    <keyword evidence="9" id="KW-0410">Iron transport</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="154"/>
            <end position="172"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="179"/>
            <end position="204"/>
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    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="224"/>
            <end position="246"/>
        </location>
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    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
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            <end position="284"/>
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    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="290"/>
            <end position="310"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="508"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
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            <end position="566"/>
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            <begin position="350"/>
            <end position="537"/>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
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        <source>
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        <source>
            <dbReference type="RuleBase" id="RU362098"/>
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        <source>
            <dbReference type="Pfam" id="PF07664"/>
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    </evidence>
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        <source>
            <dbReference type="Pfam" id="PF07670"/>
        </source>
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        <source>
            <dbReference type="Pfam" id="PF17910"/>
        </source>
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        <source>
            <dbReference type="EMBL" id="KPL72108.1"/>
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    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="567" mass="62400" checksum="6FD53A64A1DE6EAE" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZZ9</accession>
    <name>A0A0P6WZZ9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_12750</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_LGCL01000027.1"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="KPL75510">
        <property type="protein sequence ID" value="KPL75510"/>
        <property type="gene ID" value="ADN00_12750"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019587">
        <property type="entry name" value="Polyketide_cyclase/dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10604">
        <property type="entry name" value="Polyketide_cyc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL75510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="144" mass="16166" checksum="2F318F0A129287C0" modified="2016-01-20" version="1">MDGKPRVYESAVIAAPREKVWERVRDFNALPVWHPAIAKSELEGGECVGCVRHFFLQDGAELREKLLALSDLDCACVYAILESPMPLKDYVATLRLYEITATKQTFAEWFAYFDVTDPSAEAGTVETVHGVFRTGLESLVKYFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X004</accession>
    <name>A0A0P6X004_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">S-adenosylmethionine synthase</fullName>
            <shortName evidence="11">AdoMet synthase</shortName>
            <ecNumber evidence="11">2.5.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">MAT</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Methionine adenosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">metK</name>
        <name evidence="17" type="ORF">ADN00_14205</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + H2O + L-methionine = diphosphate + phosphate + S-adenosyl-L-methionine</text>
            <dbReference type="Rhea" id="RHEA:21080"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="2.5.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="11">Binds 1 potassium ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="11">Binds 2 divalent ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Amino-acid biosynthesis; S-adenosyl-L-methionine biosynthesis; S-adenosyl-L-methionine from L-methionine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11">Homotetramer; dimer of dimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11 12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11 13">Belongs to the AdoMet synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.6" evidence="11"/>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063693.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000033.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14205"/>
    <dbReference type="EnsemblBacteria" id="KPL74153">
        <property type="protein sequence ID" value="KPL74153"/>
        <property type="gene ID" value="ADN00_14205"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1944"/>
    <dbReference type="UniPathway" id="UPA00315">
        <property type="reaction ID" value="UER00080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004478">
        <property type="term" value="F:methionine adenosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006556">
        <property type="term" value="P:S-adenosylmethionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00086">
        <property type="entry name" value="S_AdoMet_synth1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022631">
        <property type="entry name" value="ADOMET_SYNTHASE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022630">
        <property type="entry name" value="S-AdoMet_synt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022629">
        <property type="entry name" value="S-AdoMet_synt_central"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022628">
        <property type="entry name" value="S-AdoMet_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002133">
        <property type="entry name" value="S-AdoMet_synthetase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022636">
        <property type="entry name" value="S-AdoMet_synthetase_sfam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11964">
        <property type="entry name" value="PTHR11964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02773">
        <property type="entry name" value="S-AdoMet_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02772">
        <property type="entry name" value="S-AdoMet_synt_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00438">
        <property type="entry name" value="S-AdoMet_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000497">
        <property type="entry name" value="MAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55973">
        <property type="entry name" value="SSF55973"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01034">
        <property type="entry name" value="metK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00376">
        <property type="entry name" value="ADOMET_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00377">
        <property type="entry name" value="ADOMET_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 11 12" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 11 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 11" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="10 11 12" id="KW-0630">Potassium</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 11 17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="S-AdoMet_synt_N" evidence="14">
        <location>
            <begin position="5"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="S-AdoMet_synt_M" evidence="15">
        <location>
            <begin position="128"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="S-AdoMet_synt_C" evidence="16">
        <location>
            <begin position="246"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Flexible loop" evidence="11">
        <location>
            <begin position="101"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="19"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="101"/>
        </location>
        <ligand>
            <name>L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="177"/>
            <end position="179"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="243"/>
            <end position="244"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="252"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="258"/>
            <end position="259"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="275"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <note>ligand shared between two neighboring subunits</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="279"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <note>ligand shared between two neighboring subunits</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF02772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF02773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KPL74153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="398" mass="43439" checksum="37ACC75F9B9BB3A6" modified="2016-01-20" version="1">MQSPKYLFTSESVTEGHPDKMCDQISDAVLDACLAQDPRSRVACETATKTGYVIIMGEITTEAFVNFDELVRKIVNEIGYDRGKKGFDGDTCAVLSAISQQSTDIAMGVDKALEAKTGEMTDEEIEKLGAGDQGMMFGYACNETPVLMPMPIYLAHKLTRRLAEVRKNGTLPYLYPDGKSQVTVEYSFGKPVRVPTVVISTQHSADVEQEQIRKDVIEHVIKPIIPTELLDSEAEIYVNPTGRFVIGGPLGDAGLTGRKIIVDTYGGMGRHGGGAFSGKDCTKVDRSAAYAARWVAKNVVAAGLADRCEIQLAYAIGVAHPLSINVETFGTGKVADERIAELIRENFDLRPGAIIRDLDLRKPVYRQVAAYGHFGRDDLDLTWERTNKADALRKAAGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X1L8</accession>
    <name>A0A0P6X1L8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ribose 5-phosphate isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_13405</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LacAB/RpiB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063529.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000031.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13405"/>
    <dbReference type="EnsemblBacteria" id="KPL74830">
        <property type="protein sequence ID" value="KPL74830"/>
        <property type="gene ID" value="ADN00_13405"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1167"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016861">
        <property type="term" value="F:intramolecular oxidoreductase activity, interconverting aldoses and ketoses"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004785">
        <property type="entry name" value="RpiB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003500">
        <property type="entry name" value="RpiB_LacA_LacB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036569">
        <property type="entry name" value="RpiB_LacA_LacB_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02502">
        <property type="entry name" value="LacAB_rpiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005384">
        <property type="entry name" value="RpiB_LacA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89623">
        <property type="entry name" value="SSF89623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01120">
        <property type="entry name" value="rpiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00689">
        <property type="entry name" value="rpiB_lacA_lacB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR005384-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL74830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="145" mass="15658" checksum="7CA525A60FC775F7" modified="2016-01-20" version="1">MKIAIGCDHKAVDLKEIVKKVLTDLGMEVVDLGTQGPERVDYPDYGRAVAEMVAAGGADRGIAICASGVGMSITANKVKGIRAVLCQDSYVARLSRQHNNTNVLCMGALVIGPAVAEEIVRIWLSTDYEGGRHQQRLDKIHQLEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X2J6</accession>
    <name>A0A0P6X2J6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Deaminase/reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062788.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09620"/>
    <dbReference type="EnsemblBacteria" id="KPL76854">
        <property type="protein sequence ID" value="KPL76854"/>
        <property type="gene ID" value="ADN00_09620"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2380"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008703">
        <property type="term" value="F:5-amino-6-(5-phosphoribosylamino)uracil reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002734">
        <property type="entry name" value="RibDG_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01872">
        <property type="entry name" value="RibD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="SSF53597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RibD_C" evidence="1">
        <location>
            <begin position="4"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="190" mass="21136" checksum="D1D9E8E91E2B84E7" modified="2016-01-20" version="1">MARLIYSALSSLDGYIEDADGHFDWAAPDEEVHGFINNLERAAGMYLFGRRMYETMQVWETDPSLAAGSPLLGDFARIWQAAEKIVYSTTLPSPSTRKTRIERTFDPQAIRQMKATTDKDILIGGPNLAAQALRAGLVDEYQLFLAPVIVGGGKACLPNHLRLDLELLEERRFDSGMVFLRYRVKPAAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X2Z5</accession>
    <name>A0A0P6X2Z5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13910</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063633.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000033.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74097">
        <property type="protein sequence ID" value="KPL74097"/>
        <property type="gene ID" value="ADN00_13910"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="106" mass="11844" checksum="C384E9F9D29A2C29" modified="2016-01-20" version="1">MKRKAAADPGRVPGAQPGGDLREEIDMLRGLIQRVVSLAEGGRELEELLGILEKVGRASTRLATLLKTQQTLQNQDDLFDVLNQVIDEVLLEKRADLERKAEQKRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X3W5</accession>
    <name>A0A0P6X3W5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_11870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063231.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76046">
        <property type="protein sequence ID" value="KPL76046"/>
        <property type="gene ID" value="ADN00_11870"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007563">
        <property type="entry name" value="DUF554"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36111">
        <property type="entry name" value="PTHR36111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04474">
        <property type="entry name" value="DUF554"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="188"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="219"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="239" mass="25234" checksum="E212D13DDE8852AB" modified="2016-01-20" version="1">MGTLLNVITIIVGGVLGTFFGDQLPERVRTTVVAGLGLFTTAYGASLFLKSENTLIVVISVLIGALLGEWWQIEEGLKNLGGWLERVLSHGRDRTAESQARFIRGFLTASLVFVIGPMAILGSIQDGLTGDYSTLGVKAILDGFAALAFASSLGVGVIFSFVVILVYQGGITLLAAQMQNFFSTSMMNEMSAVGGVLLLGIGMGSLLELKKIRTGNFLPALAVAPLLVWLLQVLGVTLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X3Y7</accession>
    <name>A0A0P6X3Y7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Anti-sigma factor antagonist</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_12170</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the anti-sigma-factor antagonist family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063288.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12170"/>
    <dbReference type="EnsemblBacteria" id="KPL76092">
        <property type="protein sequence ID" value="KPL76092"/>
        <property type="gene ID" value="ADN00_12170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043856">
        <property type="term" value="F:anti-sigma factor antagonist activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.24">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003658">
        <property type="entry name" value="Anti-sigma_ant"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002645">
        <property type="entry name" value="STAS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036513">
        <property type="entry name" value="STAS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13466">
        <property type="entry name" value="STAS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52091">
        <property type="entry name" value="SSF52091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00377">
        <property type="entry name" value="ant_ant_sig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50801">
        <property type="entry name" value="STAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="STAS" evidence="3">
        <location>
            <begin position="1"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL76092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="111" mass="12111" checksum="44368B25776677F8" modified="2016-01-20" version="1">MNIETKSYKHCDLIEVAGRVDSATAPQLADAINALTDAGHFRIILDFSKLEFISSAGLRVLINAQKNCKRYNRGEVMLTAVPQNVYSALDLAGFTSLFTIKDTVIDAVGSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X470</accession>
    <name>A0A0P6X470_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Signal recognition particle protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Fifty-four homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ffh</name>
        <name evidence="9" type="ORF">ADN00_08245</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in targeting and insertion of nascent membrane proteins into the cytoplasmic membrane. Binds to the hydrophobic signal sequence of the ribosome-nascent chain (RNC) as it emerges from the ribosomes. The SRP-RNC complex is then targeted to the cytoplasmic membrane where it interacts with the SRP receptor FtsY.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the signal recognition particle protein translocation system, which is composed of SRP and FtsY.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="7">The SRP-RNC complex is targeted to the cytoplasmic membrane.</text>
    </comment>
    <comment type="domain">
        <text evidence="7">Composed of three domains: the N-terminal N domain, which is responsible for interactions with the ribosome, the central G domain, which binds GTP, and the C-terminal M domain, which binds the RNA and the signal sequence of the RNC.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the GTP-binding SRP family. SRP54 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062510.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08245"/>
    <dbReference type="EnsemblBacteria" id="KPL77860">
        <property type="protein sequence ID" value="KPL77860"/>
        <property type="gene ID" value="ADN00_08245"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.651"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048500">
        <property type="term" value="C:signal recognition particle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00306">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036891">
        <property type="entry name" value="Signal_recog_part_SRP54_M_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013822">
        <property type="entry name" value="Signal_recog_particl_SRP54_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004125">
        <property type="entry name" value="Signal_recog_particle_SRP54_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004780">
        <property type="entry name" value="SRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022941">
        <property type="entry name" value="SRP54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042101">
        <property type="entry name" value="SRP54_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11564">
        <property type="entry name" value="PTHR11564"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11564:SF7">
        <property type="entry name" value="PTHR11564:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02881">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02978">
        <property type="entry name" value="SRP_SPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00963">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47446">
        <property type="entry name" value="SSF47446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00959">
        <property type="entry name" value="ffh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00300">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0733">Signal recognition particle</keyword>
    <feature type="domain" description="SRP54" evidence="8">
        <location>
            <begin position="266"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="106"/>
            <end position="113"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="187"/>
            <end position="191"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="245"/>
            <end position="248"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL77860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="440" mass="48180" checksum="DE40F9BB7D71A081" modified="2016-01-20" version="1">MFDNLSGRFNEIFQQLRRRGKLSEADVDAVLREVRLALLEADVHYSVVKSFVTRVRERAVGHEVSKALNPAQQVIKIVHEELINTLGEPDRLNLSGPKPRVVMMVGLQGAGKTTATAKLAKILRSQGERVLLVAADPYRPAAVKQLQTLGQQIGVDVYTREGVKPPDLAAQAFDMAQKSGVSAMVIDTAGRSQLDDALMQELQAIARRVPVNETLLTVDSMIGQEALHIAEGFRDSVKLTGLVLTKMDGDSRGGAAISIRSVTGVPIKYLGTGEGLDALESFDPRRLASRILGMGDMIGLIERAEAAFDQQATQDQAQRMLAGQFTLEDFAQQLKQVKKMGPLSQILDMMPGGMGQAARNIDPADAEKQLKRTEAIINSMTVAERKNPDLLNASRRRRIASGSGTDVQDVNRLIKQFRETQRLFKHIKKTGGRGLPRLFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X476</accession>
    <name>A0A0P6X476_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_08305</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="4">Isoprenoid biosynthesis; isopentenyl diphosphate biosynthesis via mevalonate pathway; isopentenyl diphosphate from (R)-mevalonate: step 1/3.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062519.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08305"/>
    <dbReference type="EnsemblBacteria" id="KPL77869">
        <property type="protein sequence ID" value="KPL77869"/>
        <property type="gene ID" value="ADN00_08305"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.663"/>
    <dbReference type="UniPathway" id="UPA00057">
        <property type="reaction ID" value="UER00098"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004496">
        <property type="term" value="F:mevalonate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006205">
        <property type="entry name" value="Mev_gal_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43290">
        <property type="entry name" value="PTHR43290"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08544">
        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="SSF55060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00549">
        <property type="entry name" value="mevalon_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP_kinases_N" evidence="5">
        <location>
            <begin position="93"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP_kinases_C" evidence="6">
        <location>
            <begin position="225"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL77869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="317" mass="33088" checksum="D9DDD34B223EAA91" modified="2016-01-20" version="1">MPAISASAPGKIILFGEHAVVYGQPAIAIPVTQVAARAVVMARPTATSGEVLIDAPDIQTISLLQDLPAEHPLARILRILQAHLGLPAYPAFHLRVTSTIPIAGGMGSGAAVAVAILRAVSAFLNCPLDDATVNKLAFESEKSFHGTPSGVDNTVITYAQPIYFRRGQPFEKLATAAPHTFVIADSGQPGSTAEMVGAVRQRWKTDPRQMETCFEHIGEIVQQARSALESSQTRGLGSLMNKNHSFLQQIGVSTPFLDALVKAALQAGALGAKLSGAGGGGNIIALVETSNAEQVAARLSIAGAVRTIVTTLKPHSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X4I1</accession>
    <name>A0A0P6X4I1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Xanthine permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_11055</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063072.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11055"/>
    <dbReference type="EnsemblBacteria" id="KPL76503">
        <property type="protein sequence ID" value="KPL76503"/>
        <property type="gene ID" value="ADN00_11055"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.906"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015205">
        <property type="term" value="F:nucleobase transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006043">
        <property type="entry name" value="NCS2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00860">
        <property type="entry name" value="Xan_ur_permease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="50"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="74"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="112"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="143"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="171"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="241"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="327"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="358"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="391"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="429"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL76503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="461" mass="47932" checksum="A812FDB5617FA83C" modified="2016-01-20" version="1">MTANGSKKEVFGYMPQDVPPMGAMISLGLQQVLTMFPATILVAILTKFDVGVTLLASGLGTIIALLVSQRKIPMYYGSSFSYITVVVTAMNLYGGGCFADPNTVYCAEGVRIVQVGIMATGVLNILVGLLIMKAGKEALDKVLPPIVTGSMAVVIGIALAGVALGNASTNWLIAFITLVATVVFSVYLQGKGLLGMLPILLGALVGYGVSAATGAIDFGTISSADWVRMPAITLPAFENPQAWGIVFSIALIAIATIPESTAHLYQMSLYIDALAAEMGREPLQIKKLIGLNLVADGVDDMVVGFLGGCAGTNYGENNSLMAITRNYSVPVLMTAGVIAILLGFLGKLAAVVNTIPTAVTGGLSIYLFGVIGMQGVALIQSEKVNLFEPRQLAVGATILILGIGGNLGLPNGIFPLNVPVLFPDGIPAIVFAAIVGILMNLLFVIVPPSLFGVKDRQNINL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X569</accession>
    <name>A0A0P6X569_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ribonuclease Y</fullName>
            <shortName evidence="5">RNase Y</shortName>
            <ecNumber evidence="5">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rny</name>
        <name evidence="8" type="ORF">ADN00_18445</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Endoribonuclease that initiates mRNA decay.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the RNase Y family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="5"/>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064519.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18445"/>
    <dbReference type="EnsemblBacteria" id="KPL70040">
        <property type="protein sequence ID" value="KPL70040"/>
        <property type="gene ID" value="ADN00_18445"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2998"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00335">
        <property type="entry name" value="RNase_Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006675">
        <property type="entry name" value="HDIG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017705">
        <property type="entry name" value="Ribonuclease_Y"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022711">
        <property type="entry name" value="RNase_Y_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12826:SF15">
        <property type="entry name" value="PTHR12826:SF15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12072">
        <property type="entry name" value="RNase_Y_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="SSF54791"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00277">
        <property type="entry name" value="HDIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03319">
        <property type="entry name" value="RNase_Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 5" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="HD" evidence="7">
        <location>
            <begin position="327"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="39"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL70040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="511" mass="57236" checksum="88AFD662F293AF3B" modified="2016-01-20" version="1">MNLTTGQLIIFLLADVVIIGVVIYFVTRLLVERFKRDQASRADNVITEAKEKARSMELEAKDKSLKILEAAENDIARRRNELSREEERLQKRRAELDNRVDRLEQREATLNKRQSTIDRRANEVEKKYQEQAEELQRIAQMTMDEAHTELLALAEKEAQADVARIIRQIEAEARMEGEKRARQLIADAIQRVASDHVSEVCTSVVPLPNEEMKGRIVGRNGRNIRAFEQAAGVDVIVDDTPEAVTVSCFDSVRREIARRALERLIVDGRIHPAHIEKILNEEQREMQRDLIEAGEQAAYDAGVAGLHPEIIKVLGRLKYRTSYGQNQLAHAVESAKLAAVIAAELGANVEVARAGGLLHDLGKAMDHNIEGTHAQIGADYAKRYGVSPAVVNVIASHHHEVEQESVEAVIVEAADAISGARPGARREDLEQYIKRLKALEDIANSFKGVSQSYAIQAGREVRIMVKPDDLDDLAATRLARDIARNIEETMQYPGQIKVTVIRETRAVDYAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5S7</accession>
    <name>A0A0P6X5S7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_06640</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000018">
        <property type="protein sequence ID" value="KPL78399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062195.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000018.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78399">
        <property type="protein sequence ID" value="KPL78399"/>
        <property type="gene ID" value="ADN00_06640"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="72" mass="8252" checksum="D3A0CCB4890F8F71" modified="2016-01-20" version="1">MGKFKEPDSNSFEEPGESNQDKSGAKNLPERVDFDHSMSIDEILDVIEKMSDDYKKSKAKQNDEKEGKENKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X6W9</accession>
    <name>A0A0P6X6W9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-acetylneuraminate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_11995</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063254.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11995"/>
    <dbReference type="EnsemblBacteria" id="KPL76063">
        <property type="protein sequence ID" value="KPL76063"/>
        <property type="gene ID" value="ADN00_11995"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3875"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016051">
        <property type="term" value="P:carbohydrate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013132">
        <property type="entry name" value="Neu5Ac_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03102">
        <property type="entry name" value="NeuB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NeuB" evidence="1">
        <location>
            <begin position="38"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="295" mass="33090" checksum="D2EA43188A7B3BCD" modified="2016-01-20" version="1">MPKAVKLGNRWVGEGYPTYIIGEIGINHNGDLDVAKELIREAKEAGLDAVKFQKRTPAICVPPEQQGQMRETPWGYITYLDYRYKVEFEAEQYAEIDRYCKELGIDWFASVWDEPAVDFLEQFNPVCYKVPSASLTDHGLLRKLRATGRPVILSTGMSTMEEIREAITVIGLENLLITHTTSAYPCDPSELNLRMIQSLMDEFPVPIGYSGHEVGLVPSAIAVALGACLVERHITLDRAMWGNDQAASVEPGGFRKLVKYIRVTEESLGDGVKKVYDSELSSLKKLRRFRPSSQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X6Y8</accession>
    <name>A0A0P6X6Y8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">PMT_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ADN00_12110</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063277.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12110"/>
    <dbReference type="EnsemblBacteria" id="KPL76081">
        <property type="protein sequence ID" value="KPL76081"/>
        <property type="gene ID" value="ADN00_12110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038731">
        <property type="entry name" value="RgtA/B/C-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13231">
        <property type="entry name" value="PMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="120"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="144"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="175"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="202"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="247"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="311"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="336"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="364"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="394"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="domain" description="PMT_2" evidence="9">
        <location>
            <begin position="115"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL76081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="550" mass="62713" checksum="8B507435DC3F5A9B" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X774</accession>
    <name>A0A0P6X774_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_18130</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL69989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064458.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL69989">
        <property type="protein sequence ID" value="KPL69989"/>
        <property type="gene ID" value="ADN00_18130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13098">
        <property type="entry name" value="Thioredoxin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="2">
        <location>
            <begin position="35"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL69989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="154" mass="17510" checksum="4A6542F6900BA136" modified="2016-01-20" version="1">MSANENQKQTTFQKKGWKNWLILAGILLVVAVVFVLKNQSSPVDTAANLSPEEQLDIYLEDKEPIFLFFHSDNCHSCIVMMETVDDVFPEFKDRVKMVDVNVYDPQNQDLLRKAQIYSIPTQIFIDQEAKGKVAMGVMSAEELREQLQILAGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X779</accession>
    <name>A0A0P6X779_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_17915</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000043">
        <property type="protein sequence ID" value="KPL70909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064412.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000043.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17915"/>
    <dbReference type="EnsemblBacteria" id="KPL70909">
        <property type="protein sequence ID" value="KPL70909"/>
        <property type="gene ID" value="ADN00_17915"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2165"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070063">
        <property type="term" value="F:RNA polymerase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032784">
        <property type="term" value="P:regulation of DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036953">
        <property type="entry name" value="GreA/GreB_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029462">
        <property type="entry name" value="Rnk_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001437">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023459">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30437">
        <property type="entry name" value="PTHR30437"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01272">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14760">
        <property type="entry name" value="Rnk_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rnk_N" evidence="2">
        <location>
            <begin position="6"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="GreA_GreB" evidence="1">
        <location>
            <begin position="53"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL70909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="136" mass="14904" checksum="EC9A36BD3BC4F991" modified="2016-01-20" version="1">MYNHTIHITQADAAKLRDLIRDTHIPGEALNPHLAALNAELDRAVIIDSREIPADVITMNSQAHLEDMETGEEMHFSLVFPESADSQQGKISILAPVGTATLGYRAGDVFEMQTPGGVRKLKIVRVLYQPEASGDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X780</accession>
    <name>A0A0P6X780_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Lipoyl-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_18190</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GcvH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL69998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064471.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18190"/>
    <dbReference type="EnsemblBacteria" id="KPL69998">
        <property type="protein sequence ID" value="KPL69998"/>
        <property type="gene ID" value="ADN00_18190"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2941"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005960">
        <property type="term" value="C:glycine cleavage complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019464">
        <property type="term" value="P:glycine decarboxylation via glycine cleavage system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06848">
        <property type="entry name" value="GCS_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002930">
        <property type="entry name" value="GCV_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033753">
        <property type="entry name" value="GCV_H/Fam206"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11715">
        <property type="entry name" value="PTHR11715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01597">
        <property type="entry name" value="GCV_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="3">
        <location>
            <begin position="35"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL69998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="149" mass="16656" checksum="3E0068F13FCC1D7A" modified="2016-01-20" version="1">MPEYLETQVDKFFFKVATDRLYSREGVWVKKEGASVQVGLTDYLQQLSGDIAFADVKPVGTEVTPGDEVASIETIKVDAVIHSPIHGKINLVNPKMQSEPEAINQDPYGEGWLCQLEVTDWEEDSVHLLAPDAYFVIMKAEAEEEAKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X790</accession>
    <name>A0A0P6X790_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">GDP-L-fucose synthase</fullName>
            <ecNumber evidence="2">1.1.1.271</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">GDP-4-keto-6-deoxy-D-mannose-3,5-epimerase-4-reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">fcl</name>
        <name evidence="4" type="ORF">ADN00_12095</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the two-step NADP-dependent conversion of GDP-4-dehydro-6-deoxy-D-mannose to GDP-fucose, involving an epimerase and a reductase reaction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>GDP-beta-L-fucose + NADP(+) = GDP-4-dehydro-alpha-D-rhamnose + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:18885"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57273"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57964"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.271"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Nucleotide-sugar biosynthesis; GDP-L-fucose biosynthesis via de novo pathway; GDP-L-fucose from GDP-alpha-D-mannose: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the NAD(P)-dependent epimerase/dehydratase family. Fucose synthase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.271" evidence="2"/>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12095"/>
    <dbReference type="EnsemblBacteria" id="KPL76173">
        <property type="protein sequence ID" value="KPL76173"/>
        <property type="gene ID" value="ADN00_12095"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00128">
        <property type="reaction ID" value="UER00191"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050577">
        <property type="term" value="F:GDP-L-fucose synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070401">
        <property type="term" value="F:NADP+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042351">
        <property type="term" value="P:'de novo' GDP-L-fucose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd05239">
        <property type="entry name" value="GDP_FS_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00956">
        <property type="entry name" value="GDP_fucose_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028614">
        <property type="entry name" value="GDP_fucose/colitose_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="3">
        <location>
            <begin position="11"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="2">
        <location>
            <position position="140"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="14"/>
            <end position="20"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="167"/>
            <end position="170"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="2">
        <location>
            <position position="111"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="2">
        <location>
            <position position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL76173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="312" mass="35083" checksum="4907F14531903213" modified="2016-01-20" version="1">MTNFWSERRFCVTGGAGFLGKVVVRKLQERGAKEVFVPTIDRYDLVDRESICQMLDDARPDVIIHLAAHVGGIGANREHPAEFFYDNLMMGVQLMHEAWKRGVEKFVAIGTVCAYPKFTPVPFSEDDLWIGYPEETNAPYGLAKKMLLVQSQAYRQQYGFNSIFLLPVNLYGPGDNFNPASSHVIPALIRKCVEAQAAGTKEIVVWGDGSPTREFLFVEDAAEGILMATEKYNESDPVNLGSGYEISIKDLAEMIAAKVGFEGQLVWDTTKPNGQPRRALNTSRAWERFGFRAKVDFDEGLQKTIAWYRENH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7F2</accession>
    <name>A0A0P6X7F2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA-directed RNA polymerase subunit beta'</fullName>
            <shortName evidence="7">RNAP subunit beta'</shortName>
            <ecNumber evidence="7">2.7.7.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">RNA polymerase subunit beta'</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Transcriptase subunit beta'</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rpoC</name>
        <name evidence="11" type="ORF">ADN00_08385</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7 8">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="7">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 2 Zn(2+) ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7 8">Belongs to the RNA polymerase beta' chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="7"/>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062535.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08385"/>
    <dbReference type="EnsemblBacteria" id="KPL77884">
        <property type="protein sequence ID" value="KPL77884"/>
        <property type="gene ID" value="ADN00_08385"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.679"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.860.120">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="DNA-dir_RpoC_beta_prime"/>
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        <property type="entry name" value="DNA-dir_RpoC_beta_prime_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000722">
        <property type="entry name" value="RNA_pol_asu"/>
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        <property type="entry name" value="RNA_pol_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007080">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
    </dbReference>
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        <property type="entry name" value="RNA_pol_Rpb1_3"/>
    </dbReference>
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        <property type="entry name" value="RNA_pol_Rpb1_3_sf"/>
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    <dbReference type="InterPro" id="IPR007081">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044893">
        <property type="entry name" value="RNA_pol_Rpb1_clamp_domain"/>
    </dbReference>
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        <property type="entry name" value="Rpb1_funnel_sf"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04997">
        <property type="entry name" value="RNA_pol_Rpb1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00623">
        <property type="entry name" value="RNA_pol_Rpb1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04983">
        <property type="entry name" value="RNA_pol_Rpb1_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05000">
        <property type="entry name" value="RNA_pol_Rpb1_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04998">
        <property type="entry name" value="RNA_pol_Rpb1_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00663">
        <property type="entry name" value="RPOLA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02386">
        <property type="entry name" value="rpoC_TIGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 7 8" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 7 8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 7 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="RPOLA_N" evidence="10">
        <location>
            <begin position="402"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="147"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="253"/>
            <end position="317"/>
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    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="59"/>
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        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
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        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
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    <feature type="binding site" evidence="7">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="627"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="629"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="631"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="967"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="1040"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="1047"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
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        <location>
            <position position="1050"/>
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        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
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        <source>
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        </source>
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        <source>
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        </source>
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        </source>
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        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00024550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL77884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="1414" mass="159641" checksum="239E8EA135A506D2" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7M7</accession>
    <name>A0A0P6X7M7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_18115</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18115"/>
    <dbReference type="EnsemblBacteria" id="KPL70163">
        <property type="protein sequence ID" value="KPL70163"/>
        <property type="gene ID" value="ADN00_18115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002143">
        <property type="term" value="P:tRNA wobble position uridine thiolation"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DsrEFH-like"/>
    </dbReference>
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        <property type="entry name" value="Sulphur_relay_TusB/DsrH"/>
    </dbReference>
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        <property type="entry name" value="PTHR37526"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04077">
        <property type="entry name" value="DsrH"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF75169"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03011">
        <property type="entry name" value="sulf_tusB_dsrH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="73" mass="8349" checksum="566160D75B073AB9" modified="2016-01-20" version="1">METTDESDSIVLIQNGVFWAISEEIDPFINHRNIFALKPDFIARGYQESDSKVPLIDYSDLVDLIEKNEKSMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X8Y5</accession>
    <name>A0A0P6X8Y5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 14">Undecaprenyl-diphosphatase</fullName>
            <ecNumber evidence="4 14">3.6.1.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13 14">Bacitracin resistance protein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12 14">Undecaprenyl pyrophosphate phosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">uppP</name>
        <name evidence="15" type="ORF">ADN00_11710</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Catalyzes the dephosphorylation of undecaprenyl diphosphate (UPP). Confers resistance to bacitracin.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>di-trans,octa-cis-undecaprenyl diphosphate + H2O = di-trans,octa-cis-undecaprenyl phosphate + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:28094"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58405"/>
            <dbReference type="ChEBI" id="CHEBI:60392"/>
            <dbReference type="EC" id="3.6.1.27"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="14">Cell membrane</location>
            <topology evidence="14">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="14">Bacitracin is thought to be involved in the inhibition of peptidoglycan synthesis by sequestering undecaprenyl diphosphate, thereby reducing the pool of lipid carrier available.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the UppP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.27" evidence="4 14"/>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063201.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11710"/>
    <dbReference type="EnsemblBacteria" id="KPL76021">
        <property type="protein sequence ID" value="KPL76021"/>
        <property type="gene ID" value="ADN00_11710"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3817"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050380">
        <property type="term" value="F:undecaprenyl-diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016311">
        <property type="term" value="P:dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01006">
        <property type="entry name" value="Undec_diphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003824">
        <property type="entry name" value="UppP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30622">
        <property type="entry name" value="PTHR30622"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02673">
        <property type="entry name" value="BacA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00753">
        <property type="entry name" value="undec_PP_bacA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 14" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="6 14" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="14" id="KW-0133">Cell shape</keyword>
    <keyword evidence="14" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="8 14" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="90"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="118"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="192"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="222"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="255"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010621"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00021581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00032707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00032932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KPL76021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="275" mass="30049" checksum="AED38BDF504BE6F4" modified="2016-01-20" version="1">MTVLQSIILGFIQGLTEFLPISSSGHLVLIPHLFGWELDPDFVFIFDVLVQMGTLVAVILYYRSHLWKIASAFLNSLKTRQPFAEQDSRLGWCLILATLPGVTIALIINGVVETAFKSPLMVAGFLFLTAGLLVLSEQAGKQTRRMEQLKAVDALWIGLAQALSIFPGVSRSGATISGGMLRGLDRKDSADFSFLMSIPIMIGAGVYSLADLAQTPALFTYLPQLASGFITAAVVGYLSIAWLLRFLKKQSLKWFALYCALMGSLVLILEYATSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X8Z5</accession>
    <name>A0A0P6X8Z5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_02925</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000013">
        <property type="protein sequence ID" value="KPL79396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061459.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000013.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79396">
        <property type="protein sequence ID" value="KPL79396"/>
        <property type="gene ID" value="ADN00_02925"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031415">
        <property type="term" value="C:NatA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004596">
        <property type="term" value="F:peptide alpha-N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006474">
        <property type="term" value="P:N-terminal protein amino acid acetylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045047">
        <property type="entry name" value="Ard1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23091">
        <property type="entry name" value="PTHR23091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="3">
        <location>
            <begin position="6"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL79396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="150" mass="17456" checksum="4903901087CD6C87" modified="2016-01-20" version="1">MDETHWLIEPANWRDLPALQRLERVCFDVDAWSLLDLAGVLSLPDYTHFKASIDGRLAGFVAAEQRREETKAWIITIGVFPEYRRLGIARALLNEIEARIHLPVVRLCVRRSNLAAQHLYESSGYRAIDIWRHYYHSGEDAQVYEKILHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X981</accession>
    <name>A0A0P6X981_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_17945</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000043">
        <property type="protein sequence ID" value="KPL70912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064416.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000043.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70912">
        <property type="protein sequence ID" value="KPL70912"/>
        <property type="gene ID" value="ADN00_17945"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="203" mass="21980" checksum="57EEB1EE5F785752" modified="2016-01-20" version="1">MITCPWCGTSFLSFKPNCTNCGGPMPLPAPERPSGAAILPPPAPPRPISDRYVWKLVLVDGWAIAGFVFSLLGAIFSVIGLALTLGVITAFVGIPFALLGLVFLGGGVALAFWRYTEKQKIVNVLKWGSAALGVINTVEQNFTVRINQRHPWQIDYQFQSGGQTLNGQVSTLSQPGPQFQPGQQVYVLYMPGEPQLNALYPHP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9C6</accession>
    <name>A0A0P6X9C6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_09595</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062783.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09595"/>
    <dbReference type="EnsemblBacteria" id="KPL76849">
        <property type="protein sequence ID" value="KPL76849"/>
        <property type="gene ID" value="ADN00_09595"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="183" mass="19926" checksum="8307041A6FCB854F" modified="2016-01-20" version="1">MKKQKEVFELRIESLRVLGEWAAACAERALPIYEELNQGDPRPRAAIDGIRIFARGGKRSAQLRVLALDAFRAAHAAKDPAASAAAQAASLAAASAYTHPLVDVQQTGHIVGPAAYAALAIEIDNQHDPLLGNAEVRRAIEQAPFEICEILLNMPARTAGKSRLDKMMYELDRGLRDKFPKMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9Y0</accession>
    <name>A0A0P6X9Y0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HPr domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_11305</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063121.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11305"/>
    <dbReference type="EnsemblBacteria" id="KPL76542">
        <property type="protein sequence ID" value="KPL76542"/>
        <property type="gene ID" value="ADN00_11305"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00367">
        <property type="entry name" value="PTS-HPr_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000032">
        <property type="entry name" value="HPr-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035895">
        <property type="entry name" value="HPr-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001020">
        <property type="entry name" value="PTS_HPr_His_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002114">
        <property type="entry name" value="PTS_HPr_Ser_P_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00381">
        <property type="entry name" value="PTS-HPr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00107">
        <property type="entry name" value="PHOSPHOCPHPR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55594">
        <property type="entry name" value="SSF55594"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01003">
        <property type="entry name" value="PTS_HPr_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51350">
        <property type="entry name" value="PTS_HPR_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00369">
        <property type="entry name" value="PTS_HPR_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00589">
        <property type="entry name" value="PTS_HPR_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0598">Phosphotransferase system</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HPr" evidence="4">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL76542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="89" mass="9434" checksum="99B2C735D5F5D41D" modified="2016-01-20" version="1">MPEITLTINNKVGLHARPASIFVREASKFKSTIKVRNGAREANAKSILNVLTLGADMGSVITISAEGEDAEQALQALQALHASNFGEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XA17</accession>
    <name>A0A0P6XA17_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HPr domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_11535</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063164.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11535"/>
    <dbReference type="EnsemblBacteria" id="KPL76579">
        <property type="protein sequence ID" value="KPL76579"/>
        <property type="gene ID" value="ADN00_11535"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00367">
        <property type="entry name" value="PTS-HPr_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000032">
        <property type="entry name" value="HPr-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035895">
        <property type="entry name" value="HPr-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00381">
        <property type="entry name" value="PTS-HPr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00107">
        <property type="entry name" value="PHOSPHOCPHPR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55594">
        <property type="entry name" value="SSF55594"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01003">
        <property type="entry name" value="PTS_HPr_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51350">
        <property type="entry name" value="PTS_HPR_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HPr" evidence="1">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="89" mass="9796" checksum="B2D7DE930BCD5F2D" modified="2016-01-20" version="1">MMEAEIQVKHEHGLHARPADLFVRTANRFQSNIQVVNMTTGSNLVNAKSIIRILGLGVCKDHKIRLIAEGSDEAEAITALTDLIANNFN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAQ6</accession>
    <name>A0A0P6XAQ6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Epimerase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79219.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061874.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79219">
        <property type="protein sequence ID" value="KPL79219"/>
        <property type="gene ID" value="ADN00_05100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79219.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="339" mass="36639" checksum="9EFD8DA7D2E58919" modified="2016-01-20" version="1">MKALVTGSTGFIGGAICRRLVEQGVQVRAFHRETSSLKLLADLPVEHALGDLTQPETLEAAVQDVDVVFHAAALLGGREDPGRMYTVTVEGTRALLKAARKAGVRRLVYTSSVAALGVPEVSRLHPPVRGLLDENHAWNCPPAIWPYGYSKYLAELEVQKAVAGGLDAVIVNPALVFGPGDVYRKTSSVVVQVASGKLRLSVEGGVNVVHIEDVVSGHLAALEHGRRGARYILAGTNLPLPEMTRAIAELSGMPVPFVVPGRVVRLSAGLLKRLEDFLPLPVSAEMLNLAGHYFYYDGRKAQRELRLEAPLPARRALKDAYDWFVSEGVIRPRQNKAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAR2</accession>
    <name>A0A0P6XAR2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5 family acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09615</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062787.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76853">
        <property type="protein sequence ID" value="KPL76853"/>
        <property type="gene ID" value="ADN00_09615"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2379"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="6"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="172" mass="18174" checksum="8A58B8362D882CA2" modified="2016-01-20" version="1">MTIPNLLIRDETQADAAAISDVTIAAFETLEISSHTEQFIVTALRRAGALSLSLVAELDGRVVGHIAFSPVTMSDGTSGWYGLGPVSVLPELQRAGIGKALIRAGLARLKEMGARGCCLVGHPDYYRKFGFENADGLALEGVPPEVFFALSFDGHIPQGTVTFHEGFAAAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAR3</accession>
    <name>A0A0P6XAR3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09315</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09315"/>
    <dbReference type="EnsemblBacteria" id="KPL77316">
        <property type="protein sequence ID" value="KPL77316"/>
        <property type="gene ID" value="ADN00_09315"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="190"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="227"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="249"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="290"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="313"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="373" mass="42723" checksum="C66AC396199636B4" modified="2016-01-20" version="1">MAEALLIRKLDFKKLFFADLFSRIFAYTIVSIFLAIKGFGEWSLVGGTIISTFIRSIYLLYSAKTRLKFIIRKREFLELFSFGGMYSLLRVINYFAQKADNFVVGRYLGVDTLGLYDRAFQIMSYPGMLIGNVLDGTMFPSMSIVQNQPERLKNAYYRSLSLVNIILMPLSIFLVLNAPEIIKILLGKPWMGLVNPLQVLFLVIPLRSSSRMCDSLARAKGALSQNALQKLIYLFVITLGSFFGKRYGLVGVAWGVNFAVIVHFLLMSYLGETLIGGKAIKILVTFKEGLHYSLIVFVVCGFSLLMLRMFIEYAIITLIIEMIVLMVVFWVICQVFPRFFGDDLRWFIRNLIFAVPNTKVRLRLMNFSRMEIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBP7</accession>
    <name>A0A0P6XBP7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">4-alpha-glucanotransferase</fullName>
            <ecNumber evidence="3 7">2.4.1.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5 7">Amylomaltase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6 7">Disproportionating enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_15180</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>Transfers a segment of a (1-&gt;4)-alpha-D-glucan to a new position in an acceptor, which may be glucose or a (1-&gt;4)-alpha-D-glucan.</text>
            <dbReference type="EC" id="2.4.1.25"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the disproportionating enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.25" evidence="3 7"/>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063884.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15180"/>
    <dbReference type="EnsemblBacteria" id="KPL72174">
        <property type="protein sequence ID" value="KPL72174"/>
        <property type="gene ID" value="ADN00_15180"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.738"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004134">
        <property type="term" value="F:4-alpha-glucanotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102500">
        <property type="term" value="F:beta-maltose 4-alpha-glucanotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003385">
        <property type="entry name" value="Glyco_hydro_77"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32438">
        <property type="entry name" value="PTHR32438"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02446">
        <property type="entry name" value="Glyco_hydro_77"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00217">
        <property type="entry name" value="malQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7 8" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005684"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00020295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL72174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="503" mass="58152" checksum="952DA4FA7C2277B3" modified="2016-01-20" version="1">MKFNRSSGILLHPTSLPGPDGIGDLGPEAFRWINFMADTGCALWQVLPLGPTGYGDSPYQCFSAFAGNPYLVNPFLLQEDHLLTAEDLKDRPTFPEDRVDFGQAILWKLKLLDTASANFKRNASAELRQEYEEFLAENQDWLPDFTLFMAIKENFGGVSWDKWPKELRKRDAIALAEFKYNHAESIQRHSLRQFFFFRQWDAVRQYAKEKNIQIVGDIPIFVAYDSADAWANPDLFYFDEKGLPTVVAGVPPDYFSPTGQLWGNPLYRWDFHEKTGYEWWLKRIKATLKTVDFIRLDHFRGFAGYWEVPFGMPTAEIGRWVKGPGKKFFQKVRNELGDLPIIAEDLGEITPDVVEMRDEFGLPGMRILQFAFASDSTDPFLPHNYVENCVAYTGTHDNDTVIGWYQSGTDQEKDFYRRYMARSGEDVAWDLVRGVWSSVAVFSLAPLQDLLRLGNEARMNYPGRPSGNWTWRVRPDYITPAFLQSIREINRLYSRMNKEKIHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBR9</accession>
    <name>A0A0P6XBR9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fe-S cluster assembly protein SufB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_15345</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0051 (ycf24) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063915.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15345"/>
    <dbReference type="EnsemblBacteria" id="KPL72201">
        <property type="protein sequence ID" value="KPL72201"/>
        <property type="gene ID" value="ADN00_15345"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.771"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010231">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000825">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037284">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045595">
        <property type="entry name" value="SufBD_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01458">
        <property type="entry name" value="SUFBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19295">
        <property type="entry name" value="SufBD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101960">
        <property type="entry name" value="SSF101960"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01980">
        <property type="entry name" value="sufB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SufBD_N" evidence="2">
        <location>
            <begin position="132"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF19295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL72201.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="470" mass="52887" checksum="2C8C06BEE0E6ABF0" modified="2016-01-20" version="1">MSSKPPVDFLSDLEQYQYGFRDPETYVFKSRKGLDREVVEQISAHKGEPQWMLDFRLKALEHFRTRPMPNWGPDISGLNLDDIFYYVRPAEMESKSWDDVPDTIKKTFDRLGIPEAEQRFLAGVGAQYESEMVYHNVQEKLKQQGVIFVSIEDGLRHHEELFREYFGKIIPIEDNKFAALNSAVWSGGSFVYIPKGLKVEMPLQAYFRLNVANIGQFERTLIIADEGAQVHYVEGCTAPQYTTDSFHSGVIEIVVKKNARVRYSTIQNWSNNVYNLVTQRAMVDEGGTMEWVDANIGSKVTMKYPSCYLMGEGAHGEILSMAFAGPGQIQDAGGKMLHFAPNTSSKITSKSISKGGGRASYRGLLKVHPNAGNVKSNVVCDALIMDPDSQTDTYPYIEIEEENVTIGHEASVSKVGEEQLFYLMSRGLSEEEAQTMVVSGFIEPLVKELPMEYAVEMNRLIQLQMEGSVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XC40</accession>
    <name>A0A0P6XC40_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_08000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062465.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08000"/>
    <dbReference type="EnsemblBacteria" id="KPL77819">
        <property type="protein sequence ID" value="KPL77819"/>
        <property type="gene ID" value="ADN00_08000"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL77819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="114" mass="12847" checksum="7788A1690160443A" modified="2016-01-20" version="1">MSDQNTGYPKRKIFICSNGSCIDSSVSRDIYAQLTSLIQEHGLDSFDAPRQVKCALSGCLDRCINGPVMVVHPDGIWYERVTPQVLAQIFNQHILHDQPVEEYIFRKSKPAGDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDM9</accession>
    <name>A0A0P6XDM9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">LytR_cpsA_psr domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_00745</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LytR/CpsA/Psr (LCP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00745"/>
    <dbReference type="EnsemblBacteria" id="KPL81087">
        <property type="protein sequence ID" value="KPL81087"/>
        <property type="gene ID" value="ADN00_00745"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004474">
        <property type="entry name" value="LytR_CpsA_psr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03816">
        <property type="entry name" value="LytR_cpsA_psr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00350">
        <property type="entry name" value="lytR_cpsA_psr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LytR_cpsA_psr" evidence="2">
        <location>
            <begin position="43"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL81087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="277" mass="30586" checksum="9A4200C450180820" modified="2016-01-20" version="1">MGPLGCLLTGFLLLALLYLIAPIRTNILLLGVDRTPDGTALGRTDTMILVSVNPLLPTVNWLSIPRDLWVAIPGYGENRINTAHFFAEAETPGSGPTLSRRTIEQNFGIRVPYYIRIQFDGFKNVVNAMGGVTVRLDEPMAGYPVGSHHLDADQSLAFVRDRKGADDFFRMKNTQVFLKSAILQGISPASWPRYPAIFSAVFQAIKTNLPVWEWPRISLALIRASVTGMNTQTITREMVTPWTTSEGANVLLPDYGQINALMKEMFSSGFSLDSILP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDQ9</accession>
    <name>A0A0P6XDQ9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aldehyde oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_00280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060954.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00280"/>
    <dbReference type="EnsemblBacteria" id="KPL81020">
        <property type="protein sequence ID" value="KPL81020"/>
        <property type="gene ID" value="ADN00_00280"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3449"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000674">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036856">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016208">
        <property type="entry name" value="Ald_Oxase/xanthine_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008274">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037165">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11908">
        <property type="entry name" value="PTHR11908"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01315">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02738">
        <property type="entry name" value="Ald_Xan_dh_C2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01008">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54665">
        <property type="entry name" value="SSF54665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56003">
        <property type="entry name" value="SSF56003"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ald_Xan_dh_C" evidence="1">
        <location>
            <begin position="18"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL81020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="739" mass="79830" checksum="F138FAE635929714" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDV9</accession>
    <name>A0A0P6XDV9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PPC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_08530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062562.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08530"/>
    <dbReference type="EnsemblBacteria" id="KPL77904">
        <property type="protein sequence ID" value="KPL77904"/>
        <property type="gene ID" value="ADN00_08530"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11378">
        <property type="entry name" value="DUF296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005175">
        <property type="entry name" value="PPC_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03479">
        <property type="entry name" value="PCC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51742">
        <property type="entry name" value="PPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPC" evidence="1">
        <location>
            <begin position="1"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="135" mass="14850" checksum="EFE54DB6E0D4D0BE" modified="2016-01-20" version="1">MKTYVLRLHPGQDLRLELVKFAQENDIQAGFIISCVGSLKRAALRMAGQFGPVASFFEEKFEILSLVGTISPDKPHLHIALSNADAKMVGGHLQGGSLVDLTAEIIIGDLEDKVFRRELDTQTGFPELVVYPRGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDZ7</accession>
    <name>A0A0P6XDZ7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cysteine desulfurase</fullName>
            <ecNumber evidence="4">2.8.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_06805</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[sulfur carrier]-H + L-cysteine = [sulfur carrier]-SH + L-alanine</text>
            <dbReference type="Rhea" id="RHEA:43892"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="EC" id="2.8.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 5">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.7" evidence="4"/>
    <dbReference type="EMBL" id="LGCL01000018">
        <property type="protein sequence ID" value="KPL78440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062242.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000018.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06805"/>
    <dbReference type="EnsemblBacteria" id="KPL78440">
        <property type="protein sequence ID" value="KPL78440"/>
        <property type="gene ID" value="ADN00_06805"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2274"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031071">
        <property type="term" value="F:cysteine desulfurase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006534">
        <property type="term" value="P:cysteine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06453">
        <property type="entry name" value="SufS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010969">
        <property type="entry name" value="Cys_dSase-rel_unknwn_funct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010970">
        <property type="entry name" value="Cys_dSase_SufS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016454">
        <property type="entry name" value="Cysteine_dSase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005572">
        <property type="entry name" value="NifS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01977">
        <property type="entry name" value="am_tr_V_EF2568"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotran_5" evidence="6">
        <location>
            <begin position="2"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL78440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="382" mass="41063" checksum="65DFF2E957F0593A" modified="2016-01-20" version="1">MIYLDHPATSWPKPPEVAAAMLNFLQNVGANPGRSGHRLSVEAARIVFAAREAVAELFGCEDALRVVFGANVTWALNQALHGYLRAGDHVITSGMEHNSMMRPLRDLERQGVEVSVVPCGQAGRLDAQRVEDALRDNTVMVALNHASNVSGTILPVREVGEITRRRGIMLLVDAAQTGGTLPVDMRRDQIDLLAFTGHKGLLGPMGTGGLILGERVDLGRLRPVLQGGTGSRSESEIHPDFLPDRFESGTPNGVGLAGLNAGVRVVLARGVESIRAHEQRLCAQLLAELQQIGRARLYGPLDPGERVAVVSFNLEGLEPSQVGLRLDEEFNILCRVGLHCSPAAHRSLGSLPRGTVRFGIGFFTSAEDVDAALRAVERIAND</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XF03</accession>
    <name>A0A0P6XF03_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_05920</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78769.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062045.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05920"/>
    <dbReference type="EnsemblBacteria" id="KPL78769">
        <property type="protein sequence ID" value="KPL78769"/>
        <property type="gene ID" value="ADN00_05920"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1660"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004703">
        <property type="entry name" value="PTS_sugar-sp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03611">
        <property type="entry name" value="EIIC-GAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="42"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="149"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="227"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="257"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="318"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="345"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="372"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="401"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL78769.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="426" mass="44914" checksum="073DC0C01076A7B5" modified="2016-01-20" version="1">MNVGLIFSIVPRLLPTFMLGLVALLGLLMMRKTFSEVITGTIKTMAGVIILFSAVDLLSGVISPISTMFSKVYAFQGEAVAVDWTAFLSQYGVPVILVMVFGFLVNLVLARVTKLKYVFLTGHIMFWNAFMVVAALADAGKITGVPLVVIGSLIHGALSTILPALIAPFVFKLTGNKDFTIGHTTTSIALVGAWIGKLVGDPSKSTEDMKISDSLSFLKSMTISTSIIMFLLYLVMGFIAGPAWAAETFSGGSQPIWYLWIIYQGILFGASLTILLTGVRLMLGEIVPAFHGFAKKVVPDAIPALDCPMVFPYGQNALAIGFPIAMIASLVTLVVFGAFGYPYVLLPLVVAAFFDVGPAAVLANATGGRRGAIVASIVGGVLLIVLQALSLPFVANTAAGFINAFGGNDFSLIAIVVGGIARLLGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XG03</accession>
    <name>A0A0P6XG03_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_14420</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000034">
        <property type="protein sequence ID" value="KPL73756.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063728.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000034.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL73756">
        <property type="protein sequence ID" value="KPL73756"/>
        <property type="gene ID" value="ADN00_14420"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL73756.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="330" mass="38140" checksum="3DAC2747F2170190" modified="2016-01-20" version="1">MRLEVWSADERALGFYRAEYSHHLQQGEQPYQVVVRLRINLPEQTARLIFHTHKLLARWRYSIEFGTDEINIEARGNYFSIPMIHHMLVHPALRFLASTRGVLMLHAGGVSRDGKSVLFSGKGGTGKTTTTAILLSDRQTGWQVHADDYVFLTPQPKSLAYMTRQHIYLPLLKWAPQVGAVMNTWERSGLFVFGHLRRWSHEGLKWPVRIEPERAWPKNDLCFEASPAGLVLLRRDQREKAELRPLADRAAALDELLEMNFEEGRHFIDLASAVHPDFDQRLAAWRHRERELLAAVIEKVPLYELVLPYTTQDFRSAQMRISALLLSIME</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGR8</accession>
    <name>A0A0P6XGR8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_03285</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061535.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03285"/>
    <dbReference type="EnsemblBacteria" id="KPL78937">
        <property type="protein sequence ID" value="KPL78937"/>
        <property type="gene ID" value="ADN00_03285"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="5"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="3">
        <location>
            <begin position="153"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL78937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="296" mass="33640" checksum="165E40AF7C771E13" modified="2016-01-20" version="1">MSKARLLVVEDDLDISNMLRIYFSSQGYDVDLAPRGTDALEKTRQGMPHLIVLDIMLPDIDGYEVCRNLRMNARTSHIPVIFLTQKDERSDKLAGLELGADDYVTKPFDIEELKLRVQNAIARSERESLTDPNTGLPAGRLIEDQLRQSMRKQGWAYMDIRLQHFDAFKDAYGFIAGNDVLRFTAMLLGEELDKDGLRDDFLGNAGGDNFVLITAQARADALKARICQRFNEEVLTHYNFIDRQQGFVQLSKTDGEMVKAPLMKLWVGIVSPETHVFSDIREITELAAEERRKQAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGS8</accession>
    <name>A0A0P6XGS8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Recombination protein RecR</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">recR</name>
        <name evidence="9" type="ORF">ADN00_03350</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">May play a role in DNA repair. It seems to be involved in an RecBC-independent recombinational process of DNA repair. It may act with RecF and RecO.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the RecR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061548.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03350"/>
    <dbReference type="EnsemblBacteria" id="KPL78947">
        <property type="protein sequence ID" value="KPL78947"/>
        <property type="gene ID" value="ADN00_03350"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.19"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01025">
        <property type="entry name" value="TOPRIM_recR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00017">
        <property type="entry name" value="RecR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000093">
        <property type="entry name" value="DNA_Rcmb_RecR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023627">
        <property type="entry name" value="Rcmb_RecR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023628">
        <property type="entry name" value="Rcmb_RecR_C4-type_Zn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015967">
        <property type="entry name" value="Rcmb_RecR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034137">
        <property type="entry name" value="TOPRIM_RecR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30446">
        <property type="entry name" value="PTHR30446"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02132">
        <property type="entry name" value="RecR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13662">
        <property type="entry name" value="Toprim_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111304">
        <property type="entry name" value="SSF111304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00615">
        <property type="entry name" value="recR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01300">
        <property type="entry name" value="RECR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5 7" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6 7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="1 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Toprim" evidence="8">
        <location>
            <begin position="83"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL78947.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="202" mass="22079" checksum="D46B2A88C9117F75" modified="2016-01-20" version="1">MPILPEPVQNLINALERLPGVGPKTASRLTFHLLRSNDDLPNQLADALKAIRTATGTCQTCFNITVAGQTECDICQDEHRDPSSICVVEEPLDVLALERTGGFTGRYHVLHGVLSPIEGIGPEDLKIRPLIERTRQGTIREIIIATNPSMEGDATALYLHQQLIPLGVRVTRLARGLPMGGDLEYADQNTLLRALAGRQEMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGW3</accession>
    <name>A0A0P6XGW3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH gntR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_03670</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061611.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03670"/>
    <dbReference type="EnsemblBacteria" id="KPL79001">
        <property type="protein sequence ID" value="KPL79001"/>
        <property type="gene ID" value="ADN00_03670"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028978">
        <property type="entry name" value="Chorismate_lyase_/UTRA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011663">
        <property type="entry name" value="UTRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07702">
        <property type="entry name" value="UTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00866">
        <property type="entry name" value="UTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64288">
        <property type="entry name" value="SSF64288"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="1">
        <location>
            <begin position="7"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="245" mass="27261" checksum="1B2A60C09C12E769" modified="2016-01-20" version="1">MAKDEPTTTSPQTYQRLQNQLAQIIAVTKPGERLLAEPELAKQMGVSRATLREAMRTFEGQGLIRRRQGVGTFVVGHPQVIETGLEVLQSIETLAKRIGLEVSMGDLKISKIEASAEQARSLQVEVEAPLLQVSRVILTDDRPVAYLVDILPQNLLSQEELQDGFNGSVLDFLLRRKQPALTKSLTDIQAVAASSSIARALEIQRGDVLLMFVARLFAEDGRVIDFSTSYFLPGYFHFQLVRRVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XH94</accession>
    <name>A0A0P6XH94_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Chaperone protein ClpB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">clpB</name>
        <name evidence="13" type="ORF">ADN00_04775</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Part of a stress-induced multi-chaperone system, it is involved in the recovery of the cell from heat-induced damage, in cooperation with DnaK, DnaJ and GrpE.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homohexamer. The oligomerization is ATP-dependent.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homohexamer; The oligomerization is ATP-dependent.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the ClpA/ClpB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061813.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04775"/>
    <dbReference type="EnsemblBacteria" id="KPL79166">
        <property type="protein sequence ID" value="KPL79166"/>
        <property type="gene ID" value="ADN00_04775"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.319"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017730">
        <property type="entry name" value="Chaperonin_ClpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036628">
        <property type="entry name" value="Clp_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004176">
        <property type="entry name" value="Clp_R_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018368">
        <property type="entry name" value="ClpA/B_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028299">
        <property type="entry name" value="ClpA/B_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041546">
        <property type="entry name" value="ClpA/ClpB_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17871">
        <property type="entry name" value="AAA_lid_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02861">
        <property type="entry name" value="Clp_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81923">
        <property type="entry name" value="SSF81923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03346">
        <property type="entry name" value="chaperone_ClpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51903">
        <property type="entry name" value="CLP_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00870">
        <property type="entry name" value="CLPAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00871">
        <property type="entry name" value="CLPAB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 9" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5 10" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="Clp R" evidence="12">
        <location>
            <begin position="3"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="11">
        <location>
            <begin position="571"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="10">
        <location>
            <begin position="410"/>
            <end position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00026057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KPL79166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="863" mass="96545" checksum="7EF8232DD0D8F0EF" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XHA5</accession>
    <name>A0A0P6XHA5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FMN_bind domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_13410</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063530.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000031.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13410"/>
    <dbReference type="EnsemblBacteria" id="KPL74831">
        <property type="protein sequence ID" value="KPL74831"/>
        <property type="gene ID" value="ADN00_13410"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1169"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007329">
        <property type="entry name" value="FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04205">
        <property type="entry name" value="FMN_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00900">
        <property type="entry name" value="FMN_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="domain" description="FMN_bind" evidence="2">
        <location>
            <begin position="70"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL74831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="146" mass="15682" checksum="90CD95BBA354FCC3" modified="2016-01-20" version="1">MNAKDKKKRKGTGCLIGFFALVVLVAVGGGVGWSLISKEHREAANLSLDAVNFNQLDDGTYHGVYPGGMYRWRANECDVTVTNGKVTSIQLAASTDPGSENTDAQMLYDRVIQAQSLQVDTISGATLTSKAYLKAVENALLQAQQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XI78</accession>
    <name>A0A0P6XI78_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8 9">Chorismate synthase</fullName>
            <shortName evidence="8">CS</shortName>
            <ecNumber evidence="4 8 9">4.2.3.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">5-enolpyruvylshikimate-3-phosphate phospholyase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">aroC</name>
        <name evidence="10" type="ORF">ADN00_02475</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8 9">
            <text>5-O-(1-carboxyvinyl)-3-phosphoshikimate = chorismate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21020"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57701"/>
            <dbReference type="EC" id="4.2.3.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8 9">
            <name>FMNH2</name>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
        </cofactor>
        <text evidence="8 9">Reduced FMN (FMNH(2)).</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8 9">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 7/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8 9">Belongs to the chorismate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.5" evidence="4 8 9"/>
    <dbReference type="EMBL" id="LGCL01000011">
        <property type="protein sequence ID" value="KPL79568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061377.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000011.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02475"/>
    <dbReference type="EnsemblBacteria" id="KPL79568">
        <property type="protein sequence ID" value="KPL79568"/>
        <property type="gene ID" value="ADN00_02475"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2805"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004107">
        <property type="term" value="F:chorismate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07304">
        <property type="entry name" value="Chorismate_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00300">
        <property type="entry name" value="Chorismate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000453">
        <property type="entry name" value="Chorismate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035904">
        <property type="entry name" value="Chorismate_synth_AroC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020541">
        <property type="entry name" value="Chorismate_synthase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21085">
        <property type="entry name" value="PTHR21085"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01264">
        <property type="entry name" value="Chorismate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001456">
        <property type="entry name" value="Chorismate_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103263">
        <property type="entry name" value="SSF103263"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00033">
        <property type="entry name" value="aroC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00787">
        <property type="entry name" value="CHORISMATE_SYNTHASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00788">
        <property type="entry name" value="CHORISMATE_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 8 9" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0274">FAD</keyword>
    <keyword evidence="8" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0288">FMN</keyword>
    <keyword evidence="7 8 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-0521">NADP</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="8">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="124"/>
            <end position="126"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="244"/>
            <end position="245"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="289"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="304"/>
            <end position="308"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="330"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL79568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="369" mass="39251" checksum="B42942DA5B8DF00F" modified="2016-01-20" version="1">MLRFLTAGESHGPQLTAIIDGLPAGLKLDIEQINLQLARRQRGYGRGHRMNIEKDRAQITAGLVYGQTTGAPLAIQIENRDWKNWQEKWQDGALSQLTTPRPGHADYPGMRKYGLDDARPILERASARETAARVAVGAVARQLAAAFGVQIGSWVEQIGPVRAQIPNLPVPQLWALAEASDTACPDETAAQAMREQIDAARRTKDTLGGVVVVTALGLPVGLGSHAQWDRRLDARVAAAMLSIQAIKGVEIGPAFENAALPGTQVHDTFLPAESGEVLRGSNRAGGLEGGMTNGQPLVVRAAMKPIATTGAKMASVNLADGQPAYAEYQRSDICAVPAAAVVTEAMLGWVLAEALVEKLGGDSLAEMRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XJA5</accession>
    <name>A0A0P6XJA5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_01925</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000007">
        <property type="protein sequence ID" value="KPL80053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80053">
        <property type="protein sequence ID" value="KPL80053"/>
        <property type="gene ID" value="ADN00_01925"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2311"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="15"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="198"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL80053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="375" mass="40760" checksum="EC28B11B34E61EDD" modified="2016-01-20" version="1">MRILVLTHEYPPVGGGGGRVAQDVCAGLAARGHEVRVLTAHCADLPFYEKRDGVEVLFLKSGRAQLFRASLKAMAGYVWQAFWQGLKQIRAWKPDVIHAQFAVPAGAAAWALSLVTGTPYVLTAHLGDVPGGTPEKTGKWFQMIYPFTPPIWKRAARVTAVSAFTRDLALKHYPVAVQVIPNGVDLQAVSAGEITLHQPPVVVFAGRFMQQKNVVQIARVMNRLADLDWRCLMLGDGPLKAEVEAEIARGGCAERFELPGWVTPQQVLEAFEQADILLMPSYSEGLPVVGVQAMAKGLALALSGAGGNPELVEAGRNGVLLEPEDEAGYEAALRVWLSDPEKLLAARRASRELAQRFDLGKIVDEYEQVLRAAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKI1</accession>
    <name>A0A0P6XKI1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_11300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063120.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11300"/>
    <dbReference type="EnsemblBacteria" id="KPL76541">
        <property type="protein sequence ID" value="KPL76541"/>
        <property type="gene ID" value="ADN00_11300"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006379">
        <property type="entry name" value="HAD-SF_hydro_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01484">
        <property type="entry name" value="HAD-SF-IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="270" mass="30018" checksum="00AF030928681A91" modified="2016-01-20" version="1">MEDVPVISFDLDGTLIDSEERIHPKDIAWLKNPPEGCLFLPTTGRPLFSARPIFENNGLVNGQALPWPLVMNNGAAIYQAGENLLEYSPFPVDVQNWLIDYAQQHPRLTFLFMDLKGSYTLWMTDYAEKLSAKHAMNLHVFVDDPRTHTFSKALILAKNCEEEVPPFLEAVRDFPLNVECSMPGFYEVLPVHVSKGAGLVRLLEKLGRAGAPVYSAGDGENDLSTFGVATFRLAPQNALEVIRQQADLVVDRTVEGVLTPLLRQAGVLDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKQ6</accession>
    <name>A0A0P6XKQ6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein-methionine-sulfoxide reductase catalytic subunit MsrP</fullName>
            <ecNumber evidence="5">1.8.5.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">msrP</name>
        <name evidence="7" type="ORF">ADN00_15130</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R-) and (S-) diastereoisomers of methionine sulfoxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a quinone + H2O + L-methionyl-[protein] = a quinol + L-methionyl-(R)-S-oxide-[protein]</text>
            <dbReference type="Rhea" id="RHEA:51296"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12314"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:45764"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a quinone + H2O + L-methionyl-[protein] = a quinol + L-methionyl-(S)-S-oxide-[protein]</text>
            <dbReference type="Rhea" id="RHEA:51292"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12315"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:44120"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </cofactor>
        <text evidence="5">Binds 1 Mo-molybdopterin (Mo-MPT) cofactor per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).</text>
    </comment>
    <comment type="PTM">
        <text evidence="5">Predicted to be exported by the Tat system. The position of the signal peptide cleavage has not been experimentally proven.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the MsrP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.5.-" evidence="5"/>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063875.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15130"/>
    <dbReference type="EnsemblBacteria" id="KPL72166">
        <property type="protein sequence ID" value="KPL72166"/>
        <property type="gene ID" value="ADN00_15130"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.728"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016672">
        <property type="term" value="F:oxidoreductase activity, acting on a sulfur group of donors, quinone or similar compound as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030091">
        <property type="term" value="P:protein repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01206">
        <property type="entry name" value="MsrP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022867">
        <property type="entry name" value="MsrP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000572">
        <property type="entry name" value="OxRdtase_Mopterin-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036374">
        <property type="entry name" value="OxRdtase_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019546">
        <property type="entry name" value="TAT_signal_bac_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007275">
        <property type="entry name" value="YTH_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00174">
        <property type="entry name" value="Oxidored_molyb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10518">
        <property type="entry name" value="TAT_signal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56524">
        <property type="entry name" value="SSF56524"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01409">
        <property type="entry name" value="TAT_signal_seq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50882">
        <property type="entry name" value="YTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 5" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="4 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0732">Signal</keyword>
    <feature type="domain" description="YTH" evidence="6">
        <location>
            <begin position="231"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Molybdopterin binding" evidence="5">
        <location>
            <begin position="82"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Molybdopterin binding" evidence="5">
        <location>
            <begin position="235"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
        <ligandPart>
            <name>Mo</name>
            <dbReference type="ChEBI" id="CHEBI:28685"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>Mo-molybdopterin</name>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL72166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="315" mass="35593" checksum="E42BBFB0B9E75BC6" modified="2016-01-20" version="1">MKKINPSEITPEHLYLSRRQFIKSAALVAGAGLLAACGMKPGSSPSATALPTSEGVSASASTDELGYPLTSFDAITNYNNFYEFSMDKSSVAPLSKDFVTAPWTIQVGGLVNKPKTYDVDDLLRLGEEERIYRMRCVEAWSMVIPWLGFPLHKLLKEVEPTSDARYVRFETLYDPKQMPGQNSLYFEWPYIEGLRLDEAMHDLTILSTGLYGKRLYPQNGAPIRLVVPWKYGFKSIKSIVKIDLVKEMPTSLWMAAAPNEYGFYANVNPNVDHPRWSQASERVIGESGRRETLLFNGYAEEVAQLYNDMDLSRWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKU5</accession>
    <name>A0A0P6XKU5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_15590</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063955.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15590"/>
    <dbReference type="EnsemblBacteria" id="KPL72239">
        <property type="protein sequence ID" value="KPL72239"/>
        <property type="gene ID" value="ADN00_15590"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="218" mass="24774" checksum="7BDA3E1E33B90528" modified="2016-01-20" version="1">MNSTSKEIIKLLKKVTATGHSQSQIFDDWLEITHLSLEALPKIAQAYSKGETYTDPPEVAEVFKRVQFRYGTSFELLKQAFAILIQSCSRSQVFFGNENGIPGDTSPDTLGEVYMEFGLPSKYTGQFFTPWPIAQFMALASMKDVENEVHERIKEACNKDVFAQALLAASMVIRDGKEAGQFFFGTLLPYIARRTKEQVEPDQKLRSHYMRLIWAIRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKW9</accession>
    <name>A0A0P6XKW9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_15795</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063995.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72276">
        <property type="protein sequence ID" value="KPL72276"/>
        <property type="gene ID" value="ADN00_15795"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="90" mass="10411" checksum="FB7F9D28129EB0BA" modified="2016-01-20" version="1">MKFTRYDNWNQIIATDFLGTFEATYNEIVIAFGDPIVKNGCTVWQFEFENGNVGFIVLGVRPGNGVIEWDIYGFEAETVDLIQEVFEQYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-04-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XL44</accession>
    <name>A0A0P6XL44_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DsbD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_00050</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL80985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060914.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80985">
        <property type="protein sequence ID" value="KPL80985"/>
        <property type="gene ID" value="ADN00_00050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003834">
        <property type="entry name" value="Cyt_c_assmbl_TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02683">
        <property type="entry name" value="DsbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="165"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="207"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="DsbD" evidence="2">
        <location>
            <begin position="8"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL80985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="238" mass="25869" checksum="322892F35E131E3A" modified="2016-01-20" version="1">MEVTLGIAFLAGLGSFFSPCVFSLMPAYLGYLGASPGVSADSPESTSRFRVFLNGVLFVLGFTALFVLVSIPISAAGQWMYDFQTWLAKIGGIVVILFGLHLSGLLHIDWLEYDLRLRVSTKNANPLVRSFLMGVFFSAGWAPCVGPVLGFILTLALAEGSISQGIFLLLFYSAGMAVPFLLMAAGFDALLSFFKSRRHWMVTVQRLSGYLMIVVGVLLFFGLFEKLAGFGNLLGINY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XLG2</accession>
    <name>A0A0P6XLG2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_01010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061088.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01010"/>
    <dbReference type="EnsemblBacteria" id="KPL81132">
        <property type="protein sequence ID" value="KPL81132"/>
        <property type="gene ID" value="ADN00_01010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016774">
        <property type="term" value="F:phosphotransferase activity, carboxyl group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000890">
        <property type="entry name" value="Aliphatic_acid_kin_short-chain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21060">
        <property type="entry name" value="PTHR21060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00871">
        <property type="entry name" value="Acetate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL81132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="330" mass="36292" checksum="A657EE6CC07965B0" modified="2016-01-20" version="1">MLIINIHPTETAWSFVDDTASTCSIHHYSKPIPMETIRQESRILYLISPGQNDLQLAPEEQRTVSQQAPHIQTIFRDCLRANPRADHRLLSENRFYQNLPPLSTRYALPADLATRFQRAGRDALTHQWAWIKAKSILPEVKSLISIHLNSAPNAVAIKNGQPVDLSAGFSQMDGLPGFHSCGEIDPSLCLTLSEKGEPPAAIEHLLAAQSGLSSVSPELASFSQIFEQPESLASKVLSHQLKKTIGGMASALNALEAIVFSGEITPALTAWLVDLLEPLTAFGFIPTSTISCESITRLNSPASRIQVFLMEDTPWKIAYEMFSQAQPLQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XLV6</accession>
    <name>A0A0P6XLV6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5 7">50S ribosomal protein L16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplP</name>
        <name evidence="9" type="ORF">ADN00_12565</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 7">Binds 23S rRNA and is also seen to make contacts with the A and possibly P site tRNAs.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 7">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uL16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063363.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12565"/>
    <dbReference type="EnsemblBacteria" id="KPL76160">
        <property type="protein sequence ID" value="KPL76160"/>
        <property type="gene ID" value="ADN00_12565"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3994"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01433">
        <property type="entry name" value="Ribosomal_L16_L10e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01342">
        <property type="entry name" value="Ribosomal_L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016180">
        <property type="entry name" value="Ribosomal_L10e/L16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036920">
        <property type="entry name" value="Ribosomal_L10e/L16_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000114">
        <property type="entry name" value="Ribosomal_L16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020798">
        <property type="entry name" value="Ribosomal_L16_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12220">
        <property type="entry name" value="PTHR12220"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00252">
        <property type="entry name" value="Ribosomal_L16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00060">
        <property type="entry name" value="RIBOSOMALL16"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54686">
        <property type="entry name" value="SSF54686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01164">
        <property type="entry name" value="rplP_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00586">
        <property type="entry name" value="RIBOSOMAL_L16_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00701">
        <property type="entry name" value="RIBOSOMAL_L16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L16" evidence="8">
        <location>
            <begin position="4"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL76160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="142" mass="16172" checksum="A21BC6F62CFF9CA1" modified="2016-01-20" version="1">MLMPKRVKFRKMMRGRMRGKALRGAEVSFGDYGLQALEPGWVSARQIEAARRAMVRVMRRRGKLWVRIFPDKPYTHRAAETRMGKGKGNVEYWVAVVKPGRIMFEIAGLPSDVAQEALHQASYKFSIKTKVVGRHEIGGEQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XLX5</accession>
    <name>A0A0P6XLX5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_01205</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000003">
        <property type="protein sequence ID" value="KPL80836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061137.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000003.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80836">
        <property type="protein sequence ID" value="KPL80836"/>
        <property type="gene ID" value="ADN00_01205"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="34"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="70"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL80836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="154" mass="16801" checksum="A4057CF3E77C3E5E" modified="2016-01-20" version="1">MEETKEIVPAQQTAPPQPENPEAELPAESNRGKVILVVLGIVLLVGLTVAGIVTLFDVGAEKTSHIRDVFIIFMALESLIIGAALVILIVQLSILINLLQNEIKPIIDSTSETVNTIRGTASFISDNLSEPVIKLNEYVAYISKFVEILRPKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XMN7</accession>
    <name>A0A0P6XMN7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_08720</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000022">
        <property type="protein sequence ID" value="KPL77665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062609.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000022.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08720"/>
    <dbReference type="EnsemblBacteria" id="KPL77665">
        <property type="protein sequence ID" value="KPL77665"/>
        <property type="gene ID" value="ADN00_08720"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="172" mass="19756" checksum="02505106271B7A2F" modified="2016-01-20" version="1">MNYNFVPMNRAYASTIVDTWKYEQEYSIYDYANEADHMLDEEGWGRGIFAVLNPQGDLVGELSVEFFDAQGQPADFCNFDDQALISERELWIGFGLRPDLVGQGFGVDFVTACVEYAARRFGYRGEYIRLGVAMFNQRAIKTYEKAGFQKFDQTVGEISGKTFECAYMRKRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-08-12" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XMT4</accession>
    <name>A0A0P6XMT4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_11260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063112.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76535">
        <property type="protein sequence ID" value="KPL76535"/>
        <property type="gene ID" value="ADN00_11260"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="22"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="259" mass="27478" checksum="D3156621F3BD91C6" modified="2016-01-20" version="1">MPLSNGIYYACSHSGPTGLPPLIFIHGAGSDHLCWPAQLRRLRGWTVLAVDLPGHGRSEGAAVQSVEGYAASLLAFLDGLQLYQVVLVGHSMGGAVAQHLARCCPERVAGLALLSCGSNLKGANDLAELLCNPVTRAGGLHKLEDLLFARGAEAALVNRTMQSLRAARPGVIFADWLACAHFESSGWLGQISVPTWVAVGAQDRLTPLGASIYLTNQIPHAQLRVVERAGHMLMLEQPQKTAEGLIAWLEGLNLGLAQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XN12</accession>
    <name>A0A0P6XN12_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_08060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062476.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77830">
        <property type="protein sequence ID" value="KPL77830"/>
        <property type="gene ID" value="ADN00_08060"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.612"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL77830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="451" mass="50680" checksum="C2234FC36F7AF90F" modified="2016-01-20" version="1">MSEQIHPTSSSRIGFHYFQDQNHYREFDLCEWLPRLQSLNASWLVLQATLNRAVPETFLRGLLSSGIQPVIFSPMDLQKPPALEEIKPLFTAYAHWGARYIILADQPNNRAAWNTSAWVQEDLVERFLDRYLPAANLALQEGLQPVLPPLTPGGSYWDTAFLRSLLESLQRRRQVEQLDHLVLTAYAWTHDRHLNWGAGGPERWPAAKPYQSTPNEEDQLGYHNFDWVQTIARAVTGKETPTLLLQAGAKGVTSSSAAAVETSLVQQELLKNLLGLPAVDPADTDIKLDPLPESIIACNFWLLADEPGGEFASDTWFSTQGEPLPAAHLCQNITTAAPTPADETPAWMQQEFFVKEEKTVQRRPIQHYLLLPVQEWGIAEWHLEVIKPFVRKHKATIGFSLKEAVLACKVTVIGNEDVFPEKVLNQLRSTGCQVERIQGDGTTIATILAER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XNX5</accession>
    <name>A0A0P6XNX5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_07500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07500"/>
    <dbReference type="EnsemblBacteria" id="KPL78296">
        <property type="protein sequence ID" value="KPL78296"/>
        <property type="gene ID" value="ADN00_07500"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3326"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010905">
        <property type="entry name" value="Glyco_hydro_88"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07470">
        <property type="entry name" value="Glyco_hydro_88"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="102"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="157"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="217"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR610905-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR610905-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="377" mass="42584" checksum="F9399A92675E4F19" modified="2016-01-20" version="1">MLREVGLDNPNELLRERLEAVIPFAEKQVERMVSQHPDCFPVFTTQGVWSCTQEARDTWCEGFFGGMMWLLYSVTGKAVWKERAEHYSRLIASRRADESMHDLGYLFLFTALRAYELTGSEEWQAVTLEAAETLAKHYQPQGHYLCSAFGPESLLIDQMVDVGLLFYAAQVKRDRGLFRMARNHTSTSRRMLLRGDGSTAQEGLFDRITGEYIKPGTRQGWRADSCWARGQAWALYGFAKVYEYTRDAHDLASAELLAQYYLENAPAHGVPPNDFDEPGPRFGFETSAAAVAACGLWKLARLTGDASRAVLYLQSALQILDTLTSTTFLASESEEWEGLIKHGIYHVRLGLGVDESLIFGDHFFLEAVCEALKDETW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XP01</accession>
    <name>A0A0P6XP01_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">LuxR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_07740</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062405.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07740"/>
    <dbReference type="EnsemblBacteria" id="KPL78333">
        <property type="protein sequence ID" value="KPL78333"/>
        <property type="gene ID" value="ADN00_07740"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3379"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="8"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="146"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL78333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="217" mass="23685" checksum="561D38B54C9A21C0" modified="2016-01-20" version="1">MNANQPIRVMLVDDHNVVRSGLGAFLMVFDDLELVGEASNGREAVRLAERLQPDVILMDLVMPEMDGAAATKAIREKWQNIQIVALTSFKEDELVQGALQAGAIGYLLKNVGADELADAIRSAHAGRPTLAPEAAQALIHASRMPADRPGFDLTDREREVLELLVEGYSNPEIADKLVVSRSTIKFHVSSILSKLHVTSRTEAVAVALKEKLVKKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XPR3</accession>
    <name>A0A0P6XPR3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_05235</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05235"/>
    <dbReference type="EnsemblBacteria" id="KPL78662">
        <property type="protein sequence ID" value="KPL78662"/>
        <property type="gene ID" value="ADN00_05235"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010181">
        <property type="entry name" value="CGCAxxGCC_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013118">
        <property type="entry name" value="Mannitol_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013131">
        <property type="entry name" value="Mannitol_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09719">
        <property type="entry name" value="C_GCAxxG_C_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01232">
        <property type="entry name" value="Mannitol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08125">
        <property type="entry name" value="Mannitol_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mannitol_dh" evidence="1">
        <location>
            <begin position="5"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="domain" description="Mannitol_dh_C" evidence="2">
        <location>
            <begin position="154"/>
            <end position="376"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="570" mass="63511" checksum="1329C3104F561D80" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQ16</accession>
    <name>A0A0P6XQ16_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_06305</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062114.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06305"/>
    <dbReference type="EnsemblBacteria" id="KPL78827">
        <property type="protein sequence ID" value="KPL78827"/>
        <property type="gene ID" value="ADN00_06305"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1763"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="345" mass="39098" checksum="73027A6D77DE31FD" modified="2016-01-20" version="1">MKIYITGISGFLSINLVRYLLAQGYEDISGIDLVDFTYPERDQITFLQGDIRDREAVKRSMQGADIVIHTAAALPLYTPEEIYSTDVEGTRILFEQALEYGVKRFIHISSTAVYGVPDHHPLYETDKMIGVGPYGEAKVKAEEICHEFRDKGMCVPVLRPKSFVGPERLGVFAIFYEWASEGRHFPMIGSGNNRYQLLDVEDLCRAIHACITLDADAVNDTFNIGAARYTTMKQDYQAVLDAAGFGKRIIPFPVGPVILALKVLEAMKLSPLYPWIYETASKDSFVSIEKAQKVLGFDPQYSNQEAMLRNYQWYLENKDGFTEGEGVTHRVPWKQQALKLFKVFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XRA4</accession>
    <name>A0A0P6XRA4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_15140</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063877.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72167">
        <property type="protein sequence ID" value="KPL72167"/>
        <property type="gene ID" value="ADN00_15140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133187" evidence="2">
        <location>
            <begin position="27"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL72167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="283" mass="30218" checksum="55862ACE3495E23E" modified="2016-01-20" version="1">MRKTFGLSITLCVFLLAGCNLPTRQAAPDADQIATSVALTLTAQPVELLIATPTIPTIQMATSQPTEPTATIAPQASATPTLTATLPAGDPRQDRGTPTWQRNMDDGKSFGLEEAYDDGNTRFEVSNGVMSVSSNSSNGFRGWRLSNPKPQNMYLEGIFRTNTCSGGDTYGLVFRAADYTSGYGYYAGFTCDGKYMLSRWTSSGTSTIISATQSDLILSGSNQTNRLGILADGKNISLYANGKLLETVTDSGISDGGHIGPFISAFSGGFSYALDEIVYWDLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XRE2</accession>
    <name>A0A0P6XRE2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_08080</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062480.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08080"/>
    <dbReference type="EnsemblBacteria" id="KPL77833">
        <property type="protein sequence ID" value="KPL77833"/>
        <property type="gene ID" value="ADN00_08080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL77833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="286" mass="32790" checksum="FC60058838D595C9" modified="2016-01-20" version="1">MPVISLRQLQAHREETFRLRPEARLHSAQDALEFVNQRGFVFFWPNQGTILPSIWNATVGDRPVPDNHDDPGHVTWGWKDDLLDKRVWFYGRVIRRRNAMIALNLLPSFYALSPNYGDPEHDYLDQYQQGVMTFEAKSIYEALLHEGPLDTLSLRRAARLSSETSSARFSRSLDDLQKEFKILPVGVSRVGGWNYAFIYDIVPRYHPELQEQARYISELEAQQTLAAVYLHSVGALRARDLVHLFRWSPADAARALQRLAATDPELIACSHPTEKGEWLALPALVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XRG3</accession>
    <name>A0A0P6XRG3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_02905</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000013">
        <property type="protein sequence ID" value="KPL79393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061456.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000013.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79393">
        <property type="protein sequence ID" value="KPL79393"/>
        <property type="gene ID" value="ADN00_02905"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="209" mass="22636" checksum="0B3A97E0B58F35AF" modified="2016-01-20" version="1">MPTLEELIQCGLSPAQIGQQALQDETLLRELFGGIAPQKQKKEVRETCSQALLFLSQQHPQTLLPHWGQFSALLPSGNGFSQYVAVHALANLSAADQGECMQADLDAFLALLDSPSVMVAGHTAAAAGQIAAACPTLQATITERLLKTSTPGRDAERAALIVSYVLDAFDLYIEVSPQRERMVGLAFSQIDCASPKTRKRAKQFLDRWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XTJ4</accession>
    <name>A0A0P6XTJ4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UPF0033 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_06810</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfur carrier protein TusA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000018">
        <property type="protein sequence ID" value="KPL78428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062228.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000018.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06810"/>
    <dbReference type="EnsemblBacteria" id="KPL78428">
        <property type="protein sequence ID" value="KPL78428"/>
        <property type="gene ID" value="ADN00_06810"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001455">
        <property type="entry name" value="TusA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036868">
        <property type="entry name" value="TusA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01206">
        <property type="entry name" value="TusA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64307">
        <property type="entry name" value="SSF64307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UPF0033" evidence="2">
        <location>
            <begin position="4"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="69" mass="7723" checksum="77BCD3CF46A0F810" modified="2016-01-20" version="1">MATKVDARGLSCPQPIMLAQQAMRAGDFPIEVWVDSVTSRENVRRIAERKGYNVTIQEQDGEFVLAISK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XV42</accession>
    <name>A0A0P6XV42_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_04375</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061735.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04375"/>
    <dbReference type="EnsemblBacteria" id="KPL79104">
        <property type="protein sequence ID" value="KPL79104"/>
        <property type="gene ID" value="ADN00_04375"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03225">
        <property type="entry name" value="ABC_cobalt_CbiO_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015856">
        <property type="entry name" value="ABC_transpr_CbiO/EcfA_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="5"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="39"/>
            <end position="46"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL79104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="289" mass="32042" checksum="2947D4A724EB1599" modified="2016-01-20" version="1">MTSLIDIKNYTWRYLYTNQPAVKNINLTLDEGLFLGVIGPNGSGKTTLAYSLNGLIPGQYHGIKEGEVLIDGTEVEAYAKGTLQRQVGVVFSDPEAQFTAMTVEDELVFGMENLGMSIPEIRERLEWVVSLTDLQPLLLKPPYEISGGQKQRVALAAVLAMTPRVMILDEPTSMLDPISRKRVFDVLAKLKKEQKNTIIVIEHSLENLIPLADRMAFMLNGELVLEDETRAFFAQIAMLMEKGIFPPDAMQFFHQLALQHMYSGALPLTVEEATQSLRASLARAAGGQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XVE7</accession>
    <name>A0A0P6XVE7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Glutamyl-tRNA(Gln) amidotransferase subunit A</fullName>
            <shortName evidence="7">Glu-ADT subunit A</shortName>
            <ecNumber evidence="7">6.3.5.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">gatA</name>
        <name evidence="9" type="ORF">ADN00_01750</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Allows the formation of correctly charged Gln-tRNA(Gln) through the transamidation of misacylated Glu-tRNA(Gln) in organisms which lack glutaminyl-tRNA synthetase. The reaction takes place in the presence of glutamine and ATP through an activated gamma-phospho-Glu-tRNA(Gln).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln) = ADP + H(+) + L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17521"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="Rhea" id="RHEA-COMP:9684"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.5.7"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Heterotrimer of A, B and C subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the amidase family. GatA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.7" evidence="7"/>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061238.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01750"/>
    <dbReference type="EnsemblBacteria" id="KPL80591">
        <property type="protein sequence ID" value="KPL80591"/>
        <property type="gene ID" value="ADN00_01750"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1112"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030956">
        <property type="term" value="C:glutamyl-tRNA(Gln) amidotransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050567">
        <property type="term" value="F:glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00120">
        <property type="entry name" value="GatA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000120">
        <property type="entry name" value="Amidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020556">
        <property type="entry name" value="Amidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004412">
        <property type="entry name" value="GatA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11895">
        <property type="entry name" value="PTHR11895"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="SSF75304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00132">
        <property type="entry name" value="gatA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00571">
        <property type="entry name" value="AMIDASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Amidase" evidence="8">
        <location>
            <begin position="25"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="85"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="7">
        <location>
            <position position="160"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="7">
        <location>
            <position position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL80591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="497" mass="53676" checksum="70BA53EBB9E66DE4" modified="2016-01-20" version="1">MKAENVMSVRATLDALRQGDITSYDLTKACLQRLEALNGCLHAFLTPTPELALRQADEADRKYAAWRQDPSIELPPLLGLPMAIKDVLAQSGVRCTCGSKILENFIPPYTATSVERLLRAGVVTVGKTNTDEFAMGSSTENSAYGPTHNPWNLECVPGGSSGGSAAAVAARIVPAALGTDTGGSVRQPAAFCGVTGLKTTYGRVSRYGLVAYGSSLDTVGVLAQSAEDAALILPHIAGRDPRDATSMDLPVPSVRLDQASVQGLRVGVPKEYFIDGIQPEVEQGVRAAIEAYRQMGAQIVEISLPNTAYALPVYYLIAPAEASANLARYDGIRFGPREEGERMWEMFFNTRGKRFGAEVKRRIMLGTYALSAGYYDAYYGQAQKVRTLIKHDFESAFNEVDVIAAPVAPTTAFRIGQHSGSPLEMYLEDIFTLPANLAGVPGIAFPVGFDSQGLPVSMQLMGPHFREDALLRAAHAYQQATDWHLQIPEGLDRKDNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XVQ8</accession>
    <name>A0A0P6XVQ8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PRK domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_02945</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000013">
        <property type="protein sequence ID" value="KPL79397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061461.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000013.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02945"/>
    <dbReference type="EnsemblBacteria" id="KPL79397">
        <property type="protein sequence ID" value="KPL79397"/>
        <property type="gene ID" value="ADN00_02945"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006083">
        <property type="entry name" value="PRK/URK"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00485">
        <property type="entry name" value="PRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PRK" evidence="1">
        <location>
            <begin position="26"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="219" mass="24559" checksum="FC0D702F5130E08F" modified="2016-01-20" version="1">MRREDLLEELAQYLLRHRLDHPLRVGIDGIDTAGKTSLADELKPLVEAAGRPVLRASIDGFHNPREVRYRQGAGSPEGYFADSFDLEAARGLLLNPLGPGGRRLVRTASYNVRQEREVQAPEVKVPANCVLLFDGIFLARPELAGAFDLRVFVHIDFETCLARAELRDRAHLGDAVRQRYLQRYIPAQQAYLAGCHPRETANVVIINDDLANPSLEIRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XWH9</accession>
    <name>A0A0P6XWH9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AraR_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_07925</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062451.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07925"/>
    <dbReference type="EnsemblBacteria" id="KPL77807">
        <property type="protein sequence ID" value="KPL77807"/>
        <property type="gene ID" value="ADN00_07925"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045830">
        <property type="entry name" value="AraR_wHTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19368">
        <property type="entry name" value="AraR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AraR_C" evidence="1">
        <location>
            <begin position="152"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF19368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="230" mass="26385" checksum="87127540596ED38A" modified="2016-01-20" version="1">MDQPDKSTPTQATQHTLEIRLVIFTLKDNQLAVFLSPSSLPQANDVWEIPGVPANIEQNLEETANQYLRQNMGMDEAYLEQLYTYGDTQRHPQYPLVSVVFFALIPADASQNELRKRAALRCFPVNALPSLALDHPLIVEYALRRLRYKLEYSAVGFELLPETFTLSELQNTYEIILGVSLDKRNFRRRILEAGIIESTPHRRAGEGRPAQLYRYRPDAIAEVKARRLFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XXT8</accession>
    <name>A0A0P6XXT8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_06895</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062249.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78209">
        <property type="protein sequence ID" value="KPL78209"/>
        <property type="gene ID" value="ADN00_06895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="11"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="179"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="333" mass="37883" checksum="11E6A04D3BE6683F" modified="2016-01-20" version="1">METWKTNKDGLVFRSYTGEADLPELVSVFNASSQADKADWVTNLVEMSKEYQPGEHFDPQRDSVLVERDGRLVAFGEVRHYYQQESGSWQHRVDGLVRPDWRGHGIGSALLEQLRGVCAGLAESGQSEVGHRLHTYAWGTQTARLAFLEAAGFSPVEFMYSMTRTNLNEITITDLPEGLQTRAVLRSDARDLWNLFNEAFLDHPGFFRQNEADFLEWESSSYFDPELCVAAWEGERMVGMVINHIDAVENREMRRERGYLMRIATLREWRKRGVARALIGHSLKLLNQKGCNEAALRVNVRNPTGALHLYESLGFVVTSQLKIMEMDLKAGLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y1N8</accession>
    <name>A0A0P6Y1N8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_12655</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063385.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000027.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12655"/>
    <dbReference type="EnsemblBacteria" id="KPL75495">
        <property type="protein sequence ID" value="KPL75495"/>
        <property type="gene ID" value="ADN00_12655"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL75495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="218" mass="25208" checksum="83C40067A46E03DC" modified="2016-01-20" version="1">MKSIILSSFDSLPYFTMEAVKQLLGVESVAAGTIQTALYRWMKAGQIIQLKKGVYMTRRFFEQHRAIVDFAPMVSAILIPQSYLSLEYILQRNGILTEMTYPVTAVTLKQTRVFENTLGTFAYRNIKADLYRGFLFSEYMGIPIAQATVAKALFDFLYFRPWKSSRRLAGYDLAEDLRLNLDDFSENDQVEFESFVEISKSKKMEQILKALRKTVWQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y3N7</accession>
    <name>A0A0P6Y3N7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Chorismate mutase</fullName>
            <ecNumber evidence="2">5.4.99.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_02450</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>chorismate = prephenate</text>
            <dbReference type="Rhea" id="RHEA:13897"/>
            <dbReference type="ChEBI" id="CHEBI:29748"/>
            <dbReference type="ChEBI" id="CHEBI:29934"/>
            <dbReference type="EC" id="5.4.99.5"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.5" evidence="2"/>
    <dbReference type="EMBL" id="LGCL01000011">
        <property type="protein sequence ID" value="KPL79563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061372.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000011.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02450"/>
    <dbReference type="EnsemblBacteria" id="KPL79563">
        <property type="protein sequence ID" value="KPL79563"/>
        <property type="gene ID" value="ADN00_02450"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004106">
        <property type="term" value="F:chorismate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02185">
        <property type="entry name" value="AroH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008243">
        <property type="entry name" value="Chorismate_mutase_AroH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21164">
        <property type="entry name" value="PTHR21164"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07736">
        <property type="entry name" value="CM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005965">
        <property type="entry name" value="Chor_mut_AroH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="SSF55298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01796">
        <property type="entry name" value="CM_mono_aroH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51167">
        <property type="entry name" value="CHORISMATE_MUT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="1 2" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <position position="7"/>
        </location>
        <ligand>
            <name>prephenate</name>
            <dbReference type="ChEBI" id="CHEBI:29934"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>prephenate</name>
            <dbReference type="ChEBI" id="CHEBI:29934"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="107"/>
        </location>
        <ligand>
            <name>prephenate</name>
            <dbReference type="ChEBI" id="CHEBI:29934"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR005965-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="124" mass="13687" checksum="215E143ED9FC5285" modified="2016-01-20" version="1">MRCLGIRGAIHVESNSEAAILAAAHQLLSEIVAQNQLDPADLAAVTFTVTKDLTAAYPARAAREMGWQMVPLMCAQEMDVPGSLPACLRVLLLWNTHKTQDQVRHVYLGRARALRPDLVKEEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y492</accession>
    <name>A0A0P6Y492_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">Cell shape-determining protein MreC</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4 5">Cell shape protein MreC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_02230</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in formation and maintenance of cell shape.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the MreC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000009">
        <property type="protein sequence ID" value="KPL79800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061332.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000009.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02230"/>
    <dbReference type="EnsemblBacteria" id="KPL79800">
        <property type="protein sequence ID" value="KPL79800"/>
        <property type="gene ID" value="ADN00_02230"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2768"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042177">
        <property type="entry name" value="Cell/Rod_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042175">
        <property type="entry name" value="Cell/Rod_MreC_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007221">
        <property type="entry name" value="MreC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34138">
        <property type="entry name" value="PTHR34138"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04085">
        <property type="entry name" value="MreC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038471">
        <property type="entry name" value="MreC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00219">
        <property type="entry name" value="mreC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0133">Cell shape</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="65"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00032089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR038471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL79800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="281" mass="30598" checksum="0AE3440B200506D4" modified="2016-01-20" version="1">MKNNFSLNWQTAVVLLIAGGLIFLALSGFLSPLVNNALSPVISAQAWMASRFNALYEFLTVPRDVATLRQRNAELENQVSNLQTQVIELQQQLREAQVLYALLDFARKRPENEYVASSVIGKDPSPFLHYIIIDHGSDDGIRHGMPVVTEQGLVGRVDAVTASASRVQLITDPSSVINIRLQKAQTEALLTGSLTGDVNLSMVPQDINLQTGDLVLSSGLGANYPGDVVVGQVITVRKQETDLFQSASVQPAVDFSNLRAVLVITNFRPVNIEPLIPVETP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y5J5</accession>
    <name>A0A0P6Y5J5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutamate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_01780</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Glu/Leu/Phe/Val dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01780"/>
    <dbReference type="EnsemblBacteria" id="KPL80596">
        <property type="protein sequence ID" value="KPL80596"/>
        <property type="gene ID" value="ADN00_01780"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033524">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006097">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02812">
        <property type="entry name" value="ELFV_dehydrog_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00074">
        <property type="entry name" value="GLFV_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ELFV_dehydrog_N" evidence="3">
        <location>
            <begin position="38"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL80596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="162" mass="18353" checksum="9F140B189E2013FE" modified="2016-01-20" version="1" fragment="single">MTASVTNAFEMAQAQFDHVAELLALDPQVREFLRWPLREYHFRIPVRMDDGSIRLFEGFRVQHNDSRGPNKGGIRFHPAETADTVRALAMWMTWKCAVVDIPLGGGKGGVIVDPATLSLGEKERLVRGWVQQMWKNIGPRQDVPAPDVGTTPQMMGWMMDEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y605</accession>
    <name>A0A0P6Y605_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">VOC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10670</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062983.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10670"/>
    <dbReference type="EnsemblBacteria" id="KPL77022">
        <property type="protein sequence ID" value="KPL77022"/>
        <property type="gene ID" value="ADN00_10670"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="14"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="138" mass="14927" checksum="C89534C686D293DD" modified="2016-01-20" version="1">MPKGTHNSTLPGCGFHHISIQTVDFDAALRFYRDTLGMREHQPFEVGGRRFVLLDCGDGSFVELQEPEGGTPIPSETVPLAHFALAAADTRAAVEMVRQAGCPITMEPKQVNLGGKLQAVVAFFTGPNGESVELFQEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y6Q7</accession>
    <name>A0A0P6Y6Q7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_09015</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062667.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77269">
        <property type="protein sequence ID" value="KPL77269"/>
        <property type="gene ID" value="ADN00_09015"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4037"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="535"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="565"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="441"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="606" mass="69123" checksum="2571372A7AD3B313" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YA56</accession>
    <name>A0A0P6YA56_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AP_endonuc_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05510</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061973.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78704">
        <property type="protein sequence ID" value="KPL78704"/>
        <property type="gene ID" value="ADN00_05510"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="1">
        <location>
            <begin position="48"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="268" mass="29828" checksum="E886A62061E43A98" modified="2016-01-20" version="1">MPGKYRLGTTSYIMEAGLLENAHYLAGKVQDMELVLFDREDGQCNLPSAQVVSALKQAAQDKDLSYTVHLPEDLKWQNGIGEPHPSLAKARKAILSTQDLQPLAYVTHLDGRGVDWRSRQERKTWEDQALKALERTAEWAGGWQRIALENLEGFPLHYLDGVFARVPVSACLDIGHLWIDGWDAAAVLSNGVDWPRIRVVHLHGIAPQGSDHHSLVFQSHAELVAVFDLLARNQFSGVLTLEVFGEEDFYSSLQIVQNVLAAQKEGGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YB98</accession>
    <name>A0A0P6YB98_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_04970</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79198">
        <property type="protein sequence ID" value="KPL79198"/>
        <property type="gene ID" value="ADN00_04970"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="64" mass="7314" checksum="58C33831482EEC03" modified="2016-01-20" version="1">MTFQVLEFSFLWNFLNPSYDYRIQRMQAPAIGQAASSRGTSWADSNLASRPVRNSAKLSRMDIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YEK4</accession>
    <name>A0A0P6YEK4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GTP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01295</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061157.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01295"/>
    <dbReference type="EnsemblBacteria" id="KPL80515">
        <property type="protein sequence ID" value="KPL80515"/>
        <property type="gene ID" value="ADN00_01295"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1011"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04867">
        <property type="entry name" value="TGS_YchF_OLA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004396">
        <property type="entry name" value="ATPase_YchF/OLA1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023192">
        <property type="entry name" value="TGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013029">
        <property type="entry name" value="YchF_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06071">
        <property type="entry name" value="YchF-GTPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006641">
        <property type="entry name" value="CHP00092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="SSF81271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00092">
        <property type="entry name" value="TIGR00092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TGS" evidence="1">
        <location>
            <begin position="271"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="356" mass="39397" checksum="6E616BFD61F8C716" modified="2016-01-20" version="1">MRLGIFGLPQSGKTTLFNALTGSSTPTLPVSGKIEVHTAVVDVPDPRVDRLSGMFNPKKTIYAKVTYADIAGLDGSAGRSGISGQLLNHLTQMDGFIHVVRCFEDENVPHQAGSVNPQRDLETMDSEFILNDLIAVERKLERLTDERRKGGGRDKGLIERDIELFNRMHAALSEETPLRDIEISEEEAKTLSGFGLLSQKPVLVVFNLSEGQTAPQIAYEHQRSMVVALQGKLEMDIAQLPPEDREMFMAEYNIEEPSLNRMIRLSYDLLGLQSFFTVGPDEVRAWTVERGATAPVAAGVIHTDLQKGFIRAEVVAYDDLVELGGLTECKGKGKLRLEGKEYIVKDGDVLNIRFNI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GKL8</accession>
    <name>A0A0N8GKL8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PfkB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_18565</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064538.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18565"/>
    <dbReference type="EnsemblBacteria" id="KPL70058">
        <property type="protein sequence ID" value="KPL70058"/>
        <property type="gene ID" value="ADN00_18565"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00583">
        <property type="entry name" value="PFKB_KINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="3">
        <location>
            <begin position="11"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL70058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="317" mass="33935" checksum="069EF9DBEFA9E900" modified="2016-01-20" version="1">MTFEEPSYSDKRILVIGASTLDIVGRLNVIPEPGTSTPAKIRPTFGGVARNVAENLARLGQKVSLITVVGPSIFGEQLLQQTAAAGVDVSATIHTEEYRTSTYLAVVNPSGQLQFGLDDMRAISTLKPEHIEQNAHLFKDAGMVFVDMNLSPATLRSIFRQARLAKVPIAADATSKKLAPRLIPFLPKLHLVTANMDEASILCDGACQVTGRQSAIQAARHFISKGADYALIQMAEFGVCYANSDISGHIPAIRTSILDPTGAGDALTATLIFGLINQIPLDDAIQLGIAAASLTLRYPGAVVPELSLEKLYDHLMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GLB9</accession>
    <name>A0A0N8GLB9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_16455</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064132.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72066">
        <property type="protein sequence ID" value="KPL72066"/>
        <property type="gene ID" value="ADN00_16455"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3734"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="195"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="229"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="254"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="282"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="10"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="161"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL72066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="303" mass="32587" checksum="97314523CBCAF2F2" modified="2016-01-20" version="1">MENGLLVYGGQIAALTAAFLWAAVSFLFLRIREHISAMELNLVKGLLAILLLGGTSFLLSEPLSAIHPQGLLILLVSGVIGIGIGDTAYFQALKDLGARLALLLMSLAPPIAAIIALIFLNESLSVWAWVGIFLAVGGIIWVVTEENENGSAQANPKYRWRGIIFGLLSAIGQATGVVMSRAVLTQTEISSLQSAVLRLVAGAAFILVWLLISHQPPGKWMKKNEARKLWGWIFGAAFFGTYMCLWLQQISLDLAPAGIVQTLLSTSPLFVLPMAALRKEKISVRAIVGAMVAFAGIYLLFAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GM27</accession>
    <name>A0A0N8GM27_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">VOC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_14110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063670.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000033.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14110"/>
    <dbReference type="EnsemblBacteria" id="KPL74130">
        <property type="protein sequence ID" value="KPL74130"/>
        <property type="gene ID" value="ADN00_14110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="5"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="123" mass="13799" checksum="BC70D7F329508A64" modified="2016-01-20" version="1">MAKNPVVFWELASHDQEKTAQFFRDVFEWEINFNEQLGFYIVPERFTPEAMEGGIFTLKRARLPFIALYIQVEGIEEMAQKVEAAGGSILDPVTRLGSGSKLCLFNEPSGVTFAMIEPAPKPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMS9</accession>
    <name>A0A0N8GMS9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L36</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">rpmJ</name>
        <name evidence="6" type="ORF">ADN00_12490</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the bacterial ribosomal protein bL36 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063348.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12490"/>
    <dbReference type="EnsemblBacteria" id="KPL76146">
        <property type="protein sequence ID" value="KPL76146"/>
        <property type="gene ID" value="ADN00_12490"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00251">
        <property type="entry name" value="Ribosomal_L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000473">
        <property type="entry name" value="Ribosomal_L36"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035977">
        <property type="entry name" value="Ribosomal_L36_sp"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42888">
        <property type="entry name" value="PTHR42888"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00444">
        <property type="entry name" value="Ribosomal_L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57840">
        <property type="entry name" value="SSF57840"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01022">
        <property type="entry name" value="rpmJ_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00828">
        <property type="entry name" value="RIBOSOMAL_L36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL76146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="37" mass="4265" checksum="9940D8E3DBD6B950" modified="2016-01-20" version="1">MKVTASIKKRCAKCKIVKRHGNLFVICENPNHKQRQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GN35</accession>
    <name>A0A0N8GN35_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76994">
        <property type="protein sequence ID" value="KPL76994"/>
        <property type="gene ID" value="ADN00_10490"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2569"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="321" mass="34695" checksum="2512A0F0A5A37C84" modified="2016-01-20" version="1">MPSFWRMMILLVLAAGLALIAWLLFNPNRTNALGATELPVSLHSGLVANYSADLREYVVPAVRMELVEEALADAAAQEEQVSEVLQNLETPVPTVTPRRIDPTATPREEDDDDDQQEQKPAPPTAAPPAATATSQSQPTQAAPSSTSVPPTQVVNATPTSIKPTATQAVPTSIIIAPSATKPAPTATSQWSWPYWTPIWTPRWWPTSTPVPPTAVPSRVPTQAPTQAPTQPPAPTSPPPAPTSAPVQPTSAPVEPTPENTRRPRWWPTRSSYFAPFDVPDERMASQATLPVAVTGTQTPPNSLWSNLESFWQRVVDWLTPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GN68</accession>
    <name>A0A0N8GN68_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transport permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_08955</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ABC-2 integral membrane protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08955"/>
    <dbReference type="EnsemblBacteria" id="KPL77258">
        <property type="protein sequence ID" value="KPL77258"/>
        <property type="gene ID" value="ADN00_08955"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4024"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="31"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="68"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="139"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="228"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="7">
        <location>
            <begin position="15"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL77258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="260" mass="30465" checksum="6F6CB7B8B77C8331" modified="2016-01-20" version="1">MIPYMKELFRSRELLYTWTMRDFKVRYSQSILGAAWAIIQPFSLMVVFSIIFSNIIRVPTDGIPYPLFSYVALLPWTFFANSLTFAIPSLVNNMNLVSKIFFPREILPLSSILVCLLDFLISCSIFVLMMIWYRVPIGWTTLLVPVILIIQFVLTYGISLLASAINVFYRDVRFVIPLVLQIWMYLSPIIYPVNLVPEWLQPFYFINPMATIIESYRRVVLYQQLPDWRYLGLAAAVSIVLIIFTYPYFKRAERQFADLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNB7</accession>
    <name>A0A0N8GNB7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_08615</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000022">
        <property type="protein sequence ID" value="KPL77650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062589.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000022.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77650">
        <property type="protein sequence ID" value="KPL77650"/>
        <property type="gene ID" value="ADN00_08615"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL77650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="541" mass="61972" checksum="60F5D1734C919440" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNE6</accession>
    <name>A0A0N8GNE6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Dipeptidase</fullName>
            <ecNumber evidence="4">3.4.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_08375</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>an L-aminoacyl-L-amino acid + H2O = 2 an L-alpha-amino acid</text>
            <dbReference type="Rhea" id="RHEA:48940"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:59869"/>
            <dbReference type="ChEBI" id="CHEBI:77460"/>
            <dbReference type="EC" id="3.4.13.19"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the peptidase C69 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.-.-" evidence="4"/>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062533.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08375"/>
    <dbReference type="EnsemblBacteria" id="KPL77882">
        <property type="protein sequence ID" value="KPL77882"/>
        <property type="gene ID" value="ADN00_08375"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.677"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070004">
        <property type="term" value="F:cysteine-type exopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016805">
        <property type="term" value="F:dipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005322">
        <property type="entry name" value="Peptidase_C69"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12994">
        <property type="entry name" value="PTHR12994"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03577">
        <property type="entry name" value="Peptidase_C69"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0224">Dipeptidase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL77882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="442" mass="49072" checksum="DE701CEEC1D886C7" modified="2016-01-20" version="1">MCDTFVAVGSATKDGSVILGKNSDREPNEAQVLEIHPAADHPTGSHVKCTYVQIPQVAHTHAVLLAKPFWIWGAEMGANEHGLAIGNEAVFTKMPLEKNGGLIGMDFLRLALERSKTAYEGLQCIISLLKQYGQGGNCGFTHPFYYHNSFILADAENAWVLETAGSQWAAKKVEGVRSISNRLSLGNDWDLASEDLVETALERGWCKSRRDFHFARCYSDVLYTRLSDSQKRQQSAQCQLEQMNGRLTVESAMRILRSHAVEAEKFSPDSGLLGADVCMHAGFGPVRGSQTVGSMVSHLKEPFTHWLTGTSAPCLSLFKPVWVDSGLPNGYVPPTGIYNEESLFWKHEKLHRKVIFRYRDRAARIHSDIDRIQASWLAAADGHEKADRAQRGAITTAAFAEEETVMNSWTETLGVDAGPNKVSLLYGLAWKRFNREANLPHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WMK7</accession>
    <name>A0A0P6WMK7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_18270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064487.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70012">
        <property type="protein sequence ID" value="KPL70012"/>
        <property type="gene ID" value="ADN00_18270"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2960"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010387">
        <property type="entry name" value="QueT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06177">
        <property type="entry name" value="QueT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="202"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="246"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="278" mass="29631" checksum="7C8BB87497AC83F7" modified="2016-01-20" version="1">MREVFRMWKYTRMIILVALSAAIYAAVLIPFKAGIPLIPGITEVRPANVFPVIFGLMFGPAGAWGAAIGNTIGDLFGGSLGWGSLFGFIGNFYLGFIAYKLWGALGLVPKDDMSQNVNKWSKLLAYLIITVVAAAACGVIIAWYLDIIKLVPFAFLAVTITLNNAAAEILLGPPLLLLLYPRVKKWGLIWTDIMDKEDVAPGFARHIGALLMAVGALGGLGVGLGISTGLYGQQILGFTGTQGEVGVWAGVAPFLALIVLASLMLSGREQFVEEAEDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WN17</accession>
    <name>A0A0P6WN17_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_16995</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71396.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL71396">
        <property type="protein sequence ID" value="KPL71396"/>
        <property type="gene ID" value="ADN00_16995"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020258">
        <property type="entry name" value="Uncharacterised_YbeF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10852">
        <property type="entry name" value="DUF2651"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL71396.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="86" mass="9356" checksum="A39B8AD759801135" modified="2016-01-20" version="1">MPWYEDTIFLVIVVFPLALFLAGGILGWLTRRFWVGGVLGFVAAMAFMLLVANETFLIWVFIYSLVGAAGSGLGWGARRLASKTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WN42</accession>
    <name>A0A0P6WN42_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_17235</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064292.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17235"/>
    <dbReference type="EnsemblBacteria" id="KPL71432">
        <property type="protein sequence ID" value="KPL71432"/>
        <property type="gene ID" value="ADN00_17235"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.509"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009384">
        <property type="entry name" value="SwrD-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39185">
        <property type="entry name" value="PTHR39185"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06289">
        <property type="entry name" value="FlbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL71432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="69" mass="7892" checksum="716D0F49A15574EA" modified="2016-01-20" version="1">MILVTRLNGTKFYINAELIRTIESTPDTVITLVDDMKLVVKEAPEIIVERVVEYRRKVRAPFSGIDSLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WPT2</accession>
    <name>A0A0P6WPT2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_16545</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064150.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72081">
        <property type="protein sequence ID" value="KPL72081"/>
        <property type="gene ID" value="ADN00_16545"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014867">
        <property type="entry name" value="Spore_coat_CotH_CotH2/3/7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08757">
        <property type="entry name" value="CotH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="895" mass="98940" checksum="4D0B3414E39D594A" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-08-12" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WPW9</accession>
    <name>A0A0P6WPW9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sugar ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_16330</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72118">
        <property type="protein sequence ID" value="KPL72118"/>
        <property type="gene ID" value="ADN00_16330"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="179"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="71"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL72118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="273" mass="30545" checksum="262D165A9D860088" modified="2016-01-20" version="1">MERKPIKWGKILSYIVLFIFAVIYIGPLFFLVNTSLKTMPEFMKNATALTSQLNFENFAEAWEKANFPQYLLNSLIYTVSATSIYILTAIFVAFPIARGYVKHSGLILTLYVIALFLPPALIPQFQLILNLGLYNNPVGYIMLFLVNPIGIVILVNYVKTIPKELDEAAALDGCGYFQFVTQIVLPLIQPAIATVIVLHAIGIWNEIIAPTIYLTNKDYYPITRGLINFQGVYGSNWPTLAAAVLMLTFPMLILFLFLQRYIISGLTSGAVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WQ13</accession>
    <name>A0A0P6WQ13_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Dihydroorotate dehydrogenase</fullName>
            <ecNumber evidence="5">1.3.98.1</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_17750</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Pyrimidine metabolism; UMP biosynthesis via de novo pathway.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.98.1" evidence="5"/>
    <dbReference type="EMBL" id="LGCL01000043">
        <property type="protein sequence ID" value="KPL70889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064390.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000043.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17750"/>
    <dbReference type="EnsemblBacteria" id="KPL70889">
        <property type="protein sequence ID" value="KPL70889"/>
        <property type="gene ID" value="ADN00_17750"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2142"/>
    <dbReference type="UniPathway" id="UPA00070"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990663">
        <property type="term" value="F:dihydroorotate dehydrogenase (fumarate) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005720">
        <property type="entry name" value="Dihydroorotate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012135">
        <property type="entry name" value="Dihydroorotate_DH_1_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01180">
        <property type="entry name" value="DHO_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000164">
        <property type="entry name" value="DHO_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHO_dh" evidence="4">
        <location>
            <begin position="6"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL70889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="335" mass="37095" checksum="1F58CAF9AAF29933" modified="2016-01-20" version="1">MVDLSSKYMGLQLKNPLVASASPLSKKVGTIRKLEDQGISAVVMYSLFEEQINHASRELDYFLNLGTESFAEALTYFPEMQTYNVGPENYLDLIRKAKEAVQIPIIASLNGISSGGWVKYAKSIEEAGADALELNIYFVPTATETDSQQLEDAYVNLVYDVSEQIRIPLAVKISPYYTALPHFLSRLVKAGAKGLVLFNRFYQPDLDIENFEVQPSLHLSTSEDLRLPLRWIAILYGRLNASLALTSGVHTAQDAAKAIMAGADVAMMASELVEKGPGRVSEILVELQAWMEGKEYASVSQMRGSMSQKSVAQPAVFERANYMKALSTFDNRLKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WSC3</accession>
    <name>A0A0P6WSC3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sulfurtransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_14790</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000036">
        <property type="protein sequence ID" value="KPL73060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063807.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000036.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14790"/>
    <dbReference type="EnsemblBacteria" id="KPL73060">
        <property type="protein sequence ID" value="KPL73060"/>
        <property type="gene ID" value="ADN00_14790"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAO" evidence="1">
        <location>
            <begin position="10"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL73060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="388" mass="42840" checksum="58304B4BCFBB4853" modified="2016-01-20" version="1">MNPSHTTTHDIIIIGAGSVGLPAAFYASKAGYHVLVIDQEASVGQQSNKKAIGGIRATHSDPAKIRLCQRSLEIFSTWQSVYGDSIEWAQGGYCFVAYRSEEENTLKQLLEKQKQYQLNIDWLPARELLEVVPDLNPAGLHGGTYSPKDGSASPLKMAAAFYDHSARQGVQFRFSERVLEITQVSGRVTGVRTDKGNYAAPIVINAAGAQARQIAALVGEDLPIFPDSHEAAVTEPVAPFLKPMIVDIRPMPGSSNFYFYQHVTGQLLFCLTPSPQIWGTDSRETSSFLPQVASRMIQVMPRLKHIRVRRTWRGLYPMTPDGFPIVGWSRNTEGFLHLAGMCGQGFMLGPALGELTTRILTQQLSPDDQETLSYMEPIRAFTSQEVLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WY78</accession>
    <name>A0A0P6WY78_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">4Fe-4S ferredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_16845</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064218.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16845"/>
    <dbReference type="EnsemblBacteria" id="KPL71373">
        <property type="protein sequence ID" value="KPL71373"/>
        <property type="gene ID" value="ADN00_16845"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12838">
        <property type="entry name" value="Fer4_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="5"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="42"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL71373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="80" mass="8366" checksum="4A01E70D8C7C78D0" modified="2016-01-20" version="1">MPAKGRIVVREDFCKACGLCVENCPQGVIGLSADRLNAKGYHPAELIAAGCTGCGICATVCPEAAIEVYRELQHADKTAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZ45</accession>
    <name>A0A0P6WZ45_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_12985</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000028">
        <property type="protein sequence ID" value="KPL75300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063450.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000028.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL75300">
        <property type="protein sequence ID" value="KPL75300"/>
        <property type="gene ID" value="ADN00_12985"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL75300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="148" mass="16920" checksum="724A702DE1C784E5" modified="2016-01-20" version="1">MTTTLESERLRILLDAAQQNCREEILADAKAAADNKLKEISTAQWNGIAELARNPSYGIEGIQKELLDRSEKRWSNETPIPASDTGTNEDELNNFLEKLKSQSQQEIEKICLQIPLTDMQKEELIQKLYLSNLREYLLALVEYHRATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZ87</accession>
    <name>A0A0P6WZ87_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_16585</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064157.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72089">
        <property type="protein sequence ID" value="KPL72089"/>
        <property type="gene ID" value="ADN00_16585"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01547">
        <property type="entry name" value="SBP_bac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132720" evidence="1">
        <location>
            <begin position="25"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="475" mass="51879" checksum="02436777A6CC4305" modified="2016-01-20" version="1">MKNKALPFVIVMIAALILGACAPAAPEAAPTPETIVVKEEVVVTQVVEVPAEPVDKVVVEFWMDEPEEPRVRAYEEIAARFMEEHPEIDVRIVPIEEAGQAQRIATAMAANRLPDLVRMGVQDAATFAADGLLDLDAATAVIEKVGLDDFRTGPLTMVTDPATGKYNSIPYDGWLQAIWYRSDVFEEAGLEAPVTWDAINAACDSIPGTGNMLYAIGLGTNPGENYGHQLFEQVAISNNAWPIDEEGNVTMNTPEMIAALKFYTDLQRCAIPGPQHWLGARQAYELDQSSMLIYSTYIMDDLVDGSDNEDGTYTDLAVADLAAKTGFAPSMEGPNGSASFGQLAVVGVMKDADPEAQLVAEYFMTEGYQEILALSPWGKIPVLKTAVEDWKTLSPYFEKYPPETLEQIANGYDVMQRWLFRGDYDATERAVIGDIEGRLLIPTAISNIALEGTMTPETAAAWLQEQVEALLADRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZJ1</accession>
    <name>A0A0P6WZJ1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ParB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_15575</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063952.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72236">
        <property type="protein sequence ID" value="KPL72236"/>
        <property type="gene ID" value="ADN00_15575"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003115">
        <property type="entry name" value="ParB/Sulfiredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036086">
        <property type="entry name" value="ParB/Sulfiredoxin_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00470">
        <property type="entry name" value="ParB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110849">
        <property type="entry name" value="SSF110849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ParB" evidence="1">
        <location>
            <begin position="7"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="222" mass="24365" checksum="C1CC348575FF9E81" modified="2016-01-20" version="1">MASPFVEIVPTDSVVITEESTRLNLSPEDYAALKANVSEHGVVYPLTVDKNLCVLDYVELAQACKELGFPHIPVVVYENGARTVLSRDELRMSVAQNIAHQAVVGFRDNVEAAFTPIVKSISAAISNFTQSVSGDIQPFVEAVSEYLESHPELLDPAVSDDEDEEISQDELEDEGVDLIASGYEWVCPKCDWKNDEFEVTETVTCKSCGATFKVDDYNHAVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X1J9</accession>
    <name>A0A0P6X1J9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_13220</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063494.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000031.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13220"/>
    <dbReference type="EnsemblBacteria" id="KPL74803">
        <property type="protein sequence ID" value="KPL74803"/>
        <property type="gene ID" value="ADN00_13220"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1126"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="2"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL74803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="348" mass="38111" checksum="75BD281CC5F4371E" modified="2016-01-20" version="1">MLEIDQITKDYDGQPLLRGVSFSVRRGETLCLLGASGSGKSTLLRIIAGLEDAKSGEIRWDGEDISRVPVHERQFGLMFQDYALFPHRSVAQNVAFGLKMQKISEEETAQRVSEALAQVNMQAFASRRVTDLSGGEQQRVALARALAPRPRLLMLDEPLGALDRTLRERLVGELRELLHQTQIPAIYVTHDQEEAFTLGDRLVLISDGMVVQAGTPEEIYARPASGWVARFLGLTNILSGVVEATQPLVVQTELGRLVSSAPDCGEPRVGGVVEVLIKPTARVAGKGEQGANCVQGEVMDSVFRGEFQSILLRCQPGLVFQFHVRQSLRVGERVTLCLPEDGVICLQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X250</accession>
    <name>A0A0P6X250_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF218 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_14645</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000035">
        <property type="protein sequence ID" value="KPL73576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063776.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000035.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL73576">
        <property type="protein sequence ID" value="KPL73576"/>
        <property type="gene ID" value="ADN00_14645"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2095"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06259">
        <property type="entry name" value="YdcF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003848">
        <property type="entry name" value="DUF218"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02698">
        <property type="entry name" value="DUF218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="domain" description="DUF218" evidence="2">
        <location>
            <begin position="78"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL73576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="264" mass="28674" checksum="FBB0DF82EB910305" modified="2016-01-20" version="1">MFVFLSKLLPPLVYPLGLACLLLGAALMFGKKKDGWRWWVTAALVVLVIGGNRWVSNALVRSLEWQYLPQGEIPSAEAIVLLGGGTSAAEPPRPMVELNGAGDRVLYAGKLYKEGRAPLILLSGGNITWLTGEEGSPAEDMAALLALMDIPQEDLLLQTRSQNTYEDALYSSELLKERGITRVILVTSAMHMPRSVALFEKQGIEVIPAPVDFRVTEAGWAQMFSKSVGGFLVDLLPNASNLGAVSSALKEYIGMLVYALRGWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X2N1</accession>
    <name>A0A0P6X2N1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_10105</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062881.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76936">
        <property type="protein sequence ID" value="KPL76936"/>
        <property type="gene ID" value="ADN00_10105"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2484"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035205">
        <property type="entry name" value="DUF5320"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17253">
        <property type="entry name" value="DUF5320"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="106" mass="11188" checksum="85043CB29AD78089" modified="2016-01-20" version="1">MPRGDRTGPAGLGPMTGRRAGYCAGFNAPGFTGGAGRWGGFGFGGRGMGRGWRNMGYAAGVPGWQWFGGAPVPPAQEETEYLKSQASWLKDQLAAIEKRIEELGHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X2Q0</accession>
    <name>A0A0P6X2Q0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Adenine deaminase</fullName>
            <shortName evidence="1">ADE</shortName>
            <ecNumber evidence="1">3.5.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Adenine aminohydrolase</fullName>
            <shortName evidence="1">AAH</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_13125</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenine + H(+) + H2O = hypoxanthine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:23688"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:17368"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenine deaminase type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.2" evidence="1"/>
    <dbReference type="EMBL" id="LGCL01000029">
        <property type="protein sequence ID" value="KPL75296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063478.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000029.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13125"/>
    <dbReference type="EnsemblBacteria" id="KPL75296">
        <property type="protein sequence ID" value="KPL75296"/>
        <property type="gene ID" value="ADN00_13125"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2902"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000034">
        <property type="term" value="F:adenine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006146">
        <property type="term" value="P:adenine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043103">
        <property type="term" value="P:hypoxanthine salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01320">
        <property type="entry name" value="ADA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01962">
        <property type="entry name" value="Adenine_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001365">
        <property type="entry name" value="A_deaminase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028892">
        <property type="entry name" value="ADE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006330">
        <property type="entry name" value="Ado/ade_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43114">
        <property type="entry name" value="PTHR43114"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00962">
        <property type="entry name" value="A_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01430">
        <property type="entry name" value="aden_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="A_deaminase" evidence="2">
        <location>
            <begin position="9"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="197"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="16"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="275"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="276"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="1">
        <location>
            <position position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL75296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="336" mass="38170" checksum="D30108193DC073E6" modified="2016-01-20" version="1">MEAFIHGLPKAELHLHIEGTLEPELMFDLAKRNGIKLAYPSVEAVRQAYQFSNLQDFLDIYYAGAAVLQTEQDFYDLTWAYLQKAHSQTVRHTEIFFDPQTHTARGIPFSTVINGIHRALQDAHQQMGITSQLILCFLRHLSAEEAMRTLEEALPYNAWIAGVGLDSSEKGHPPSKFVDVFQRARQEGWRIVAHAGEEGPAQYVWEALDLLGVQRIDHGVRSTDDPRLIDRLVREGVALTVCPLSNIKLRVFDRMEHHNLKTMLEQGVRVTINSDDPAYFGGYMDENFTAAQQALGLNKDQLGQISRNAFEASFVSEARRKELMFELERYLAKNAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X327</accession>
    <name>A0A0P6X327_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_12730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75507.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063398.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000027.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12730"/>
    <dbReference type="EnsemblBacteria" id="KPL75507">
        <property type="protein sequence ID" value="KPL75507"/>
        <property type="gene ID" value="ADN00_12730"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL75507.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="182" mass="21124" checksum="8526B2881273020E" modified="2016-01-20" version="1">MEISTARLRLREFLASDAPAVLRYQNDPEYLKFYEWESRTPQEVQEFINLFLDWQAETPRSKFQLAITLRQSGKLIGNVGIRQMTAESREADLGYELDPQYWGMGYASEAAHAMLDFAFTTLGILTVTAEVIAENQRSQRVLERMGMQLTQRSQADQYFKGRWWDTLHYALPSRDWTPASNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X3U8</accession>
    <name>A0A0P6X3U8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_08745</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000022">
        <property type="protein sequence ID" value="KPL77668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062613.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000022.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77668">
        <property type="protein sequence ID" value="KPL77668"/>
        <property type="gene ID" value="ADN00_08745"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL77668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="158" mass="18494" checksum="0F08DD2DDA40EE2C" modified="2016-01-20" version="1">MTMNDPQQALFFFRKVVFCLYREAGAMNESTHEELAKKAHLKTSFFHGARKRMAAQLYHDIKKETQTRRILTPFMLRTGLNLEDLQQLFAEGNWQGKFKKIFQGGPRWARIAEEAIRLRDAIDKEDWPAALLVTHTMKGMKTNNGFLIDEFELTDRNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X4H8</accession>
    <name>A0A0P6X4H8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063492.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000031.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13205"/>
    <dbReference type="EnsemblBacteria" id="KPL74801">
        <property type="protein sequence ID" value="KPL74801"/>
        <property type="gene ID" value="ADN00_13205"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1122"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030975">
        <property type="term" value="F:thiamine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015888">
        <property type="term" value="P:thiamine transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13545">
        <property type="entry name" value="PBP2_TbpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005948">
        <property type="entry name" value="ThiB-like"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01254">
        <property type="entry name" value="sfuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132827" evidence="1">
        <location>
            <begin position="23"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="356" mass="38787" checksum="9698FB17C4FEEC62" modified="2016-01-20" version="1">MKQKWNIVWALAALALVLSACAAPQAAETPAAAPLELTVMTHDSFAVSEEVIAEFEAANQVKVVFLKSGDTGSVLNRAILSKDAPLADVLYGVDNTFLSRALEADIFEAYESAGSEGVAAEFRLDPQNRLTPVDYGDVCINYDKAYFAEKGLALPQSLDDLLKPEYKGLLVVQNPATSSPGLAFLLATVAEYGEDGYLDFWAALRANGVVVVNDWETAYYTNFSASTGKGEQPMVVSYGSSPPVEVVYAEQPLDDAPTASLVGDNMCFRQVEFVGVLKGAKNPEAARKFVDFMLSKRFQEDMPLQMFVFPVLAEASLPDVFVKYAQMPQVPAALDPQLIADNREKWIDAWDEVVLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X4J0</accession>
    <name>A0A0P6X4J0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_11235</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MEMO1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76531.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063107.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11235"/>
    <dbReference type="EnsemblBacteria" id="KPL76531">
        <property type="protein sequence ID" value="KPL76531"/>
        <property type="gene ID" value="ADN00_11235"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07361">
        <property type="entry name" value="MEMO_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002737">
        <property type="entry name" value="MEMO1_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11060">
        <property type="entry name" value="PTHR11060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01875">
        <property type="entry name" value="Memo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76531.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="283" mass="30678" checksum="EB2BAE77A2D72558" modified="2016-01-20" version="1">MSTSSDTRPSPIAGVWYSGDPGTLAFEIDQYIEDAHLPELEGEVIAVISPHAGYRYSGRTAGYAFRAVRGLAPRIVAVVSPYHNYHTAALLTSAHQAYKTPLGEVPVDQESLKQFLQLLQARGMTSVKALYQDREHSLEIELPFLQRALAQPFSLLPVMLRSRTAAQVELVGKALADVLRGKPALMVASTDLSHFYPEDTANALDHEIMHQMELFSPQGVLEIEEQGRGFACGGAAVAAVLWAARELGATQVRVVHHSTSGDETQDTTSVVGYGAAVVLKQVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X4J9</accession>
    <name>A0A0P6X4J9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pyruvate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_11340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063128.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11340"/>
    <dbReference type="EnsemblBacteria" id="KPL76549">
        <property type="protein sequence ID" value="KPL76549"/>
        <property type="gene ID" value="ADN00_11340"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.967"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transket_pyr" evidence="1">
        <location>
            <begin position="4"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="328" mass="35786" checksum="9890F4FD8D03E7F7" modified="2016-01-20" version="1">MREITYAEALREAMRQAMQKDQRVFLMGEDIGVYGGAFGVTAGLVEEFGEKRVRDTPISEAAITGACVGAALTGMRPIGEMQFSDFVVLAMEQLVMQAAKIRFMFGGKASVPMIMRLASGSGTGAAAQHSESLENWFVHTPGLKVVMPSTPYDAKGLLLAALDDENPVIFMEHKVLYRTKGPVPEEMYQIPLGKSHVVREGKHLTVVAMSIMVSRALEAAEILAKEGIELEIIDPRTLSPLDDEPIIQSVMKTGKALVVHEAVKTGGFGGEVVSRIVESKAFGYLDAPVRRLAGLDIPIPYNRTLERAAVPQVENIVAEARKLVEWKY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X4K1</accession>
    <name>A0A0P6X4K1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">V4R domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_11415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11415"/>
    <dbReference type="EnsemblBacteria" id="KPL76558">
        <property type="protein sequence ID" value="KPL76558"/>
        <property type="gene ID" value="ADN00_11415"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024096">
        <property type="entry name" value="NO_sig/Golgi_transp_ligand-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004096">
        <property type="entry name" value="V4R"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02830">
        <property type="entry name" value="V4R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00989">
        <property type="entry name" value="V4R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111126">
        <property type="entry name" value="SSF111126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="V4R" evidence="1">
        <location>
            <begin position="129"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="225" mass="24687" checksum="687E3D9398305432" modified="2016-01-20" version="1">MIARLSALRLLVGHPGMLAILRRAGLTDSLAGLLVNNWEKTFPYAAYQKIIAAVREIYGERGYRALAYRAGKNSFAETFGGLPAVKTAKEQLAQMGDERLRLHLAMQTLAEAMEGTSIQRVEVSLRGLSASLRVDFCFECWDSPLTHEPICYGLVGSARGALAYLLGRDDYLVREVHCTAAGDDFCELEIKPPPEAMRGRGLGQTGFLTLPPDLRAGVDEDTQEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X4L2</accession>
    <name>A0A0P6X4L2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Primosomal protein N'</fullName>
            <ecNumber evidence="9">3.6.4.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ATP-dependent helicase PriA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">priA</name>
        <name evidence="11" type="ORF">ADN00_11225</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the primosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the helicase family. PriA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="9"/>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063167.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11225"/>
    <dbReference type="EnsemblBacteria" id="KPL76585">
        <property type="protein sequence ID" value="KPL76585"/>
        <property type="gene ID" value="ADN00_11225"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.942"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990077">
        <property type="term" value="C:primosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006269">
        <property type="term" value="P:DNA replication, synthesis of RNA primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006268">
        <property type="term" value="P:DNA unwinding involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00983">
        <property type="entry name" value="PriA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005259">
        <property type="entry name" value="PriA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041222">
        <property type="entry name" value="PriA_3primeBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042115">
        <property type="entry name" value="PriA_3primeBD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041236">
        <property type="entry name" value="PriA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040498">
        <property type="entry name" value="PriA_CRR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17764">
        <property type="entry name" value="PriA_3primeBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18074">
        <property type="entry name" value="PriA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18319">
        <property type="entry name" value="PriA_CRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00595">
        <property type="entry name" value="priA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6 9" id="KW-0347">Helicase</keyword>
    <keyword evidence="5 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 9" id="KW-0639">Primosome</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="9" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="10">
        <location>
            <begin position="299"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="9">
        <location>
            <begin position="555"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="9">
        <location>
            <begin position="582"/>
            <end position="598"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL76585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="841" mass="93645" checksum="545DC27CCEB14D06" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X539</accession>
    <name>A0A0P6X539_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_18100</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0394 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL69985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064452.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL69985">
        <property type="protein sequence ID" value="KPL69985"/>
        <property type="gene ID" value="ADN00_18100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007272">
        <property type="entry name" value="Sulf_transp"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04143">
        <property type="entry name" value="Sulf_transp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="69"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="162"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="193"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="247"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="276"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="307"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="domain" description="Sulf_transp" evidence="8">
        <location>
            <begin position="19"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF04143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL69985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="333" mass="35470" checksum="CD7947061D92D97C" modified="2016-01-20" version="1">MSILLGLLTGVAFGFVLQRGRVCFNSAFRDLRMMKDNFMFKAGLLAIAVQIIAFLAMSQLGLIHLNPKPLNLIGSIVGGYIFGLGMVLAGGCASGTTYRISEGNTTAWLAGLVYGIFAWATQSGFLSPLMKAISQFNITVAPNSALYLGEQTGPTLATMLNINPWIAGLVVAALLFAYLFGTKTTPRDTATWGWIKTGLLVVPVAMFGFWSSTISGRPYGLGITGGWINILKAIQTNELLNWEGAEVLGIMIGAGITAVIFKEFKLRVPKNGKTFLYVVAGGVLMGFGAVFAGGCNIGHFLTGIPQLAISSIVAGIFFILGNWTMVRILYGKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X550</accession>
    <name>A0A0P6X550_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Probable membrane transporter protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_18230</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the 4-toluene sulfonate uptake permease (TSUP) (TC 2.A.102) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064478.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18230"/>
    <dbReference type="EnsemblBacteria" id="KPL70004">
        <property type="protein sequence ID" value="KPL70004"/>
        <property type="gene ID" value="ADN00_18230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002781">
        <property type="entry name" value="TM_pro_TauE-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01925">
        <property type="entry name" value="TauE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="5"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="188"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="212"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="240"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363041"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL70004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="263" mass="27249" checksum="CC6B307B5BE3744B" modified="2016-01-20" version="1">MNTFYIVAIIFVLTVVMIMSGRGGGNFYVAAFVLLSVPMHTASTTSQFVLLASALVGAIVFGKARTMSWPLAIFFGGLNASMAFVGGFVAHSFDGTLLKIILSVLLFVAGVAMLFPEKQAHKTAVSRFGYWNIREGDNLYVINLWVAVPLTLATGFFSGMVGISGGSFLVPLMVVGCGVPMRTAVGTATAMLAATALTGFTGNALHGGFDPALALPCGAVAVIGGLIGSKIALKTKPKSLKTISGILTNLAAIFMLVNTISGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5I1</accession>
    <name>A0A0P6X5I1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Release factor glutamine methyltransferase</fullName>
            <shortName evidence="5">RF MTase</shortName>
            <ecNumber evidence="5">2.1.1.297</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">N5-glutamine methyltransferase PrmC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Protein-(glutamine-N5) MTase PrmC</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Protein-glutamine N-methyltransferase PrmC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">prmC</name>
        <name evidence="8" type="ORF">ADN00_18495</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">Methylates the class 1 translation termination release factors RF1/PrfA and RF2/PrfB on the glutamine residue of the universally conserved GGQ motif.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-methionine = H(+) + N(5)-methyl-L-glutaminyl-[peptide chain release factor] + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42896"/>
            <dbReference type="Rhea" id="RHEA-COMP:10271"/>
            <dbReference type="Rhea" id="RHEA-COMP:10272"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30011"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61891"/>
            <dbReference type="EC" id="2.1.1.297"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the protein N5-glutamine methyltransferase family. PrmC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.297" evidence="5"/>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18495"/>
    <dbReference type="EnsemblBacteria" id="KPL70168">
        <property type="protein sequence ID" value="KPL70168"/>
        <property type="gene ID" value="ADN00_18495"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3007"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102559">
        <property type="term" value="F:protein-(glutamine-N5) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036009">
        <property type="term" value="F:protein-glutamine N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018364">
        <property type="term" value="P:peptidyl-glutamine methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02126">
        <property type="entry name" value="RF_methyltr_PrmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004556">
        <property type="entry name" value="HemK-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040758">
        <property type="entry name" value="PrmC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019874">
        <property type="entry name" value="Release_fac_Glu-N5_MeTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007848">
        <property type="entry name" value="Small_mtfrase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05175">
        <property type="entry name" value="MTS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17827">
        <property type="entry name" value="PrmC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00536">
        <property type="entry name" value="hemK_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03534">
        <property type="entry name" value="RF_mod_PrmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PrmC_N" evidence="7">
        <location>
            <begin position="5"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="MTS" evidence="6">
        <location>
            <begin position="115"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="5">
        <location>
            <begin position="120"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF05175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF17827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL70168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="279" mass="30531" checksum="5EC343239F0898CB" modified="2016-01-20" version="1">MTIRQWLETARQRLNGRQDEPALSARLLTAHHLNKDRAWIIAHNHDPLPADLIPALEADLDRLVRGVPLPYVLGAWEFYGLSFQVNESVLIPRPETELLVETALNWVKQHPGPLRAADVGTGSGCIAAALARHAPQMHITAVDISLQALRVAKQNFIQLNVAGQVSALQSDLLSSLSGPFDLLCANLPYIPSAKLPHLDVTTHEPSLALDGGPDGLVLVQELLLQARSRMADRFLILLEVEADHGQAAPELACQIFPQANTTMLRDLAGLPRLVSIKFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X6G3</accession>
    <name>A0A0P6X6G3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_05195</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78655.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061913.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05195"/>
    <dbReference type="EnsemblBacteria" id="KPL78655">
        <property type="protein sequence ID" value="KPL78655"/>
        <property type="gene ID" value="ADN00_05195"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1511"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003748">
        <property type="entry name" value="DUF169"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37954">
        <property type="entry name" value="PTHR37954"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02596">
        <property type="entry name" value="DUF169"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78655.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="256" mass="27952" checksum="05C44FBA88CF5ADF" modified="2016-01-20" version="1">MQAKEISESIVRILHLETEPVAVKMYKDRKDLPKHPQNIKQNFCQLVSIARYQGRGNSSTADNMICAFGAACLGLIETPEVISSGKAAVGIYTGTQEAAKNFMSNAFKIGDTGREYDAVMVKPLSEVEESDEPDAVIMYVNPAQAMRLIHSCAYDTGEKITADTVAEGAMCSCTGFSIAKQKPTVGFPCAGDRIFGGTQNHELVFTAPYSLVKEKLVDRLEKTAAGGFSVFPVPPNMHWTPMMPPAYTVQPEYLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7D5</accession>
    <name>A0A0P6X7D5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Metallophos_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_18615</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallophosphoesterase superfamily. YfcE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064544.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18615"/>
    <dbReference type="EnsemblBacteria" id="KPL70062">
        <property type="protein sequence ID" value="KPL70062"/>
        <property type="gene ID" value="ADN00_18615"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024654">
        <property type="entry name" value="Calcineurin-like_PHP_lpxH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011152">
        <property type="entry name" value="Pesterase_MJ0912"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12850">
        <property type="entry name" value="Metallophos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000883">
        <property type="entry name" value="Pesterase_MJ0912"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos_2" evidence="2">
        <location>
            <begin position="1"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL70062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="242" mass="27418" checksum="E419C786829A0999" modified="2016-01-20" version="1">MKVLIISDIHANLTALEAVLADCGSFDAVWCLGDVVGYGPDPNECVELVRSLPNLVCILGNHDAAALGELELESFNYDAQLSTLWTQQTLTETNRRFLLKLPEAQTLDQVTLAHGSPRNPVWEYVLDTYTARANFQFFSTPFCFVGHSHLPLAFFQKEDQSEVMMQIFHEDQTITLKPRAIINPGSVGQPRDHDPRSSYAIYDTTSQRWEFRRASYAVSTVQERIRRAGLPDRHALRLSYGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X8B1</accession>
    <name>A0A0P6X8B1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Transcription termination factor Rho</fullName>
            <ecNumber evidence="8">3.6.4.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">ATP-dependent helicase Rho</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rho</name>
        <name evidence="11" type="ORF">ADN00_11210</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Facilitates transcription termination by a mechanism that involves Rho binding to the nascent RNA, activation of Rho's RNA-dependent ATPase activity, and release of the mRNA from the DNA template.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homohexamer. The homohexamer assembles into an open ring structure.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the Rho family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.-" evidence="8"/>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063103.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11210"/>
    <dbReference type="EnsemblBacteria" id="KPL76529">
        <property type="protein sequence ID" value="KPL76529"/>
        <property type="gene ID" value="ADN00_11210"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.938"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008186">
        <property type="term" value="F:ATP-dependent activity, acting on RNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04459">
        <property type="entry name" value="Rho_CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01884">
        <property type="entry name" value="Rho"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011129">
        <property type="entry name" value="CSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011112">
        <property type="entry name" value="Rho_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036269">
        <property type="entry name" value="Rho_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011113">
        <property type="entry name" value="Rho_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004665">
        <property type="entry name" value="Term_rho"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46425">
        <property type="entry name" value="PTHR46425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07498">
        <property type="entry name" value="Rho_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07497">
        <property type="entry name" value="Rho_RNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00357">
        <property type="entry name" value="CSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00959">
        <property type="entry name" value="Rho_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF68912">
        <property type="entry name" value="SSF68912"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00767">
        <property type="entry name" value="rho"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51856">
        <property type="entry name" value="RHO_RNA_BD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8" id="KW-0347">Helicase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="6 8" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1 8" id="KW-0806">Transcription termination</keyword>
    <feature type="domain" description="Rho RNA-BD" evidence="10">
        <location>
            <begin position="48"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="163"/>
            <end position="168"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="175"/>
            <end position="180"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51856"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL76529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="423" mass="47510" checksum="E0355CF8416FDC5B" modified="2016-01-20" version="1">MEILELEKAPLEELRNIASTMDVPNARRLKKEMLLVKIRQAEAAREGLEVRGGILEIMNEGIGFLRANYQVSNEDVYVSQAQLRRHSLRNGDLVIGHVRPPRDTERHYGLVKVETINGQNPEESRRRPTFESLTPIFPEQRYDLEVDHGALSNRLINLIAPIGRGQRGMIVSPPKAGKTTIMKEIANAISTNYPDVHMIISLIGERPEEVTDMDRSVEAEVVASTFDEPVNAHVRSAEMTLERAKRLVEIGRHVVILMDSLTRLARAYNLVVNPSGRTLSGGMDPSALYPPKRFFGAARNIEEGGSLTIIATALVDTGSRLDDVVYEEFKGTGNMEMHLSRRLQERRIFPAIDIEKSSTRREELLLGPDVLQRVWLMRRMYLQMIATPPQGAGMDQAVAAEAILQRLAKTKTNMEFLETLADS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X937</accession>
    <name>A0A0P6X937_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Type I restriction enzyme endonuclease subunit</fullName>
            <shortName evidence="10">R protein</shortName>
            <ecNumber evidence="10">3.1.21.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">ADN00_02590</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Subunit R is required for both nuclease and ATPase activities, but not for modification.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>Endonucleolytic cleavage of DNA to give random double-stranded fragments with terminal 5'-phosphates, ATP is simultaneously hydrolyzed.</text>
            <dbReference type="EC" id="3.1.21.3"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">The type I restriction/modification system is composed of three polypeptides R, M and S.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the HsdR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.21.3" evidence="10"/>
    <dbReference type="EMBL" id="LGCL01000012">
        <property type="protein sequence ID" value="KPL79423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02590"/>
    <dbReference type="REBASE" id="132865">
        <property type="entry name" value="OapP3M1ORF2580P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79423">
        <property type="protein sequence ID" value="KPL79423"/>
        <property type="gene ID" value="ADN00_02590"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2344"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009035">
        <property type="term" value="F:type I site-specific deoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007409">
        <property type="entry name" value="Restrct_endonuc_type1_HsdR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004473">
        <property type="entry name" value="Restrct_endonuc_typeI_HsdR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040980">
        <property type="entry name" value="SWI2_SNF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021810">
        <property type="entry name" value="T1RH-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11867">
        <property type="entry name" value="DUF3387"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04313">
        <property type="entry name" value="HSDR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18766">
        <property type="entry name" value="SWI2_SNF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00348">
        <property type="entry name" value="hsdR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="12" id="KW-0347">Helicase</keyword>
    <keyword evidence="7 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0680">Restriction system</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="11">
        <location>
            <begin position="309"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU364115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KPL79423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="1046" mass="118445" checksum="625C7B17A77643AC" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X964</accession>
    <name>A0A0P6X964_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">30S ribosomal protein S17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rpsQ</name>
        <name evidence="6" type="ORF">ADN00_12555</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">One of the primary rRNA binding proteins, it binds specifically to the 5'-end of 16S ribosomal RNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the universal ribosomal protein uS17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063361.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12555"/>
    <dbReference type="EnsemblBacteria" id="KPL76158">
        <property type="protein sequence ID" value="KPL76158"/>
        <property type="gene ID" value="ADN00_12555"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01345_B">
        <property type="entry name" value="Ribosomal_S17_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019984">
        <property type="entry name" value="Ribosomal_S17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000266">
        <property type="entry name" value="Ribosomal_S17/S11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019979">
        <property type="entry name" value="Ribosomal_S17_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10744">
        <property type="entry name" value="PTHR10744"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00366">
        <property type="entry name" value="Ribosomal_S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00973">
        <property type="entry name" value="RIBOSOMALS17"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03635">
        <property type="entry name" value="uS17_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00056">
        <property type="entry name" value="RIBOSOMAL_S17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 4 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 3 5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL76158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="91" mass="10480" checksum="84CC50A556C0D221" modified="2016-01-20" version="1">MTTTRRRLTGVVTSNKMMKTVVVEIARTYRHPLYKKVVHATKRVKAHDELGCMIGDEVQIIESRPLSREKRWVVETITKRIGETSDVVEGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9Z8</accession>
    <name>A0A0P6X9Z8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nitrate ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_11425</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063144.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11425"/>
    <dbReference type="EnsemblBacteria" id="KPL76560">
        <property type="protein sequence ID" value="KPL76560"/>
        <property type="gene ID" value="ADN00_11425"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.985"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018632">
        <property type="entry name" value="AAA-associated_dom_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09821">
        <property type="entry name" value="AAA_assoc_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="8"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="44"/>
            <end position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL76560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="436" mass="48365" checksum="98194F7E55BE7BC3" modified="2016-01-20" version="1">MKNEKLLLEVKNVSQIYGSGTRKFTAIENINLTLQEGVFVSLLGPSGCGKSTLLRIITGLQKPTEGQVLYRGMQLQGVNPHASIVFQTFALFPWLNVQENVELALKVKGIPSEQRTKHSVELLDRVGLDGFENAFPRELSGGMRQKVGFARAMAVEPELLCLDEPFSALDVLSAETLRGELLELWLSGSIPTLAILMVSHNIEEAVLMSDRIVVMDKNPGRIIADIKIDLAHPRARKSPEFQHIVDQVYALLAGQTQPDALELGSAPGEPGPTRRLPQMAISDLSGFLEMLNDIPEQKTDLFRLAEGSNMDSDYILRLADAAELLGFAKVTKGDVELTPLGETFAEARILARKEIFATRIRRIPFFQWLLTMLRASDRQRIKWDVVQAALELEFPPDEAERQLDIAVDWGRYAEILAYDDGDGVIFLESATATVAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XA74</accession>
    <name>A0A0P6XA74_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Methylthioribose-1-phosphate isomerase</fullName>
            <shortName evidence="2">M1Pi</shortName>
            <shortName evidence="2">MTR-1-P isomerase</shortName>
            <ecNumber evidence="2">5.3.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">S-methyl-5-thioribose-1-phosphate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">mtnA</name>
        <name evidence="3" type="ORF">ADN00_03505</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the interconversion of methylthioribose-1-phosphate (MTR-1-P) into methylthioribulose-1-phosphate (MTRu-1-P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>S-methyl-5-thio-alpha-D-ribose 1-phosphate = S-methyl-5-thio-D-ribulose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:19989"/>
            <dbReference type="ChEBI" id="CHEBI:58533"/>
            <dbReference type="ChEBI" id="CHEBI:58548"/>
            <dbReference type="EC" id="5.3.1.23"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 1/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the EIF-2B alpha/beta/delta subunits family. MtnA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.23" evidence="2"/>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061580.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03505"/>
    <dbReference type="EnsemblBacteria" id="KPL78972">
        <property type="protein sequence ID" value="KPL78972"/>
        <property type="gene ID" value="ADN00_03505"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.52"/>
    <dbReference type="UniPathway" id="UPA00904">
        <property type="reaction ID" value="UER00874"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046523">
        <property type="term" value="F:S-methyl-5-thioribose-1-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019509">
        <property type="term" value="P:L-methionine salvage from methylthioadenosine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019284">
        <property type="term" value="P:L-methionine salvage from S-adenosylmethionine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01678">
        <property type="entry name" value="Salvage_MtnA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000649">
        <property type="entry name" value="IF-2B-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005251">
        <property type="entry name" value="IF-M1Pi"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042529">
        <property type="entry name" value="IF_2B-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011559">
        <property type="entry name" value="Initiation_fac_2B_a/b/d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027363">
        <property type="entry name" value="M1Pi_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01008">
        <property type="entry name" value="IF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00524">
        <property type="entry name" value="eIF-2B_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00512">
        <property type="entry name" value="salvage_mtnA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="1 2 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="47"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="247"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="237"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="2">
        <location>
            <position position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="349" mass="37884" checksum="CD91044114B7E5EA" modified="2016-01-20" version="1">MVRSLEWDDSSCTLQLLDQRLLPAQVEMVTCENYTKVSTAIQNMTVRGAPVIGAAAAFGMALAACQSAQTTTEGLRADLKKAADVLIASRPTAVNLAWAVQRMLKKASVPASTADDLTQLMIAEAKLIAQEDVETNRRMAEFGAALIEDGDTIIHHCNTGSLATVDWGTALGAIRMAHEQGKKIHVLVDETRPRLQGARLTAWELDQYQIPYHIITDNMSGHFLRSGMVKKVFYGADRVAANGDVCNKIGTYMLSLAAKTNGVPVYAVFPTTTVDLNLKSGDLIPIEERDQEEVLGIEVNGQRVTPQGAKAFNPAFDVTPNDLITALVTENGVIYPPFDINLPRAVEDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XA84</accession>
    <name>A0A0P6XA84_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BTAD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_16475</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16475"/>
    <dbReference type="EnsemblBacteria" id="KPL72070">
        <property type="protein sequence ID" value="KPL72070"/>
        <property type="gene ID" value="ADN00_16475"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13401">
        <property type="entry name" value="AAA_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03704">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01043">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="BTAD" evidence="2">
        <location>
            <begin position="104"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="871"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="911"/>
            <end position="944"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL72070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="1062" mass="120538" checksum="F6C2C36ED3EB9A91" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAN8</accession>
    <name>A0A0P6XAN8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Histidine--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.21</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Histidyl-tRNA synthetase</fullName>
            <shortName evidence="8">HisRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">hisS</name>
        <name evidence="10" type="ORF">ADN00_15505</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-histidine + tRNA(His) = AMP + diphosphate + H(+) + L-histidyl-tRNA(His)</text>
            <dbReference type="Rhea" id="RHEA:17313"/>
            <dbReference type="Rhea" id="RHEA-COMP:9665"/>
            <dbReference type="Rhea" id="RHEA-COMP:9689"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78527"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.21"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3 8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.21" evidence="8"/>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063940.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15505"/>
    <dbReference type="EnsemblBacteria" id="KPL72225">
        <property type="protein sequence ID" value="KPL72225"/>
        <property type="gene ID" value="ADN00_15505"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.803"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004821">
        <property type="term" value="F:histidine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006427">
        <property type="term" value="P:histidyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00773">
        <property type="entry name" value="HisRS-like_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00859">
        <property type="entry name" value="HisRS_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00127">
        <property type="entry name" value="His_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015807">
        <property type="entry name" value="His-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041715">
        <property type="entry name" value="HisRS-like_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004516">
        <property type="entry name" value="HisRS/HisZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033656">
        <property type="entry name" value="HisRS_anticodon"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43707">
        <property type="entry name" value="PTHR43707"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13393">
        <property type="entry name" value="tRNA-synt_His"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001549">
        <property type="entry name" value="His-tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00442">
        <property type="entry name" value="hisS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="9">
        <location>
            <begin position="1"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL72225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="427" mass="48571" checksum="4EAA2C4A8CFBF1ED" modified="2016-01-20" version="1">MKTTIQSVKGTRDFYPEEMGVRSWLYEVIKEVSSQFGYQEYDGPFLEKIDLYAAKSGEELVKEQSFVFQDRSGEDITLRPELTPTLARMVAQRQNQLVFPLRWWSFGPFWRYERPQKGRTREFFQWNIDLIGEDSPEADAELVSVCIYFFQKVGLTPDQVTILVNDRKLMDSELTRLDITPDLKRTVFRLIDRKEKMPIQDWRQYGLDSGLSETQMQGIEALLVDQDLWKKSPDLTRLFEILEAMNLRQYVRFDPQIIRGLEYYTGIVFEAKDQGREGRSILGGGHYGNLVADVGGDPLAGVGFAMGDVMAGIVLEKYGCMPKFEISPAPVMVTVFDDALLPKSFALANSLRLQGLRAAVYPSAGKLQKQFKYADRMGIRYVVVMGPDEEEVGKATIKDLASREQFTVAQAELVLELKKLLANAGAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XCV1</accession>
    <name>A0A0P6XCV1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_07870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000020">
        <property type="protein sequence ID" value="KPL78084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78084">
        <property type="protein sequence ID" value="KPL78084"/>
        <property type="gene ID" value="ADN00_07870"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="26"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="274" mass="30947" checksum="9B966074B35DD302" modified="2016-01-20" version="1">MIKTTKSYFDLGDGQLYYETAGEGMPLVLSHAAFLDSRMFDTIWEPLAKHFHVIRYDMRGFGKSSPVTGALCRRNDLVQMLNHLDVTEAHLVGCSNGGQISLDLALEQPQRFKSLTLVDSTPSGFELQVEPPRYIMEMFDAMQHGDMDRSSELQIRVWLDGEQREPDQVDSTLRKKALEMNRIPVAQNTFFAADMQPASPLTPPAIARLESVNCPTWIVAGALDHCEVLRAADEMVKRIPDARKTIIESSGHVPSYEQPERFVKLLLDFLSRIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XD27</accession>
    <name>A0A0P6XD27_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thymidylate kinase</fullName>
            <ecNumber evidence="3">2.7.4.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">dTMP kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">tmk</name>
        <name evidence="5" type="ORF">ADN00_08660</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>ATP + dTMP = ADP + dTDP</text>
            <dbReference type="Rhea" id="RHEA:13517"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58369"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the thymidylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.9" evidence="3"/>
    <dbReference type="EMBL" id="LGCL01000022">
        <property type="protein sequence ID" value="KPL77657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062598.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000022.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08660"/>
    <dbReference type="EnsemblBacteria" id="KPL77657">
        <property type="protein sequence ID" value="KPL77657"/>
        <property type="gene ID" value="ADN00_08660"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1447"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004798">
        <property type="term" value="F:thymidylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006233">
        <property type="term" value="P:dTDP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006235">
        <property type="term" value="P:dTTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00165">
        <property type="entry name" value="Thymidylate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039430">
        <property type="entry name" value="Thymidylate_kin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018095">
        <property type="entry name" value="Thymidylate_kin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018094">
        <property type="entry name" value="Thymidylate_kinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02223">
        <property type="entry name" value="Thymidylate_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00041">
        <property type="entry name" value="DTMP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01331">
        <property type="entry name" value="THYMIDYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thymidylate_kin" evidence="4">
        <location>
            <begin position="5"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="7"/>
            <end position="14"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL77657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="205" mass="23108" checksum="5E8477518ED7E205" modified="2016-01-20" version="1">MFITLEGPDGSGKSSQIEPLAEYLRQQGFSVITTREPGGTSISNQVRDVLKSMENKSMHPRTEILLFCAARAQLVEEVICPALEKGMIVLSDRYADSTLAYQGYGHGYDLDFLRSLLNFATGGLWPDLTLYLDVDAETGLNRRKSGGGEWNRLDDYALAFHRRVRQGYVELAAQQPQRWVTVDAGQPMQVVQQELRRIVTQRLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDP5</accession>
    <name>A0A0P6XDP5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_08240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062509.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08240"/>
    <dbReference type="EnsemblBacteria" id="KPL77859">
        <property type="protein sequence ID" value="KPL77859"/>
        <property type="gene ID" value="ADN00_08240"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.650"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003797">
        <property type="entry name" value="DegV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043168">
        <property type="entry name" value="DegV_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02645">
        <property type="entry name" value="DegV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00762">
        <property type="entry name" value="DegV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51482">
        <property type="entry name" value="DEGV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="285" mass="30732" checksum="2857CCB0131FF110" modified="2016-01-20" version="1">MSAKVAIVTDSTCGIPDRYLEGLPIYILPLQVIWGESTYQDGIDITPAEFYHALSNTKVMPTTSQVTPAAFMKIYEQLINEGYDILSIHISSRLSGTIDSAIQARANFPGAQIEIVDSLVTSMALGFQVLQIARMAKDGASLQECKQAALQLPERSGATFVVSTLEFLHRGGRIGGASAFLGTALDLKPILELKEGRIEAVERVRTKSKALKRTIELVQSKLNGHKKIHLACLNANAPTEAQILLDEVTKALPAEVVVETVFSEVSPVIGTHTGPGTVGLAFLFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDQ0</accession>
    <name>A0A0P6XDQ0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein translocase subunit SecD</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">secD</name>
        <name evidence="10" type="ORF">ADN00_00970</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Forms a complex with SecF. Part of the essential Sec protein translocation apparatus which comprises SecA, SecYEG and auxiliary proteins SecDF. Other proteins may also be involved.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the SecD/SecF family. SecD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061080.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00970"/>
    <dbReference type="EnsemblBacteria" id="KPL81124">
        <property type="protein sequence ID" value="KPL81124"/>
        <property type="gene ID" value="ADN00_00970"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3593"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015450">
        <property type="term" value="F:protein-transporting ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043952">
        <property type="term" value="P:protein transport by the Sec complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01463_B">
        <property type="entry name" value="SecD_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001036">
        <property type="entry name" value="Acrflvin-R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005791">
        <property type="entry name" value="SecD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022813">
        <property type="entry name" value="SecD/SecF_arch_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022645">
        <property type="entry name" value="SecD/SecF_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022646">
        <property type="entry name" value="SecD/SecF_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30081">
        <property type="entry name" value="PTHR30081"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07549">
        <property type="entry name" value="Sec_GG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02355">
        <property type="entry name" value="SecD_SecF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00702">
        <property type="entry name" value="ACRIFLAVINRP"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00916">
        <property type="entry name" value="2A0604s01"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01129">
        <property type="entry name" value="secD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="277"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="302"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="327"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="380"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="405"/>
            <end position="428"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL81124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="446" mass="48137" checksum="A7F633B7F4C1AD9A" modified="2016-01-20" version="1">MNQRIVRLVLILLLIGLVIWIDLPTNPGIKIGDFSRNLDTVLGLDLQGGMQVLLEVDKPEDYVATEQEMADARAIFENRSNGLGVSEVSFQVAGTRRIVGEFPGLVNTDEVIAVLKETGQLEFVDMGSTPLPAGTVIKTDLDALIPENPIESDNLEDKVWHTVMTGDMLKTVAVTANQLGQPEVAFELKPEGAVIFKDHTSQNQGKYLAIVLDKTVISTPVINAVIEDSGVIQGQFTNEEANNLAIQLRYGSLPIPFKVVESRVVGPTLGADSLNKSIIAGLIGFAIVALFMAIYYRLPGGVAIISIITYALITLALFKLIPVTLTLPGVAGVLLSTGGALDANILIFERLKEELRAGRTIKQALDLAWKRAWPSIRDSNFATIITSVILFWFGSAFGATIVKGFALTLAIGVAVSLFCAIVVTRTLLNETINLTKPKDIGKWFGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XF38</accession>
    <name>A0A0P6XF38_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AP-endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_06235</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062101.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06235"/>
    <dbReference type="EnsemblBacteria" id="KPL78815">
        <property type="protein sequence ID" value="KPL78815"/>
        <property type="gene ID" value="ADN00_06235"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1749"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="1">
        <location>
            <begin position="20"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="304" mass="34555" checksum="798E35F466C8FC12" modified="2016-01-20" version="1">MKLGLFTAAFAKNSLEEVAEWASANAFETLEIACWPVGKANRRYAGVTHIDVNDLTPAKASQILGLLDKHNLQISSLGYYPNPLHPDPDHREQVIGHLKQVILAAEMLKVEVVGTFIGKDKDKTVDANFDDYARIWPPIVKFAKEHGVKIAIENCPMLFSYDEWPGGNNLASTPAIWKRMWEIIPDDNFGLNLDPSHLILQMIDPYRVVREFKDKIFHVHAKDLMIDREGLYQHGALSQGMGWQIPRLPGLGDMDWPKFIAALYQNGYDSFISIEHEDRAFEKTEELVNRGFLIARDVLRPLIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XF45</accession>
    <name>A0A0P6XF45_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FeS_assembly_P domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_06290</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062111.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06290"/>
    <dbReference type="EnsemblBacteria" id="KPL78824">
        <property type="protein sequence ID" value="KPL78824"/>
        <property type="gene ID" value="ADN00_06290"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002744">
        <property type="entry name" value="MIP18-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01883">
        <property type="entry name" value="FeS_assembly_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="SSF117916"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FeS_assembly_P" evidence="1">
        <location>
            <begin position="8"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="99" mass="11008" checksum="93207D0BA9FB1C53" modified="2016-01-20" version="1">MNEKLIGAVLEKLREVMDPETGVDVVRMRLIENLVCDEDGDISYTFRPSSPLCPIAVPLAMEIIQAVSDVPGVNRQHMQVVDYVQADQLNALLKTILQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XHQ4</accession>
    <name>A0A0P6XHQ4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_02995</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000014">
        <property type="protein sequence ID" value="KPL79358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79358">
        <property type="protein sequence ID" value="KPL79358"/>
        <property type="gene ID" value="ADN00_02995"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDZ" evidence="1">
        <location>
            <begin position="271"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="386" mass="40250" checksum="F547BA810ACE282B" modified="2016-01-20" version="1">MSILLLTSLACFSAPQLSQLNLNLPQPAEATPLPPQPLNTAAPLQIADLAAQQDLLVSIYERVSPGVVAIQTLTNEGSGLGSGFVYDKEGHIITNYHVVEGAKELEVDFPSGIKVRGEVIGTDLDSDLAVIKVNLPPEDLTPVPLGDSEQTFVGQTVVAIGNPFGLSGTMTTGIISAKGRTLSSLRQTPEGGVYSAGDILQTDASINPGNSGGPLLNLNGEVIGVNRAIRTTGTTITGDPINSGVGFAVSINIVRRVVPSLINQGGYDYPYIGLTAREELSLLEQESLGLSTNDGKYIAGAYVIEVVSGGPADQAGLRGGSLRQITDTGLPAGGDLIIGVDGRPVRVFGELLSYVMTNKSPGETISVTILRDGQEKEVVITLDKRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XI86</accession>
    <name>A0A0P6XI86_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_02540</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000011">
        <property type="protein sequence ID" value="KPL79577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061388.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000011.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79577">
        <property type="protein sequence ID" value="KPL79577"/>
        <property type="gene ID" value="ADN00_02540"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="80" mass="9121" checksum="317C77CA77E3D923" modified="2016-01-20" version="1">MNQTTSPQIDSTRHTYQISIKGKIALKDWEYWFEGFVLETVSPVETKLIGPIRDQAHLFAVLTKLRDLGISILSVTCLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XJ39</accession>
    <name>A0A0P6XJ39_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH arsR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_02040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000008">
        <property type="protein sequence ID" value="KPL79934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79934">
        <property type="protein sequence ID" value="KPL79934"/>
        <property type="gene ID" value="ADN00_02040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012318">
        <property type="entry name" value="HTH_CRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00419">
        <property type="entry name" value="HTH_CRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="98" mass="10895" checksum="AF7C91EC488B62B9" modified="2016-01-20" version="1">MQNFYTFAEDVAARAQALADPTRLVILRMIRHFGMTNTEIASYLGISRPTVSVHAKILRGAGLIETSEVGRAVQHTIKPAALRQLFTDLQRFLDLPEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XJS6</accession>
    <name>A0A0P6XJS6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MFS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_11945</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063245.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76056">
        <property type="protein sequence ID" value="KPL76056"/>
        <property type="gene ID" value="ADN00_11945"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="49"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="106"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="143"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="169"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="218"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="255"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="285"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="308"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="343"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="373"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="15"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL76056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="415" mass="44663" checksum="2FB0D84D11A08189" modified="2016-01-20" version="1">MFHRLRSLQKEYPAQYWLLFWGLLVSSAGISLIWPFLTIYLREKLDLPLTTVASLITLSSVATLVASLIAGPIMDRFGRKIIMVASLFLSAVTFVLMSFASTLPQFIILMLLRGAFTPLYSVAADAMVADLIEPDRRVEAYSLLRIVNNVGIALGPAVGGFITSSSYSTAFNLGGASLLIFALLVLFTIQETAPLRAAAAVESTLSGGGYLSIFKDRFFVSFCGAFTFSGMMSALVFVLLSVYVKENFGIPESQFGFLMTTNALVVVLFQFAVSRISNRHPPLRVLATGALVYAVGVGSIALGRGFFAFMLSIIVLTFGELLIAPTATTLVSQIAPAHLRGSYMGVFSLTVGVARGLGPIYGGVLNDKISPAAIWYGGLVVGLIAAVWYYRLYQIRRKQKQAVMVSAQTTSGGAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XJX4</accession>
    <name>A0A0P6XJX4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">50S ribosomal protein L14</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rplN</name>
        <name evidence="6" type="ORF">ADN00_12550</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 5">Binds to 23S rRNA. Forms part of two intersubunit bridges in the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit. Forms a cluster with proteins L3 and L19. In the 70S ribosome, L14 and L19 interact and together make contacts with the 16S rRNA in bridges B5 and B8.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the universal ribosomal protein uL14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063360.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12550"/>
    <dbReference type="EnsemblBacteria" id="KPL76157">
        <property type="protein sequence ID" value="KPL76157"/>
        <property type="gene ID" value="ADN00_12550"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3991"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.150.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01367">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036853">
        <property type="entry name" value="Ribosomal_L14_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000218">
        <property type="entry name" value="Ribosomal_L14P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005745">
        <property type="entry name" value="Ribosomal_L14P_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019972">
        <property type="entry name" value="Ribosomal_L14P_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11761">
        <property type="entry name" value="PTHR11761"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00238">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01374">
        <property type="entry name" value="Ribosomal_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50193">
        <property type="entry name" value="SSF50193"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01067">
        <property type="entry name" value="rplN_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00049">
        <property type="entry name" value="RIBOSOMAL_L14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL76157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="123" mass="13494" checksum="C7AACF2EEC848689" modified="2016-01-20" version="1">MIQQESRLKVADNTGAREVLVIHVMGGSKRRYGQIGDVVVATVKSAAPQGNVKKSDVVKAVIVRCSKEWRREDGSSIRFDDNACVILDTDGQNPKGTRIFGPVARELREKGFMKIVSLAPEVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKL4</accession>
    <name>A0A0P6XKL4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_01485</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80543">
        <property type="protein sequence ID" value="KPL80543"/>
        <property type="gene ID" value="ADN00_01485"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL80543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="86" mass="9878" checksum="5E7F2397AE9B79F5" modified="2016-01-20" version="1">MENQAQAADETRRIIFSRKNKNYTKLMFYVVNVKESGFWAGRGRRTGALARLIFEPSEAHSLPRPRVWARMVSCRSPVAAPLEQRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKT3</accession>
    <name>A0A0P6XKT3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF3854 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000003">
        <property type="protein sequence ID" value="KPL80848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061151.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000003.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80848">
        <property type="protein sequence ID" value="KPL80848"/>
        <property type="gene ID" value="ADN00_01275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024385">
        <property type="entry name" value="DUF3854"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12965">
        <property type="entry name" value="DUF3854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3854" evidence="1">
        <location>
            <begin position="119"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="885" mass="98362" checksum="DF039793FDCC0B4C" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XL62</accession>
    <name>A0A0P6XL62_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">M20_dimer domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_00235</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060947.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00235"/>
    <dbReference type="EnsemblBacteria" id="KPL81013">
        <property type="protein sequence ID" value="KPL81013"/>
        <property type="gene ID" value="ADN00_00235"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3441"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="1">
        <location>
            <begin position="196"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL81013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="456" mass="49801" checksum="30E3A71D571F8E3A" modified="2016-01-20" version="1">MYDQRSAAIQLAESQRHQTLADLKELVKIPSISTSQENYQDMLKAANWIAAYLSKIGMKNVQLLPTAGNPAVYGEAILDSSYPTVLIYGHYDVQPPDPLELWKSDPFDPVQDGDLLFGRGTSDMKGQILACIAAVDATLKTGGLKVNIKFIVEGEEEIGSPNLASAIRAHKDLLACDFVLNPDTGMVGENIPAITYGLRGLSYFEIKVTGPDHDLHSGLFGGIVHNPAQALAEVIAAMHDENGRVTLPGFYDDVRVLDEKERAELSRLPVSDDDFLRQTGAPALWGEKGFTPVERLGARPTLEVHGLYSGFIGEGQKTVLPSYAIAKISSRLVPNQDHEKVYQQLLAFLQEKMPPTVKWEAKKLSGGAPLLINPDQPATIAFAHALETAFQVKPVFKLEGGSVPVTTDLQEILGVQSILTGFGLPEDNIHSPNERLHLPTFYKGIDTIVHFLYNIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XLA6</accession>
    <name>A0A0P6XLA6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_10630</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062976.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77016">
        <property type="protein sequence ID" value="KPL77016"/>
        <property type="gene ID" value="ADN00_10630"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="233"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="279"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="309"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="342"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="395"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL77016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="422" mass="43779" checksum="10274798B9DB9CCF" modified="2016-01-20" version="1">MAQILAIAYKDFLRSTRSFFALGMMVAAPLLITGLIALAFGGLAASGSGDMTALRVLVLNADQPAEGQMDIGAMVLPFLQDEKMPAWLQAEAAADETAARQALDEGQAGALVLIPANFSDSIAAGQPAQITILQDPTLTIGPAVLENLLHIFTDGISGAQVGLTVITDQLASAGAQVDGSITQTALLAYTDWFKALQQNLNHSAEPQLQIVSPLGVEKDNAANTFQQVIAQTMAGMLIFFTFFTGASSAELLLKEQEEGTLARLFTTPGGRDAILAGKLLSGLLTILAQCAVLMAASSLLFGVKWGSPASVLLAVLATALAATGFGLLLLSGVRSMRQAGPVIGGVISATGMLGGLMTTAVPMPGLFTQLNLLVPQGWALRAWKLTLQGASFADVLFPALVLALIGAACYAAGSFIFRKRFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XLB2</accession>
    <name>A0A0P6XLB2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_00675</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061023.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL81077">
        <property type="protein sequence ID" value="KPL81077"/>
        <property type="gene ID" value="ADN00_00675"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3530"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="143"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="172"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL81077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="224" mass="24789" checksum="6E21426CF0A16950" modified="2016-01-20" version="1">MMKSQMTQFIHSATPRAAAIAGILFSIFFAITIILIRLSVPTDPTTVNDWTDATRSQVGLALRLMPFAGIAFLWFVGVVRDRLGEFEDKFFSTVTLGSGLLFLAMSFIAMANGAGMLAIYQATGGQAMSAELYALNRSVMNQIFNTYGLKMAGVFMFSISTLWLRTGVMPRLLCYFTYALVVFMLVTTSQNLWMVLIFPAWVLIVSILILVLTCAVKLREAKMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XLD8</accession>
    <name>A0A0P6XLD8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Energy-dependent translational throttle protein EttA</fullName>
            <ecNumber evidence="7">3.6.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Translational regulatory factor EttA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ettA</name>
        <name evidence="10" type="ORF">ADN00_10885</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">A translation factor that gates the progression of the 70S ribosomal initiation complex (IC, containing tRNA(fMet) in the P-site) into the translation elongation cycle by using a mechanism sensitive to the ATP/ADP ratio. Binds to the 70S ribosome E-site where it modulates the state of the translating ribosome during subunit translocation. ATP hydrolysis probably frees it from the ribosome, which can enter the elongation phase.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer. Probably contacts ribosomal proteins L1, L5, L33 and S7, the 16S and 23S rRNA and the P-site containing tRNA(fMet).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="7">Associates with ribosomes and polysomes.</text>
    </comment>
    <comment type="domain">
        <text evidence="7">The P-site tRNA interaction motif (PtIM domain) probably interacts with the P-site tRNA(fMet) as well as the 23S rRNA.</text>
    </comment>
    <comment type="domain">
        <text evidence="7">The arm domain is inserted in the first ABC transporter domain. Probably contacts ribosomal protein L1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the ABC transporter superfamily. ABCF family. Translational throttle EttA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="7"/>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063024.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10885"/>
    <dbReference type="EnsemblBacteria" id="KPL77053">
        <property type="protein sequence ID" value="KPL77053"/>
        <property type="gene ID" value="ADN00_10885"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2656"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045900">
        <property type="term" value="P:negative regulation of translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00847">
        <property type="entry name" value="EttA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022374">
        <property type="entry name" value="EttA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43858">
        <property type="entry name" value="PTHR43858"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03719">
        <property type="entry name" value="ABC_ABC_ChvD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="6 7" id="KW-0810">Translation regulation</keyword>
    <keyword evidence="2 7" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="10"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="329"/>
            <end position="555"/>
        </location>
    </feature>
    <feature type="region of interest" description="PtIM" evidence="7">
        <location>
            <begin position="247"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <begin position="42"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7 8">
        <location>
            <begin position="361"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL77053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="561" mass="63520" checksum="4E1EFBFC03D2A4BC" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XMB6</accession>
    <name>A0A0P6XMB6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_18625</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18625"/>
    <dbReference type="EnsemblBacteria" id="KPL70064">
        <property type="protein sequence ID" value="KPL70064"/>
        <property type="gene ID" value="ADN00_18625"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.90.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035328">
        <property type="entry name" value="DUF3048_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021416">
        <property type="entry name" value="DUF3048_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023158">
        <property type="entry name" value="YerB-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11258">
        <property type="entry name" value="DUF3048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17479">
        <property type="entry name" value="DUF3048_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159774">
        <property type="entry name" value="SSF159774"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3048" evidence="1">
        <location>
            <begin position="1"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3048_C" evidence="2">
        <location>
            <begin position="162"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL70064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="300" mass="34341" checksum="1F12552171E233B4" modified="2016-01-20" version="1">MIKVSNFPAGPGRPHAGLSYADLVFEYYIGEYMNRFLAVFYGQDTPKAWPLRSGRLIDPQLVNMYHGVLVYGSADERVDEKILTELGMRAISNLNAPCPPICGELTHSATGVYVDSASVTEFTSRHGVENTRPDLRGMLFSETPPQTSQYGASVLVQYIRWNRGEWRYDDQSGKYLRWIESWDQGDEYPLIPLVDQLTGEQLAFSNVVILFANYIEYNYRLHDVEIWDNTEMQRAVFFRDGLMVDGFWRAPLRDHPIQFFNQQGLPMQLKPGNTWVVVAGKSSEFNQSSPGQWQCLFDIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XME5</accession>
    <name>A0A0P6XME5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_00275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060953.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL81019">
        <property type="protein sequence ID" value="KPL81019"/>
        <property type="gene ID" value="ADN00_00275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL81019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="121" mass="13477" checksum="DDB53774479B185B" modified="2016-01-20" version="1">MGKYDNYSSQNRPARGTLTHPIWRGVGFGLAILTPVIAYSAALILIDANAQNGWVAIPRDLIAPTGDPLLYVKIILTLVMVFLLYLIFSFITFILYGIFGPPRYGPKDVPPTSYRGGKYRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XMF1</accession>
    <name>A0A0P6XMF1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_18840</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064586.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70101">
        <property type="protein sequence ID" value="KPL70101"/>
        <property type="gene ID" value="ADN00_18840"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="184" mass="19708" checksum="C7F339CFC793B20A" modified="2016-01-20" version="1">MTIVQGSLSSIAKQNQISIAESFINADCICIVDTSGSMEDKDSRGGLSRYEVACQELSQLQKNLPGKIAVISFSSAVQFCPNGVPVFLGATTDLAKALNFVKVADVPEMRFIIISDGQPDSEEESLRVAATFKNRIDVIYVGPEDRPQGREFLQKLAAVTGGKSVTVDRAKELQAGIMGLLHAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XMZ2</accession>
    <name>A0A0P6XMZ2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_07900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77803.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062447.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77803">
        <property type="protein sequence ID" value="KPL77803"/>
        <property type="gene ID" value="ADN00_07900"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133137" evidence="1">
        <location>
            <begin position="21"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77803.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="295" mass="32848" checksum="5650CAC1491A1628" modified="2016-01-20" version="1">MKSRISILIVSCLLILLMLACGTSNELTNPPAGSPDSNQSASETAAALAKQSAQIEATNVAIQATNQAILDAQATLLAPTETPEDPFAGEDYQGEEIPSDPEMVEITTEAREKLQPLFAEGLLSDDDLETAEFYRLDDFDESWAQINWYQWWNTGYQPQNFIIRVDSAWETASNTANWFSSGCDFVYSESDESNHYMTFLALDGNVHTFRNLKNKFTEMKGGYYGKVGTPNGDAELLLMVKDQYVTFFVNGRKVVRFQDPNLTAGNLGLTLNSGTIKDYGFRCMMTDIDLWILAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XPZ5</accession>
    <name>A0A0P6XPZ5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_16840</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064217.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL71372">
        <property type="protein sequence ID" value="KPL71372"/>
        <property type="gene ID" value="ADN00_16840"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL71372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="133" mass="14867" checksum="FC414036DDD2F752" modified="2016-01-20" version="1">MSLNPRGIIPGDQGWLKEFVLRVKLFMRLMADKRVNPFLKLIPALSLVYLVVPFDFAPIIPLDDAAILGLGMYLFIEFCPPEVVEEHMSQLRRLPPSAVQPPAESNVIEATFNEAPAAQLQPEKQAPQATDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQ00</accession>
    <name>A0A0P6XQ00_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_16900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064227.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL71381">
        <property type="protein sequence ID" value="KPL71381"/>
        <property type="gene ID" value="ADN00_16900"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="48"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL71381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="77" mass="8895" checksum="50D881FAE296A14A" modified="2016-01-20" version="1">MLDDLRNTATSNAEEEISSYEEDRKRAQKRKRSVPETRIFGMTAAQRFVLILLVLLMTCVLGIFFLVFTGSVYLPFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQB6</accession>
    <name>A0A0P6XQB6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">LTD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_03335</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061545.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03335"/>
    <dbReference type="EnsemblBacteria" id="KPL78945">
        <property type="protein sequence ID" value="KPL78945"/>
        <property type="gene ID" value="ADN00_03335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001322">
        <property type="entry name" value="Lamin_tail_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036415">
        <property type="entry name" value="Lamin_tail_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00932">
        <property type="entry name" value="LTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74853">
        <property type="entry name" value="SSF74853"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="LTD" evidence="2">
        <location>
            <begin position="68"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="170" mass="18797" checksum="AE43C54C9EF170DB" modified="2016-01-20" version="1">MKTKKSIWPYILVNILVSAATTLLVLWLWDRAHQIQPPPQAVQPAAAQTSAPAAPTLAPTPALPPLNQPVIQIKNVFGEGDLNSEVVVLSRLGEGELWLTGWKLQNESGDSFIFPDLQLHKDAEIQVYSRAGVNSALALYWNRSEPAWKTGDLVTMIDYQGNIRASYRIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQF1</accession>
    <name>A0A0P6XQF1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Pyridoxal-5-phosphate-dependent protein subunit beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_03620</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061602.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03620"/>
    <dbReference type="EnsemblBacteria" id="KPL78991">
        <property type="protein sequence ID" value="KPL78991"/>
        <property type="gene ID" value="ADN00_03620"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.76"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="489" mass="55204" checksum="E2799284D4243AA6" modified="2016-01-20" version="1">MAKIDLTVFEDRRKKAVRRAKERNIIIPTFAQMKNPDLIPDTIKAELANIGLWDVTARNLFRITWKNEPKSFGGQFGGVNYLELPSSLTGVPARIVVLVGKWFPTGAHKVGATFGCLVPRLVTGQFDPETQKAVWPSTGNYCRGGAYDSTLLACESIAILPEGMSRERFDWLKTVAGEIIATPGTESNVKEIFDKCWELRRSGEDLMIFNQFEEFGNYLWHYEVTGHAMEEVLKQVMGPKDNYAGMALTTGSAGTIGCGDFIKQLYPTSKIAASEALQCPTLLENGFGAHRIEGIGDKHVPWIHNVKNTDMVMAIDDAAVVNISRLFNEPAGRAYLVKKGVPEALVPQLDLLGFSGIANVLSSIKMAKYYEWGENDVVLTVLTDSMELYGSRLKEMHEEYGQYTEADAAEHYARYLHGERIDNLLELTYADRRRVHNLKYYTWVEQQGKTYEEILDQWYAPDYWTEFQSQTEEIDELINEFNAMTGLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQT5</accession>
    <name>A0A0P6XQT5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_04770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061812.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79165">
        <property type="protein sequence ID" value="KPL79165"/>
        <property type="gene ID" value="ADN00_04770"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021309">
        <property type="entry name" value="DUF2892"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11127">
        <property type="entry name" value="DUF2892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="68" mass="7420" checksum="605253DF8BA90ACC" modified="2016-01-20" version="1">MKNMVNEASWDRILRVVVGAVLLWMGWGGAVSGGLAWVFKVVGFIPLLTGLVGFCPAYALLKIRTNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XRI1</accession>
    <name>A0A0P6XRI1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phosphoribose diphosphate:decaprenyl-phosphate phosphoribosyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_08310</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062520.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08310"/>
    <dbReference type="EnsemblBacteria" id="KPL77870">
        <property type="protein sequence ID" value="KPL77870"/>
        <property type="gene ID" value="ADN00_08310"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.664"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016765">
        <property type="term" value="F:transferase activity, transferring alkyl or aryl (other than methyl) groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039653">
        <property type="entry name" value="Prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044878">
        <property type="entry name" value="UbiA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11048">
        <property type="entry name" value="PTHR11048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="107"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="132"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="157"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="195"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="234"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="272"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL77870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="291" mass="32536" checksum="72DB79C7496BBB23" modified="2016-01-20" version="1">MLMGLIKSMRPRQWTKNVFVLAALVFDRQLNNPLAVSRTLAGLIIFCFISSAVYLINDVKDIEADRAHPRKKNRPIASGQLPVRVAVISAVIIIMFSLAASIVLSPLFAMVVVLYLIINVLYSFWLKHVPLIDVLLISAGFVLRVSAGVTLIVVERFSPWLFAVTTLFTLYLGFGKRRAELATLSKDQAQSHRRVLDGYTIPLLDQLITIVSSTTIMAYSLYTFSAVNLPENHTMMLTIPFVIYGIFRYLYLIQVKGAGGAPEDMVLSDRPLQITVALYCLAVLLIFYIFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XRJ2</accession>
    <name>A0A0P6XRJ2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_08360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062530.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77879">
        <property type="protein sequence ID" value="KPL77879"/>
        <property type="gene ID" value="ADN00_08360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="202"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="277"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="302"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="330"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="372"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="399"/>
            <end position="417"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="569" mass="61963" checksum="AD7A4759D55E8179" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XRL0</accession>
    <name>A0A0P6XRL0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_02635</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000012">
        <property type="protein sequence ID" value="KPL79430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79430">
        <property type="protein sequence ID" value="KPL79430"/>
        <property type="gene ID" value="ADN00_02635"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="79" mass="8752" checksum="0367F5ABCA0DC776" modified="2016-01-20" version="1">MHSKRGRPKLDCKVHQIRFTLSLREGEDDDLIFFFSDIPERRRAAALKAALRAGGISLKAGSVPITDDLDLTIQGLVFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XRM3</accession>
    <name>A0A0P6XRM3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_08545</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062565.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08545"/>
    <dbReference type="EnsemblBacteria" id="KPL77907">
        <property type="protein sequence ID" value="KPL77907"/>
        <property type="gene ID" value="ADN00_08545"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00756">
        <property type="entry name" value="MoaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036563">
        <property type="entry name" value="MoaE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003448">
        <property type="entry name" value="Mopterin_biosynth_MoaE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003749">
        <property type="entry name" value="ThiS/MoaD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02391">
        <property type="entry name" value="MoaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02597">
        <property type="entry name" value="ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="SSF54285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54690">
        <property type="entry name" value="SSF54690"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL77907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="233" mass="25116" checksum="153306FF1CA005EB" modified="2016-01-20" version="1">MKVSILFFASIKEKAGCADTVMDVPAGTTIQGLKERVEAAFPGLKNVMGNSLTSMNRSFALNEDLITDGAEIAFFPPVSGGSGARRVIQLTREPLALEDLTMSITTPATGAVCAFIGVIRGITTKGHGHITTALEFEAYEPMALEKMNQIADEMESRWPDLFGIAMVQRIGLQSPKSPTVLIACSAAHRDTGVFEAAKYGIDRLKEIVPIWKKEIGPDGEVWVEGDYLPGRGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XSC1</accession>
    <name>A0A0P6XSC1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_12760</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063405.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000027.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12760"/>
    <dbReference type="EnsemblBacteria" id="KPL75512">
        <property type="protein sequence ID" value="KPL75512"/>
        <property type="gene ID" value="ADN00_12760"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004371">
        <property type="term" value="F:glycerone kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006071">
        <property type="term" value="P:glycerol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036117">
        <property type="entry name" value="DhaL_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101473">
        <property type="entry name" value="SSF101473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL75512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="217" mass="22738" checksum="F80167049CF35C2C" modified="2016-01-20" version="1">MASNEIDLAQVFQAVTQTLASNQGALNQADDYNHNHGDNMVEIFNLVTQAVQKKGKKPAADQLAYASKMLSKQAQSGSAQAYAQGLSRAAQQFKGRDLQPENALELIELLMGNPAASQAQAQPAVDPNAELLNSLLGSLSGETQSGQQGQEGLDMADLLAGGLAFLQSRQRGESTMEALLDAVMAGSQMGQSAHRAQSGKLVSGTLLQMLAQGLGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XU67</accession>
    <name>A0A0P6XU67_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_05325</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061937.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78675">
        <property type="protein sequence ID" value="KPL78675"/>
        <property type="gene ID" value="ADN00_05325"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="117" mass="13447" checksum="F4C801379FD608CC" modified="2016-01-20" version="1">MTQNSSKHILVIAPASRKRENLLAMFALLNPDTSIQIADDWRTARKYLVFSSPDVFLVDYRNPDDELNQEISSLLETHPCQKIVLLKNRICQRNPFFSPAIQEVIYDDISTNVLTLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUC7</accession>
    <name>A0A0P6XUC7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ABC transmembrane type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_05775</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062019.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78748">
        <property type="protein sequence ID" value="KPL78748"/>
        <property type="gene ID" value="ADN00_05775"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="16"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="80"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="115"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="156"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="241"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="274"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="78"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL78748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="300" mass="33665" checksum="9E75A9FB4B121DF9" modified="2016-01-20" version="1">MALLKHISRRQREERLLVIFLVAPAALIMAGVTVYPLVRSLWISLLKWDLTKPQLGHPFIGFENYLHVLKDPIFWQCARVTALFVVGAVTLEIVLGLLLALLLNKDFVGKNFVRMLALLPWAIPPVVNGIMWKWILNPSYGALNGMLYSLKIIDQYVVWLGSPTLALLMVILADVWKETPFIMLLFLAALQTIPQDLYEAAEVDGANALQKLFQITIPMIRPTLFVALSLRTIWALKSFDLIYTLTAGGPSNGTNVIGFYTYMKSFVSLDLGRGAAAAYIMTIVVMLVVVLYQRALTREK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUI4</accession>
    <name>A0A0P6XUI4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_06215</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062098.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06215"/>
    <dbReference type="EnsemblBacteria" id="KPL78812">
        <property type="protein sequence ID" value="KPL78812"/>
        <property type="gene ID" value="ADN00_06215"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1744"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="148"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="195"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="231"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="267"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL78812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="296" mass="31495" checksum="A3024B1FAB455E05" modified="2016-01-20" version="1">MKILVGLINGMITGATPILLAALGGTLTYYAGIFNIAMEGMMLGGAFFAVLGSYYFQSWGMGIVAAILGSLLMALIFILFSVVLKTDEFVTGIGLNLFALGATTYLLRQIFQVKGAFSGPGIVSIPSVDIPLLKDIPFLGEILSGQNLVVYLALLATVVISYLVFKTPFGLRLRAAGYNAACLDTSGVRTSRIRVWSLLLCGVLCGLAGAYLSLGYVTLFSENMSAGRGWISLAAIILVNGSPWGIAIISLLFGFSDGFGLLLQQYIPSQFASMAPYVATLVALYVYSVREKKKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XV65</accession>
    <name>A0A0P6XV65_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">ADN00_04490</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Component of the dihydroxyacetone kinase complex, which is responsible for the phosphoenolpyruvate (PEP)-dependent phosphorylation of dihydroxyacetone. DhaM serves as the phosphoryl donor. Is phosphorylated by phosphoenolpyruvate in an EI- and HPr-dependent reaction, and a phosphorelay system on histidine residues finally leads to phosphoryl transfer to DhaL and dihydroxyacetone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-histidyl-[protein] + phosphoenolpyruvate = N(pros)-phospho-L-histidyl-[protein] + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:23880"/>
            <dbReference type="Rhea" id="RHEA-COMP:9745"/>
            <dbReference type="Rhea" id="RHEA-COMP:9746"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:29979"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:64837"/>
            <dbReference type="EC" id="2.7.3.9"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>dihydroxyacetone + phosphoenolpyruvate = dihydroxyacetone phosphate + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:18381"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:16016"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="2.7.1.121"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the PEP-utilizing enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061759.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04490"/>
    <dbReference type="EnsemblBacteria" id="KPL79123">
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        <property type="gene ID" value="ADN00_04490"/>
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    <dbReference type="PATRIC" id="fig|1134406.4.peg.255"/>
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    </dbReference>
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        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="project" value="InterPro"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047324">
        <property type="term" value="F:phosphoenolpyruvate-glycerone phosphotransferase activity"/>
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        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008965">
        <property type="term" value="F:phosphoenolpyruvate-protein phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="PTS_EIIA_man-typ_sf"/>
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        <property type="entry name" value="PtsI_HPr-bd_sf"/>
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        <property type="match status" value="1"/>
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    <dbReference type="PRINTS" id="PR00107">
        <property type="entry name" value="PHOSPHOCPHPR"/>
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    <keyword evidence="11" id="KW-0598">Phosphotransferase system</keyword>
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    <keyword evidence="9" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
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            <end position="134"/>
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        </source>
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        <source>
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        </source>
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        <source>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="841" mass="90707" checksum="29851F87DCB87D10" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XVD5</accession>
    <name>A0A0P6XVD5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="KPL80582">
        <property type="protein sequence ID" value="KPL80582"/>
        <property type="gene ID" value="ADN00_01700"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="match status" value="1"/>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="125" mass="13915" checksum="FE2BEC0C08C7D49D" modified="2016-01-20" version="1">MMNFAIMLLAREQGAAAFGLQDAQVQQYWSAPWHLPLAGAVERITTIVLHVLLTSLVWLAVRTRNYLWFGTALLWHALTDSLVVLLASVEVSIWTIEAVLAGIMIINLVGLFLLQRRYGALPAET</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XVN6</accession>
    <name>A0A0P6XVN6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_02715</name>
    </gene>
    <organism evidence="4 5">
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        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000013">
        <property type="protein sequence ID" value="KPL79369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_LGCL01000013.1"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="KPL79369">
        <property type="protein sequence ID" value="KPL79369"/>
        <property type="gene ID" value="ADN00_02715"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2176"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="match status" value="1"/>
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        <property type="match status" value="1"/>
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        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
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        <property type="entry name" value="HisKA_7TM"/>
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        <property type="entry name" value="Nucleotide_cyclase"/>
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    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
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        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="PAS_4"/>
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    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HisKA_7TM"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF55785"/>
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    </dbReference>
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        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="204"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="2">
        <location>
            <begin position="298"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="3">
        <location>
            <begin position="381"/>
            <end position="479"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL79369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="479" mass="54179" checksum="236ABF8EC50E3896" modified="2016-01-20" version="1">MVYTPGLWLFLLAALITMGVIGFSWRYRQTDTGKAFLALMVCGLVWVVFFCFETASPALEGKLFWAKIQFLGITFLPTAWVFLVLALTGQKAARGVKTALLLLPALTNLVIWTNPLHHWFYGTPFISSTLAPFPVLVQDYQFWFYYVHAPLNYLILLAALFLLVKAMVRMEGMYQTQAQLLLVSILLPAITDMLYVLGYSPVRYYNYTTAVFSLSGVILAWTLFRYQFLDLLPLARDVMIGQMSDLVMILDHKTRISEANPAARDVFHLPKEFVGKQPTEIGSRDLLEVAGLLEQGVAHKDVQFEAQPGRTFDLRIQPVMKSGGLVIGWVITARDISERVEFLNRLQALATRDDLTGIYNRRHFLELCQREMYRVQRLKDYHVAVMMIDLDHFKLVNDAHGHAIGDRALAAFANAVQAELRVMDIFGRLGGEEFALLLVDVDESAARAAAERLGLSLKNLETAPKISCKSNKNEKTKNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XW55</accession>
    <name>A0A0P6XW55_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5 6">50S ribosomal protein L19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplS</name>
        <name evidence="7" type="ORF">ADN00_14530</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">This protein is located at the 30S-50S ribosomal subunit interface and may play a role in the structure and function of the aminoacyl-tRNA binding site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the bacterial ribosomal protein bL19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000035">
        <property type="protein sequence ID" value="KPL73557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063755.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000035.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14530"/>
    <dbReference type="EnsemblBacteria" id="KPL73557">
        <property type="protein sequence ID" value="KPL73557"/>
        <property type="gene ID" value="ADN00_14530"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2072"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00402">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038657">
        <property type="entry name" value="L19_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001857">
        <property type="entry name" value="Ribosomal_L19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018257">
        <property type="entry name" value="Ribosomal_L19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15680">
        <property type="entry name" value="PTHR15680"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01245">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002191">
        <property type="entry name" value="Ribosomal_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00061">
        <property type="entry name" value="RIBOSOMALL19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01024">
        <property type="entry name" value="rplS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01015">
        <property type="entry name" value="RIBOSOMAL_L19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 7" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00402"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL73557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="115" mass="13086" checksum="50C14F5A6D51DFB6" modified="2016-01-20" version="1">MSDLIKAIEPAVNPNVPKLRAGDVVNVHVKIKEGNRERIQEFKGTVLYTHGGDGATATFTVRRLASNGVGVERTFLYRSPRIDKVEVERHSVVRRARLFYLRNLTGKRARLKQKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XXE0</accession>
    <name>A0A0P6XXE0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PPDK_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01565</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061204.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01565"/>
    <dbReference type="EnsemblBacteria" id="KPL80558">
        <property type="protein sequence ID" value="KPL80558"/>
        <property type="gene ID" value="ADN00_01565"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1070"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002192">
        <property type="entry name" value="PPDK_AMP/ATP-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01326">
        <property type="entry name" value="PPDK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPDK_N" evidence="1">
        <location>
            <begin position="200"/>
            <end position="574"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="778" mass="88525" checksum="5F1B52BB004CEC43" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XXE5</accession>
    <name>A0A0P6XXE5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Deoxynucleoside kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_01610</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061213.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01610"/>
    <dbReference type="EnsemblBacteria" id="KPL80567">
        <property type="protein sequence ID" value="KPL80567"/>
        <property type="gene ID" value="ADN00_01610"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1082"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019136">
        <property type="term" value="F:deoxynucleoside kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01673">
        <property type="entry name" value="dNK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002624">
        <property type="entry name" value="DCK/DGK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031314">
        <property type="entry name" value="DNK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01712">
        <property type="entry name" value="dNK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000705">
        <property type="entry name" value="DNK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="dNK" evidence="4">
        <location>
            <begin position="5"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="9"/>
            <end position="17"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="138"/>
            <end position="142"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000705-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000705-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000705-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL80567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="220" mass="25951" checksum="09721897E97E68CF" modified="2016-01-20" version="1">MKKFIAIAGNIGVGKSTLARLLSQRLEWQPFYEPVTENPYLSDFYKDMRAWGFHSQIFFLSHRLQIHLDLVNYPGSVIQDRSIYEDAEIFAQNLFLQGHLSERDWKTYWTLYQSMTEFLPPPDLVIYLRASEKTLLERISHRNRDYEKKIQPEYLKELNQLYENWIHGFTLCPVLTVPADDLDYVAHSRHLDLILTKVQEKLIGKEVVVFNADEVKANKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XXG1</accession>
    <name>A0A0P6XXG1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B</fullName>
            <shortName evidence="10">Asp/Glu-ADT subunit B</shortName>
            <ecNumber evidence="10">6.3.5.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">gatB</name>
        <name evidence="13" type="ORF">ADN00_01775</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP + H2O + L-aspartyl-tRNA(Asn) + L-glutamine = ADP + 2 H(+) + L-asparaginyl-tRNA(Asn) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14513"/>
            <dbReference type="Rhea" id="RHEA-COMP:9674"/>
            <dbReference type="Rhea" id="RHEA-COMP:9677"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78515"/>
            <dbReference type="ChEBI" id="CHEBI:78516"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 10">
            <text>ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln) = ADP + H(+) + L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17521"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="Rhea" id="RHEA-COMP:9684"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4 10">Heterotrimer of A, B and C subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the GatB/GatE family. GatB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.-" evidence="10"/>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80595.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061242.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01775"/>
    <dbReference type="EnsemblBacteria" id="KPL80595">
        <property type="protein sequence ID" value="KPL80595"/>
        <property type="gene ID" value="ADN00_01775"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1118"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050566">
        <property type="term" value="F:asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050567">
        <property type="term" value="F:glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00121">
        <property type="entry name" value="GatB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004413">
        <property type="entry name" value="Apn/Gln-ADT_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017959">
        <property type="entry name" value="Asn/Gln-tRNA_amidoTrfase_suB/E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006075">
        <property type="entry name" value="Asn/Gln-tRNA_Trfase_suB/E_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018027">
        <property type="entry name" value="Asn/Gln_amidotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003789">
        <property type="entry name" value="Asn/Gln_tRNA_amidoTrase-B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042114">
        <property type="entry name" value="GatB_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023168">
        <property type="entry name" value="GatB_Yqey_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017958">
        <property type="entry name" value="Gln-tRNA_amidoTrfase_suB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11659">
        <property type="entry name" value="PTHR11659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02934">
        <property type="entry name" value="GatB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02637">
        <property type="entry name" value="GatB_Yqey"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00845">
        <property type="entry name" value="GatB_Yqey"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89095">
        <property type="entry name" value="SSF89095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00133">
        <property type="entry name" value="gatB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01234">
        <property type="entry name" value="GATB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GatB_Yqey" evidence="12">
        <location>
            <begin position="331"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="467"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="468"/>
            <end position="487"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KPL80595.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="487" mass="54717" checksum="73A09E0B2508E10A" modified="2016-01-20" version="1">MKYEAVIGLEVHAELATNSKMFCSCPVVDPTRAAPNTAVCPVCCGLPGVLPVVNEKAVEYAVRVGLALECEIAPMSLFARKNYFYPDLPKGYQISQYEYPICKDGRLTIYTSQGEKVIRITRAHLEEDTGKLTHVEQEDGAYSLIDLNRAGVPLLEIVTEPDLRSVEEVRAYAQELRAILRYLGVNTGDMEKGVIRFEANVSVRPEGSQELNTRVEIKNLNSFRALERATAYQIEQQIAMMERGEPVRLETLGWDETNEVTFSQRSKEEAHDYRYFPEPDLPPLVVDAAWIEAIASTLPELPRAKAHRFIRSYGVAEAIAEQLISEQAVANYFEEVLRANPDLDPQTVGVWITGELFGWLNQSGETIQTIKVTPAGLAALLQDVKNARVNANTAKSVLVEMLRSGRQADDIIRNQGLEQISDAQTIARLVRQTLETNPKELESYFNGKETLAQWFFGQVMRSARGKANPQVVREELEKQLQERKSQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XYE3</accession>
    <name>A0A0P6XYE3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MFS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_07610</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062380.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07610"/>
    <dbReference type="EnsemblBacteria" id="KPL78310">
        <property type="protein sequence ID" value="KPL78310"/>
        <property type="gene ID" value="ADN00_07610"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3350"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="43"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="80"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="143"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="169"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="230"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="261"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="289"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="326"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="366"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="395"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="10"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL78310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="420" mass="46177" checksum="C55F8430B3C5371C" modified="2016-01-20" version="1">MEEKRFSYPKTFLLGFGFFGVSIIWAIYNAFVPLILDRQFGLSAFWIAIFMVLDNLAAVLIQPWVGAWSDRLRTPLGRRLPFILIGAPVAAIAFGLMPLSSSLVLFVLTATTVLVSMAFWRTPVIALMPDITPSAQRSQANGIINFMGGLASVISFAVGSQLYAKNPNYAFWLGSALVTLSAILVLVFIREPKEYSTRDDQKAERPDVWKSITSVFAEEERSAARMLTAILFWFLSWYAIETFFTLYAVKHLGLGEADAAFQLTYVSLIFLVFAIPSGYIAAKFGRKRTIITGIVMMIVSLGLMYVLPPSITVGARIASVTKTAGIYPVSFILMLAGFAWSLININSLPMVVDMTTDENLGAYTGLYYFSSQTAAVVGPLAFGAAVQFSGNNYNLMMLISPIFLLFALAMMVGVRRGEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y0B6</accession>
    <name>A0A0P6Y0B6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05905</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062043.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05905"/>
    <dbReference type="EnsemblBacteria" id="KPL78767">
        <property type="protein sequence ID" value="KPL78767"/>
        <property type="gene ID" value="ADN00_05905"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016861">
        <property type="term" value="F:intramolecular oxidoreductase activity, interconverting aldoses and ketoses"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005996">
        <property type="term" value="P:monosaccharide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009015">
        <property type="entry name" value="Fucose_isomerase_N/cen_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53743">
        <property type="entry name" value="SSF53743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="476" mass="52748" checksum="5C76333EF3F9B3CB" modified="2016-01-20" version="1">MKNMRKLRIGLAGVMTTPFRGDKEGNFQEDWQALSKLANSLGFELKTIKEGIYNQDQANNAARELQNWGADFILLQNSSFAAGQFIYPFADTKIRLGLWAVTEGKPTSEGGLPLNSFTGLNLYNSLLKTFRTDYNLPVKWFFGRPGQPLFDQRLRVTVQALHAVINLQNSRIGLIGGVASGFDNLIVDPRNLKRKIGAEVIILDFDTLLKEAQAIKDQTAIQTTAEGFIRVNTQFDKRMVPQLEKLSRLEIAYQHAADNFGLDAVAVSCWPRYQSDYGVAVCSLMGQLNSTGLIAACEGDVPSAAGMLALHYMSSGDVVTLMDLVTVDENDDSVLLWHCGPTSPILADNKGTRMQSLWLFDQDQKPPTGLHNDLVLKPGEATVMGFTPDFEQLLVLDGEIDNQKPSYVGSRGWYRNLRVGAEPASVPDVVQTLMNSGYQHHYPLAYGNLMPAAMEMAGWLGIKPIKKQTYTDYLIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y0F0</accession>
    <name>A0A0P6Y0F0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TGc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_06095</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062079.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06095"/>
    <dbReference type="EnsemblBacteria" id="KPL78795">
        <property type="protein sequence ID" value="KPL78795"/>
        <property type="gene ID" value="ADN00_06095"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1698"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002931">
        <property type="entry name" value="Transglutaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01841">
        <property type="entry name" value="Transglut_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00460">
        <property type="entry name" value="TGc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="183"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="222"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="612"/>
            <end position="631"/>
        </location>
    </feature>
    <feature type="domain" description="TGc" evidence="2">
        <location>
            <begin position="505"/>
            <end position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="742" mass="82753" checksum="6697CB5C7F84D71E" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y293</accession>
    <name>A0A0P6Y293_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">G5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_03990</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061670.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03990"/>
    <dbReference type="EnsemblBacteria" id="KPL79051">
        <property type="protein sequence ID" value="KPL79051"/>
        <property type="gene ID" value="ADN00_03990"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007137">
        <property type="entry name" value="DUF348"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011098">
        <property type="entry name" value="G5_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03990">
        <property type="entry name" value="DUF348"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07501">
        <property type="entry name" value="G5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01208">
        <property type="entry name" value="G5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51109">
        <property type="entry name" value="G5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="G5" evidence="2">
        <location>
            <begin position="256"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="457" mass="49880" checksum="7B4468C7F8C2EA59" modified="2016-01-20" version="1">MAYSITALLCLGGLFLLFTGIRRPAEIFIENQRFIVQTRALTVGQALRDGGVTLAPQDRVNPPVGALLAWQPVIRVQKASQVNLFTGDSLTAALHAVERIPANLLGAQGIRLYPHDRLLWNGEPIDPLRPLPLAQVYNLQLIPAQKAAITTPTGQTVTAYTAAQTVAQALADAGISISPALDVQPPLDAPLPSPPQIRIQQGRELRVQVADRELLTFTHAQTVGQALAQAGVALQSLDYSQPPESASLPADGRVRVVRVREEILLEQQPIPFDNELVPDPDLELDQRRVVEPGQYGIEVSRVSVRYEDGQEVSRQTEETWTASQPVTQKMGYGTKIEIRTLDTLSGPIEYWRAVTVYATSYSPCRSGTNTCYNGTASGLPVQRGVIGVTRAWYNWMVGQGVYIPGYGPAVVADVGGGVPGTHWIDLGFTDDDYEAWHSNVTLYFLTPVPENIPWILP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y2G5</accession>
    <name>A0A0P6Y2G5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_04495</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061760.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79124">
        <property type="protein sequence ID" value="KPL79124"/>
        <property type="gene ID" value="ADN00_04495"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="35"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="90" mass="10464" checksum="396F738E5DB2F927" modified="2016-01-20" version="1">MSNSKKNKSQAGSRKQEESLEKQLKIGEPWIERSAGMKWLLILSLITAGYITWQLEPSLGFWEALLWGLGFGGSLWLIFYGMQWFRKLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y352</accession>
    <name>A0A0P6Y352_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_11925</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063242.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11925"/>
    <dbReference type="EnsemblBacteria" id="KPL76053">
        <property type="protein sequence ID" value="KPL76053"/>
        <property type="gene ID" value="ADN00_11925"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3861"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009247">
        <property type="term" value="P:glycolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009695">
        <property type="entry name" value="Diacylglyc_glucosyltr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007235">
        <property type="entry name" value="Glyco_trans_28_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04101">
        <property type="entry name" value="Glyco_tran_28_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06925">
        <property type="entry name" value="MGDG_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MGDG_synth" evidence="6">
        <location>
            <begin position="37"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_tran_28_C" evidence="5">
        <location>
            <begin position="260"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL76053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="430" mass="48400" checksum="FF344CF7FF72F90D" modified="2016-01-20" version="1">MNRLSSNDYLHQLRADNTLNNRPRRILLLTANAGFGHRSAAIALEEALKEIYGSQAQVFMVNPLDDRRAPLLLRESQSDYDKIVRNMPELYRLGYEASDATIPTVMVESALTVLLYELMVDIVDQIKPDAIISTYPLYQAPLAAYFTISRHYIPCMTVVTDLATVHRIWFNEHMDHLFVPTETVKKLAVEHGISEDSITLTGIPVHPRISRETRSKDQIREELGWQKEITTLLAVGSKRVEGLMDALTVVNHFGYPLQLAVVAGKDEETYQALKAVDWHIPVHLYNFVENMPMLMHASDAIISKAGGLITTESLAAGLPMIFIDLIPGQETGNADYVVSNNAGDITRKPLEVLSALKHLTMDDMRLLKERSANARRLGKPFAAYEIARLAYQAAERGPITRERKILQIRPKLIDLLTQNHITIKKDADTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y371</accession>
    <name>A0A0P6Y371_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_12045</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063264.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12045"/>
    <dbReference type="EnsemblBacteria" id="KPL76071">
        <property type="protein sequence ID" value="KPL76071"/>
        <property type="gene ID" value="ADN00_12045"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003329">
        <property type="entry name" value="Cytidylyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02348">
        <property type="entry name" value="CTP_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="257" mass="29240" checksum="1CD970D8D99ECA5D" modified="2016-01-20" version="1">MKIVAIIQARMSSSRLPGKVLKEISGKPMLQHVVERVRRSQIVDEVLVATTIEASDDPLADYCQQNGIAVFRGPLQDVLDRFYQAAKSCGADVVVRITADCPVIDPQLIDDLVRQFLAAKVDFAANRLPPPWKRTYPIGLDTEVCTFSALERAWNEADQPYQREHVMPYLYEQEGRFEVLVVNYASDLGSQRWTVDTPEDLEFIQRVFESFGGRNDFGWMDVWKLVVEHPELSEINAGVRHKVFNESEQKADQARQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y4M6</accession>
    <name>A0A0P6Y4M6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_01985</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000007">
        <property type="protein sequence ID" value="KPL80065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061288.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000007.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01985"/>
    <dbReference type="EnsemblBacteria" id="KPL80065">
        <property type="protein sequence ID" value="KPL80065"/>
        <property type="gene ID" value="ADN00_01985"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025202">
        <property type="entry name" value="PLD-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001736">
        <property type="entry name" value="PLipase_D/transphosphatidylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13091">
        <property type="entry name" value="PLDc_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00155">
        <property type="entry name" value="PLDc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50035">
        <property type="entry name" value="PLD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133365" evidence="1">
        <location>
            <begin position="24"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="2">
        <location>
            <begin position="132"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="PLD phosphodiesterase" evidence="2">
        <location>
            <begin position="294"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL80065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="355" mass="38585" checksum="5A71D854EDBBCD30" modified="2016-01-20" version="1">MKQPTRPIFLTILLLFAAALTLAACRTSVPLPAPTFTALPPSVDLYFTHACTPAQQPDAPAPLDALVQAVNAAQEQVDMAIYNLSYPPLVDALIAAHERGVLVRLVVENENRSRSGPAALQDAGISVRADSPDGLMHNKFAVIDAADVWTGSMNFTANSNDEDANHLIHFHSTQLAQIFTAEFEEMFTQNRFGANSPRGDEMQGFIFDGVQVEVLFAPDDQPEERVIELIGSARQSVEMLAYSFTSDPIGNALLSKARDGVRVRVVQDAEQVTGTGSEYKYLSDSGLDIRLDACDGLMHHKVIILDGNTVVIGSYNFTKSANTRNDETLLVIRAPHLAAAFQQEFEALYAAAVTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y5F4</accession>
    <name>A0A0P6Y5F4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01355</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80523">
        <property type="protein sequence ID" value="KPL80523"/>
        <property type="gene ID" value="ADN00_01355"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="230" mass="25503" checksum="7DE13C635A7CD1DC" modified="2016-01-20" version="1">MVSGADLDPRALNAARLQVWPEEENSADCIASVLRLESHHSAAFVEDGRVAAFVDGFLTYSGEGVPRWEVDLLGTLADYRGQGLARRLIEDNLRAGWQRGASFSRALIQLENHASQRAFAACGFAPADGVVRLWVCSRPLSEPAPLPPGQHLVPVETFNYRGVWLEGKLSAQGLRAARAWLPQGGGQICGVLMPREREDLHQAAQNEGYAWVNDYQWWLLSRLEQGRKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y643</accession>
    <name>A0A0P6Y643_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Tad domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_10920</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063030.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10920"/>
    <dbReference type="EnsemblBacteria" id="KPL77059">
        <property type="protein sequence ID" value="KPL77059"/>
        <property type="gene ID" value="ADN00_10920"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028087">
        <property type="entry name" value="Tad_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13400">
        <property type="entry name" value="Tad"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="domain" description="Tad" evidence="2">
        <location>
            <begin position="10"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="442" mass="46920" checksum="9CA3C11BFF825370" modified="2016-01-20" version="1">MNFNQQRESGQVMVILALVLVGLLGFAALVVDGGTIFADRRFDQSAADASAVAGAVAAAQSIENQYITNGSFECSDSKVIAAMQDAADAAIDRSLDNRFTLTELPTQADLDAAKHGVYIACGEEDHDAWTQGYIDVMVDISSDVATTFAHMFYPGGFRNSVEAVVRVKPRTSGAFGYAIAVLSKDCQANYGNLKVSGNSLVTINNSGMFSNSCMKGNGNVKVTADEGIRFVDGYSADGGVTISPTPAQTAEELPTFTYPPADADCAKLSAYGEVKINNDSDNVTLNPGRYTGISVSKGKVNLKPGLYCVSGDIKLTGGIIAGDDVMFYLQKDGSKDTNFDSSGDAQINIRAPRSGPWYGMLIYMASGNKGSISLLGNSISEYKGTVYAPDGHVNVGGTSNQLGQFSTQIIAYTAEIFGTTTMEINFDDTIHYSNPSFLDMYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y6C4</accession>
    <name>A0A0P6Y6C4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MFS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_00025</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL80980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060909.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00025"/>
    <dbReference type="EnsemblBacteria" id="KPL80980">
        <property type="protein sequence ID" value="KPL80980"/>
        <property type="gene ID" value="ADN00_00025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="29"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="55"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="91"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="115"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="153"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="181"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="256"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="291"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="322"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="345"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="381"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="408"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="256"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL80980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="430" mass="47647" checksum="9F8B7849C405230A" modified="2016-01-20" version="1">MNTIRAIFRSSTFVPQEYKSNFLHLYFDTGWYGILNGSILTFIAVYAAHLGASSFQIGLITSVPAIINLAFTIPTGAWLEKQHLGEAVFKSSVINRVFYLLFIPLPWLFAPEVEIWILILITLVMSIPGVALAIGFNAFFAEAVPLKYRGHVAGIRNAVFAVTTTLTTLLCGWMLEEIQFPLNYQILFGIGLFGSLLSSVHLKFIKSIEPSKPELIAARSVEEEKRITRIRMRGDVRTRINKLSQSFHFDLLSGRFFRVMFLVFLFHLFQYLPAPIFPIQMVNVLDFSDQWISVGMAVFYLAMFLGSTQLSQITSKIGNQAALGLGVGLMGAYPLLLLASKEAVYFISASFLGGLAWSLAGGTIINYLLERVPAEDRPAHFAWYNIFLNAAILVGSTLGGPISEMIGLPQSLLLFGAGRILAGLLILWKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y6T1</accession>
    <name>A0A0P6Y6T1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Enoate reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_00710</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the N-terminal section; belongs to the NADH:flavin oxidoreductase/NADH oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061030.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00710"/>
    <dbReference type="EnsemblBacteria" id="KPL81144">
        <property type="protein sequence ID" value="KPL81144"/>
        <property type="gene ID" value="ADN00_00710"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3540"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001155">
        <property type="entry name" value="OxRdtase_FMN_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00724">
        <property type="entry name" value="Oxidored_FMN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidored_FMN" evidence="2">
        <location>
            <begin position="37"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="Oxidored_FMN" evidence="2">
        <location>
            <begin position="357"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_2" evidence="3">
        <location>
            <begin position="454"/>
            <end position="716"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00724"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL81144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="753" mass="83167" checksum="9F19C5C21F7F8A27" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YA26</accession>
    <name>A0A0P6YA26_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA-directed DNA polymerase</fullName>
            <ecNumber evidence="1">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_05280</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="1"/>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061928.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05280"/>
    <dbReference type="EnsemblBacteria" id="KPL78668">
        <property type="protein sequence ID" value="KPL78668"/>
        <property type="gene ID" value="ADN00_05280"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006134">
        <property type="entry name" value="DNA-dir_DNA_pol_B_multi_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042087">
        <property type="entry name" value="DNA_pol_B_thumb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023211">
        <property type="entry name" value="DNA_pol_palm_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00136">
        <property type="entry name" value="DNA_pol_B"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA_pol_B" evidence="4">
        <location>
            <begin position="343"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_pol_B" evidence="4">
        <location>
            <begin position="403"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_pol_B" evidence="4">
        <location>
            <begin position="554"/>
            <end position="674"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL78668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="739" mass="84170" checksum="46394DE27CCBFF14" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YBE4</accession>
    <name>A0A0P6YBE4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 11">Replicative DNA helicase</fullName>
            <ecNumber evidence="3 11">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">ADN00_04645</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the helicase family. DnaB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3 11"/>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04645"/>
    <dbReference type="EnsemblBacteria" id="KPL79244">
        <property type="protein sequence ID" value="KPL79244"/>
        <property type="gene ID" value="ADN00_04645"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.291"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990077">
        <property type="term" value="C:primosome complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006269">
        <property type="term" value="P:DNA replication, synthesis of RNA primer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00984">
        <property type="entry name" value="DnaB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036185">
        <property type="entry name" value="DNA_heli_DnaB-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007692">
        <property type="entry name" value="DNA_helicase_DnaB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007694">
        <property type="entry name" value="DNA_helicase_DnaB-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007693">
        <property type="entry name" value="DNA_helicase_DnaB-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016136">
        <property type="entry name" value="DNA_helicase_N/primase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00772">
        <property type="entry name" value="DnaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03796">
        <property type="entry name" value="DnaB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48024">
        <property type="entry name" value="SSF48024"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00665">
        <property type="entry name" value="DnaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51199">
        <property type="entry name" value="SF4_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 11" id="KW-0235">DNA replication</keyword>
    <keyword evidence="10 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8 11 13" id="KW-0347">Helicase</keyword>
    <keyword evidence="7 11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0639">Primosome</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SF4 helicase" evidence="12">
        <location>
            <begin position="177"/>
            <end position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008428"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU362085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KPL79244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="451" mass="51368" checksum="CCE303E83EC0F349" modified="2016-01-20" version="1">MDDQIKGPPHSRQAEEAVLGSVLINPESYYDVAQFLQPDDFYIIRNRWIWETFNRLHESRRPIDYLTVTEDLAQQAHLEEMGGPAYILSLINQTPTSLHAEAYGRLVEENAIRRRMLTSANELARLAYNQQNSVDTILNEAEKQIFGLSERRVQRDLQPISRVLSEVYDRVDLLSRRDDDIYGVPTGLIDLDYLLGGLQKSDLLIIAGRPGMGKTGFMLGVMKNAAQKHKKHVAMFSLEMSNEQLVQRLIAQETGIDTQRLRKGQLNDEEWPLFTHAIEVLSQTHIFLDDTPAITPLQLRTKCRRLHMEHNLDLIIVDYLQLMSGDSRNDNRVQEVSYISRNLKIMARELNVPVLVGAQLSRAVEQRADKKPILSDLRESGSLEQDADIVMFIHRPEMLENESPTKNIAEIIVAKHRNGPTHGGIQLVFLNNTARFENAATPARGQTQRPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YEL8</accession>
    <name>A0A0P6YEL8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Peptidase M42</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_01415</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="8">Binds 2 divalent metal cations per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase M42 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80533.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061177.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01415"/>
    <dbReference type="EnsemblBacteria" id="KPL80533">
        <property type="protein sequence ID" value="KPL80533"/>
        <property type="gene ID" value="ADN00_01415"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1037"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008007">
        <property type="entry name" value="Peptidase_M42"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023367">
        <property type="entry name" value="Peptidase_M42_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05343">
        <property type="entry name" value="Peptidase_M42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001123">
        <property type="entry name" value="PepA_GA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="224"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="190"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="225"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR001123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001123-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001123-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL80533.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="349" mass="37376" checksum="E5B9D996D5C575A0" modified="2016-01-20" version="1">MPLPTINLDDLLAFLTDLLRTPSPTGFAHLGIERVRAELAPLPGVQARLTRKGSLLVTLPGERADAPRALSAHVDTLGAMVKEIKASGRLELTNVGGLSWNGVEAEDCTVFTQSGAQIPGSLVPVKAAAHVYGSEVTTTERGPHSMEMRLDARTQSREETAALGIQVGDFVAFDPRVSQHNGFIRSRFLDDKSGVACMVAAVKALVAANLQPRQTTYLLFSNFEEVGHGGSAGLPADTAELVVIDMAAIGEGQNSDEYHATLCLKDSSGPYHHGLSSRLRQIAQQHGIDIRPDIYPYYASDGSAAWRAGHDLAVALIGPGVDASHHYERTHTDALADTTRWVLAYLLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YEQ2</accession>
    <name>A0A0P6YEQ2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">NH(3)-dependent NAD(+) synthetase</fullName>
            <ecNumber evidence="4 6">6.3.1.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">nadE</name>
        <name evidence="8" type="ORF">ADN00_01680</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 6">
            <text>ATP + deamido-NAD(+) + NH4(+) = AMP + diphosphate + H(+) + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:21188"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.1.5"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; NAD(+) biosynthesis; NAD(+) from deamido-NAD(+) (ammonia route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the NAD synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.1.5" evidence="4 6"/>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061225.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01680"/>
    <dbReference type="EnsemblBacteria" id="KPL80579">
        <property type="protein sequence ID" value="KPL80579"/>
        <property type="gene ID" value="ADN00_01680"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1095"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00333"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003952">
        <property type="term" value="F:NAD+ synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008795">
        <property type="term" value="F:NAD+ synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00553">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00193">
        <property type="entry name" value="NadE_ammonia_dep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022310">
        <property type="entry name" value="NAD/GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003694">
        <property type="entry name" value="NAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022926">
        <property type="entry name" value="NH(3)-dep_NAD(+)_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23090">
        <property type="entry name" value="PTHR23090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02540">
        <property type="entry name" value="NAD_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00552">
        <property type="entry name" value="nadE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 5" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 5" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD_synthase" evidence="7">
        <location>
            <begin position="30"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="49"/>
            <end position="56"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>deamido-NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL80579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="288" mass="31923" checksum="D3B180193E73A643" modified="2016-01-20" version="1">MKKLPITITRPKKKTISNLEINAELARQILTGFVRSEITRTGFTRAVLGLSGGIDSALSCFLAAEALGPENVLAVRMPYRASSADSLEDAQRVIDATGVQSMTVEITEMVDPLFAKFPDITNQRKGNIMARERMIILYDQSEAFKGLVVGTGNKTEILLGYSTLFGDSACALNPIGDLYKTQVRQLSRHLGIPSSVIDKAPSADLWAGQTDEGELGYTYAEVDQLLYLLIDERYTPQECVEAGFAEGFVRSVVERVRRNQFKRVLPPIAKLSNRTIGYDFLYLRDWGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GKL1</accession>
    <name>A0A0N8GKL1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_18215</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70002">
        <property type="protein sequence ID" value="KPL70002"/>
        <property type="gene ID" value="ADN00_18215"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="68" mass="7556" checksum="956DC5E93E5AA21D" modified="2016-01-20" version="1">MKMVLEKGLKNMITITLDLLETEKIDLISVHWFDHALETNQAPITSKVCGCKCTLKGAGILCFDSFPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GKM5</accession>
    <name>A0A0N8GKM5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_18910</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064601.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70114">
        <property type="protein sequence ID" value="KPL70114"/>
        <property type="gene ID" value="ADN00_18910"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="123" mass="13660" checksum="F9C9346A3C161C30" modified="2016-01-20" version="1">MAAAADLIPRFRRMIAEPTQDVYSDVVLIEVIESHPSQDPSGVFPEYADWEPSFDLNAAAAEIWSEKAAALACNFDFSADGSNFSRSQAYQQAIAQARYFSARRSPSTIRLQMAPRPEVEDVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GL13</accession>
    <name>A0A0N8GL13_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Protein GrpE</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">HSP-70 cofactor</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">grpE</name>
        <name evidence="7" type="ORF">ADN00_17620</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 4">Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 5">Belongs to the GrpE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000042">
        <property type="protein sequence ID" value="KPL71218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064367.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000042.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17620"/>
    <dbReference type="EnsemblBacteria" id="KPL71218">
        <property type="protein sequence ID" value="KPL71218"/>
        <property type="gene ID" value="ADN00_17620"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2788"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000774">
        <property type="term" value="F:adenyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00446">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.22.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01151">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000740">
        <property type="entry name" value="GrpE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013805">
        <property type="entry name" value="GrpE_coiled_coil"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009012">
        <property type="entry name" value="GrpE_head"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21237">
        <property type="entry name" value="PTHR21237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01025">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00773">
        <property type="entry name" value="GRPEPROTEIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51064">
        <property type="entry name" value="SSF51064"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58014">
        <property type="entry name" value="SSF58014"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01071">
        <property type="entry name" value="GRPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000639"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL71218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="190" mass="21660" checksum="8DF0C500095CB932" modified="2016-01-20" version="1">MDRETRKKKSQQVAAEEPQAAPEAPESEAPIPEAVVEINQLKDQLEVERKKSQENLDGWQRERADFSNYKKRIERDQVLLTSNLKFELIKKYLAVQDDLERALKNRPTEGEGAKWSEGIELVSRKLKTILEAEGIKAIEAEGQMFDPTLHEAITSEESPDHESGQVIEVLQQGYMLGDRVLRPALVRVAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GL36</accession>
    <name>A0A0N8GL36_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Flagellar basal-body rod protein FlgC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_17040</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="4 5">The basal body constitutes a major portion of the flagellar organelle and consists of four rings (L,P,S, and M) mounted on a central rod. The rod consists of about 26 subunits of FlgG in the distal portion, and FlgB, FlgC and FlgF are thought to build up the proximal portion of the rod with about 6 subunits each.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the flagella basal body rod proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064254.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17040"/>
    <dbReference type="EnsemblBacteria" id="KPL71402">
        <property type="protein sequence ID" value="KPL71402"/>
        <property type="gene ID" value="ADN00_17040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.470"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030694">
        <property type="term" value="C:bacterial-type flagellum basal body, rod"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001444">
        <property type="entry name" value="Flag_bb_rod_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010930">
        <property type="entry name" value="Flg_bb/hook_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006299">
        <property type="entry name" value="FlgC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00460">
        <property type="entry name" value="Flg_bb_rod"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06429">
        <property type="entry name" value="Flg_bbr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01395">
        <property type="entry name" value="FlgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flg_bb_rod" evidence="6">
        <location>
            <begin position="7"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="Flg_bbr_C" evidence="7">
        <location>
            <begin position="103"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF06429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL71402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="153" mass="16863" checksum="5350ACA852AE8C04" modified="2016-01-20" version="1">MSFWNTLRIGASALSAQRLRLDLISNNIANAQTTRTENGTPYQRQDVIFQPQGSNPNVPLPAPIAARLEQRGLLNSQFGGVEVNQIVTDTEEGPRVYDPQHPDADEEGYVTYPNVNLAFEMTNMLSATRSYEANLSVIDAAKRMALKALDIGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GLE6</accession>
    <name>A0A0N8GLE6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HAMP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_15830</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15830"/>
    <dbReference type="EnsemblBacteria" id="KPL72282">
        <property type="protein sequence ID" value="KPL72282"/>
        <property type="gene ID" value="ADN00_15830"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029151">
        <property type="entry name" value="Sensor-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103190">
        <property type="entry name" value="SSF103190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="29"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="140"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="3">
        <location>
            <begin position="507"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="930"/>
            <end position="960"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="943"/>
            <end position="960"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL72282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="960" mass="107847" checksum="859502119A905939" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GLX9</accession>
    <name>A0A0N8GLX9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Sugar-bind domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_14350</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SorC transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000034">
        <property type="protein sequence ID" value="KPL73746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063717.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000034.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL73746">
        <property type="protein sequence ID" value="KPL73746"/>
        <property type="gene ID" value="ADN00_14350"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007324">
        <property type="entry name" value="Sugar-bd_dom_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04198">
        <property type="entry name" value="Sugar-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sugar-bind" evidence="2">
        <location>
            <begin position="60"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL73746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="314" mass="34527" checksum="6E3235BEB219391D" modified="2016-01-20" version="1">MNAILLEKVAKLYYEDGMTQEKIAQKMRISRPKVSRLLTEARAEGVVQIIVSSLPNGFEDLERELEMKAGLLDSVVVRVSRPDDSMMVSQELGAAAAQYFERIVQDGDIVGFTWGNTLSVMADQISPIKLRQMLIVQMVGGMGDPFSDAHAGDIARRVAQTLNAKLAVMPAPGIVDTVEMCEAMRKNKHVSSALSLGAEVKVAFVGIGSFRKDALLMRNEDIISWQEVDPLIKRGAVGDIGLRFFDIQGRRLLSEIDQRIIGVELDVIRKLERVVGVAGGTQKYDAILGAVRGKYINSLVTDEETARRLVLDLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMS0</accession>
    <name>A0A0N8GMS0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Flagellin modification protein FlmA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_12065</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the polysaccharide synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063268.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12065"/>
    <dbReference type="EnsemblBacteria" id="KPL76074">
        <property type="protein sequence ID" value="KPL76074"/>
        <property type="gene ID" value="ADN00_12065"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3889"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd05237">
        <property type="entry name" value="UDP_invert_4-6DH_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003869">
        <property type="entry name" value="Polysac_CapD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020025">
        <property type="entry name" value="PseB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02719">
        <property type="entry name" value="Polysacc_synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03589">
        <property type="entry name" value="PseB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0966">Cell projection</keyword>
    <keyword evidence="3" id="KW-0969">Cilium</keyword>
    <keyword evidence="3" id="KW-0282">Flagellum</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Polysacc_synt_2" evidence="2">
        <location>
            <begin position="8"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL76074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="335" mass="37174" checksum="2891EDD8104164F2" modified="2016-01-20" version="1">MDWSKEIVLVTGGTGSFGKKFIRVLLEEYHPAKIIIYSRDELKQHEMRAAGYDHPSLRYFIGDVRDQERLRRALQGVTVCVHAAALKQVPACEYNPMEAIKTNILGSSNVIDAALDAGVRKVLALSTDKAVNPVNLYGATKLAAEKLFVQSNAYAGGKATRFSCVRYGNVVGSRGSVVPVFLKQRESGKVTITDERMTRFWISLDQGVRFVIRCVEQMRGGEVFVPKIPSMTVIDLAKSVAPEAEVNVIGIRPGEKLHEVLISDDEARTTVELDDMFVVQPAEALWFGHEWEKEGKPVADGFRYASNTNDEWLGVEEIKKIVAPIEEAYNQGTLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GN23</accession>
    <name>A0A0N8GN23_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_09875</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062834.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09875"/>
    <dbReference type="EnsemblBacteria" id="KPL76898">
        <property type="protein sequence ID" value="KPL76898"/>
        <property type="gene ID" value="ADN00_09875"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="365" mass="37951" checksum="3135CA28858DFE3D" modified="2016-01-20" version="1">MKETGAINLYPRMQVKPFDGMSVTAEVWAQAHDEHRQALNAHNLVSHGSGILTGLEVTANDPADQYVFISPGAAVDPAGNIIVVPEAVTYDFGESSEGTLYLVLGKGEREVGGVGSDTRYLQSEFVIAARPTMPKRPAVELARVTLSKSGAAIHNAANPLRPAADMLDLRFRSQAGPAVPPLARVLVMAAGSTGPAALSGWEHLARACQQAGAYRLVIDAAAFTPPDLGAYPLVYLGAGEGFAPEAGLVKALAAHLQQGKSLLLEALDAAAQPACQELLGLLQRAPAALPAGSPLLEEPYLFAAPPDGVGGSEVLLAGQVIYSTAAYSLAWAGRSAQGPAARADIRSAHEWGINLLRYSLKAAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNB9</accession>
    <name>A0A0N8GNB9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_08725</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000022">
        <property type="protein sequence ID" value="KPL77666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062610.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000022.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77666">
        <property type="protein sequence ID" value="KPL77666"/>
        <property type="gene ID" value="ADN00_08725"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL77666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="194" mass="22700" checksum="E3829B8540140F7B" modified="2016-01-20" version="1">MMNIEIWNEVDKRIQNPNEACQFIGKLMENSKDKTFNGLITANFTNTPSEIQNAINKFIYECNKTFELKAIYLEMNGFDINPSRWFFDLFGYEALPEDDSDLDWLSDWQSPDFPDVTLKGLESIQELFKQYNQEKADLNLDKPNQVLKNNHELATLMVMAKFCKLIDESLHNTHLGLHIYATAHDFEIIYHKHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNC0</accession>
    <name>A0A0N8GNC0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_08800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000022">
        <property type="protein sequence ID" value="KPL77674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062620.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000022.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08800"/>
    <dbReference type="EnsemblBacteria" id="KPL77674">
        <property type="protein sequence ID" value="KPL77674"/>
        <property type="gene ID" value="ADN00_08800"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="223"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="250"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="294"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="326"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="367"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="407" mass="46791" checksum="421E121392622F36" modified="2016-01-20" version="1">MNEKSRLTVKNYLRVFFGLSLLELLAVVGFFLSLPRDPKNVALLGMSYFRLGVLAVSLLALLVVLVVFLVYELRVTRADRFARFADWLRSSAIYSIATFLILNILMTAYLLSRWLGFDWIATDMQVRIRPFLGGWLLVCVQLLAVLLLSRRALREVEQNGRGGWEHFTAQGWPIFRGLLVFIAELYVLSVIGQLFRFFTPYREMLDFAIHEFHLDNEKNLPTFFSMGLMAISVLLMIYLGVRAITRREKFAFHWFFMAAMFIFLAVDEYKELHEQLGVIIRDTVKVQLTGFLNFAWYLPVIPILLLLLLAYLPFLRDMSPKQRKRILIGGIVFLFGAIGLESLGSKLLTDGLANYFQYVMLANVEEAVELTGLSIYIAALLQIIHEKILDQHAAKAIERRVEDLSKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNE8</accession>
    <name>A0A0N8GNE8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutaredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_08485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062555.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08485"/>
    <dbReference type="EnsemblBacteria" id="KPL77898">
        <property type="protein sequence ID" value="KPL77898"/>
        <property type="gene ID" value="ADN00_08485"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097573">
        <property type="term" value="F:glutathione oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutaredoxin" evidence="1">
        <location>
            <begin position="10"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="86" mass="10096" checksum="7E18BFBE22BE86F4" modified="2016-01-20" version="1">MTADESNPKIKVYGTRWCYDTRVSLAFLSKNHIRYQWIDIDKDEDGREFVERVNHGFRSVPTIVFPDGDILVEPTNEQLKEKLNLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNE9</accession>
    <name>A0A0N8GNE9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Cyclic pyranopterin monophosphate synthase</fullName>
            <ecNumber evidence="3 5">4.6.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Molybdenum cofactor biosynthesis protein C</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5 7" type="primary">moaC</name>
        <name evidence="7" type="ORF">ADN00_08540</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the conversion of (8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate to cyclic pyranopterin monophosphate (cPMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>(8S)-3',8-cyclo-7,8-dihydroguanosine 5'-triphosphate = cyclic pyranopterin phosphate + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:49580"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:59648"/>
            <dbReference type="ChEBI" id="CHEBI:131766"/>
            <dbReference type="EC" id="4.6.1.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homohexamer; trimer of dimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the MoaC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.6.1.17" evidence="3 5"/>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062564.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08540"/>
    <dbReference type="EnsemblBacteria" id="KPL77906">
        <property type="protein sequence ID" value="KPL77906"/>
        <property type="gene ID" value="ADN00_08540"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.712"/>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061799">
        <property type="term" value="F:cyclic pyranopterin monophosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01420">
        <property type="entry name" value="MoaC_PE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.640">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01224_B">
        <property type="entry name" value="MoaC_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023045">
        <property type="entry name" value="Mo_CF_biosynth-C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036522">
        <property type="entry name" value="MoaC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002820">
        <property type="entry name" value="Mopterin_CF_biosynth-C_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01967">
        <property type="entry name" value="MoaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55040">
        <property type="entry name" value="SSF55040"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00581">
        <property type="entry name" value="moaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 5" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MoaC" evidence="6">
        <location>
            <begin position="17"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="77"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="115"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012575"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL77906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="160" mass="17119" checksum="43F424ED841F5367" modified="2016-01-20" version="1">MVKHELTHLDDQGRAQMVDVGSKPDSERIAIARGEVCLKPETLELLEGGLMKKGDVLAVAKIAGIMAAKRTSELIPLCHPIAISQVEVNLALNMQLPGVDIEAKVKTFGKTGVEMEALTAVSVAALTVYDMVKAVEKTGRIQNIRLVEKHGGQSGDVINP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNI9</accession>
    <name>A0A0N8GNI9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_07030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062274.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78226">
        <property type="protein sequence ID" value="KPL78226"/>
        <property type="gene ID" value="ADN00_07030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="150" mass="16575" checksum="0784DB768E4DDD19" modified="2016-01-20" version="1">MADLELIRRLVQVGDFDTAVESLEKIVLEEPQNLEAWRMLADAYQDEKEKVRCLRQILILSPQDEAATQRLEEMEAEQAHPYEAALGGLRGGSQEDGDYLALSEPPKKAKANAIARGKDLVAGFLEDDKKFIALVAALVVLIIVTVIGML</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNT0</accession>
    <name>A0A0N8GNT0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_03390</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03390"/>
    <dbReference type="EnsemblBacteria" id="KPL78954">
        <property type="protein sequence ID" value="KPL78954"/>
        <property type="gene ID" value="ADN00_03390"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="763" mass="85276" checksum="A26AB2FB33F6B3E5" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNU4</accession>
    <name>A0A0N8GNU4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_04075</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061685.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04075"/>
    <dbReference type="EnsemblBacteria" id="KPL79066">
        <property type="protein sequence ID" value="KPL79066"/>
        <property type="gene ID" value="ADN00_04075"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="99" mass="11025" checksum="DCF66A06A8CFBDD9" modified="2016-01-20" version="1">MKILALERENPTAALRDFTPHLKAEAAAVWQLQQTGLLRQIDFNAEQHTAVLLLECDSKEQAEQVLGQMPLVQAGLIHFEIIPLAPYDGFARLFAQNSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GPI4</accession>
    <name>A0A0N8GPI4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_00060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL80986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060916.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00060"/>
    <dbReference type="EnsemblBacteria" id="KPL80986">
        <property type="protein sequence ID" value="KPL80986"/>
        <property type="gene ID" value="ADN00_00060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019206">
        <property type="entry name" value="DUF2085_TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09858">
        <property type="entry name" value="DUF2085"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="220"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="245"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="284"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="331" mass="37903" checksum="33B336B6C9DB6145" modified="2016-01-20" version="1">MITVTIYTHQDDITLDQLKADLDSLQSTVEHQVVTIDIDTDETLRKEMHGSTPLIKVGPYTLRPPFNRQDLEVTLRSAQDRVKYYQDDAEYIKRVERGRRVSGADRFSYWFSKQYMLVLNALVLLFVGLPFLAPVMMKQGLTGPARVIYAVYSPLCHQLSFRSWFLFGEQAYYPRELAGIEGVISYEELTQAETIDLNAARRFVGNEMVGYKVAFCQRDIAIYGGIFLFGVIFALTGRKIPGLKWYLWVLFGLVPIGIDGSSQLPSLAKSFFPSWMIIRESTPLLRSVTGLLFGITTAWFMYPMIEETMLETRKILGQKMEVLKQTQKANR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WK57</accession>
    <name>A0A0P6WK57_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_18610</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064543.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18610"/>
    <dbReference type="EnsemblBacteria" id="KPL70061">
        <property type="protein sequence ID" value="KPL70061"/>
        <property type="gene ID" value="ADN00_18610"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025645">
        <property type="entry name" value="DUF4349"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14257">
        <property type="entry name" value="DUF4349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132478" evidence="3">
        <location>
            <begin position="23"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="274"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="163"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL70061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="325" mass="35222" checksum="69E39C3D8B04E73D" modified="2016-01-20" version="1">MKKKTLIALVILAMTLAACSPAASTRSLNAVAEEKGYESMPMEAPAAAAPAMEMDSGFTANSYSGDTVQAQAVERIVIKNASLSIVVVDPAVAMDTIGKMAESMGGFIVSSNLYKSYTSQGVEVPAGDITIRVPADGLTSALDRVKGLVEDPKTDIRNENVSGQDVTQEYTDLQSRLRNLEEAEAQLREIMASATKTDDVLQIFNELTRVRQDIEVLQGQINYYNEASRLSSISVSIISKASVEPLTVAGWQPVGVARDALQALVDAFQFIVNALIWIVLFILPVLLLILLPIYLVFLAIRALVRRRKARKVAAAPQEEPKQPVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WMY8</accession>
    <name>A0A0P6WMY8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_16705</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16705"/>
    <dbReference type="EnsemblBacteria" id="KPL71350">
        <property type="protein sequence ID" value="KPL71350"/>
        <property type="gene ID" value="ADN00_16705"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.399"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011579">
        <property type="entry name" value="ATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004256">
        <property type="entry name" value="DUF234_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01637">
        <property type="entry name" value="ATPase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03008">
        <property type="entry name" value="DUF234"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase_2" evidence="1">
        <location>
            <begin position="2"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="DUF234" evidence="2">
        <location>
            <begin position="314"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL71350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="467" mass="53003" checksum="9725FDFEF4BC2272" modified="2016-01-20" version="1">MFINRQSELTQFNRLYQSDRAELLVLYGRRRVGKTELLRVFCQGKPHIYFIATLSSDSDQLAAFSHQIWNFLHPEGGQGPVFASWEAAFRALADLPGRPVVVLDEFTYLISGNKAIPSILQKVWDQQLKNASIMLVLCGSYIGMMESEVLEYRAPLYGRRTASTLLRALDFPSSANFFPQYPPDQRFLAWSILGGMPYYLLAFDPAMDIATNIRRAILDPQTAPLYSEPRLLLMEELHEPRNYFSILRAIAQGRTRLNEIALASGVGPASTVARYLDILQQMRLVTRRVPVTESQPEKSKKGLYQIDDHFLRFWFRYVHPNQAAIDLGLADAILEQRILTDLEHFAAAAFEEAAREHIAALARAGKLPFLSERIGGWWDRESEIDVLAVSQAQRALLAGECKWSVNPVGTNIVEDLKRKVSVLNQTGEWREVHYCLFSRSGFTPALLEQAGREQILLISIDQMLVEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WPP5</accession>
    <name>A0A0P6WPP5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_16250</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064093.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72036">
        <property type="protein sequence ID" value="KPL72036"/>
        <property type="gene ID" value="ADN00_16250"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="234" mass="25841" checksum="B1C9510BECA96E93" modified="2016-01-20" version="1">MNDILLNLIVLVVFAALGLLLFIFLQNRKKQKDAQFIQMAKEKGWEVERIQQPLLSGYRVRGRNTACEWTIESLAEASPRDAGPGSSEVGLSTRWWTKDVALADRGLVFGPVNNPGDAQMLASMGGAMFSKVIHGLLGEDADWAADLALVNAGSDQFRQKYLCLASEKEDAIRVLQPGIEKLMLALADRHRVVIKLTPAGLEIRIPTEQMLDRTSLDLMVNLGTAIVEIWLGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WQ05</accession>
    <name>A0A0P6WQ05_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UvrD-like helicase ATP-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_15120</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063873.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15120"/>
    <dbReference type="EnsemblBacteria" id="KPL72164">
        <property type="protein sequence ID" value="KPL72164"/>
        <property type="gene ID" value="ADN00_15120"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.726"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014016">
        <property type="entry name" value="UvrD-like_ATP-bd"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51198">
        <property type="entry name" value="UVRD_HELICASE_ATP_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvrD-like helicase ATP-binding" evidence="2">
        <location>
            <begin position="7"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="28"/>
            <end position="35"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL72164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="706" mass="80218" checksum="A8B03CD7959E09C0" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WSV5</accession>
    <name>A0A0P6WSV5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_16285</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16285"/>
    <dbReference type="EnsemblBacteria" id="KPL72115">
        <property type="protein sequence ID" value="KPL72115"/>
        <property type="gene ID" value="ADN00_16285"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="148" mass="16650" checksum="2067DC8BCCF09003" modified="2016-01-20" version="1">MADKKNKEIRTSVLLRKLFNAPDLETFIEVNATELDVPPFYVYLSDLCKAAGQVPEQVIRQAAIERTYGHQLFNGTRKPSRDKVIQLAFGLGLNLEDTQKLLQIAQKSLLYPKIKRDAAILYCLNHHKDVLETQSVLQSLGLSLLGGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WT93</accession>
    <name>A0A0P6WT93_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_18630</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70065">
        <property type="protein sequence ID" value="KPL70065"/>
        <property type="gene ID" value="ADN00_18630"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132625" evidence="2">
        <location>
            <begin position="22"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL70065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="69" mass="7086" checksum="ABE0F4D19DFDF745" modified="2016-01-20" version="1">MAVKLPRLLLTLLLLPTLVSAAGCQAGLPALLGSSPLETPQAPAATLPPPTCLLRSTPSPAFRSRTPKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WU11</accession>
    <name>A0A0P6WU11_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Sugar-bind domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_14340</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SorC transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000034">
        <property type="protein sequence ID" value="KPL73745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063716.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000034.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL73745">
        <property type="protein sequence ID" value="KPL73745"/>
        <property type="gene ID" value="ADN00_14340"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007324">
        <property type="entry name" value="Sugar-bd_dom_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04198">
        <property type="entry name" value="Sugar-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sugar-bind" evidence="2">
        <location>
            <begin position="72"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL73745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="324" mass="35714" checksum="0A258647E1AC4A8B" modified="2016-01-20" version="1">MNLPKNSSTGNIPLEELRLITRAAWLYYIQGLTQTEVADELNCSRIKVTRLISRAKSLGIVDIRINQPPGFFVDLEHQLISQYNLRDAVVTLDVPNGEPLRRALARAAVEWLTPNLNGERVVGISMGRTLAHFPEMIEPGQKTGTTFIEVMGASDSVNSGFSSYAVISRMAQLYGGQARLLDVPTFVSNQSIRDLLMGEKQIAERFEIARSCDILMTSVGTVDEDALLHQIGYISEEILQQLQKQKAVGDLLGHFIDQKGRPVPSPLDGRLMAVQLEDLKRIPYSVLVSGGQNKIQAMKAALLGNYVNVLITDVTTAQKLLAQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WVZ8</accession>
    <name>A0A0P6WVZ8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8">Acetolactate synthase</fullName>
            <ecNumber evidence="4 8">2.2.1.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">ADN00_19095</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>H(+) + 2 pyruvate = (2S)-2-acetolactate + CO2</text>
            <dbReference type="Rhea" id="RHEA:25249"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:58476"/>
            <dbReference type="EC" id="2.2.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="8">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
        <text evidence="8">Binds 1 thiamine pyrophosphate per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 1/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 1/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the TPP enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.6" evidence="4 8"/>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064635.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_19095"/>
    <dbReference type="EnsemblBacteria" id="KPL70142">
        <property type="protein sequence ID" value="KPL70142"/>
        <property type="gene ID" value="ADN00_19095"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3132"/>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00055"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00059"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003984">
        <property type="term" value="F:acetolactate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd02015">
        <property type="entry name" value="TPP_AHAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012846">
        <property type="entry name" value="Acetolactate_synth_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039368">
        <property type="entry name" value="AHAS_TPP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012000">
        <property type="entry name" value="Thiamin_PyroP_enz_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045229">
        <property type="entry name" value="TPP_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18968">
        <property type="entry name" value="PTHR18968"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00205">
        <property type="entry name" value="TPP_enzyme_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00118">
        <property type="entry name" value="acolac_lg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="6 8 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TPP_enzyme_N" evidence="11">
        <location>
            <begin position="5"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_M" evidence="9">
        <location>
            <begin position="196"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_C" evidence="10">
        <location>
            <begin position="389"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KPL70142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="564" mass="61421" checksum="A872BC2A6617594D" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WYJ3</accession>
    <name>A0A0P6WYJ3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Threonine--tRNA ligase</fullName>
            <ecNumber evidence="9">6.1.1.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Threonyl-tRNA synthetase</fullName>
            <shortName evidence="9">ThrRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">thrS</name>
        <name evidence="11" type="ORF">ADN00_13185</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + L-threonine + tRNA(Thr) = AMP + diphosphate + H(+) + L-threonyl-tRNA(Thr)</text>
            <dbReference type="Rhea" id="RHEA:24624"/>
            <dbReference type="Rhea" id="RHEA-COMP:9670"/>
            <dbReference type="Rhea" id="RHEA-COMP:9704"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78534"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.3" evidence="9"/>
    <dbReference type="EMBL" id="LGCL01000030">
        <property type="protein sequence ID" value="KPL75181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063486.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000030.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13185"/>
    <dbReference type="EnsemblBacteria" id="KPL75181">
        <property type="protein sequence ID" value="KPL75181"/>
        <property type="gene ID" value="ADN00_13185"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2888"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004829">
        <property type="term" value="F:threonine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006435">
        <property type="term" value="P:threonyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00771">
        <property type="entry name" value="ThrRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00184">
        <property type="entry name" value="Thr_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002320">
        <property type="entry name" value="Thr-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033728">
        <property type="entry name" value="ThrRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11451">
        <property type="entry name" value="PTHR11451"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01047">
        <property type="entry name" value="TRNASYNTHTHR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="SSF55186"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00418">
        <property type="entry name" value="thrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 9" id="KW-0820">tRNA-binding</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="10">
        <location>
            <begin position="200"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="293"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="344"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="470"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL75181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="595" mass="68887" checksum="06E7EFD6457EB4CD" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X000</accession>
    <name>A0A0P6X000_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_14190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063684.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000033.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74144">
        <property type="protein sequence ID" value="KPL74144"/>
        <property type="gene ID" value="ADN00_14190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023365">
        <property type="entry name" value="Sortase_dom-sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132744" evidence="1">
        <location>
            <begin position="30"/>
            <end position="228"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="228" mass="24098" checksum="275F23B8E2CB07BD" modified="2016-01-20" version="1">MKLASKKLVQAIVLIGLGLALMGASPALAPVAVTGVGSSVTDPASLPALNEFIDAVQGGDAQRLAGLYVEDVLALPVVQQPAGDPVFVSSRDGEVTQFMLADQFGNTGVLAHNHLAGEAFFDIQPGDEIVLIFGNGSQAAYRVSQMQRYQALSPNSPYSNFIDLSDASQKQISATELFHRTFGAGEGNLVLQTCIWQGNEPSWGRLFIIAEPVPASQLAFEGLRVTVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X1K5</accession>
    <name>A0A0P6X1K5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063505.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000031.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13275"/>
    <dbReference type="EnsemblBacteria" id="KPL74812">
        <property type="protein sequence ID" value="KPL74812"/>
        <property type="gene ID" value="ADN00_13275"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1137"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004311">
        <property type="term" value="F:farnesyltranstransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016117">
        <property type="term" value="P:carotenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00683">
        <property type="entry name" value="Trans_IPPS_HH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008949">
        <property type="entry name" value="Isoprenoid_synthase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002060">
        <property type="entry name" value="Squ/phyt_synthse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019845">
        <property type="entry name" value="Squalene/phytoene_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044843">
        <property type="entry name" value="Trans_IPPS_bact-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033904">
        <property type="entry name" value="Trans_IPPS_HH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00494">
        <property type="entry name" value="SQS_PSY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01212">
        <property type="entry name" value="Phytoene_synthase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48576">
        <property type="entry name" value="SSF48576"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01044">
        <property type="entry name" value="SQUALEN_PHYTOEN_SYN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01045">
        <property type="entry name" value="SQUALEN_PHYTOEN_SYN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="302" mass="34827" checksum="409DB534357EB3C9" modified="2016-01-20" version="1">MSAIQQSQVINLQQAQSSTEEIIRQHSRTFFFATALLPRAKRSAIRALYAFCRTTDDLVDRESATLDELEAWRSQNTLSFEEQTDPVLYYWGKIRSQYQVDSRYENELIDGVRKDLEKTRYQTWADLQQYCYLVASTVGLLSMPIIGLAHRATPEQAAPYAVTLGIALQLTNILRDIKEDKDRGRIYLPEEDLRQFGLTSDDILREVYDHRFISLMKFQIQRARQLYRQALPGILLLHPSVRLAVGASAILYRAILDEIEAIQYNVFQQRAHTSALKKIAMLPSILLTINFLKRPKLDPTKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X237</accession>
    <name>A0A0P6X237_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 13">Phosphoenolpyruvate-protein phosphotransferase</fullName>
            <ecNumber evidence="5 13">2.7.3.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 13">Phosphotransferase system, enzyme I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="20" type="ORF">ADN00_11540</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13">
            <text>L-histidyl-[protein] + phosphoenolpyruvate = N(pros)-phospho-L-histidyl-[protein] + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:23880"/>
            <dbReference type="Rhea" id="RHEA-COMP:9745"/>
            <dbReference type="Rhea" id="RHEA-COMP:9746"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:29979"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:64837"/>
            <dbReference type="EC" id="2.7.3.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 13 16">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13">Belongs to the PEP-utilizing enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.3.9" evidence="5 13"/>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063165.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11540"/>
    <dbReference type="EnsemblBacteria" id="KPL76580">
        <property type="protein sequence ID" value="KPL76580"/>
        <property type="gene ID" value="ADN00_11540"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1009"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008965">
        <property type="term" value="F:phosphoenolpyruvate-protein phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.274.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008279">
        <property type="entry name" value="PEP-util_enz_mobile_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018274">
        <property type="entry name" value="PEP_util_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000121">
        <property type="entry name" value="PEP_util_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023151">
        <property type="entry name" value="PEP_util_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036637">
        <property type="entry name" value="Phosphohistidine_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024692">
        <property type="entry name" value="PTS_EI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006318">
        <property type="entry name" value="PTS_EI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008731">
        <property type="entry name" value="PTS_EIN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036618">
        <property type="entry name" value="PtsI_HPr-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05524">
        <property type="entry name" value="PEP-utilisers_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00391">
        <property type="entry name" value="PEP-utilizers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02896">
        <property type="entry name" value="PEP-utilizers_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000732">
        <property type="entry name" value="PTS_enzyme_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47831">
        <property type="entry name" value="SSF47831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52009">
        <property type="entry name" value="SSF52009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01417">
        <property type="entry name" value="PTS_I_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00742">
        <property type="entry name" value="PEP_ENZYMES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00370">
        <property type="entry name" value="PEP_ENZYMES_PHOS_SITE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="13" id="KW-0418">Kinase</keyword>
    <keyword evidence="13 16" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11 13 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 13" id="KW-0598">Phosphotransferase system</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 13" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="13" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 13" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PEP-utilisers_N" evidence="19">
        <location>
            <begin position="5"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers" evidence="17">
        <location>
            <begin position="153"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers_C" evidence="18">
        <location>
            <begin position="256"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="PEP binding" evidence="15">
        <location>
            <begin position="454"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="14">
        <location>
            <position position="189"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="14">
        <location>
            <position position="502"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="296"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="332"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="431"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="16">
        <location>
            <position position="455"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="465"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00016544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00033235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRNR" id="PIRNR000732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000732-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR000732-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR000732-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="Pfam" id="PF00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="Pfam" id="PF02896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="Pfam" id="PF05524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KPL76580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="575" mass="62947" checksum="BE6529023CE7D03E" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X2M8</accession>
    <name>A0A0P6X2M8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">3-demethylubiquinone-9 3-methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062869.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10050"/>
    <dbReference type="EnsemblBacteria" id="KPL76927">
        <property type="protein sequence ID" value="KPL76927"/>
        <property type="gene ID" value="ADN00_10050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2472"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06588">
        <property type="entry name" value="PhnB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009725">
        <property type="entry name" value="3_dmu_93_MTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028973">
        <property type="entry name" value="PhnB-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06983">
        <property type="entry name" value="3-dmu-9_3-mt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF021700">
        <property type="entry name" value="3_dmu_93_MTrfase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0830">Ubiquinone</keyword>
    <feature type="domain" description="3-dmu-9_3-mt" evidence="1">
        <location>
            <begin position="2"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="157" mass="17295" checksum="EA65A2F7B6EA655D" modified="2016-01-20" version="1">MQKITPSLWFDSNAEEAVAFYTSIFKNSQIDAVSYYGEEGPGPAGTVMTIGFTLDGQQFEAINGGPYFSFTPAISFTVNCQDQAEVDALWDALSAGGSTEQCGWLKDKFGLSWQIVPTVLGEMMQDKDPQKVRRVTKAMLQMVKLDIALLKQAYEQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X377</accession>
    <name>A0A0P6X377_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 9">Gluconokinase</fullName>
            <ecNumber evidence="4 9">2.7.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ADN00_09220</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + D-gluconate = 6-phospho-D-gluconate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19433"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18391"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58759"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.12"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate acid metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the gluconokinase GntK/GntV family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.12" evidence="4 9"/>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062702.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09220"/>
    <dbReference type="EnsemblBacteria" id="KPL77302">
        <property type="protein sequence ID" value="KPL77302"/>
        <property type="gene ID" value="ADN00_09220"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4078"/>
    <dbReference type="UniPathway" id="UPA00251">
        <property type="reaction ID" value="UER00316"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046316">
        <property type="term" value="F:gluconokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02021">
        <property type="entry name" value="GntK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031322">
        <property type="entry name" value="Shikimate/glucono_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006001">
        <property type="entry name" value="Therm_gnt_kin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43442">
        <property type="entry name" value="PTHR43442"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01202">
        <property type="entry name" value="SKI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01313">
        <property type="entry name" value="therm_gnt_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 9" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL77302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="166" mass="18454" checksum="6A9C621B54378FBF" modified="2016-01-20" version="1">MKTNFFIIMGVSGCGKTSVGKALAERLGWDFYDADDYHPAENVAKMASGIPLNDDDRAPWLRELHKLIAGSLAQGRPGVLACSALKERYRRVLLAGNPGVQLVHLKGSYELIWSRMNARAAHYMKPHMLRSQFEALEEPADALVVDISLPVEEIVERILAWHSGVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X386</accession>
    <name>A0A0P6X386_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_09345</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062725.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09345"/>
    <dbReference type="EnsemblBacteria" id="KPL77320">
        <property type="protein sequence ID" value="KPL77320"/>
        <property type="gene ID" value="ADN00_09345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="190"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="250"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL77320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="467" mass="51625" checksum="AB9E5FB1BC6B0899" modified="2016-01-20" version="1">MHRSIFFKLTVAFVLVAVISTFTIMIVLRATNLDRFNRFVIDQLTSDVQEGLTQYYAANSSWEGVQEYWQTARYSFMNPGGGPPPENREGEVRHPEDRRNFFALIDTNGFVVLAAEPDYPLGMRVSEELIASGTSIQYEGQVIGTMLPLPRDPQLTPEETRFIERSNRAVLEATLIAVAIAVVLAVILSRTMARPLRQLTRAAQNMASGDLEQEVEVRSKDELGELAAAFNQMSLEVSRANKQRRQMTADIAHDLRTPLTVIAGYIESMRDGVLKPTPQRLSLIYNEIERLEALVNDLRLLSQVDAGELPIHPQSISPQTILERAALPFQHRAEQNQIAIQLHAPEGLPDLNLDEARMMQVLSNLIINAFQFTPAGGQITMSAELKDGAVCFSVSDTGQGIPPEELNLVFDRFYRVDRSRQDAGGGSGLGLAIVKALVEAQGGRVAVESVVGEGTTFRIVFPVAPQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X452</accession>
    <name>A0A0P6X452_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha-amylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_08075</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062479.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77832">
        <property type="protein sequence ID" value="KPL77832"/>
        <property type="gene ID" value="ADN00_08075"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.615"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aamy" evidence="1">
        <location>
            <begin position="290"/>
            <end position="715"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="1155" mass="133781" checksum="041A2C432286FCD3" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X4A0</accession>
    <name>A0A0P6X4A0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_08535</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062563.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08535"/>
    <dbReference type="EnsemblBacteria" id="KPL77905">
        <property type="protein sequence ID" value="KPL77905"/>
        <property type="gene ID" value="ADN00_08535"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.711"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007059">
        <property type="term" value="P:chromosome segregation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003768">
        <property type="entry name" value="ScpA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023093">
        <property type="entry name" value="ScpA-like_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33969">
        <property type="entry name" value="PTHR33969"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02616">
        <property type="entry name" value="SMC_ScpA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="261" mass="29412" checksum="577C6387429AB86A" modified="2016-01-20" version="1">MSFQVAAHQTERYQVATSVYTGPLDLLLELIENAQLDITTLALAQVTDQYLAFMKEIRDRDAAEVSAFLVIAARLVQIKSAALLPRPPAVDASADELEDGEALAQQLILYRRFKQISIWLLSRENASLRTHLRVAPVSVKIEPRLDLTGVTLRDVVLAARDTLSGSPDLPELSRVVNMPRITIRDKIHTIIETIKHTTRTTFQHLLIRRNRVEVVVTFLALLELIKRHVVEAEQQELFGEIEFSPVGTLDENEIGDLEFSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X564</accession>
    <name>A0A0P6X564_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase_M6 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_18380</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064508.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18380"/>
    <dbReference type="EnsemblBacteria" id="KPL70031">
        <property type="protein sequence ID" value="KPL70031"/>
        <property type="gene ID" value="ADN00_18380"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2983"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008757">
        <property type="entry name" value="Peptidase_M6-like_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05547">
        <property type="entry name" value="Peptidase_M6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132859" description="Peptidase_M6 domain-containing protein" evidence="1">
        <location>
            <begin position="25"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M6" evidence="2">
        <location>
            <begin position="450"/>
            <end position="601"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL70031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="668" mass="74295" checksum="17BD44F8A73DEF8A" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5V0</accession>
    <name>A0A0P6X5V0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Galactose/methyl galactoside import ATP-binding protein MglA</fullName>
            <ecNumber evidence="4">7.5.2.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_09200</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Part of the ABC transporter complex MglABC involved in galactose/methyl galactoside import. Responsible for energy coupling to the transport system.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>ATP + D-galactose(out) + H2O = ADP + D-galactose(in) + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:60156"/>
            <dbReference type="ChEBI" id="CHEBI:4139"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.5.2.11"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">The complex is composed of two ATP-binding proteins (MglA), two transmembrane proteins (MglC) and a solute-binding protein (MglB).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the ABC transporter superfamily. Galactose/methyl galactoside importer (TC 3.A.1.2.3) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.5.2.11" evidence="4"/>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062699.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77299">
        <property type="protein sequence ID" value="KPL77299"/>
        <property type="gene ID" value="ADN00_09200"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4074"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043211">
        <property type="term" value="F:ABC-type carbohydrate transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015862">
        <property type="entry name" value="ABC_transpr_MglA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43790:SF7">
        <property type="entry name" value="PTHR43790:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 3 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="8"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="253"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="40"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU367029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL77299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="500" mass="56019" checksum="AF5055337C33A829" modified="2016-01-20" version="1">MTEATYLLEMNNISKSFPGVQALDNVKLHIRRGSVHALVGENGAGKSTLMKCLFGIYHKDEGDILLEGKPVQFTNAKQALDHGVSMVHQELNQVRQTRIMDNIWLGRFPEKGLFIDEDKMYADTLAIFKDLEIELDPRRKVDTLSVSESQMVEIAKAVSYNAKIIVMDEPTSSLTEKEVNHLFKIISALRARGAGIIYISHKMEEILKIADDVTVMRDGHWIRTIPATEVTIEEIIRLMVGRDLTNRFPPKTNRPSDTILEVRDFTATDPRSIKEVSFDLRKGEILGVAGLVGSKRTELVESIFGLHNLQSGSLNLNGKDIKISNPHQAIKKGFALVTEERRATGIFHVANIRFNSTIANIETYVTRYRLLNDRARTKDTKWAIDSLRIKTPSQKTRIESLSGGNQQKVILGRWLLTGPEVLLMDEPTRGIDVGAKFEIYQLMLDLANNGKAIIMVSSEMPELLGITDRILVMSNGRVAGIVETANTNQEEILTLAAKYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X651</accession>
    <name>A0A0P6X651_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FMN_bind domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063531.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000031.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13415"/>
    <dbReference type="EnsemblBacteria" id="KPL74832">
        <property type="protein sequence ID" value="KPL74832"/>
        <property type="gene ID" value="ADN00_13415"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1170"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007329">
        <property type="entry name" value="FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04205">
        <property type="entry name" value="FMN_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00900">
        <property type="entry name" value="FMN_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN_bind" evidence="1">
        <location>
            <begin position="59"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="135" mass="14621" checksum="AFA44F0C333715F3" modified="2016-01-20" version="1">MLGWIIAMVIVAALGIAGRIGWSHLEKEHHEARNLPLKVIDFSTLAEGTYQGAYEGGMYKWRANQCQVTVSAGKVADIQLTGSMDPDKERAGAQMLYDRVIQAQSLQVDTISGATLTSKAYLKGIENALVQAQNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X727</accession>
    <name>A0A0P6X727_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_06515</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062153.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78856">
        <property type="protein sequence ID" value="KPL78856"/>
        <property type="gene ID" value="ADN00_06515"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="364" mass="41491" checksum="D73296B1761C0B90" modified="2016-01-20" version="1">MPPVKKILFFVPCTPYFPSGIVRVEQFFNLLEKDGYAYELLNMIHPRSQMLLERLDRSAWGKQKITDFVIRVAIHLVFLPYQYLQMLKVAAQANKFDIIFIQSNLMPAPIVDFIQRKNPRIIYDFDDAVFLRNQARAIHIISKAWKVFAGSHYNLDFARRHNPASILIPSAVDLAEYPPLTANPERSDPIRIGWIGGASTLKYLRHLVAPLENLARKGYHLQFLITGSRGSEKLIPRVEGVELKVIEEYTHAEIPSLADKMDIGVMPLDDGPWEKGKCGLKLLIYMAAGKPCLSSPVGENQIIIRDGENGFLASSAQEWEQQLEALISNPDLYQRIARQGRKTVEEHYSVMKVYEMIRAELVDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X755</accession>
    <name>A0A0P6X755_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Phosphate ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">pstB</name>
        <name evidence="5" type="ORF">ADN00_18030</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL69971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064437.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18030"/>
    <dbReference type="EnsemblBacteria" id="KPL69971">
        <property type="protein sequence ID" value="KPL69971"/>
        <property type="gene ID" value="ADN00_18030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2907"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015415">
        <property type="term" value="F:ATPase-coupled phosphate ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03260">
        <property type="entry name" value="ABC_PstB_phosphate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005670">
        <property type="entry name" value="Phosp_transpt1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43423">
        <property type="entry name" value="PTHR43423"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00972">
        <property type="entry name" value="3a0107s01c2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="7"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="39"/>
            <end position="46"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL69971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="256" mass="28941" checksum="EAD56F6E5C17C416" modified="2016-01-20" version="1">MTLETKLKVIDFNLYYGNFQALNNITLDIPENRITAIIGPSGCGKSTFVRSINRMNDLIPSVRTHGEMYMDEENLFDINVVDLRRRVGMVFQRPNPFPKSVYDNVAYGPRMHGIKNTSDLNDIVERSLRAAALWDEVKDDLNKSGLALSGGAQQRLCIARALAVEPEMILMDEPASALDPLATLHIEELMQTLKENYTIVIVTHNMQQAARSSDFTAFFHMGEDRAGYLVEYGPTEEIFTNPRQKLTEEYISGRFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X775</accession>
    <name>A0A0P6X775_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_17855</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000043">
        <property type="protein sequence ID" value="KPL70900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064401.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000043.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70900">
        <property type="protein sequence ID" value="KPL70900"/>
        <property type="gene ID" value="ADN00_17855"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="132" mass="14945" checksum="BCB3BC1ABD1946D3" modified="2016-01-20" version="1">MRIYLSLQYHPDQRNRPWIEEISTMLSEMGHTTFCPARDIQDWGGVRPSPAEFMQRVFTEIAASNALLIDLTEKGVGIGIEAGFAHTRSIPIITVAQTGCDISRTLQGISSKIYWYDSTADLRRFFDTVFAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X823</accession>
    <name>A0A0P6X823_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Abhydrolase_5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_04720</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79158">
        <property type="protein sequence ID" value="KPL79158"/>
        <property type="gene ID" value="ADN00_04720"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.307"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029059">
        <property type="entry name" value="AB_hydrolase_5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12695">
        <property type="entry name" value="Abhydrolase_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Abhydrolase_5" evidence="1">
        <location>
            <begin position="71"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="251" mass="26723" checksum="C511F67348C2B2A2" modified="2016-01-20" version="1">MRRRQMKLKKVLVIALGILLLAVVGFVVWGSTPLGPDDAALAALQSDAQVTVSQMPGVIVFAPVGDFPTKGLVFYPGGRVDYRAYAPTLKEIARGGVLVALPAMPLNLAVFSPNRAQEIIYAYPQIEQWVVGGHSLGGAMAAEFAADRADQVDGLVLWGSYPADQNDLTQSGLHVLSVYGSEDGQVEKIRASSVLLPENAVFLEIEGGNHAQFGSYGTQPGDGAASISAVEQWRRAAEAVLELMESLETQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X8A1</accession>
    <name>A0A0P6X8A1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_07560</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062371.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07560"/>
    <dbReference type="EnsemblBacteria" id="KPL78304">
        <property type="protein sequence ID" value="KPL78304"/>
        <property type="gene ID" value="ADN00_07560"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032255">
        <property type="entry name" value="HBM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024478">
        <property type="entry name" value="HlyB_4HB_MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12729">
        <property type="entry name" value="4HB_MCP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01358">
        <property type="entry name" value="HBM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0807">Transducer</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="13"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="300"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="6">
        <location>
            <begin position="322"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="6">
        <location>
            <begin position="382"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="5">
        <location>
            <begin position="468"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="782"/>
            <end position="814"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL78304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="814" mass="88601" checksum="23D4C5391FA90778" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9Q7</accession>
    <name>A0A0P6X9Q7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_10195</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062897.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10195"/>
    <dbReference type="EnsemblBacteria" id="KPL76950">
        <property type="protein sequence ID" value="KPL76950"/>
        <property type="gene ID" value="ADN00_10195"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2503"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007318">
        <property type="entry name" value="Phopholipid_MeTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04191">
        <property type="entry name" value="PEMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="40"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="83"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="180"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL76950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="229" mass="26422" checksum="B00FC27AD2BABE57" modified="2016-01-20" version="1">MKPSPVASRQLIFTVIKFYLLAAALLMLLFFLPAGTFQYWQAWVYMVVILGPMLLVMVYLLRNDPELLARRMQFRERAADQNLITRLSILPFLAAFILPGFDRRFGWSHVPVWLAVTGQLLVLSGYVINFLVFRENSYASRIVEVSEGQTVISSGPYAIVRHPMYLGVMLLYRLSPLALGSYWGMIPALMIIPFIIVRIISEEKLLVKELKGYAEYRQKVRYRLIPGIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAP3</accession>
    <name>A0A0P6XAP3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_04980</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061850.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79200">
        <property type="protein sequence ID" value="KPL79200"/>
        <property type="gene ID" value="ADN00_04980"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.364"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="12"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="48"/>
            <end position="55"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL79200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="234" mass="26013" checksum="C09ED42076C46C5C" modified="2016-01-20" version="1">MNPEANQPQPVIRLRQVHRQFKVGFETVNALDGVDLDIRRGEFFGITGPSGSGKSTMLYLVGGMDRPTAGRIEVIGQDISQMDENQLAAFRRTMVGFVYQSFHLIPTMTALQNVEFPMIFSQVPRKERRERAAELLEKIGLGNRMQHKPTEMSGGQRQRVAIARALTNHPEVLLADEPTGNLDSRSGAEVVELLHELIKTQGVTVLIVSHDPAVIASTTRHIQLQDGQIQHSES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAS5</accession>
    <name>A0A0P6XAS5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF5110 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_04185</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the glycosyl hydrolase 31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04185"/>
    <dbReference type="EnsemblBacteria" id="KPL79237">
        <property type="protein sequence ID" value="KPL79237"/>
        <property type="gene ID" value="ADN00_04185"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.193"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033403">
        <property type="entry name" value="DUF5110"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000322">
        <property type="entry name" value="Glyco_hydro_31"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17137">
        <property type="entry name" value="DUF5110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01055">
        <property type="entry name" value="Glyco_hydro_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5110" evidence="3">
        <location>
            <begin position="698"/>
            <end position="767"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL79237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="829" mass="93530" checksum="916EDC54A2421104" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBC4</accession>
    <name>A0A0P6XBC4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FeoA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_15935</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL71991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15935"/>
    <dbReference type="EnsemblBacteria" id="KPL71991">
        <property type="protein sequence ID" value="KPL71991"/>
        <property type="gene ID" value="ADN00_15935"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007167">
        <property type="entry name" value="Fe-transptr_FeoA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038157">
        <property type="entry name" value="FeoA_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008988">
        <property type="entry name" value="Transcriptional_repressor_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04023">
        <property type="entry name" value="FeoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00899">
        <property type="entry name" value="FeoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50037">
        <property type="entry name" value="SSF50037"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FeoA" evidence="2">
        <location>
            <begin position="6"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL71991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="80" mass="8593" checksum="81F698D65A8B95BE" modified="2016-01-20" version="1">MGDCMMPLSMVNQNQEVKLVAIQGGLKMKQRLADLGLNIGMSIRVLKKASGGPMIIAVKESRLALGWGMANRILVEPLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBD9</accession>
    <name>A0A0P6XBD9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ADN00_10370</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10370"/>
    <dbReference type="EnsemblBacteria" id="KPL77072">
        <property type="protein sequence ID" value="KPL77072"/>
        <property type="gene ID" value="ADN00_10370"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004014">
        <property type="term" value="F:adenosylmethionine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008295">
        <property type="term" value="P:spermidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003826">
        <property type="entry name" value="AdoMetDC_fam_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016067">
        <property type="entry name" value="S-AdoMet_deCO2ase_core"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02675">
        <property type="entry name" value="AdoMet_dc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56276">
        <property type="entry name" value="SSF56276"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="2" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="9" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0704">Schiff base</keyword>
    <keyword evidence="4" id="KW-0745">Spermidine biosynthesis</keyword>
    <keyword evidence="6" id="KW-0865">Zymogen</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL77072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="128" mass="14587" checksum="D825FCD33BA36234" modified="2016-01-20" version="1">MRMPEPEKTRDAEPWGWHLVLNIYDCLPEQICSADVIRDYVVDLCDLIEMRRFGEPTIVNFGEDPRVSGYSLVQLIETSNVCAHFAEQTNSAYLDIFSCKKFDPEIAARFTIETFGAQKASGVFVSRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XCH7</accession>
    <name>A0A0P6XCH7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_01765</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061240.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80593">
        <property type="protein sequence ID" value="KPL80593"/>
        <property type="gene ID" value="ADN00_01765"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL80593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="70" mass="8248" checksum="76B2CB307AA3B995" modified="2016-01-20" version="1">MSDSVECYAGASYPQRPLAVRVGEERLEVLEILREYRLPGGKGFRVRVQGDRIYELQYQEYRDEWLVIPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XD03</accession>
    <name>A0A0P6XD03_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Maebl</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_15060</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000036">
        <property type="protein sequence ID" value="KPL73103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063858.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000036.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL73103">
        <property type="protein sequence ID" value="KPL73103"/>
        <property type="gene ID" value="ADN00_15060"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1877"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004540">
        <property type="term" value="F:ribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041966">
        <property type="entry name" value="LOTUS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021139">
        <property type="entry name" value="NYN_MARF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025605">
        <property type="entry name" value="OST-HTH/LOTUS_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01936">
        <property type="entry name" value="NYN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12872">
        <property type="entry name" value="OST-HTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51644">
        <property type="entry name" value="HTH_OST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH OST-type" evidence="2">
        <location>
            <begin position="171"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="154"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL73103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="250" mass="27733" checksum="A1B2CF9BC47303A4" modified="2016-01-20" version="1">MTDSNESGADRRIAILIDGDNAQPSLISNMLAETGKYGLLTIRRIYGDWTTSNMGGWKDTLQTYAVQPIQQFRYTIGKNATDSAMIIDAMDILYEGVVDGFCLVSSDSDYTRLATRIREKGFFVMGIGKKTTPRAFVNACNVFVFTENLTPGKTYTKPTTGQKTNGSAEPETPDPTPLLNRAFDLAVQDDGWAFLGVMGQHLRQLDPSFDPRTYGFKQLSLLIRALPNIYKVREVKQANGASIISVRHKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XD44</accession>
    <name>A0A0P6XD44_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aryl-alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000003">
        <property type="protein sequence ID" value="KPL80822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061122.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000003.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80822">
        <property type="protein sequence ID" value="KPL80822"/>
        <property type="gene ID" value="ADN00_01110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="37"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="348" mass="38951" checksum="0F0FCDB6AE861E9B" modified="2016-01-20" version="1">MDHLIAHPEFFKAPLDIFEFNGMPYLRMGGSGLWTSKIGLGTWKFGRPETGDQSRVDQATALRIFDRALELGVTFWDTAPRYNNASGNAERIIGEWLKANPDQRRNIVIATKVYGGMDGITPNHCRLTRGNIKESVYASLERMNIETIDLFYFHHYDPFTPPEESFSAIEDLVREDLIRYLAVSNFTVDQLRAYQTIECANGIRSRIIAIQNQFDILRKEPPEYAGVLDFIQKSNLSFIAYSPLAEGFLTSRYLDPARAGVGDRVFDQGSLPELASPQNLIKLRQLNALATEWALDLSQLVLAYTLTLPGIGSLIPASSSVQQLESNARVAKITLTDEQKSTVKAIVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XF87</accession>
    <name>A0A0P6XF87_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">dTDP-4-dehydrorhamnose reductase</fullName>
            <ecNumber evidence="2">1.1.1.133</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_06540</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the reduction of dTDP-6-deoxy-L-lyxo-4-hexulose to yield dTDP-L-rhamnose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>dTDP-beta-L-rhamnose + NADP(+) = dTDP-4-dehydro-beta-L-rhamnose + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:21796"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57510"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:62830"/>
            <dbReference type="EC" id="1.1.1.133"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate biosynthesis; dTDP-L-rhamnose biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the dTDP-4-dehydrorhamnose reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.133" evidence="2"/>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062158.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06540"/>
    <dbReference type="EnsemblBacteria" id="KPL78861">
        <property type="protein sequence ID" value="KPL78861"/>
        <property type="gene ID" value="ADN00_06540"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1812"/>
    <dbReference type="UniPathway" id="UPA00124"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008831">
        <property type="term" value="F:dTDP-4-dehydrorhamnose reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019305">
        <property type="term" value="P:dTDP-rhamnose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005913">
        <property type="entry name" value="dTDP_dehydrorham_reduct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029903">
        <property type="entry name" value="RmlD-like-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10491">
        <property type="entry name" value="PTHR10491"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04321">
        <property type="entry name" value="RmlD_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01214">
        <property type="entry name" value="rmlD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RmlD_sub_bind" evidence="3">
        <location>
            <begin position="1"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU364082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL78861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="286" mass="32330" checksum="1D0F6CA704660FF2" modified="2016-01-20" version="1">MKILLVGCNGQLGWELQRTLPYFGELLSVDFPEIDLSNADSVQSVVTSFKPHVVINAAAYTDVDRAESQPELCMKVNCDGPKFLAEACDQNQSVLVHYSTDYVFSGETDRPYREDDQPGPVSVYAESKLRGEQAIQATFDRFLILRTAWMYSLRASSFLTKVLSWSEKSAEISVVDDQISNPTWARAMAEMTTLMLARLESQAWPASLMGIYHLAGDGYTSRYEWAKAIIEIANQHQVKVNPAKSEDFHTPARRPRFSALDCSKFYQAFDLRLPSWQACLRLSMKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XFA0</accession>
    <name>A0A0P6XFA0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_06010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78879">
        <property type="protein sequence ID" value="KPL78879"/>
        <property type="gene ID" value="ADN00_06010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="253" mass="26700" checksum="FCF430B4115F7502" modified="2016-01-20" version="1">MDFKGKTVIVTGGSRGIGAAISYMFAANGANVMVDYLPVEKDIEGLKQLEQEVHNIGGVVDSFGGDVASPEEMDQLVAKTLERFGGLDILVNSAGFTRPATVESMTPDLWKSGIEVNLSGAFYITQAASRHMISQGSGKIIFIGSAGSITGGGGSVAYSAAKAGINGMVRALSKELAPKGINVNAVLPALIETDLLRDKEPDVEKRNKYIQRIPIGRFGTPEDVAYMVLFLASEYAGFISGQNIIVDGGSTYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XFZ2</accession>
    <name>A0A0P6XFZ2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_06625</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000017">
        <property type="protein sequence ID" value="KPL78590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062192.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000017.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78590">
        <property type="protein sequence ID" value="KPL78590"/>
        <property type="gene ID" value="ADN00_06625"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004155">
        <property type="entry name" value="PBS_lyase_HEAT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00567">
        <property type="entry name" value="EZ_HEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="254" mass="27776" checksum="845BC0E4ABFF44D9" modified="2016-01-20" version="1">MSLHLFFSPPNVQKLRQKSDRKALARAMNYTHGFGIRYPAARALAELADASCLNAFEQAILSGDLQMQQIAAQGLGASGSPQAVPVLLNALAQDCRPRLQAALSRLEDPQTSAKEQLAAWIGDIEENFTLRLLSAEAFIDDPERANNESERPEAAFYLLGTLKKEPARIRAHFLELLTANAKDTSDEVIRQRAQHILSQAQLEATRLAAAILRALGQLHAAGAAEVIRARLTDPDETVRQQAALTLQKLGQPLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XG30</accession>
    <name>A0A0P6XG30_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_04620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061785.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79144">
        <property type="protein sequence ID" value="KPL79144"/>
        <property type="gene ID" value="ADN00_04620"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="252" mass="28280" checksum="05BCD22CE49B366B" modified="2016-01-20" version="1">MNNTFLSTRLTAGAQVTPVENGWRLSIPPGAAGAYRWAQLDDYMDLPRKAFRHVAPLALSLRARVSAQGLPGTWGFGLWNDPFSMGLGVGGARRRLPALPQTAWFFHASDDNYLSLRDDLPANGMLMGVFQAAQLPAWSLLPAAPLLAGLVLPPLARRMRRAARWLVKEDSARLELDFTAWHEYRLEWRAEGVRFAVDGEMRFETRLSPRGRMGLVLWVDNQFAAFRPDGQVRLGTQANPVEAWLEITNVEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XG97</accession>
    <name>A0A0P6XG97_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_04920</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061838.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04920"/>
    <dbReference type="EnsemblBacteria" id="KPL79190">
        <property type="protein sequence ID" value="KPL79190"/>
        <property type="gene ID" value="ADN00_04920"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="42"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="96"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="575"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="195"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="772" mass="85948" checksum="FD0A736D2D69AC87" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGG0</accession>
    <name>A0A0P6XGG0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_18720</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18720"/>
    <dbReference type="EnsemblBacteria" id="KPL70173">
        <property type="protein sequence ID" value="KPL70173"/>
        <property type="gene ID" value="ADN00_18720"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3053"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="156"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="201"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="241"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="307"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="333"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="361"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="392"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="448"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="478" mass="53329" checksum="6E55AEEEC45C8893" modified="2016-01-20" version="1">MLLFLTLLVGFTFIFPRWADWSQNSRLNLTLAIVDHHSLSIDPYFGNTGDYAKFEGHYYSDKAPGPSFLGVPVYAAFRPILRSAPIQALLLKVSQTSAFQNTLNEEGSGLGTEKVEYFVALMVVAFFITCVPSALLGVFLFDFLTLLGLNRSWSLVVVLTFAFATNAFAFSSVFFSHQLVAFCLFTAFYLAFRIHRGLGHPAWVILSGFLLGLAVISEYPSALIALGIFVYTLYVLKKSRWLVGFVAAGVPPGALMMAYNWAIFRTPLPVGYEYSELYTDVHSTGFLSITYPHPEALWGLTFGSFRGLFFSAPVLLLGVAGFIVWWKKKQFRAEWLVSLWAVLSFYLFYASSVMWNGGYAVGPRYLVPMLPFLTLAAGIFAEQFGAKTWAKIVYALLAVLSLLNIWAQTFGGQTFPDWTLNPLFNYSIPNLLAGNVARNWGMVLGLRGITSILPLFLIIALGTGLLFYPLRKRDRRTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGV2</accession>
    <name>A0A0P6XGV2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rplU</name>
        <name evidence="6" type="ORF">ADN00_03575</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">This protein binds to 23S rRNA in the presence of protein L20.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit. Contacts protein L20.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the bacterial ribosomal protein bL21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061593.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03575"/>
    <dbReference type="EnsemblBacteria" id="KPL78983">
        <property type="protein sequence ID" value="KPL78983"/>
        <property type="gene ID" value="ADN00_03575"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.66"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01363">
        <property type="entry name" value="Ribosomal_L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036164">
        <property type="entry name" value="L21-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028909">
        <property type="entry name" value="L21p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001787">
        <property type="entry name" value="Ribosomal_L21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018258">
        <property type="entry name" value="Ribosomal_L21_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21349">
        <property type="entry name" value="PTHR21349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00829">
        <property type="entry name" value="Ribosomal_L21p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141091">
        <property type="entry name" value="SSF141091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00061">
        <property type="entry name" value="L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01169">
        <property type="entry name" value="RIBOSOMAL_L21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL78983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="105" mass="11769" checksum="6CB96421714AC651" modified="2016-01-20" version="1">MKFAIVESGGKQFRAVEGKTIDVDRLSVEAGDKLTLDTVLLYVNEDRVAVGTPVVSGAKVSATVVDHVKGPKLIVFRYRPKKRRRVKTGHRQQYTRLLIDSIDME</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGZ6</accession>
    <name>A0A0P6XGZ6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Robl_LC7 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_04015</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061675.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04015"/>
    <dbReference type="EnsemblBacteria" id="KPL79056">
        <property type="protein sequence ID" value="KPL79056"/>
        <property type="gene ID" value="ADN00_04015"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032008">
        <property type="term" value="P:positive regulation of TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037587">
        <property type="entry name" value="LAMTOR2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004942">
        <property type="entry name" value="Roadblock/LAMTOR2_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13323">
        <property type="entry name" value="PTHR13323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03259">
        <property type="entry name" value="Robl_LC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00960">
        <property type="entry name" value="Robl_LC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Robl_LC7" evidence="1">
        <location>
            <begin position="3"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="116" mass="12467" checksum="EF64DDFFC46D1768" modified="2016-01-20" version="1">MMVERLRELQASSPDIEASAIVSVDGLTIASALPQGVEEDRVSAMSAAMLSLGERIANELGRGSLDQVYIKGEKGYVVLMSVGEEAVLTALAREQAKLGLLFLDMRRAAEDLTKMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XHF2</accession>
    <name>A0A0P6XHF2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_13590</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063569.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000032.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13590"/>
    <dbReference type="EnsemblBacteria" id="KPL74332">
        <property type="protein sequence ID" value="KPL74332"/>
        <property type="gene ID" value="ADN00_13590"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1294"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051304">
        <property type="term" value="P:chromosome separation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01804">
        <property type="entry name" value="ScpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005234">
        <property type="entry name" value="ScpB_csome_segregation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34298">
        <property type="entry name" value="PTHR34298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04079">
        <property type="entry name" value="SMC_ScpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF019345">
        <property type="entry name" value="ScpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00281">
        <property type="entry name" value="TIGR00281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1" id="KW-0132">Cell division</keyword>
    <keyword evidence="2" id="KW-0159">Chromosome partition</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="36"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL74332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="192" mass="20837" checksum="1FA2675D1455E969" modified="2016-01-20" version="1">MSEQAQYSHLSQSDIRNAIEALLYVAAGPVSPGQLAETLAIKVKEAEEQLKALEVEYQAQRGLRLQWHAGRVQITTAPEYADLVEKFLGLDATQKLSRAALETLAIIAYRQPVTRPGVDAIRGVNSDGVMRSLLSKGLVEEVGRADGPGRPILYGTTADFLQYFGLGSLGELPPFEEETAEETPKGNGLLKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XHG3</accession>
    <name>A0A0P6XHG3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">UDP-N-acetylglucosamine 1-carboxyvinyltransferase</fullName>
            <ecNumber evidence="7">2.5.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Enoylpyruvate transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">UDP-N-acetylglucosamine enolpyruvyl transferase</fullName>
            <shortName evidence="7">EPT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">murA</name>
        <name evidence="9" type="ORF">ADN00_13700</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Cell wall formation. Adds enolpyruvyl to UDP-N-acetylglucosamine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>phosphoenolpyruvate + UDP-N-acetyl-alpha-D-glucosamine = phosphate + UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine</text>
            <dbReference type="Rhea" id="RHEA:18681"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:68483"/>
            <dbReference type="EC" id="2.5.1.7"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the EPSP synthase family. MurA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.7" evidence="7"/>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063590.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000032.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13700"/>
    <dbReference type="EnsemblBacteria" id="KPL74350">
        <property type="protein sequence ID" value="KPL74350"/>
        <property type="gene ID" value="ADN00_13700"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1316"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008760">
        <property type="term" value="F:UDP-N-acetylglucosamine 1-carboxyvinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019277">
        <property type="term" value="P:UDP-N-acetylgalactosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01555">
        <property type="entry name" value="UdpNAET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.65.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00111">
        <property type="entry name" value="MurA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001986">
        <property type="entry name" value="Enolpyruvate_Tfrase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036968">
        <property type="entry name" value="Enolpyruvate_Tfrase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013792">
        <property type="entry name" value="RNA3'P_cycl/enolpyr_Trfase_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005750">
        <property type="entry name" value="UDP_GlcNAc_COvinyl_MurA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00275">
        <property type="entry name" value="EPSP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55205">
        <property type="entry name" value="SSF55205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01072">
        <property type="entry name" value="murA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1 7" id="KW-0132">Cell division</keyword>
    <keyword evidence="3 7" id="KW-0133">Cell shape</keyword>
    <keyword evidence="6 7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="EPSP_synthase" evidence="8">
        <location>
            <begin position="7"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphoenolpyruvate binding" evidence="7">
        <location>
            <begin position="22"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="117"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="312"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="334"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL74350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="427" mass="46510" checksum="E3D9281B309A9BBE" modified="2016-01-20" version="1">MEKFIIEGSQPLSGEVTPAGNKNAALPLLSACMLTDEPIILKNVPDILDVNAMRSLLESLGVSIQNLDQHTWQIQAKEIRPADLDPDMCRRIRASILLAGPMTARMGELQLPPPGGDVIGRRRVDTHILALEKLGAQVHYDRSFIFKANGLKGADILLDEASVTATENAITAAVTAKGTTTLRNCASEPHIQELCHFLNGLGAKIENIGSNTLHITGVDRLHGGEFTIGPDYLEVVSFVGAAVVTRGQIRIRNAGVRYLDMIRLVMKRLGVHWIEEGEDILIPSDQKLEVEPDLGGAIPEISVMPWPAFPTDLMSIAIVIATQSKGSVLFHDWMYPSRMFFTDKLVGMGAHIVLCDPHRCIVQGPSRLYGEKMESPDIRAGMALLLAALSAEGKSIIRNVGQIDRGYEKVDQKLAALGAKIERLTQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XI51</accession>
    <name>A0A0P6XI51_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Transketolase</fullName>
            <ecNumber evidence="3 8">2.2.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ADN00_02185</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the transfer of a two-carbon ketol group from a ketose donor to an aldose acceptor, via a covalent intermediate with the cofactor thiamine pyrophosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = aldehydo-D-ribose 5-phosphate + D-xylulose 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:10508"/>
            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="2.2.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="8">
            <name>Ca(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
        </cofactor>
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <cofactor evidence="8">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <text evidence="8">Binds 1 Mg(2+) ion per subunit. Can also utilize other divalent metal cations, such as Ca(2+), Mn(2+) and Co(2+).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
        <text evidence="8">Binds 1 thiamine pyrophosphate per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 8">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the transketolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.1" evidence="3 8"/>
    <dbReference type="EMBL" id="LGCL01000009">
        <property type="protein sequence ID" value="KPL79793.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02185"/>
    <dbReference type="EnsemblBacteria" id="KPL79793">
        <property type="protein sequence ID" value="KPL79793"/>
        <property type="gene ID" value="ADN00_02185"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2759"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004802">
        <property type="term" value="F:transketolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02012">
        <property type="entry name" value="TPP_TK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005478">
        <property type="entry name" value="Transketolase_bac-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020826">
        <property type="entry name" value="Transketolase_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033247">
        <property type="entry name" value="Transketolase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005474">
        <property type="entry name" value="Transketolase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43522">
        <property type="entry name" value="PTHR43522"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00456">
        <property type="entry name" value="Transketolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00232">
        <property type="entry name" value="tktlase_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00801">
        <property type="entry name" value="TRANSKETOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00802">
        <property type="entry name" value="TRANSKETOLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0106">Calcium</keyword>
    <keyword evidence="6 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 8" id="KW-0786">Thiamine pyrophosphate</keyword>
    <keyword evidence="4 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TRANSKETOLASE_1" evidence="9">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL79793.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="668" mass="72877" checksum="0C5A8CD7FCAE1F80" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XJD4</accession>
    <name>A0A0P6XJD4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PNP_UDP_1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_16720</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064193.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16720"/>
    <dbReference type="EnsemblBacteria" id="KPL71352">
        <property type="protein sequence ID" value="KPL71352"/>
        <property type="gene ID" value="ADN00_16720"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.402"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="SSF53167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNP_UDP_1" evidence="1">
        <location>
            <begin position="33"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL71352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="254" mass="27696" checksum="E2E4A5FEFA6D33AC" modified="2016-01-20" version="1">MPSNAPILEFDPAPRAILEPQPFPPTQPIPNRAVLCFFAEVLQHLIDEGRLQPAGALKSEIGLSPYYTLEINNQSILVTHPGVGAPLAAGFLEELIALGVNQFVACGGAGVLNARTHAGHAFVINSAVRDEGVSYHYLPAAREVQPSPRVTAALQASLEEHKVPYELVKTWTTDAIYRETATKRDQRVAEGCEVVEMEAAAFFAVAQFRGVEFGQLLYGGDLVVAEGWDSRAWDQRQDSRSALFWLAVDACTRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKK1</accession>
    <name>A0A0P6XKK1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADH-quinone oxidoreductase subunit B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_16395</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16395"/>
    <dbReference type="EnsemblBacteria" id="KPL72056">
        <property type="protein sequence ID" value="KPL72056"/>
        <property type="gene ID" value="ADN00_16395"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3721"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006137">
        <property type="entry name" value="NADH_UbQ_OxRdtase-like_20kDa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006138">
        <property type="entry name" value="NADH_UQ_OxRdtase_20Kd_su"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01058">
        <property type="entry name" value="Oxidored_q6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01150">
        <property type="entry name" value="COMPLEX1_20K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidored_q6" evidence="1">
        <location>
            <begin position="27"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="157" mass="17065" checksum="F6A91B15C5D42A45" modified="2016-01-20" version="1">MIGLFQHLIKISRRRSPWIYRINAGSCNGCDIEVAPCFSPRYDGEQIGALLQGSPKHADILLISGPVTLRTRDMVKEIYEQVPAPKAVIALGSCPASGNVFSGSPTIIGNLESLIPVDLYVPGCPPRPQAILEAIQKAAHLLENGETHSQQEEDQHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKR2</accession>
    <name>A0A0P6XKR2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glucose-1-phosphate adenylyltransferase</fullName>
            <ecNumber evidence="9">2.7.7.27</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ADP-glucose pyrophosphorylase</fullName>
            <shortName evidence="9">ADPGlc PPase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">ADP-glucose synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">glgC</name>
        <name evidence="11" type="ORF">ADN00_15185</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in the biosynthesis of ADP-glucose, a building block required for the elongation reactions to produce glycogen. Catalyzes the reaction between ATP and alpha-D-glucose 1-phosphate (G1P) to produce pyrophosphate and ADP-Glc.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>alpha-D-glucose 1-phosphate + ATP + H(+) = ADP-alpha-D-glucose + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:12120"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57498"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="2.7.7.27"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="9">Glycan biosynthesis; glycogen biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the bacterial/plant glucose-1-phosphate adenylyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.27" evidence="9"/>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063885.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15185"/>
    <dbReference type="EnsemblBacteria" id="KPL72175">
        <property type="protein sequence ID" value="KPL72175"/>
        <property type="gene ID" value="ADN00_15185"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.739"/>
    <dbReference type="UniPathway" id="UPA00164"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008878">
        <property type="term" value="F:glucose-1-phosphate adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005978">
        <property type="term" value="P:glycogen biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00624">
        <property type="entry name" value="GlgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011831">
        <property type="entry name" value="ADP-Glc_PPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005836">
        <property type="entry name" value="ADP_Glu_pyroP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023049">
        <property type="entry name" value="GlgC_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43523">
        <property type="entry name" value="PTHR43523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00808">
        <property type="entry name" value="ADP_GLC_PYROPHOSPH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00809">
        <property type="entry name" value="ADP_GLC_PYROPHOSPH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="7 9" id="KW-0320">Glycogen biosynthesis</keyword>
    <keyword evidence="2 9" id="KW-0321">Glycogen metabolism</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="10">
        <location>
            <begin position="5"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Alpha-D-glucose 1-phosphate binding" evidence="9">
        <location>
            <begin position="177"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>alpha-D-glucose 1-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
        </ligand>
    </feature>
    <feature type="site" description="Could play a key role in the communication between the regulatory and the substrate sites" evidence="9">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <feature type="site" description="Could play a key role in the communication between the regulatory and the substrate sites" evidence="9">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL72175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="418" mass="46205" checksum="5C5C2F152A5DD8E3" modified="2016-01-20" version="1">MKTRAVILAGGEGTRLGVLTAKRTKPAVTFAGKYRIIDFALSNCVNSNIFDVMIVAQYRPHSLIEHIGSGAPWDLARDFTGGVRIYTPYRAPASGWFSGTADAVQQNYSFIKHSNPDLILILSGDHIYTMDYDAMIQFHIAHQADLTLASISVPIEEASRFGIVGLGDDNRVTSFVEKPKVPPSNRANMGVYVFNQYVLDKLLWDDHLKSESSHDFGKDIIPLMIQKGMRVFAYPYSGYWMDVGTIQSYWKAHMDLLEPYPSLNLYNRSWVIHTRSEERPPANIQSGAVIEDSLISDGCVIESGVKITHSVLSPGVYVQSGSVISHSILLTDCTVQRDVTISHSVIDKRAFLHAGCQVGVGVNPDNLITTVGKNSVIPPRYVLEPGVVIGTDVIPSDYPKNVVKSGEFIQTRRLPHEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKW7</accession>
    <name>A0A0P6XKW7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltransf_11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061236.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01740"/>
    <dbReference type="EnsemblBacteria" id="KPL80589">
        <property type="protein sequence ID" value="KPL80589"/>
        <property type="gene ID" value="ADN00_01740"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="43"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="245" mass="27619" checksum="BC63A96D678FAC2C" modified="2016-01-20" version="1">MGEQHSQKAALRGEPSYVWRAGQERRLTMILDAAGERAQGRVLENGCGVGAYLRRLAERASLAAGLEVEFERAKEARALGLNTLCAVGETLPFAAEEFDLVLSHEVIEHVNDDRQVIREIVRVLKPGGRLTLFCPNRGYPFETHGIYWRGRYHFGNIPLVNYLPRAWRDRLAPHVNVYTTRDLQALFAGLPVKVVQRTVIFGAYDNIIARRPALGKALRAVLQFLEKTPLKHLGLSHFWVVEKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKX5</accession>
    <name>A0A0P6XKX5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HAMP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_15845</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064005.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15845"/>
    <dbReference type="EnsemblBacteria" id="KPL72285">
        <property type="protein sequence ID" value="KPL72285"/>
        <property type="gene ID" value="ADN00_15845"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="260"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="2">
        <location>
            <begin position="285"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL72285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="1081" mass="119739" checksum="38FBBF68B20AAF07" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XL78</accession>
    <name>A0A0P6XL78_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DinB_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10395</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062933.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10395"/>
    <dbReference type="EnsemblBacteria" id="KPL76980">
        <property type="protein sequence ID" value="KPL76980"/>
        <property type="gene ID" value="ADN00_10395"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024775">
        <property type="entry name" value="DinB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12867">
        <property type="entry name" value="DinB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DinB_2" evidence="1">
        <location>
            <begin position="21"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="163" mass="17833" checksum="3CD34DDB245F05CA" modified="2016-01-20" version="1">MAYPDAKHLAQSFHLTYWVIRQQVEGLTHADSLIQPPVRGNCLNWVLGHILTGRCAVLALLGEPPVLTADQMALYETGSAPITGDDGAVALEALLANLDESQQMIFSALRATPQERLDYLLEDGENGQSSVGEEIASLAWHETYHVGQMELLRQLAGKNDQVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XM08</accession>
    <name>A0A0P6XM08_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Macrolide ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_09370</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062774.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77364">
        <property type="protein sequence ID" value="KPL77364"/>
        <property type="gene ID" value="ADN00_09370"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="5"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="235"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="41"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL77364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="259" mass="28167" checksum="9B476DAA9DD3FAE6" modified="2016-01-20" version="1">MNPIIETVEIKKIYGMGDVQVAALDGLSIRILPGEFVAIMGPSGSGKSTLMNILACLDHPSEGQYYLDGKDVSGLSRRELAEIRNQKLGFVFQSYNLLPRLSALENVILPIMYQHHSSMPPEERLERGKAALDVVGLANRAHHLPKELSGGQQQRVAIARALINDPVLILADEPTGNLDSKSSVEIIDLLNGLNERGRTIVMVTHEPDIASYTKRILHIRDGKLEFDHLNGHSRSKLTKEAGAGSQAGAPKTELLGGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-04-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XNF3</accession>
    <name>A0A0P6XNF3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Response regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_14525</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000035">
        <property type="protein sequence ID" value="KPL73556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063754.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000035.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL73556">
        <property type="protein sequence ID" value="KPL73556"/>
        <property type="gene ID" value="ADN00_14525"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="4"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL73556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="134" mass="14906" checksum="8FC3C1596AC6CF07" modified="2016-01-20" version="1">MKETVWMVDDDADVREALRMLLTLLGYDVVEFKEAREVAAAIQTGQKPKILLLDINLPGVSGVQFLPVLRGLPGWKYITIIMVSAESAGESVELAIRQGADGYVFKPVTYDELRMAIQNAQGRRKIKTGELDLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XNR9</accession>
    <name>A0A0P6XNR9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Pvc16_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062847.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09940"/>
    <dbReference type="EnsemblBacteria" id="KPL76910">
        <property type="protein sequence ID" value="KPL76910"/>
        <property type="gene ID" value="ADN00_09940"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025351">
        <property type="entry name" value="Pvc16_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14065">
        <property type="entry name" value="Pvc16_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pvc16_N" evidence="1">
        <location>
            <begin position="4"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="284" mass="32414" checksum="1870FC68667E0B2F" modified="2016-01-20" version="1">MLSDVDEVLRKLLIREIDIQGNEVDIQFDQPKREWSSRLSKPTINLFLFDLRENLRLRGAEQYRTITRPDGMAEIRRNPVRMDLRYLMTAWVKEAEDEHLLLASALTGLLRNPFLPEDLLTPRLQNQPTPIPLDVATFPPEPGPMDKFSEIWGVLDNELRPGILVTVTVAIDPYSPMVYPRVRSLETRFVQDSAIQQPAAPVVTRAPSKTYHSVGGRIKSEKYTPSSLSMVLVETHSAVEISEDGGYTLHKVMDGEYHLDILFNQKVLKRQKIVVPSPSYDIQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XNT7</accession>
    <name>A0A0P6XNT7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_14425</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000034">
        <property type="protein sequence ID" value="KPL73757.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063729.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000034.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL73757">
        <property type="protein sequence ID" value="KPL73757"/>
        <property type="gene ID" value="ADN00_14425"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022791">
        <property type="entry name" value="L-PG_synthase/AglD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03706">
        <property type="entry name" value="LPG_synthase_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00374">
        <property type="entry name" value="TIGR00374"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="131"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="195"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="271"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL73757.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="319" mass="35563" checksum="91FAFE4E6CFD612B" modified="2016-01-20" version="1">MEENRHRTGNQWLRITGTLLSLALLAYLLWQQDWQELWRQVRGVSLWVWLGCFGLYFSGQVFNALRWYILLRSKQVEITFLECLKLILSGAFASNFLPSTVGGDVLRVVGSQPFTGSYTLSLASVLLDRGLNVFAMLATLPFSFFTFTAPNVHLDLKQQLSSALALGLPALRQKLGKALKKFKDALLLWFNQPRVLAAALIISWLSVLVIFVGNIILAHHLGMPVKFYQVVGVNAITYLLTLLPITLNGYGVREVLITTLYVALGGSLEQAASLAVITRFFMLLETLPGSLWIGSYLSLIRLSKEDKASEPRLDGENGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XNZ9</accession>
    <name>A0A0P6XNZ9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_10415</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062937.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10415"/>
    <dbReference type="EnsemblBacteria" id="KPL76983">
        <property type="protein sequence ID" value="KPL76983"/>
        <property type="gene ID" value="ADN00_10415"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005079">
        <property type="entry name" value="Peptidase_C45"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03417">
        <property type="entry name" value="AAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="358" mass="40272" checksum="50937425F6604C9E" modified="2016-01-20" version="1">MKEKMIPLISIYGSHRQMGNQIGEACRQQVAHSIENARTLLSDAYNDLQLTWGGAQIQSRKYIPFAEERYPQYVEELHGIAEGANVSFDDVAVVNAMEAVTTDALHLMKCTSLAVNQSCTANDNVLVAHNEDWVPEDEDDVFLVHAQPADEPPFLAMTYGCLLPNIGFNAYGIAQCCDSVYTEDCRIGIPRIIVSRAVLAAKRPSDAIRHMLAPKRAAGYNHLLVHESGEIYSVEVSARQFALLYGEDGYMVHTNHYVDPEMKKIESEPDELISTRVRYWRASRLLTQSRRHTVKTLQEILRDHLNSPDAICNHDTAGDPLDREKTITSLVMDLTTRQMHAAWGNPCENTYHTFQLNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XP86</accession>
    <name>A0A0P6XP86_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein translocase subunit SecE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">secE</name>
        <name evidence="8" type="ORF">ADN00_17675</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the SecE/SEC61-gamma family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000043">
        <property type="protein sequence ID" value="KPL70878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17675"/>
    <dbReference type="EnsemblBacteria" id="KPL70878">
        <property type="protein sequence ID" value="KPL70878"/>
        <property type="gene ID" value="ADN00_17675"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043952">
        <property type="term" value="P:protein transport by the Sec complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00422">
        <property type="entry name" value="SecE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005807">
        <property type="entry name" value="SecE_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038379">
        <property type="entry name" value="SecE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001901">
        <property type="entry name" value="Translocase_SecE/Sec61-g"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33910">
        <property type="entry name" value="PTHR33910"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00584">
        <property type="entry name" value="SecE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00964">
        <property type="entry name" value="secE_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0811">Translocation</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="41"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL70878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="69" mass="7928" checksum="A4E6C66C4F3DEF11" modified="2016-01-20" version="1">MSDKNETKKPNPIAKWWRETVGELRKVTWPTTHDAWRLTKIVLLTMVVMSAILGVLDFVFSKLVGLIFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XPS2</accession>
    <name>A0A0P6XPS2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_05295</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061931.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78671">
        <property type="protein sequence ID" value="KPL78671"/>
        <property type="gene ID" value="ADN00_05295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="321" mass="34255" checksum="EE9011D6EF6B78DF" modified="2016-01-20" version="1">MEESPLSKLSLEQTAVLNDDQKAIFCALDERDQDFFAQTFKPADLPKALDRKGEILNRHQADRARLEKIRVSLAQAAAENPAGEDGAEDVLTALAGAAGIGAAATMVATDNTAFWQGVKPSDLVDPLRTEFTNERTRVSVSGDADALVVNVLLVTDGFQAVPALTVHLSDVNNGTQVKVSDLTSHGILQTIKDGGKKLLDIAADGLELLAKKKLSMAGPGDVISKAGEVLDEGSELAKVAGNLKLNERAWKVIKQTAEAVEASYLSEKQRQLEARIALEGAWDRYTNCPTCGVSFDAGETSCHVCGTARPPAPQQPDPRQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XPU5</accession>
    <name>A0A0P6XPU5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_05535</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78708.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05535"/>
    <dbReference type="EnsemblBacteria" id="KPL78708">
        <property type="protein sequence ID" value="KPL78708"/>
        <property type="gene ID" value="ADN00_05535"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008982">
        <property type="term" value="F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011608">
        <property type="entry name" value="PRD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036634">
        <property type="entry name" value="PRD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036095">
        <property type="entry name" value="PTS_EIIB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013011">
        <property type="entry name" value="PTS_EIIB_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00874">
        <property type="entry name" value="PRD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52794">
        <property type="entry name" value="SSF52794"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63520">
        <property type="entry name" value="SSF63520"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51372">
        <property type="entry name" value="PRD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51099">
        <property type="entry name" value="PTS_EIIB_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PRD" evidence="3">
        <location>
            <begin position="326"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="PTS EIIB type-2" evidence="2">
        <location>
            <begin position="438"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL78708.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="523" mass="58738" checksum="11BACA1C74F1F43C" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQ36</accession>
    <name>A0A0P6XQ36_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Putative pyruvate, phosphate dikinase regulatory protein</fullName>
            <shortName evidence="5">PPDK regulatory protein</shortName>
            <ecNumber evidence="5">2.7.11.32</ecNumber>
            <ecNumber evidence="5">2.7.4.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_09105</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Bifunctional serine/threonine kinase and phosphorylase involved in the regulation of the pyruvate, phosphate dikinase (PPDK) by catalyzing its phosphorylation/dephosphorylation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ADP + N(tele)-phospho-L-histidyl/L-threonyl-[pyruvate, phosphate dikinase] = AMP + H(+) + N(tele)-phospho-L-histidyl/O-phospho-L-threonyl-[pyruvate, phosphate dikinase]</text>
            <dbReference type="Rhea" id="RHEA:43692"/>
            <dbReference type="Rhea" id="RHEA-COMP:10650"/>
            <dbReference type="Rhea" id="RHEA-COMP:10651"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:83586"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.32"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>H(+) + N(tele)-phospho-L-histidyl/O-phospho-L-threonyl-[pyruvate, phosphate dikinase] + phosphate = diphosphate + N(tele)-phospho-L-histidyl/L-threonyl-[pyruvate, phosphate dikinase]</text>
            <dbReference type="Rhea" id="RHEA:43696"/>
            <dbReference type="Rhea" id="RHEA-COMP:10650"/>
            <dbReference type="Rhea" id="RHEA-COMP:10651"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:83586"/>
            <dbReference type="EC" id="2.7.4.27"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the pyruvate, phosphate/water dikinase regulatory protein family. PDRP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.32" evidence="5"/>
    <dbReference type="EC" id="2.7.4.27" evidence="5"/>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09105"/>
    <dbReference type="EnsemblBacteria" id="KPL77358">
        <property type="protein sequence ID" value="KPL77358"/>
        <property type="gene ID" value="ADN00_09105"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4055"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043531">
        <property type="term" value="F:ADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016776">
        <property type="term" value="F:phosphotransferase activity, phosphate group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006470">
        <property type="term" value="P:protein dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00921">
        <property type="entry name" value="PDRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005177">
        <property type="entry name" value="Kinase-pyrophosphorylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026565">
        <property type="entry name" value="PPDK_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31756">
        <property type="entry name" value="PTHR31756"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03618">
        <property type="entry name" value="Kinase-PPPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="152"/>
            <end position="159"/>
        </location>
        <ligand>
            <name>ADP</name>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL77358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="276" mass="30296" checksum="2E288981DC4642D3" modified="2016-01-20" version="1">MEEQATPSIFIVSGGVGASGEQLIHTMLAQFPDDAVNVVTVGNIRQSEQIDEVLQKALLSDGLIVSTLVDSHLNNHLNREAARLNVASFDLMGPLIQWVSQKTGTEPLGQPGLYRKLHRVYYDRVAAIDFAMAHDDGKNPEDWPQAEAVIVGVSRVGKTPLSLYLAVLGWKVANYPLVPQLAIPSTLFSLEPHRVFGLTIDPHALVNFRLRRQRHIGAPGSSSYTDPVAVYEEIQDALKLFRQNGFTVINMTNKTIELGADEIIHHLSQSSGQTST</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQN4</accession>
    <name>A0A0P6XQN4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_04360</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79101">
        <property type="protein sequence ID" value="KPL79101"/>
        <property type="gene ID" value="ADN00_04360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="67" mass="7781" checksum="445CC7A34F894079" modified="2016-01-20" version="1">MKKEKYENQQTRVYKGIRENYDGVLTGRTTSFPAVSNQEVRKTGEKILKSEKNDIVIIDSCPLQYKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XRA9</accession>
    <name>A0A0P6XRA9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">T2SSF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_15245</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063897.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15245"/>
    <dbReference type="EnsemblBacteria" id="KPL72185">
        <property type="protein sequence ID" value="KPL72185"/>
        <property type="gene ID" value="ADN00_15245"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.751"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018076">
        <property type="entry name" value="T2SS_GspF_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00482">
        <property type="entry name" value="T2SSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="137"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="286"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="T2SSF" evidence="7">
        <location>
            <begin position="174"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL72185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="315" mass="35315" checksum="7512775DBCC9E4D6" modified="2016-01-20" version="1">MLPIIILVVVVVAGAGILVYIGLRNPQTVNERILQDRLEELSQRGEQIDLEKLEMSQPFSERVIYPVAQRFGEIAMKFTPQNARQSIAKRLELAGTSSRLDPTLFLSLQFTAMLIFGGLIFLVFTVGSTQWPIGRKLLVSLLFGLLGFYFPMLWLSSKISRRQKEVWKALPDALDLLTICVEAGLGFDSAMSKVSEKWETELSLAFARVIREVQLGKLRREALRDMADRLGVPEMTSFVAAVIQSEQLGVSLAKVLRIQSDQMRIKRRQRAEEEAHKAPLKMLIPMALLIFPALMVVLLTPAALQLIHSALSGIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XTJ2</accession>
    <name>A0A0P6XTJ2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_11040</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063069.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11040"/>
    <dbReference type="EnsemblBacteria" id="KPL76500">
        <property type="protein sequence ID" value="KPL76500"/>
        <property type="gene ID" value="ADN00_11040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.902"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033138">
        <property type="entry name" value="Cu_oxidase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13508">
        <property type="entry name" value="Acetyltransf_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00079">
        <property type="entry name" value="MULTICOPPER_OXIDASE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="10"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="139" mass="15943" checksum="725902C77520BAA0" modified="2016-01-20" version="1">MEWKKGDFCVSCDPARLSLDVIFEYLSQRSYWGQGRPRELVEKSIQNSLCFGLYLGDEQIGFARTVTDYATMFWLADVFVLEDYRGQGLGVWLVECVVNHPDLQGLRGILATRDAHGLYQKVGFEALENPRSVMRMPKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XU80</accession>
    <name>A0A0P6XU80_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Lactamase_B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062859.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10000"/>
    <dbReference type="EnsemblBacteria" id="KPL76920">
        <property type="protein sequence ID" value="KPL76920"/>
        <property type="gene ID" value="ADN00_10000"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="18"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="223" mass="24270" checksum="33A403D066018EC3" modified="2016-01-20" version="1">MTQEIIILTLPMPFGMGAVNSYLIKNPAGQILIDSGSPRARKALREQLTSAGCEEDRLRLVLLTHGDFDHIGNAAHLRACCGVPLAMHREEACMAERGDMFANRQKPSALVRVLVPFFTGFGRAERFCPDVLLEDGSDLLPYGLDARVVWLPGHSRGSIGVLTANGELFCGDLFENREAPTLNSLLDDATAAQASAARLAGLNIQRVYPGHGQPFTWEELKKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUE7</accession>
    <name>A0A0P6XUE7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_10550</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062962.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77003">
        <property type="protein sequence ID" value="KPL77003"/>
        <property type="gene ID" value="ADN00_10550"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL77003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="189" mass="21446" checksum="3F9E7D9BD0E1B6B0" modified="2016-01-20" version="1">MKNIILGGVPRSGKSLLAQRLCRDLGLSHLSLDSLVSAFSRVFPGLGITHAATSPIETARRLSPFVLEWLRHLEFEGVPFLLEGYHLLPEDLRSLDARRYVVAFIGYPSLKAPEIKLRQVRAFARANDWTRDLSNEELLPIIRRYISESHMLADTCSAERMLFVDTGEFFDDALEEAFEVLSLRAEDTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUJ2</accession>
    <name>A0A0P6XUJ2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_15035</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000036">
        <property type="protein sequence ID" value="KPL73100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063853.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000036.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15035"/>
    <dbReference type="EnsemblBacteria" id="KPL73100">
        <property type="protein sequence ID" value="KPL73100"/>
        <property type="gene ID" value="ADN00_15035"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047560">
        <property type="term" value="F:3-dehydrosphinganine reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006666">
        <property type="term" value="P:3-keto-sphinganine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030148">
        <property type="term" value="P:sphingolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08939">
        <property type="entry name" value="KDSR-like_SDR_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045022">
        <property type="entry name" value="KDSR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL73100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="272" mass="30112" checksum="AFA528BE0AC4E76C" modified="2016-01-20" version="1">MKSFAHQFVMISGGSSGIGLALAEEFARLGANLCILARREEMLAQAATRIQQQFASEQQWVRTISVDIVDRAALQEKLNACMQSMGVPDLVINSAGVAHPGHFENLSYEIFDWMMNVNYMGTVNVCKTVIPGMIQRRSGKIVNISSVAGFLGVYGYTAYSGSKFAVRGFSDALRSEMKLHNIQVQTVFPPDTQTPQLEYENQYKPKITEALSSSAGIMSAEKVAKNIIRGIQKHKPLIIPGFESQLMFFLSNLLGAWMYPIMDLMVKNASKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUK6</accession>
    <name>A0A0P6XUK6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidase M24</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_06375</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062126.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78839">
        <property type="protein sequence ID" value="KPL78839"/>
        <property type="gene ID" value="ADN00_06375"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_NTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001714">
        <property type="entry name" value="Pept_M24_MAP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00599">
        <property type="entry name" value="MAPEPTIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="SSF53092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M24" evidence="1">
        <location>
            <begin position="158"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="391" mass="43443" checksum="CB37BA8D520F4DAC" modified="2016-01-20" version="1">MKYSVNQEKMDQAANYLAQHGIDVWIILTSEGSDPCLPLVTGVRTVGPGAFVLTSSGQRYALCSSIDAQDIEESGLFTEVIKYRENLAQPLQALVAQYAPKKIALNYSQQEHLCDGLTVGRFRWLQETLKDCFSGEWVSSELFLKDLRSIKSPEEIRRIQKAVDITLDIYAEAFSQIRPGLTEKQIGQLFVQAMEKRGVVNGLDKQLSMPMVLKGNIAHRAPSDWATEHGDMLIIDFSVDYEGYVSDIARTAYFLKPGEVEAPAEMKYAFESAYGAISQGFEALKPGKAGYEIDRAARDYLLSRGMPEISHATGHQIGRETHDGGTLLGPLWERYGEAPRGLIAENMVFTLEPTILPSEGPFILVEENVLVTATGAKYLSRRQESLILIQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUX8</accession>
    <name>A0A0P6XUX8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_03740</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061623.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03740"/>
    <dbReference type="EnsemblBacteria" id="KPL79013">
        <property type="protein sequence ID" value="KPL79013"/>
        <property type="gene ID" value="ADN00_03740"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002829">
        <property type="entry name" value="DUF116"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01976">
        <property type="entry name" value="DUF116"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="406" mass="44956" checksum="A675111354B49272" modified="2016-01-20" version="1">MNNNFAYDLRINQQDSLPAHQQISVFTDRWLGYLHAAHTGLLEEYRQFRQSSGLPALSFAESALELTAFCVYLQEHSAEARVFSGLGAAALTALVNLQDRLPWFERSIKALRSRVQYLSTRKSASPSDTPDLDPATLNRLLRWLRAQGQSALAEHFQPWARCFGRRGRQQCQAALNDCLLIAAQFTAFSSEVLGGYTRGAEAFRQSARRDACLRYDAALRGRARAEYHLGLLGTEILNREFRTAFLQASEKLVIVPRCLRARPQGLCKAAPARLGTRCTGCTPHCQVNQISQICRPLGIHVADIPDDQLKFLCRASGQAGSGLGVLGLSCAPTNWLAGWEAQKLGLSAQGLLLDYPACREHWHAQGLPTSTSLLRLKEILKISPKTEPDESSAWVLLPAEQTEMAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUZ4</accession>
    <name>A0A0P6XUZ4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_03890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061653.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79040">
        <property type="protein sequence ID" value="KPL79040"/>
        <property type="gene ID" value="ADN00_03890"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.132"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01547">
        <property type="entry name" value="SBP_bac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133236" evidence="1">
        <location>
            <begin position="29"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="476" mass="52079" checksum="E297E2F044247183" modified="2016-01-20" version="1">MRKPIFAMFALIVVFSMLLAACQPAAPAAEQPAEAAAPAEAPAATEAPAAAPAAGDRVQVRWFVGLGTGQQPEQVAAQEEVVKKFNESQDEIELVIEIVNYDVANDTLATQIAAGNAPDIIGPVGVAGSNAYSGQWLDLDPLVASMNYDLSDFDESAVDFYRVEGEGLIGLPFAVYPYFLYYYKPAFDEAGLAYPPHEWGAKYEDGDDWDMDKLTELAMQLTVDANGNDATEAGFDPANIVQFGYYTQWTDPRGLATMFGASNFVDENGKAMVSDNWREAFNWYYDAIWNKHFYPTDSYINSDLLAAGNAFGSGNVAMVGLHLWCHACSESEDWDIAAIPSYKGEITAKLHADTFRIMKSTKNPEAAFKVLDYLTGEAADELLLVYGGMPARHSLQDSYFATLDEAHPQGVDWEVAKAALNYTDNPSHEANMPNFNKATERIGAFQTLFQSTADLDINAEIDKLVADLQVIFDEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XW20</accession>
    <name>A0A0P6XW20_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_02500</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000011">
        <property type="protein sequence ID" value="KPL79571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061382.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000011.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79571">
        <property type="protein sequence ID" value="KPL79571"/>
        <property type="gene ID" value="ADN00_02500"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133252" evidence="2">
        <location>
            <begin position="27"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="265" mass="28116" checksum="67A6604A3B536225" modified="2016-01-20" version="1">MRRGFTLIAASLPALLLTLLCLPACAPTALPVTGGTPTPFQPYQFTPTAFLPLHPTDTPAPEPPAAQPQPSQRFHGIDFSDTQSWVEIIITPPDETVNRGRPIRMRFKPGAECNFGSQRACVSAYLQPDGSEVIFLSIHSGVGGQAQSYRHAVEGTGINQAGFSLAQTLQNLQNLKGASVGIRQNDVELYQFTLLETARIPASGLSAYFAAPVSQALPVSGFATPPGEAGQPLLVFETCGWHMPGESRADAVSGTTASVYLAVIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XX28</accession>
    <name>A0A0P6XX28_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">MFS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_00725</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. TCR/Tet family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061033.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL81085">
        <property type="protein sequence ID" value="KPL81085"/>
        <property type="gene ID" value="ADN00_00725"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3543"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005829">
        <property type="entry name" value="Sugar_transporter_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001958">
        <property type="entry name" value="Tet-R_TetA/multi-R_MdtG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01035">
        <property type="entry name" value="TCRTETA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00216">
        <property type="entry name" value="SUGAR_TRANSPORT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="111"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="146"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="225"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="262"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="291"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="317"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="351"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="381"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="7">
        <location>
            <begin position="20"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL81085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="418" mass="46263" checksum="1FFE7F2699F406A1" modified="2016-01-20" version="1">MFIQNQIKKIKTVYNDYPRQFWLVMGAFFIDRVGGALIFPFFTLYITKKFGVGLSEAGLLFGVHFVSSIVGTTIGGALADRMGRKGTLIFGLLSSAFSMLLMGFVNNITAFFLVALISGLFASVGDPAGHAMVADLLPEEKRPEGYGIWRVSANLAVVIGPAIGGLLAAYSYLYLFITDAVASTITSIVIFILVKETHKAPEVSKARSESFFSTVKGYGDVFKDGAFLVFMFIQIIVVLVYMQMNTTLGVYLRDHHQITELYFGYILSLNAAMVVLFQFPITRRIRNFPPMIVMTVGTLLYAVGFAMYGFVAVYPLFLLAMVIITIGEMLVSPVGTSIVASFAPEDKRGRYMAVFSYSWTLPNIFGLYLSGLIIDNHDPRILWYIAGILGMFASFGYYLLHLSEKRKTAAAEIPEIRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XY37</accession>
    <name>A0A0P6XY37_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_07345</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062332.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07345"/>
    <dbReference type="EnsemblBacteria" id="KPL78273">
        <property type="protein sequence ID" value="KPL78273"/>
        <property type="gene ID" value="ADN00_07345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018488">
        <property type="entry name" value="cNMP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00889">
        <property type="entry name" value="CNMP_BINDING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="2">
        <location>
            <begin position="14"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="173"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL78273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="386" mass="42438" checksum="E7E2660BDB58138F" modified="2016-01-20" version="1">MTAEIHPIKIIQSAFPGIQDSLAQELVEAGKEIQVAPQTVICREGAVENTFYIILNGEVRVTKLINEAENRLLTHLRPGDFFGEMAIIHNAPRAATVTAVQPTTLLEISSQVFSDLIERSSSMSLAMVRAVSNRLRDNDEMAIEDLRQKTRELAHAYQQLAEQEKARSQFLTTIAHELRTPLMAAAGFLQVVRTGQLQGDSLNSALETISSNLQQIMNLTNDILFLQEMDLILAEFQLTDVTALLHTCVEKLRLPTTKSPITIHFNLPTGLPRVPADPKSLERSLSAVLDNAVKFSPEGGVIEISASFDAQTLSIQITDHGVGIPAEALPHIFDRFFHLDQAGNHLFRGVGLGLSIARQVIEQHHGNIQVQSPLGLGSTFTITLPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XY67</accession>
    <name>A0A0P6XY67_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_00685</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL81079">
        <property type="protein sequence ID" value="KPL81079"/>
        <property type="gene ID" value="ADN00_00685"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL81079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="73" mass="8642" checksum="3CC2CDB9E37C7C9C" modified="2016-01-20" version="1">MTDMNPTSEERDAYHAFLLRLWRTQSQGKTQWRASLESPHTGERQSFASLEQLFAFLSERCEGQPPEDDWRPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y2D8</accession>
    <name>A0A0P6Y2D8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_04310</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061727.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04310"/>
    <dbReference type="EnsemblBacteria" id="KPL79096">
        <property type="protein sequence ID" value="KPL79096"/>
        <property type="gene ID" value="ADN00_04310"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010226">
        <property type="entry name" value="NADH_quinone_OxRdtase_chainI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10849">
        <property type="entry name" value="PTHR10849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13237">
        <property type="entry name" value="Fer4_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="37"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="73"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL79096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="144" mass="16474" checksum="9F689C3322172681" modified="2016-01-20" version="1">MMRIGAMFSEVFGALFNKPRTQPYPVEKIPAPPRYRGKLVYNPETCTGCMLCVKDCPAEALELLVIDRKAKKFVMRYHSDRCVYCSQCVENCRFGCLEMSNDQWELAALNKEPFTIYYGKEEDVRTILEPAAAEQTEEPCTQPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y364</accession>
    <name>A0A0P6Y364_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH arsR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_03180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000014">
        <property type="protein sequence ID" value="KPL79343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061513.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000014.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79343">
        <property type="protein sequence ID" value="KPL79343"/>
        <property type="gene ID" value="ADN00_03180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="9"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="186" mass="21037" checksum="6B38CD47FFDBC04D" modified="2016-01-20" version="1">MDKLSKVEVVIHPLRLQILQTLTRGSLTTQQIADELPQQPKSSIYRHLKILLEAEMVQVVETRVVKGKEERVYALAQAPHINAEDIAHATAEDHRQMFTMYIVSLMSGFSDYLESGKAPDLVNDRVGIGEFILNVTREELDEFSKKLQEALIPLLNNPAGEGRYKHKFALISHPISQLKNGLEEPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y4P9</accession>
    <name>A0A0P6Y4P9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Transgly domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_01795</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000006">
        <property type="protein sequence ID" value="KPL80120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061250.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000006.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01795"/>
    <dbReference type="EnsemblBacteria" id="KPL80120">
        <property type="protein sequence ID" value="KPL80120"/>
        <property type="gene ID" value="ADN00_01795"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3810.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001264">
        <property type="entry name" value="Glyco_trans_51"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023346">
        <property type="entry name" value="Lysozyme-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036950">
        <property type="entry name" value="PBP_transglycosylase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00912">
        <property type="entry name" value="Transgly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53955">
        <property type="entry name" value="SSF53955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="51"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="Transgly" evidence="4">
        <location>
            <begin position="135"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="5">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL80120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="974" mass="103952" checksum="5FFDFDA1D89848F7" modified="2016-01-20" version="1" fragment="single"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y5F9</accession>
    <name>A0A0P6Y5F9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_01410</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061176.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01410"/>
    <dbReference type="EnsemblBacteria" id="KPL80532">
        <property type="protein sequence ID" value="KPL80532"/>
        <property type="gene ID" value="ADN00_01410"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1036"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL80532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="141" mass="16505" checksum="A336AB125BB7AC3D" modified="2016-01-20" version="1">MEEYKFVYPLQVRYGDLDPQWHVNNARFLTFIEQARFAYLVELGIFDGKDFFEVPFIVADIHVAYLAPIHLTQTIEVRMRTGKLGNKSLRFDYLIADSDTGEELARAETVMVAYNYHTRQSMPIKESWRQAILDYEGQTLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y5G5</accession>
    <name>A0A0P6Y5G5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01475</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061187.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01475"/>
    <dbReference type="EnsemblBacteria" id="KPL80541">
        <property type="protein sequence ID" value="KPL80541"/>
        <property type="gene ID" value="ADN00_01475"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021359">
        <property type="entry name" value="DUF2812"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11193">
        <property type="entry name" value="DUF2812"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="120"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="208" mass="24993" checksum="8633EACA115EAFC4" modified="2016-01-20" version="1">MNTQRTEYQLFLSFEKEEAWLEAQSRQGWHLVNVSSGWKYVFEQGQPEERVYKIDFRFFKRQEEMDEYVSLFEDSGWRCVSPQKGSYNYYFYTTRKEGEQTDIFSDQASRAQRYLRYAQYSLLSFIPFLPIYTALYANGAIKIQELGYLTPGLWQMQGMQFWLRFLFETPFVVLRVAGGLLPLLIVLLFVFFSLRFSFQYRKLLRQQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y635</accession>
    <name>A0A0P6Y635_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Small ribosomal subunit biogenesis GTPase RsgA</fullName>
            <ecNumber evidence="7">3.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rsgA</name>
        <name evidence="10" type="ORF">ADN00_10855</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">One of several proteins that assist in the late maturation steps of the functional core of the 30S ribosomal subunit. Helps release RbfA from mature subunits. May play a role in the assembly of ribosomal proteins into the subunit. Circularly permuted GTPase that catalyzes slow GTP hydrolysis, GTPase activity is stimulated by the 30S ribosomal subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer. Associates with 30S ribosomal subunit, binds 16S rRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the TRAFAC class YlqF/YawG GTPase family. RsgA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.-" evidence="7"/>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063018.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10855"/>
    <dbReference type="EnsemblBacteria" id="KPL77049">
        <property type="protein sequence ID" value="KPL77049"/>
        <property type="gene ID" value="ADN00_10855"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01854">
        <property type="entry name" value="YjeQ_EngC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01820">
        <property type="entry name" value="GTPase_RsgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030378">
        <property type="entry name" value="G_CP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004881">
        <property type="entry name" value="Ribosome_biogen_GTPase_RsgA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010914">
        <property type="entry name" value="RsgA_GTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031944">
        <property type="entry name" value="RsgA_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32120">
        <property type="entry name" value="PTHR32120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03193">
        <property type="entry name" value="RsgA_GTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16745">
        <property type="entry name" value="RsgA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00157">
        <property type="entry name" value="TIGR00157"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50936">
        <property type="entry name" value="ENGC_GTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51721">
        <property type="entry name" value="G_CP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="7" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CP-type G" evidence="9">
        <location>
            <begin position="82"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="ENGC_GTPASE" evidence="8">
        <location>
            <begin position="91"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="131"/>
            <end position="134"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="182"/>
            <end position="190"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="264"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="271"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="277"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL77049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="307" mass="34139" checksum="55D71B501138EF90" modified="2016-01-20" version="1">MAHPPRIEGLITRYQSGFYAVRTAQGEALCHLRGRLKKQRAGSDLLAVGDRVEISLQPDGSGMIESIHARERALVRLAPTPRGDYRQVLLANPDQIVLVFACRQPDPHLRMLDRFLVICEKNHLPVVIVANKTDLIAAEEARELFSIYPPLGYRVIFASAQDGEGIEDLREALRGKLSGLVGPSGVGKSSLLNAVQPDLGLAVSDVSDQTSKGRHTTVVRELFPLREGGFVADLPGLRSLALWDTEPEELDGYFPELRELVRHCQFSDCTHQHEPGCAVLQAVEEGRVHPHRYQSYLRLRFGDELDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y6M6</accession>
    <name>A0A0P6Y6M6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">BTAD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_00690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061026.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00690"/>
    <dbReference type="EnsemblBacteria" id="KPL81080">
        <property type="protein sequence ID" value="KPL81080"/>
        <property type="gene ID" value="ADN00_00690"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3534"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041664">
        <property type="entry name" value="AAA_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13191">
        <property type="entry name" value="AAA_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03704">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01043">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BTAD" evidence="1">
        <location>
            <begin position="104"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL81080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="1216" mass="132042" checksum="E238A4A14A469417" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YAA7</accession>
    <name>A0A0P6YAA7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AP_endonuc_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05915</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062044.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78768">
        <property type="protein sequence ID" value="KPL78768"/>
        <property type="gene ID" value="ADN00_05915"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="1">
        <location>
            <begin position="25"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="281" mass="31287" checksum="7DB58A3DCDC1A9A4" modified="2016-01-20" version="1">MLPIGIHLSYWQVSWSDDLEPLIFKAKKAGFDVAEFPLLNPLDLDYERLRNALVAEGMLASCGTGLGPTTDISSPDPKIRQAGLDHLQACFEGAEKLGSPILGGVTYAAWGMFPDQGFRQRRDFCIQSLRLAGKMAADHGVTLCLEVLNRFEGYIINTAEQGIQLLNEIGHPNIKLHLDTFHMNIEEDNIFEAIMKAGNYLGHFHCVENNRKIPGEGHIPWLEVQKALKLIRYQGYLVTESFVNPAGEVGRGLSIWRPLADDLDQAAHRAAEFLKHEVANV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YB13</accession>
    <name>A0A0P6YB13_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Heterodisulfide reductase subunit F</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_04445</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="4">Binds 1 [2Fe-2S] cluster per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PyrK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061749.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04445"/>
    <dbReference type="EnsemblBacteria" id="KPL79116">
        <property type="protein sequence ID" value="KPL79116"/>
        <property type="gene ID" value="ADN00_04445"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.245"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006221">
        <property type="term" value="P:pyrimidine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.240.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012165">
        <property type="entry name" value="Cyt_c3_hydrogenase_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037117">
        <property type="entry name" value="Dihydroorotate_DH_ele_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019480">
        <property type="entry name" value="Dihydroorotate_DH_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10418">
        <property type="entry name" value="DHODB_Fe-S_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006816">
        <property type="entry name" value="Cyc3_hyd_g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="5">
        <location>
            <begin position="9"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="251"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="256"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="267"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR006816-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL79116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="285" mass="31494" checksum="FCC5C90BFB6B4084" modified="2016-01-20" version="1">MHNNGNNPYEPMPMRIARAYYESNDRSLKTFELVFERDADCKQFFAHYNPGQFCQLSIFGKGEAPFGIASAAWEGDFVRFTVQKMGTFTQAIHRMKAGDPIGMRGPLGNGFPLDDWGGKNLVIIGGGCAFSTLYALTKHIQHPDHRGGFNELCVIYGARNSGLCMYKSDIQSWYGRDDLEIHQAVDVPEEGWMHHIGYVPDVVKEVAPSPDNAVAVVCGPPIMTKYTLPVLTDLGFAPETIFTSLEKRMKCGVGKCGRCNIGPEYICKDGPVFSLAELQALPADL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YB43</accession>
    <name>A0A0P6YB43_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_04615</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79143">
        <property type="protein sequence ID" value="KPL79143"/>
        <property type="gene ID" value="ADN00_04615"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="79" mass="8284" checksum="F53616590F0697E5" modified="2016-01-20" version="1">MSNLVLKGCFLHPSLISSGKGRATSAGMGFSQQEFGQNGGLAALDVPRSTAGISISPRIRSQRHPTPAGWVVGEFFTLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YB90</accession>
    <name>A0A0P6YB90_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">DNA polymerase I</fullName>
            <ecNumber evidence="2 11">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">polA</name>
        <name evidence="15" type="ORF">ADN00_04915</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10 11">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 11">Belongs to the DNA polymerase type-A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="2 11"/>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061837.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04915"/>
    <dbReference type="EnsemblBacteria" id="KPL79189">
        <property type="protein sequence ID" value="KPL79189"/>
        <property type="gene ID" value="ADN00_04915"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.350"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006261">
        <property type="term" value="P:DNA-templated DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09898">
        <property type="entry name" value="H3TH_53EXO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002562">
        <property type="entry name" value="3'-5'_exonuclease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020046">
        <property type="entry name" value="5-3_exonucl_a-hlix_arch_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002421">
        <property type="entry name" value="5-3_exonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036279">
        <property type="entry name" value="5-3_exonuclease_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019760">
        <property type="entry name" value="DNA-dir_DNA_pol_A_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001098">
        <property type="entry name" value="DNA-dir_DNA_pol_A_palm_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043502">
        <property type="entry name" value="DNA/RNA_pol_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020045">
        <property type="entry name" value="DNA_polI_H3TH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018320">
        <property type="entry name" value="DNA_polymerase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002298">
        <property type="entry name" value="DNA_polymerase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008918">
        <property type="entry name" value="HhH2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10133">
        <property type="entry name" value="PTHR10133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01367">
        <property type="entry name" value="5_3_exonuc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02739">
        <property type="entry name" value="5_3_exonuc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00476">
        <property type="entry name" value="DNA_pol_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01612">
        <property type="entry name" value="DNA_pol_A_exo1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00868">
        <property type="entry name" value="DNAPOLI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00474">
        <property type="entry name" value="35EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00475">
        <property type="entry name" value="53EXOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00279">
        <property type="entry name" value="HhH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00482">
        <property type="entry name" value="POLAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47807">
        <property type="entry name" value="SSF47807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56672">
        <property type="entry name" value="SSF56672"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="SSF88723"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00593">
        <property type="entry name" value="pola"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00447">
        <property type="entry name" value="DNA_POLYMERASE_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0227">DNA damage</keyword>
    <keyword evidence="11" id="KW-0234">DNA repair</keyword>
    <keyword evidence="11" id="KW-0235">DNA replication</keyword>
    <keyword evidence="9 11" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8 11" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5 11" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="53EXOc" evidence="13">
        <location>
            <begin position="1"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="3'-5' exonuclease" evidence="12">
        <location>
            <begin position="324"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="domain" description="POLAc" evidence="14">
        <location>
            <begin position="680"/>
            <end position="887"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00020311"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="SMART" id="SM00482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KPL79189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="932" mass="103022" checksum="A709525DB6AF3777" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GKM1</accession>
    <name>A0A0N8GKM1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_18740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70082">
        <property type="protein sequence ID" value="KPL70082"/>
        <property type="gene ID" value="ADN00_18740"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="124" mass="13942" checksum="3BFCBED04E7B3303" modified="2016-01-20" version="1">MASFSIEHLIIQLYKGVCGCVKKVKKLVGARGFDVTPRWGAAACKQKEPHNETLCIHWSGREDLMSPLDGERRPANKKSLTMRLFAFTGRGERIRTSGLLHPMPKGEKRDLKQPYTPKMGGYCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GKM3</accession>
    <name>A0A0N8GKM3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_18820</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064582.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18820"/>
    <dbReference type="EnsemblBacteria" id="KPL70098">
        <property type="protein sequence ID" value="KPL70098"/>
        <property type="gene ID" value="ADN00_18820"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="258" mass="28089" checksum="DD419C0DA14DDF36" modified="2016-01-20" version="1">MDLSIQEKQNSFALAPTERVITPGIWKMINEMAPVMYRSRLFGVTSPEAAAAIMLKGFEMGLSITASFELIQVVQGKPGLSPRGALAMLLNSPKIKKIEIKELTKNGQYIGHSCYMQRDNGFEYSVSFTIEDARNAGLIKPQSGWEHYPKNMCQWRAVGFTADVVAPDIVAGMTSIMKMPEEFGLALTEDGDIIDLKSMPTIEQSQTQSVQAEADIPSLDELVAQYGAEAVMVANEGAIPRTNEELVKAAAKLAGGVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GLY2</accession>
    <name>A0A0N8GLY2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_14345</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000034">
        <property type="protein sequence ID" value="KPL73770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14345"/>
    <dbReference type="EnsemblBacteria" id="KPL73770">
        <property type="protein sequence ID" value="KPL73770"/>
        <property type="gene ID" value="ADN00_14345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="ADH_N" evidence="4">
        <location>
            <begin position="24"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="ADH_zinc_N" evidence="3">
        <location>
            <begin position="173"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL73770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="358" mass="39576" checksum="0F7B03D52C262E00" modified="2016-01-20" version="1">MRAAVYYNNSDIRIEEMPIPEIGPDEVLVKTIASGICGGELMEWYHAPRAPKVMGHEPAGIIVDKGSQVKNFNVGDRVFVNHYVSCGTCRQCLRGRFTLCEHLKESKLFPGTTCEYFRVPSRQLNRDTLIIPDNVTFAEATVCEPWGCVLGGLKVTEILPGDTVLVIGAGFMGMGFLHMAPLFGAGKVISMDLSDWRLNKSLSMGATHTINPKTENPEEKLRDINGGYLADVVIVTVPTVQLYSQGHNLVERGGFLHLGAPTMPEPLWTINPQRQYFTEMKVSAKYSADHNDTSQIMKWLAAGRIDAKAAITHRCELDDTFSAFRMMLDAGESLKTVVYPHGIDQEIQPVSKKIGTDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMR2</accession>
    <name>A0A0N8GMR2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Putative gluconeogenesis factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_11645</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Required for morphogenesis under gluconeogenic growth conditions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the gluconeogenesis factor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063189.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11645"/>
    <dbReference type="EnsemblBacteria" id="KPL76010">
        <property type="protein sequence ID" value="KPL76010"/>
        <property type="gene ID" value="ADN00_11645"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3804"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043743">
        <property type="term" value="F:LPPG:FO 2-phospho-L-lactate transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10680">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00973">
        <property type="entry name" value="Gluconeogen_factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002882">
        <property type="entry name" value="CofD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038136">
        <property type="entry name" value="CofD-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010119">
        <property type="entry name" value="Gluconeogen_factor"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30135">
        <property type="entry name" value="PTHR30135"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01933">
        <property type="entry name" value="CofD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142338">
        <property type="entry name" value="SSF142338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01826">
        <property type="entry name" value="CofD_related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="32"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL76010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="449" mass="49489" checksum="8C150BC7E220272D" modified="2016-01-20" version="1">MKRNHNPWYQKLITLFRRDLRWLSPGLGVKRWIALILAGTTLIAIGFAFLLLDVYRTAPSSTWWLRVISLLSLRFLDRTLRAVIFGGFGVALVLIGNWGLNRALLKPFVKPGRQIYDMVSAYRRKERGPKVVVIGGGTGLSALLRGVKEYTTNITAIVTVADDGGSSGELRRTVGILPPGDIRNCLAALSNDEALLTQIFQYRFSTAAGLNGHTLGNLLITALTELTGSFEEAVAETGRVLAVQGRVLPATLHDVRLVADVQMPNGEGVVQQVRGESQIPKAAGKVLRVWLEPDSPQAFPPTLQALLSADLIVVGPGSLYTSIIPNLLVPDIAGALRASRALKFYVCNVATQPGETDGYQCGDHLITLEKHVGTRLFDLLISNNRFEGKLPENLDWVKTEAQLQHTYSVYSADLVDLENPWRHDSKKLAKTIMDLYYERTGPLLTREED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMR6</accession>
    <name>A0A0N8GMR6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Type II secretion system protein E</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_11850</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GSP E family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063227.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11850"/>
    <dbReference type="EnsemblBacteria" id="KPL76042">
        <property type="protein sequence ID" value="KPL76042"/>
        <property type="gene ID" value="ADN00_11850"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3846"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001482">
        <property type="entry name" value="T2SS/T4SS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00437">
        <property type="entry name" value="T2SSE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="T2SP_E" evidence="2">
        <location>
            <begin position="80"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006611"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL76042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="438" mass="48160" checksum="5AADE5460FD175D5" modified="2016-01-20" version="1">MERPDTSSLKSVDLSKLKSYLITTISRELEGKSVPAQQRREMVNSILQQAYQATKLQLPVGLRDQLFRDILDDIVGFGPLQPFLDDPEISEVMVNGPHQIYIERKGKLVRTQVMFEDDNAVLRVIDRIVSPLGRHIDRDNPTVDARLPDGSRVNAVIAPVAIDGPSITIRKFQKDKLTVDQLIAFGSLTPQMAEFIRACVVSRLNVIISGGTGSGKTTLLNVLSGFIPEEERIVTIEDAAELKLQQEHVVRLETKPADSSGHNEVPIRHLVRNALRMRPDRIVVGEVRGGEALDMLQAMNTGHDGSLTTLHANSPRDAISRLETMSLMSGMDLPLKVIRQQIASAVDLIVQQSRLRDGSRKVTAVTEVAGMEGDTVVMSDIFRFDQTGIGPDGAIIGELKPTGIRPMFIPRLEAAGFNLPATVFGANLGDMISSSRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GN71</accession>
    <name>A0A0N8GN71_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_09100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77282">
        <property type="protein sequence ID" value="KPL77282"/>
        <property type="gene ID" value="ADN00_09100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018309">
        <property type="entry name" value="Tscrpt_reg_PadR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005149">
        <property type="entry name" value="Tscrpt_reg_PadR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03551">
        <property type="entry name" value="PadR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10400">
        <property type="entry name" value="Vir_act_alpha_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PadR" evidence="1">
        <location>
            <begin position="2"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="Vir_act_alpha_C" evidence="2">
        <location>
            <begin position="78"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="166" mass="19971" checksum="2CA10334AF91ADF7" modified="2016-01-20" version="1">MSGYDLKQILDHSTAHFWHAHHSQIYTNLRQMEEEGLVTSQFIQEEGQPNRRIYHVTEMGKAALKGWLDRPMQEMSPIKEELLVRLFFSGQRESHQIIAELQHQRRLHLQRLKEYENITVRMGDEKKPIELERESRFWHATIQLGLRYEKAYLEWLDETIQMVESL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GN80</accession>
    <name>A0A0N8GN80_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NADP transhydrogenase subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_08870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08870"/>
    <dbReference type="EnsemblBacteria" id="KPL77354">
        <property type="protein sequence ID" value="KPL77354"/>
        <property type="gene ID" value="ADN00_08870"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003421">
        <property type="entry name" value="Opine_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02317">
        <property type="entry name" value="Octopine_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Octopine_DH" evidence="1">
        <location>
            <begin position="173"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="354" mass="38874" checksum="FDE40B8C15119AA5" modified="2016-01-20" version="1">MAAHLALMEFPTTLYNRTPDHIAAIKELGGIDLECCEGGPHGFGKLACVTSNIAEALENADMIMVVVPSSAHAEIAKNCAPYLKDGQIVLLHPGRTCGAIEFQKVLHDNHCTADVTVAEAETFIYASRSDGPAQARIFRIKEAVPLAALPATRTRSVLDMIHQAYSQYIDGVNVLQTGLNNMGAIFHPALTILNAGWIETTHGDFEFYIDGVSTSVARVLEALDRERVTVAASLGIRGRTAMEWLKLAYDTVGEDLHQAIHNQPGYYGIKAPTTLYHRYIFEDVPMSMVPIASLGEHFGVSVRAMDSIIRLACIIHKTDYWRRGRTLDKLGIGHLSDSELTYLVNEGTPHEMFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GND9</accession>
    <name>A0A0N8GND9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_08035</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062472.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77826">
        <property type="protein sequence ID" value="KPL77826"/>
        <property type="gene ID" value="ADN00_08035"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL77826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="229" mass="24892" checksum="C965012E88E0E106" modified="2016-01-20" version="1">MIRFRNMVLAVFFAACALPGMLLSSQIMPLLKPVPQAVHITPVPLNTTPESQPIIREDQKWVVVAVSEDGSSQPQLAAVWGVFISFGDRSNLTFKEIYNPHAADTYGLASQFNISQDGAVDPRFSSALKQMNVNWNGTILINESAATILRNWLERGLTNTEALSSTSLPQSICAFLTVPNVERPQTSLPWELLLSGGLKTDLPAAQFTGIGDQLLQASPAPFCEVISIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNQ9</accession>
    <name>A0A0N8GNQ9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aldolase_II domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_06025</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06025"/>
    <dbReference type="EnsemblBacteria" id="KPL78786">
        <property type="protein sequence ID" value="KPL78786"/>
        <property type="gene ID" value="ADN00_06025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.225.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001303">
        <property type="entry name" value="Aldolase_II/adducin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036409">
        <property type="entry name" value="Aldolase_II/adducin_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00596">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01007">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53639">
        <property type="entry name" value="SSF53639"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldolase_II" evidence="1">
        <location>
            <begin position="2"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="216" mass="24242" checksum="469A834EB5AD7F89" modified="2016-01-20" version="1">MYVTSQGGNLSYKLEENLLIITPTCVTKCDVTEKDLVFIDLEGHIVEGTRKPTGEVPMYINFYRDRPDIKSVIHCHPPYTNTFTILKGPNWLMRPIYPETVAEVGPVPLVPYGEPLTQKLADNFAPFVKKYNAFLMENHGLTILSSADIVRTLQLVDILEVSSISILQALAVGGLKELSREDVQNLENTMKTRNLPMIGMPGVNVSMVDLYFPQEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNV3</accession>
    <name>A0A0N8GNV3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">3-oxoadipate:succinyl-CoA transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_04590</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061779.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04590"/>
    <dbReference type="EnsemblBacteria" id="KPL79138">
        <property type="protein sequence ID" value="KPL79138"/>
        <property type="gene ID" value="ADN00_04590"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.279"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008410">
        <property type="term" value="F:CoA-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004165">
        <property type="entry name" value="CoA_trans_fam_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01144">
        <property type="entry name" value="CoA_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00882">
        <property type="entry name" value="CoA_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="251" mass="27084" checksum="0D375730A3081BF8" modified="2016-01-20" version="1">MDYTASELMIVNAARLLRDGDSVFVGVGIPNLACNLARRTHAPNLLMIYEAGVIGARPARLPLSIGDPTLVSGATQVCGMFDIFSLYLQRGNVDVGFLGGAQIDRFGNINATVIGDYQHPKVRLPGSGGSMEIAAWANRCYIMTPHQKRRFPAKVDFCTSAGFLGGRAQREAAGIRGGGPQAVVTDLCILEPDETGELVVAALHPGATLEQAQANTGWELRPAREVKFTPPPTQEELRILREELDPQGIYR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNY0</accession>
    <name>A0A0N8GNY0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_03250</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000014">
        <property type="protein sequence ID" value="KPL79354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061523.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000014.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03250"/>
    <dbReference type="EnsemblBacteria" id="KPL79354">
        <property type="protein sequence ID" value="KPL79354"/>
        <property type="gene ID" value="ADN00_03250"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003445">
        <property type="entry name" value="Cat_transpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02386">
        <property type="entry name" value="TrkH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="72"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="129"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="184"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="228"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="271"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="327"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="389"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="450"/>
            <end position="470"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL79354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="476" mass="52392" checksum="D6F7AA5D119C060C" modified="2016-01-20" version="1">MIRQLPAPHPILRLVADFLLIFGVLLLIPLGIALFTGEQQQALTFGVMAAVFLVSMFWLRQSLPSPVIKERHAAIALAAGWILYSLFSAVPFIVFGLQPVDAFFEAFSGWSDTGLTMIPDPGILPYSLGFFRVLTQWVSGLGIVMFMLFLRGDSARAARGLFEAEGRFEDFTFNLWHIGRTVTLIYLAYTLVGFLGLWATGVPAFHALTHAITSLSTGGFSSNSVGVGLYGAAPSLVAMTIMLVGGISFSSHQALMVGKWRKMWNNPEVRALLVIIPLFAGLLLLELHITGSNPGEQILNGFFYVVSAVTTCGAGTTLQLSHLPDRVIFTLIFLMMTGAAYGSTTGGIKLWRVLIIFKLIQREIRRPFYPPGTLLPIRMGNNIVSDQTAIQIMAFVLLYLGIGMVGALFFMLFGYRALDALFTVFSAQGNVGLNAMPNALYYGMHPILKIQLMLHMFIGRVEIFPLIYLLRSFRSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GP34</accession>
    <name>A0A0N8GP34_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Cold-shock protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_02135</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000009">
        <property type="protein sequence ID" value="KPL79786.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061315.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000009.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02135"/>
    <dbReference type="EnsemblBacteria" id="KPL79786">
        <property type="protein sequence ID" value="KPL79786"/>
        <property type="gene ID" value="ADN00_02135"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04458">
        <property type="entry name" value="CSP_CDS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012156">
        <property type="entry name" value="Cold_shock_CspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011129">
        <property type="entry name" value="CSD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019844">
        <property type="entry name" value="CSD_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002059">
        <property type="entry name" value="CSP_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00313">
        <property type="entry name" value="CSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002599">
        <property type="entry name" value="Cold_shock_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00050">
        <property type="entry name" value="COLDSHOCK"/>
    </dbReference>
    <dbReference type="SMART" id="SM00357">
        <property type="entry name" value="CSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00352">
        <property type="entry name" value="CSD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51857">
        <property type="entry name" value="CSD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CSD" evidence="3">
        <location>
            <begin position="4"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL79786.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="69" mass="7744" checksum="DF0A7DE3C6B6384E" modified="2016-01-20" version="1">MNERVTGTVKWFNTSKGYGFISRPEGPDVFVHYSAIEAEGFRNLEEGQTVEFNIEEGPKGLQASKVHLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GPC8</accession>
    <name>A0A0N8GPC8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_01445</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80538">
        <property type="protein sequence ID" value="KPL80538"/>
        <property type="gene ID" value="ADN00_01445"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL80538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="62" mass="7286" checksum="A81BB094B1CB9EAA" modified="2016-01-20" version="1">MTVWKGRWWLSGVQPTHRYFAAPQKPEKTFFWGEQPKGQPIFRPPGQPHPAIFLLKLHQTGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GPG4</accession>
    <name>A0A0N8GPG4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Molybdopterin molybdenumtransferase</fullName>
            <ecNumber evidence="7">2.10.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_01130</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenylyl-molybdopterin + H(+) + molybdate = AMP + H2O + Mo-molybdopterin</text>
            <dbReference type="Rhea" id="RHEA:35047"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:36264"/>
            <dbReference type="ChEBI" id="CHEBI:62727"/>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.10.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 7">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 7">Belongs to the MoeA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.10.1.1" evidence="7"/>
    <dbReference type="EMBL" id="LGCL01000003">
        <property type="protein sequence ID" value="KPL80826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061126.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01130"/>
    <dbReference type="EnsemblBacteria" id="KPL80826">
        <property type="protein sequence ID" value="KPL80826"/>
        <property type="gene ID" value="ADN00_01130"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1971"/>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061599">
        <property type="term" value="F:molybdopterin molybdotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032324">
        <property type="term" value="P:molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00887">
        <property type="entry name" value="MoeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036425">
        <property type="entry name" value="MoaB/Mog-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001453">
        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038987">
        <property type="entry name" value="MoeA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005111">
        <property type="entry name" value="MoeA_C_domain_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036688">
        <property type="entry name" value="MoeA_C_domain_IV_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005110">
        <property type="entry name" value="MoeA_linker/N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036135">
        <property type="entry name" value="MoeA_linker/N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024370">
        <property type="entry name" value="PBP_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10192">
        <property type="entry name" value="PTHR10192"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00994">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03454">
        <property type="entry name" value="MoeA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03453">
        <property type="entry name" value="MoeA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12727">
        <property type="entry name" value="PBP_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00852">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53218">
        <property type="entry name" value="SSF53218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63867">
        <property type="entry name" value="SSF63867"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63882">
        <property type="entry name" value="SSF63882"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="6 7" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MoCF_biosynth" evidence="8">
        <location>
            <begin position="189"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL80826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="656" mass="70832" checksum="D2541223FF7F1F68" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GPG7</accession>
    <name>A0A0N8GPG7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_01285</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000003">
        <property type="protein sequence ID" value="KPL80850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061153.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000003.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80850">
        <property type="protein sequence ID" value="KPL80850"/>
        <property type="gene ID" value="ADN00_01285"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL80850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="67" mass="7639" checksum="4AA9CC136D4401B5" modified="2016-01-20" version="1">MLNRLKILLEQPEYSALIHLAEQELRTPADQARLIIRLDLIQRGILSAADCPCTQPQENDVRHESSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GPK2</accession>
    <name>A0A0N8GPK2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Acetyl-CoA synthetase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_01000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061086.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01000"/>
    <dbReference type="EnsemblBacteria" id="KPL81130">
        <property type="protein sequence ID" value="KPL81130"/>
        <property type="gene ID" value="ADN00_01000"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3600"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043758">
        <property type="term" value="F:acetate-CoA ligase (ADP-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.261">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043938">
        <property type="entry name" value="Ligase_CoA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032875">
        <property type="entry name" value="Succ_CoA_lig_flav_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016102">
        <property type="entry name" value="Succinyl-CoA_synth-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13380">
        <property type="entry name" value="CoA_binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19045">
        <property type="entry name" value="Ligase_CoA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13607">
        <property type="entry name" value="Succ_CoA_lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00881">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52210">
        <property type="entry name" value="SSF52210"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="2">
        <location>
            <begin position="493"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL81130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="704" mass="75145" checksum="A3F9A149991780EA" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WK50</accession>
    <name>A0A0P6WK50_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Polysacc_synt_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_18525</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the polysaccharide synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064530.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18525"/>
    <dbReference type="EnsemblBacteria" id="KPL70052">
        <property type="protein sequence ID" value="KPL70052"/>
        <property type="gene ID" value="ADN00_18525"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3013"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05237">
        <property type="entry name" value="UDP_invert_4-6DH_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003869">
        <property type="entry name" value="Polysac_CapD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02719">
        <property type="entry name" value="Polysacc_synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="38"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="80"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="Polysacc_synt_2" evidence="3">
        <location>
            <begin position="293"/>
            <end position="575"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL70052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="630" mass="69550" checksum="F9ED1773D2C6C978" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WK89</accession>
    <name>A0A0P6WK89_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_18875</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064594.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70107">
        <property type="protein sequence ID" value="KPL70107"/>
        <property type="gene ID" value="ADN00_18875"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="80" mass="9409" checksum="3EF57512F20DCE30" modified="2016-01-20" version="1">MAAKSDFEIICDQIDELAEAEEDLASNPDQLSMFMSDWNNIIFWFQDIRERFSQTEEATILQKFAAVKPIAEKLKLTWYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WK91</accession>
    <name>A0A0P6WK91_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_18925</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064604.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70116">
        <property type="protein sequence ID" value="KPL70116"/>
        <property type="gene ID" value="ADN00_18925"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="67" mass="7520" checksum="B47744C3D12B1906" modified="2016-01-20" version="1">MSTFLNREQAQKQNEHILEEQISALSAENAVLHEMLGNYAAKVAKLEFEILLLHSREEGIDGGNQPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WN72</accession>
    <name>A0A0P6WN72_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PHB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_17520</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064343.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL71478">
        <property type="protein sequence ID" value="KPL71478"/>
        <property type="gene ID" value="ADN00_17520"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="49"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="PHB" evidence="3">
        <location>
            <begin position="192"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL71478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="456" mass="52014" checksum="8F5571BF89BAEED8" modified="2016-01-20" version="1">MSDMINPEDLEEPEESESPLQRLERAAEEIESRLPFPPSESDLQELGGLIRLFIIIPAILAAFAFLGDILFEHVDAVALAQHIREINPFARPLPDWMLTVMAFLFNGQNFRYMIAPTTAIILVIFGAANYVRNVYHLPDFKMGLRYVIASIFALRYPRLEIDNGLKKIKDGEVNLLDRIGGPGYALVQPGNAVMFRTLREPSRMRGSGAHFLLPFETIGQIASLDEQHGRLDELQVTTRDGFRVMLREVQFRFRIDAQNWQRTLETPYPYSEESFYNMAYNLSVRDDGPRPWKATVRQMVVGAIMDYINSHDIDFLTAPREKERDPRRELKNELFAQAVSQRMRRAGASLLWIDVGFFDVVEPDVDQKRIDLWKADWVGNAKVSLAYGEAKRMAYLELGRAEAQAELIMSITHALENVDFARGNPQNLRSILLSRTAQILEAISSENKDLPQGPKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WQF0</accession>
    <name>A0A0P6WQF0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GAF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_15835</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064003.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15835"/>
    <dbReference type="EnsemblBacteria" id="KPL72283">
        <property type="protein sequence ID" value="KPL72283"/>
        <property type="gene ID" value="ADN00_15835"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="134"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="179"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="GAF" evidence="3">
        <location>
            <begin position="258"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="208"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL72283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="583" mass="64406" checksum="392427D47C44F117" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WT05</accession>
    <name>A0A0P6WT05_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltransf_25 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_15380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063920.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15380"/>
    <dbReference type="EnsemblBacteria" id="KPL72206">
        <property type="protein sequence ID" value="KPL72206"/>
        <property type="gene ID" value="ADN00_15380"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransf_25" evidence="1">
        <location>
            <begin position="43"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="266" mass="30172" checksum="7E3493DE932D4FCD" modified="2016-01-20" version="1">MKIEYQETTNDLMTRIDIHNRFGGRNIDEWMLQILPLQKGMKILDVGCGAGKQCFGYHNHLQGECDITGGDVNEELLTKARTENAKIGNPVKFMSLNFNERFPFEDNSFDLLSCCFAIYYAEDIPFTIREMHRVLKPGGTLFSSGPMPDNKKTFYDIIREATGKPIPPMPGSSRYSTEIYGAVKDTFSSSRVEIFENPLTFTNAQPFIDYTRASLSEDRKLWGSLFQGADDFEKVMEKITEVANRWVERDGKIVMTKVVGGILGTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WT21</accession>
    <name>A0A0P6WT21_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_15550</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063947.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72233">
        <property type="protein sequence ID" value="KPL72233"/>
        <property type="gene ID" value="ADN00_15550"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="321" mass="35722" checksum="0C75CE270EAD0D0B" modified="2016-01-20" version="1">MDEEILNNIMEVNHHKYYFEIPNMVDDLELSPYAFRLYAHLKRVAGENGASWQSNSTLAKVCKMSAGSVVNAKRELQDAGLIVVTLETTKDNNRYHNITIVDIWANNFKKFTQNGVGRSSGEHPSSPGEHPPSPGELKNNPIKNNPVKNNPNTCAVPRRERVTAAKKQGDLLDGILSFAEKSEDPLANFPEAVKPTLKAFLDLWKIDPPRPPQRGRGGTFAQWIKEAQDLQSACRDYPLNKVLQAVYSDWLKSTYCVDHPGAILRSVRGKVIEFRAKGVQAETPKVGLENYDPAEVAEFQAKLNQARQNSSSGLSPFPGVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WY96</accession>
    <name>A0A0P6WY96_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">Flagellar hook protein FlgE</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_17100</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the flagella basal body rod proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064265.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17100"/>
    <dbReference type="EnsemblBacteria" id="KPL71409">
        <property type="protein sequence ID" value="KPL71409"/>
        <property type="gene ID" value="ADN00_17100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.482"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.98.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011491">
        <property type="entry name" value="Falgellar_hook_FlgE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037058">
        <property type="entry name" value="Falgellar_hook_FlgE_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001444">
        <property type="entry name" value="Flag_bb_rod_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019776">
        <property type="entry name" value="Flagellar_basal_body_rod_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020013">
        <property type="entry name" value="Flagellar_FlgE/F/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010930">
        <property type="entry name" value="Flg_bb/hook_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037925">
        <property type="entry name" value="FlgE/F/G-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07559">
        <property type="entry name" value="FlaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00460">
        <property type="entry name" value="Flg_bb_rod"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06429">
        <property type="entry name" value="Flg_bbr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117143">
        <property type="entry name" value="SSF117143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03506">
        <property type="entry name" value="FlgEFG_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00588">
        <property type="entry name" value="FLAGELLA_BB_ROD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flg_bb_rod" evidence="4">
        <location>
            <begin position="7"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="FlaE" evidence="6">
        <location>
            <begin position="189"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="Flg_bbr_C" evidence="5">
        <location>
            <begin position="329"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF06429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF07559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL71409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="408" mass="42609" checksum="CA4D1C812EE68C5E" modified="2016-01-20" version="1">MLRSMFTAISALNLHQDYLDVISDNLANANTTGFKSSRVVFQDLLSEVISPGAAPAGSKGGVNPTQIGLGAQLGYIAPVFTQGMTQSTGRNLDCAIQGEGFFIFDQGLDRRYSRDGSFTVDASGYLVSSSSGLRVQGWQNPNPGATTLDTNAGIGEIIIPLDNTIARETATVRLGGNLDSETAIDGIVNTSFTVFDSMGVTHNPAVRFTRTGANTWSWTATSPAGVTGSGTVTFDSSGHVSATNPATSTITFPGSTGAEQVDFTVDMTDITMLANSNSVASTFQDGLAAGSVSDIYIAQNTGQVYAVYSNGLKELVGQVALASFTNPSGLIRDGGNYFMIGLNSGEPAISAADSAGKGKIMTSSLEASNVDMAQEFTNMILAQRGFQASSRVISTSDEILQELVNLKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-08-12" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X2Q2</accession>
    <name>A0A0P6X2Q2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062926.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76973">
        <property type="protein sequence ID" value="KPL76973"/>
        <property type="gene ID" value="ADN00_10350"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="22"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="280" mass="31018" checksum="C29A7AABB607EF7F" modified="2016-01-20" version="1">MNQFKFKTMAVHESGLPEKPLVIFLHGGGAAGWMWQPVADLLGDSYRCWMPDLPGHGQSREAGRFRIRGAAQMVIDLVRAQAPDGRAHLVGLSEGAQVLVEMLSLDPGCIRSALVSSALLRPLPGMGWLASEGLLKATYVSSVAPFKNWDAYIRLNMKSAAGIPDQWFEPFKAEFQSLTAQSFADVMLENQRYRLPADLDKAHLPVLVLAGSREYAAMRQSARELAAALPNAKAYQFHLRRPASLAEQHNWPLNDPELFATVLRAWLDEEPLPEQFSALD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X326</accession>
    <name>A0A0P6X326_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Peptidase S41</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_14185</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063683.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000033.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14185"/>
    <dbReference type="EnsemblBacteria" id="KPL74143">
        <property type="protein sequence ID" value="KPL74143"/>
        <property type="gene ID" value="ADN00_14185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008236">
        <property type="term" value="F:serine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041489">
        <property type="entry name" value="PDZ_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005151">
        <property type="entry name" value="Tail-specific_protease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17820">
        <property type="entry name" value="PDZ_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03572">
        <property type="entry name" value="Peptidase_S41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00245">
        <property type="entry name" value="TSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="SSF50156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="PDZ" evidence="3">
        <location>
            <begin position="328"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="28"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="28"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL74143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="680" mass="73711" checksum="40A558BAAED82836" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X3W0</accession>
    <name>A0A0P6X3W0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Stage 0 sporulation protein J</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_11820</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ParB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063221.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11820"/>
    <dbReference type="EnsemblBacteria" id="KPL76037">
        <property type="protein sequence ID" value="KPL76037"/>
        <property type="gene ID" value="ADN00_11820"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3840"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041468">
        <property type="entry name" value="HTH_ParB/Spo0J"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004437">
        <property type="entry name" value="ParB/RepB/Spo0J"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003115">
        <property type="entry name" value="ParB/Sulfiredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036086">
        <property type="entry name" value="ParB/Sulfiredoxin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17762">
        <property type="entry name" value="HTH_ParB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02195">
        <property type="entry name" value="ParBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00470">
        <property type="entry name" value="ParB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110849">
        <property type="entry name" value="SSF110849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00180">
        <property type="entry name" value="parB_part"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ParB" evidence="4">
        <location>
            <begin position="29"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL76037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="285" mass="31069" checksum="1B833E7C34E32BF9" modified="2016-01-20" version="1">MARKGGLGKGLDALIPSQPVEGQTPTQGMAVSIAKIVPNPRQPRQVLREEDLQDLAASIKEHGIIQPLIVSYDAAADTYILIAGERRLKAAAMAGLTAVPVVIRQVNDQQQLELALIENIQRADLSPLETAEAYQHLHNDFGLSHEEIAVRVGKSRVAVTNTLRLLKLPESILKALTLGEISEGHARALLALTSSQAQVAALQTILNQKLTVRQTEELVQKLSGEKPAALPRKPIAPEIKALEEKLRDQLGTRVTMRHGKKGGTLTLHYYSTEELDTLLSILLKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X4H1</accession>
    <name>A0A0P6X4H1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methylmalonyl-CoA carboxyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_10950</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063052.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10950"/>
    <dbReference type="EnsemblBacteria" id="KPL76485">
        <property type="protein sequence ID" value="KPL76485"/>
        <property type="gene ID" value="ADN00_10950"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.883"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009317">
        <property type="term" value="C:acetyl-CoA carboxylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034733">
        <property type="entry name" value="AcCoA_carboxyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000438">
        <property type="entry name" value="Acetyl_CoA_COase_Trfase_b_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011763">
        <property type="entry name" value="COA_CT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011762">
        <property type="entry name" value="COA_CT_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01039">
        <property type="entry name" value="Carboxyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01070">
        <property type="entry name" value="ACCCTRFRASEB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50989">
        <property type="entry name" value="COA_CT_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50980">
        <property type="entry name" value="COA_CT_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CoA carboxyltransferase N-terminal" evidence="1">
        <location>
            <begin position="4"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="CoA carboxyltransferase C-terminal" evidence="2">
        <location>
            <begin position="268"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL76485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="518" mass="55930" checksum="A3D8781AAAB23395" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5J6</accession>
    <name>A0A0P6X5J6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_13005</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000028">
        <property type="protein sequence ID" value="KPL75304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063454.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000028.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13005"/>
    <dbReference type="EnsemblBacteria" id="KPL75304">
        <property type="protein sequence ID" value="KPL75304"/>
        <property type="gene ID" value="ADN00_13005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005537">
        <property type="entry name" value="RAMP_III_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03787">
        <property type="entry name" value="RAMPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="417"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="425"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL75304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="440" mass="50439" checksum="B96C162745845E94" modified="2016-01-20" version="1">MTYILPYNFVRLQPIPAGDRKKPTSHGNPDPDQELHSGRLTCRIICISPIFILPTNHTRSVSLGWDDNGNLGSHNIYEQFFCLKNDFPVIPASSIKGSIRLVAEALCNGCMSTFAESYESSRDHTHRYHLTSNSIYSCSEPFNLCPTCRIFGMATESQQNNQTKSNEKLFYRGKLEFSHARLAAIKVDYFEDPIMLPVMGNPRADVAVKVYGDNIGNARGRKFYYHRHDLQIIPSPNGYDTLKRWEQTKQPRNIRGFRWNMRPTIRPLHAGSIFEFDVEYQSLEKEELDLLITALELFPNLIDDQGKSIVPDSTMKFNEDYFVGEGVYHKFGYGKPAGLGSAACYITHWRVLHLQNRYQASPAVDGGWVEVQNLRQAVEDHKNKFKNVHGSQTYFKDLMAILRYPHGITKMQHIEQGDPAEQHLPPVPGKEKEWLKEQEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5U6</accession>
    <name>A0A0P6X5U6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF3828 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_09145</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062690.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77289">
        <property type="protein sequence ID" value="KPL77289"/>
        <property type="gene ID" value="ADN00_09145"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024289">
        <property type="entry name" value="DUF3828"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12883">
        <property type="entry name" value="DUF3828"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132854" description="DUF3828 domain-containing protein" evidence="1">
        <location>
            <begin position="22"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3828" evidence="2">
        <location>
            <begin position="69"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="463" mass="51681" checksum="764F13E0570868B0" modified="2016-01-20" version="1">MKKSKLLALFLFMAVVLQSCAPVQTQNLDIPDENPLAETPPLATLPPAIAETPSSQITPTLARVENGPLAVAESFYDWYFAQPSGEVLTDRSYASSPYLSEIWKSDLGYLLDSFENQAGYDPFTCAQNRLPSLSFDPVFISAGDAYIVGNVISNGAVQHYFVVQLGQGEGEWKIDAVHCPFDPQTTVMAFYTWYLGTIYQGTDAQSSAIEPRNPIAEGLLEGFYLASPALIDGIETELREMRETGGAYDPILNAQAIPLAFWVEPGQEGSDIQVRLTYGPQSSRYSVVHLVPSERLYWLVDKIEQVEVPVFDPQANLEVGTEDWQEYRDEAYGFSMRIPSHWTTEAADLSAMPADNAVKKGVFFLADWADPDLPVLWLNVLEGTEEQVSQYYPVESHQVIDLGGNAVWVDRDQCETRFVFQHPRQANVWLVIGDTCSSMPGRERYAEELEQIMAPLLRTVTFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5W0</accession>
    <name>A0A0P6X5W0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_12940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063438.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000027.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL75542">
        <property type="protein sequence ID" value="KPL75542"/>
        <property type="gene ID" value="ADN00_12940"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000424">
        <property type="entry name" value="Primosome_PriB/ssb"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50935">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL75542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="143" mass="16410" checksum="5A8E36CC0A744B0F" modified="2016-01-20" version="1">MINDVVLEGIVVREPWKFMEDLFFRMAVFRDTDLPAKPLDADRDAADYINIRICGGASGLITMRRGMRLRIHGFFQSRDYKENLAEIVEKAQKRSGVEISVDVKDMKPEQVAIERNSVEVVARRLIVLDKNAERKEKPESVST</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X741</accession>
    <name>A0A0P6X741_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_12370</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the glycosyltransferase 87 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063324.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76127">
        <property type="protein sequence ID" value="KPL76127"/>
        <property type="gene ID" value="ADN00_12370"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018584">
        <property type="entry name" value="GT87"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09594">
        <property type="entry name" value="GT87"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="102"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="135"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="182"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="210"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="267"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="295"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="317"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="344"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="367"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL76127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="406" mass="45280" checksum="82C6B9835DF13165" modified="2016-01-20" version="1">MSSSQKYLTFFVGLLLLTAILAVAIHTLTAGNTIGADFMVFYLAGRSSFIEGNGPYTAENNLLSQLAINERPADPSEDQLTFSYPPYVLLAIFPLVYLPFTWAQAVWMALLLVLQILLPLFLFPRAPRWAVATSFLLYPITLGFILGNFAAPIGVFLLAVYAVLFNQEQSPSHIADALAGMGLAWCTAKPQFSWLIILFLLLAALKQRRWWLLGAFSCAMVTFLAASFLILPSWPVDWVSQVLYYAQTNRTLLHLTLLLQLVLPGPLSTALTPVLVGLALIGAGFVLYRWWQGKTSALAALSWVALITYLVHPRGVAYEQITFLIPFLLWVFTPAAPRLTLTRGMSWILAIAASWLGFYGARFASGYYALPEWILAFYVLWMILYLTHWQKAERPLPSQTTTAPLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X767</accession>
    <name>A0A0P6X767_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L7/L12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rplL</name>
        <name evidence="7" type="ORF">ADN00_17700</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Forms part of the ribosomal stalk which helps the ribosome interact with GTP-bound translation factors. Is thus essential for accurate translation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer. Part of the ribosomal stalk of the 50S ribosomal subunit. Forms a multimeric L10(L12)X complex, where L10 forms an elongated spine to which 2 to 4 L12 dimers bind in a sequential fashion. Binds GTP-bound translation factors.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000043">
        <property type="protein sequence ID" value="KPL70881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064381.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000043.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17700"/>
    <dbReference type="EnsemblBacteria" id="KPL70881">
        <property type="protein sequence ID" value="KPL70881"/>
        <property type="gene ID" value="ADN00_17700"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2131"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00387">
        <property type="entry name" value="Ribosomal_L7_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00368">
        <property type="entry name" value="Ribosomal_L7_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000206">
        <property type="entry name" value="Ribosomal_L7/12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014719">
        <property type="entry name" value="Ribosomal_L7/12_C/ClpS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013823">
        <property type="entry name" value="Ribosomal_L7/L12_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008932">
        <property type="entry name" value="Ribosomal_L7/L12_oligo"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036235">
        <property type="entry name" value="Ribosomal_L7/L12_oligo_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45987">
        <property type="entry name" value="PTHR45987"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00542">
        <property type="entry name" value="Ribosomal_L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16320">
        <property type="entry name" value="Ribosomal_L12_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48300">
        <property type="entry name" value="SSF48300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54736">
        <property type="entry name" value="SSF54736"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00855">
        <property type="entry name" value="L12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_L12_N" evidence="6">
        <location>
            <begin position="5"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L12" evidence="5">
        <location>
            <begin position="59"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007197"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL70881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="125" mass="12804" checksum="C5671271D63F989E" modified="2016-01-20" version="1">MADLDKIIEQLSALTVLEAAELVKALEEKWGVSAAAPVAVAAAAPVAAAAEPEEEKTEFDVVLKDAGPKKIEVIKVIRQLTSLGLVEAKQMAETAGSKVLTAVSKEAAADAKAKLEAAGGVIELA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7B0</accession>
    <name>A0A0P6X7B0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aspartate-semialdehyde dehydrogenase</fullName>
            <ecNumber evidence="3">1.2.1.11</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_08005</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.11" evidence="3"/>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062466.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08005"/>
    <dbReference type="EnsemblBacteria" id="KPL77820">
        <property type="protein sequence ID" value="KPL77820"/>
        <property type="gene ID" value="ADN00_08005"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.601"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004073">
        <property type="term" value="F:aspartate-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005676">
        <property type="entry name" value="Asp_semi-ald_DH_pep-lack"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000534">
        <property type="entry name" value="Semialdehyde_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012280">
        <property type="entry name" value="Semialdhyde_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01118">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02774">
        <property type="entry name" value="Semialdhyde_dhC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00859">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00978">
        <property type="entry name" value="asd_EA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Semialdhyde_dh" evidence="2">
        <location>
            <begin position="6"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="280"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="351" mass="38244" checksum="F185B1A0B58309BF" modified="2016-01-20" version="1">MASKIPVVVLAATGSVGQRFVQLLDQHPWFEVVALTASERSEGKTYQEACNWLLSTPMPDWARSMPVLPTHPTGIQAKIAFSALPASSAKDIEPEFARAGMAVCSNAAAYRREPDVPILLPEINAEHIHLIPAQRKNRGWDGFITTNPNCSSTGMTIALRPILDQFGVKRVFVTTLQAISGAGYPGVASMDILDNVVPYIGGEEEKIEWEPRKMLGKVQGDQIALADFRVSAQVNRVPVVDGHLVCLSMELEKKTSPDEVIQALRAYQLPELCQGLPSAPQPPIVVMDEPNRPQPRLDRMRGDGMTTTVGRVRVDPLLDIKMVVLSHNTIRGAAGGSLMNAELLVKTGFVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7C3</accession>
    <name>A0A0P6X7C3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Leucine--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Leucyl-tRNA synthetase</fullName>
            <shortName evidence="8">LeuRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">leuS</name>
        <name evidence="14" type="ORF">ADN00_18475</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu)</text>
            <dbReference type="Rhea" id="RHEA:11688"/>
            <dbReference type="Rhea" id="RHEA-COMP:9613"/>
            <dbReference type="Rhea" id="RHEA-COMP:9622"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57427"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78494"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8 9">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.4" evidence="8"/>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064523.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18475"/>
    <dbReference type="EnsemblBacteria" id="KPL70044">
        <property type="protein sequence ID" value="KPL70044"/>
        <property type="gene ID" value="ADN00_18475"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3003"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004823">
        <property type="term" value="F:leucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006429">
        <property type="term" value="P:leucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00049_B">
        <property type="entry name" value="Leu_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002302">
        <property type="entry name" value="Leu-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025709">
        <property type="entry name" value="Leu_tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015413">
        <property type="entry name" value="Methionyl/Leucyl_tRNA_Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43740">
        <property type="entry name" value="PTHR43740"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13603">
        <property type="entry name" value="tRNA-synt_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09334">
        <property type="entry name" value="tRNA-synt_1g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00985">
        <property type="entry name" value="TRNASYNTHLEU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="SSF50677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00396">
        <property type="entry name" value="leuS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1g" evidence="12">
        <location>
            <begin position="43"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-synt_1_2" evidence="13">
        <location>
            <begin position="226"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-synt_1" evidence="10">
        <location>
            <begin position="424"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_1" evidence="11">
        <location>
            <begin position="660"/>
            <end position="776"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="8">
        <location>
            <begin position="46"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="8">
        <location>
            <begin position="586"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="589"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF09334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF13603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KPL70044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="818" mass="94190" checksum="DAC9BB44DF6CC650" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7Z8</accession>
    <name>A0A0P6X7Z8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_04600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061781.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79140">
        <property type="protein sequence ID" value="KPL79140"/>
        <property type="gene ID" value="ADN00_04600"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="88" mass="9913" checksum="395AD635D11BD317" modified="2016-01-20" version="1">MNFFNRFGSFLLILGGMGILLFLFSDIAQARNYAYLLAGVALIAVGALFKSAGPKPTPEPSSRFSMIRRIRQQQLERSKSRMQKKKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X890</accession>
    <name>A0A0P6X890_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_11100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063081.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11100"/>
    <dbReference type="EnsemblBacteria" id="KPL76511">
        <property type="protein sequence ID" value="KPL76511"/>
        <property type="gene ID" value="ADN00_11100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.916"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002825">
        <property type="entry name" value="Pept_S49_ser-pept_pro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01972">
        <property type="entry name" value="SDH_sah"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="284" mass="31465" checksum="BDD21D90024ECE8A" modified="2016-01-20" version="1">MELLNLLWIFLAISSVIPVIRQKMLEASRVRMLRALEEKRGSRVITLIHRQESMSFLGFPMARYIDIEDSEQVLRAIKLTDPNLPIDVLLHTPGGLVLAAEQIARALARHPARVAVFVPHYAMSGGTMIALAADEIIMDENAVLGPTDPQIGNYPAASILRAVEQKSCDKVDDQTLILADIAGKAVNQVKETIRNLACVQYSAEKAEELAEKFASGCWTHDYPISVEEAKELGLKVSTDVPPEVYQIMNLYPQSRVRRPSVDYIPVPYSTPPAIPGGAERRARE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X8E9</accession>
    <name>A0A0P6X8E9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Putative agmatine deiminase</fullName>
            <ecNumber evidence="2">3.5.3.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Agmatine iminohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">aguA</name>
        <name evidence="3" type="ORF">ADN00_11465</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>agmatine + H2O = N-carbamoylputrescine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:18037"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:58145"/>
            <dbReference type="ChEBI" id="CHEBI:58318"/>
            <dbReference type="EC" id="3.5.3.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the agmatine deiminase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.3.12" evidence="2"/>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063151.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11465"/>
    <dbReference type="EnsemblBacteria" id="KPL76566">
        <property type="protein sequence ID" value="KPL76566"/>
        <property type="gene ID" value="ADN00_11465"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.994"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047632">
        <property type="term" value="F:agmatine deiminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004668">
        <property type="term" value="F:protein-arginine deiminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009446">
        <property type="term" value="P:putrescine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01841">
        <property type="entry name" value="Agmatine_deimin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017754">
        <property type="entry name" value="Agmatine_deiminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007466">
        <property type="entry name" value="Peptidyl-Arg-deiminase_porph"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31377">
        <property type="entry name" value="PTHR31377"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04371">
        <property type="entry name" value="PAD_porph"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03380">
        <property type="entry name" value="agmatine_aguA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Amidino-cysteine intermediate" evidence="2">
        <location>
            <position position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL76566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="365" mass="40437" checksum="31CC6BB9721786DE" modified="2016-01-20" version="1">MSKCIESTPRQDGFRMPGEFEPHAGCWMLWPERPDNWRNGAKPAQRAFAAVASAIAQFEPVTVGVSAGQFLNARHLLPASVRVVELSANDSWMRDCGPTFVVNGQGIVRGVDWDFNAWGGLEGGLYFPWDLDDLVPQKVCDIERLDRYKAAGFVLEGGSIHVDGEGTLLTTEECLLNTNRNPQLTREEIEENLREYLNIEKIIWLSRGVYNDETNGHVDNIACFIRPGVVALTWTDDQNDPQYEISADAYQRLSNAVDAQGRKLEVHKIHQPNPILITEEESLGVDTVDGTLPRNAGDRLAGSYINFYIANGGIVMPVFDDPHDQLAMDALGKLFPGRKVVGVNAREILLGGGNIHCITQQQPRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X8H9</accession>
    <name>A0A0P6X8H9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_16865</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL71485">
        <property type="protein sequence ID" value="KPL71485"/>
        <property type="gene ID" value="ADN00_16865"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="2">
        <location>
            <begin position="8"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="3">
        <location>
            <begin position="97"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL71485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="157" mass="17761" checksum="ADEEB1718ED3848E" modified="2016-01-20" version="1">MFCAQWERVYRLALHLTGCPDDAEDLSLETFCRLWSQPPEKIDNPVGWLLRVAANLGYNALRSARRRNQYEQQAGIQYWENTQSENPDQAAIAAANRLRVRQALAKLPAQQARLLALRYSGASYQEIAHALNLSPASVGKLLNRAEKQFCQVYGQGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X921</accession>
    <name>A0A0P6X921_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_12020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063259.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12020"/>
    <dbReference type="EnsemblBacteria" id="KPL76067">
        <property type="protein sequence ID" value="KPL76067"/>
        <property type="gene ID" value="ADN00_12020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="203"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="234"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="304"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="337"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="377"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="404"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="584" mass="65832" checksum="E7F031F3338E64A5" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9E6</accession>
    <name>A0A0P6X9E6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Hydrogenase maturation factor HypA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">hypA</name>
        <name evidence="5" type="ORF">ADN00_09700</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the HypA/HybF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062803.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09700"/>
    <dbReference type="EnsemblBacteria" id="KPL76868">
        <property type="protein sequence ID" value="KPL76868"/>
        <property type="gene ID" value="ADN00_09700"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2397"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051604">
        <property type="term" value="P:protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00213">
        <property type="entry name" value="HypA_HybF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000688">
        <property type="entry name" value="HypA/HybF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34535">
        <property type="entry name" value="PTHR34535"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01155">
        <property type="entry name" value="HypA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004761">
        <property type="entry name" value="Hydrgn_mat_HypA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 4" id="KW-0533">Nickel</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="4">
        <location>
            <position position="2"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL76868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="113" mass="12195" checksum="C87A6B98D35C1740" modified="2016-01-20" version="1">MHELGIMFNVVRSVESFAQKNGVKTIATLVLQIGELSPVVPQYIEACYPAAVDGTLLQDTELKIEILPGNALCQGCGKVFNLLASGKQCPHCGGQSWEVLSGREFMIKEIVAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9P8</accession>
    <name>A0A0P6X9P8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">D-ribose transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_06055</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78789.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062071.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78789">
        <property type="protein sequence ID" value="KPL78789"/>
        <property type="gene ID" value="ADN00_06055"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1690"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="6"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="254"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL78789.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="500" mass="55501" checksum="48AD8350F27CC965" modified="2016-01-20" version="1">MTDCLLEMRNISKEFSGVWVLQDVNLSLNKGEVHVLLGENGAGKSTLIKILSGAYTKTSGEILINGEKVDIKNPSDAFGYKIGVIYQEFNLNPFMSIYENLFLGKEYTNALGVIDKNRCIKEAKRALERVGLDVSPRTLVKDLSVAQMQLVEIAKAIMSQVQILVFDEPTATLTEREIEKLFQIICELRTNGVGIIYISHRMKELKQIGDRCTVLRDGNYIATVKLSEVEDCDLVRMMVGRTVEFEKRTESFIDKNEDVLSVEDLSCRNLIEGISFTLKKGEILGVAGLVGSGRTEMAKCIIGEYKPTRGTITIKGKQVKIKEPCDAISHGIVYLSEDRKNEGLIVKHDVKTNATLAGLDKLIKGGLINTEKEEDCANDLVKQFNIKTNGIKMLIKHLSGGNQQKVVIAKWVNSGADIYIFDEPTRGIDVGARQEIYSIMEDLARAGASIIMISSDLVEIIKMSDRVIVMHQGKVGGILENDVNLCQETILNYAIGRQCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9T1</accession>
    <name>A0A0P6X9T1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Lipoyl-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_10960</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063054.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10960"/>
    <dbReference type="EnsemblBacteria" id="KPL76487">
        <property type="protein sequence ID" value="KPL76487"/>
        <property type="gene ID" value="ADN00_10960"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001882">
        <property type="entry name" value="Biotin_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00188">
        <property type="entry name" value="BIOTIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0092">Biotin</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="2">
        <location>
            <begin position="63"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL76487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="143" mass="15529" checksum="440D3B63A494893B" modified="2016-01-20" version="1">MKMRVKIDEQFFDVEIENLEERPIRATVEGQTFEIWPEEEQETCEPAYTPPVPQLVVGSPASPVSAAIPTASSNSVKAPIPGVILAVHVKVGESVRAGQELCTLEAMKMKNAIRASRDGVIAAIHVQPGQTVQHGHALMDFSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XA30</accession>
    <name>A0A0P6XA30_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_11390</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063138.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11390"/>
    <dbReference type="EnsemblBacteria" id="KPL76588">
        <property type="protein sequence ID" value="KPL76588"/>
        <property type="gene ID" value="ADN00_11390"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.978"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL76588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="284" mass="31608" checksum="9123A5DE3B00A1DA" modified="2016-01-20" version="1">MIRVENLSYSYASTNHPALEGLSFTVKEGEIFGFLGPSGAGKSTTQKVLIGLLRDYQGSTQVMGRELSAWGADYYEQIGVSFEFPNHFLKLTAVENLTYFSRLYQTVRYTPRELLALVGLEPDGELLVSQYSKGMKNRLSVARALLHNPRILFLDEPTSGLDPLNARGIKDLILAQKSQGKTIFLTTHDMTIADELCDRVALIVDGRIRMVGAPRDLKLQHGRASVRVGYVNGGGQAQREFELAGLAENEDFLKLLRSENVQTLHSQEASLEDVFIEVTGRRLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XA73</accession>
    <name>A0A0P6XA73_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Response regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_16425</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064126.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72061">
        <property type="protein sequence ID" value="KPL72061"/>
        <property type="gene ID" value="ADN00_16425"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="3"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL72061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="142" mass="15726" checksum="FB20CD2E56B8C59E" modified="2016-01-20" version="1">MLRVMIAHQENSIRLALRMYLQAYPCVSVVCEVSRAGELLRDASLCQPELILMSWDLPDFEKFSVTGHWHKTSGSPSLNQVKGVIISALHKLPSEPTIIVTGNLQEDLFPVLYAGADDYLYQGEMPAKLAALMDAIQPPDVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XA98</accession>
    <name>A0A0P6XA98_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_03710</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061618.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79008">
        <property type="protein sequence ID" value="KPL79008"/>
        <property type="gene ID" value="ADN00_03710"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="659" mass="74494" checksum="F173A3C290C3FE10" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XB59</accession>
    <name>A0A0P6XB59_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_02565</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000012">
        <property type="protein sequence ID" value="KPL79420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061395.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000012.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02565"/>
    <dbReference type="EnsemblBacteria" id="KPL79420">
        <property type="protein sequence ID" value="KPL79420"/>
        <property type="gene ID" value="ADN00_02565"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004107">
        <property type="entry name" value="Integrase_SAM-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13495">
        <property type="entry name" value="Phage_int_SAM_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="5">
        <location>
            <begin position="15"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="4">
        <location>
            <begin position="128"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL79420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="337" mass="38233" checksum="1C32EFD9D15F2BC1" modified="2016-01-20" version="1">MNRSSPGTSKSKVSLSLAKAIDGFLKFKTAEGLSQRTITSYEFTLGHWLKYIGDREVSEIQSSDLTGYMAWLRTEYKPRRWNGSSEPLSAKSIRNVWVTFRSFFGWLQVEFKFPNPAKEITAPKFQKHPVETFTKEDVEKILKACVYSRESQTEERKKFVMRRPTANRDQAIVLMLLDTGLRATELCSLIINDVDLKTGKVTIRHGVAGGAKGGKGRTVYLGKVARKTVWRYLASREDGDDPDAPLFISHADRAFNKDSLRVLINRLGDRAEIKKAYPHKFRHTFAITYLRSGGDVFTLQSLLGHGSLDMVRHYAQIAEVDVEQAHRKASPADNMRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBW7</accession>
    <name>A0A0P6XBW7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ABC transmembrane type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_09115</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062684.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09115"/>
    <dbReference type="EnsemblBacteria" id="KPL77283">
        <property type="protein sequence ID" value="KPL77283"/>
        <property type="gene ID" value="ADN00_09115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="76"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="109"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="136"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="197"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="244"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="72"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL77283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="280" mass="31583" checksum="8C20658BC65C6307" modified="2016-01-20" version="1">MRESWEIIKKILLYFLLTGATLVMSFPLFWMISSSLKTLEETNAAGIVWLPENPSLNTYLAIFQNSDFLRAYFNTVFFVTLALVGTLFSIAVVAYAFSRIDWPGRNFVFFLMLATMMIPPQALIVPQYVFFNKLDWIGTFNPIIIPGYFAGGAAMVFLLRQSMSQIPKELDESAFVDGANHIQIFWEVVMPLVKAPLATVATFLFVGLWNSLLAPLMYLQTVDLYTLPVYVSTLYNINLTVQQWPTIMAAAVLTTVPLMVVFFFAQRFILEGVVVSGLKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XD87</accession>
    <name>A0A0P6XD87_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Beta-lactamase2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_06990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06990"/>
    <dbReference type="EnsemblBacteria" id="KPL78221">
        <property type="protein sequence ID" value="KPL78221"/>
        <property type="gene ID" value="ADN00_06990"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008800">
        <property type="term" value="F:beta-lactamase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030655">
        <property type="term" value="P:beta-lactam antibiotic catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045155">
        <property type="entry name" value="Beta-lactam_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000871">
        <property type="entry name" value="Beta-lactam_class-A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35333">
        <property type="entry name" value="PTHR35333"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13354">
        <property type="entry name" value="Beta-lactamase2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta-lactamase2" evidence="1">
        <location>
            <begin position="269"/>
            <end position="447"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="478" mass="52795" checksum="C4CF6B9996D58C89" modified="2016-01-20" version="1">MALILMALVLTVFELVQYSRIRSSFPPGMRIAGVPVGGLNQESAAERLVQAYGVPVELRYGDAVIQVKPQVVGFELKLDEMLAAADLQRITQPFWSAFWDYLWNQLPTPKSVPLSATISEERLRTYLKNEIAVRYDQPPEASIPLPGTTSFQSGNPGTVLDMDRAVVLIEDALRSPNARVVNLTYSQVKPPRPSLVNLEVLLKQIVDVSGFDGVVEMYMLDLKTREEMNFAYRNGEDLAPGIAFTAASTMKIPIMTSTFRRVSEPTPQTVLDQMALMIEQSENGPADRLMQNVLDLNLGPLQVTEDMQAIGLANTFIAGYFYPGAPLLQRFTTPANSRTDVNTEPDVYNQTTPADLGMLMDDLYQCANNGGGTLTAAYAGQVSQAECQQMLDFLSLNDIAVLIKAGIPEGTRIAHKHGWIIENDGYLHTMGNAAIVYSPAGDYVLVIFMYQPVQLVFDPANVLFANLSRAVYNYYNLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XF65</accession>
    <name>A0A0P6XF65_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_07435</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062351.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07435"/>
    <dbReference type="EnsemblBacteria" id="KPL78288">
        <property type="protein sequence ID" value="KPL78288"/>
        <property type="gene ID" value="ADN00_07435"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3310"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00413">
        <property type="entry name" value="HADHALOGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="234" mass="26135" checksum="185919232CD5A1EC" modified="2016-01-20" version="1">MRKQLRAAIFDMDGLMVDTERVARMGWKHAFRQFGIDLTDEEYLQFLGISTADVSAMITERFGGRVRFEDVYAVRQQHTHQFYEENGVPLKPGIVELLSFLESAGVERVVATSSTEEMARFRLQKAGLLEWFSFISSSDRVLRGKPAPDVYLTAIDWCGLQADECVALEDSEVGVRAAHAAGLRVIWVPDLAVPSEEAVGLAVHVAADLFDALQWIESWMAPTQQIGQTDPQVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XFA7</accession>
    <name>A0A0P6XFA7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_07745</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062406.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07745"/>
    <dbReference type="EnsemblBacteria" id="KPL78334">
        <property type="protein sequence ID" value="KPL78334"/>
        <property type="gene ID" value="ADN00_07745"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS" evidence="2">
        <location>
            <begin position="145"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="3">
        <location>
            <begin position="221"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="2">
        <location>
            <begin position="274"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="3">
        <location>
            <begin position="353"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="737"/>
            <end position="764"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL78334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="1715" mass="194577" checksum="EFBB83B679FB270E" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XFH9</accession>
    <name>A0A0P6XFH9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_14680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000035">
        <property type="protein sequence ID" value="KPL73582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063783.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000035.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL73582">
        <property type="protein sequence ID" value="KPL73582"/>
        <property type="gene ID" value="ADN00_14680"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="192"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL73582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="217" mass="23003" checksum="F09B43810180C780" modified="2016-01-20" version="1">MKPNTWRTILGVILVVLGAVSMAQIMGVFPEGSMFMTSIIALAFLGGGAAFLAVFLGNRANWWALIPGVILADLGLLIGFSEFVPGFDVISGAFFMAGLSLAFWLVYIFAPQNWWAIIPGGVLLTLAAIILLSDITDSDGFFVPAVLFLGMAATFAALALLRGHDAPVRWAWIPAGVLGVMGAMMALSATSLVGYVWPAALVLGGLYLIIRPTLRKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XFW7</accession>
    <name>A0A0P6XFW7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_04190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061706.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79080">
        <property type="protein sequence ID" value="KPL79080"/>
        <property type="gene ID" value="ADN00_04190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025234">
        <property type="entry name" value="DUF4177"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13783">
        <property type="entry name" value="DUF4177"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133036" evidence="1">
        <location>
            <begin position="20"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="109" mass="12187" checksum="91140CFBAC54557B" modified="2016-01-20" version="1">MKRKLILIFLLLAATLALAGCKKKAEEAPVYPQWEYTSLTVRCVFDGGSNNMVCRNFAEGSTDGINTILRNHGQQGWELVDVAVTGEGDGQYQTFIFKRYLGLPDEKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XG77</accession>
    <name>A0A0P6XG77_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ADH_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061922.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05240"/>
    <dbReference type="EnsemblBacteria" id="KPL78663">
        <property type="protein sequence ID" value="KPL78663"/>
        <property type="gene ID" value="ADN00_05240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ADH_N" evidence="1">
        <location>
            <begin position="50"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="576" mass="63113" checksum="B560C8204C6B285B" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGU5</accession>
    <name>A0A0P6XGU5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_03140</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000014">
        <property type="protein sequence ID" value="KPL79336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061505.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000014.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79336">
        <property type="protein sequence ID" value="KPL79336"/>
        <property type="gene ID" value="ADN00_03140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="350" mass="37372" checksum="21992F58B66EFAC5" modified="2016-01-20" version="1">MQTPVTHILPLTLIRRVRLLPAPGKVLVRAGQEVHAADVVAETASHQRHVLLDVRRALQLSADEDLKQVFDRKVGEKIQKGDLIAQKGGLFKRVLVSPEDGVILAVMGGQVLIEAVTPPTQIFAGFDGRVAEVIADQGVVIETHGALLQGVWGNNQIGNGLLISLAKSPADDLSSSLLDVSMRGAVLLAGTCSEASALEMARDIHLRGLILGSISAHLIPLAEKLEFPVMVLEGFGQIPISTPAFRILSTSEKREVCLNATRWDAFHGERPELVIPLPAQGEVAQDLAALQAGRKVRLTLAPWVGAVGSIEQMLPGQTALPNGLRAPAARVRLENGEVHTVPSVNLDVLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XH24</accession>
    <name>A0A0P6XH24_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_04285</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061722.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79093">
        <property type="protein sequence ID" value="KPL79093"/>
        <property type="gene ID" value="ADN00_04285"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038430">
        <property type="entry name" value="NDAH_ubi_oxred_su3_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="103" mass="10747" checksum="E25E9DBE61FC5E7E" modified="2016-01-20" version="1">MNVLLTPPIAFLIYIPLILLISLLGKALAPEHKADPAKISLYSSGEKAPTNTAAPGYAPFFLVAFFFAIIHLGILVLATGNLSSSSILYLAGLVLGLVALILG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XH46</accession>
    <name>A0A0P6XH46_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_02625</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000012">
        <property type="protein sequence ID" value="KPL79428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79428">
        <property type="protein sequence ID" value="KPL79428"/>
        <property type="gene ID" value="ADN00_02625"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="146" mass="16394" checksum="C23DD8907165A7B3" modified="2016-01-20" version="1">MKLDQSRLEYYITPEQAAKQLGLDLDSIYQLADEGKLQAAVMTDGSIGISQISVNNLLPKEALPEYQLNADLKGVPISINEAGRKYKLNTSTLTRWMQRGLIHQLGKEGRKTLLDEADVAYCARVYRQNSGQGKWAFDDSGRPYKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XHJ7</accession>
    <name>A0A0P6XHJ7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_13800</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the folylpolyglutamate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13800"/>
    <dbReference type="EnsemblBacteria" id="KPL74387">
        <property type="protein sequence ID" value="KPL74387"/>
        <property type="gene ID" value="ADN00_13800"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1337"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004326">
        <property type="term" value="F:tetrahydrofolylpolyglutamate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001645">
        <property type="entry name" value="Folylpolyglutamate_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018109">
        <property type="entry name" value="Folylpolyglutamate_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11136">
        <property type="entry name" value="PTHR11136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001563">
        <property type="entry name" value="Folylpolyglu_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01499">
        <property type="entry name" value="folC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01012">
        <property type="entry name" value="FOLYLPOLYGLU_SYNT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase_M" evidence="6">
        <location>
            <begin position="26"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="5">
        <location>
            <begin position="288"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR001563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL74387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="432" mass="47574" checksum="2D69691E08664E1B" modified="2016-01-20" version="1">MFNLERITELLERLGNPHKKYRVIHVAGTKGKGSVAAMIASALQMAGYRTGFFTSPHLVEYTERIKVNGVEISKDELVALVNEIKPQVEAVERITTFEITTALSFLYFARKNVDVAVVEVGLGGRLDATNVVQPLVSVITSLSMDHMAILGNSLEKIAFEKAGIIKPGRPVVVSPQKPEALETVARAAQERGSKMVLVGRDVRFAPWRSSLDGQTMLIWRAEEQDRMDAYLQEDGPQGWEPLEVFLPLLGQHQVQNAATAYAALQVAQEEGLVLTEADILKGFAYVVWPARFEVLRRDPPVVIDSAHNRDSALKLRLAIDDYFPGKDVVLLFGASEDKDVEGMFIELMPRVCQVVASESLHPRAMEAERIVKLAHQFGRPAVVVKPVENALAYALQQAGADAAVVVAGSMFMAAAVRELWFASLDVKKEFKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XHL8</accession>
    <name>A0A0P6XHL8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_02990</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000014">
        <property type="protein sequence ID" value="KPL79312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061477.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000014.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02990"/>
    <dbReference type="EnsemblBacteria" id="KPL79312">
        <property type="protein sequence ID" value="KPL79312"/>
        <property type="gene ID" value="ADN00_02990"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041202">
        <property type="entry name" value="BaeRF_family10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042226">
        <property type="entry name" value="eFR1_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="L30e-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18854">
        <property type="entry name" value="baeRF_family10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="366" mass="40579" checksum="8F6A98E936D7964C" modified="2016-01-20" version="1">MFDENDLRELLEFSGTDPILSIYLNTDPTMGNADAYRLRLRTMLKSVNAPKDVEAVELYMQHQYDWSGIGVVIFSCAAQKFFRAYPLEVPVRDHIHFGDLPSVQPLTDLLDSYGGYGVVLVDKQGARYFSFHMGQLHEQEGMLGDPVRHTKRGGASTIPGHRGGVAGRTRYTEEVIERNMKDAVEAAIQFFEENRIRRILIGGTDDNIAHFRSEMPKAWKSLVIGDFPMEMIASHAEVLQKAMQIGRVVERQREEKLVESAITAAAKGLNAVVGLQNVIPSVNEKRVQTLITGRGLQIPGHRCVSCHALLPANNQACPLCGGTLEPLEDILNAAINQVLRDGGDVQIVEVNDQLEQIGGVAAFLRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XHS1</accession>
    <name>A0A0P6XHS1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Putative fluoride ion transporter CrcB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">crcB</name>
        <name evidence="10" type="ORF">ADN00_02760</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Important for reducing fluoride concentration in the cell, thus reducing its toxicity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the CrcB (TC 9.B.71) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000013">
        <property type="protein sequence ID" value="KPL79376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061433.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000013.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02760"/>
    <dbReference type="EnsemblBacteria" id="KPL79376">
        <property type="protein sequence ID" value="KPL79376"/>
        <property type="gene ID" value="ADN00_02760"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1903425">
        <property type="term" value="F:fluoride transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00454">
        <property type="entry name" value="CrcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003691">
        <property type="entry name" value="CrcB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28259">
        <property type="entry name" value="PTHR28259"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02537">
        <property type="entry name" value="CRCB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00494">
        <property type="entry name" value="crcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="65"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="103"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL79376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="126" mass="13671" checksum="D19E657B0FDFB781" modified="2016-01-20" version="1">MKQIIVIGLGGFLGAIMRYGLSSFVQSALRNVNFPYGTLIVNLLGCFIIGLLSALAELRPFPPELRTFLMVGLLGAFTTFSTFSNESFNLLRGGENSLCLINIGMHLLAGLGMVWMGRLLAGQIWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XJG5</accession>
    <name>A0A0P6XJG5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glycos_transf_1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_16950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064237.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16950"/>
    <dbReference type="EnsemblBacteria" id="KPL71389">
        <property type="protein sequence ID" value="KPL71389"/>
        <property type="gene ID" value="ADN00_16950"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="274"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL71389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="407" mass="44920" checksum="9C25679E0926F440" modified="2016-01-20" version="1">MHILLTADGRSPITKRWIQGLLALQHRVSLISTFPCQPPAGVTDFHVLPVAFSSLGGSQALNRSTTPAAQPASRSRGAVSRFRDALQIARYWLGPLSLHFYGLRFNRVVKQLQPDIVHALRIPFEGMLAAYTPAGIPLAISIWGNDLTLHGNGSPLMRERTEQVIRKAQGLMADANRDIRLARQWGYPADFPWLVVPGSGGIDLVEITRAASPGSILEQFNIPVGVPLVINPRGFRPGSVRNDVFFASLPLALERCPEAVFLCPAMANQPEALQWVERYHLQKNVFLLPYLSQVELWSLFRHALASISISVHDGTPNSLLESMACGCFPIVGDIESLREWITPGVNGWLVPPDNPQALAEALTVVLHNPALRKSAAEINQKIIRDRAELNLMRSQIQVFYQRLAPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XJG7</accession>
    <name>A0A0P6XJG7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PAC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_17010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064248.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17010"/>
    <dbReference type="EnsemblBacteria" id="KPL71398">
        <property type="protein sequence ID" value="KPL71398"/>
        <property type="gene ID" value="ADN00_17010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAC" evidence="2">
        <location>
            <begin position="110"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL71398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="340" mass="38852" checksum="7A4102DC020A759C" modified="2016-01-20" version="1">MIRPQGNPGDSSLPAPSDPPVPSADQPIHTDCQWPPEFFTQLVENLPEAVLVTSLHNGRIVYCNPKAAQMHGCTSPQELIGSPGSQWMAPDSQEKMRQFALAFGDKSPSGALQLTLRRKDGTCFPAELEVSFLSGPTGKTRCCLNVIRDITWRCRLEENLEKYRAQLLDMVERQTKDLTLANQQLQNEIEQHCRTEIALKRSEHRYRSYLESQKELIARFAENGRLVYANPAFRAFFPNVESYSLAEIQSKLIHPSQKDQIQSLFENCQPPFQTVFLANTRTPSGYRWIEWNIQSVESGHSQSVEYQCVGRDVTRQKELDEEKEELIRGLREISQHIYTI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XJK4</accession>
    <name>A0A0P6XJK4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Fumarate hydrolyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_17370</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I fumarase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71453.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064316.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17370"/>
    <dbReference type="EnsemblBacteria" id="KPL71453">
        <property type="protein sequence ID" value="KPL71453"/>
        <property type="gene ID" value="ADN00_17370"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.538"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016836">
        <property type="term" value="F:hydro-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004647">
        <property type="entry name" value="Fe-S_hydro-lyase_TtdB-typ_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036660">
        <property type="entry name" value="Fe-S_hydroAse_TtdB_cat_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05683">
        <property type="entry name" value="Fumerase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117457">
        <property type="entry name" value="SSF117457"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00723">
        <property type="entry name" value="ttdB_fumA_fumB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fumerase_C" evidence="3">
        <location>
            <begin position="16"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF05683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL71453.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="219" mass="23836" checksum="9C978F23EDA702EA" modified="2016-01-20" version="1">MNDRLLPGEQGLRLPLSDEQVRVLRVGQAVRLSGRLVTARDAAHQWLVRTFIQPGAHPSADELAVLADLRRILAGGAIYHCGPVVAQQSDGSYRFLAAGPTTSAREEPYQADVMRFFNVKAVIGKGGMGARTLRACQQTPAVYLHAVGGAAALIAQTVRRVETVYQLEFGVPEALWVIEVEDFPAVVTMDALGASLHEEVRRASQAELDRLLGKTEERN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XJW3</accession>
    <name>A0A0P6XJW3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5 7">30S ribosomal protein S9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsI</name>
        <name evidence="9" type="ORF">ADN00_12450</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063340.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12450"/>
    <dbReference type="EnsemblBacteria" id="KPL76139">
        <property type="protein sequence ID" value="KPL76139"/>
        <property type="gene ID" value="ADN00_12450"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3971"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00532_B">
        <property type="entry name" value="Ribosomal_S9_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000754">
        <property type="entry name" value="Ribosomal_S9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023035">
        <property type="entry name" value="Ribosomal_S9_bac/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020574">
        <property type="entry name" value="Ribosomal_S9_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21569">
        <property type="entry name" value="PTHR21569"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00380">
        <property type="entry name" value="Ribosomal_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00360">
        <property type="entry name" value="RIBOSOMAL_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="106"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="116"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016789"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL76139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="131" mass="14502" checksum="156F0A193F7BFD36" modified="2016-01-20" version="1">MSVQYFEGVGRRKESTARVRVMSGSGSIVVNEKPIEDFFTRLGDKEMIESVLNVLGDESRKFDVTVKVMGGGVTGQTGAVVLGLARALVKYDNTLTPLLRKGGFLTRDPRVKERKKPGLKRARKAPTYTKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XJX1</accession>
    <name>A0A0P6XJX1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein translocase subunit SecY</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">secY</name>
        <name evidence="11" type="ORF">ADN00_12505</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may move independently.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the Sec protein translocase complex. Heterotrimer consisting of SecY, SecE and SecG subunits. The heterotrimers can form oligomers, although 1 heterotrimer is thought to be able to translocate proteins. Interacts with the ribosome. Interacts with SecDF, and other proteins may be involved. Interacts with SecA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 10">Belongs to the SecY/SEC61-alpha family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063350.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12505"/>
    <dbReference type="EnsemblBacteria" id="KPL76148">
        <property type="protein sequence ID" value="KPL76148"/>
        <property type="gene ID" value="ADN00_12505"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3982"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0065002">
        <property type="term" value="P:intracellular protein transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043952">
        <property type="term" value="P:protein transport by the Sec complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01465">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026593">
        <property type="entry name" value="SecY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002208">
        <property type="entry name" value="SecY/SEC61-alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030659">
        <property type="entry name" value="SecY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023201">
        <property type="entry name" value="SecY_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10906">
        <property type="entry name" value="PTHR10906"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00344">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004557">
        <property type="entry name" value="SecY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103491">
        <property type="entry name" value="SSF103491"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00967">
        <property type="entry name" value="3a0501s007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00755">
        <property type="entry name" value="SECY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="73"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="118"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="155"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="189"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="216"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="267"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="319"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="376"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="400"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL76148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="443" mass="48568" checksum="98C29250C45D06CB" modified="2016-01-20" version="1">MKRSAWRYLWTSEDIRKKLLITLGLLILYRLAANIPVPGIDRLALSQLTQAGGAAGNLVGLLDLLSGGTVSRFSVLAMGVYPYITAQIILQLLMPIIPALEAKMKENPREGQKWMEKWTVILTVPMALLSAVGQINIFNSIAGAPILQIGFSSDLLLSTATALLSMIAGTMFGIWLGQLISEYGIPNQGLSLIIFAGIVSRLPESLNAILRDQQRGWWLAIIMLVILALTIFAIVFVQQGRRNVPVMFPGRRIGNRMSMPVRSNLPLMVNMAGMIPLIFAQSMLTFPAIVASFFLASKTEWVANLAKGVSDVFGGNSPWYSLMYFVMVVLFTFFYTDVLFAQQNYGDNLKKQGAQIPGVTRGGPTQRYLTKVQRRITLPGALFLGFVAVLPFILGELLNIQQAGLSLISAAGMLIVVGVVRDTFNIIDTELKLHGYDDSLIKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XK26</accession>
    <name>A0A0P6XK26_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_12990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000028">
        <property type="protein sequence ID" value="KPL75301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063451.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000028.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12990"/>
    <dbReference type="EnsemblBacteria" id="KPL75301">
        <property type="protein sequence ID" value="KPL75301"/>
        <property type="gene ID" value="ADN00_12990"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013411">
        <property type="entry name" value="CRISPR-assoc_RAMP_TM1809"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005537">
        <property type="entry name" value="RAMP_III_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03787">
        <property type="entry name" value="RAMPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02581">
        <property type="entry name" value="cas_cyan_RAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL75301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="302" mass="32218" checksum="957116FC00F79224" modified="2016-01-20" version="1">MSAIADQSVEIEFYGHDQAINLYCFSGTLTLTHAMHIGSGRGDLTTDALVVTDGAGKPIIPGSSFRGLFRSHIERLLAGLNAAGVTTLWACQLYDASPLGICIGNQVNQESKDKLKELVNRAKTSGLPAIWNDLPKALCSVCQLFGASAVWASKIKFSDLNLLNEPLTQIRHGVGIHRDSGTAAPGVKYDKLVVEAGREFKFEAIAENLTEQDKRLLALGFQAILNGTAALGGSTGRGLGDFALTGGDVSWVDCKNKSDLVNYLLKKEYSGSQSLDDFVNETLNTWLAPQENGGGDAQTAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKJ7</accession>
    <name>A0A0P6XKJ7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GH16 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_16335</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16335"/>
    <dbReference type="EnsemblBacteria" id="KPL72047">
        <property type="protein sequence ID" value="KPL72047"/>
        <property type="gene ID" value="ADN00_16335"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3707"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="GH16"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH16" evidence="1">
        <location>
            <begin position="38"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="285" mass="31969" checksum="4AB0166448E30DCC" modified="2016-01-20" version="1">MGKNYLIRRSFLIFLFSLNFGLLSGCQLADGRQAIAVDTTPIIPPEGWELVWHDEFDDPAINPENWTFDLGGGGWGNGEMQIYTNKSDNARVEDGNLVIEARKEPNENGGFSFTSARLKTQGLQTFQYGRIEARIKVPAGAGFWPAFWMLGSNFPEVGWPDCGEIDIMEYVGKDPTNILGTMHGPGYSGALGLSGWKRQTENIADDFHVYAIEWDTDEIKWFFDGEQYSAYTREDVGNREWVFDQPFFMILNLAVGGTLGGLVSPETVFPSQVLVDYVRVYQVSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKS7</accession>
    <name>A0A0P6XKS7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_01630</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061217.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01630"/>
    <dbReference type="EnsemblBacteria" id="KPL80571">
        <property type="protein sequence ID" value="KPL80571"/>
        <property type="gene ID" value="ADN00_01630"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1086"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001585">
        <property type="entry name" value="TAL/FSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018225">
        <property type="entry name" value="Transaldolase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10683">
        <property type="entry name" value="PTHR10683"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00923">
        <property type="entry name" value="TAL_FSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01054">
        <property type="entry name" value="TRANSALDOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL80571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="215" mass="23386" checksum="23EAF41532F66016" modified="2016-01-20" version="1">MKAFYLDSANVEQAKKVAEWGWVKGITTNPSLLTRSEYPPETTLLNLAAAMPGVPVFYQLTAPDLDNMLREADRARQLLQERLVLKIPATTAGLAACARLSPHQPVAVTTVYHTAQALAANAAGAQYLIFYHDRALRRLEDGHQLAAELVRALAGTSTQIIAASIKSLEEIYAVRMAGITHLTVPFEVLAQIGAYEPTLKDVEAFQETGSGLLEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XL65</accession>
    <name>A0A0P6XL65_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_10255</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062908.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10255"/>
    <dbReference type="EnsemblBacteria" id="KPL76961">
        <property type="protein sequence ID" value="KPL76961"/>
        <property type="gene ID" value="ADN00_10255"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2516"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="8"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="44"/>
            <end position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL76961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="337" mass="37763" checksum="20CCFE5761D968A5" modified="2016-01-20" version="1">MENKETLLQVRNLTVTYHTRLGPVSAVSDVSFDVYRGEILGLVGESGCGKSTMGKALMRLIAPPGEISEGQIILSGEDILKYDENQLREMRGAHVSMIFQDPMTSLNPVQRIDQHGIEAIQVHEPKTKIEQALERVSKLFERLGIQKRRLTDYPHQLSGGMRQRVMIGLGLALNADLIIADEASTSLDVIVEAKLADQLREIRDEFGVTLMVITHNIALVAELADRIAVMYAGRMVELGDVYEVFDNPLHPYTQGLLASVPNIILNEREELYKMPGEPPNLTHPPSGCRFHPRCPKAMDICSRYQPSFEEVTPGRFVHCWLYQDHPEKETPTLKVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XLU6</accession>
    <name>A0A0P6XLU6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_09095</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062682.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09095"/>
    <dbReference type="EnsemblBacteria" id="KPL77281">
        <property type="protein sequence ID" value="KPL77281"/>
        <property type="gene ID" value="ADN00_09095"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4053"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003680">
        <property type="entry name" value="Flavodoxin_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02525">
        <property type="entry name" value="Flavodoxin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin_2" evidence="1">
        <location>
            <begin position="1"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="FMN_red" evidence="2">
        <location>
            <begin position="196"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="464" mass="53025" checksum="0B5E350FF5F9D873" modified="2016-01-20" version="1">MKILVLNGSPKGGISVTMQYVNYLQKIHPEVSFESVNIAQQIRKIETDPQEFDKIISRVRLADGVLWAFPLYILIVHAHYKRFIELVNERGVMDAFAGKYAASLFTSIHFFDHTAHNYIHGICDDWGMRYIEAFSPDMVDLLEEKGRTQLKQFGQRFLHAIESRALTQRQYPPLSQREFLYKASLISAMLDAGEKKVVIVYDGGRPGSNIEEMVKTCQAAISGNVQVIDLNQVEIKSSCQGCLHCGYNNVCSFEGKDSFTEFYRTTIMTADVLVYAGTVVDRYLSSRWKTFFDRSFFNTHTPVLIGKQLAYVISGPVSQLPNLQEILYGYAEFQQANIVGLVSDEYGDASEIERLLQQLMVSAVQMAEARATRPMTFLGEGGLKVFRDDIWGRLRMVFRADHHAYQRLGFYKTFPQRNWLSRITNSIMLGLLRIPPFRKGFNQQITRQMVQPAQKVIESANLNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XLV0</accession>
    <name>A0A0P6XLV0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">30S ribosomal protein S5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rpsE</name>
        <name evidence="11" type="ORF">ADN00_12520</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Located at the back of the 30S subunit body where it stabilizes the conformation of the head with respect to the body.</text>
    </comment>
    <comment type="function">
        <text evidence="7">With S4 and S12 plays an important role in translational accuracy.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the 30S ribosomal subunit. Contacts proteins S4 and S8.</text>
    </comment>
    <comment type="domain">
        <text evidence="7">The N-terminal domain interacts with the head of the 30S subunit; the C-terminal domain interacts with the body and contacts protein S4. The interaction surface between S4 and S5 is involved in control of translational fidelity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 9">Belongs to the universal ribosomal protein uS5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063353.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12520"/>
    <dbReference type="EnsemblBacteria" id="KPL76151">
        <property type="protein sequence ID" value="KPL76151"/>
        <property type="gene ID" value="ADN00_12520"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3985"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01307_B">
        <property type="entry name" value="Ribosomal_S5_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000851">
        <property type="entry name" value="Ribosomal_S5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005712">
        <property type="entry name" value="Ribosomal_S5_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005324">
        <property type="entry name" value="Ribosomal_S5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013810">
        <property type="entry name" value="Ribosomal_S5_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13718">
        <property type="entry name" value="PTHR13718"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00333">
        <property type="entry name" value="Ribosomal_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03719">
        <property type="entry name" value="Ribosomal_S5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01021">
        <property type="entry name" value="rpsE_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50881">
        <property type="entry name" value="S5_DSRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 7 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="S5 DRBM" evidence="10">
        <location>
            <begin position="11"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL76151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="174" mass="18705" checksum="C0B85B699F4AF4B6" modified="2016-01-20" version="1">MDNFQPMEDQLDERVIEIARVAKVVKGGRRFQFRVAVVVGDNNGNVGLGIGKANAVPDAMRKASERARKNMHKVALSGTTISHEVMGRVAGARVLLKPASRGTGVIAGGSTRAVLEAAGVRDILTKSLGSTNVLNVVKATFQALESIKDPKVEAAHRGKPVEELLPFWERRKNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XLW2</accession>
    <name>A0A0P6XLW2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GP-PDE domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_11680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11680"/>
    <dbReference type="EnsemblBacteria" id="KPL76169">
        <property type="protein sequence ID" value="KPL76169"/>
        <property type="gene ID" value="ADN00_11680"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3811"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008081">
        <property type="term" value="F:phosphoric diester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030395">
        <property type="entry name" value="GP_PDE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017946">
        <property type="entry name" value="PLC-like_Pdiesterase_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03009">
        <property type="entry name" value="GDPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51695">
        <property type="entry name" value="SSF51695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51704">
        <property type="entry name" value="GP_PDE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GP-PDE" evidence="1">
        <location>
            <begin position="8"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="252" mass="27822" checksum="7388AA291E0D5A5C" modified="2016-01-20" version="1">MLYTLPKPVIFGHRGACAHAPENTLASFRLAFEQGADAIELDAKLSRDGEVVVFHDPTLDRTTNGTGCVDSKSLAELRELDAGSHFSEQFRGEKIPLLLEVLEEFGKTRYINIELTNYTSPNDELVEKAAALVNSMGLGERILFSSFSAQNLKKVRQLVPEAETGMLALRGLAGFIARNISGRQVAPHAVHPYLTDASQQWIEIAHRQGRRVHVWTVNRPVDLKDLFDWGADGVFTDDPALAVDLRGQMKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XM94</accession>
    <name>A0A0P6XM94_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_18415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064515.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70037">
        <property type="protein sequence ID" value="KPL70037"/>
        <property type="gene ID" value="ADN00_18415"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="157" mass="17365" checksum="4EDCB9B64DE3C2DE" modified="2016-01-20" version="1">MMDTQFTQSRPPSPSPRHRSQVLWQIAVPLGVFILGILALAVLSVIRSSTDFEAGLHWANISAIFIITPILTFSFITLIILALLIYGLARLLKVIPAASLKVWSYFEIAKNYVRLASDQVTRPIVSANAWARQGQTLAGRVFHPRKAGQPSSEKVDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XMY0</accession>
    <name>A0A0P6XMY0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HTH gntR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_11000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11000"/>
    <dbReference type="EnsemblBacteria" id="KPL76581">
        <property type="protein sequence ID" value="KPL76581"/>
        <property type="gene ID" value="ADN00_11000"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="4">
        <location>
            <begin position="11"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL76581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="234" mass="25860" checksum="E9582ED4F3310136" modified="2016-01-20" version="1">MAINATQKDRKSLSLQAYERLRADILTCSILPGEQIAQASLAEKYQLGTTPVREALQRLAQEGLVRAIPRFGYEVSPITLADVEEMYELRAVIEPDAARLAAQRATRQQLDAILASADFSYTYGDHPSYTRFLGLNTAFHSTIASASGNRRLAELVASVLDELLRVFHLGLDLKDSADEMRSQHLELAEACAARDAQRAAELALAEIESSRARVMAALQQQFSTRGELSPVERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XN18</accession>
    <name>A0A0P6XN18_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_08115</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062485.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08115"/>
    <dbReference type="EnsemblBacteria" id="KPL77839">
        <property type="protein sequence ID" value="KPL77839"/>
        <property type="gene ID" value="ADN00_08115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="SSF54106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LysM" evidence="1">
        <location>
            <begin position="73"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="505" mass="55378" checksum="041341FB35DF7564" modified="2016-01-20" version="1">MKFNLPYWFPQRLRHNGLKILLAIPVLISACAPSSPRISFDLLQEQTEQAAQAESISPTPLPTRPAYEPGELVEYSVQPGDTLPALAVRFNTTEAEIREANPILPAELSTLPPGMPMQIPIYYQPLWGSSYQILPDRLFGYGPAQVGFDTVEFVNSQPGWLKDYTGVAGGLPKSGGELVEIVATNFSISPRLLLALIEYQTGGLTNPQQPDPDNPYVLGYEDRKHPGLYQQLLWAANFLNDKFYRYRLGKLTSFEHLDGRLERPDPWQNAATVALQVYFSTMLDKDQYFTATHGEGLQKTYANLFGDPWADTTPHIPGSLQQPAFRLPFLPGKAWAYTGGPHTGWGSDQPYAAIDFAPPNVVGGCSPTEEWAIAMADGTIVRTDTGVAVLDLDGDQDERTGWVIFYLHLSTKTIPPVGTALKAGDPIGQPSCDGGTSTGTHVHIARKYNGEWVPADSPVPFNMEGWITKDGKAPYQGLLVQYGRTVIACDCSNQESLVQSLGPLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XNV7</accession>
    <name>A0A0P6XNV7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF5655 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062870.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10055"/>
    <dbReference type="EnsemblBacteria" id="KPL76928">
        <property type="protein sequence ID" value="KPL76928"/>
        <property type="gene ID" value="ADN00_10055"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025629">
        <property type="entry name" value="DUF4287"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043714">
        <property type="entry name" value="DUF5655"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14117">
        <property type="entry name" value="DUF4287"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18899">
        <property type="entry name" value="DUF5655"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF5655" evidence="1">
        <location>
            <begin position="82"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF18899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="191" mass="21059" checksum="1024EF3083B3E67B" modified="2016-01-20" version="1">MPPRSPQEMMAAVAANLQQRTGRSLSEWVELVNASGIDPLDQKAVRNWLKTQHGVPQNSQWEIAETAACAAGWVRPSVEGYIDSQYTGPKAHLRPLFDRLREIIEALGDDVRAEGRSTYTPFVRRRQFAAVAAASRARIEVGLRFTNPPASPRLSPAKAPGQATHKLSVSSLEEIDEEVAALLRESYEQNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XP68</accession>
    <name>A0A0P6XP68_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_10840</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063015.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10840"/>
    <dbReference type="EnsemblBacteria" id="KPL77047">
        <property type="protein sequence ID" value="KPL77047"/>
        <property type="gene ID" value="ADN00_10840"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.760.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036909">
        <property type="entry name" value="Cyt_c-like_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133157" evidence="2">
        <location>
            <begin position="21"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="143" mass="15327" checksum="E3BA682ED120131C" modified="2016-01-20" version="1">MKKKFVTAAVLMSIAVLVLAACAPAAQPAAETQPPAASQPPAAEEPTQPPAASQPPVAEEPAPTQAMPEPTAAQMEEPAAAEIDVEALIIEKVAGNHDVERIFNAVKTREEWEETLDRMIGYGAQISEEEKQIMIDYLLSRQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQ27</accession>
    <name>A0A0P6XQ27_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_17260</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064296.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL71436">
        <property type="protein sequence ID" value="KPL71436"/>
        <property type="gene ID" value="ADN00_17260"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL71436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="361" mass="40951" checksum="2D887E2F76ADBC88" modified="2016-01-20" version="1">MKLVFVYVSPQDASPGMEWRFIHLARVLNRRGDHPVYCINLNDFLQESEAVRDVCAEADLILIQAEPSHEISLAIQHWKAQGKVVLIDLEDRSNLSRTAQAQPGGQHCDCLVNGTSTEAIETALRLSDGAILPFASSMLRWNGHTRYHVIPSYIDLENLMSMNRVEHDGIVVGWHHGLVRGQPVAEEWLAGLLERVSQSRPNVRWMPLAAASGDFKAWPKELTERFLLDESRSLVWPRPLGWVDIGLVPQFDVAVESLARINTLEYMALKIPWIGSETGNNFDLRPHGWLVNNANGSWERILMDMIDHIHIYQRDSVWGPYVYGISQGAEENLDRTMTTFWKVLESAGVERESGYGQAYTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQV2</accession>
    <name>A0A0P6XQV2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_04885</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061831.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79183">
        <property type="protein sequence ID" value="KPL79183"/>
        <property type="gene ID" value="ADN00_04885"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="85"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="114" mass="12281" checksum="E7D53CB0C94BF30C" modified="2016-01-20" version="1">MPNPRKPSQTRSSHRPAGVTRQALAILGLLILLTALAWTSPFQTQPTPAPANTTALAATPDGTLTPSVTPLPEEWLQSYRNTNEVVLVGVLLVLIVVIGTFGAIWRANRKRPAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XR48</accession>
    <name>A0A0P6XR48_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Sugar-bind domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_13300</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SorC transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063510.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000031.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74817">
        <property type="protein sequence ID" value="KPL74817"/>
        <property type="gene ID" value="ADN00_13300"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007324">
        <property type="entry name" value="Sugar-bd_dom_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04198">
        <property type="entry name" value="Sugar-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sugar-bind" evidence="2">
        <location>
            <begin position="65"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL74817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="321" mass="34707" checksum="A61B19A97C6EF3E0" modified="2016-01-20" version="1">MPRLDPKQELRLMAKVSRLYYNEGLTQDTIVEKLNLSRAKISRLLQQARDVGIVTITVNAPAGTYSDLEEQIEARYGLREVIVVDVADPDSQVVVNQELGIAAANYLNRIIKNGDSIGFSWGTTLNQVVSYIQAQSLPDAQVVQIIGGLGPPESEFHATDLCRRAAQHLGCRLTLLPAPGIVDNQQVKEVILSDSHVQKAFHEFCSLNIAFVGIGAPTPSSVVMRDGSILNQQDLERLQSQGAVGDIALRFFDSSGTPIYSDLDTRVIGISLEQLSCIERVVGISGGVSKTAAIQGALAGKLVDVLITDQLTARRLANPHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XRK0</accession>
    <name>A0A0P6XRK0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH cro/C1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_02575</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000012">
        <property type="protein sequence ID" value="KPL79421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061397.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000012.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02575"/>
    <dbReference type="EnsemblBacteria" id="KPL79421">
        <property type="protein sequence ID" value="KPL79421"/>
        <property type="gene ID" value="ADN00_02575"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13443">
        <property type="entry name" value="HTH_26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="23"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="80" mass="9102" checksum="FE8E8CCCA2B9B516" modified="2016-01-20" version="1">MPGKIVNHFRILLAQKATKQQQSIALMDVQRETGIAWSTLNSWANNQLTRYDAPVIMALCEYFDCQVGDLLVFEKEISAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XSZ7</accession>
    <name>A0A0P6XSZ7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Purine nucleoside phosphorylase</fullName>
            <ecNumber evidence="3">2.4.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Inosine-guanosine phosphorylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_07105</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">The purine nucleoside phosphorylases catalyze the phosphorolytic breakdown of the N-glycosidic bond in the beta-(deoxy)ribonucleoside molecules, with the formation of the corresponding free purine bases and pentose-1-phosphate.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 3">Purine metabolism; purine nucleoside salvage.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the PNP/MTAP phosphorylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.1" evidence="3"/>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062288.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07105"/>
    <dbReference type="EnsemblBacteria" id="KPL78236">
        <property type="protein sequence ID" value="KPL78236"/>
        <property type="gene ID" value="ADN00_07105"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00606"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004731">
        <property type="term" value="F:purine-nucleoside phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd09009">
        <property type="entry name" value="PNP-EcPNPII_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011270">
        <property type="entry name" value="Pur_Nuc_Pase_Ino/Guo-sp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011268">
        <property type="entry name" value="Purine_phosphorylase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11904">
        <property type="entry name" value="PTHR11904"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000477">
        <property type="entry name" value="PurNPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="SSF53167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01700">
        <property type="entry name" value="PNPH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01697">
        <property type="entry name" value="PNPH-PUNA-XAPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PNP_UDP_1" evidence="5">
        <location>
            <begin position="27"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphate binding" evidence="4">
        <location>
            <begin position="84"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="33"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>a purine D-ribonucleoside</name>
            <dbReference type="ChEBI" id="CHEBI:142355"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>a purine D-ribonucleoside</name>
            <dbReference type="ChEBI" id="CHEBI:142355"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006751"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000477-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL78236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="278" mass="30160" checksum="3A3EE61F1258E680" modified="2016-01-20" version="1">MSEYITLEQIDEAVKTIEARTQYRPKLAMILGSGLNDLANAIDNADIIPAEEIPNWPKSTVQGHMGRLVIGTLAGKEVLVMQGRSHYYEGYSMAQVTFPVRVMNRMGVNTLFVTNAAGAVNQDYAPGDVMLIVDHINLIGMGGLSPLRGPNLDVFGERFPDMSQPYDRELCDLARGAAKKNGIRLHEGVYTILAGPSFESPAELRYLKGIGTDAVGMSTVPEVIVARHGKMRVLGISGISNKANLDGSTMTTHEEVLEAGHIIAPKIKDIFLGVLENL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XT67</accession>
    <name>A0A0P6XT67_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_07450</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062354.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07450"/>
    <dbReference type="EnsemblBacteria" id="KPL78291">
        <property type="protein sequence ID" value="KPL78291"/>
        <property type="gene ID" value="ADN00_07450"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="229" mass="24572" checksum="92F07DE24BC00C32" modified="2016-01-20" version="1">MNNPNPIPVTTVNADAILFDLDGVLIDSTTSIVQHWREWAEQHNLNLDFILQNAHGMRTIETMRIVAPHLNVEEEALRFTANEITDTAGVVSIEGARSLLTALPPASWAIVTSCGLDLVQARMGATGLPIPAVLVTADDVQNGKPSPEPYLAGARRMGLPVERCVVIEDAPAGIIAGKKAGMRVIAVASTHSPEELLASGADFVVAKLQNIHVTRSNYHSRLTIHLEGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XT79</accession>
    <name>A0A0P6XT79_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_07530</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062367.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07530"/>
    <dbReference type="EnsemblBacteria" id="KPL78300">
        <property type="protein sequence ID" value="KPL78300"/>
        <property type="gene ID" value="ADN00_07530"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3332"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032583">
        <property type="entry name" value="DUF4914"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16260">
        <property type="entry name" value="DUF4914"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="621" mass="69414" checksum="2E5609609F1A6C0C" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUF4</accession>
    <name>A0A0P6XUF4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Chemotaxis protein CheY</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_10610</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062972.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10610"/>
    <dbReference type="EnsemblBacteria" id="KPL77012">
        <property type="protein sequence ID" value="KPL77012"/>
        <property type="gene ID" value="ADN00_10610"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="6"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="150"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL77012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="220" mass="23740" checksum="3BCE3712FC30494B" modified="2016-01-20" version="1">MNQPIRILIADDHLIVREGMRLILETEADFECVGEAADGAQALRMAAELQPDVVLMDLRMPVMDGLTAIERLHAEQPRIAVVILTTYNEDDLISRGLRAGARGYLLKDTGREKLFATIRAAARGDLLLDPDLMARLLAYSGAGQPKASSTGAEEAGLTERELEVLAAAARGATSKEIALRLNITERTVKAHLTNVYTKLGVDSRAGAVTAAVQRGLLKLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUS4</accession>
    <name>A0A0P6XUS4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">GTP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_03305</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the GPN-loop GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061539.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03305"/>
    <dbReference type="EnsemblBacteria" id="KPL78940">
        <property type="protein sequence ID" value="KPL78940"/>
        <property type="gene ID" value="ADN00_03305"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.8"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004130">
        <property type="entry name" value="Gpn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03029">
        <property type="entry name" value="ATP_bind_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL78940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="179" mass="20140" checksum="3525A442DB7534ED" modified="2016-01-20" version="1">MQTVKIVVTGPFSAGKTEFIRTVSEIDVVSTERKITAEAERIKQTTTVAMDFGRITVDDDLVLYLFGTPGQKRFDFMWEILSEGMLGFIVVVDSNRPETFREARSILQTFKAYAPTPYVVAANKQDSPDAWDLEDMRVALRLDPDVKLLPCVALDKEKVKTVLLELLFTIQTLMESGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XXZ6</accession>
    <name>A0A0P6XXZ6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pyrroline-5-carboxylate reductase</fullName>
            <shortName evidence="2">P5C reductase</shortName>
            <shortName evidence="2">P5CR</shortName>
            <ecNumber evidence="2">1.5.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">PCA reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">proC</name>
        <name evidence="5" type="ORF">ADN00_07235</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>L-proline + NAD(+) = 1-pyrroline-5-carboxylate + 2 H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:14105"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15893"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="EC" id="1.5.1.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>L-proline + NADP(+) = 1-pyrroline-5-carboxylate + 2 H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:14109"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15893"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="EC" id="1.5.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-proline biosynthesis; L-proline from L-glutamate 5-semialdehyde: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the pyrroline-5-carboxylate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.2" evidence="2"/>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062311.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07235"/>
    <dbReference type="EnsemblBacteria" id="KPL78255">
        <property type="protein sequence ID" value="KPL78255"/>
        <property type="gene ID" value="ADN00_07235"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3267"/>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00361"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004735">
        <property type="term" value="F:pyrroline-5-carboxylate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01925">
        <property type="entry name" value="P5C_reductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028939">
        <property type="entry name" value="P5C_Rdtase_cat_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029036">
        <property type="entry name" value="P5CR_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000304">
        <property type="entry name" value="Pyrroline-COOH_reductase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11645">
        <property type="entry name" value="PTHR11645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03807">
        <property type="entry name" value="F420_oxidored"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14748">
        <property type="entry name" value="P5CR_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000193">
        <property type="entry name" value="Pyrrol-5-carb_rd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00112">
        <property type="entry name" value="proC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F420_oxidored" evidence="3">
        <location>
            <begin position="7"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="P5CR_dimer" evidence="4">
        <location>
            <begin position="164"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF14748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL78255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="280" mass="30331" checksum="ACE9152D92AD4613" modified="2016-01-20" version="1">MNEYPNIAVIGPGAMGEAIIAGLLRNGLKTPKQIYASGPLIDRGKEIGERYGVHSIHDNKEAVKSAGVVILSVKPQTINQVLADLHGCIPQDALVFSIVAGVTIEMISRGLAHDAVVRAMPNTPAQIGEGITVWTDSAAVNDRQRELARMVLSALGEEVYVDDESYLDMATALSGSGPAYVFLFMEAMIDAGVHLGFSRRISEELVMQTIRGSVNYFDKKRHHPAELRNEVTSPAGTSAAALYYLEKAGFRTAISRAVWAAYERCVELGKGRNSQMPENM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XYC6</accession>
    <name>A0A0P6XYC6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_14170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063681.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000033.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74142">
        <property type="protein sequence ID" value="KPL74142"/>
        <property type="gene ID" value="ADN00_14170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL74142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="186" mass="21441" checksum="FE649BCC7C15C9E2" modified="2016-01-20" version="1">MSHQLNLESVIEKLVLLQHFAHGSKEYCRERLAGSEKDIGDAEFDDYWVWAKGLVSSYILECSIRVRVLLDTVSDKPEAKEIAKIDIESISGLTLGKVVKGDFDLSIRESCNKIIHAKKVFPVWQNAFEKDVEFRYWSGEFNLIGTKGKDEWEVILHIASWARAVEKFLTNIDLQDLIIYVGQDWY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y1R7</accession>
    <name>A0A0P6Y1R7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_12890</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063428.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000027.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL75532">
        <property type="protein sequence ID" value="KPL75532"/>
        <property type="gene ID" value="ADN00_12890"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL75532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="355" mass="39588" checksum="A84884BF4A18CEDF" modified="2016-01-20" version="1">MNVYEDKYLRDKISRIIARQKEGKVVIAAYKDGSGLPTREDLGQWLARAAYPYDYAVGSAGFLNYDSELGAYLYTAKPGVKQPEVISHYQPLSLAEAELIVQQRMARIHAGDTAVTFSGVHTWKGMYEILREINEELARVNAGIVVWKITPREGSGQEPAKRLFTGAVPRLRNGQAMGHVTGYAFDDDHALAYMGLVGYKTSLESLRITLMTGKSLQMIQDGVGDHTLIPTDKYEQAWQAMPEYTSHHAAFVSRLATPGKWEPEDLVAYLLVFRDVSDPSAELIRLFTERLKEALEIPILDAWASVLWEQASDCKYVQKMNVGGDCTLGAKIDLQADWQELLSNLLAEKVIALTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y1Y9</accession>
    <name>A0A0P6Y1Y9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_03595</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061597.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78987">
        <property type="protein sequence ID" value="KPL78987"/>
        <property type="gene ID" value="ADN00_03595"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="165"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="194" mass="21040" checksum="E07B9CA4E16BF871" modified="2016-01-20" version="1">MLTIHVLPVFFLIASSILILLAHRWRNFLIGLAVQYIGIFWLVALEWPVGLAAVKLVVGWMAGAMLAANHLEEEVVESDPLSNVSGKIFRVLAAVIVWVLMFSIAPEIQRWIPGRDEMLWGGLVLVGTGLLQLGLFNTPLRVSLGLLTVLGGFEVLYAVVETSILVTGLLAMANLGIALVGAYLISVPELEVSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y2M9</accession>
    <name>A0A0P6Y2M9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_04860</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="8">Binds 2 divalent metal cations per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase M42 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061827.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04860"/>
    <dbReference type="EnsemblBacteria" id="KPL79179">
        <property type="protein sequence ID" value="KPL79179"/>
        <property type="gene ID" value="ADN00_04860"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008007">
        <property type="entry name" value="Peptidase_M42"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023367">
        <property type="entry name" value="Peptidase_M42_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05343">
        <property type="entry name" value="Peptidase_M42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001123">
        <property type="entry name" value="PepA_GA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="208"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="176"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="209"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="315"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR001123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001123-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001123-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL79179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="352" mass="37983" checksum="160FE1DF4B71361C" modified="2016-01-20" version="1">MQETTRHLKKWISLPGLSGAEAPLREAIQAAWKPLTDEISASAMGSLHALKKGSGPSPRPSIMVSTHMDAIGLMVSAVEQEWLRVTQIGWVDARILPGQPVLVHAQRDLPGVVVQPAAHLLPPSEQDGPVSLDQLLVDTGLPAAELQELVSVGDFISFSQPWMDLAGETLAGHSLDNRASVAALTHCLEILQTREHAWDVWAVASVQEEIGHFGAATSAYQLRPSLAMAVDVTFATGPGTADPNTFALKSGPALGWSPVLHPALFQRVRAAAERLEIPYSKEIMTGLTHTDADDLQVAAEGIPTMLVSIPLRYMHTPVEVVALKDIERTGRLLAEFICQLDPNALETITWDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y2V4</accession>
    <name>A0A0P6Y2V4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BFN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_04640</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79243.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061893.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04640"/>
    <dbReference type="EnsemblBacteria" id="KPL79243">
        <property type="protein sequence ID" value="KPL79243"/>
        <property type="gene ID" value="ADN00_04640"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.690.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036104">
        <property type="entry name" value="BFN_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003729">
        <property type="entry name" value="Bi_nuclease_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02577">
        <property type="entry name" value="DUF151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103256">
        <property type="entry name" value="SSF103256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51658">
        <property type="entry name" value="BFN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BFN" evidence="2">
        <location>
            <begin position="1"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="132"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79243.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="195" mass="21779" checksum="6268C5454951C0CE" modified="2016-01-20" version="1">MIEVVIDSLRVSLTNQQRIVVLREVGRERYLPIWIGPYEAEAITIALQEIEVARPQTHDLLKNFLTSLNARLVRVEVSSLRDDVFYGNLVIETNGQIINIDSRPSDALALAVRAHVSILVSREVMDKAGVIPEENLQEPAEEQPKLPESKAPKEPASGSSEDRLSVFEDFLSNLELDDSSESGEDDEPDDDQDKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y4H6</accession>
    <name>A0A0P6Y4H6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_11090</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76510.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063079.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76510">
        <property type="protein sequence ID" value="KPL76510"/>
        <property type="gene ID" value="ADN00_11090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="21"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="293"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="54"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="295"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL76510.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="315" mass="35243" checksum="F349F4FBC3BA1EEA" modified="2016-01-20" version="1">MDETPERKPSFGATAGSVFMAFVRVVVVLLAMLILLLAAYFGVVYLYQQVIEPIQNSELRMDEMENRLQTQRQQIDERLSQFNDRLTALESQSDLHAEDMDQLRVDLEALQAAVTDQALEVRRLNQIESAVSYLATQVMEQRLERFTATPTPTPYGWKGAGEQVNLEALRSDVEVLKALLLIDRARSDLLQDQPEEAENHIRAAQSLLAALAEREPADARLRVIPGVTRRLDLALEDVATSPILSAEDLLTAWRVLEDEFIITKEIGKEIEDETGVGPEAAPDWGPTYTPIPTFTTTPTLPPMVTPTAYMTPTPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y4N3</accession>
    <name>A0A0P6Y4N3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_11400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76556.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063140.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76556">
        <property type="protein sequence ID" value="KPL76556"/>
        <property type="gene ID" value="ADN00_11400"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76556.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="98" mass="10540" checksum="D91CEC3C43038888" modified="2016-01-20" version="1">MAKIQEVRNIEGKSANDCYNAGLKAYPAAGFTVWKERSLAWLLMAKKKDKGVDVDSNLSARPTSPAQVTLGLSSDAHSEEELSAMAEQIFAALQQALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y6D9</accession>
    <name>A0A0P6Y6D9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ZnF_CDGSH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_00130</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL80998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060929.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00130"/>
    <dbReference type="EnsemblBacteria" id="KPL80998">
        <property type="protein sequence ID" value="KPL80998"/>
        <property type="gene ID" value="ADN00_00130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043231">
        <property type="term" value="C:intracellular membrane-bounded organelle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.5.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018967">
        <property type="entry name" value="FeS-contain_CDGSH-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042216">
        <property type="entry name" value="MitoNEET_CISD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09360">
        <property type="entry name" value="zf-CDGSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00704">
        <property type="entry name" value="ZnF_CDGSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ZnF_CDGSH" evidence="3">
        <location>
            <begin position="14"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL80998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="67" mass="7560" checksum="CDC2F9F8E3558B46" modified="2016-01-20" version="1">MAEHSTEEKNGYLKTWVTLHPGEKVSLCRCFKSKKFPLCDGTHKLEGTHGPVSIQVTPCEEDKKQTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y6G6</accession>
    <name>A0A0P6Y6G6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidase_A24 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_00315</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase A24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060961.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00315"/>
    <dbReference type="EnsemblBacteria" id="KPL81025">
        <property type="protein sequence ID" value="KPL81025"/>
        <property type="gene ID" value="ADN00_00315"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000045">
        <property type="entry name" value="Prepilin_IV_endopep_pep"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01478">
        <property type="entry name" value="Peptidase_A24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="92"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="114"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="193"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="231"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_A24" evidence="3">
        <location>
            <begin position="97"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL81025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="250" mass="27416" checksum="0AE4180035F2514C" modified="2016-01-20" version="1">MRFELNIILITLAGGLAGFCLNYLADVLPVYRRFTHSICQDCHEPIGWKDYILFHACPYCGRQQWLRRGLIAAITPLLLVALYIFPSGRLTFWENAVILVFFLLVAIIDIEHRLIMHPVSLAGAVIGLVLGTRMHGIFPTLIGGAAGFLMMFVLYYLGGLFAKVLGKARGEEIEEIPLGFGDVNLSGVLGLLLGWPGIAAGLFFAILAGGVFSGGYILVLKLLRRYQPFSAIPYAPFLLLGTAILLFATK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y6Z3</accession>
    <name>A0A0P6Y6Z3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Diacetylchitobiose-6-phosphate hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_09550</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
        <text evidence="6">Binds 1 NAD(+) per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the glycosyl hydrolase 4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062761.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09550"/>
    <dbReference type="EnsemblBacteria" id="KPL77351">
        <property type="protein sequence ID" value="KPL77351"/>
        <property type="gene ID" value="ADN00_09550"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4149"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001088">
        <property type="entry name" value="Glyco_hydro_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022616">
        <property type="entry name" value="Glyco_hydro_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015955">
        <property type="entry name" value="Lactate_DH/Glyco_Ohase_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32092">
        <property type="entry name" value="PTHR32092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02056">
        <property type="entry name" value="Glyco_hydro_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11975">
        <property type="entry name" value="Glyco_hydro_4C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00732">
        <property type="entry name" value="GLHYDRLASE4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56327">
        <property type="entry name" value="SSF56327"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3 6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0464">Manganese</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_4C" evidence="7">
        <location>
            <begin position="193"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF11975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL77351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="426" mass="47654" checksum="E0CB7E7BA06796F1" modified="2016-01-20" version="1">MKELKIGVIGSGSTYAPELIDGFIKRREELNVKQVVMMDVDSERLEITGNLARRMVKRAGMDTEIILTTNRREALDGASFVVTQVRVGLMEGRARDEKIPLEFGILGQETTGPGGFAMALRTIPVMLETAREMEELSPEGWMINFTNPSGLITEALSRYSKMQMIGLCNVPITYLMRFAKLYNVSVEHIYMDYFGLNHLTWMRKVYLDGKDITAEVTERILEGDAQDLLGFPFNKSMVRSLGMLPGGYLQYFYHRDRILEKQLTSGNRAEQVMKIDRELLELYSDPDLNEKPAILDQRGGAWYSDAACALISAIANDKKEIHIVNTRNKGALGGLPNDVVVEVPAMVNSAGPHPLVMGELPLGIRGLVQVVKTYEQLTVEAAVHGSREQALLALANHPLVPTVDIAEKLLDRILEENKAFLPQFYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y9F8</accession>
    <name>A0A0P6Y9F8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_06660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000018">
        <property type="protein sequence ID" value="KPL78403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062200.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000018.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06660"/>
    <dbReference type="EnsemblBacteria" id="KPL78403">
        <property type="protein sequence ID" value="KPL78403"/>
        <property type="gene ID" value="ADN00_06660"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050043">
        <property type="term" value="F:lactate racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043166">
        <property type="entry name" value="LarA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018657">
        <property type="entry name" value="LarA-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09861">
        <property type="entry name" value="Lar_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lar_N" evidence="1">
        <location>
            <begin position="32"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="Lar_N" evidence="1">
        <location>
            <begin position="139"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="419" mass="46351" checksum="E43B1390A9A4F573" modified="2016-01-20" version="1">MLQHQIIAPAGQTLIEDEIRSALFLHLEKQFSGQRVLVLIPDHTRSMPLPFLFRGLTEALRGVRQLDFMVALGTHAPLSEASLNQLVGISAEERRARCAHIGLLNHAWNDPSALVSIGAIEKDEMRQLAGNDWHASLPERVDIRINQAALAYDHILILGPTFPHEVAGFSGGAKYLFPGISGPDMINATHWLGALAGVLKTIGVKDTPVRAMIHAGAQKVRTPITLLAAVVENQALSGLFIGDYRSAWSAAADLSAQRHIRWCDRSYQRVLSCAQPMYDELWTGAKAMYKLEPVVAPGGELIIYAPHLDTVSRVHGKSIYEIGYHTLPYFVQQWDRFKHVPLGVLAHSTHVRGAGNMENGIEKPNIRVTLASKIPAEDCARLNLGYLDPASIHAADWQNREEEGILYVPHAGEILYRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YB64</accession>
    <name>A0A0P6YB64_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Uracil phosphoribosyltransferase</fullName>
            <ecNumber evidence="3 11">2.4.2.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">UMP pyrophosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">UPRTase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">upp</name>
        <name evidence="12" type="ORF">ADN00_04740</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the conversion of uracil and 5-phospho-alpha-D-ribose 1-diphosphate (PRPP) to UMP and diphosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>diphosphate + UMP = 5-phospho-alpha-D-ribose 1-diphosphate + uracil</text>
            <dbReference type="Rhea" id="RHEA:13017"/>
            <dbReference type="ChEBI" id="CHEBI:17568"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="EC" id="2.4.2.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="11">Binds 1 Mg(2+) ion per subunit. The magnesium is bound as Mg-PRPP.</text>
    </comment>
    <comment type="activity regulation">
        <text evidence="11">Allosterically activated by GTP.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 11">Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uracil: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the UPRTase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.9" evidence="3 11"/>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061807.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04740"/>
    <dbReference type="EnsemblBacteria" id="KPL79161">
        <property type="protein sequence ID" value="KPL79161"/>
        <property type="gene ID" value="ADN00_04740"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.312"/>
    <dbReference type="UniPathway" id="UPA00574">
        <property type="reaction ID" value="UER00636"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004845">
        <property type="term" value="F:uracil phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044206">
        <property type="term" value="P:UMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006223">
        <property type="term" value="P:uracil salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01218_B">
        <property type="entry name" value="Upp_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034332">
        <property type="entry name" value="Upp_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005765">
        <property type="entry name" value="Ura_phspho_trans"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01091">
        <property type="entry name" value="upp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 11" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="5 11 12" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 11" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="8 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 11 12" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="5-phospho-alpha-D-ribose 1-diphosphate binding" evidence="11">
        <location>
            <begin position="130"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Uracil binding" evidence="11">
        <location>
            <begin position="198"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>uracil</name>
            <dbReference type="ChEBI" id="CHEBI:17568"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00031082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01218"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KPL79161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="208" mass="22905" checksum="7CE8F00815D8CF2F" modified="2016-01-20" version="1">MSNVHVSNHPLVAHKLSLLRSVDTEPKKFREVVRELAILLTYEATQDLATRQIEVQTPLAKTSGAHLEQKIGLVPILRAGLGMVEGVWELMPSSEVWHIGLYRDERTLRPVEYYNKLPLEPTVSVCLILDPMLATGGSAVATMDVLKRWGAKKIKFVGLIGAPEGIAEVQKHHPDVPIYLAAIDERLNENGYIVPGLGDAGDRQFGTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GL30</accession>
    <name>A0A0N8GL30_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MFS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_16730</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064195.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL71354">
        <property type="protein sequence ID" value="KPL71354"/>
        <property type="gene ID" value="ADN00_16730"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024989">
        <property type="entry name" value="MFS_assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12832">
        <property type="entry name" value="MFS_1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="45"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="77"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="140"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="204"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="280"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="313"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="338"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="369"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="214"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL71354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="406" mass="44156" checksum="E9489EF6C4A413E1" modified="2016-01-20" version="1">MNQNTLPDKKTTWLLRLYYFAWVGAPGFIYPFLNIFFTRQGLNGQQIGLVTAASSLALLIASPFWTRWSESSRHPRRVLQAALILSGLGWIVLGRQDLFGWIFIISALRTIPAAGIWPISDDLALRLQGSSRAGYGQIRLWGSVGWAVFVLVSGWLIERSGLSIGFLSTGAAYCASALILFFLPGLESRPRQTRQETQAASQPSVLQSLWASPALLGLGGMLILTGIGNSGVLQFETVYMDDLGAREALIGVAGMFSAAVEVPGMLLADHFIRKHGHDRILLLSLILHVVMRVMVFVWPSIPVILFSRLFNGIAFSLYMVAIVVTITNHALTSQRGTMLAIFNVTLPGLVSILASPLSGAIYDAMGGRVLYLLAAIGYLVGWLGLRFTQHLPPRGMPGLPPSPAPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMB2</accession>
    <name>A0A0N8GMB2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Deoxyribodipyrimidine photolyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_13265</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the DNA photolyase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063503.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000031.1"/>
    </dbReference>
    <dbReference type="SMR" id="A0A0N8GMB2"/>
    <dbReference type="STRING" id="1134406.ADN00_13265"/>
    <dbReference type="EnsemblBacteria" id="KPL74810">
        <property type="protein sequence ID" value="KPL74810"/>
        <property type="gene ID" value="ADN00_13265"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1135"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901363">
        <property type="term" value="F:heterocyclic compound binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097159">
        <property type="term" value="F:organic cyclic compound binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051716">
        <property type="term" value="P:cellular response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006950">
        <property type="term" value="P:response to stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036134">
        <property type="entry name" value="Crypto/Photolyase_FAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036155">
        <property type="entry name" value="Crypto/Photolyase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005101">
        <property type="entry name" value="Cryptochr/Photolyase_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002081">
        <property type="entry name" value="Cryptochrome/DNA_photolyase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018394">
        <property type="entry name" value="DNA_photolyase_1_CS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006050">
        <property type="entry name" value="DNA_photolyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11455">
        <property type="entry name" value="PTHR11455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00875">
        <property type="entry name" value="DNA_photolyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03441">
        <property type="entry name" value="FAD_binding_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00147">
        <property type="entry name" value="DNAPHOTLYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48173">
        <property type="entry name" value="SSF48173"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52425">
        <property type="entry name" value="SSF52425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00394">
        <property type="entry name" value="DNA_PHOTOLYASES_1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00691">
        <property type="entry name" value="DNA_PHOTOLYASES_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51645">
        <property type="entry name" value="PHR_CRY_ALPHA_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0157">Chromophore</keyword>
    <keyword evidence="3 5" id="KW-0274">FAD</keyword>
    <keyword evidence="2 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Photolyase/cryptochrome alpha/beta" evidence="6">
        <location>
            <begin position="2"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL74810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="475" mass="53008" checksum="DC7954B1C25366C7" modified="2016-01-20" version="1">MKTAIWWVRRDLRVEDNPALKAALEVSAEVVPLFIADEGSMRLDAPKRIAFLWNGLRALDGELRKRGSRLIVRSGRPEEVLPAVLAESGAQAVFAEEDYSPYARARDLKVGDTLPLRLSVGLTAQHPVAVVKNDGAPYTVFTPFSKAWKALPQSSPAGLLANTRIHTPQGLFSEPIAAGAEVPGFPAGEEEARRRLEQFLAQKVRDYHDGRNQLDEEGTSRLSPYFRFGMLSARLAAAKMSESARKAASKGAETWLNELIWREFYQAILYHFPGVLKQAFNPALREIAWRDAPADLAAWKAGLTGYPVVDASMRQLAATGWMHNRGRMIAASFLVKDLLINWQEGETWFMHSLIDGDPASNNGGWQWTAGVGTDAAPYFRVFNPVLQGKKFDPRGDFVRAWVPELGRVPEKYIHEPWLMNLQEQSAAGCRVGRDYPAPLVDHSAARERTLEAFRASRLRWEQRQAGEQPETDLPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GN43</accession>
    <name>A0A0N8GN43_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10910</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77058">
        <property type="protein sequence ID" value="KPL77058"/>
        <property type="gene ID" value="ADN00_10910"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="18"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="112" mass="13083" checksum="D0A91BC6495CA0B3" modified="2016-01-20" version="1">MPALLAHRLHHLLTRKPAPRPSPEPPPSRLPKRRPIPPPIRLPTRLPTRPPTRPPTPLRRRIPSHQRPPIPPPIRLPPLPPLRRCHWRAKRHHPSTHPLRTCPVRSLIVNWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GN73</accession>
    <name>A0A0N8GN73_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062698.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09190"/>
    <dbReference type="EnsemblBacteria" id="KPL77298">
        <property type="protein sequence ID" value="KPL77298"/>
        <property type="gene ID" value="ADN00_09190"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4071"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010620">
        <property type="entry name" value="SBBP_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06739">
        <property type="entry name" value="SBBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006025815" evidence="1">
        <location>
            <begin position="31"/>
            <end position="914"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="914" mass="98987" checksum="FC22A05819589C16" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNR0</accession>
    <name>A0A0N8GNR0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">O-acetylhomoserine aminocarboxypropyltransferase</fullName>
            <ecNumber evidence="6">2.5.1.49</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_06085</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.49" evidence="6"/>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062077.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06085"/>
    <dbReference type="EnsemblBacteria" id="KPL78794">
        <property type="protein sequence ID" value="KPL78794"/>
        <property type="gene ID" value="ADN00_06085"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1696"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003961">
        <property type="term" value="F:O-acetylhomoserine aminocarboxypropyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00614">
        <property type="entry name" value="CGS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006235">
        <property type="entry name" value="OAc-hSer/O-AcSer_sulfhydrylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01326">
        <property type="entry name" value="OAH_OAS_sulfhy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="3">
        <location>
            <position position="213"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL78794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="433" mass="46772" checksum="C10266D9E35406D4" modified="2016-01-20" version="1">MLTNQQPRPFGFTTRQLHAGQQPDPATNSLAVPIYQTTSYVFNSTEHAANLFSLKESGNIYTRIMNPTNDVLEQRIADLEGGAGALAVSSGHAAQAHAIFTLAGAGDHIVSSSTLYGGTHTQFAHSFKRLGIEVTFVNPRDPESFRRAIRDNTKLIYGETLGNPQINVFPFEEVASIACQSGIPLMIDNTFATPYLARPFEYGANIVVHSATKFIGGHGTSLGGLIVDGGNFEWKGNPRFPNFNTPDESYHGLVFADLAESGTPPYITKARVQVLRDFGSSLAPFNAFLFLQGLETLSLRMERHVSNAQKAAEFLEAHPKVAWVAYPGLKTSPDYAAAQKYLPKGPGAILGFGIKGGAPAGMKFIESLKLFSHLANIGDAKSLAIHPATTTHSQLTEEQQISAGVSPDFIRLSIGLEDIEDILWDLDQALQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNR1</accession>
    <name>A0A0N8GNR1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_06140</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062086.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78802">
        <property type="protein sequence ID" value="KPL78802"/>
        <property type="gene ID" value="ADN00_06140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="85" mass="9377" checksum="21B850345BAF366A" modified="2016-01-20" version="1">MMQQCAFEIKIMSPQIAKHLLDPHFAFLISQGHPAIWQVGGQTPRLLFAGLPVGQQMDRTNIRLGQTPLSQLNALTALLNEAAEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNT2</accession>
    <name>A0A0N8GNT2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Adenosylhomocysteinase</fullName>
            <ecNumber evidence="4">3.3.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">S-adenosyl-L-homocysteine hydrolase</fullName>
            <shortName evidence="4">AdoHcyase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ahcY</name>
        <name evidence="9" type="ORF">ADN00_03495</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 6">
            <text>H2O + S-adenosyl-L-homocysteine = adenosine + L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:21708"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16335"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
            <dbReference type="EC" id="3.3.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4 6">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
        <text evidence="4 6">Binds 1 NAD(+) per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 6">Amino-acid biosynthesis; L-homocysteine biosynthesis; L-homocysteine from S-adenosyl-L-homocysteine: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 7">Belongs to the adenosylhomocysteinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.3.1.1" evidence="4"/>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061578.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03495"/>
    <dbReference type="EnsemblBacteria" id="KPL78970">
        <property type="protein sequence ID" value="KPL78970"/>
        <property type="gene ID" value="ADN00_03495"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.50"/>
    <dbReference type="UniPathway" id="UPA00314">
        <property type="reaction ID" value="UER00076"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004013">
        <property type="term" value="F:adenosylhomocysteinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00401">
        <property type="entry name" value="SAHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1480">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00563">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042172">
        <property type="entry name" value="Adenosylhomocyst_ase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000043">
        <property type="entry name" value="Adenosylhomocysteinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015878">
        <property type="entry name" value="Ado_hCys_hydrolase_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020082">
        <property type="entry name" value="S-Ado-L-homoCys_hydrolase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23420">
        <property type="entry name" value="PTHR23420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05221">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00670">
        <property type="entry name" value="AdoHcyase_NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001109">
        <property type="entry name" value="Ad_hcy_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00996">
        <property type="entry name" value="AdoHcyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00997">
        <property type="entry name" value="AdoHcyase_NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00936">
        <property type="entry name" value="ahcY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00738">
        <property type="entry name" value="ADOHCYASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00739">
        <property type="entry name" value="ADOHCYASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 4 6" id="KW-0520">NAD</keyword>
    <keyword evidence="2 4 6" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AdoHcyase_NAD" evidence="8">
        <location>
            <begin position="186"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="152"/>
            <end position="154"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 5">
        <location>
            <position position="185"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="215"/>
            <end position="220"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="238"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="294"/>
            <end position="296"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="341"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001109-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL78970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="419" mass="46493" checksum="A69FEC9110B828B9" modified="2016-01-20" version="1">MSNNDVKDLNLAEGGRRRIEWAEREMPVLRLIRERFAKERPLEGVRVSACLHVTTETANLMRTLQAGGADVVLTASNPLSTQDDVAASLVVHNEIPVYAIKGEDNVTYYKHLSAALDHKPMITMDDGADLVTVMHKERRELIPNVIGSMEETTTGVIRMRAMAKDGMLSFPVVAVNDAMTKHFFDNRYGTGQSTIDGIIRATNILLAGKNFVVAGYGWCGRGLAMRARGMGANVIVTEVDPMPALEAVMDGFRVMPMEEAAQIGDIFCTLTGDLNVIDRKHFEVMKDGAIVANSGHFNVEINIPALEEMSVAKRLVRPFVDQYELKDGRQIHILGEGRLINLASAEGHPASVMDMSFANQALATEYIFKHGRELEKKVYSVPEEIDREIARLKLDAMKVKIDTLTPEQVHYLNSWQEGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNY3</accession>
    <name>A0A0N8GNY3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_02780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000013">
        <property type="protein sequence ID" value="KPL79378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79378">
        <property type="protein sequence ID" value="KPL79378"/>
        <property type="gene ID" value="ADN00_02780"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="61" mass="6684" checksum="6FC98C39DC91AD0E" modified="2016-01-20" version="1">MELIVAGGRLAVWVAASVVFVLFQFDSRSNWQQAGGTQGYDESVGDSLKARLQVLQRGTRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GPD0</accession>
    <name>A0A0N8GPD0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ACT_7 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01545</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80554">
        <property type="protein sequence ID" value="KPL80554"/>
        <property type="gene ID" value="ADN00_01545"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1066"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004072">
        <property type="term" value="F:aspartate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027795">
        <property type="entry name" value="CASTOR_ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016540">
        <property type="entry name" value="UCP008459"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13840">
        <property type="entry name" value="ACT_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF008459">
        <property type="entry name" value="UCP008459"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACT_7" evidence="1">
        <location>
            <begin position="60"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="130" mass="13942" checksum="185DEEDC14F11A59" modified="2016-01-20" version="1">MTMPLPRLQIMPQRLAVARLDPAADIPAWLPREGFLSITRTSDELSIVVDEQALPGRVTAETGWRILKVLGPLDFSLVGVLASLANPLAAAGVSIFAISTYDTDYLLVREAQFALALAALAEAGFDLLPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GPI8</accession>
    <name>A0A0N8GPI8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">F420-dependent oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_00260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060952.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00260"/>
    <dbReference type="EnsemblBacteria" id="KPL81018">
        <property type="protein sequence ID" value="KPL81018"/>
        <property type="gene ID" value="ADN00_00260"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3446"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011251">
        <property type="entry name" value="Luciferase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036661">
        <property type="entry name" value="Luciferase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00296">
        <property type="entry name" value="Bac_luciferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51679">
        <property type="entry name" value="SSF51679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bac_luciferase" evidence="1">
        <location>
            <begin position="13"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL81018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="332" mass="37094" checksum="A4B7E85A62D9EAE2" modified="2016-01-20" version="1">MAERVALYLQDAHDLRDGLEYVKYAEKRGFEAVWQAESRLVRDAIVPMAAYAAVTEKIKIGSGVINNWTRNIGLLAATYLTLDDLAPDRIICGIGAWWDPLAANVGIDRKKPLRAMYETIVVMRKLLNLERVSYDGEFVHVKDIELDVVHGRREPRNVPLMIGATGDKMMELSGEIADGVVLNYCVEPSYNEKALELLSIGAARSGRKLEDIDRPQLIVCSVDHDHDKAYDATRMLLTQYLAQQPHIAKASNVSMDVVAEIQSILGWPATHEQIEKAKHFVSDELIERITASGTPEEARTKVNEYRKNGCTCPILYSAGGDIRLLIDTFAQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WJY6</accession>
    <name>A0A0P6WJY6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CHAD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_18015</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL69969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064434.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18015"/>
    <dbReference type="EnsemblBacteria" id="KPL69969">
        <property type="protein sequence ID" value="KPL69969"/>
        <property type="gene ID" value="ADN00_18015"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.40.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007899">
        <property type="entry name" value="CHAD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038186">
        <property type="entry name" value="CHAD_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05235">
        <property type="entry name" value="CHAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00880">
        <property type="entry name" value="CHAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51708">
        <property type="entry name" value="CHAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CHAD" evidence="1">
        <location>
            <begin position="4"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51708"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL69969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="336" mass="39103" checksum="88381FB7C6920BE9" modified="2016-01-20" version="1">MKKKKKMDECTCSFGAEIIEKHRQAVAAEIDGVIQSDDIEYIHRMRVATRRLRSAIPLFQSCFSKNQAADWLKQSRAVTRALGEARDLDVQIEKLDQAIAAVKTVQFRPGMRRLRLRLTQKRLSIHNHVIEAMRQLQESRLLPRIETTLAPYLVTPTGQPPSLPLYQLAAQAITQRLDIFLACEASIFDPKNIHELHQMRIEAKRLRYTLEIFATLYPGECKSELKAIKSVQELLGDIHDCDVWTEFLPEFITQETYRALEYHGHTRAMNILRPGLQHFLQFQQQTRAELYQRFLVEWQSWQQENVWPQLRQIVSAPLDVYPNESATDAPREQPCE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WK37</accession>
    <name>A0A0P6WK37_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">TGc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_18395</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18395"/>
    <dbReference type="EnsemblBacteria" id="KPL70033">
        <property type="protein sequence ID" value="KPL70033"/>
        <property type="gene ID" value="ADN00_18395"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002931">
        <property type="entry name" value="Transglutaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01841">
        <property type="entry name" value="Transglut_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00460">
        <property type="entry name" value="TGc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="145"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="174"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="211"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="626"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="domain" description="TGc" evidence="3">
        <location>
            <begin position="495"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="575"/>
            <end position="605"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL70033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="775" mass="86057" checksum="C4CE82FB0E61423E" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WPQ8</accession>
    <name>A0A0P6WPQ8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">2-hydroxyacid dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_16380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064117.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16380"/>
    <dbReference type="EnsemblBacteria" id="KPL72054">
        <property type="protein sequence ID" value="KPL72054"/>
        <property type="gene ID" value="ADN00_16380"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.645.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001135">
        <property type="entry name" value="NADH_Q_OxRdtase_suD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001501">
        <property type="entry name" value="Ni-dep_hyd_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029014">
        <property type="entry name" value="NiFe-Hase_large"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00346">
        <property type="entry name" value="Complex1_49kDa"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00374">
        <property type="entry name" value="NiFeSe_Hases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56762">
        <property type="entry name" value="SSF56762"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Complex1_49kDa" evidence="1">
        <location>
            <begin position="116"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="Complex1_49kDa" evidence="1">
        <location>
            <begin position="286"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="359" mass="39654" checksum="644F256891E5F826" modified="2016-01-20" version="1">MPYKIPIGPLHPAYEEPYKLTLTCKGEVVQDVQVEVGFILRSIELLAQRRNYIRDLVLVEHVCGICSNVHASTFAMAVEKIAGIEIPARARYIRTIMSELERLHSHLLWAGIGSEDIGYHSMFMEIYMLRERVMDILETISGNRVNYGMITLGGVARDIQDPQAILNVVKEVKVALEQVVIPIFTHDATIIARTKGIGILTRQDALAYGAVGPLARASGIAEDIRESVPYAAYTELGFKKVVQESCDVQARVIVRALEMIESVRLIEEALKNLPSGAYRLDDIPLTIPAGEAAVRSEAPRGEVFYYVASDGSDTPARVKIRTPSFVNIPSIKAMVKGQYLADIPLIQASIDPCCSCTDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WSM1</accession>
    <name>A0A0P6WSM1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_15910</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL71987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064028.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15910"/>
    <dbReference type="EnsemblBacteria" id="KPL71987">
        <property type="protein sequence ID" value="KPL71987"/>
        <property type="gene ID" value="ADN00_15910"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025517">
        <property type="entry name" value="DUF4405"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14358">
        <property type="entry name" value="DUF4405"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4405" evidence="2">
        <location>
            <begin position="16"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4405" evidence="2">
        <location>
            <begin position="113"/>
            <end position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL71987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="212" mass="23838" checksum="1543D50B4351F222" modified="2016-01-20" version="1">MKSLQVSEKTRKFWTVDALLGISAIVATVSGVYFLFFPLGYRGGRNPLYSTIVLFDRTTWDLLHTWFGLLMVVIAAIHLILHWDWVAKMTQKMLILIRGKACGLTAYGQFNMWLDFVLAFSFMLTAVSGVALLAITGIPVPEIASGILLSQTAWDMIHTWAGIVMVITTIVHLAIHWRWVVNVSRKIFFRSGSMRQAEAQTCSEKNSREAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WT00</accession>
    <name>A0A0P6WT00_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">2-amino-3-ketobutyrate CoA ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_15315</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72197.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063910.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15315"/>
    <dbReference type="EnsemblBacteria" id="KPL72197">
        <property type="protein sequence ID" value="KPL72197"/>
        <property type="gene ID" value="ADN00_15315"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.765"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001917">
        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00599">
        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="3">
        <location>
            <begin position="47"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL72197.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="392" mass="42637" checksum="E12D0E7B4FAF3C41" modified="2016-01-20" version="1">MDIFEKCFSYTTVKEAIKEGFYPFFIPLSENEGTEVEYRGHRLIMCGSNNYLGLTTHPKVREAAIEAIRRFGTSCTGSRFLNGTLEMHEQLEAELAEWVGKPAALTFSTGMQVNLGTVSALVGRDDIVILDKDDHASIVDGARLGYGKIQRFRHNDMEHLECVLKGLPDNAGKLIVVDGLFSMEGDLAPLDEMTVIAKKYNARLMVDDAHGMGVNGGGHGTAWQFGVTDQVDLIMSTFSKSFASLGGFVAGDADVIDYVKHHARALIFSASMPPANTAAALAALDVMRQEPDLAARVNANAEKIRNGLKSLGFNTGRSVTPVVPVIIGDDQLTFLTWKSLFEEGVFVNPVISPAVAPGHQLLRTSYMATHTDEQLDKVLGIFEKVGKQVGLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WTG6</accession>
    <name>A0A0P6WTG6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_18795</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064577.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70093">
        <property type="protein sequence ID" value="KPL70093"/>
        <property type="gene ID" value="ADN00_18795"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132626" evidence="1">
        <location>
            <begin position="26"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="163" mass="17130" checksum="9E8C6EF9BD491307" modified="2016-01-20" version="1">MQAKTRSLILSISLVLSLFIGACGAISSAAPAGTLGAAETIEGMRMVVANEAGTFLMQKGEVFLMAWPRGTNYAMTVLSQSGASDALNGMRVNAVSLTETVKALEADGWKYITPAALPKAITEALAAYSVEMAVTALKGLPTVFIMPIFMVTPDFLQPEVVIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WTJ9</accession>
    <name>A0A0P6WTJ9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Holo-[acyl-carrier-protein] synthase</fullName>
            <shortName evidence="8">Holo-ACP synthase</shortName>
            <ecNumber evidence="8">2.7.8.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">4'-phosphopantetheinyl transferase AcpS</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">acpS</name>
        <name evidence="10" type="ORF">ADN00_14625</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>apo-[ACP] + CoA = adenosine 3',5'-bisphosphate + H(+) + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:12068"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9690"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:58343"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="EC" id="2.7.8.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the P-Pant transferase superfamily. AcpS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.7" evidence="8"/>
    <dbReference type="EMBL" id="LGCL01000035">
        <property type="protein sequence ID" value="KPL73572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063772.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000035.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14625"/>
    <dbReference type="EnsemblBacteria" id="KPL73572">
        <property type="protein sequence ID" value="KPL73572"/>
        <property type="gene ID" value="ADN00_14625"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2091"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008897">
        <property type="term" value="F:holo-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00101">
        <property type="entry name" value="AcpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008278">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002582">
        <property type="entry name" value="ACPS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004568">
        <property type="entry name" value="Ppantetheine-prot_Trfase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01648">
        <property type="entry name" value="ACPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="SSF56214"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00516">
        <property type="entry name" value="acpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00556">
        <property type="entry name" value="pantethn_trn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="4 8" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="1 8" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6 8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACPS" evidence="9">
        <location>
            <begin position="9"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="11"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL73572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="129" mass="13932" checksum="A3379446A08B5CA5" modified="2016-01-20" version="1">MKQPVLRTGVDLVEIHRLEQVNPAIRTRFLRRVYTPGELADVGESAYASLAGRFAAKEAASKALGTGIGPVRWQDFEIRRGLAGEPVLELHGKARQIADLLGLSLWSVSISHSKDNAVAVVVAMGESTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WX06</accession>
    <name>A0A0P6WX06_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4190 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_13240</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063498.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000031.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13240"/>
    <dbReference type="EnsemblBacteria" id="KPL74806">
        <property type="protein sequence ID" value="KPL74806"/>
        <property type="gene ID" value="ADN00_13240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025241">
        <property type="entry name" value="DUF4190"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13828">
        <property type="entry name" value="DUF4190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4190" evidence="2">
        <location>
            <begin position="18"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL74806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="114" mass="11747" checksum="9F6C6ED8CD07B560" modified="2016-01-20" version="1">MSQSYQAPPPVAQTSTPAIISLISGILSWVGVFGLGGILAVIFGHIAKKEIRKSGGYLTGDGMATAGLVLGYANIALSLVGLCFFVLMMTGAIAAPLVCIPFGNQFNTNFSLIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WX58</accession>
    <name>A0A0P6WX58_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_13510</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13510"/>
    <dbReference type="EnsemblBacteria" id="KPL74861">
        <property type="protein sequence ID" value="KPL74861"/>
        <property type="gene ID" value="ADN00_13510"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL74861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="292" mass="32555" checksum="F280147D6B784BFB" modified="2016-01-20" version="1">MANLNDLECVVLENDLLRILVPKALGPRILSLCFRGGENLLAVLPDVTTERPDGKQYHFFGGHRLWLAPEDPLLSYAFDDQAVEITSSEAGLLIRKEAESETGIEKSILVNLDPQQAKLTLTHRLTNRSSRPVEYAPWTITQFRTGGLAILPQSGAQTGLLPNRTLSLWPYTDITSPCLKLGNQFILLHANMQTPFKVGFPNPRGWMAYWLDGVLFVKKAAFDPQGRYPDNGSSSECYCNQSFLELETLAPLALIEPDASATHTETWELHSDIPMPNDESAIQAILQKIRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WY12</accession>
    <name>A0A0P6WY12_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ribosome-recycling factor</fullName>
            <shortName evidence="3">RRF</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Ribosome-releasing factor</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 6" type="primary">frr</name>
        <name evidence="6" type="ORF">ADN00_14650</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Responsible for the release of ribosomes from messenger RNA at the termination of protein biosynthesis. May increase the efficiency of translation by recycling ribosomes from one round of translation to another.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the RRF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000035">
        <property type="protein sequence ID" value="KPL73577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063777.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000035.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14650"/>
    <dbReference type="EnsemblBacteria" id="KPL73577">
        <property type="protein sequence ID" value="KPL73577"/>
        <property type="gene ID" value="ADN00_14650"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2096"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006415">
        <property type="term" value="P:translational termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00520">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.132.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00040">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002661">
        <property type="entry name" value="Ribosome_recyc_fac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023584">
        <property type="entry name" value="Ribosome_recyc_fac_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036191">
        <property type="entry name" value="RRF_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20982">
        <property type="entry name" value="PTHR20982"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01765">
        <property type="entry name" value="RRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55194">
        <property type="entry name" value="SSF55194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00496">
        <property type="entry name" value="frr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RRF" evidence="5">
        <location>
            <begin position="20"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="139"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL73577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="185" mass="21068" checksum="A2220DD615DA4862" modified="2016-01-20" version="1">MIKETLKDAETRMQGAIDALEEDLATIRTGRATPALIEKMPVDYYGAPTPLQQLATISVPEARALMIRPFDPTTIKHIERAILASDLGLTPNNDGKVIRLNLPPLTEERRRDLAKVVHNRTEEARVAARNVRRDIVKDLRDFEKEKMISEDDMKRAEEELQKLTDKMIALIDQAGERKQKEVMEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WYS7</accession>
    <name>A0A0P6WYS7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AraC_E_bind domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_14445</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000034">
        <property type="protein sequence ID" value="KPL73760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063733.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000034.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL73760">
        <property type="protein sequence ID" value="KPL73760"/>
        <property type="gene ID" value="ADN00_14445"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010499">
        <property type="entry name" value="AraC_E-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029441">
        <property type="entry name" value="Cass2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011256">
        <property type="entry name" value="Reg_factor_effector_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14526">
        <property type="entry name" value="Cass2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00871">
        <property type="entry name" value="AraC_E_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55136">
        <property type="entry name" value="SSF55136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AraC_E_bind" evidence="1">
        <location>
            <begin position="3"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL73760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="172" mass="19536" checksum="30B1BEDC90384E1B" modified="2016-01-20" version="1">MLKPTRLIERPEMWLAGFAFYGDPFQLRGGWDEENEIGRLWQRFGRFCAEQPGSLPSALEPGTGYEVHIQHLETGERGEYEVFVGFQVEPEAGIPIQFSLKRLPPAQYAVFTLRGAEISADWDAQISAWLAEAGWVSDFGFNLQCYDARFKGMQDLADSEVDVWVPVRRSGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZ28</accession>
    <name>A0A0P6WZ28_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_15985</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL71998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064041.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL71998">
        <property type="protein sequence ID" value="KPL71998"/>
        <property type="gene ID" value="ADN00_15985"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="170"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="271"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="303"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="336"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="367"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="432"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="463"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL71998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="626" mass="70651" checksum="62C103F8CE5188BF" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZE5</accession>
    <name>A0A0P6WZE5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ATP-dependent zinc metalloprotease FtsH</fullName>
            <ecNumber evidence="6">3.4.24.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ftsH</name>
        <name evidence="9" type="ORF">ADN00_15220</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
            <orientation evidence="6">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">In the C-terminal section; belongs to the peptidase M41 family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">In the central section; belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.24.-" evidence="6"/>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063892.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15220"/>
    <dbReference type="EnsemblBacteria" id="KPL72181">
        <property type="protein sequence ID" value="KPL72181"/>
        <property type="gene ID" value="ADN00_15220"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.746"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030163">
        <property type="term" value="P:protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01458">
        <property type="entry name" value="FtsH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041569">
        <property type="entry name" value="AAA_lid_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005936">
        <property type="entry name" value="FtsH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000642">
        <property type="entry name" value="Peptidase_M41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037219">
        <property type="entry name" value="Peptidase_M41-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17862">
        <property type="entry name" value="AAA_lid_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01434">
        <property type="entry name" value="Peptidase_M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140990">
        <property type="entry name" value="SSF140990"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01241">
        <property type="entry name" value="FtsH_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="9" id="KW-0132">Cell division</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="109"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="domain" description="AAA" evidence="8">
        <location>
            <begin position="196"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="427"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="204"/>
            <end position="211"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="426"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="430"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="502"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL72181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="620" mass="68151" checksum="53F814C8838FE9C3" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZW9</accession>
    <name>A0A0P6WZW9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_14025</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063654.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000033.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74117">
        <property type="protein sequence ID" value="KPL74117"/>
        <property type="gene ID" value="ADN00_14025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="45"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="225"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="261"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="288"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="314"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="350"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="378"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="13"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL74117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="425" mass="45828" checksum="A51E6AECB164F783" modified="2016-01-20" version="1">MRPTEDTKRWVIPFFTIWTGQSISLIGSRIAQFALVWWLTETTGSATVLATASMVALIPEIVLAPFSGALTDRWKRRRVMIFADTLMALAALWLAYLFWSGSMQIWHVYVVMTVRAVGNSFHWPAMEASTGMMVPKSQLSRVQGINQTMRGVLNIVAPPLGALFLDLLPLHQVMMIDVGTAALAVTPLLFIAVPQPERAAHEANTSVWADMVSGLRYLVSWRGMMVFIGAIMLLKIALSPAFSLLPLLVRQHFQGGAAELSLLQAINGIGVVAGGLVLSLWGGFRRRVHTMLAGIALLGVSILALGFIPPHLYWLALVSIFVLGFMVPMVDGPFMAISQACVAPEMQGRVFGVMGSLLSITSPISLAMAGPISDRLGLQIWYLAAGGICVLIGLIGSRVPAIMQIEGESEISPAATAAAVNPERV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZX8</accession>
    <name>A0A0P6WZX8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Xylulose kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_12630</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL75492">
        <property type="protein sequence ID" value="KPL75492"/>
        <property type="gene ID" value="ADN00_12630"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1218"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000577">
        <property type="entry name" value="Carb_kinase_FGGY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="Carb_kinase_FGGY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018484">
        <property type="entry name" value="Carb_kinase_FGGY_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02782">
        <property type="entry name" value="FGGY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00370">
        <property type="entry name" value="FGGY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000538">
        <property type="entry name" value="GlpK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FGGY_N" evidence="1">
        <location>
            <begin position="11"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="FGGY_C" evidence="2">
        <location>
            <begin position="281"/>
            <end position="475"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL75492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="528" mass="57940" checksum="69F10825B0FB3FB6" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X134</accession>
    <name>A0A0P6X134_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein-export membrane protein SecG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ADN00_11885</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in protein export. Participates in an early event of protein translocation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the SecG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063234.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11885"/>
    <dbReference type="EnsemblBacteria" id="KPL76049">
        <property type="protein sequence ID" value="KPL76049"/>
        <property type="gene ID" value="ADN00_11885"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015450">
        <property type="term" value="F:protein-transporting ATPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004692">
        <property type="entry name" value="SecG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03840">
        <property type="entry name" value="SecG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00810">
        <property type="entry name" value="secG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9" id="KW-0811">Translocation</keyword>
    <keyword evidence="4 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="53"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU365087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL76049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="75" mass="7874" checksum="DAD5AB32707C86B8" modified="2016-01-20" version="1">MNLSDFFDIALIITSIALIGSVILQNKGVGLGGLTGADSSSVFTARRGIEKTLFWITIGLSGLFFILTILAVVVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X2D9</accession>
    <name>A0A0P6X2D9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Leucine/isoleucine/valine transporter ATP-binding subunit</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">livG</name>
        <name evidence="5" type="ORF">ADN00_14370</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000034">
        <property type="protein sequence ID" value="KPL73750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063721.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000034.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14370"/>
    <dbReference type="EnsemblBacteria" id="KPL73750">
        <property type="protein sequence ID" value="KPL73750"/>
        <property type="gene ID" value="ADN00_14370"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1393"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032823">
        <property type="entry name" value="BCA_ABC_TP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12399">
        <property type="entry name" value="BCA_ABC_TP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="6"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL73750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="256" mass="28334" checksum="8F98454FDAD28DC7" modified="2016-01-20" version="1">MTETILKITDLQKNFGGVVATRDFSLDIEKNKIVGLIGPNGAGKTTIFNIITGIYQPSGGSVEFMGNNIVGKKPYQIALAGIARTFQNIRLFTNLSVLDNVIIASHQDCNYSIFSEMTHLGSFKKTEKAVREHAMQLLEMVGLQDITNRIAGGLPYGHQRRLEIARALAIHPKLLLLDEPAAGMNADESEDLCNFIFDLHRKFDLTIFLIEHHMDVVVKLCDSITVLNFGQTICQGTPEQVIAEPCVIEAYLGEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X2E5</accession>
    <name>A0A0P6X2E5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Methyl-accepting transducer domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_14435</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000034">
        <property type="protein sequence ID" value="KPL73759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063731.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000034.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14435"/>
    <dbReference type="EnsemblBacteria" id="KPL73759">
        <property type="protein sequence ID" value="KPL73759"/>
        <property type="gene ID" value="ADN00_14435"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0807">Transducer</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="31"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="3">
        <location>
            <begin position="219"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL73759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="736" mass="79942" checksum="0BA56E86157BC060" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X2Q6</accession>
    <name>A0A0P6X2Q6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cas_APE2256 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000028">
        <property type="protein sequence ID" value="KPL75305.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063455.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000028.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL75305">
        <property type="protein sequence ID" value="KPL75305"/>
        <property type="gene ID" value="ADN00_13010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013442">
        <property type="entry name" value="SSO1393-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09651">
        <property type="entry name" value="Cas_APE2256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cas_APE2256" evidence="1">
        <location>
            <begin position="173"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL75305.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="350" mass="39887" checksum="4EDF849C851E6BDE" modified="2016-01-20" version="1">MARRFIFTTGTSLLGNFIKKYYDPPNIAEGVFDNRFPREIDILHTPSVRWDGFRAFHYPEMQMDKGIAWNMINTWSTIQARESYQTAEVDSLSFLPVDPENDEVILLASNTPPGLFCALVNANLMTQHGTPVSIWEDVLQEHSQFPIVDWDPENEISWRPIANPLANPAIVLTINQLDPNKKTTFENQALGNLVRSVSLLILHAMDHNMEPHVIFTGGYKATIPFLTLVCSWMGNITMWSLYEDSKEILRIPVPKANLDSRIYRMIAGKLALEMKQDDPYYALFSRWTSKANYTQLSSMDPADQPFFVNHPQPNQPVQLSPMGKAFAEVLRAQLGSAYFKEELKSILSNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X2U9</accession>
    <name>A0A0P6X2U9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CRISPR_Cas6 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_14235</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000034">
        <property type="protein sequence ID" value="KPL73726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063697.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000034.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14235"/>
    <dbReference type="EnsemblBacteria" id="KPL73726">
        <property type="protein sequence ID" value="KPL73726"/>
        <property type="gene ID" value="ADN00_14235"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019267">
        <property type="entry name" value="CRISPR-assoc_Cas6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045747">
        <property type="entry name" value="CRISPR-assoc_prot_Cas6_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10040">
        <property type="entry name" value="CRISPR_Cas6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRISPR_Cas6" evidence="1">
        <location>
            <begin position="161"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL73726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="287" mass="31033" checksum="E82C8448CF32AE77" modified="2016-01-20" version="1">MNETPTPELLSLVLTLRPLAAPQPDRPLPNWWGRAAHTLLLATVSAADPALAARLHDDEGLKPFTASTLMGRFLRGQPLPDQTYRLRFTALTAELSAALLAAVHSGPLAPGARVELDYLPFEILAAASAEDETGWPGATTYQDLGARRLLAGSAPERRITLSFTSPVAFKSKDRTMPLPLPDLVFGSLLQKWNAFAPLSLPAELRRYASECLAISRFHLRSHGVGAKDNGLRVGAAGEITYATLNYDRYWMSLIHALGEFARFAGVGAAVSQGMGQARRLPTPGRED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X423</accession>
    <name>A0A0P6X423_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Tungsten ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_12165</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063377.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12165"/>
    <dbReference type="EnsemblBacteria" id="KPL76174">
        <property type="protein sequence ID" value="KPL76174"/>
        <property type="gene ID" value="ADN00_12165"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3909"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024370">
        <property type="entry name" value="PBP_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12849">
        <property type="entry name" value="PBP_like_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132822" evidence="1">
        <location>
            <begin position="22"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="PBP_domain" evidence="2">
        <location>
            <begin position="30"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL76174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="288" mass="30950" checksum="AD192CEA0F438DCC" modified="2016-01-20" version="1">MKKFISVLLILMMVYAAGCNAVVPTEAAAPATENSELILATTTSTRDSGLLDTLLPMFQEQTGYQVKMVAVGTGQALQMGQEGNADVLLVHAPASEKEFMQNGFGQRRDLVMHNDFVMVGPVDDPAGIKGLATAAEAMAKIASSKAVFVSRGDDSGTHKMELNLWNKAGVEPAGQWYLETGQGMGETLRVASEKIGYTITDRATYLAQRDTLELEILVEGDASLLNIYSVIVVNTEKWPEINEDGANAFADFLTAEDTQKAIAEFGVKDFGQPLFFPDAGKDEASLGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X482</accession>
    <name>A0A0P6X482_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_08355</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062529.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08355"/>
    <dbReference type="EnsemblBacteria" id="KPL77878">
        <property type="protein sequence ID" value="KPL77878"/>
        <property type="gene ID" value="ADN00_08355"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.673"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018746">
        <property type="entry name" value="DUF2298"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10060">
        <property type="entry name" value="DUF2298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03662">
        <property type="entry name" value="Chlor_Arch_YYY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="158"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="185"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="217"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="329"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="383"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="406"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="435"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="475"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="514"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="556"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="587"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="620"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="654"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="685"/>
            <end position="704"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="865" mass="97168" checksum="04C5B0086BD50D05" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X4Z2</accession>
    <name>A0A0P6X4Z2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_09760</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76878.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062813.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09760"/>
    <dbReference type="EnsemblBacteria" id="KPL76878">
        <property type="protein sequence ID" value="KPL76878"/>
        <property type="gene ID" value="ADN00_09760"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2409"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003339">
        <property type="entry name" value="ABC/ECF_trnsptr_transmembrane"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02361">
        <property type="entry name" value="CbiQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="44"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="122"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="248"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL76878.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="278" mass="31877" checksum="168F639B50A64642" modified="2016-01-20" version="1">MNPKMKIFSYNSADTYIHRLSGLTKLLCFLLLTFAVMYSYDIRVILAVMAFSVLLMRLSLIQFSQIRVMVIYVLIFLATNAVISFFFSPEFGVSIYGTRHEFARVFGVSLTYEQLFYQVTKFFKYAAVVPLGMIFLLTTNPSEFASSLNGIGVNYKAAYAVALTLRYFPDIQRDYHDIYLSQQARGLELSQKAKFLDRFKNSLLIVIPLIFSTLDRIEVISNAMDLRGFSKSKTRTWYTSRKLNRQDALALGVSALIFLIALGVSLFINHSRFYNPFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X534</accession>
    <name>A0A0P6X534_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA mismatch repair protein MutS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_18055</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL69976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064442.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18055"/>
    <dbReference type="EnsemblBacteria" id="KPL69976">
        <property type="protein sequence ID" value="KPL69976"/>
        <property type="gene ID" value="ADN00_18055"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2912"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS_family"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="PTHR11361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_MISMATCH_REPAIR_2" evidence="3">
        <location>
            <begin position="330"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL69976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="511" mass="58305" checksum="016B010BB817904C" modified="2016-01-20" version="1">MSFQSILFDTNESPVPEIATEMPVFFSDLNLDQVVEVITAKKKDYQLAPFFYTPLKNIKTIEYRHAVMQDLGDSVLFGNVQAFASGMVTVRGFLTRAGKAYYELQAQRWFLDAVQVYCETVLRLKEDLSQVQLGAQGLIGFRNYLNDYVNSERFKRLLRETKTLEDDLASVCYTLIIKGTTIKVRKLEPASDYSEEVIQTFEKFKQGAVKDYRVTLTDRPDMNHVEAKVLEMVAQLHPEIFTSLATFCSENLSFIDEVIGNFDREIQFYISYLEYMGTFKKIGLSFCYPEISTESKEILSRDSFDLALAHNLNRENAMVVCNDFELKGKERIIVVSGPNQGGKTTFARAFGQLHYLASLGCPVPGSAAKLFLYDQLFTHFEKEETISNQSGKLQDDLVRIHEILEQATPNSLIIMNEIFTSTTLKDAVVLSKLIFKEIIDLDMLCVCVTFIDELSRLGEKTISMVSTVTPEDSNQRTFKIIRRDADGISYAISIVEKYHLTYQHLKERIKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5C6</accession>
    <name>A0A0P6X5C6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_07165</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78244.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07165"/>
    <dbReference type="EnsemblBacteria" id="KPL78244">
        <property type="protein sequence ID" value="KPL78244"/>
        <property type="gene ID" value="ADN00_07165"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3251"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004526">
        <property type="term" value="F:ribonuclease P activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000100">
        <property type="entry name" value="RNase_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020539">
        <property type="entry name" value="RNase_P_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33992">
        <property type="entry name" value="PTHR33992"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00825">
        <property type="entry name" value="Ribonuclease_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00188">
        <property type="entry name" value="rnpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00648">
        <property type="entry name" value="RIBONUCLEASE_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL78244.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="84" mass="9203" checksum="814F603421E115E3" modified="2016-01-20" version="1">MIVDPVEQGGIKIGISASHTVGNAVNRNRVKRRLRAVMDELLPALQANTDVILLARKPIVDASFDDLRKAVSELLMRAGLLTRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5G1</accession>
    <name>A0A0P6X5G1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Magnesium transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_19150</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CorA metal ion transporter (MIT) (TC 1.A.35) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70150.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064643.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_19150"/>
    <dbReference type="EnsemblBacteria" id="KPL70150">
        <property type="protein sequence ID" value="KPL70150"/>
        <property type="gene ID" value="ADN00_19150"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3142"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046873">
        <property type="term" value="F:metal ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045861">
        <property type="entry name" value="CorA_cytoplasmic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045863">
        <property type="entry name" value="CorA_TM1_TM2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002523">
        <property type="entry name" value="MgTranspt_CorA/ZnTranspt_ZntB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01544">
        <property type="entry name" value="CorA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143865">
        <property type="entry name" value="SSF143865"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144083">
        <property type="entry name" value="SSF144083"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="253"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="283"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL70150.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="310" mass="35255" checksum="021CA76A2C99E993" modified="2016-01-20" version="1">MISILKSTPSGLEPQTEPSSGCWINVVDPTTDEIESLSKLGIPQDFITYPLDVDERSRTEREDDGTVLIVLRVPYFQGMRADIPYITIPLGIIINEDLIVTICRWKNDVLQKFLGGQVRAFSTAKHNQFVLKLLLHTASKYLSDLREINRATDILEDQLQLSMNNNQLMEILKYQKSMVYFTTALKSNELMLERLQRSQLFRMYAEDEDLLEDVITENQQAIEMTNIYNTILSSMMDAFASIISNNMNMVMKFLASVTIVLSLPTIATSFFGMNVPLPLENNAVGYLIILGATVIISLIVVAVFYKRDWF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5X9</accession>
    <name>A0A0P6X5X9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_06855</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000018">
        <property type="protein sequence ID" value="KPL78436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062238.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000018.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06855"/>
    <dbReference type="EnsemblBacteria" id="KPL78436">
        <property type="protein sequence ID" value="KPL78436"/>
        <property type="gene ID" value="ADN00_06855"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase_N" evidence="2">
        <location>
            <begin position="4"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase_C" evidence="3">
        <location>
            <begin position="259"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL78436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="387" mass="41198" checksum="CA1E2A605D769EF5" modified="2016-01-20" version="1">MTEVIIAGIGQTPVGEHWELSLRTLAARAIRAALRDAGDLQPQAVYIGNFLSSQIIHQSNLGALITTNSGLEGLEAFTLEAANASGAAAFRMGYLAVASGYVDTAVVVGVEKVSDVAPQELEAYAAQAMDYDYEIMQGLTLSAQAALLMRRYMHEFDVPREAFAAYPMLAHANAAGNPNAYFRRPMKLESYQRAGMVADPLNLFDTAPLLDGAAAVVLTRSGKLPADYPHPLVRVVGSSLVTDAISLHDRPDPLAFRAAALSVERACRQAGILPEDIDFFELSDNYSFYAPLALEAAGFAKRGEGWKLAQSGAHARGGRLPLNTMGGAQGRGNPLAASGVYQIVEAVQQLRGHAGDNQLARAHRAMTQSLGGAAGTAVTHILERWQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X6L9</accession>
    <name>A0A0P6X6L9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PTS EIIA type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05550</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78710.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061979.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05550"/>
    <dbReference type="EnsemblBacteria" id="KPL78710">
        <property type="protein sequence ID" value="KPL78710"/>
        <property type="gene ID" value="ADN00_05550"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00211">
        <property type="entry name" value="PTS_IIA_fru"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016152">
        <property type="entry name" value="PTrfase/Anion_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002178">
        <property type="entry name" value="PTS_EIIA_type-2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00359">
        <property type="entry name" value="PTS_EIIA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55804">
        <property type="entry name" value="SSF55804"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51094">
        <property type="entry name" value="PTS_EIIA_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00372">
        <property type="entry name" value="PTS_EIIA_TYPE_2_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PTS EIIA type-2" evidence="1">
        <location>
            <begin position="2"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78710.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="142" mass="15338" checksum="CD7B6495CB4E63FE" modified="2016-01-20" version="1">MAIVSKERICLQASAMDKEEAIRKAGDLLVESGCVLPPYIDGMLAREQSMSTSLGNGVAIPHGVYENRDHILKTGISVLQLPDGVDWDEDEKVYLVIGIAATSDEHVEVLSNLADVIDDENNLSELLSTTDPDVIVKYLGVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7B6</accession>
    <name>A0A0P6X7B6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PfkB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_18405</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064513.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18405"/>
    <dbReference type="EnsemblBacteria" id="KPL70035">
        <property type="protein sequence ID" value="KPL70035"/>
        <property type="gene ID" value="ADN00_18405"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2988"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00584">
        <property type="entry name" value="PFKB_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="3">
        <location>
            <begin position="193"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL70035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="341" mass="37831" checksum="06B566CBD8868B2F" modified="2016-01-20" version="1">MFDFESRSALRFVIAGRFTRDFIIDLEGQPHMDIPGGGGIYSAVGLALWEQGVGLLGRIGEDFPQHWLEKWKERGFDTSGVKILDQALDLRRFIQYAGVDTPQQDNPISHFSQRGLPFPKTLLGYQNPVHQPDSKTVSNDHTLRLTDLPMHYLDATAVHLAPLDFLSHSILLPRVQQGNASTITIEPSRGSMDATFWDDIPNLVKGITAFHTNEEKIRALFHGRSTDLWEMAEKIASYGCEFVVIKRKAAGQYLYDATRKTRWIIPAYPARVTDPTGAGDAFCGGFLAGYRSFYDPVEAALCGNISASFVIEGSGPLYALDALPGLAQARLESLRSSVRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7F8</accession>
    <name>A0A0P6X7F8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Hydrolase_4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_08460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062550.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08460"/>
    <dbReference type="EnsemblBacteria" id="KPL77893">
        <property type="protein sequence ID" value="KPL77893"/>
        <property type="gene ID" value="ADN00_08460"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.695"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydrolase_4" evidence="1">
        <location>
            <begin position="27"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="284" mass="30978" checksum="A4F23EF1C91DC372" modified="2016-01-20" version="1">MRSETGSWKTENGLQIYTRTWLPESSIRACVVLVHGLGEHSGRYAHLASYLTDKGIAVYTFDLPGHGQTQGSRGHIPSYSFVSRMLADFCAEVSRNQPKIPLILYGHSLGGALVLYHLLTHPNGVDAAVVTSPGLIPANPPSAATLFMARLLANILPAGTINNQLDLTGLSRDPQVVQAYRSDPLTHDRVSFALGLDLIEKGKWILENAASLSVPTLLMVGSADRLVNPDPVIRFAQASPRCTTYKLWDGFYHELHNEPEKDIVFQTLLDWVVSVLNLQSGGGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7P5</accession>
    <name>A0A0P6X7P5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Signal peptidase I</fullName>
            <ecNumber evidence="3 5">3.4.21.89</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_03960</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>Cleavage of hydrophobic, N-terminal signal or leader sequences from secreted and periplasmic proteins.</text>
            <dbReference type="EC" id="3.4.21.89"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Membrane</location>
            <topology evidence="5">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the peptidase S26 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.89" evidence="3 5"/>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061665.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03960"/>
    <dbReference type="EnsemblBacteria" id="KPL79048">
        <property type="protein sequence ID" value="KPL79048"/>
        <property type="gene ID" value="ADN00_03960"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.147"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006465">
        <property type="term" value="P:signal peptide processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06530">
        <property type="entry name" value="S26_SPase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000223">
        <property type="entry name" value="Pept_S26A_signal_pept_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019758">
        <property type="entry name" value="Pept_S26A_signal_pept_1_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019757">
        <property type="entry name" value="Pept_S26A_signal_pept_1_Lys-AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019533">
        <property type="entry name" value="Peptidase_S26"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43390">
        <property type="entry name" value="PTHR43390"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10502">
        <property type="entry name" value="Peptidase_S26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00727">
        <property type="entry name" value="LEADERPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="SSF51306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02227">
        <property type="entry name" value="sigpep_I_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00760">
        <property type="entry name" value="SPASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00761">
        <property type="entry name" value="SPASE_I_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="27"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S26" evidence="6">
        <location>
            <begin position="29"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR600223-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF10502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL79048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="198" mass="22312" checksum="231B435B71AA58C5" modified="2016-01-20" version="1">MTEINPNQETDSAAEKLPGTKSNTARVIIEALQTIVLALVLYFLIDSFMARVRVDKISMRPTLEPGQLLLVNKTAYRFGEVQRGDIVVFHYPLNPAEDYIKRVIGVPGDTVVVENGQVFVNGQELVEDYIADAPTYTGEWEVPEEMYFVLGDNRNQSSDSHRWGFVPEDLMLGKAIFVYWPIDKIKTLNHPLVVNAAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X980</accession>
    <name>A0A0P6X980_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_17880</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000043">
        <property type="protein sequence ID" value="KPL70903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064406.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000043.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70903">
        <property type="protein sequence ID" value="KPL70903"/>
        <property type="gene ID" value="ADN00_17880"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="SSF48239"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="339" mass="37497" checksum="6A7E2A702632622E" modified="2016-01-20" version="1">MPWLNHLSGDPLTWLLEPEEPAARFLALRDLQDLPEDHPDCQTTRAAAHQQGPIPAILEQMNPEGYWIEPGGGYNPKYRSTVWSLILLAQLGASARLDERIQRACAYQIDHSLSPNGPFGGSPNAPSSTVDCLQGNLCWALVRLGCRDERLNKAYEWMARSVTGEGVAPASERDAPLRYYAGKCGPNFACGANDKQSCAWGAAKVMLAFSVCPPQARTPLVERAIQQGIDFLFSVDPATAAYPSGYTGKPSTSWWKFGFPVFYITDILQIAEALAAHGCAKDPRLANTLQLILSKQGADGRWSLEYDYRGKTWLEWGEKKQPNKWVTLRALRVIKAAFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9I1</accession>
    <name>A0A0P6X9I1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 10">Adenylosuccinate lyase</fullName>
            <shortName evidence="10">ASL</shortName>
            <ecNumber evidence="4 10">4.3.2.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9 10">Adenylosuccinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">ADN00_05695</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>(2S)-2-[5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamido]succinate = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + fumarate</text>
            <dbReference type="Rhea" id="RHEA:23920"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:58443"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="EC" id="4.3.2.2"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="7">
            <dbReference type="Rhea" id="RHEA:23921"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>N(6)-(1,2-dicarboxyethyl)-AMP = AMP + fumarate</text>
            <dbReference type="Rhea" id="RHEA:16853"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:57567"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="4.3.2.2"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="8">
            <dbReference type="Rhea" id="RHEA:16854"/>
        </physiologicalReaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 10">Purine metabolism; AMP biosynthesis via de novo pathway; AMP from IMP: step 2/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 10">Purine metabolism; IMP biosynthesis via de novo pathway; 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxylate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.2" evidence="4 10"/>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062004.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05695"/>
    <dbReference type="EnsemblBacteria" id="KPL78734">
        <property type="protein sequence ID" value="KPL78734"/>
        <property type="gene ID" value="ADN00_05695"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1615"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00132"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00075">
        <property type="reaction ID" value="UER00336"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070626">
        <property type="term" value="F:(S)-2-(5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamido) succinate lyase (fumarate-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004018">
        <property type="term" value="F:N6-(1,2-dicarboxyethyl)AMP AMP-lyase (fumarate-forming) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044208">
        <property type="term" value="P:'de novo' AMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019468">
        <property type="entry name" value="AdenyloSucc_lyase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004769">
        <property type="entry name" value="Pur_lyase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10397">
        <property type="entry name" value="ADSL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00998">
        <property type="entry name" value="ADSL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00928">
        <property type="entry name" value="purB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 12" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 10" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ADSL_C" evidence="11">
        <location>
            <begin position="369"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00024477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00024487"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00030717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU361172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KPL78734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="462" mass="51539" checksum="8B5956603A03EF3A" modified="2016-01-20" version="1">MPDYDLYQSPFTWRYASPEMRGIWSEHHKRLLWRRIWVALAKTQQGFGLVSAEQLADIEAHVSDIDVPRALDIEAEIHHDLMAELKTFAEQCPTGGGILHMGATSMDIEDNADALRMREALDCVLGRLKELLLAFAEKIEQTADLPVIAFTHIQPAEPSTLGYRLASYAQDLLEDWLRLSTQYAQLRGKGFKGAVGTAAAYADLIGLDALEAFEARLSQLLDLPFYPVATQTYPRKQDYEVISALAGLGGSVYKLAFDLRLLQSPPIGELSEPFAKKQVGSSAMPFKRNPINAEKMDSLARALAVMPQVAWGNAAHSLLERTLDDSANRRSMLPEAFLITDELLRTALRVVKGLNIREESIQKNLDAYAPFAATERLMMAAVKKGADRQAMHERLREHALAAWQAVQQGAANPLLERIKEDALFQQMLTDAEMESLFDVSAYVGSAPQRARELARRIHNLLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9L8</accession>
    <name>A0A0P6X9L8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF1801 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10015</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062862.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10015"/>
    <dbReference type="EnsemblBacteria" id="KPL76923">
        <property type="protein sequence ID" value="KPL76923"/>
        <property type="gene ID" value="ADN00_10015"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2464"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014922">
        <property type="entry name" value="DUF1801"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08818">
        <property type="entry name" value="DUF1801"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1801" evidence="1">
        <location>
            <begin position="20"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="124" mass="13707" checksum="D1727AE2D6640273" modified="2016-01-20" version="1">MQVNPLTIDAYIAGCPAAVQPLLQKIRETIRQAAPEAQEKISYGMPTFYLHGNLVHFAAHKKHIGFYPAPSGIEAYSEALAPYETSKGAVQFPLEQPIPFDLIREITLFRVGENQAKAAAKKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9U3</accession>
    <name>A0A0P6X9U3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Radical SAM core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_06295</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062112.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06295"/>
    <dbReference type="EnsemblBacteria" id="KPL78825">
        <property type="protein sequence ID" value="KPL78825"/>
        <property type="gene ID" value="ADN00_06295"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1761"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040084">
        <property type="entry name" value="GTPase_Obg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01083">
        <property type="entry name" value="Uncharacterised_Radical_SAM_Su"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="6">
        <location>
            <begin position="10"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL78825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="313" mass="35177" checksum="127F2F7F9E095BEA" modified="2016-01-20" version="1">MIAFGPVPSRRLGHSLGINHIPPKHCPYSCVYCQVGRTTALTLKRRVFYPLAQILREVEEKIASSRQLGLPIDYLTLVPDGEPTLDLQLGAIIQSLKQFQIPVAVISNAALIDRPEVREELSAADWVSLKVDTVDDLEWKKINRPQGHLVLSALLNGMMDFKRMFSGTLVTETMLVSGINESQDSLQRLAAYLLKLQPSRSFLSIPTRPPAETWVKSPEAGQLGSILEFFAERVPFMDLLFEAEAADFHSTGSFVDDLLAITAVHPIRERALRKMVEQAGEDWSTVERLVAEARMIAIPYREEVFFLRKHAEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XA08</accession>
    <name>A0A0P6XA08_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Response regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_10800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063007.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77041">
        <property type="protein sequence ID" value="KPL77041"/>
        <property type="gene ID" value="ADN00_10800"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2637"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="3"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="271"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="313"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="314"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL77041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="355" mass="38675" checksum="807528BBE6FFF31C" modified="2016-01-20" version="1">MRRVLIVEDAQELGRLLQASLKTLPFPIESVIVPSAEEAMLDARQHPPDLLVTDIRLPGMSGLDLIQKLRDRLPQTRYVVITALAEDEHRIRARKMGVRAYFQKPMELADFLAAVTAALEVSESEFESESPRGAEKTLRPPHNAFSISEWLANLRAGLKAQAVLVLDDHGRITGQAGDFPSPDVEQRWIPAMMAANSSHHRLAHMLGEAHPHSLQVFAGREFDLFLAPVGDYALVLVFGVGSAASFTAQVYGQILEAQLALVESFSQVGAHFQQEEPSAPAPAAEEAGEAPEEDNLSALEALLANPGESLQVQDADAFWQNTNGEPSSGRVTLPGAISYEQARQLGLLPKDAQEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XA58</accession>
    <name>A0A0P6XA58_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_16295</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72043">
        <property type="protein sequence ID" value="KPL72043"/>
        <property type="gene ID" value="ADN00_16295"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3696"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="194" mass="21364" checksum="E533C3DC0C5C7E69" modified="2016-01-20" version="1">MKVCEMKNFLEKAQLYAIILGVIGFIMGIVNIVKGRTEFILPSFALFGVGALAVVIPTAISKFSDQNANRNPHSQHPVIANIPAEKPITVLGMVVLLERPLRFANDEEALIKSIFDQQRLELKRAIAPSAQVKMIVAGSSLDDDAYIYGICRSTFDSLDSYADNDEFLSRVATGSFVASDGNRGKHFAFLNRRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAM2</accession>
    <name>A0A0P6XAM2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_02215</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000009">
        <property type="protein sequence ID" value="KPL79798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061330.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000009.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79798">
        <property type="protein sequence ID" value="KPL79798"/>
        <property type="gene ID" value="ADN00_02215"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="75"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="78" mass="8649" checksum="3260E3A81F57FE79" modified="2016-01-20" version="1">MNSIFAFCMLFLVVPVGLNMIRRVFAILYGPESDSDYHQQLYQQAVRAGVIEIVVSLVGLALAGWVVFSLSRAFISLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBD3</accession>
    <name>A0A0P6XBD3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AAA_28 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09640</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77063">
        <property type="protein sequence ID" value="KPL77063"/>
        <property type="gene ID" value="ADN00_09640"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038727">
        <property type="entry name" value="NadR/Ttd14_AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13521">
        <property type="entry name" value="AAA_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_28" evidence="1">
        <location>
            <begin position="2"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="172" mass="19660" checksum="67813884C9F2697C" modified="2016-01-20" version="1">MITGAPSCGKTTLLDLLADKGYKTIPESARQYMEGELAKGRTIQEVHANAAALQALFFKIQFEVERELPADELFFLDGAVPGSLAWFRLFGRNPNEILPECFHHRYAAVFILDRLPLKQNGFRFEELGQIDFLDDWITRDYTALGYDVVRVPVLPPQERLTFLLQRLNEKGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBI4</accession>
    <name>A0A0P6XBI4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_08645</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000022">
        <property type="protein sequence ID" value="KPL77654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062595.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000022.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77654">
        <property type="protein sequence ID" value="KPL77654"/>
        <property type="gene ID" value="ADN00_08645"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033764">
        <property type="entry name" value="Sdr_B"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17210">
        <property type="entry name" value="SdrD_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="SSF54106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132966" description="LysM domain-containing protein" evidence="3">
        <location>
            <begin position="27"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="233"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="4">
        <location>
            <begin position="46"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL77654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="258" mass="27243" checksum="F3446663EE190456" modified="2016-01-20" version="1">MKKRLFLLTSLILTGLLALLAAPVTATPQQPQAFYQTPTPGADGRIIYIVKPGDSCLSISLLTGVELNDLRLLNNLDEECLLTEGKQLLLGVVTEPTVTPGPSPTPTQALPTPTPFNGSGEICVFLFEDLNGNALAEELELSIAGGAVSITDREGEVSLTGETTTDPEPLCFSELAEGEYNISVAPPEGYNPTTAMNYPLILRAGDRSILDFGAQLSSEAQPLAPSEGGRSPVMAIVGGLLLLGGIGLGVYFWRARKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBT2</accession>
    <name>A0A0P6XBT2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltranfer_dom domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_02330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000010">
        <property type="protein sequence ID" value="KPL79676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02330"/>
    <dbReference type="EnsemblBacteria" id="KPL79676">
        <property type="protein sequence ID" value="KPL79676"/>
        <property type="gene ID" value="ADN00_02330"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026669">
        <property type="entry name" value="Arsenite_MeTrfase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43675">
        <property type="entry name" value="PTHR43675"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltranfer_dom" evidence="1">
        <location>
            <begin position="87"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="263" mass="27396" checksum="61CD7422D0122F30" modified="2016-01-20" version="1">MASATRRRPVRDAVRDNYAALARSGSNCCGSSSLIENASCCAPAKMDTSEITFVVEYSQEELSEAPAEAAEFTLGCGNPLALAGLQAGETVLDIGSGGGLDAFLAARKVGPGGWVIGVDMTPSMLDRARAAAERSGISNVEFRQGYAEALPVESNAVDVILSNCVINLSEDKGQVFREAYRVLRPGGRLEVSDVVAAAALPASLQENTAEWAECVSGALPEAEYLDLLAQAGFTKITVRRSASLGRAGGVSVYSALVAAYKPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XCX1</accession>
    <name>A0A0P6XCX1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_01315</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061159.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01315"/>
    <dbReference type="EnsemblBacteria" id="KPL80517">
        <property type="protein sequence ID" value="KPL80517"/>
        <property type="gene ID" value="ADN00_01315"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009297">
        <property type="entry name" value="DUF952"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34129">
        <property type="entry name" value="PTHR34129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06108">
        <property type="entry name" value="DUF952"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL80517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="120" mass="13389" checksum="FCDF98D4CAB1E77F" modified="2016-01-20" version="1">MNTDPIYHITTRSDWRKARSSMLYHPSSLESEGFIHCSALNQVCSSARRHFYGQTGLVLLEIDPTVSGMKVQWENTTGGEELFPHLYGPLPVRAVLRVYDFPPNPDGNFSLPAGLPARGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XD02</accession>
    <name>A0A0P6XD02_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH gntR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01725</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80599">
        <property type="protein sequence ID" value="KPL80599"/>
        <property type="gene ID" value="ADN00_01725"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="1">
        <location>
            <begin position="12"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="145" mass="16359" checksum="FF1BF156EBCD48B8" modified="2016-01-20" version="1">MDKIYIDFQSGVPIYVQLMEQIENLVMGGQLKPGDQMPTVRQLAAELGVNFNTVARAYRLMDEAGIISTQQGRGTYILAPEKLEETQLLKMEVLDWLTQRFFADAAYKGFSLEEIRAAFEKEWSDWMSRRDLAAGADAPQDTSSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDE6</accession>
    <name>A0A0P6XDE6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glutamine ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">glnQ</name>
        <name evidence="5" type="ORF">ADN00_01095</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000003">
        <property type="protein sequence ID" value="KPL80819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01095"/>
    <dbReference type="EnsemblBacteria" id="KPL80819">
        <property type="protein sequence ID" value="KPL80819"/>
        <property type="gene ID" value="ADN00_01095"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1963"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015424">
        <property type="term" value="F:ABC-type amino acid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030679">
        <property type="entry name" value="ABC_ATPase_HisP-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039085">
        <property type="entry name" value="ABC_ATPase_HisP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="6"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL80819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="259" mass="29003" checksum="7DD8BF183DC1AB19" modified="2016-01-20" version="1">MEKTILRIENLSKSYGHTTILKDITLDINEGDTVVIIGPSGTGKSTMLRCINLLTKPNSGRIFLDGKEINAHGVDENEVRKHIGMVFQDFLLFNHLTALDNVMIGPLKVLKMDPAQARLKAMFELERVGLKDKANLYPGQLSGGQKQRVGIARALAMDPRIMLFDEPTSALDPELIGEVLEVMRKLASEGMTMLVVTHEMGFAREVADKIVFMESGVVVEEGPPDDLFQHPKHNRTREFLWKITELYGKHDQDKPGEPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDG9</accession>
    <name>A0A0P6XDG9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_00110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL80996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060926.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00110"/>
    <dbReference type="EnsemblBacteria" id="KPL80996">
        <property type="protein sequence ID" value="KPL80996"/>
        <property type="gene ID" value="ADN00_00110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018580">
        <property type="entry name" value="Uncharacterised_YfhO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38454">
        <property type="entry name" value="PTHR38454"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09586">
        <property type="entry name" value="YfhO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="156"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="239"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="312"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="342"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="378"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="410"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="440"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="752"/>
            <end position="770"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="781" mass="86764" checksum="C5DAE3205A06F8F6" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDK0</accession>
    <name>A0A0P6XDK0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PQQ_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_00430</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060981.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00430"/>
    <dbReference type="EnsemblBacteria" id="KPL81041">
        <property type="protein sequence ID" value="KPL81041"/>
        <property type="gene ID" value="ADN00_00430"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025666">
        <property type="entry name" value="PQQ-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_beta_propeller_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13360">
        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13570">
        <property type="entry name" value="PQQ_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132989" description="PQQ_3 domain-containing protein" evidence="1">
        <location>
            <begin position="30"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="domain" description="PQQ_3" evidence="2">
        <location>
            <begin position="73"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13570"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL81041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="941" mass="105549" checksum="EF082C540F632506" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XEI6</accession>
    <name>A0A0P6XEI6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Y1_Tnp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_14605</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000035">
        <property type="protein sequence ID" value="KPL73569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063769.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000035.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14605"/>
    <dbReference type="EnsemblBacteria" id="KPL73569">
        <property type="protein sequence ID" value="KPL73569"/>
        <property type="gene ID" value="ADN00_14605"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2087"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002686">
        <property type="entry name" value="Transposase_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036515">
        <property type="entry name" value="Transposase_17_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM01321">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143422">
        <property type="entry name" value="SSF143422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Y1_Tnp" evidence="1">
        <location>
            <begin position="26"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL73569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="186" mass="21895" checksum="D8D60777110D8452" modified="2016-01-20" version="1">MGESVLSLDLRKHRRHSIRYPGYDYSLAGGYFVTIVTYQRRNLFGQIDRDHMVLSRLGMLAKNEWLRSAEIRKEIRLFEDEMVIMPNHLHGIVWIEQVNDCPMPLSGDVHPYPNGFLQKRGLLGSFIAGFKTGVSMVARRESDVLKVWQRNYYGHIIRNDTEYDRIMAYIQDNPRRWQEDELFGMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XFY4</accession>
    <name>A0A0P6XFY4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MannoseP_isomer domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_14085</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063666.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000033.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14085"/>
    <dbReference type="EnsemblBacteria" id="KPL74127">
        <property type="protein sequence ID" value="KPL74127"/>
        <property type="gene ID" value="ADN00_14085"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005976">
        <property type="term" value="P:polysaccharide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001538">
        <property type="entry name" value="Man6P_isomerase-2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01050">
        <property type="entry name" value="MannoseP_isomer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MannoseP_isomer" evidence="1">
        <location>
            <begin position="7"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="117" mass="13470" checksum="15CDAAC2E1206009" modified="2016-01-20" version="1">MIDSDNRPWGRWEEYLNEPGYRVKRIIVNPGKRLSLQLHHLRAEHWAVVQGSGLVTVGDEVRAVRRGDAIYIDKGQVHRIENNGEDFLVFIETQYGICVEDDIVRLEDDWGRTSPGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGU6</accession>
    <name>A0A0P6XGU6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_03515</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061582.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03515"/>
    <dbReference type="EnsemblBacteria" id="KPL78974">
        <property type="protein sequence ID" value="KPL78974"/>
        <property type="gene ID" value="ADN00_03515"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009097">
        <property type="entry name" value="Cyclic_Pdiesterase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55144">
        <property type="entry name" value="SSF55144"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="180" mass="20213" checksum="CC100F770AA5486E" modified="2016-01-20" version="1">MHGLVSLLPQPFYHEVELLWDELERECGLVGVRQTPFPHFSWTASESVSESALQAKLNRLARQIKPFAISTAGVGIFPGEKPVVFIRVVKSPALFSLHETILAAVREPLGGTLSPLYEPDVWVPHITLAYEDVSEENLAAVVRMLAGRDLHWKMQIDNLAFILHRPGTSAEMKFVQRFQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XI36</accession>
    <name>A0A0P6XI36_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_17990</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000044">
        <property type="protein sequence ID" value="KPL70767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064430.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000044.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17990"/>
    <dbReference type="EnsemblBacteria" id="KPL70767">
        <property type="protein sequence ID" value="KPL70767"/>
        <property type="gene ID" value="ADN00_17990"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011460">
        <property type="entry name" value="DUF1566"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07603">
        <property type="entry name" value="DUF1566"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="394" mass="43598" checksum="02011FDC1AF1BFA6" modified="2016-01-20" version="1">MMLKDNGDGTISDSCTGLMWQQAENAEEMNYEDAVAFCKNLILAGNSDWRLPTKEELVALAQIGDEPLRTFFLELQQERYWAFTRRSELGWAESPDRIAYTVDFDPDSGNYCRPTTYFRVYKYFVRGVRTGGKSQPIKSEVVSSNEALRTLRARVERLGIDHPRQQRPDLDPQLDMQLPWIARTLEEAATALESGRDPFGNPITDAQVISGLRKLVQMVCDNRFLSAMDLGHPGIHTALQRCMAELEVIIHGIEGHPPAASPPPASKGVKTLISLCTKMGILFPNQYVNQAVEELMQEGEPGSRALALLIRELMECRSPKITHALAAAGRIAPTPELVDAVRAVAEAPELTEAPDHPSFTPEITGGGRVGWTSGTHRKVVGKALQAEELLKGHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XJL7</accession>
    <name>A0A0P6XJL7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SAM_MT_RSMB_NOP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_17530</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71480.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064345.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17530"/>
    <dbReference type="EnsemblBacteria" id="KPL71480">
        <property type="protein sequence ID" value="KPL71480"/>
        <property type="gene ID" value="ADN00_17530"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001510">
        <property type="term" value="P:RNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031341">
        <property type="entry name" value="Methyltr_RsmF_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001678">
        <property type="entry name" value="MeTrfase_RsmB/NOP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023267">
        <property type="entry name" value="RCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22807">
        <property type="entry name" value="PTHR22807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01189">
        <property type="entry name" value="Methyltr_RsmB-F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17125">
        <property type="entry name" value="Methyltr_RsmF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR02008">
        <property type="entry name" value="RCMTFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51686">
        <property type="entry name" value="SAM_MT_RSMB_NOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SAM_MT_RSMB_NOP" evidence="5">
        <location>
            <begin position="37"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="253"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="200"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51686"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL71480.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="497" mass="55618" checksum="CE9F79B3AC68D582" modified="2016-01-20" version="1">MARRKKKNTSPLPSQSAEQAALQRFAPLLDEQDYAALLQDLERPLSTAIRANPLKADPQADAARWAQQYGWRLDPVPFCPTGWWVSEAQTPPSQTIEHRMGAYYIQDAASMLPVELFDLRPDPEQLILDLAASPGGKTTHLISRAGDQGLVLANDASRERITALRLVLQNWGSLNQAVLRFQAEQYGRWFPETFDRVLLDAPCSMQGLRTSESHPSRPISDREVQQLARRQTRMLESALQALKTGGQVVYSTCTLTPEEDELVLDALLKEYPGGLRVEDTRARLPLPAPALRRVGEQLLDGQVSGAARIWPHRYHTAGFFAALITKTGPIGRREAQPPERPLEVFGLDALDADELDDLAARFNDEYGFNLHAMLQENRCELRQKGAAVFIVPELYTRHFASLPFQSLGMMLGEFSPDGFVPSHEWLARFYRFFAGGRVRLDSGQAQAWLRGEDASVQPGGVPVLAVIDEQGRYIGRGKYSDGKLKNLLPRRLVWMQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XJN4</accession>
    <name>A0A0P6XJN4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Vitamin B12-dependent ribonucleotide reductase</fullName>
            <ecNumber evidence="11">1.17.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">ADN00_13135</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>[thioredoxin]-disulfide + a 2'-deoxyribonucleoside 5'-diphosphate + H2O = [thioredoxin]-dithiol + a ribonucleoside 5'-diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23252"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:73316"/>
            <dbReference type="EC" id="1.17.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 11">
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Genetic information processing; DNA replication.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 11">Belongs to the ribonucleoside diphosphate reductase class-2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.17.4.1" evidence="11"/>
    <dbReference type="EMBL" id="LGCL01000030">
        <property type="protein sequence ID" value="KPL75182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13135"/>
    <dbReference type="EnsemblBacteria" id="KPL75182">
        <property type="protein sequence ID" value="KPL75182"/>
        <property type="gene ID" value="ADN00_13135"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2877"/>
    <dbReference type="UniPathway" id="UPA00326"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004748">
        <property type="term" value="F:ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd02888">
        <property type="entry name" value="RNR_II_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013346">
        <property type="entry name" value="NrdE_NrdA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000788">
        <property type="entry name" value="RNR_lg_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013509">
        <property type="entry name" value="RNR_lsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013344">
        <property type="entry name" value="RNR_NrdJ/NrdZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008926">
        <property type="entry name" value="RNR_R1-su_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02867">
        <property type="entry name" value="Ribonuc_red_lgC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00317">
        <property type="entry name" value="Ribonuc_red_lgN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01183">
        <property type="entry name" value="RIBORDTASEM1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48168">
        <property type="entry name" value="SSF48168"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02506">
        <property type="entry name" value="NrdE_NrdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02504">
        <property type="entry name" value="NrdJ_Z"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0846">Cobalamin</keyword>
    <keyword evidence="10 11" id="KW-0170">Cobalt</keyword>
    <keyword evidence="9" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0235">DNA replication</keyword>
    <keyword evidence="6 11" id="KW-0237">DNA synthesis</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ribonuc_red_lgN" evidence="13">
        <location>
            <begin position="9"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="RIBORED_LARGE" evidence="14">
        <location>
            <begin position="91"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="781"/>
            <end position="800"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU364064"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF02867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KPL75182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="840" mass="92121" checksum="A4416BAE6FDBC453" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKS6</accession>
    <name>A0A0P6XKS6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12 13 14">UvrABC system protein B</fullName>
            <shortName evidence="13">Protein UvrB</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Excinuclease ABC subunit B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">uvrB</name>
        <name evidence="19" type="ORF">ADN00_01230</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 13">The UvrABC repair system catalyzes the recognition and processing of DNA lesions. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. Upon binding of the UvrA(2)B(2) complex to a putative damaged site, the DNA wraps around one UvrB monomer. DNA wrap is dependent on ATP binding by UvrB and probably causes local melting of the DNA helix, facilitating insertion of UvrB beta-hairpin between the DNA strands. Then UvrB probes one DNA strand for the presence of a lesion. If a lesion is found the UvrA subunits dissociate and the UvrB-DNA preincision complex is formed. This complex is subsequently bound by UvrC and the second UvrB is released. If no lesion is found, the DNA wraps around the other UvrB subunit that will check the other stand for damage.</text>
    </comment>
    <comment type="subunit">
        <text evidence="11 13 14">Forms a heterotetramer with UvrA during the search for lesions. Interacts with UvrC in an incision complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13 14">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="13">The beta-hairpin motif is involved in DNA binding.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 13 14">Belongs to the UvrB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000003">
        <property type="protein sequence ID" value="KPL80839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061142.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01230"/>
    <dbReference type="EnsemblBacteria" id="KPL80839">
        <property type="protein sequence ID" value="KPL80839"/>
        <property type="gene ID" value="ADN00_01230"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1994"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009380">
        <property type="term" value="C:excinuclease repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009381">
        <property type="term" value="F:excinuclease ABC activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00204">
        <property type="entry name" value="UvrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006935">
        <property type="entry name" value="Helicase/UvrB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001943">
        <property type="entry name" value="UVR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036876">
        <property type="entry name" value="UVR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004807">
        <property type="entry name" value="UvrB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041471">
        <property type="entry name" value="UvrB_inter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024759">
        <property type="entry name" value="UvrB_YAD/RRR_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24029">
        <property type="entry name" value="PTHR24029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04851">
        <property type="entry name" value="ResIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12344">
        <property type="entry name" value="UvrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17757">
        <property type="entry name" value="UvrB_inter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46600">
        <property type="entry name" value="SSF46600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00631">
        <property type="entry name" value="uvrb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="15" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 13 14" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 13 14" id="KW-0228">DNA excision</keyword>
    <keyword evidence="9 13 14" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8 13 14" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="4 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="13 14" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="17">
        <location>
            <begin position="24"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="18">
        <location>
            <begin position="428"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="domain" description="UVR" evidence="16">
        <location>
            <begin position="626"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="248"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="15">
        <location>
            <begin position="622"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Beta-hairpin" evidence="13">
        <location>
            <begin position="90"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00025647"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00026033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KPL80839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="684" mass="78149" checksum="765078F34CFD920D" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XL32</accession>
    <name>A0A0P6XL32_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_09925</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062844.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09925"/>
    <dbReference type="EnsemblBacteria" id="KPL76907">
        <property type="protein sequence ID" value="KPL76907"/>
        <property type="gene ID" value="ADN00_09925"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="Phage_T4_Gp19"/>
    </dbReference>
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        <property type="entry name" value="Phage_T4_gp19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="177" mass="19741" checksum="3EEF6BA0651ED189" modified="2016-01-20" version="1">MTDGLYRAIPKSQYTLYEVVEGKPPRALGAFDSFTGGDQVISMVHYNVMDEHGNVTTKFIPGQTTFEPVVLLRPMDIVAKAIYKRFWKAVAGQLTTIKKNYSVSMNDSQGEPLVYWHLANALPVKVSGFDFNMTTESEYTSFEISLQAESIEVEFTKAAKPKVVSEALDAWDEAENG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XL57</accession>
    <name>A0A0P6XL57_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062899.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76952">
        <property type="protein sequence ID" value="KPL76952"/>
        <property type="gene ID" value="ADN00_10205"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021214">
        <property type="entry name" value="DUF2568"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10823">
        <property type="entry name" value="DUF2568"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="121" mass="13072" checksum="3A179B480DB253F1" modified="2016-01-20" version="1">MSQNPLNLGLRFALELAALAAMGVWGWRAAQGWPRFLLAVGIPLLAAALWGIFRVPNDPGSAPVAVPGLLRLALELAYFGFAVWALYNASLPALAWSLAAALIVHYALSYDRVLWMLAQRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XM60</accession>
    <name>A0A0P6XM60_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_18200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064473.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70000">
        <property type="protein sequence ID" value="KPL70000"/>
        <property type="gene ID" value="ADN00_18200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="86" mass="10128" checksum="C1BFA87693A5B3BB" modified="2016-01-20" version="1">MYKELAEAVEQFLQDVTPESLEKEIWELIRKSPDPDGGIDAYRLIRHFLGQPGLNNIQTGWAYQRIRPVFKQLFEHIPSLYYFTGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XML1</accession>
    <name>A0A0P6XML1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH arsR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_18220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064659.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70165">
        <property type="protein sequence ID" value="KPL70165"/>
        <property type="gene ID" value="ADN00_18220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="6"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="130" mass="14708" checksum="69E164EDCDD1E0FC" modified="2016-01-20" version="1">MNINQEGTNPFAQPAQLLKLLAHPARLQILEILRNGEECVCHMEALLGYRQAYLSQQLAVLREAGFLEDRREGWNIYYRVVRPEVFSVLAAVYAMLDGPKQQPVFELKGAVCSCPKCEVTQHIAKGDHIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XMM6</accession>
    <name>A0A0P6XMM6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Aldehyde reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_00825</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the iron-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061051.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00825"/>
    <dbReference type="EnsemblBacteria" id="KPL81101">
        <property type="protein sequence ID" value="KPL81101"/>
        <property type="gene ID" value="ADN00_00825"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3563"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990362">
        <property type="term" value="F:butanol dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08187">
        <property type="entry name" value="BDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001670">
        <property type="entry name" value="ADH_Fe/GldA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044731">
        <property type="entry name" value="BDH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43633">
        <property type="entry name" value="PTHR43633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00465">
        <property type="entry name" value="Fe-ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-ADH" evidence="3">
        <location>
            <begin position="9"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL81101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="385" mass="42571" checksum="B3067F790A52683A" modified="2016-01-20" version="1">MDNFSFYNPTRIVFGKGSIANLPTQLATDQSILMLYGGGSIKKNFIYNDVKAALAGYRVIEFGGVPSNPEYEVCMQAADVVLREKIGFILAVGGGSVIDAAKFIAAVARNPQVEAWDIVSKKAPLRGALPIGVVLTLAATGSEMNNISVISRKSTQEKYAFSSDALYPQFSILDPQTTYTLPVEQIRNGLVDAFIHAGEQYMTFPNRNPLVDRQAEAIFSTLIEIAQDALRTPADYDARAAYMWCATQALNGHLRCGAPQDWATHRIGHELTALYGLAHAESLAPIWISLLRYKLEDKMEKLAQYGRRLWNLKMPDPRALAGQAIDRTEAFFNSIGMPTHLREFGVDAEAAAREIEHRFTERNVVWGENQDITPEVSAEIVRQAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XN37</accession>
    <name>A0A0P6XN37_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7 8">Transcription elongation factor GreA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Transcript cleavage factor GreA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">greA</name>
        <name evidence="11" type="ORF">ADN00_08290</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7 8">Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the GreA/GreB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08290"/>
    <dbReference type="EnsemblBacteria" id="KPL77867">
        <property type="protein sequence ID" value="KPL77867"/>
        <property type="gene ID" value="ADN00_08290"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.660"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070063">
        <property type="term" value="F:RNA polymerase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032784">
        <property type="term" value="P:regulation of DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00105">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036953">
        <property type="entry name" value="GreA/GreB_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018151">
        <property type="entry name" value="TF_GreA/GreB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006359">
        <property type="entry name" value="Tscrpt_elong_fac_GreA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028624">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001437">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023459">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022691">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036805">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30437">
        <property type="entry name" value="PTHR30437"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01272">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03449">
        <property type="entry name" value="GreA_GreB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006092">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46557">
        <property type="entry name" value="SSF46557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01462">
        <property type="entry name" value="greA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00829">
        <property type="entry name" value="GREAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00830">
        <property type="entry name" value="GREAB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="11" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 7 8" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="GreA_GreB_N" evidence="10">
        <location>
            <begin position="6"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="domain" description="GreA_GreB" evidence="9">
        <location>
            <begin position="83"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL77867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="156" mass="17432" checksum="23A780B95184373E" modified="2016-01-20" version="1">MMTLVNYLTAEGAARLQEELAELKGPRREDLATRLRIAIEQGDLSENADYIAAKEEQGFLEGRIQELENILANTKIIDEMEQDKNIVGIGDHVTIQEDDYEPETYYLVGPKEADPRNGRISHESPIGRALIGHRVGEAVEVDTPGGKVIFKIMEIN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XP17</accession>
    <name>A0A0P6XP17_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Inorganic diphosphatase</fullName>
            <ecNumber evidence="2">3.6.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_10540</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.1" evidence="2"/>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062960.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10540"/>
    <dbReference type="EnsemblBacteria" id="KPL77001">
        <property type="protein sequence ID" value="KPL77001"/>
        <property type="gene ID" value="ADN00_10540"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2579"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006796">
        <property type="term" value="P:phosphate-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00412">
        <property type="entry name" value="pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008162">
        <property type="entry name" value="Pyrophosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036649">
        <property type="entry name" value="Pyrophosphatase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10286">
        <property type="entry name" value="PTHR10286"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00719">
        <property type="entry name" value="Pyrophosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50324">
        <property type="entry name" value="SSF50324"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL77001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="202" mass="22796" checksum="19D8388587B309F6" modified="2016-01-20" version="1">MFPKPFFRWRPHPWHGLDVGPKPPKLVNAYIEITPYDLVKYEIDKTTGYVRIDRPQRTSSQPPTLYGFIPRTYCGERLHALSPVSTKGDGDPLDICVISERPIARAEILLTARVVGGIQMVDRGEADDKIVAVMDNDTFWSGVTDISQIPHVLIDRLVHYFSTYKLVKGEDIKVSIEQVYGAEHALKAVSACMQDYEDMFGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XP89</accession>
    <name>A0A0P6XP89_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_17740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000043">
        <property type="protein sequence ID" value="KPL70887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064388.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000043.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17740"/>
    <dbReference type="EnsemblBacteria" id="KPL70887">
        <property type="protein sequence ID" value="KPL70887"/>
        <property type="gene ID" value="ADN00_17740"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="38"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="178" mass="19681" checksum="5913851908C14650" modified="2016-01-20" version="1">MKFTITGSQTHYRGRAFSVEKVDFTLPDGRQASYDLVRHNDSVSIVPVDEHGRILFVSQYRLGAENLLLELPAGVDEDGETPEASAAREIREETGMAAGKLIRLGEYYLAPGYSSELMYAYLATDLTPAPLQADPDEFLQVKAIPIEEAYAMARRGEIQDSKSLAALLLAEPYLRPEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XPR5</accession>
    <name>A0A0P6XPR5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Methionine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_08875</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062642.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08875"/>
    <dbReference type="EnsemblBacteria" id="KPL77248">
        <property type="protein sequence ID" value="KPL77248"/>
        <property type="gene ID" value="ADN00_08875"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4007"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016176">
        <property type="entry name" value="Cbl-dep_enz_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006158">
        <property type="entry name" value="Cobalamin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036724">
        <property type="entry name" value="Cobalamin-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02310">
        <property type="entry name" value="B12-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51703">
        <property type="entry name" value="SSF51703"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52242">
        <property type="entry name" value="SSF52242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51332">
        <property type="entry name" value="B12_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0846">Cobalamin</keyword>
    <keyword evidence="4" id="KW-0170">Cobalt</keyword>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="B12-binding" evidence="5">
        <location>
            <begin position="2"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL77248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="548" mass="60170" checksum="73A27F5183E98BA7" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQ50</accession>
    <name>A0A0P6XQ50_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF4115 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_13895</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13895"/>
    <dbReference type="EnsemblBacteria" id="KPL74379">
        <property type="protein sequence ID" value="KPL74379"/>
        <property type="gene ID" value="ADN00_13895"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1357"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025194">
        <property type="entry name" value="DUF4115"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13464">
        <property type="entry name" value="DUF4115"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="248"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4115" evidence="3">
        <location>
            <begin position="341"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="431"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="438"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL74379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="452" mass="48820" checksum="4D4421D670D59304" modified="2016-01-20" version="1">MGLSIEQVSHALHIRPRYLVALESDDWGDIPSEVQAKGFLRLYADYLKIHLDFTQPAAEPEPQPEPTPPVKQSPLAGMGKIVNRLAEERLTAKKNAEAAAEPPPPPPAVAETPVKIEEPAAVEEPPAPWMEVFREIGSTIAAQREVLGISTADAEKHILIRKHYLDLIEAGEFDRLTSAVQARGMLKNYARFLELNEEAILTRYAEGLQLRHAEKLAQVEKPKPFFTLPTKKAVQDAPAWRRFLTPDLVIMGAIILGLFSFTVWGLARVTAAQSTAAEPTAPPVAEVLAITPSYDATLAITATPIRDVLADDRGQTGSAEGGEIATPTLPVLDDNPLQLYIIAQQRAWMRIVADGKEQFSGRVSPGNVYSFSGEEKMELITGNAAGLRVYYNQTDLGTLGNAGEVVSLLFSAAGILTPTPAASPTLTPTAQPTATLQPTPTVPTPTVTPFIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQG7</accession>
    <name>A0A0P6XQG7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">1-(5-phosphoribosyl)-5-amino-4-imidazole-carboxylate carboxylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_03770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061629.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03770"/>
    <dbReference type="EnsemblBacteria" id="KPL79019">
        <property type="protein sequence ID" value="KPL79019"/>
        <property type="gene ID" value="ADN00_03770"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.107"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039476">
        <property type="entry name" value="P2CMN_synthase_LarB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000031">
        <property type="entry name" value="PurE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43064">
        <property type="entry name" value="PTHR43064"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00731">
        <property type="entry name" value="AIRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01001">
        <property type="entry name" value="AIRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AIRC" evidence="1">
        <location>
            <begin position="120"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="252" mass="27143" checksum="5E23493478C50C72" modified="2016-01-20" version="1">MEENRIKELLESVRSGKVEVDEALDSLVRLPYEQVGDFAQLDMHRGLRRGFPEVVFGQGKTAEQITQIVNRLSERNERVLVTRLSAEVYAQIREELPDDAVYHQRPRALVINRANLVCRPGILVACAGTADTPVAEEAALTAELMGNQVERLYDVGVAGLHRLLDKLPMLRQARVIVVAAGMEGALASVVSGLVDAPVIAVPTSVGYGASFHGLSALLAMLNSCSSGIAVVNIDNGFGAGAMAAMINRLDER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQQ1</accession>
    <name>A0A0P6XQQ1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_04515</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061764.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04515"/>
    <dbReference type="EnsemblBacteria" id="KPL79128">
        <property type="protein sequence ID" value="KPL79128"/>
        <property type="gene ID" value="ADN00_04515"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.260"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015267">
        <property type="term" value="F:channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022357">
        <property type="entry name" value="MIP_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="SSF81338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00221">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="46"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="89"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="123"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="146"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="181"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="232"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL79128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="264" mass="26917" checksum="68D68DD2954CBFA6" modified="2016-01-20" version="1">MKEKGLMSELVGEVFGTFVLLLLGDGVVANVGLAPRLAGTAYNWNTITIGWAFAVIIAVYISGGVSGAHLNPAVTIALAVKRGFPWGKVVPFILAQFVGAFLGALGVFLVYRDGLVAAGMPNVWSTGPGSVFGTTFWGAASSGSTGGYSLVTASIAEIVGTAVLLWGILASGDSKNMGLGNNLGVFIVGFTVLAVGLSLGGPSGYSINPARDLGPRIFGALVGTKGLFDAGFYWLIAPVLMPVVGGILGAATYDLFVTANLPQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XR40</accession>
    <name>A0A0P6XR40_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">NADH dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_16405</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Membrane</location>
            <topology evidence="1 5">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064122.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16405"/>
    <dbReference type="EnsemblBacteria" id="KPL72057">
        <property type="protein sequence ID" value="KPL72057"/>
        <property type="gene ID" value="ADN00_16405"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3723"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001750">
        <property type="entry name" value="ND/Mrp_mem"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001516">
        <property type="entry name" value="Proton_antipo_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00361">
        <property type="entry name" value="Proton_antipo_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00662">
        <property type="entry name" value="Proton_antipo_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="24"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="65"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="102"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="124"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="156"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="257"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="354"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="389"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="436"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="491"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="585"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_N" evidence="8">
        <location>
            <begin position="62"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_M" evidence="7">
        <location>
            <begin position="119"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL72057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="603" mass="64954" checksum="173B900E2263C0C7" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XR56</accession>
    <name>A0A0P6XR56_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13385</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063525.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000031.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13385"/>
    <dbReference type="EnsemblBacteria" id="KPL74827">
        <property type="protein sequence ID" value="KPL74827"/>
        <property type="gene ID" value="ADN00_13385"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.150.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001343">
        <property type="entry name" value="Hemolysn_Ca-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011049">
        <property type="entry name" value="Serralysin-like_metalloprot_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00353">
        <property type="entry name" value="HemolysinCabind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51120">
        <property type="entry name" value="SSF51120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133182" evidence="1">
        <location>
            <begin position="28"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="132" mass="13716" checksum="0B378B909616B5F7" modified="2016-01-20" version="1">MIRKLLLFLAFFHLMGLVFTSMSTASAAANYIPPSHLTSQSFGVNANALKPPQCASINLTTILVGSGRIKGKNRDELILGSPLDDMITSGKKGDDCILGGAGNDDITGNGSSSICIGGPGNDTFHDCSVTIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XR63</accession>
    <name>A0A0P6XR63_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_16675</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064172.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72103">
        <property type="protein sequence ID" value="KPL72103"/>
        <property type="gene ID" value="ADN00_16675"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="200"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="228"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="364"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="407"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="563" mass="64920" checksum="34EFBB045237A650" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XTM5</accession>
    <name>A0A0P6XTM5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_11445</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063148.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11445"/>
    <dbReference type="EnsemblBacteria" id="KPL76564">
        <property type="protein sequence ID" value="KPL76564"/>
        <property type="gene ID" value="ADN00_11445"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.990"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019808">
        <property type="term" value="F:polyamine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015846">
        <property type="term" value="P:polyamine transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001188">
        <property type="entry name" value="Sperm_putr-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00909">
        <property type="entry name" value="SPERMDNBNDNG"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="356" mass="39873" checksum="31E03B65417951F8" modified="2016-01-20" version="1">MKRTRQFLVWISVVLVLSLGLTACGGKGGGSAAKELTVLDWAGYEVPEYRAEFVQQHPDVEVKFTFFADDAEGFAKSKSGFKSDLVHPCTNYWALYVQHGLVQPIDTSRLKYWSGIYPNLAKQGEFDGKQYFIPWDWGYESILVRSDKVKTIPTSWADLWNPEYAGHLSVIDAGENMYMITALSLGLDPWDVSPETVEIIRQKLLELKPNIMHYWADYTELNTLVAGGDIWVAGNAWNDAYTAMLAEGVPVEYVTPKEGRIAWVCGYGISSDIENVDLAYDYLNALMEPAANAQMATDFAYGPGNADSVPLMDQELVQLLELDDPSIIERAILQAPITDEMRQVYTDLWVEIKAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XU94</accession>
    <name>A0A0P6XU94_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ArsR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000006">
        <property type="protein sequence ID" value="KPL80125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061255.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000006.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80125">
        <property type="protein sequence ID" value="KPL80125"/>
        <property type="gene ID" value="ADN00_01820"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3180"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027395">
        <property type="entry name" value="WH_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13601">
        <property type="entry name" value="HTH_34"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_34" evidence="1">
        <location>
            <begin position="21"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="102" mass="11701" checksum="6C44C1A342D09556" modified="2016-01-20" version="1">MKKDDLRDWTEVDRLIHEPARLMILSILAAAEKVDFLFLLNETGLTKGNLSSHLGKLEGAGYIEIEKTYRGKVPQTLISLSETGRQAFEAYRKQLKNMMKYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUJ3</accession>
    <name>A0A0P6XUJ3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nitro_FeMo-Co domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_06275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062108.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06275"/>
    <dbReference type="EnsemblBacteria" id="KPL78821">
        <property type="protein sequence ID" value="KPL78821"/>
        <property type="gene ID" value="ADN00_06275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003731">
        <property type="entry name" value="Di-Nase_FeMo-co_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036105">
        <property type="entry name" value="DiNase_FeMo-co_biosyn_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02579">
        <property type="entry name" value="Nitro_FeMo-Co"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53146">
        <property type="entry name" value="SSF53146"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitro_FeMo-Co" evidence="1">
        <location>
            <begin position="13"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="112" mass="11862" checksum="E47C602F8957D141" modified="2016-01-20" version="1">MIIFISAQEPKLDGAIDERFGRCPYLIKMDTESGQWEALANPGASHSGGAGVAAAQFLIDQKANVAISGDFGPHAASALAAANVEMRLFGDHTSSVQQILSRYEQGLLPAFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XW69</accession>
    <name>A0A0P6XW69_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Sugar-bind domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_02370</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SorC transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000010">
        <property type="protein sequence ID" value="KPL79662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061357.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000010.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79662">
        <property type="protein sequence ID" value="KPL79662"/>
        <property type="gene ID" value="ADN00_02370"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007324">
        <property type="entry name" value="Sugar-bd_dom_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04198">
        <property type="entry name" value="Sugar-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sugar-bind" evidence="2">
        <location>
            <begin position="66"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="320" mass="34443" checksum="C38191C4DD64394B" modified="2016-01-20" version="1">MSRKPEPIDPHLLCRVSTLYYQHHLHQEEISARLGLSRTKIVRLLQQAEAEGIVRVSVRAPEGVYTDLETALEKRYGLREAVVAHVQAGASASELYQDLGETAAGYLTRCLSPGLVIGISWGAALLAMVNALQPQNCPDVTVVQMDGGLGPAGQDAHAFSMCRRLADKLSSQLCLLSVPGVVDSCAVKEAILADRNVQNALRRLDDVQVAFVGIGAPHKDSLLMRDGSIIKPKELEQLLASGVVGDIALRFLNAQGDVVSTPLDERVIGVSVEQLRRVPRLVGVAGGLQKLDVARAALRGGWLDVLITDHHLARCLLADV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XW80</accession>
    <name>A0A0P6XW80_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Polar amino acid ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_01100</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000003">
        <property type="protein sequence ID" value="KPL80820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061120.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01100"/>
    <dbReference type="EnsemblBacteria" id="KPL80820">
        <property type="protein sequence ID" value="KPL80820"/>
        <property type="gene ID" value="ADN00_01100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010065">
        <property type="entry name" value="AA_ABC_transptr_permease_3TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043429">
        <property type="entry name" value="ArtM/GltK/GlnP/TcyL/YhdX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30614">
        <property type="entry name" value="PTHR30614"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01726">
        <property type="entry name" value="HEQRo_perm_3TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0029">Amino-acid transport</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="176"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="7">
        <location>
            <begin position="13"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL80820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="212" mass="23054" checksum="B5113B01B90F9381" modified="2016-01-20" version="1">MVLEIMGYILQGTFITIAVSVVALPMGLLLGMLLALARVYGGKILSSFAAVYSTVMRAVPPIVLLFILYFIIAGSINISPFWAGSIALGIISSSYQLEIMRGAIQSVGSGQMMAARALGMSRVTAIRHIIIPQALRLAIPPWSNEVALVLKDSSLVYAIGVPEILRRAQFVSARTYQPFLAFSVAALIYFLLTFLSNRLLDKVEEKTRIPGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XW82</accession>
    <name>A0A0P6XW82_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_14690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000035">
        <property type="protein sequence ID" value="KPL73584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063785.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000035.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL73584">
        <property type="protein sequence ID" value="KPL73584"/>
        <property type="gene ID" value="ADN00_14690"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2104"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL73584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="170" mass="18261" checksum="52527F45FD1C55B2" modified="2016-01-20" version="1">MNSSNRSSISAGILLILVGAAWLAMRVVPGLSDLIQVEFTWPLIIAGFGLLMLIAGLAAGNAEMAVPACFFMGLGGIFYYQNASGNWASWAYIWTLFPGFVGVGQILAGLFSGKAAEGLREGLRAILTSAIMFFIFGSFLGGMRIFGPYWPVLLILAGLLILIQSFWKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XWM8</accession>
    <name>A0A0P6XWM8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CRISPR system Cms protein Csm4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_14260</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CRISPR-associated Csm4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000034">
        <property type="protein sequence ID" value="KPL73731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063702.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000034.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14260"/>
    <dbReference type="EnsemblBacteria" id="KPL73731">
        <property type="protein sequence ID" value="KPL73731"/>
        <property type="gene ID" value="ADN00_14260"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005510">
        <property type="entry name" value="Csm4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040932">
        <property type="entry name" value="Csm4_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17953">
        <property type="entry name" value="Csm4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01903">
        <property type="entry name" value="cas5_csm4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Csm4_C" evidence="5">
        <location>
            <begin position="248"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL73731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="348" mass="37665" checksum="208B3E09E046413C" modified="2016-01-20" version="1">MQIELWNISGRSFHFGRHGMGQEESAETLTSDSLFAALVSRLAALRGGAAVDAWVRPFLGEQPSFALSSAFPRAGEVRFYPAPLSLKNSAAKPDRVDVKSIKKVRFLSEALFRRVINGEALSQTLYENCLKLNEGRLLCAAEDAPRLPAALRKDGAELWTVEQRPRVTIQRDTNQSTLYFTGQTLFAEGCGLWFGLRWLSEDPALRADLAALLADLGDSGLGGERSSGFGAASIQPAGQVELPHTPGQPWVTLSRYLPRADEISALQSEQAAYTLENVGGWAQSPGKKAERRRAVNLLAEGSVFGGLPRLAPGRVVDTQPDYNGSQPLGHPVWRSGLALAVSLNGEGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XWS1</accession>
    <name>A0A0P6XWS1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_14430</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000034">
        <property type="protein sequence ID" value="KPL73758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL73758">
        <property type="protein sequence ID" value="KPL73758"/>
        <property type="gene ID" value="ADN00_14430"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008897">
        <property type="term" value="F:holo-[acyl-carrier-protein] synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037143">
        <property type="entry name" value="4-PPantetheinyl_Trfase_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56214">
        <property type="entry name" value="SSF56214"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL73758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="264" mass="29517" checksum="FC6A75A8958EE2F7" modified="2016-01-20" version="1">MGKTGTENKRMYDSPPIIYWTLYEAGDYRSGLVPMTPASFLHPLELQRMEEVRLRLRRDAFLIGRWAAKALLKRTQPAMQHLPLCRVFLGGDVNGLMDLTTDRQTVSGCLAISTSGRQAFCAVTYRDDLPLGASLEHIHPRADSFLVDYFTRLEIQELRGYPAAVQNAWMALGWSVKAAVLTALGTELRVEAREIVVSIPNLLAAKNPMQAWLPVELISAPGGGDGWKVMWQLRGEYIFTIAVWMGKSAIFQPVIKEVTLPEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y206</accession>
    <name>A0A0P6Y206_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_03645</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061607.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78996">
        <property type="protein sequence ID" value="KPL78996"/>
        <property type="gene ID" value="ADN00_03645"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="3"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="251"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="35"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL78996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="489" mass="54167" checksum="5AB451A2ED91676B" modified="2016-01-20" version="1">MKVELRNIHKSFGPVHANNGITLDVPAGTIQGILGENGAGKSTLMKILSGFIREDAGEIVLDGKTVRINTPSDAIKYGIGMLHQDPLDFLPMRVLDNFIIGAEGGVFPNKAQARKEFTDLQAQFHFNIDPDAYVDSLTVGERQQLEILRLLWLGARVLILDEPTTGISSSQREKLFATLQILSEQGKTLFFVSHKLEEVEGLCHRIAVFRQGEVVGEVSPPYNTDDLVRLMFGKEVKLNEREEIARDGTGIQFQNITIEDSRMRISNIDLDIRPGEVIGLAGMAGSGQRQFLKACCGLLKPVAGKVHLHEKDLTGKPYHEFLANGVAYVPASRLEEGLIEGLTLNEHFILAEKQEGFIINRDKYKSITQERIREFNIKGRPGSPVEALSGGNQQRALLALMKTPLDFLLVEHPTRGLDVESSIYIWGKLKERCRQGTSIVFISADLEEILHYSDRVLVFFGGKVSRPLDARSTSVDQLGQLIGGKGFEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y3D3</accession>
    <name>A0A0P6Y3D3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Elongation factor G</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_12365</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-G/EF-2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063323.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12365"/>
    <dbReference type="EnsemblBacteria" id="KPL76126">
        <property type="protein sequence ID" value="KPL76126"/>
        <property type="gene ID" value="ADN00_12365"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01434">
        <property type="entry name" value="EFG_mtEFG1_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03713">
        <property type="entry name" value="EFG_mtEFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035649">
        <property type="entry name" value="EFG_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005517">
        <property type="entry name" value="Transl_elong_EFG/EF2_IV"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03764">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00889">
        <property type="entry name" value="EFG_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="4">
        <location>
            <begin position="7"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL76126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="688" mass="75330" checksum="A690DBED403E0409" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y626</accession>
    <name>A0A0P6Y626_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PABS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_01190</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000003">
        <property type="protein sequence ID" value="KPL80833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061134.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01190"/>
    <dbReference type="EnsemblBacteria" id="KPL80833">
        <property type="protein sequence ID" value="KPL80833"/>
        <property type="gene ID" value="ADN00_01190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006596">
        <property type="term" value="P:polyamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030374">
        <property type="entry name" value="PABS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51006">
        <property type="entry name" value="PABS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 3" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="106"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="149"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="175"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="202"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="PABS" evidence="5">
        <location>
            <begin position="278"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL80833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="518" mass="56987" checksum="B84CEE48AB5111D7" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y6T2</accession>
    <name>A0A0P6Y6T2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_09180</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77296">
        <property type="protein sequence ID" value="KPL77296"/>
        <property type="gene ID" value="ADN00_09180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL77296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="84" mass="9914" checksum="A4FF769D5B7BABA0" modified="2016-01-20" version="1">MFSSLFCWLAAVPAARRQKFSPPLCSIRDQPTLPARQKPSPRRVKPRRVAMCPLRAWLHPSGRRKSLPYRAEEWKPCWCNRVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y7N4</accession>
    <name>A0A0P6Y7N4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_08575</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000022">
        <property type="protein sequence ID" value="KPL77644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77644">
        <property type="protein sequence ID" value="KPL77644"/>
        <property type="gene ID" value="ADN00_08575"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032688">
        <property type="entry name" value="ABC2_membrane_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12679">
        <property type="entry name" value="ABC2_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="62"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="116"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="152"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="184"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="228"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL77644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="256" mass="26488" checksum="B11C4DE3B36844C3" modified="2016-01-20" version="1">MPGEVFIQTLRSTLSSWLKSLLLLCGLLAGLLGWHAAGVPLPVQQVFARLSGASLPLSGWEAWLFAAGFNLLFGLVLCGCAILTGSRLMAGAEERGALALILAFPIPRWQIVVEKALGLAAGILLVCTALRLLAAAPGLFSPRYTLNADALSLAAFTLALPPILLGSLALALASAGGRLGFARWVSLAGWGVWGGLAILSRAVSGMGFLTPVTGIYTANPNGGRPSVWLLLLGTAALLAVMWSAAASGFEQRDLSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y8A5</accession>
    <name>A0A0P6Y8A5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_08495</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062557.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08495"/>
    <dbReference type="EnsemblBacteria" id="KPL77900">
        <property type="protein sequence ID" value="KPL77900"/>
        <property type="gene ID" value="ADN00_08495"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="109" mass="12367" checksum="0325C772ADD165DD" modified="2016-01-20" version="1">MSEQPYMSPDVSSDDRLWAALAYVFSPIIPIVLLLIEDKKNRPFIRAHNMQALIIGIILAIITPIIAAFTFGCGAIIWFVMFFWAYKAYKGEYVNIPVITDLVKNQGWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y913</accession>
    <name>A0A0P6Y913_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_07115</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Responsible for synthesis of pseudouridine from uracil.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a uridine in RNA = a pseudouridine in RNA</text>
            <dbReference type="Rhea" id="RHEA:48348"/>
            <dbReference type="Rhea" id="RHEA-COMP:12068"/>
            <dbReference type="Rhea" id="RHEA-COMP:12069"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pseudouridine synthase RluA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062290.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07115"/>
    <dbReference type="EnsemblBacteria" id="KPL78238">
        <property type="protein sequence ID" value="KPL78238"/>
        <property type="gene ID" value="ADN00_07115"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3241"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120159">
        <property type="term" value="F:rRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd02869">
        <property type="entry name" value="PseudoU_synth_RluA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006225">
        <property type="entry name" value="PsdUridine_synth_RluC/D"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluC/D_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00005">
        <property type="entry name" value="rluA_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S4" evidence="4">
        <location>
            <begin position="20"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR606225-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL78238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="312" mass="34792" checksum="909A1DA9121C2AA8" modified="2016-01-20" version="1">MRPLNNEIEVIFRFDEEESERLDKFLARSHTELSRSRIQALIEGGLVTVDDKVITKTGYALERGQQVNMRVPAPEPSNLIPESIPLDVIFENDDLLVINKPAGMVVHPAAGHSSGTVVHAALAHAPEMEGVGGVQRPGIVHRLDKDTSGLLLIAKNDKAHQWLQSRFKQRSLKKVYLALVDGAPPTPSGRIEAPIGRDPAHRKQMAILPPGKGREAFTEYRTLESFEKHTLLEVNLLTGRTHQIRLHMAFLGCPIVGDGIYGHRKVSLPIRRQFLHAQRLTIQLPGEKSQRTFEAPLPADLQKVLDLLHAER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y9C0</accession>
    <name>A0A0P6Y9C0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Co-chaperonin GroES</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">10 kDa chaperonin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Chaperonin-10</fullName>
            <shortName evidence="3">Cpn10</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">groES</name>
        <name evidence="3" type="synonym">groS</name>
        <name evidence="5" type="ORF">ADN00_07490</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 4">Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the GroES chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062427.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07490"/>
    <dbReference type="EnsemblBacteria" id="KPL78357">
        <property type="protein sequence ID" value="KPL78357"/>
        <property type="gene ID" value="ADN00_07490"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3324"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00320">
        <property type="entry name" value="cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.33.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00580">
        <property type="entry name" value="CH10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020818">
        <property type="entry name" value="Chaperonin_GroES"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037124">
        <property type="entry name" value="Chaperonin_GroES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10772">
        <property type="entry name" value="PTHR10772"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00166">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00297">
        <property type="entry name" value="CHAPERONIN10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00883">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL78357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="88" mass="9659" checksum="530CF14B90C2529B" modified="2016-01-20" version="1">MKIQPLGARVLVKPLDQESKTPSGLLLPDTAKEKPQTGLVVAVGDDEDIKLRENDKVIFAKYSGAEVRLHGVDYLLMECGDILARIVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YA62</accession>
    <name>A0A0P6YA62_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_05570</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061983.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78713">
        <property type="protein sequence ID" value="KPL78713"/>
        <property type="gene ID" value="ADN00_05570"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="118" mass="13101" checksum="0B54AD4DBB029A44" modified="2016-01-20" version="1">MSFEQHQEKSYPKEAQLVYQSALKVTEKLGGKVISSTPEGLRFEARFPKVILGKTLGERTQLSCAVRADGENSQVILDAFPLDALERKLLFGARKGVTLTVVTWFTAHLEHTLGLLSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YAE5</accession>
    <name>A0A0P6YAE5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_06230</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BMP lipoprotein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06230"/>
    <dbReference type="EnsemblBacteria" id="KPL78814">
        <property type="protein sequence ID" value="KPL78814"/>
        <property type="gene ID" value="ADN00_06230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003760">
        <property type="entry name" value="PnrA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02608">
        <property type="entry name" value="Bmp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133481" evidence="3">
        <location>
            <begin position="18"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="Bmp" evidence="4">
        <location>
            <begin position="27"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL78814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="335" mass="35891" checksum="19A13433E226A6C5" modified="2016-01-20" version="1">MLVFLMLAILLVSAAGCAPKAEAPQAEKVVYLINGALGDKSFYDSGKEGIDQIAAEYGVETRTIECNFDAGQYEPSLQAAVNYADVIFVISYGYEDQLKEYADKYPDKIFVNLDTVVQNEKNTITSVDFIEEESAYLTGVVAALTTLDTSIPNVNADKIIGAVGGDVDPVIQAFVFAYTNGAQSIDPDIKVETKYLGSWDDTAKGKQAALQLYDMKADVVFQIAAAAGIGVLQAAGERGLYAIGVDTNQNDIVPGHVVASDIKNVGQAIIDVFKTIKDGTYQPGQVLEYGLATGGVDVDFTAQQQVLPQGTIDQVNAIRQQIIDGTLVVERYTGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YAZ1</accession>
    <name>A0A0P6YAZ1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">A_deaminase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_04255</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061891.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04255"/>
    <dbReference type="EnsemblBacteria" id="KPL79088">
        <property type="protein sequence ID" value="KPL79088"/>
        <property type="gene ID" value="ADN00_04255"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.208"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019239">
        <property type="term" value="F:deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001365">
        <property type="entry name" value="A_deaminase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006330">
        <property type="entry name" value="Ado/ade_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43114">
        <property type="entry name" value="PTHR43114"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00962">
        <property type="entry name" value="A_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01430">
        <property type="entry name" value="aden_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="A_deaminase" evidence="3">
        <location>
            <begin position="11"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL79088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="340" mass="37667" checksum="036FE10F2B1BB169" modified="2016-01-20" version="1">MQIEKFVEMMPKVELHVHLEGSIRPQTLLKLAGRYGVALPASTAAGLQEWFTFRDFDHFIEIYKTISSCIRCADDIELIARDFLAGQAEQNILYSEVTFTADTHFRNGIAFEEQMAALRRANEWAKKDLGIEMRLVLDIPRMISSEDGHYTADWVLQTAGNGLVAALGLGGPEVGYPPERFSDSFRKVLAAGLPSVPHAGETEGPASIWGAVNTLGARRIGHGVRCLEDARLVDVLRERQIPLEVCPTSNVCLKVVDRIEAHPLPRLLAEGLYVTVNSDDPALFNTSLTREFLICAQVFGMPREQLKQLTLNAARATLLPAEEKRALVERVENGFSELGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YBN9</accession>
    <name>A0A0P6YBN9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">PLDc_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_03185</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000014">
        <property type="protein sequence ID" value="KPL79344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061514.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000014.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79344">
        <property type="protein sequence ID" value="KPL79344"/>
        <property type="gene ID" value="ADN00_03185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027379">
        <property type="entry name" value="CLS_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13396">
        <property type="entry name" value="PLDc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="PLDc_N" evidence="7">
        <location>
            <begin position="24"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF13396"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL79344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="68" mass="7880" checksum="7B199B7A5384F3B7" modified="2016-01-20" version="1">MDALNLLQQYLPLLIPVFVVQLGLLIFALVDLLKREKTNGPKWLWVIIIVFVNMIGPIVYFIVGRRDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YC51</accession>
    <name>A0A0P6YC51_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">3-deoxy-7-phosphoheptulonate synthase</fullName>
            <ecNumber evidence="3">2.5.1.54</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_02455</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.54" evidence="3"/>
    <dbReference type="EMBL" id="LGCL01000011">
        <property type="protein sequence ID" value="KPL79564.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061373.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000011.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02455"/>
    <dbReference type="EnsemblBacteria" id="KPL79564">
        <property type="protein sequence ID" value="KPL79564"/>
        <property type="gene ID" value="ADN00_02455"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2801"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003849">
        <property type="term" value="F:3-deoxy-7-phosphoheptulonate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016832">
        <property type="term" value="F:aldehyde-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006218">
        <property type="entry name" value="DAHP1/KDSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041071">
        <property type="entry name" value="DAHP_snth_FXD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006268">
        <property type="entry name" value="DAHP_syn_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18152">
        <property type="entry name" value="DAHP_snth_FXD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00793">
        <property type="entry name" value="DAHP_synth_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01361">
        <property type="entry name" value="DAHP_synth_Bsub"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DAHP_snth_FXD" evidence="2">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="DAHP_synth_1" evidence="1">
        <location>
            <begin position="86"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79564.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="337" mass="36385" checksum="F674775492A8C3E5" modified="2016-01-20" version="1">MIVVMKKGASPMQVEAVIERIELTGCKVHPSVGEETTILGVIGDVRAVNIAQIQLMDGVDRTMRVARPYKLASREFNPTDTLIRVSDVVIGGNKVVVMAGPCAVESREQMLETAHAVKAAGATMLRGGAFKPRSSPYSFQGLGEEGLQYLALAREETGLPFVTEVMEPQMVPLVSQYADMLQIGARNMQNFALLHAVGEAHMPVLLKRGLMSTIEEWLMSAEYILSHGNNQVILCERGIRTFETSTRNTLDISAVPVLKQLTHLPVMVDPSHATGKWDLVEPTARAGVAAGADGLVIEVHPRPEEALSDGPQSLKPERFAALMTSLPAIAAAIGRSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GKM4</accession>
    <name>A0A0N8GKM4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">INTEIN_C_TER domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_18870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064593.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18870"/>
    <dbReference type="EnsemblBacteria" id="KPL70106">
        <property type="protein sequence ID" value="KPL70106"/>
        <property type="gene ID" value="ADN00_18870"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016539">
        <property type="term" value="P:intein-mediated protein splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003586">
        <property type="entry name" value="Hint_dom_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036844">
        <property type="entry name" value="Hint_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030934">
        <property type="entry name" value="Intein_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006141">
        <property type="entry name" value="Intein_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006528">
        <property type="entry name" value="Phage_head_morphogenesis_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04233">
        <property type="entry name" value="Phage_Mu_F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00305">
        <property type="entry name" value="HintC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51294">
        <property type="entry name" value="SSF51294"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50818">
        <property type="entry name" value="INTEIN_C_TER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50817">
        <property type="entry name" value="INTEIN_N_TER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="INTEIN_C_TER" evidence="1">
        <location>
            <begin position="580"/>
            <end position="601"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="883" mass="99477" checksum="8FC58836B1B88134" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GL32</accession>
    <name>A0A0N8GL32_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_16830</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL71370">
        <property type="protein sequence ID" value="KPL71370"/>
        <property type="gene ID" value="ADN00_16830"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006025780" evidence="1">
        <location>
            <begin position="22"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL71370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="261" mass="28593" checksum="2DC33EC93795EC40" modified="2016-01-20" version="1">MKRANLFPVLMLILASLACGALPKQAEGPVEAQEEPTILLPTSEISGVGPSEPTPVVVIEDKSTVKEAYDPFDAATDDWSLPFFVTTKALPGREKSAVELKNGNMTFSLMDEETYLYEFYESMTPEDVLVETKYQAGGNHTVNGVALICRAASDLSAWYEFRLGSDTKYSIFRYDVSRRDEGKNPYILLAKGGSQAISPSKENIVRILCKGSDLVLEVNGQQVSSVQDGTLTGEGLVGVGAMSYNLTPTYMMFDYFSYTQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GLV6</accession>
    <name>A0A0N8GLV6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dihydropteroate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_14560</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000035">
        <property type="protein sequence ID" value="KPL73562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063760.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000035.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14560"/>
    <dbReference type="EnsemblBacteria" id="KPL73562">
        <property type="protein sequence ID" value="KPL73562"/>
        <property type="gene ID" value="ADN00_14560"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2078"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004156">
        <property type="term" value="F:dihydropteroate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009396">
        <property type="term" value="P:folic acid-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00739">
        <property type="entry name" value="DHPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045031">
        <property type="entry name" value="DHP_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006390">
        <property type="entry name" value="DHP_synth_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011005">
        <property type="entry name" value="Dihydropteroate_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000489">
        <property type="entry name" value="Pterin-binding_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20941">
        <property type="entry name" value="PTHR20941"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00809">
        <property type="entry name" value="Pterin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51717">
        <property type="entry name" value="SSF51717"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01496">
        <property type="entry name" value="DHPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00793">
        <property type="entry name" value="DHPS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50972">
        <property type="entry name" value="PTERIN_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pterin-binding" evidence="1">
        <location>
            <begin position="13"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL73562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="294" mass="31829" checksum="E3B6C0D77E68C69F" modified="2016-01-20" version="1">MKAWEEFRWGQQTYVMGILNITADSFSGDGLLKTRDPVRSALERARRFVKAGAHILDVGGESTRPGASQVAEQEELERVIPVIEALAAARLDAVISVDTYKARVAEAALQAGAAWINDVWGLRADPGMAELAARSQAPLVLMHNRSQPADAELQERLGGRYVGSVYTDLIGEVKAELMQSVELARRAGVRDEKIVLDPGIGFGKTVEQNLELLNRLDEIRALGFPILLGPSRKSFIGYTLNLPYNQRVEGTAAAVAVGIARGADMIRVHDVRAMARVARMTDAITRRGAAGSTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GM23</accession>
    <name>A0A0N8GM23_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13915</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063634.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000033.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74098">
        <property type="protein sequence ID" value="KPL74098"/>
        <property type="gene ID" value="ADN00_13915"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="91" mass="9889" checksum="1ECBADEFFD74D7E6" modified="2016-01-20" version="1">MKEEQAAVIAGQLRHALDLMQAEINALQARQSHQAELTHQRLCVLEKRADDQEARLRSASEGVTQFKVWSGLAAGGSGLMSLAALVRAFFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMS4</accession>
    <name>A0A0N8GMS4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DNA mismatch repair protein MutL</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">mutL</name>
        <name evidence="8" type="ORF">ADN00_12255</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">This protein is involved in the repair of mismatches in DNA. It is required for dam-dependent methyl-directed DNA mismatch repair. May act as a 'molecular matchmaker', a protein that promotes the formation of a stable complex between two or more DNA-binding proteins in an ATP-dependent manner without itself being part of a final effector complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the DNA mismatch repair MutL/HexB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063304.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12255"/>
    <dbReference type="EnsemblBacteria" id="KPL76106">
        <property type="protein sequence ID" value="KPL76106"/>
        <property type="gene ID" value="ADN00_12255"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3927"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032300">
        <property type="term" value="C:mismatch repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1540.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00149">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014762">
        <property type="entry name" value="DNA_mismatch_repair_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020667">
        <property type="entry name" value="DNA_mismatch_repair_MutL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002099">
        <property type="entry name" value="DNA_mismatch_repair_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013507">
        <property type="entry name" value="DNA_mismatch_S5_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038973">
        <property type="entry name" value="MutL/Mlh/Pms"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014790">
        <property type="entry name" value="MutL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042120">
        <property type="entry name" value="MutL_C_dimsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042121">
        <property type="entry name" value="MutL_C_regsub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037198">
        <property type="entry name" value="MutL_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10073">
        <property type="entry name" value="PTHR10073"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01119">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08676">
        <property type="entry name" value="MutL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01340">
        <property type="entry name" value="DNA_mis_repair"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00853">
        <property type="entry name" value="MutL_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118116">
        <property type="entry name" value="SSF118116"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00585">
        <property type="entry name" value="mutl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00058">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3 4" id="KW-0234">DNA repair</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_mis_repair" evidence="7">
        <location>
            <begin position="208"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="MutL_C" evidence="6">
        <location>
            <begin position="408"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="364"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL76106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="595" mass="64165" checksum="D7052536CF066341" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMS8</accession>
    <name>A0A0N8GMS8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_12440</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063338.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76138">
        <property type="protein sequence ID" value="KPL76138"/>
        <property type="gene ID" value="ADN00_12440"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="194" mass="21121" checksum="19BE9293462717FA" modified="2016-01-20" version="1">MAAGMIAGAVLFGLSWLPVKTDVQRVVLNPRTLNLPTDLIALLEGRELIVDAPTWLWQGGQSEIRLRTNLGSQTEALNLILEANLAINGGNSLPIGELAMPIQGTDWKELRWQISDDEMESGAVSGTMWVHATFVRPAEQQKARTALLAKPLDIPVRSMIPGLALGPQRWIGVGLFLVAGCSRLALGRRRARLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GN36</accession>
    <name>A0A0N8GN36_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5 family acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10545</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062961.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77002">
        <property type="protein sequence ID" value="KPL77002"/>
        <property type="gene ID" value="ADN00_10545"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="164" mass="18172" checksum="07BCF2E3BF16CBB2" modified="2016-01-20" version="1">MRVIYRLAAPGDQDFLWEMLYQAVYVPPGEPAPGRDILRLPEIARYAENWGQPGDLGLVAAAEDGQPLGAAWLRPLTGANRGYGYVADVYPELCMALLPDFRGQGIGEPLLKHLLDLAKTRWRGVSLSVQRPNPAEKLYRRLGFVALEQHGDSITMLLRFSPSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GN81</accession>
    <name>A0A0N8GN81_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Bac_transf domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_09265</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial sugar transferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09265"/>
    <dbReference type="EnsemblBacteria" id="KPL77362">
        <property type="protein sequence ID" value="KPL77362"/>
        <property type="gene ID" value="ADN00_09265"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003362">
        <property type="entry name" value="Bact_transf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017475">
        <property type="entry name" value="EPS_sugar_tfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017472">
        <property type="entry name" value="Undecaprenyl-P_galact_Ptfrase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02397">
        <property type="entry name" value="Bac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03025">
        <property type="entry name" value="EPS_sugtrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03022">
        <property type="entry name" value="WbaP_sugtrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="83"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="250"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="Bac_transf" evidence="8">
        <location>
            <begin position="248"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL77362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="445" mass="50156" checksum="F6497E20C9B90C19" modified="2016-01-20" version="1">MLTAAALAALLVRRLALGPLDSGLQHWLPPYIAVYLLVYAARRLYPAVGLGLIAEFRSLTLTTTLVTLILASLSFLTRTTSGLSRLIFVLTWFASLAFVPAGRVFTRTLLARLGWWGEPAAIIGPYQQALRAAERYRASPKIGLRPALIFTPLDPSSPPDDDLPVYALRDMHRVPQLAHIHTALILYQSLEELPQLRERYQDTFQRVILIRDGDNGLNLCGMSVREYGGLLSFEIHHNLLDRAAQTEKRLIDLLGSGLGLILISPLLALVALLIKITSPGPVFYRQQRLGKDGRVIQMLKFRTMHVNADQVLKSFLENNPHMREEWDRYQKLRGDPRITPIGGCLRRFSIDELPQLWNVLTGEMSLVGPRPIMLNQAGIYGPTLKHYQRVLPGMTGLWQISGRNQATFSQRATFDHHYVMNWSVWLDIYILAKTVFVVLKHDGAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNE0</accession>
    <name>A0A0N8GNE0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Acetyl-CoA acetyltransferase</fullName>
            <ecNumber evidence="4">2.3.1.9</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_08085</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the thiolase-like superfamily. Thiolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.9" evidence="4"/>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062481.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08085"/>
    <dbReference type="EnsemblBacteria" id="KPL77834">
        <property type="protein sequence ID" value="KPL77834"/>
        <property type="gene ID" value="ADN00_08085"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.617"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003985">
        <property type="term" value="F:acetyl-CoA C-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002155">
        <property type="entry name" value="Thiolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020617">
        <property type="entry name" value="Thiolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020616">
        <property type="entry name" value="Thiolase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02803">
        <property type="entry name" value="Thiolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00108">
        <property type="entry name" value="Thiolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000429">
        <property type="entry name" value="Ac-CoA_Ac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Thiolase_N" evidence="2">
        <location>
            <begin position="7"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="Thiolase_C" evidence="3">
        <location>
            <begin position="260"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL77834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="385" mass="40899" checksum="F1E028005F73B7A3" modified="2016-01-20" version="1">MREVAVIGIGQTKIDEHWDSSLRVLAGDAALAAIHDAGVSGVEAVFVGNMMSGSANHQQHLGAYIADWIGLRYTEAVRVEAACSSGAATFRSAIMAVASGEVDSALAIGVEKMTDSPGAEITAELATAADADWEGEIGISFVALNALVMQRYMYEYQWKHDDFANFSINAHANAVHNPNARFRKAISFSTYQKSPMICEPISVMDASPMGDGAAALVIVPAEMARRINRPVIRVAGSGAATDALAVHDRRDPLWLSAAEKSAKQAYQQAGIGPEQINFFEVHDAFTIMATLSLEACGFAERGQGVRLALENEITPTGRIPIATMGGLKGRGHPVGATGMYQLAETVIQLRGEAGPTQIENARFGMTQNIGGSGSNIITHILQRES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNL1</accession>
    <name>A0A0N8GNL1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_06655</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FGGY kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000018">
        <property type="protein sequence ID" value="KPL78402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06655"/>
    <dbReference type="EnsemblBacteria" id="KPL78402">
        <property type="protein sequence ID" value="KPL78402"/>
        <property type="gene ID" value="ADN00_06655"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000577">
        <property type="entry name" value="Carb_kinase_FGGY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="Carb_kinase_FGGY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018483">
        <property type="entry name" value="Carb_kinase_FGGY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018484">
        <property type="entry name" value="Carb_kinase_FGGY_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02782">
        <property type="entry name" value="FGGY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00370">
        <property type="entry name" value="FGGY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000538">
        <property type="entry name" value="GlpK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00445">
        <property type="entry name" value="FGGY_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FGGY_N" evidence="2">
        <location>
            <begin position="7"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="FGGY_C" evidence="3">
        <location>
            <begin position="289"/>
            <end position="445"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL78402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="507" mass="55250" checksum="57938C54560E456E" modified="2016-01-20" version="1">MKTLSFAIGIDLGIGSCKTVLLDESARILSQASAAYPASDTASRWQEQRPESLLEGLITSVRSAVQTSGLNPANCLGITIGGALHSLTALDKRDQPLMGLLTWADSRAHHQAGQIRQSGRAHDLYLRTGCPSHPLYPFYKILWLRENHPDAFAKATWFLSAKEYVLYRMTGKRIVDYNVAAGSGLLNTLNLGWDKEMLSLAGISPEQLSTVADPREFVGWLKPALATQMGLNPHTPVILGSSDAVNDSLGAGAVSRRQAACMVGVSGAIRCLQTQPALDALERVCCYAVDQKHWLVGGAINNGGLAASWFKDALSNGKADSPSTPDFDDLLAWAAEIPAGSEGVLCLPFFTAERSPYWNTDVRGTFYGLQLGHDQRHLSRALLEGVAFRLRSVLDSLDETIPNLMELRASGGFVQSPIWLQITADVLNRPLHIPAVKETSAMAAAFWVFLNAGVFSSFEDLAKLVPIAKQVEPLAEHQPIYHQQYQRYQELYRALLPVFKPPSTPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNQ2</accession>
    <name>A0A0N8GNQ2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH luxR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_05670</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062000.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78730">
        <property type="protein sequence ID" value="KPL78730"/>
        <property type="gene ID" value="ADN00_05670"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1611"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041617">
        <property type="entry name" value="TPR_MalT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17874">
        <property type="entry name" value="TPR_MalT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="820"/>
            <end position="885"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="887" mass="98746" checksum="C230DAAAAF62A585" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GPJ6</accession>
    <name>A0A0N8GPJ6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_00700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061028.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL81082">
        <property type="protein sequence ID" value="KPL81082"/>
        <property type="gene ID" value="ADN00_00700"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL81082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="136" mass="15448" checksum="2149EB6637EB6794" modified="2016-01-20" version="1">MNRKLFLARVLVSLVLFLNLQAAVFFFIFPQRFVPSFQLSGDTGPFVIQSMGVLFLMWTVPYFFAAINPIKYQVALVQAVIMQIIGVAGESLIYLHLPEKLTILKLSLQRFILFDSAGVLLLITAFLLVRLQNDHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WK23</accession>
    <name>A0A0P6WK23_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_18285</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064490.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70015">
        <property type="protein sequence ID" value="KPL70015"/>
        <property type="gene ID" value="ADN00_18285"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2963"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="257" mass="27424" checksum="9258F3513815170E" modified="2016-01-20" version="1">MADDHFVDFTGKTVLVTGASAGLGRAVAVRFAQYHARVGVHYHTNRSGAEETARLIEALDGECVLLQADLSQESGVQAMFVELKAKAERLDVLINNAGIYPSKPLMEISGEEWDAMMAANLRSVFLCTRQAAEWMQTRGGGAVVNIASIEAFMPARQHAHYCASKAGVLMLTRSAALELGPAGIRVNAVSPGLIHREGIEENWPEGVERWLKACPLGRMGAPEEVADMCLFLASERASWISGANLVADGGMAVTGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WK80</accession>
    <name>A0A0P6WK80_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ERCC4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_18815</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064581.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18815"/>
    <dbReference type="EnsemblBacteria" id="KPL70097">
        <property type="protein sequence ID" value="KPL70097"/>
        <property type="gene ID" value="ADN00_18815"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006259">
        <property type="term" value="P:DNA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006166">
        <property type="entry name" value="ERCC4_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02732">
        <property type="entry name" value="ERCC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00891">
        <property type="entry name" value="ERCC4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ERCC4" evidence="1">
        <location>
            <begin position="5"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00891"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="248" mass="27155" checksum="292BBD48C053A570" modified="2016-01-20" version="1">MSITAVMIDSREPEWVKNLQFNNAPAAVTFLESGDAWVACDDGITLIVERKTPDDFLNSLKQERLMVQIADLAEYRKTHGFWPYLVITDEIIRGTNGKAITNRGETGWNWNAVQGALLTVQEAGVFVQFCAGDADYGPCLARLASRKRDPKMLVMPAREARILGNQAAFIAGLPGIGLEKVQTVMQYCGTPAWALVALTDATSQIPGIGEGIKRGVRWTLGLKESEQIGVVLGENHQEELAILNLGEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WMQ9</accession>
    <name>A0A0P6WMQ9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_17595</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000042">
        <property type="protein sequence ID" value="KPL71213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064362.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000042.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL71213">
        <property type="protein sequence ID" value="KPL71213"/>
        <property type="gene ID" value="ADN00_17595"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL71213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="100" mass="11437" checksum="3AB1BA4098A348F2" modified="2016-01-20" version="1">MAGKLILSWDIARDHEREYFEFVVREFIPGVQRLGLELTDAWATAYGNQPQIMVGAVGNSIEDVRSVLDSNDWLTLSDRLQAYVRNYKEKVVHSTGGFQF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WPQ0</accession>
    <name>A0A0P6WPQ0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ADN00_16310</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064104.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72045">
        <property type="protein sequence ID" value="KPL72045"/>
        <property type="gene ID" value="ADN00_16310"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3700"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="66"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="170"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="258"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="290"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="45"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="347"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="381"/>
            <end position="388"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL72045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="587" mass="66111" checksum="D38F91614336F985" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WSD5</accession>
    <name>A0A0P6WSD5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">S1 motif domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_14910</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000036">
        <property type="protein sequence ID" value="KPL73078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063829.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000036.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14910"/>
    <dbReference type="EnsemblBacteria" id="KPL73078">
        <property type="protein sequence ID" value="KPL73078"/>
        <property type="gene ID" value="ADN00_14910"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1845"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006139">
        <property type="term" value="P:nucleobase-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05685">
        <property type="entry name" value="S1_Tex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.650">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3500.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041692">
        <property type="entry name" value="HHH_9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044146">
        <property type="entry name" value="S1_Tex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023323">
        <property type="entry name" value="Tex-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023319">
        <property type="entry name" value="Tex-like_HTH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018974">
        <property type="entry name" value="Tex-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032639">
        <property type="entry name" value="Tex_YqgF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006641">
        <property type="entry name" value="YqgF/RNaseH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037027">
        <property type="entry name" value="YqgF/RNaseH-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17674">
        <property type="entry name" value="HHH_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09371">
        <property type="entry name" value="Tex_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16921">
        <property type="entry name" value="Tex_YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00732">
        <property type="entry name" value="YqgFc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1 motif" evidence="1">
        <location>
            <begin position="645"/>
            <end position="708"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL73078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="709" mass="78916" checksum="2EECF95B4F3249BF" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WT01</accession>
    <name>A0A0P6WT01_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Hepar_II_III_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_18315</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18315"/>
    <dbReference type="EnsemblBacteria" id="KPL70020">
        <property type="protein sequence ID" value="KPL70020"/>
        <property type="gene ID" value="ADN00_18315"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008929">
        <property type="entry name" value="Chondroitin_lyas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012480">
        <property type="entry name" value="Hepar_II_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031680">
        <property type="entry name" value="Hepar_II_III_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07940">
        <property type="entry name" value="Hepar_II_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16889">
        <property type="entry name" value="Hepar_II_III_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48230">
        <property type="entry name" value="SSF48230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hepar_II_III_N" evidence="1">
        <location>
            <begin position="111"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="651" mass="72349" checksum="1B1565B69314484E" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WT10</accession>
    <name>A0A0P6WT10_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_15435</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase A31 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063929.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15435"/>
    <dbReference type="EnsemblBacteria" id="KPL72215">
        <property type="protein sequence ID" value="KPL72215"/>
        <property type="gene ID" value="ADN00_15435"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008047">
        <property type="term" value="F:enzyme activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023430">
        <property type="entry name" value="Pept_HybD-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000671">
        <property type="entry name" value="Peptidase_A31"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30302">
        <property type="entry name" value="PTHR30302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53163">
        <property type="entry name" value="SSF53163"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00072">
        <property type="entry name" value="hydrog_prot"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="160" mass="18083" checksum="345C1F08ED3ECA02" modified="2016-01-20" version="1">MKPTLIFAYGNFDREDDGVAWHIAKMLAQKYGQDFPDSPEDEVPLPGPYPHIQFDLQLFPELAEELVNYERVVFIDAHTGAVPDDLNIQELSPSFQNSPLTHHMTPQTVLEIAKTLYDAQPQALLVSVRGYQFGFSRELSAQTAELAAQAVMKIEVWLDH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WTI3</accession>
    <name>A0A0P6WTI3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MFS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_14505</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000035">
        <property type="protein sequence ID" value="KPL73553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063750.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000035.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14505"/>
    <dbReference type="EnsemblBacteria" id="KPL73553">
        <property type="protein sequence ID" value="KPL73553"/>
        <property type="gene ID" value="ADN00_14505"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="107"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="170"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="223"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="263"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="315"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="401"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="11"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL73553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="447" mass="48278" checksum="E4D15C0C8F78C23B" modified="2016-01-20" version="1">MKHRIPSTWKTFYILWAGQALSLLGTSMTRFALMIWAFEKEQSVSALALLGFFSTFAFILASPLAGVLVDRWDRRKVMLLADALAGLMTAALFILNLRGELQVWHLYLATGLTGAFSAFQEPAFWATISLIVPEGQFARANGMVGLAKSAVTMLAPIFAGLLLQSAGLNWVMTADLLTMSLALGSLLLIRFPAPPASAEGQQARGSYLQEIRFGARYILQRRGLVEILAVFFFINLFSTLTYFGVHTPLILTRTGGDEVGLGIVRTVMGLGGILGGLLISIWGMPRRKTRVFLITTALSFLVCDFLTAASRSVPAWAIAGFLAELSIPFIVSPYYALWQEIVPPDVQGRVFATREMLQVSSQPVGYLFSGLLADRLFEPALQSSTLLNQWLNPLIGSGPGAGMTAMFLCTALLGCLTGLLGLASPAIRHLDEHPQRASIAGVSGAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WX49</accession>
    <name>A0A0P6WX49_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13535</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063554.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000031.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13535"/>
    <dbReference type="EnsemblBacteria" id="KPL74852">
        <property type="protein sequence ID" value="KPL74852"/>
        <property type="gene ID" value="ADN00_13535"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1200"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01547">
        <property type="entry name" value="SBP_bac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132691" evidence="1">
        <location>
            <begin position="24"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="459" mass="47905" checksum="024FB061EA21100B" modified="2016-01-20" version="1">MARKLYTLLSFVFIAAFMLSACAAPTEAPAAAADAPAAATEAPAAATEAPAAAAEAPAAAAEPVTITWWHISTKDPALSDWQKMADDYMAAHPNVKIEITVLENESFKTKLTTVMQSGEVPDIFQSWGQGGMIEQVNAGLLKDITADLDANGGEWRNSLGALDAFAVDGKNYGVPWDMGAVTFWYNKDLFAQAGIDTVPTTWSEFLATCEKLKAAGITPISVGEGDKWPGMHIWAYLVSRIGGAEAFAAAAATGDARTGSFEDEAFVQAGYELKKLVDGGYFQEGFLGATHDEMNATFGNGKAAMELGGQWSPSVQAANSADLAGVKNLGMFSFPAVEGGAGLVTDIIGGGNGFAIGVNAEPEAIDFVKYLTSVENQKVIAASNTGIPVAKGAGEALTDPNMVMVAEAVANSTYYQLYFDQVLPSAMGGIINDAVQKLFAGVATPEEVCAEIEAGFLSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WYB1</accession>
    <name>A0A0P6WYB1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_17265</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064297.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL71437">
        <property type="protein sequence ID" value="KPL71437"/>
        <property type="gene ID" value="ADN00_17265"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="24"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="170"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL71437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="550" mass="61199" checksum="198137FB4B346B44" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZ20</accession>
    <name>A0A0P6WZ20_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_13100</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000029">
        <property type="protein sequence ID" value="KPL75291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063474.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000029.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13100"/>
    <dbReference type="EnsemblBacteria" id="KPL75291">
        <property type="protein sequence ID" value="KPL75291"/>
        <property type="gene ID" value="ADN00_13100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2898"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0807">Transducer</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="14"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="195"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="5">
        <location>
            <begin position="242"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="4">
        <location>
            <begin position="354"/>
            <end position="590"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL75291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="668" mass="72533" checksum="9871B8F6201FA483" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZB2</accession>
    <name>A0A0P6WZB2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Aamy domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_16570</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72086">
        <property type="protein sequence ID" value="KPL72086"/>
        <property type="gene ID" value="ADN00_16570"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3756"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11356">
        <property type="entry name" value="AmyAc_Sucrose_phosphorylase-like_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033746">
        <property type="entry name" value="GGa_phosphorylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045857">
        <property type="entry name" value="O16G_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016377">
        <property type="entry name" value="Sucrose_GGa_phosphorylase-rel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003059">
        <property type="entry name" value="Sucrose_phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aamy" evidence="2">
        <location>
            <begin position="56"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>sucrose</name>
            <dbReference type="ChEBI" id="CHEBI:17992"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>sucrose</name>
            <dbReference type="ChEBI" id="CHEBI:17992"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="230"/>
            <end position="232"/>
        </location>
        <ligand>
            <name>sucrose</name>
            <dbReference type="ChEBI" id="CHEBI:17992"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="343"/>
            <end position="344"/>
        </location>
        <ligand>
            <name>sucrose</name>
            <dbReference type="ChEBI" id="CHEBI:17992"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="450"/>
        </location>
        <ligand>
            <name>sucrose</name>
            <dbReference type="ChEBI" id="CHEBI:17992"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR003059-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL72086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="583" mass="66284" checksum="7B5C2D7B59932E12" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZE0</accession>
    <name>A0A0P6WZE0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">Superoxide dismutase</fullName>
            <ecNumber evidence="2 6">1.15.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_15170</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Destroys radicals which are normally produced within the cells and which are toxic to biological systems.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>2 H(+) + 2 superoxide = H2O2 + O2</text>
            <dbReference type="Rhea" id="RHEA:20696"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16240"/>
            <dbReference type="ChEBI" id="CHEBI:18421"/>
            <dbReference type="EC" id="1.15.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the iron/manganese superoxide dismutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.15.1.1" evidence="2 6"/>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063882.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15170"/>
    <dbReference type="EnsemblBacteria" id="KPL72172">
        <property type="protein sequence ID" value="KPL72172"/>
        <property type="gene ID" value="ADN00_15170"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.736"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004784">
        <property type="term" value="F:superoxide dismutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.55.40.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001189">
        <property type="entry name" value="Mn/Fe_SOD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019833">
        <property type="entry name" value="Mn/Fe_SOD_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019832">
        <property type="entry name" value="Mn/Fe_SOD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019831">
        <property type="entry name" value="Mn/Fe_SOD_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036324">
        <property type="entry name" value="Mn/Fe_SOD_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036314">
        <property type="entry name" value="SOD_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02777">
        <property type="entry name" value="Sod_Fe_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00081">
        <property type="entry name" value="Sod_Fe_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000349">
        <property type="entry name" value="SODismutase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01703">
        <property type="entry name" value="MNSODISMTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46609">
        <property type="entry name" value="SSF46609"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54719">
        <property type="entry name" value="SSF54719"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00088">
        <property type="entry name" value="SOD_MN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sod_Fe_N" evidence="7">
        <location>
            <begin position="2"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="Sod_Fe_C" evidence="8">
        <location>
            <begin position="96"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="26"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000349-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000414"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL72172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="201" mass="23475" checksum="10EE4ADC61C44858" modified="2016-01-20" version="1">MFQLPELPYKFDALEPYIDAATVEIHYTKHHAAYLKNLNTALEAHPQFFNKSIQEILTDLNQIPAEIRTTVRNNGGGYLNHMIYWEIMGPSCGGEPKGSIAEGIQRFFGSFENFKTLFEKEGMTRFGSGWAWLSKKQDGSLILHSTPNQDSPYSEGLYPVMGVDVWEHAYYLKYQNRRAEYLSNWWNLLNWEEIERRYLHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X117</accession>
    <name>A0A0P6X117_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CpXC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_11660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063192.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11660"/>
    <dbReference type="EnsemblBacteria" id="KPL76013">
        <property type="protein sequence ID" value="KPL76013"/>
        <property type="gene ID" value="ADN00_11660"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025682">
        <property type="entry name" value="CpXC_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14353">
        <property type="entry name" value="CpXC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CpXC" evidence="1">
        <location>
            <begin position="6"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="449" mass="50584" checksum="078FA03D88F130B3" modified="2016-01-20" version="1">MAKTSVACPRCRQPVIADIEQLFDMGTDSQAKQKLLSGMFNVIQCPSCGYAGQTPRPLVYHDPQKELLLTYFPPELGLPVNEQERLIGPLINQVVNNLPLEKRKAYLLRPQSMFTFETLIEKVLEADGVTKEMLDNQQKRLSLIQRLLNLAPEARAEVIKQEENLIDNELFSLLGRVFEIAIAQGDQQGAQAIALLQKDLIEQTAFGQQVKQQNDDAEAAIQALQQASKDGLTHEKLLDIFIAAKSDVSLSTLVSMARPGMDYTFFELLTNRIDAASGEEKQRLTALREKLLSLTERVDKVVQERLAQAKEALEQVLNSGDLEKTILENTDAIDDFFMEALRSELHQAQTDGNIERSAKLKKLVEIIQKLSQPPAEYALVEELLSAEDQTQRQQIMETNSQSINADFLQILNGLVMQSEKESQPAEVQQELKDIYRMALRFSMQNNLTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X196</accession>
    <name>A0A0P6X196_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Molybdenum cofactor biosynthesis protein MoeB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_12400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063330.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12400"/>
    <dbReference type="EnsemblBacteria" id="KPL76132">
        <property type="protein sequence ID" value="KPL76132"/>
        <property type="gene ID" value="ADN00_12400"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3961"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008641">
        <property type="term" value="F:ubiquitin-like modifier activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="PTHR10953"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="SSF69572"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Rhodanese" evidence="4">
        <location>
            <begin position="293"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL76132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="383" mass="41787" checksum="015BD86258658F07" modified="2016-01-20" version="1">MLPDLSSEEVLRYSRHLSLPGVGLQGQRKLKNASVLIVGVGGLGSPAALYLAAAGVGRIGLIDYDWVSYSNLQRQILFDQSQVGKLKVEQARARLLGLNGDIEVIAHPEVFSSKNALELSRQYDILLDGSDNFATRYLANDVCVLQGKPYVYGAVYRFDGQVGVFDARQGACYRCLFPEPPAPGTTPSCAEGGVLGVLPGLIGTLQALETVKLITGAGTPAVNRLLMVDGLTFRFDLIDLRKNPACKICGAQPEIRELMDTASFCGEPLPKIDASINDSWEISPAQLAEEIKNGRPIRLIDVRTPEEVEIAVLAGSQLVPHDQIAHHLDDWGRDEDLVLYCRGGVRSLWALRILREAGFEKARHLAGGILAWAREIDPTMKEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X1E6</accession>
    <name>A0A0P6X1E6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Probable nicotinate-nucleotide adenylyltransferase</fullName>
            <ecNumber evidence="6">2.7.7.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Deamido-NAD(+) diphosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Deamido-NAD(+) pyrophosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Nicotinate mononucleotide adenylyltransferase</fullName>
            <shortName evidence="6">NaMN adenylyltransferase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">nadD</name>
        <name evidence="8" type="ORF">ADN00_11610</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 6">Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>ATP + H(+) + nicotinate beta-D-ribonucleotide = deamido-NAD(+) + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:22860"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57502"/>
            <dbReference type="ChEBI" id="CHEBI:58437"/>
            <dbReference type="EC" id="2.7.7.18"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 6">Cofactor biosynthesis; NAD(+) biosynthesis; deamido-NAD(+) from nicotinate D-ribonucleotide: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the NadD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.18" evidence="6"/>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11610"/>
    <dbReference type="EnsemblBacteria" id="KPL76168">
        <property type="protein sequence ID" value="KPL76168"/>
        <property type="gene ID" value="ADN00_11610"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3797"/>
    <dbReference type="UniPathway" id="UPA00253">
        <property type="reaction ID" value="UER00332"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004515">
        <property type="term" value="F:nicotinate-nucleotide adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009435">
        <property type="term" value="P:NAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02165">
        <property type="entry name" value="NMNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00244">
        <property type="entry name" value="NaMN_adenylyltr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005248">
        <property type="entry name" value="NadD/NMNAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00482">
        <property type="entry name" value="TIGR00482"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0520">NAD</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4 6" id="KW-0662">Pyridine nucleotide biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CTP_transf_like" evidence="7">
        <location>
            <begin position="6"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002324"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL76168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="203" mass="23061" checksum="7C7B4855F06E99FE" modified="2016-01-20" version="1">MGRLGIFGGTFDPPHLGHLILAEECHFQLELDRLLWVVTADPPHKIGQVFSPVEMRVKLAQAAVEEEAAFEISLVDIQRPGPHYAVDTIRLTRQAYPAYSVGYIMGGDSLHNLPTWYHPQEIVQACDFIGVMRRPGDDINLPELEAILPGLSAKVEFVRAPLLEISSREIRERIRAGQPFRHYLPSKVYELIMREGWYHPRGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X2Y6</accession>
    <name>A0A0P6X2Y6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_14470</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000034">
        <property type="protein sequence ID" value="KPL73763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063738.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000034.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL73763">
        <property type="protein sequence ID" value="KPL73763"/>
        <property type="gene ID" value="ADN00_14470"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="231"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL73763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="260" mass="28951" checksum="0512C974F2673B6A" modified="2016-01-20" version="1">MKEFFGVLKYEFGMATRRWGVMAIFGALGLFYLWAFMQPMPDDPVWSEMTNPELWKLAGQMAFSINVFVPVVAGIAIADRMARDVRLGFEELLRSTQLRRWPYVLGKYAGALLSVALPALLINTLISLGCVIRGCSPVMLVYSLPAFVLVTLPGLAFLSAFSLACPMVMPVRVYQVLFTGYWYWGNFLSPKVMPTLTETLLNAAGGYALEGFFSSGYIFLHEHLAHTAQEAVLNIAILLLCGAAALITLERYLAWKARRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X313</accession>
    <name>A0A0P6X313_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_14075</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063664.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000033.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74125">
        <property type="protein sequence ID" value="KPL74125"/>
        <property type="gene ID" value="ADN00_14075"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="140"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="164"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="217"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="259"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="293"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="334"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="369"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="396"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="670"/>
            <end position="692"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL74125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="692" mass="79019" checksum="417F54A2B727D1E9" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X349</accession>
    <name>A0A0P6X349_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_12945</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063439.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000027.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12945"/>
    <dbReference type="EnsemblBacteria" id="KPL75543">
        <property type="protein sequence ID" value="KPL75543"/>
        <property type="gene ID" value="ADN00_12945"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1285"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004107">
        <property type="entry name" value="Integrase_SAM-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13495">
        <property type="entry name" value="Phage_int_SAM_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="5">
        <location>
            <begin position="1"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="4">
        <location>
            <begin position="108"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL75543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="300" mass="33885" checksum="DA23CBBD141CA42A" modified="2016-01-20" version="1">MPHVYEPFREYLIQLGRSERTIAGYLIDINTFACWFEQTNGYSLTPDNLTPTDVREYRQFLLNVRKAKASTINRHLAVLRAYGLWAKTCSGIPYNPVEGIKSIAQQKHAPKWLDRREQAAVLREAERHVQTARTEPAKRQAIRDHCILVTLLNTGLRVSELIDLELSDITMTDRKGELLVRAGKGTKQRVIPLNNTARKALKAWLDVRPESTLQKVFTTQRGAITSRAVQTLLADIGERARIQKMTPHMARHTFAKNLVNSGVTLEKVAMLLGHTSLDTTMVYTTPGMSDLDQAVRVLDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X3V1</accession>
    <name>A0A0P6X3V1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Alanine racemase</fullName>
            <ecNumber evidence="3">5.1.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_11700</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>L-alanine = D-alanine</text>
            <dbReference type="Rhea" id="RHEA:20249"/>
            <dbReference type="ChEBI" id="CHEBI:57416"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="EC" id="5.1.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 3 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; D-alanine biosynthesis; D-alanine from L-alanine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the alanine racemase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.1.1" evidence="3"/>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063199.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11700"/>
    <dbReference type="EnsemblBacteria" id="KPL76019">
        <property type="protein sequence ID" value="KPL76019"/>
        <property type="gene ID" value="ADN00_11700"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3815"/>
    <dbReference type="UniPathway" id="UPA00042">
        <property type="reaction ID" value="UER00497"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008784">
        <property type="term" value="F:alanine racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030632">
        <property type="term" value="P:D-alanine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01201">
        <property type="entry name" value="Ala_racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000821">
        <property type="entry name" value="Ala_racemase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009006">
        <property type="entry name" value="Ala_racemase/Decarboxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011079">
        <property type="entry name" value="Ala_racemase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020622">
        <property type="entry name" value="Ala_racemase_pyridoxalP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00842">
        <property type="entry name" value="Ala_racemase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00992">
        <property type="entry name" value="ALARACEMASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM01005">
        <property type="entry name" value="Ala_racemase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50621">
        <property type="entry name" value="SSF50621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00492">
        <property type="entry name" value="alr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00395">
        <property type="entry name" value="ALANINE_RACEMASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3 4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ala_racemase_C" evidence="6">
        <location>
            <begin position="247"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; specific for D-alanine" evidence="3">
        <location>
            <position position="41"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; specific for L-alanine" evidence="3">
        <location>
            <position position="268"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3 5">
        <location>
            <position position="314"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="3 4">
        <location>
            <position position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR600821-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR600821-52"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL76019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="377" mass="41071" checksum="9B7BD0CC4874C0EF" modified="2016-01-20" version="1">MKKPDGIENFSAWLEIDLGAIRNNVKRLGEIAGKPVMAVVKANGYGHGIVETARAAEAGGAAWCGVARVEEAQILRAAGLQIPILVMGYTPPEQVLPAVEEKISLTVYDPAVAKQYLQTAAASRKRVAVHVKFDSGMGRLGLFPEEGAAFVRWLRQQPEFEVEGIFSHFARADEPLAETTAWQIERMNRLLDQLEKEGLRPALVHVSNSAGTLYHPAGRFDMVRAGIAIYGLHPSDEAPLPDGFKPALSLKARLVSIKELPAQHGVGYNYRYVTSAPERVGVVSIGYADGYRRKKGGQMLVCGQRVTVLGTVCMDQCMVTLQDVPNARVGDEVVLIGAQGSDCITMEEVAQDWGTVNYEVATSMAHRLPRVYFGLQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X4I8</accession>
    <name>A0A0P6X4I8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CMP/dCMP-type deaminase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_11160</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063093.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11160"/>
    <dbReference type="EnsemblBacteria" id="KPL76521">
        <property type="protein sequence ID" value="KPL76521"/>
        <property type="gene ID" value="ADN00_11160"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.928"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016192">
        <property type="entry name" value="APOBEC/CMP_deaminase_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00903">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="3">
        <location>
            <begin position="5"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL76521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="155" mass="16511" checksum="C79B6A75DCCE7877" modified="2016-01-20" version="1">MPLTPQDLTCLREAIALAAAARAHGNHPFGALLALNGDILARAENTVITGADVTQHAELNLVRLAQQQIPPDVLAQATLYTSTEPCPMCSGAIYWAGIPRVVYACSEEALYDLSGGGLALPCREVFARGARPVKVLGPLLEEEAIQPHLGFWQAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X4J3</accession>
    <name>A0A0P6X4J3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">GGDEF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_11290</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063118.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76540">
        <property type="protein sequence ID" value="KPL76540"/>
        <property type="gene ID" value="ADN00_11290"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.956"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="25"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="52"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="80"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="115"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="159"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="3">
        <location>
            <begin position="432"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="187"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL76540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="584" mass="65557" checksum="2B19F89212A4E03C" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X4K7</accession>
    <name>A0A0P6X4K7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FecR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_13450</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063538.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000031.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13450"/>
    <dbReference type="EnsemblBacteria" id="KPL74838">
        <property type="protein sequence ID" value="KPL74838"/>
        <property type="gene ID" value="ADN00_13450"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006860">
        <property type="entry name" value="FecR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04773">
        <property type="entry name" value="FecR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FecR" evidence="2">
        <location>
            <begin position="69"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="252"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL74838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="386" mass="42199" checksum="A95C8324677D0595" modified="2016-01-20" version="1">MQSKRLAAMILATLIVLLFVLSACSSPAVEASSRQMVALTRSGQPEILRNGEANWQILEHKTIIQPGDIIRTGEDTWVYLEINDGSLVGITPNTQASLVTFSTSLQDPITLFDLADGLIYVRVTKELGGGSFKVHTPVMTGSIVGSKMAVQYISSLNTADITCFEGNVNAEIDYNPQESPLSCHLISGVKISTSTKDEWTVKKCQNPAPVQRYELDAYSDWEEMYIDLEFMRQTEAARNQTLTKVARYTKTPTPTEAVEPNQTPLPSSTPTITATPAPVLRPTITVDPDAPLSSAEQANSGTHNYTYTASYSGNCSGPASGEINQMQIRFEGNQVILASGNQQSQFAKVDENTYQASDGVDIVTMTFTEDGFTGESQCVFWTYTRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5B7</accession>
    <name>A0A0P6X5B7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_18805</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064579.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70095">
        <property type="protein sequence ID" value="KPL70095"/>
        <property type="gene ID" value="ADN00_18805"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="252" mass="27812" checksum="24D62C4C66BB6CC8" modified="2016-01-20" version="1">MTFPNNQTVTQPDPWDIADNPPVNHGEYWGQVEIALWYCVLQKGVGKVPFDPQQHSVDQRRTSVEIKIFPIPEQNVSFDIKRDLIAESREWAGIVLKSIKALGLTAKEINGRYVRVKLASTGQTYTNGNGEDRERTTFEFVKAFASEAECKADFLSGGAAPVNTQPQATAHNSAQGTNGNGHNNGNSNGNQEKQTALNFLRIYVQNAARGQTDLNVIRSSLAANISTQPLLAKYFTVDSPETMQLLAEEMTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5J9</accession>
    <name>A0A0P6X5J9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_13075</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000028">
        <property type="protein sequence ID" value="KPL75313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063467.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000028.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13075"/>
    <dbReference type="EnsemblBacteria" id="KPL75313">
        <property type="protein sequence ID" value="KPL75313"/>
        <property type="gene ID" value="ADN00_13075"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL75313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="243" mass="27248" checksum="4B85658486099323" modified="2016-01-20" version="1">MDKGIGFSRTITLDWLDVTASLCIQNIEPLTIRQRLAETISGTVTGIDAQRKTIDVLSAIWVKTEKTAPSIRQEALALFPTLSTSEERLWLHYGMTLVCYPIFRKVVAAIGQISRAEEIITRKMIKDRIAGEYGHLGALDRSVERIIASLTNWGALANTDQVKKYRIVSHHFSAAEELQSWLLTCALTAHPSEAIPFDDLVHLPELYPFKINIGVDTLRRDARFEVQRQGGGLEMVTTNCRAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5T7</accession>
    <name>A0A0P6X5T7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_12720</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75505.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063396.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000027.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL75505">
        <property type="protein sequence ID" value="KPL75505"/>
        <property type="gene ID" value="ADN00_12720"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL75505.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="156" mass="17234" checksum="3466A46FA39A15B4" modified="2016-01-20" version="1">MSEAEQETIPLSEREIAVMVRQLSGGVDPNDVASDLCVAKNMPWREAEAVVARVQAEHGHHIRRWNKTSLTVIGAGIVVGGGLLSFVPALNIFRIIRYAVRTGQFSLRPIFQGDDLSYLSVAMPLQLQPYFLFIGMAMIMGGLVGIYFALREESLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5X8</accession>
    <name>A0A0P6X5X8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Xylose isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09505</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062753.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77344">
        <property type="protein sequence ID" value="KPL77344"/>
        <property type="gene ID" value="ADN00_09505"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4140"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="1">
        <location>
            <begin position="20"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="325" mass="36682" checksum="C9F3A1A67274ECF7" modified="2016-01-20" version="1">MKVGFCTINYSELPLFEVVEMVAKKGYEAVEIPAYTDNGQMDVDEMLRGGNAKKLKKQVEDAGLIISGISNHADSPLVLGPHGKDLASICNGTPAEQVQFGTESMLKCARLANALEVPAVVAFSGIGNFGRFNDWPYPDGWREEEEAFVQNWVPIFDKYAEYGIKVAFEPHPNNIIYDIHTTKRCLSLCDYHPSFAINFDPANILYTGINLGSYIDEIGDRIVLVHAKDCEIVEHNLMRGGYWMLQRDWGTIDRSFRFRIPGWGSINWKSVISELFITGYTGVFSYEHEDVIMSRADGLDKAIAFLKPLMIDQPYEGRKDKLFQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X6F5</accession>
    <name>A0A0P6X6F5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chemotaxis protein CheY</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_05145</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061903.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78646">
        <property type="protein sequence ID" value="KPL78646"/>
        <property type="gene ID" value="ADN00_05145"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1501"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="7"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="140" mass="15872" checksum="3E9DF4774751C407" modified="2016-01-20" version="1">MKDDVRPILLVEDNPMDVDLALRAFRRRKAANDIPVARDGEEAIDLLEEWKNGKTLPIVILLDINLPKISGLEVLKTYKANPITQRIPVVMLTTSKEDKDVAEAYQLGANSYIVKPVDFSKFMEIAEQIELYWAVLNFTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X6Y3</accession>
    <name>A0A0P6X6Y3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PadR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_06260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78820">
        <property type="protein sequence ID" value="KPL78820"/>
        <property type="gene ID" value="ADN00_06260"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005149">
        <property type="entry name" value="Tscrpt_reg_PadR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03551">
        <property type="entry name" value="PadR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PadR" evidence="1">
        <location>
            <begin position="23"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="118" mass="13680" checksum="895E8486C854B88E" modified="2016-01-20" version="1">MESEGRGRGRHSPLAVSLLEPALLVLLNDQARHGYPLLADLEKMGMGTIHPSVVYRTLRDMEELEWIQSTWDGDETQGPPRRVYRLTERGEEVLKHWREEMKSIRELLSELISRTDNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7E0</accession>
    <name>A0A0P6X7E0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glutamine synthetase</fullName>
            <ecNumber evidence="4">6.3.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_03475</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>ATP + L-glutamate + NH4(+) = ADP + H(+) + L-glutamine + phosphate</text>
            <dbReference type="Rhea" id="RHEA:16169"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.1.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the glutamine synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.1.2" evidence="4"/>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061574.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03475"/>
    <dbReference type="EnsemblBacteria" id="KPL78966">
        <property type="protein sequence ID" value="KPL78966"/>
        <property type="gene ID" value="ADN00_03475"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.45"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004356">
        <property type="term" value="F:glutamate-ammonia ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006542">
        <property type="term" value="P:glutamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008147">
        <property type="entry name" value="Gln_synt_b-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036651">
        <property type="entry name" value="Gln_synt_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008146">
        <property type="entry name" value="Gln_synth_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027303">
        <property type="entry name" value="Gln_synth_gly_rich_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004809">
        <property type="entry name" value="Gln_synth_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027302">
        <property type="entry name" value="Gln_synth_N_conserv_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00120">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03951">
        <property type="entry name" value="Gln-synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01230">
        <property type="entry name" value="Gln-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54368">
        <property type="entry name" value="SSF54368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00653">
        <property type="entry name" value="GlnA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00180">
        <property type="entry name" value="GLNA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00181">
        <property type="entry name" value="GLNA_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gln-synt_C" evidence="5">
        <location>
            <begin position="102"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-AMP-tyrosine" evidence="2">
        <location>
            <position position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR604809-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU004356"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL78966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="444" mass="49802" checksum="9ABD84EFD879631E" modified="2016-01-20" version="1">MDAKELLAKVKEDNVKFISYQFTDIFGTVKSVDAPVNQLAGALENGVWFDGSSVEGFARIEESDMHLIIDPNTYAVLPWTPSDLRRARVFCDIHQPDGSPFARDARGVLKRMLKKLDERGWVYNVGPEPEFFLFKQNGGNIHPEPHDVGGYFDFSAHDDAAQVRAELMAALESMGLEVEFGHHEVALGQHEIDFRFADALKTADNVLTLKSTVKAIAAQHGLIASFMPKPIFGINGSGMHCHQSMFDNKGNNLFFKADDEFHLSDLARSFIAGQLAHARAFSAIVAPTVNSYKRLVPGYEAPVYIGWAQRNRSALIRIPRYTPGQDKAVRAELRCPDPSMNPYLAFAVMLATGLDGVDKKMTPPQPLNNVNIYELTPAELAEKNIDQMPGSLREALDEIEKDEVIKAALGEEMFESYKRVKEAEYEDYRIKVSDWELERYLELI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7R9</accession>
    <name>A0A0P6X7R9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="4">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">ADN00_04155</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>ATP + L-seryl-[protein] = ADP + H(+) + O-phospho-L-seryl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + L-threonyl-[protein] = ADP + H(+) + O-phospho-L-threonyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the protein kinase superfamily. RIO-type Ser/Thr kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="4"/>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061700.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04155"/>
    <dbReference type="EnsemblBacteria" id="KPL79076">
        <property type="protein sequence ID" value="KPL79076"/>
        <property type="gene ID" value="ADN00_04155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000687">
        <property type="entry name" value="RIO_kinase"/>
    </dbReference>
    <dbReference type="SMART" id="SM00090">
        <property type="entry name" value="RIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="85"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="29"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001433"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KPL79076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="344" mass="39878" checksum="FD0962722AD4C809" modified="2016-01-20" version="1">MKIKNNQSLNEWINDEDWEEELFPLRKQPAAKNRLTARPQQTQTPPAGAAEDHEDHFDFSYHASRHERQWIEDSLGRFYQQHWIDDVSRLLKGGKEASVYLCQGNPTAPAEQMAAKVYRPRKFRNLKNDWVYRENRANRDSSGNIITDDGLLHAMRKKTSLGMQLLHGAWIEHEYQTLLRLQNAGVNAPAVYARGDNAILMEYFGDGVLPAPTLNEIDLDPAETRRVFERVFQNIERMLELNIIHGDLSAYNILYWDGDIRLIDFPQAISPHENHNAWPIFSRDVARVCEYFSEQGLSGLNPAQLARDLWRSRRLSTVPALDPQYLDADNPEDRARWQSARDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X871</accession>
    <name>A0A0P6X871_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DinB_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063060.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76493">
        <property type="protein sequence ID" value="KPL76493"/>
        <property type="gene ID" value="ADN00_10990"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.892"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024775">
        <property type="entry name" value="DinB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12867">
        <property type="entry name" value="DinB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DinB_2" evidence="1">
        <location>
            <begin position="82"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12867"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="290" mass="32415" checksum="545BF4B4D67518E6" modified="2016-01-20" version="1">MLILTESDLAQTIESFSLLAQNLLDSDLDRPWAWKGYNEGARFIFFRVYEEIRALQARLAAQRRAAGPALTAAQDLLANHHQAYWALQAVLLPGSPRLLDLQPSAGEWTPRQTLRHLINAEFSFFEAIRANLQIHHHGQDPSLNQVQEILETSRAQVEPQHQQAFALSLDSILALYSDIHYHGIESLAGLSDAQLTLPTFDWEEEAFPLEFRLVRLDAHLRQHTIQLQKTLTAHNARPTEAQRLLAHIFSAVAGLESTLLGAPGLNPIALEEAAGQISFYTEALAQVLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X889</accession>
    <name>A0A0P6X889_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_05060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061866.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05060"/>
    <dbReference type="EnsemblBacteria" id="KPL79213">
        <property type="protein sequence ID" value="KPL79213"/>
        <property type="gene ID" value="ADN00_05060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1660.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009923">
        <property type="entry name" value="Dodecin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025543">
        <property type="entry name" value="Dodecin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036694">
        <property type="entry name" value="Dodecin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39324">
        <property type="entry name" value="PTHR39324"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07311">
        <property type="entry name" value="Dodecin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89807">
        <property type="entry name" value="SSF89807"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="68" mass="7687" checksum="EA4F43E7F8BCEA1C" modified="2016-01-20" version="1">MMAHVYKKIELVGTSKVSIQDAIEQAVAKAAQTVKNMRWFEVVETRGEIEDGKVAYWQVTVKIGFTVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X8B7</accession>
    <name>A0A0P6X8B7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NADH-quinone oxidoreductase subunit B</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_04290</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I 20 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04290"/>
    <dbReference type="EnsemblBacteria" id="KPL79240">
        <property type="protein sequence ID" value="KPL79240"/>
        <property type="gene ID" value="ADN00_04290"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006137">
        <property type="entry name" value="NADH_UbQ_OxRdtase-like_20kDa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006138">
        <property type="entry name" value="NADH_UQ_OxRdtase_20Kd_su"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01058">
        <property type="entry name" value="Oxidored_q6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01957">
        <property type="entry name" value="nuoB_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01150">
        <property type="entry name" value="COMPLEX1_20K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0520">NAD</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidored_q6" evidence="2">
        <location>
            <begin position="23"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU004464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="164" mass="17921" checksum="A3E3D3CAC206B855" modified="2016-01-20" version="1">MERIKTWARVNSPWAIHYNSGSCNGCDIELLTTITPHYDLERFGVKLQGSPRHADILLVTGAVSLQSRDRLLRIYNQMPEPKFVVAIGACAVSGGVFRGCYNVLSGVDKLLPVDAFIPGCPPRPEAIIYGVVQLLKNINNPNGSHPAQPLIIEDVPAEEEPYAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X8C2</accession>
    <name>A0A0P6X8C2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N_BRCA1_IG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_11285</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063117.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11285"/>
    <dbReference type="EnsemblBacteria" id="KPL76539">
        <property type="protein sequence ID" value="KPL76539"/>
        <property type="gene ID" value="ADN00_11285"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14947">
        <property type="entry name" value="NBR1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032350">
        <property type="entry name" value="N_BRCA1_central"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16158">
        <property type="entry name" value="N_BRCA1_IG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132900" description="N_BRCA1_IG domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="N_BRCA1_IG" evidence="3">
        <location>
            <begin position="107"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL76539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="315" mass="33222" checksum="A883691C4D72DBCA" modified="2016-01-20" version="1">MNKLRAYLLMVIAGSMLLAGCNLPTRNQTETPAGSEAVQTAAALTVAAYATQVAGTPVAATPTVAPAATQQPTTPPPTQAPTVPPLPTSKPSEVVPCDRGDFGADVTIPDDTVMDPGEKFTKTWRIKNTGSCTWSTSYEAVFVDGNAMNAPVSVKLPKSVAPGETVDISVEMTAPMEPKTYRGNWKLRNASSAVFGLGSKGDQTFYVQIVVKSPGFAVTSATAKVDSAKFEGACPHTFKLSADIKASAAGTVTYFWEFSDGSKSDVVSLKFDEAGTKAVSFDKEFNASGTYSGKIYVDNPNHQYFPAASFELVCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X8E0</accession>
    <name>A0A0P6X8E0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_11410</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76557.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063141.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76557">
        <property type="protein sequence ID" value="KPL76557"/>
        <property type="gene ID" value="ADN00_11410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="211"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="285"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="324"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="355"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="381"/>
            <end position="402"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76557.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="661" mass="74319" checksum="C91785F0F494BCB4" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X8Z9</accession>
    <name>A0A0P6X8Z9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_11760</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063210.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11760"/>
    <dbReference type="EnsemblBacteria" id="KPL76030">
        <property type="protein sequence ID" value="KPL76030"/>
        <property type="gene ID" value="ADN00_11760"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008279">
        <property type="entry name" value="PEP-util_enz_mobile_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036637">
        <property type="entry name" value="Phosphohistidine_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002192">
        <property type="entry name" value="PPDK_AMP/ATP-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00391">
        <property type="entry name" value="PEP-utilizers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01326">
        <property type="entry name" value="PPDK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52009">
        <property type="entry name" value="SSF52009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPDK_N" evidence="2">
        <location>
            <begin position="59"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers" evidence="1">
        <location>
            <begin position="705"/>
            <end position="775"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL76030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="792" mass="90518" checksum="8619D74778B17177" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9J1</accession>
    <name>A0A0P6X9J1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Bifunctional purine biosynthesis protein PurH</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="8">Phosphoribosylaminoimidazolecarboxamide formyltransferase</fullName>
                <ecNumber evidence="8">2.1.2.3</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="8">AICAR transformylase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="8">IMP cyclohydrolase</fullName>
                <ecNumber evidence="8">3.5.4.10</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="8">ATIC</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="8">IMP synthase</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="8">Inosinicase</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="8 10" type="primary">purH</name>
        <name evidence="10" type="ORF">ADN00_05750</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(6S)-10-formyltetrahydrofolate + 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide = (6S)-5,6,7,8-tetrahydrofolate + 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:22192"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:58467"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="EC" id="2.1.2.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>H2O + IMP = 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:18445"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:58467"/>
            <dbReference type="EC" id="3.5.4.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Purine metabolism; IMP biosynthesis via de novo pathway; 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide from 5-amino-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide (10-formyl THF route): step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 8">Purine metabolism; IMP biosynthesis via de novo pathway; IMP from 5-formamido-1-(5-phospho-D-ribosyl)imidazole-4-carboxamide: step 1/1.</text>
    </comment>
    <comment type="domain">
        <text evidence="8">The IMP cyclohydrolase activity resides in the N-terminal region.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the PurH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.3" evidence="8"/>
    <dbReference type="EC" id="3.5.4.10" evidence="8"/>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062014.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05750"/>
    <dbReference type="EnsemblBacteria" id="KPL78743">
        <property type="protein sequence ID" value="KPL78743"/>
        <property type="gene ID" value="ADN00_05750"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1626"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00133"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003937">
        <property type="term" value="F:IMP cyclohydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004643">
        <property type="term" value="F:phosphoribosylaminoimidazolecarboxamide formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00139">
        <property type="entry name" value="PurH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024051">
        <property type="entry name" value="AICAR_Tfase_dup_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011607">
        <property type="entry name" value="MGS-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036914">
        <property type="entry name" value="MGS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002695">
        <property type="entry name" value="PurH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11692">
        <property type="entry name" value="PTHR11692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01808">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02142">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000414">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00798">
        <property type="entry name" value="AICARFT_IMPCHas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00851">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52335">
        <property type="entry name" value="SSF52335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00355">
        <property type="entry name" value="purH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51855">
        <property type="entry name" value="MGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 8" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="5 8" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MGS-like" evidence="9">
        <location>
            <begin position="1"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL78743.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="499" mass="53753" checksum="706F97D004A597DF" modified="2016-01-20" version="1">MPKAILSVYDKSGVEAFARTLAASGWELLASGGTARLLKQAGLAVQEVSDYTGSPEILGGRVKTLHPAIHGGILARDLPEDQAQLDALGWGNIDLVVVNLYPFQATIARPGVTLAEAIENIDIGGVALIRAAAKNHERVMLVCDPKDYPAVLEELKSGNAGEQFRRQLAVKGFCLTAAYDQAIAAYLSGEPVESLTLYPLQTLRYGENPHQHAAVYGFEAGQGPLGGEVLQGKELSYNNLLDLDAAWRAAVSYTRPSVCIVKHLSPCGIASAEHLVDAYLAALESDPVSAFGGVVACNREVDEETAEQISQIFVECVIAPSFSGGAREIFEKKKNLRLLKMPDLRIEPDYELRSITRGILKQSVDFGDPAETEWKVATKREPGQEEWQSLRFAWKACQHVKSNAIVFCQGEATVGIGGGQPNRVDCVRIAAQRAGDKARGAVMASDAFFPFADSIEEASRAGITAIIQPGGSIRDLESIEAADRLGIAMVFTGVRHFRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9W7</accession>
    <name>A0A0P6X9W7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_10560</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062964.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77005">
        <property type="protein sequence ID" value="KPL77005"/>
        <property type="gene ID" value="ADN00_10560"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019587">
        <property type="entry name" value="Polyketide_cyclase/dehydratase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10604">
        <property type="entry name" value="Polyketide_cyc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL77005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="150" mass="17378" checksum="16A6A4B7700755A3" modified="2016-01-20" version="1">MHFNLTIPIRRTPEEVFAFLRDKHAFPRQRGSPVLELEKITPGAVGIGTRFREVVRMLPLVRGEIFSRVTRFEPYRCLQEEFWGAGMSGWLTYTFNPHEGGTLLVQDQIIEVDGLLKLLMPLMRAVLVRRLRGRLIEIHNLLEDGWPVTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAQ1</accession>
    <name>A0A0P6XAQ1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061860.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79209">
        <property type="protein sequence ID" value="KPL79209"/>
        <property type="gene ID" value="ADN00_05030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="210"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="290"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="323"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="361"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="388"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="679" mass="78144" checksum="E34B7D4277B03C54" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAR8</accession>
    <name>A0A0P6XAR8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_15710</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063979.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72262">
        <property type="protein sequence ID" value="KPL72262"/>
        <property type="gene ID" value="ADN00_15710"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="112" mass="12553" checksum="9F77FD5E9EC3C58C" modified="2016-01-20" version="1">MTSFAHLAWKSAVLQKPADIVDGKRSSAWSKLADVMVTPLMPVSSETIRRMELQSPTKVYEVYLQSETRLAISEGCSVVVDGETYLVKGVSPWDDFRGQTTYQLVIEDVINR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAS8</accession>
    <name>A0A0P6XAS8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_15820</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72280.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064000.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15820"/>
    <dbReference type="EnsemblBacteria" id="KPL72280">
        <property type="protein sequence ID" value="KPL72280"/>
        <property type="gene ID" value="ADN00_15820"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902531">
        <property type="term" value="P:regulation of intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="454"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="8">
        <location>
            <begin position="690"/>
            <end position="803"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="8">
        <location>
            <begin position="810"/>
            <end position="927"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="140"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="253"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="4">
        <location>
            <position position="739"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="4">
        <location>
            <position position="860"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL72280.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="932" mass="102802" checksum="62206EC933589482" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XB46</accession>
    <name>A0A0P6XB46_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_02965</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000013">
        <property type="protein sequence ID" value="KPL79401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061465.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000013.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02965"/>
    <dbReference type="EnsemblBacteria" id="KPL79401">
        <property type="protein sequence ID" value="KPL79401"/>
        <property type="gene ID" value="ADN00_02965"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2229"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="211" mass="23499" checksum="815915B1ADE0D8DE" modified="2016-01-20" version="1">MIKDLIWDLDGTLFDTYPAVVRAFQSVFRAYHIDLPDEQVLSLTRVSYRNCANVVASAHGLDAARIMQLFDQAYLQIPLKTQPPFPGAPELCRWTVARGGRNVIVTHRAESTSLRLLEGFNLRGLFAGWVTGDMGFPRKPNPASFLAALQRFDLQPATALALGDRDLDLQAALAAGVRYTCAFGSDPFETRADFFVTDFRDLPPLLERHQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBD0</accession>
    <name>A0A0P6XBD0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Type-4 uracil-DNA glycosylase</fullName>
            <ecNumber evidence="3">3.2.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">ADN00_01885</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil.</text>
            <dbReference type="EC" id="3.2.2.27"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 4 (UDGa) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.27" evidence="3"/>
    <dbReference type="EMBL" id="LGCL01000007">
        <property type="protein sequence ID" value="KPL80045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061268.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000007.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01885"/>
    <dbReference type="EnsemblBacteria" id="KPL80045">
        <property type="protein sequence ID" value="KPL80045"/>
        <property type="gene ID" value="ADN00_01885"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2303"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004844">
        <property type="term" value="F:uracil DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005273">
        <property type="entry name" value="Ura-DNA_glyco_family4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005122">
        <property type="entry name" value="Uracil-DNA_glycosylase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03167">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00986">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="SSF52141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00758">
        <property type="entry name" value="UDG_fam4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDG" evidence="10">
        <location>
            <begin position="31"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="189"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00019403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL80045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="217" mass="23574" checksum="33412B381501E99A" modified="2016-01-20" version="1">MDPAEVLLEVSRQVSNCKRCGLHFSRKKPVPGSGQANAKIMFIGEGPGFYENQQGLPFVGAAGKFLDELLAAAGLRREAVFITNVVKCRPPGNRDPQADELAACNDYLDRQINAINPALIVTLGRFSMAKFLPNAKISEVHGQTRWVKDRLVVAMYHPAAALHQPTLRPVVEADFARLPEFVKMAESHRPAAQAASPAAEAEPSEEDLGSATQLSLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBS8</accession>
    <name>A0A0P6XBS8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">NADH dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_15465</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I 51 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063935.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15465"/>
    <dbReference type="EnsemblBacteria" id="KPL72220">
        <property type="protein sequence ID" value="KPL72220"/>
        <property type="gene ID" value="ADN00_15465"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.795"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11540">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001949">
        <property type="entry name" value="NADH-UbQ_OxRdtase_51kDa_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011538">
        <property type="entry name" value="Nuo51_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037225">
        <property type="entry name" value="Nuo51_FMN-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019575">
        <property type="entry name" value="Nuop51_4Fe4S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037207">
        <property type="entry name" value="Nuop51_4Fe4S-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01512">
        <property type="entry name" value="Complex1_51K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00037">
        <property type="entry name" value="Fer4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10589">
        <property type="entry name" value="NADH_4Fe-4S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00928">
        <property type="entry name" value="NADH_4Fe-4S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140490">
        <property type="entry name" value="SSF140490"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF142019">
        <property type="entry name" value="SSF142019"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00645">
        <property type="entry name" value="COMPLEX1_51K_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="6">
        <location>
            <begin position="538"/>
            <end position="567"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="6">
        <location>
            <begin position="568"/>
            <end position="595"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL72220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="595" mass="64752" checksum="A62B434F67AD454C" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBX7</accession>
    <name>A0A0P6XBX7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH tetR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_09160</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062693.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77292">
        <property type="protein sequence ID" value="KPL77292"/>
        <property type="gene ID" value="ADN00_09160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023772">
        <property type="entry name" value="DNA-bd_HTH_TetR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01081">
        <property type="entry name" value="HTH_TETR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="11"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="247" mass="28256" checksum="08B4F1F53F783F4C" modified="2016-01-20" version="1">MPRVIKPEEHQQKHDEILDVAQRLVYTIGYEQMSIQNIIQELGISKGAFYHYFDSKQALLEAMVDRIMAEMEKFLIPIVNDPQIPALEKIERFFDSAARWKSARKEFLTSLLKTWYADENAIVRQKLTAASTRWLTPFLVQIFNQGVDEGVFDIEFCDQTARACITIMTSLGEDIAAGLLNMRPDDTLERQMEALKAMEKSILAYRVAIERVLGAPRDSITLFNLDLLREWVLTVDPPSASTIPSID</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XCC5</accession>
    <name>A0A0P6XCC5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_01510</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061194.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80548">
        <property type="protein sequence ID" value="KPL80548"/>
        <property type="gene ID" value="ADN00_01510"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1058"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="201"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="248"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="284"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="329"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL80548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="359" mass="37605" checksum="553D84D9B96BEFF4" modified="2016-01-20" version="1">MPEKPDLKRILNRTIEALLPLVGLLLALLIGAGMLLALEVNPLVAYSALIDGAVGGTSSITQTLVKATPLLLVGLGVVISYRGGVINIGGEGQLIVGALAATALAIGFNHLPRIILLPSCLIVGAAAGALWGGIPGLLKSRMEVNEILSTVMMNAIALQFSNFLLRGPMIDPAEIEAGTRIAQSALLPEAAWLTRLVPKTLLHSGAILAVILAVAVYVFLWRTTIGYRIRAVGLNPHASRYAGINVPFYQAISLTLGGLFAGLAGAVEVMGVQHRMLEGLSGGYGFSGIVAALFGQLHPLGTIPASVLFGGLIVGGNKMQRAVQVPSSLITAMLGLMVLFVVSANIWARVRARRREMHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XCE7</accession>
    <name>A0A0P6XCE7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_02015</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Involved in DNA recombination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RmuC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000007">
        <property type="protein sequence ID" value="KPL80069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061294.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000007.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02015"/>
    <dbReference type="EnsemblBacteria" id="KPL80069">
        <property type="protein sequence ID" value="KPL80069"/>
        <property type="gene ID" value="ADN00_02015"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003798">
        <property type="entry name" value="DNA_recombination_RmuC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02646">
        <property type="entry name" value="RmuC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="6"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="299"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL80069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="399" mass="43415" checksum="CF6B8B1016B9CA07" modified="2016-01-20" version="1">MTDMELMIAAAVVVVGLVLLALVGLAVAILVQLRRGANDPQGLAVSLKDLTRGLQQEQAQIGALHERVGQIQPLVQHVSSLQTDVRGLAERISTVERSQGTVHRGVGELATQSISALSELRSLTNQLASATVTMRAELNQARSDLTALHASDRTRQEEERRMAESLRRLETVIAGTQSKGAAGENIVEAVFARLPVEWQVRNFMVGGRPVEFGLRLPNGLVLPIDSKWAATGLLEQFLASEVVDEQARLKREIENAVLAKAREVRKYIDPGLTLNFGLAVVPDAIYDLCFGVLPEVFQMGVVLVSYSMLVPYLMLVFQTVLRSDQSIDLYRLEAYIQTVQSSTEAIQLELDGRFARAMTMLANSRDDIRAHAGRASASLSGLKVGGKPLEAGSGIELEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDD3</accession>
    <name>A0A0P6XDD3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminotran_1_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_07245</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062313.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07245"/>
    <dbReference type="EnsemblBacteria" id="KPL78257">
        <property type="protein sequence ID" value="KPL78257"/>
        <property type="gene ID" value="ADN00_07245"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3269"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027619">
        <property type="entry name" value="C_S_lyase_PatB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04350">
        <property type="entry name" value="C_S_lyase_PatB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="1">
        <location>
            <begin position="25"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="387" mass="43510" checksum="18EEA3461181E1D5" modified="2016-01-20" version="1">MPGYFDNTPERRSTNSIKWKAYDKDVLPLWVADMDFLSPPAVIEALRQRVEHGIFGYTYEPQELRDLIVARLKNLYNWEIKPEDIVFLPGVINGFNLACRMIARQHPNSQVIVQPPIYPPFLVAAEHNDLHRLDIPLVDTGSGYYEIDFEAFEQAITPQAKLFILCNPHNPVGRVFTRAELTRLAEICERHDVLICSDEIHCDLIFSGQQHIPVASLSPEIASRTITLMAPSKTYNIAGLEGSFAVISDPETRHAYEKARAGLTGHINLLGVTAAIAAYQDGQSWLSELLAYLESNRDFLASYIQQNLPGISMFSPEGTYLAWINCREARIPGNPQRFFLENARVAMNNGDDFGIGGQGFVRLNFGTSQAILRDALERMRTALSQLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDF9</accession>
    <name>A0A0P6XDF9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01265</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000003">
        <property type="protein sequence ID" value="KPL80846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061149.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000003.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80846">
        <property type="protein sequence ID" value="KPL80846"/>
        <property type="gene ID" value="ADN00_01265"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="264" mass="28814" checksum="196B542CD90B1E06" modified="2016-01-20" version="1">MAGLSFIHHLRETLSEIENNLTDGIAAISPWITPLPSAALVANAVVQDLHWNQALGWITAAIIESLGLTTVSTSLQLWDYNTAKRKTDPGAPFMLAALLVGVYLFSTIGLTVLLDIFPEMGRYAPALFPLLALVGAVNLALRSGHRRRLAGIAQDRADRKAERQSLRPSAGNLTDLLTSNTTSNSVYPDNSLAKARQARTAIQGNRLDNLLTLYRDNPTIGVTDAARTLNMSRQTIYTYLDRLESDGRIRRNGHGIEVIGEDAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XEJ7</accession>
    <name>A0A0P6XEJ7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_14665</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000035">
        <property type="protein sequence ID" value="KPL73579.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063780.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000035.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14665"/>
    <dbReference type="EnsemblBacteria" id="KPL73579">
        <property type="protein sequence ID" value="KPL73579"/>
        <property type="gene ID" value="ADN00_14665"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007497">
        <property type="entry name" value="DUF541"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04402">
        <property type="entry name" value="SIMPL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133009" evidence="1">
        <location>
            <begin position="23"/>
            <end position="244"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL73579.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="244" mass="25546" checksum="BE37CC8030712354" modified="2016-01-20" version="1">MKSRILSAVMGIAILLSLAACAVQSPVGSNNSPINRTLNANGVGEVAITPDVAYIFVGVRSQAENVEDALDQNNKQSAAVSSALQELGVDPLDIQTSAFNIYPQQFYGPMGPTSPEDMGTTMYVVENTVYITVRDLQKLGGVLNAVVRAGANNINGINFDVSDKSEAIAQARKLAIDAAKSKAQAIAADAGIQLGDLITLNVYENQNVVPLYEGKYVGGAGAGVPVSAGQMKVQVTADLIYEIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XFM4</accession>
    <name>A0A0P6XFM4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 2">Hypoxanthine phosphoribosyltransferase</fullName>
            <ecNumber evidence="1 2">2.4.2.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_03555</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>diphosphate + IMP = 5-phospho-alpha-D-ribose 1-diphosphate + hypoxanthine</text>
            <dbReference type="Rhea" id="RHEA:17973"/>
            <dbReference type="ChEBI" id="CHEBI:17368"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="EC" id="2.4.2.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; IMP biosynthesis via salvage pathway; IMP from hypoxanthine: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.8" evidence="1 2"/>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78980.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061589.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03555"/>
    <dbReference type="EnsemblBacteria" id="KPL78980">
        <property type="protein sequence ID" value="KPL78980"/>
        <property type="gene ID" value="ADN00_03555"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.62"/>
    <dbReference type="UniPathway" id="UPA00591">
        <property type="reaction ID" value="UER00648"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052657">
        <property type="term" value="F:guanine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004422">
        <property type="term" value="F:hypoxanthine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032264">
        <property type="term" value="P:IMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005904">
        <property type="entry name" value="Hxn_phspho_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01203">
        <property type="entry name" value="HGPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="3">
        <location>
            <begin position="20"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU364099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL78980.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="187" mass="21100" checksum="58FE2A1F5E13C47E" modified="2016-01-20" version="1">MVRDYHEFLGEVLVSEEDLQARVAELGREISRDFEGKELLLVCILRGGVLFLTDLMRHISVPHAIEFMAVSSYGTGARESTGQARITLDVNTDIRDRHVILVEDIVDSGHTLASVLELLSMRKPASLAVCTLLDKAERREVEVPILYRGFEIPNKFVFGYGLDIDEFYRNLPFIGVVDLQKYDGNAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XG33</accession>
    <name>A0A0P6XG33_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_18250</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064483.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70008">
        <property type="protein sequence ID" value="KPL70008"/>
        <property type="gene ID" value="ADN00_18250"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="69" mass="7718" checksum="F1E36D3A8884AF38" modified="2016-01-20" version="1">MTKEIEEKVFGTAVEKSAHTLGLLVGQEVFQGMIEALDERMANKKPAGWRNIDTEKRRMVSSSGTMGYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XG84</accession>
    <name>A0A0P6XG84_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05305</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061933.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78672">
        <property type="protein sequence ID" value="KPL78672"/>
        <property type="gene ID" value="ADN00_05305"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1534"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020471">
        <property type="entry name" value="AKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00069">
        <property type="entry name" value="ALDKETRDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="15"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="334" mass="37741" checksum="7E376E2822B1E1BE" modified="2016-01-20" version="1">MEYRYLGRSGLKVSELCLGAMTFGRESSKEESFRIMDLFVEAGGNFIDTANVYSLGTSEEIVGQWLRGKQRDDLVIATKARFPMGKGPNDEGLSRKHLMKAVDDSLRRLGSDYIDLYQVHCWDRRTPLEETLITLDTLVKSGKVRYLGASNFTGWQLQKAIDLSRQMGLEAFTSLQPLYNLLDRYSEWELMAVCRNEGLGVLPWSPLRGGWLSGKYQRSMSAPPQGSRVEEASKQGWSEAWDEYANEHTWSVIDALMSAAKDLDKHPAQVAIRWLLQRPGVTSPIIGARKPEHLQINLGASGWIIPEAVMQQLNAASDMKPPYPYAFIRAYQRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGB0</accession>
    <name>A0A0P6XGB0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Sugar-bind domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_05600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SorC transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061988.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78718">
        <property type="protein sequence ID" value="KPL78718"/>
        <property type="gene ID" value="ADN00_05600"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007324">
        <property type="entry name" value="Sugar-bd_dom_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04198">
        <property type="entry name" value="Sugar-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sugar-bind" evidence="2">
        <location>
            <begin position="62"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="322" mass="34973" checksum="0DD9DA5C3F01876A" modified="2016-01-20" version="1">MARVDELRVISRIARMYYELGIKQSEISRQLGISQATVSRFLERAKDEGIVRISVTIPAGVNSELEETLIHQYKLRDAIIVDCYSDTDESIINRDIGAAAAYYLETAINHNEVIGISSWSSALLALVDAFHSIQKRNNIRVIQILGGVGNPTAEAHANRLTSRLAGLVSGEAVFLPVPGILGSGNSLKVLEQDPYVQKAIQMFDEVTLALVGIGALQPSNLLKASGNIFTDEELALLSSKGAVGDALLRFFDINGKAVQTELSNRVFSMKLEQLQKVERAIGVAGGVRKRAAILGALRGRYINILITDKCTAQWLAEEGGKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGH4</accession>
    <name>A0A0P6XGH4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_06255</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062105.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06255"/>
    <dbReference type="EnsemblBacteria" id="KPL78819">
        <property type="protein sequence ID" value="KPL78819"/>
        <property type="gene ID" value="ADN00_06255"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027839">
        <property type="entry name" value="DUF4432"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14486">
        <property type="entry name" value="DUF4432"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="362" mass="40202" checksum="0AA6025379119B19" modified="2016-01-20" version="1">MNATISLRKEWFSEKEQRLVTAGELAASLFCFESGVQAVRLSNVLGELVLLPYQGQQIWSAMFHGRELAMKSMFDQPYPTRDFLSNFGGFLVHCGVLAMGSPSAEDSHPLHGELPNAPYQKAQLLLGEDEKGTYIALTGENRHTVAFNASYTARPCVKLYANSAIFDVSMTVTNLKNSDMPLMYLAHVNFRPEVNARLAQSVLPNPQAMRVRADVPAFMQTPAGYREFLAELKLHPEKHLALTPDLKFDPEVVFYFDYLADEQGWARTLQIHADGSADVVRHKPAQLNRGVRWICRTVDQEALGFEPATAEVEGFRAEEKKGNVRVLGGGESFFCELQVGLLTFSEAAEEERAIARAISAVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGI0</accession>
    <name>A0A0P6XGI0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Ferritin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_06310</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062115.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78828">
        <property type="protein sequence ID" value="KPL78828"/>
        <property type="gene ID" value="ADN00_06310"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1764"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01052">
        <property type="entry name" value="DPSL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014490">
        <property type="entry name" value="Dps-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033921">
        <property type="entry name" value="DPSL_diiron-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009040">
        <property type="entry name" value="Ferritin-like_diiron"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008331">
        <property type="entry name" value="Ferritin_DPS_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00210">
        <property type="entry name" value="Ferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF018063">
        <property type="entry name" value="Ferrtn_UCP018063"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50905">
        <property type="entry name" value="FERRITIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ferritin-like diiron" evidence="2">
        <location>
            <begin position="10"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR018063-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="165" mass="18657" checksum="410B53F94D8D4C72" modified="2016-01-20" version="1">MGTKGRSIVGMDVDELLATLNRAFADEWLAYYQYWLGAKVVKGPMKDAVASELLLHATEELSHADMLAARIIQLGGTPLITPEEWFKNTHCGYDAPTDAFVKEILAQNIKGEQCAIDVYQKVLEMVKDKDPVTYNIVLTILEQEVEHEEDLQSLDEDIEMLMIRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGU2</accession>
    <name>A0A0P6XGU2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13945</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063640.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000033.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74103">
        <property type="protein sequence ID" value="KPL74103"/>
        <property type="gene ID" value="ADN00_13945"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="82" mass="8663" checksum="E4ACF0CE1E0A9C89" modified="2016-01-20" version="1">MAAKAADTQLKQVAQRLAAAHPLGAVGEALAYCRLPDGRVVVVDSQGHKLVFSAEEAARAAGEILGGPRRPPVKEAKHERVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XH99</accession>
    <name>A0A0P6XH99_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Beta_helix domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74822">
        <property type="protein sequence ID" value="KPL74822"/>
        <property type="gene ID" value="ADN00_13340"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039448">
        <property type="entry name" value="Beta_helix"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012334">
        <property type="entry name" value="Pectin_lyas_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13229">
        <property type="entry name" value="Beta_helix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="SSF51126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta_helix" evidence="1">
        <location>
            <begin position="150"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="300" mass="32092" checksum="9B04C4C5D3CAE96F" modified="2016-01-20" version="1">MLHRRKTNHQHFLVVLVFWEGEMKKQAVFLMIAVFLLTSGMKGLNSVSLTAADVDGAEDIEFAIRQATADGTLPGRVVLDNSQGDFVFSTDDKTINIFVPNLTLISKNGAVIKNCEGAINFDALPASNVTIEGIRFLCSGDGISSSDYPNAGIRIVKNEIYVQGIGLDLGSLNNATIADNKITGKVGVRLDESSSALKVSHNQIDAVSIGIAVQGSDWNQVVENRIAAGWQGILLSGEADFNQVLANKISRVEQSGVALDGDPFGNQILGNKVVCSIGAECKAVDAQMELIEQNHIKGNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XHT6</accession>
    <name>A0A0P6XHT6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_02385</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000010">
        <property type="protein sequence ID" value="KPL79665.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061360.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000010.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02385"/>
    <dbReference type="EnsemblBacteria" id="KPL79665">
        <property type="protein sequence ID" value="KPL79665"/>
        <property type="gene ID" value="ADN00_02385"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2694"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003797">
        <property type="entry name" value="DegV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043168">
        <property type="entry name" value="DegV_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02645">
        <property type="entry name" value="DegV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00762">
        <property type="entry name" value="DegV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51482">
        <property type="entry name" value="DEGV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79665.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="286" mass="31681" checksum="2E57DEB52476D29F" modified="2016-01-20" version="1">MSQYKIALVCDSTHDLPQELIDRYQIHVVPLYIIWNGQVLKDGVDIRPERFYEQLVAHPDAFPSTSQPSPQDFARVYQQLVADGAQEIVVLTISSAMSGTIDSARQAGLQMDIPVHIHDTKSNSMSIGWQLLAAARARENGASAQEMIAAADQVRQKLVYIISLNTLEYLHRGGRIGGAATFIGQLLNLKPQIFVNHQTGAVEAGVPTRTRKRALEVLYQNFFKQVDASRPLRIAVLHNNAREAAEQLAERIRQEFHPEELIISIVSPILGTHTGPEAVALCGYSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XJB6</accession>
    <name>A0A0P6XJB6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_02025</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000007">
        <property type="protein sequence ID" value="KPL80071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061296.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000007.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02025"/>
    <dbReference type="EnsemblBacteria" id="KPL80071">
        <property type="protein sequence ID" value="KPL80071"/>
        <property type="gene ID" value="ADN00_02025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006865">
        <property type="term" value="P:amino acid transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001123">
        <property type="entry name" value="LeuE-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30086">
        <property type="entry name" value="PTHR30086"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01810">
        <property type="entry name" value="LysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="66"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="145"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="179"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL80071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="204" mass="22154" checksum="3201341ECB48F7FF" modified="2016-01-20" version="1">MLAFITQGLLLGIYAGATPGPFLAFLMAQSLRVGWRRTLPAAFAPLLSDSPAILLCIFILSQTPDWFISALRLVGGGVLLWMAYGTLSTARQNSLTEPSAANESSRSLIRATLMNLFNPNIYIFWSTIGAPIVLDGFKYSRIHGFSFIVAMYATLIPTLAVIIFLSGAANRFTPRVRTILSYALGGMLVLFGLYQISQGLIALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XK61</accession>
    <name>A0A0P6XK61_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_01600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80565">
        <property type="protein sequence ID" value="KPL80565"/>
        <property type="gene ID" value="ADN00_01600"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL80565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="73" mass="8405" checksum="75E9CFBD7475472C" modified="2016-01-20" version="1">MWITARSTHQHPISGGKPKVTFSILRNLSGAFVHNRLWITGKRFHIFFLGQEQLGEQIQILGVVNLYPYIWGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKF0</accession>
    <name>A0A0P6XKF0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_12635</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12635"/>
    <dbReference type="EnsemblBacteria" id="KPL75493">
        <property type="protein sequence ID" value="KPL75493"/>
        <property type="gene ID" value="ADN00_12635"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1219"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL75493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="485" mass="52929" checksum="CA6332A5C68273DE" modified="2016-01-20" version="1">MSDTQSYAILQYPDVDQVYRQLNRLVSQPLRPVRRDRMQAYLQYFDTRCARSKALIDEAKKVIPGGVQHNLAFNYPFPIAIERADEAHLWDVDGNRYIDFLQAGGPTILGSNYLPVREKVIEMLQSCGPVTGLFHEYELKLAQLIQKFMPSIEMFRMLGSGTEGVMAAIRAARAFTGRRKVIKVGGAYHGWSDSMVYGLHIPGTGRLEAKGIPAGASANTQEFFPNALGALRRRLFLNQLTGGTAAVIVEPLGPESGTRPVPFDFNQKVRELCDEFGALLIFDEVVTGFRVGLGGAQGYFGVKPDLTVFGKCLTGGYPMAGGVGGRAEVIQRFAAGIGGTGERAYIGGTLSANPISCVAGYHALLEMERTNAAVIAGRAGDRLTKGLQAIIDKYNLPFVVFNQGSIVHLETSGVMLLDLRNPVRLARELKTRKHMMEEMGAAYMANGLITLAGSRMYTSMADTDEVIDDALARFEQVLSSVEGVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKG6</accession>
    <name>A0A0P6XKG6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_12755</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063404.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000027.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL75511">
        <property type="protein sequence ID" value="KPL75511"/>
        <property type="gene ID" value="ADN00_12755"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="494"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="498"/>
            <end position="530"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL75511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="530" mass="58129" checksum="80ADE783D0CC9736" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKW6</accession>
    <name>A0A0P6XKW6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_15740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063985.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72267">
        <property type="protein sequence ID" value="KPL72267"/>
        <property type="gene ID" value="ADN00_15740"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.854"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="260"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="455" mass="51603" checksum="801260DD3A2A2742" modified="2016-01-20" version="1">MNPLELAVQSALKANAYQLDLFAKAGTINHPRGVIMTAYRNARRSMRQALMDRNKIWAANEVMTALIRTIRFEIAPLLEKAQLYGLRDAQKQLEFYGVKPTDDFMALGLQAQREAALDAVVGTVEQQWKTTKGILQVGSDVDLILGDEERIGVLRPGDPIASVSTWISSLMWTTWGGVVQTSTKQKNRIEKLAVVAVDSRTTDCCLNVHGQHVPFDEPFHLTGTPRYADHLDWSPFHNYCRTSIALYYEDYDDGITDQMKKEAGSEKDRRGEDKRRKLAGLSPLDRSSPKKIRSYRVAKPGGADIETPTPTALSKAWCNGSWYRTPTHMKWAVKEEFGLKTWVWDPKNTAIDQNLVKALQPTIRQMYNQTQEFFRSQGVTSVRLYRGLKNPTDMFSVLESWTSDYSTAARFDGFTVLVEDIPIHRIFMAHVGPNWVNGKFGNQFEYIVLPPEFEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XL73</accession>
    <name>A0A0P6XL73_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF2007 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_00295</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060957.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL81022">
        <property type="protein sequence ID" value="KPL81022"/>
        <property type="gene ID" value="ADN00_00295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018551">
        <property type="entry name" value="DUF2007"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09413">
        <property type="entry name" value="DUF2007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2007" evidence="1">
        <location>
            <begin position="8"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL81022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="87" mass="9370" checksum="B085412DC0911CFE" modified="2016-01-20" version="1">MTTFNYVDVYEAQGFLAAEMIRLYLESAGIDAKVAQESAGLAIGLTVGPLGLAKVLVRADQADEAVRLIMEMESSTNDLVDDSDEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XLL2</accession>
    <name>A0A0P6XLL2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Sec-independent protein translocase protein TatC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">tatC</name>
        <name evidence="6" type="ORF">ADN00_11775</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Forms a complex with TatA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TatC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063214.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11775"/>
    <dbReference type="EnsemblBacteria" id="KPL76032">
        <property type="protein sequence ID" value="KPL76032"/>
        <property type="gene ID" value="ADN00_11775"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033281">
        <property type="term" value="C:TAT protein transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043953">
        <property type="term" value="P:protein transport by the Tat complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00902">
        <property type="entry name" value="TatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019820">
        <property type="entry name" value="Sec-indep_translocase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002033">
        <property type="entry name" value="TatC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30371">
        <property type="entry name" value="PTHR30371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00902">
        <property type="entry name" value="TatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01840">
        <property type="entry name" value="TATCFAMILY"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00945">
        <property type="entry name" value="tatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01218">
        <property type="entry name" value="TATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0811">Translocation</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="73"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="103"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="156"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="188"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="212"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL76032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="243" mass="26388" checksum="CE0FCD839EBB68BB" modified="2016-01-20" version="1">MADEPATMSLLDHISELRRRLLISLVALAVTSLASFSLAGRIVEALAKPIGGLDKLQAIEVTETIGVFMRVSLLSGIILAMPILLYEALAFILPGLTPGEKRWVLAAIPTASLLFVAGAAFSYFIMLPPSIDFLISFMDVATVPRLSDYMKFVTNLIFWIGISFQLPLIAFLLAKVKLINAGMLGRHWRIAVIVISILAAVISPTVDPINMALLMLPLLILYLLSVLLAAIANPKPRGKDLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XMC6</accession>
    <name>A0A0P6XMC6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">tRNA N6-adenosine threonylcarbamoyltransferase</fullName>
            <ecNumber evidence="6">2.3.1.234</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">N6-L-threonylcarbamoyladenine synthase</fullName>
            <shortName evidence="6">t(6)A synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaD</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">tRNA threonylcarbamoyladenosine biosynthesis protein TsaD</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">tsaD</name>
        <name evidence="8" type="ORF">ADN00_18670</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>adenosine(37) in tRNA + L-threonylcarbamoyladenylate = AMP + H(+) + N(6)-L-threonylcarbamoyladenosine(37) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:37059"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10163"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:73682"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74418"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.3.1.234"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="6">Binds 1 Fe(2+) ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the KAE1 / TsaD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.234" evidence="6"/>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064554.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18670"/>
    <dbReference type="EnsemblBacteria" id="KPL70073">
        <property type="protein sequence ID" value="KPL70073"/>
        <property type="gene ID" value="ADN00_18670"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3043"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061711">
        <property type="term" value="F:N(6)-L-threonylcarbamoyladenine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01445">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000905">
        <property type="entry name" value="Gcp-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017861">
        <property type="entry name" value="KAE1/TsaD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022450">
        <property type="entry name" value="TsaD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735">
        <property type="entry name" value="PTHR11735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11735:SF6">
        <property type="entry name" value="PTHR11735:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00814">
        <property type="entry name" value="TsaD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00789">
        <property type="entry name" value="OSIALOPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00329">
        <property type="entry name" value="gcp_kae1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03723">
        <property type="entry name" value="T6A_TsaD_YgjD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="4 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 6" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TsaD" evidence="7">
        <location>
            <begin position="33"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="149"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="288"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="313"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL70073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="345" mass="36381" checksum="590BCEBFBB51CC90" modified="2016-01-20" version="1">MDEQIFPPARILGIESSCDETSAAVIANGREPLSIVTATQIEMHAQFGGVFPEVASRQHIKTVYGVIEQALQQAHMSLSDVDAIAVTLGPGLAGSLVVGVNAAKGLAVASGLPLVGVNHLEGHIYSAWLRPPEMADLPPAPQFPLLALLVSGGHTELNLITNHLEYQRLGGTLDDAAGEAFDKVARLLGLPYPGGPSIQEAAKNGNPRTFQFPRSMLEGTWNFSFSGLKTAVLRAVQNFKNDPENLPVNDLAASFQTAVVDVLVSKTLAAAKAYGAKEILLAGGVSANAALREGFRKHSPIKVNIPDLSYCTDNAAMIAAAGYFRFVAGHVSDLDVDVLPNLSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XN53</accession>
    <name>A0A0P6XN53_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Peptidase M29</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ADN00_08465</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase M29 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062551.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08465"/>
    <dbReference type="EnsemblBacteria" id="KPL77894">
        <property type="protein sequence ID" value="KPL77894"/>
        <property type="gene ID" value="ADN00_08465"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.696"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1830.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035097">
        <property type="entry name" value="M29_N-terminal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000787">
        <property type="entry name" value="Peptidase_M29"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02073">
        <property type="entry name" value="Peptidase_M29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00919">
        <property type="entry name" value="THERMOPTASE"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL77894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="369" mass="41985" checksum="87BCE2CF04E4833C" modified="2016-01-20" version="1">MRDLRVDKLAELLVNYSLEIQPGEKTLIWADTPSAPLIQATYEQIIHQGAFPFVYAVLPGLAEALLEYGTDEQIRFTPEPFAQIFETFDSMVFIRSLENTRFLGRADAAKVVEREKGLGKLRKIYTERTAKGQFRWVLTLFPTNAHAQDADMALRDYENFVFNACLPDLNDPVSYWKEVSAYQARIIEWLKGKERVHVLGKDTDLRLRIDNRKFINCDCHVNVPDGEVYTGPVEDSLEGHVHFSYPAIYRGKEVLGVRLQFEKGKVVSATADKNEAYLNKMLDTDAGSRYVGEFAIGTNKMIQQFTGQILFDEKIGGSFHMAMGNGYPETGSINQSLIHWDMICDLRDGGQIWVDDQLIYENGDFVLDI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XPK7</accession>
    <name>A0A0P6XPK7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13995</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13995"/>
    <dbReference type="EnsemblBacteria" id="KPL74113">
        <property type="protein sequence ID" value="KPL74113"/>
        <property type="gene ID" value="ADN00_13995"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1897"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="SSF48264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0349">Heme</keyword>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="461" mass="52213" checksum="8D1331090E698E10" modified="2016-01-20" version="1">MNQETSPTLSVISARQLLPQLRALQQNTIGFLLETTRQHGDLVLFDLGTQRAVLVNDANLVKQILQDRHPHYDKNTIQYNMLATVTGRGLLTADGEDWFKHRRMQQPAFVRPRLETSLVPHIVPAAQRMLDRWQTAAQRGELLDVDREMMDVALEVVGQALFSLDLSRDARRLTSAVLVCLDHIIHLARNPHLSLLPDWLPQPGGQKFKRALKELNLSVEEIIHQRRAAGGPPPDDLVTMLLNARDPESGEGLSDAQIRDELITILIAGHETVASALTWTWLLLAQNPDAFQRLRAEVQSVLPDRDPTAEDLQRLPYTAAIFDEALRLYPPAWLITRRVVEADSYYDVRVDPGTLVILSPYALQRHPRYWPDPHAFRPERFLPDATKTYPRYAYIPFGGGPRLCIGNHFAKMEAAIIIAMVARRFRLERADSTEVFPESLVTLRPRGGLPMRPIPLSEEAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQ34</accession>
    <name>A0A0P6XQ34_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Fumarate hydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_17375</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I fumarase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71454.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064355.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17375"/>
    <dbReference type="EnsemblBacteria" id="KPL71454">
        <property type="protein sequence ID" value="KPL71454"/>
        <property type="gene ID" value="ADN00_17375"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.539"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008152">
        <property type="term" value="P:metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004646">
        <property type="entry name" value="Fe-S_hydro-lyase_TtdA-typ_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05681">
        <property type="entry name" value="Fumerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00722">
        <property type="entry name" value="ttdA_fumA_fumB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fumerase" evidence="7">
        <location>
            <begin position="7"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF05681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL71454.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="290" mass="31412" checksum="B82F0E1ADB8628F3" modified="2016-01-20" version="1">MADLQDSLVELVRRASVELPEDVRSALKTAAQREAEGSPARMVLGTLLANARLAQERSLPICQDTGTPIFYVSYPLGWSTRELRGQIRAAVAEATRRGFLRPNAVDTLSGLNSGNNLGGDDFPLIHFEESDQAALVIDLLLKGGGCENVGAQYQLPNEQIGAGRDLEGVRRAVLHAVQQAQGLGCAPGVLGVVIGGDRASAYAASKRLFLRRLDDHHPNPDLAALEEQLTAQANQLQIGPMGFGGRVTVLTTKIDSLSRLPASFFVTVSYMCWACRRKRMRLEADEVSYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XRG1</accession>
    <name>A0A0P6XRG1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">UvrABC system protein A</fullName>
            <shortName evidence="13">UvrA protein</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">Excinuclease ABC subunit A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">uvrA</name>
        <name evidence="16" type="ORF">ADN00_08185</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrA is an ATPase and a DNA-binding protein. A damage recognition complex composed of 2 UvrA and 2 UvrB subunits scans DNA for abnormalities. When the presence of a lesion has been verified by UvrB, the UvrA molecules dissociate.</text>
    </comment>
    <comment type="subunit">
        <text evidence="13">Forms a heterotetramer with UvrB during the search for lesions.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="13">Belongs to the ABC transporter superfamily. UvrA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062499.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08185"/>
    <dbReference type="EnsemblBacteria" id="KPL77852">
        <property type="protein sequence ID" value="KPL77852"/>
        <property type="gene ID" value="ADN00_08185"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.638"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009380">
        <property type="term" value="C:excinuclease repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009381">
        <property type="term" value="F:excinuclease ABC activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00205">
        <property type="entry name" value="UvrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004602">
        <property type="entry name" value="UvrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041552">
        <property type="entry name" value="UvrA_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041102">
        <property type="entry name" value="UvrA_inter"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17755">
        <property type="entry name" value="UvrA_DNA-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17760">
        <property type="entry name" value="UvrA_inter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00630">
        <property type="entry name" value="uvra"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 13 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 13" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 13" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 13" id="KW-0228">DNA excision</keyword>
    <keyword evidence="12 13" id="KW-0234">DNA repair</keyword>
    <keyword evidence="11 13" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10 13" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="2 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 13 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 13" id="KW-0677">Repeat</keyword>
    <keyword evidence="13" id="KW-0742">SOS response</keyword>
    <keyword evidence="8 13" id="KW-0862">Zinc</keyword>
    <keyword evidence="7 13" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ABC transporter" evidence="15">
        <location>
            <begin position="382"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="15">
        <location>
            <begin position="629"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="13">
        <location>
            <begin position="263"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C4-type" evidence="13">
        <location>
            <begin position="760"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <begin position="33"/>
            <end position="40"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <begin position="661"/>
            <end position="668"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KPL77852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="976" mass="108418" checksum="B2FCB6D36C6975B9" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XTE1</accession>
    <name>A0A0P6XTE1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Crystallin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_07465</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062426.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07465"/>
    <dbReference type="EnsemblBacteria" id="KPL78355">
        <property type="protein sequence ID" value="KPL78355"/>
        <property type="gene ID" value="ADN00_07465"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3318"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.4080.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005502">
        <property type="entry name" value="Ribosyl_crysJ1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036705">
        <property type="entry name" value="Ribosyl_crysJ1_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03747">
        <property type="entry name" value="ADP_ribosyl_GH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101478">
        <property type="entry name" value="SSF101478"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="706" mass="77279" checksum="652D47BB41F7504B" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XTK2</accession>
    <name>A0A0P6XTK2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_11200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063101.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76527">
        <property type="protein sequence ID" value="KPL76527"/>
        <property type="gene ID" value="ADN00_11200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="165"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="312" mass="34318" checksum="46903CE3681E2B11" modified="2016-01-20" version="1">MTAFQYTHFQLDFLPAIAELQHQRADAGLADVGFLLSPGFEEGRNICVAFDQAGKLAGYASILPHSLSAQWGGAQVLRFDLAARKGLDQEQALKDGFLDWARSRAGELCPADGTPQPVLMARLDAGNLAAVDYLSARGFAYMESEYTLCRDLGVWVVDYAPPAGIEVRAWRMPSQADKETYLAAYQQVFAGSTFCMDDLENFCRSEMWMAGTTFSAFAGEQLVGSVMACYDPNLKRNAERVGLIEHVFVLDGERGRGIGSAMLGQALLYLKQRGLRRAQVDLTASSPEAVCFFESAGFELEREEVFLCLQVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUB8</accession>
    <name>A0A0P6XUB8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_10305</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76966.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062918.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10305"/>
    <dbReference type="EnsemblBacteria" id="KPL76966">
        <property type="protein sequence ID" value="KPL76966"/>
        <property type="gene ID" value="ADN00_10305"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2527"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001670">
        <property type="entry name" value="ADH_Fe/GldA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018211">
        <property type="entry name" value="ADH_Fe_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039697">
        <property type="entry name" value="Alcohol_dehydrogenase_Fe"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496">
        <property type="entry name" value="PTHR11496"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00465">
        <property type="entry name" value="Fe-ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00913">
        <property type="entry name" value="ADH_IRON_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00060">
        <property type="entry name" value="ADH_IRON_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe-ADH" evidence="2">
        <location>
            <begin position="11"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL76966.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="396" mass="42202" checksum="DE639EE963F0553B" modified="2016-01-20" version="1">MLPTYYEFCFPVKIISGHTALNNLPAELVQANVSRPLIISDQGVTRAGLGKIVADAFAESGITIAAIYDEVPPESSTLLVNQLAELYRAKQCDCLIAVGGGSVIDTAKGVNILVSLGGQDVRDYRGAEVLPGPLRAFFVVPTTAGTGSEATNSAVIADPEKGVKMLFVSEFLMPRAAFLDSRMTLTLPPRLTAATGMDALTHAMEAYLSIQKNPMSDAYAWQAVKLIGENLRRVAQNPADKDGRLALANASTMAGTAFSNSMVGCVHSMGHATGGVAHIPHGVAMNIFLPFGLEFNLPRRAEMIAELLMPLAGPETYASTPADQRAKQTIAEVRRLKQDLHEITGLARSLQEAGVRGDQLADIAKLAINDGSAMMNPEELRLEDALELANRAFTQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XV52</accession>
    <name>A0A0P6XV52_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Fructose-1,6-bisphosphatase class 1</fullName>
            <shortName evidence="5">FBPase class 1</shortName>
            <ecNumber evidence="5">3.1.3.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">D-fructose-1,6-bisphosphate 1-phosphohydrolase class 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">fbp</name>
        <name evidence="9" type="ORF">ADN00_04430</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>beta-D-fructose 1,6-bisphosphate + H2O = beta-D-fructose 6-phosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:11064"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="EC" id="3.1.3.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="5">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5 6">Belongs to the FBPase class 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.11" evidence="5"/>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061746.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04430"/>
    <dbReference type="EnsemblBacteria" id="KPL79113">
        <property type="protein sequence ID" value="KPL79113"/>
        <property type="gene ID" value="ADN00_04430"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.242"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042132">
        <property type="term" value="F:fructose 1,6-bisphosphate 1-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016051">
        <property type="term" value="P:carbohydrate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00354">
        <property type="entry name" value="FBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01855">
        <property type="entry name" value="FBPase_class1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044015">
        <property type="entry name" value="FBPase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000146">
        <property type="entry name" value="FBPase_class-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033391">
        <property type="entry name" value="FBPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028343">
        <property type="entry name" value="FBPtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11556">
        <property type="entry name" value="PTHR11556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00316">
        <property type="entry name" value="FBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18913">
        <property type="entry name" value="FBPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500210">
        <property type="entry name" value="FBPtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000904">
        <property type="entry name" value="FBPtase_SBPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00115">
        <property type="entry name" value="F16BPHPHTASE"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FBPase" evidence="7">
        <location>
            <begin position="14"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="FBPase_C" evidence="8">
        <location>
            <begin position="207"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="125"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="122"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="124"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="217"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="249"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="279"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="285"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01855"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF18913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL79113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="350" mass="38064" checksum="688F0FBC817879E0" modified="2016-01-20" version="1">MTLILPSKSGRVVTIERHILETQKYYPQATGVLTNLLYDIALAGKMIASQMSLAGLAQVLGKTGDVNVQGEQVMKLDRLADDIIYHMTATTGRVAVLASEEHEEIIPVPEQTTPGKYILMFDPLDGSSNIDYDAGVGTIFAIYNRVTSEGPGTVDDCLQTGRNLVAAGYIVYGVSTMFVYTTGHGVHGFTLDPSIGEFLLTHENIRIPPEPVYYSTNTGNQEKWSKGVREFTKALHGGNGKAKPLSMRYVGALVVDFHRTLLAGGIFYYPGDKGKPQGKLRLTYEAIPLAYIAEQAGGYASDGCQAILDIRPQQLHQRTPLFVGSSSLVRAAEAYIAKYDKGEECPPPVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XV96</accession>
    <name>A0A0P6XV96_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Type-5 uracil-DNA glycosylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">ADN00_04725</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="8">Belongs to the uracil-DNA glycosylase (UDG) superfamily. Type 5 (UDGb) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061805.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04725"/>
    <dbReference type="EnsemblBacteria" id="KPL79159">
        <property type="protein sequence ID" value="KPL79159"/>
        <property type="gene ID" value="ADN00_04725"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.308"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033958">
        <property type="term" value="F:DNA-deoxyinosine glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004844">
        <property type="term" value="F:uracil DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10031">
        <property type="entry name" value="UDG-F5_TTUDGB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044147">
        <property type="entry name" value="UdgB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005122">
        <property type="entry name" value="Uracil-DNA_glycosylase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03167">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00986">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="SSF52141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDG" evidence="10">
        <location>
            <begin position="60"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL79159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="234" mass="26213" checksum="2CAA022690E3BD4E" modified="2016-01-20" version="1">MAISDNDNCSDPETCLSLAELEACLVNCRACPRLVAWREEVAATRRRAFREETYWGRPVPGFGDPHARLLVVGLAPGAHGSNRTGRMFTGDASGDFLYPALFRAGFASQPTSRRVGDGLELKDVFITAVGRCAPPDNKPTPHELNTCQPYLQAELRLLTQMQGVVALGRIAFERLSRLWGINRLEFVHARLHRLPGRLPWVITSYHPSRQNTQTGRLTEVMFDEVWQTARSLLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XY80</accession>
    <name>A0A0P6XY80_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_00860</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061057.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL81107">
        <property type="protein sequence ID" value="KPL81107"/>
        <property type="gene ID" value="ADN00_00860"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021375">
        <property type="entry name" value="DUF2997"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11211">
        <property type="entry name" value="DUF2997"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL81107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="72" mass="7887" checksum="E3E7AE0C5D591685" modified="2016-01-20" version="1">MDLQEIEITISKNGEVELHVRGVKGEACLDLTRDLEAALGNKVISRELTPEAIESSSSAAAIRPQEKNRARK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y064</accession>
    <name>A0A0P6Y064_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">D-xylose transporter subunit XylF</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">xylF</name>
        <name evidence="3" type="ORF">ADN00_13560</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13560"/>
    <dbReference type="EnsemblBacteria" id="KPL74855">
        <property type="protein sequence ID" value="KPL74855"/>
        <property type="gene ID" value="ADN00_13560"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1207"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025997">
        <property type="entry name" value="SBP_2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13407">
        <property type="entry name" value="Peripla_BP_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133293" evidence="1">
        <location>
            <begin position="34"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="Peripla_BP_4" evidence="2">
        <location>
            <begin position="50"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL74855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="380" mass="40708" checksum="78B971401BEBA8CA" modified="2016-01-20" version="1">MKGKFNRTIMTLVGLLVIASMLFGCVPATQAPAAEDTTAAPAAGEKIKVGLSFSDFATERWKNEEVLLRGLLEDLGYEVLSQEANHDVKAQNDQIDNMVSQGVKGLIVVAEDGDAVVTSVEKAADAGVKVIAYDRLIKTPKIAAYLSFNNVEVGRQQADGVMKAIDIENWDVAANGKVRLVKLGGSPTDNNAILFRKGQDEILAKYEDKIEVVADQWVDNWDAANALKLMENILTAAGNDIDAVVASNDGTALGALQAMKAQGLAGVVPISGQDATADGSNSIVRGELTVSILKDIRNLSPLAVETLDTLLKGGTVPGMANYTMAELTNDPAYQGEVPCLFLEVQQVNKDNLYDLVVKSGFQPYDDVYRDIPDDQKPPKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y0U6</accession>
    <name>A0A0P6Y0U6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">dTDP-glucose 4,6-dehydratase</fullName>
            <ecNumber evidence="4 5">4.2.1.46</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_06530</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>dTDP-alpha-D-glucose = dTDP-4-dehydro-6-deoxy-alpha-D-glucose + H2O</text>
            <dbReference type="Rhea" id="RHEA:17221"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57477"/>
            <dbReference type="ChEBI" id="CHEBI:57649"/>
            <dbReference type="EC" id="4.2.1.46"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 5">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the NAD(P)-dependent epimerase/dehydratase family. dTDP-glucose dehydratase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.46" evidence="4 5"/>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062156.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06530"/>
    <dbReference type="EnsemblBacteria" id="KPL78859">
        <property type="protein sequence ID" value="KPL78859"/>
        <property type="gene ID" value="ADN00_06530"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1810"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008460">
        <property type="term" value="F:dTDP-glucose 4,6-dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009225">
        <property type="term" value="P:nucleotide-sugar metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05246">
        <property type="entry name" value="dTDP_GD_SDR_e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005888">
        <property type="entry name" value="dTDP_Gluc_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01181">
        <property type="entry name" value="dTDP_gluc_dehyt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="6">
        <location>
            <begin position="5"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL78859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="360" mass="40677" checksum="B3D8CAEE3B3038BC" modified="2016-01-20" version="1">MKNILVTGGAGFIGSNFVRFLLEKEPDVHVYNFDLLTYAGSLENLKNLPSPTRHTFIHGDIGDADLLDRIFSEHAIDTVVHFAAESHVDRSILGPEAFIQTNIIGTFKLLQTARKHWLTGASTLDGYRFHHVSTDEVFGSLAPQDPAFEETTPYSPNSPYSASKASSDHLVRAYFHTYGLPVSLTNCSNNYGPYQFPEKFVPLMIFNAMMGKPLPVYGDGQQIRDWLYVEDHCEAIWRVLKFGKVGETYNIGGNNQPTNLEVLDSICAILDERLPQSPFRPHASLKTFVKDRPGHDRRYAINITKVNTELGWAPRHNLKAGLEATIDWYLNNTAWLQAISKNDEFQNWLDNNYEKRGGNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y229</accession>
    <name>A0A0P6Y229_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Putative manganese efflux pump MntP</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">mntP</name>
        <name evidence="9" type="ORF">ADN00_03745</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Probably functions as a manganese efflux pump.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the MntP (TC 9.B.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061624.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03745"/>
    <dbReference type="EnsemblBacteria" id="KPL79014">
        <property type="protein sequence ID" value="KPL79014"/>
        <property type="gene ID" value="ADN00_03745"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.101"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005384">
        <property type="term" value="F:manganese ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01521">
        <property type="entry name" value="MntP_pump"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003810">
        <property type="entry name" value="Mntp/YtaF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022929">
        <property type="entry name" value="Put_MntP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35529">
        <property type="entry name" value="PTHR35529"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02659">
        <property type="entry name" value="Mntp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="7 8" id="KW-0464">Manganese</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="61"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="103"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="164"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01521"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL79014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="188" mass="19633" checksum="50DA4891C0081165" modified="2016-01-20" version="1">MELAAVVVIAVGLAMDCFAVSLGIGSSGNRQTARSIFRVSFHFGLFQGGMAFLGWLAGSTIVQFISSFDHWIAFILLAWVGVRMVREGINPELSDCQADRTRGGTLIVLCLATSLDALAIGLTLSLTNTPIAPASLVIGLASLLLSVIGILAGSGLGVRFGKRMVIAGGILLTLIGLRILLSHLNIIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y666</accession>
    <name>A0A0P6Y666_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10135</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77068">
        <property type="protein sequence ID" value="KPL77068"/>
        <property type="gene ID" value="ADN00_10135"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025495">
        <property type="entry name" value="DUF4386"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14329">
        <property type="entry name" value="DUF4386"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="203"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="233" mass="24825" checksum="4776C89D92D15968" modified="2016-01-20" version="1">MLPPSAAARPHWNGIYRIGAVAALAMLAIMAAQIGIYIAWPPPDSVSGFFALFQSNWLLGLLSMDLLYILNNTLLVLIYLALYAALKPAGDTAVLIALVLGLIGITAYYASNTAFEMLSLSRQYAAAASETQRVIALAAGEAMLATYKGTVFDTYYILNGISLLIFAAVMLRSPLFSRATAIIGLAAGVLMSIPSTAGTLGLVFSLLSLIPWAVFCILLIKPFFQLEAKIAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YA87</accession>
    <name>A0A0P6YA87_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_05735</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062011.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78741">
        <property type="protein sequence ID" value="KPL78741"/>
        <property type="gene ID" value="ADN00_05735"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1623"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="173"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="227"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="285"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="80"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL78741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="317" mass="35190" checksum="D237A1D023A7D723" modified="2016-01-20" version="1">MNQKKSSFVFNRLAIYLLLVVMAAFFLMPIYMLLITGIKSYQDVGLASMWKMPTSFSLESFGRAWAGSVSQGFRGLQGNFLNSIWLTVPAALLSAFIGSINGYIFSKWKFKGSDVLFSMLLFGMFIPYQSVLIPLVRVLQWLTQFTGPIIGFINSWKIAGSLSWLPGWLAGFIPAYGTIGGLIMVHVIYGVPIATLIFRNYYTEIPTELVEAGMVDGASLLGIYRHILFPISMPGFVVVLIWQFTSIWNDFLFGVIVTSNPNVQPVTVALNNLAGSYIVEWNVQMAGSLIAALPTMLIYVFLSRYFIRGLMAGSLKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YAT6</accession>
    <name>A0A0P6YAT6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_03750</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the bacterial solute-binding protein 9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061625.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03750"/>
    <dbReference type="EnsemblBacteria" id="KPL79015">
        <property type="protein sequence ID" value="KPL79015"/>
        <property type="gene ID" value="ADN00_03750"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.102"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030001">
        <property type="term" value="P:metal ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006128">
        <property type="entry name" value="Lipoprotein_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006127">
        <property type="entry name" value="ZnuA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01297">
        <property type="entry name" value="ZnuA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00690">
        <property type="entry name" value="ADHESNFAMILY"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0732">Signal</keyword>
    <keyword evidence="1 3" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133480" evidence="5">
        <location>
            <begin position="23"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="127"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="127"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL79015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="303" mass="33570" checksum="2E1A47F246BF4580" modified="2016-01-20" version="1">MKTRWLILTVAVLISLAGCAPAPDSAPAPLESNTLQVTVSIPPQKYFVERIGGERVTVNVMVEPGSDPHTYEPSPAQMKLLANSQVYFAVGVDFEQSWLERFQGANPQMRVVNTIEGLDLMEMATHAHEGEEHEEEDEAHASELDTHTWTSPEMVLRQAEKIYQTLAEADSAHASEYQANYEAFSIEISALQDEIRQTLEGVSSRKFLVFHPAWGYFAREFGLEQIAVEAGGQEPSAQELAAIVNEAKAENIRVVFAQPELSTRSAEVIAAEIGGEVLLISPLEENWMENMRKVAGVFEEVLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YBW5</accession>
    <name>A0A0P6YBW5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_02665</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000012">
        <property type="protein sequence ID" value="KPL79436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061415.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000012.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02665"/>
    <dbReference type="EnsemblBacteria" id="KPL79436">
        <property type="protein sequence ID" value="KPL79436"/>
        <property type="gene ID" value="ADN00_02665"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004107">
        <property type="entry name" value="Integrase_SAM-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13495">
        <property type="entry name" value="Phage_int_SAM_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="5">
        <location>
            <begin position="8"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="4">
        <location>
            <begin position="128"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL79436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="337" mass="38279" checksum="16C6ACDB13DCB154" modified="2016-01-20" version="1">MNRNPSGLLFSLCIDGFVKYKTAEGLSQRTVDSYEWVLRKWMEKIGDQPIGKITSADVLDYMTYLRTEYVPHTFAKPNPAHDAPTRKLSPKTLRNHWITFKAFFGWAVAEFKIKNPMEGIPGPRYKEAPVAAFTQEDLAALLKACVYSREYNPINRHNFVTRRPSAKRDEAMILFLLDTGLRASELCSLKIGELDLRTGKVVIKHGDEGGAKGGKGRTVFIGKSTRRAVWRYLADREDRDDPESPVFINRGNHPFNSNSLRHLIVRLADKAGVKGAHPHKFRHTFAITYLRSGGDVFTLQALLGHSSLDMVRHYAQIAEMDIERVHRKASPVDNLRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YCE0</accession>
    <name>A0A0P6YCE0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ribonuclease Z</fullName>
            <shortName evidence="8">RNase Z</shortName>
            <ecNumber evidence="8">3.1.26.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">tRNA 3 endonuclease</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">tRNase Z</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rnz</name>
        <name evidence="10" type="ORF">ADN00_02440</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Zinc phosphodiesterase, which displays some tRNA 3'-processing endonuclease activity. Probably involved in tRNA maturation, by removing a 3'-trailer from precursor tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>Endonucleolytic cleavage of RNA, removing extra 3' nucleotides from tRNA precursor, generating 3' termini of tRNAs. A 3'-hydroxy group is left at the tRNA terminus and a 5'-phosphoryl group is left at the trailer molecule.</text>
            <dbReference type="EC" id="3.1.26.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="8">Binds 2 Zn(2+) ions.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1 8">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the RNase Z family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.11" evidence="8"/>
    <dbReference type="EMBL" id="LGCL01000010">
        <property type="protein sequence ID" value="KPL79673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061367.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000010.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02440"/>
    <dbReference type="EnsemblBacteria" id="KPL79673">
        <property type="protein sequence ID" value="KPL79673"/>
        <property type="gene ID" value="ADN00_02440"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2706"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042781">
        <property type="term" value="F:3'-tRNA processing endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07717">
        <property type="entry name" value="RNaseZ_ZiPD-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01818">
        <property type="entry name" value="RNase_Z_BN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013471">
        <property type="entry name" value="RNase_Z/BN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 8" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="7 8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Lactamase_B" evidence="9">
        <location>
            <begin position="30"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="domain" description="Lactamase_B" evidence="9">
        <location>
            <begin position="202"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="66"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="141"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="212"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="270"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF12706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL79673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="311" mass="35076" checksum="82FB879EA92986A5" modified="2016-01-20" version="1">MFEVIFLGTSASAPSIQRGLPAQVIKHDEYRFLVDCGEGTQRQILQAGLGFKRLNRILITHGHLDHILGLAGLISTLMRWETMEGLEIYAGKRALERIHDLVYGVVLRNTRPPMPIDLIEVNEGPFFEADDFRISAFPVFHRGTDSFGYLFEEKGRRPFLPEKAEALNIPPGPWRRKLVEGEAASLPDGRVIDPETVLGEFKPGTRLVLVGDVGDTRSLLDVCRGADAIVMESTYLDEEENMARRFSHMTARHAAELARDAEARQLILTHISRRYRNRDVIKEAQSVFPAAVVARDFDIFQIKKDESPAQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YDI2</accession>
    <name>A0A0P6YDI2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_01995</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000007">
        <property type="protein sequence ID" value="KPL80067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80067">
        <property type="protein sequence ID" value="KPL80067"/>
        <property type="gene ID" value="ADN00_01995"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL80067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="109" mass="12449" checksum="99C8CC450538987A" modified="2016-01-20" version="1">MAKAGKVPLDRAAKFLYIDERQDDQPSDGRCSVSIYLLDDSLKVDIYFDPDDTSFEDDICVCFTESCDEEEKIFKVDESHIYITPQQARQLAEALLKAADRSDYSDTNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GKX1</accession>
    <name>A0A0N8GKX1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CxxC_CXXC_SSSS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_17710</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000043">
        <property type="protein sequence ID" value="KPL70882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064382.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000043.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70882">
        <property type="protein sequence ID" value="KPL70882"/>
        <property type="gene ID" value="ADN00_17710"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013429">
        <property type="entry name" value="Regulatory_FmdB_Zinc_ribbon"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09723">
        <property type="entry name" value="Zn-ribbon_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00834">
        <property type="entry name" value="CxxC_CXXC_SSSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02605">
        <property type="entry name" value="CxxC_CxxC_SSSS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CxxC_CXXC_SSSS" evidence="2">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="50"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00834"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL70882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="70" mass="7858" checksum="720F33AEFDD1FEF9" modified="2016-01-20" version="1">MPLYRYQCEECLYEFEKLVSYSDSDKLPQCPNCESNATHKQVTSFSSFGFYSPNSSSNSGSCGGSSSRFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GKX2</accession>
    <name>A0A0N8GKX2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Translation initiation factor IF-1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">infA</name>
        <name evidence="5" type="ORF">ADN00_17755</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">One of the essential components for the initiation of protein synthesis. Stabilizes the binding of IF-2 and IF-3 on the 30S subunit to which N-formylmethionyl-tRNA(fMet) subsequently binds. Helps modulate mRNA selection, yielding the 30S pre-initiation complex (PIC). Upon addition of the 50S ribosomal subunit IF-1, IF-2 and IF-3 are released leaving the mature 70S translation initiation complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Component of the 30S ribosomal translation pre-initiation complex which assembles on the 30S ribosome in the order IF-2 and IF-3, IF-1 and N-formylmethionyl-tRNA(fMet); mRNA recruitment can occur at any time during PIC assembly.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the IF-1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000043">
        <property type="protein sequence ID" value="KPL70890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064391.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000043.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17755"/>
    <dbReference type="EnsemblBacteria" id="KPL70890">
        <property type="protein sequence ID" value="KPL70890"/>
        <property type="gene ID" value="ADN00_17755"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2143"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04451">
        <property type="entry name" value="S1_IF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00075">
        <property type="entry name" value="IF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006196">
        <property type="entry name" value="RNA-binding_domain_S1_IF1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022967">
        <property type="entry name" value="S1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004368">
        <property type="entry name" value="TIF_IF1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33370">
        <property type="entry name" value="PTHR33370"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01176">
        <property type="entry name" value="eIF-1a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00008">
        <property type="entry name" value="infA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50832">
        <property type="entry name" value="S1_IF1_TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2 3" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="2 3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="S1-like" evidence="4">
        <location>
            <begin position="1"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL70890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="83" mass="9659" checksum="FDAEF42EF0BFDD26" modified="2016-01-20" version="1">MPKEEDKVLVEGTIVEALPGTQFKVRLDNDHEVLAYLSGRMRKYYIRILLGDRVRVEMSPYDLTRGRIVYRQKKGSSQFVGLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GKX4</accession>
    <name>A0A0N8GKX4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Band 7 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_17900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000043">
        <property type="protein sequence ID" value="KPL70906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064409.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000043.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70906">
        <property type="protein sequence ID" value="KPL70906"/>
        <property type="gene ID" value="ADN00_17900"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2162"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PHB" evidence="1">
        <location>
            <begin position="26"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="326" mass="35992" checksum="C9E9127CAA4AC633" modified="2016-01-20" version="1">MSVLIGIIVGFGAWFVLRYVLTAFYTVDQNERAVKTIFGRAERLGDTMTADSALGETLTDEHKQRYNYPMVRVIPPGGPYLKWPWERIYKVSVATQTINMAYDPDDPNANSRGTLLEAVTKDQLNTGLTGQIRYRVAESNLYAYLFGVKQPISHVMGYFVSVLRERIASFEAPPPAPNAEGEISNVSGVSINDLRKNLRDLNEHMERECATSAARYGIILDASLITGIDPPAEVEVALAAINTAHNQVSSDISLAQAAADQKIVQSKRAVEIETLNAQAEVEPLVALADQLQALKKSGKGALQSYLRNVRLRLFDHAENIVREVES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GL37</accession>
    <name>A0A0N8GL37_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_17105</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064266.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL71410">
        <property type="protein sequence ID" value="KPL71410"/>
        <property type="gene ID" value="ADN00_17105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL71410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="450" mass="48814" checksum="B2AA0E249B60B090" modified="2016-01-20" version="1">MYISGPNLPSQTTTPLDNSEVNLRANQQIEAQVLRVNGQQVVISVQGVPVVARMTSAEQAAVLVEHRLARFIVQDVDNKTLVLQLVSADANTQQAPAVRIAPADLTATLLDQAGIALTQSNLAAARAALGQGLLLTPALIHELTQALEQLPKWTEQDARIAAALKAAGLPITPESIRLAQSTPAALLESFNNLAQQLRGLLSRSGLPQDLYQQALRAEASLRSLILQAGSPEELQQALKDITSRLGKSLENSLLCQINQTANGESALSELSRLRAMLGQSRFALTESLDRFMETVRWNHFMNIPENGPLQRAIWTGVDIPILLPAHPQGQPDQNQLSSLHIRVAGDPDADHLAVNPAYTRLVIQTELPGGEILSVDLSMVHHQVNAEVTSTDTEVGEIAEELLPTLQDGLSHHGFQIVSSSFKIKHNASGEEIKRFHPLNLRLKPVNLKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GLC0</accession>
    <name>A0A0N8GLC0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PS_pyruv_trans domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_16505</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064142.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16505"/>
    <dbReference type="EnsemblBacteria" id="KPL72074">
        <property type="protein sequence ID" value="KPL72074"/>
        <property type="gene ID" value="ADN00_16505"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007345">
        <property type="entry name" value="Polysacch_pyruvyl_Trfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04230">
        <property type="entry name" value="PS_pyruv_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PS_pyruv_trans" evidence="1">
        <location>
            <begin position="14"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="390" mass="42976" checksum="FEC06E3C6FCE2CA3" modified="2016-01-20" version="1">MKRLAICGEIYSANVGDRAIHDSLHYLLKRLDPSIEIIPIDLSGRISSSGATERVGLNQRVALLAALPIFYPALMMLNIASQQVKRLRGQRSQWRQRLETADLLVVGGGQLLMDDALNFPLKISSLIHVAQSLNLPFSFSACGVGSNHTWLGRRLLCDALVGAQSISLRDHLSQNRLKMLCPGLASQVTMDPAIWAGDVYPFAPAGRNTGCIGLGVINRNEANLHLPREQRFSKHAWDQLWIDLVGELAANNRQVELFTTGSPVDDLFAQALFAHAQGRGWAQVSLATRPVNPQQLLTSLRDYSVVVAARLHAAILANAIGISTIGLSWDTKVQTYYSESDRPELCFDLNQLSIQQVSQAVLETRGQPFPREKLEELKQRALTNAHLILG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GLE7</accession>
    <name>A0A0N8GLE7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Exonuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_15135</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15135"/>
    <dbReference type="EnsemblBacteria" id="KPL72290">
        <property type="protein sequence ID" value="KPL72290"/>
        <property type="gene ID" value="ADN00_15135"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Exonuclease_RNaseT/DNA_pol3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exonuclease" evidence="1">
        <location>
            <begin position="9"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="178" mass="20859" checksum="D67AEB3CA773B4C7" modified="2016-01-20" version="1">MARKVQQIKPVYIDTETTGLDRQAEIIEIAVIDHDGAILMDELIRPLRSIPFDAMQVHHITNEMVAGARSWPVLWQDLRPLLHGRLLAFYNEEFDMRMIRQTHEQYTPWKENFNTFCVMKLYAQFRGEWDPRRRGYRYFRLEEAGRAAGIPLPNSHRAADDTLLTRALLDYIAATPMT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMH4</accession>
    <name>A0A0N8GMH4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13015</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000028">
        <property type="protein sequence ID" value="KPL75306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063456.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000028.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL75306">
        <property type="protein sequence ID" value="KPL75306"/>
        <property type="gene ID" value="ADN00_13015"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="302"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="333"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="365"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="396"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="438"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="477"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL75306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="507" mass="57871" checksum="646F4776FE7F9E4F" modified="2016-01-20" version="1">MEKALNIPEFGLQPQPTNEHFNQDSWEQIKNKFQLDTSVYCWQFKWQGTMITPVSLGNLSIKEHLLRKLCSNSQSAYYEDAGARLLDAAKTPALQKNTKLLSPSIHKLLFFSPFLLETWYENENWLPDHKKGKNPLEFGLILYRLSEIFLSALAIQAHRQVGDLPEDLLLARILLIRLRFRLLAGLSQFSKLAAYLPDFALIVRNAQREYARLILERTDEVELALQLAIPPQSGWDLDEEINLILFSDDGQSRLWPFAQETPSDRLFTDTIIRAWMLPHDNLQGATASLVSLLHPNANHPSLINCLILSLRTLIFLSAASFILFLFFQNKYFLALPFIASGGGVIGLARLVFTRKLIIRQRTYPLALRIPAMGMVGLLIAAEFIEDLAKKMDHSSQNLTGLFISLSAVSLLFAYLYITSEISARLRFSQFKIQRALDLFSYGWAATFWLSTLAFFVYWRINNPETALLKFFSYPSLWLILLVLSSASLLVGVFTQIFWEDKAIAEPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMK1</accession>
    <name>A0A0N8GMK1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Resolvase/invertase-type recombinase catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_12830</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063417.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000027.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12830"/>
    <dbReference type="EnsemblBacteria" id="KPL75522">
        <property type="protein sequence ID" value="KPL75522"/>
        <property type="gene ID" value="ADN00_12830"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1390">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1750.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038109">
        <property type="entry name" value="DNA_bind_recomb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011109">
        <property type="entry name" value="DNA_bind_recombinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006119">
        <property type="entry name" value="Resolv_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036162">
        <property type="entry name" value="Resolvase-like_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07508">
        <property type="entry name" value="Recombinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00239">
        <property type="entry name" value="Resolvase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00857">
        <property type="entry name" value="Resolvase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53041">
        <property type="entry name" value="SSF53041"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51736">
        <property type="entry name" value="RECOMBINASES_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Resolvase/invertase-type recombinase catalytic" evidence="2">
        <location>
            <begin position="30"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="305"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51736"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL75522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="597" mass="68244" checksum="D70E3A06E261E737" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMR4</accession>
    <name>A0A0N8GMR4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ADN00_11740</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11740"/>
    <dbReference type="EnsemblBacteria" id="KPL76026">
        <property type="protein sequence ID" value="KPL76026"/>
        <property type="gene ID" value="ADN00_11740"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="35"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="76"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="154"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="178"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="290"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="36"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="353"/>
            <end position="588"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="386"/>
            <end position="393"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL76026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="604" mass="67932" checksum="971BEA18B2E3CD92" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GN18</accession>
    <name>A0A0N8GN18_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062793.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76858">
        <property type="protein sequence ID" value="KPL76858"/>
        <property type="gene ID" value="ADN00_09650"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="13"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="171" mass="19445" checksum="EF53FEC2FDC36DE5" modified="2016-01-20" version="1">MNPIPQAPCPTGYEIRSLGDEREHPARSWCSWRAFHNDEPVSQYDGDFSWYRNLQSAPLYRRDLDLVAATPNGDIAAFCVIYYDDTTRSAVTVQVGVAAEHWRRGLGKAILYEGMRRLQRLGCTRVFATANDIPADALYYSVMTEMKVSDTWVKLFEKNISLQEKVSDDVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GN24</accession>
    <name>A0A0N8GN24_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_09920</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76906.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062843.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09920"/>
    <dbReference type="EnsemblBacteria" id="KPL76906">
        <property type="protein sequence ID" value="KPL76906"/>
        <property type="gene ID" value="ADN00_09920"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76906.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="123" mass="13953" checksum="C6A4E1B973D9A52F" modified="2016-01-20" version="1">MTLKTEFEFELPMGYVDKEGNLHKKGTMRLATAMDEITILNDMRVQSNEAYIVIVLLARVITSLGSVSHITTNVIENLFAADLTFLQEFYRQINETGHTRREYTCPHCQKPIEVDLSTLGGQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GN72</accession>
    <name>A0A0N8GN72_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Amino_oxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062691.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09150"/>
    <dbReference type="EnsemblBacteria" id="KPL77290">
        <property type="protein sequence ID" value="KPL77290"/>
        <property type="gene ID" value="ADN00_09150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amino_oxidase" evidence="1">
        <location>
            <begin position="13"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="504" mass="56944" checksum="649B466301B91124" modified="2016-01-20" version="1">MQKNSMIIIGAGFAGLSAGIYAQMNGYSTQIFELHTLPGGLCTAWKRKGYTVDGCIHWLVGSSPESAMNQFWREVGLAQGREFINLDEFLRYEGSDGRTVVFYSDVDRLEKHLLDLSPKDEPVIREFISGIRMGIRFDQQPTERDSGITKLIKGIKMGWLFLTRGKDMRRWMDTTAEQFANRFQDPLLREAFKEIWYPEFSIFFIMFTFSYLHNHNAGYPIGGSMPLSRALEKRYLELGGQIHYGKKVEKVLVENDRAVGIELADGSQHRAGRVVSAADGHATIFKMLDGKYADEKIKEPYEKWPIFPPLVYVGLGVNNRFENEPKTVSGISFALKQPVEIADQTLERLSVHVYNQDPTLAPDGKTSLTVMIPSSYAYWKEMAKDPVEYEEKKEQIARQVVAMLEQRFPGIGSQVEMVDVATPLTFERYTGNWQGSFEGWLITPQNAGSIMSPMKQTLPGLSNFYLCGQWVEPGGGLPTGVMSARRLLKAVCKEDGRKFITTQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNI8</accession>
    <name>A0A0N8GNI8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">PMT_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">ADN00_06970</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062262.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06970"/>
    <dbReference type="EnsemblBacteria" id="KPL78218">
        <property type="protein sequence ID" value="KPL78218"/>
        <property type="gene ID" value="ADN00_06970"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3210"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019962">
        <property type="entry name" value="CHP03663"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001258">
        <property type="entry name" value="NHL_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038731">
        <property type="entry name" value="RgtA/B/C-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41710">
        <property type="entry name" value="PTHR41710"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01436">
        <property type="entry name" value="NHL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13231">
        <property type="entry name" value="PMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51125">
        <property type="entry name" value="NHL"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="23"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="151"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="174"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="195"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="225"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="266"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="302"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="341"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="371"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="413"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="490"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="516"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="550"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="592"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="622"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="domain" description="PMT_2" evidence="11">
        <location>
            <begin position="77"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="repeat" description="NHL" evidence="9">
        <location>
            <begin position="847"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="repeat" description="NHL" evidence="9">
        <location>
            <begin position="914"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="repeat" description="NHL" evidence="9">
        <location>
            <begin position="965"/>
            <end position="993"/>
        </location>
    </feature>
    <feature type="repeat" description="NHL" evidence="9">
        <location>
            <begin position="1008"/>
            <end position="1041"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF13231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KPL78218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="1141" mass="127258" checksum="1A902D8FC3781D9A" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNJ3</accession>
    <name>A0A0N8GNJ3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF218 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_07250</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062314.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78258">
        <property type="protein sequence ID" value="KPL78258"/>
        <property type="gene ID" value="ADN00_07250"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06259">
        <property type="entry name" value="YdcF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003848">
        <property type="entry name" value="DUF218"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02698">
        <property type="entry name" value="DUF218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="DUF218" evidence="2">
        <location>
            <begin position="55"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="217" mass="23986" checksum="7EA2B7DADF0F04A3" modified="2016-01-20" version="1">MHPTPPAKGNGSAKSCFKLVGTGSLLLALPFLIYAVLWAAGALLVVADPQKKVDAAVALSGGELDRISEAARLYTDQTVRWVIITDTGEELPQLGSDYTTLLKNEARKLGVPEDAILVTEKQVASTIDEAAAVRQLLQKNDFDSCIVITDPFHTFRTRLKFRQAFDETGLTVRVRPVRGHWYHATTWMFSARGWQATVTEYIKIFGYALGFTDNILQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WMH0</accession>
    <name>A0A0P6WMH0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA mismatch repair protein MutS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_18050</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL69975.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064441.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18050"/>
    <dbReference type="EnsemblBacteria" id="KPL69975">
        <property type="protein sequence ID" value="KPL69975"/>
        <property type="gene ID" value="ADN00_18050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2911"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS_family"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="PTHR11361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_MISMATCH_REPAIR_2" evidence="3">
        <location>
            <begin position="324"/>
            <end position="502"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL69975.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="503" mass="57465" checksum="53E7B9DBF4A3BA1E" modified="2016-01-20" version="1">MKAYLMFNDRDFDLKGPQRTNQDFLVQDLELDFLFNAMAGGDKYLLEVATKALLSDAPMTVERVLYRQAILKDCLKNPSIVREIYHIALDAIEKEKKAYFGFFCKFPDSILSRSIEVLQLFSDTLKRLRAISETYGAQFDSQGFQTLFAMLQRELSDAYFLEIQNHLRVLKFRDGVWISAELGQANKGINYVLRKPPENHSNWFDRLFTIQPPEFSYTIADRDEAGSRALSELRERGINLVANALAQSCDHILNFLVLLRTELAFYLGCMNLYEQLGQMGEPATFPVPARSEERELCFEGLYDMCLALNLQQKVIGNDLEADRKDLLIITGANQGGKSTFLRSIGLAQLMMQNGMFVPAISYRANLCEGLFTHFKREEDTTMKSGKLDEELSRMNTIAGHLAEHSMVLFNESFAATNEREGSEIARQIVRALVERKVKVFFVTHLFDFAQSMFEEGSLTSIFLRADRQTDGGRTFKLYEGEPLQTSFGLDVYQRVFASRADRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WR81</accession>
    <name>A0A0P6WR81_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_17110</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064267.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17110"/>
    <dbReference type="EnsemblBacteria" id="KPL71411">
        <property type="protein sequence ID" value="KPL71411"/>
        <property type="gene ID" value="ADN00_17110"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.484"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1690.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006135">
        <property type="entry name" value="T3SS_substrate_exporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029025">
        <property type="entry name" value="T3SS_substrate_exporter_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30531">
        <property type="entry name" value="PTHR30531"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01312">
        <property type="entry name" value="Bac_export_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00950">
        <property type="entry name" value="TYPE3IMSPROT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160544">
        <property type="entry name" value="SSF160544"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL71411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="100" mass="10994" checksum="F2B89C135E1D17F3" modified="2016-01-20" version="1">MHPRLVYLKQQQQQRAAALGYNPESDEAPKVLASGKGLMAEKIIAIAKEKGIPIKEDPLLAAALAEVDIGATIPPELYAVVAEVIAYVYRIQNQKLKRKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WST9</accession>
    <name>A0A0P6WST9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_16575</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064155.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72087">
        <property type="protein sequence ID" value="KPL72087"/>
        <property type="gene ID" value="ADN00_16575"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="78"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="110"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="146"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="190"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="249"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="72"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL72087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="284" mass="31563" checksum="6BE580FE62B6A458" modified="2016-01-20" version="1">MNLSRIIFALIFTFFITGVLFPFYWMVSSSFKSYAEIGGRNPVYVPSALRLDAYKELFDPAHKSFQNFGTNIMNSVKVSVPAAILTVILSTLGAYAVARLNFRGKNLMVNGILLIYLFPGVLLIIPLFAMLAQVSTQLGFDVQDNLSVLILTYLAQTLPVGLYMLANYFRTIPSEIEQAGLIDGCSRLQVIWKITLPLAIPALVSVFIYTFMIAWNEFLYAFIFLNSNDLFTIPIKISAIFGDPTPRPHVVMAASTIMTLPIIVLFLAMERYLEQGLVSGGVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WW17</accession>
    <name>A0A0P6WW17_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Bac_transf domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_18520</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial sugar transferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18520"/>
    <dbReference type="EnsemblBacteria" id="KPL70169">
        <property type="protein sequence ID" value="KPL70169"/>
        <property type="gene ID" value="ADN00_18520"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003362">
        <property type="entry name" value="Bact_transf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017475">
        <property type="entry name" value="EPS_sugar_tfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02397">
        <property type="entry name" value="Bac_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03025">
        <property type="entry name" value="EPS_sugtrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="62"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="122"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="291"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="Bac_transf" evidence="8">
        <location>
            <begin position="286"/>
            <end position="469"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL70169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="474" mass="54015" checksum="1D7A49740089D23A" modified="2016-01-20" version="1">MESGKGKPKPIFWRLRPSERQAILLIGDMLVGFLALAISIVIWSQEDWLRLSFSFLTERTPAWFFLAPFIWMLLTIELYDVRRASRRSETLKGVAIAAGVSLGLYLLFYFTSEPNSLPRRGVSVFILAVSLLILMWRFIYIRVFTAPVFMRRVLIIGAGRSGENLVQVIDSIWPLPFYLVGLIDDDPAKQNMKYGNHPVLGSSQQLLEIIERERITDLVFAISGEMNPAMFQAVLTAEERGVEVTTMPLVYEELLGRVPILLLQSDWILRSFVDQAHTNNFFEMAKRLMDIIGGLIGCIGLALLYPFIAVLILLDDGAPVLYSQERLGKNGKPYQIIKFRTMVKDAEKDGKARVAVKNDSRVTRVGRLLRKSHLDELPQFWSVLRGEMSLVGPRAERVELVNSLQTKVPFYRARLFVKPGLTGWAQVNYGYAETVEDTIVKLEYDLYYIKHRNLMLDLLIIFRTAGTVFGLRGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZ42</accession>
    <name>A0A0P6WZ42_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_16180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064081.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72025">
        <property type="protein sequence ID" value="KPL72025"/>
        <property type="gene ID" value="ADN00_16180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="244"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="307"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="340"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="373"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="458"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="494" mass="57221" checksum="1F9310377630DA91" modified="2016-01-20" version="1">MALFQSISTHFVEFLVTPDQKKFKLANQIFMALLFFGGIAVWGLFLYCPQNTCNYHDWLDIIAPRLNFLKESVTVGAWPLHASTPMKLGVFYTQRYLAIPDAFVSPQFLLLRFLNVYQFIVFEMVLFYTLGFWGLRRIGQKLGFSNLVFTFVFILFNFNGHIVAHISVGHFTWVAYFLFPWFALLVFQLIDGQSGWRWIAKMASLLFFTLLQGGYHHFVWMLFFLGFLAIFIPRHFFTILKTAVFSVLLGMFRFLPLLALYNSLNDNQFMGGYPDLQSILENMVIIRQGGVEIPINNLTLPLGTWEMTAYVGVIGAFFILFFGLIYPIYKSNPEYPYRVLLFPTIGLLMLSFDRVFHLLFTRIPLPIFTGERVVTRILGLVLVFVLIQAGSEFQHWLNHHTLSRFSMLSILSLAVVAGHDLARNFREWMLLVASHYFPGEAKIEPIWLVDNNYTDQPYLNLILIGSAVMLVSYSVLIALLWWERKQDRKTKTAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZ94</accession>
    <name>A0A0P6WZ94_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_16655</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064168.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72099">
        <property type="protein sequence ID" value="KPL72099"/>
        <property type="gene ID" value="ADN00_16655"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132733" evidence="1">
        <location>
            <begin position="27"/>
            <end position="490"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="490" mass="51857" checksum="45BE53ABCF9227E6" modified="2016-01-20" version="1">MKRMTGILFIAFLAGLVFSPIQPAKASPTHTSIWSSSIVVYNPSDTDTTEYNIVYYGSDDPNNVIPSSLRTLIPHESVSILVGSTILDENFKGGAVISSDREVIAIYRQSTPETSMIVYSSFTIDDAGVGKFYIPVARRNADGYSSRISVQNLHTAPASVSFQFFSNSGTYSQTITPAANQVYSNASLVFDLASTDFNALGDNFIGSVVITTGGSEKIIAAVQDFAGDSSQTYAYQGEAAGDNEVFIPNAACNFGRSQLSTELLVQNTGSGTLSSFSIEYFDANGTLSGAHSNLSGLNLAPGDSISVDSCSAIAAGSNYSALVTSSQQPVSVVVRTTDNSGFAATINGFSQPGSEWLGSDNKYRMVLPYGEWTRSDNSYQTYIAVMNASDSAATEVNAVYFYENGTRAVTHTLASASNPLPVKAKRTTNANAAPGLLNPQDQYFKGAVVIESNVPIVAVARVQRTLNNPAGGLITEGDDYGAIPYAKPAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X016</accession>
    <name>A0A0P6X016_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_12870</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063424.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000027.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12870"/>
    <dbReference type="EnsemblBacteria" id="KPL75528">
        <property type="protein sequence ID" value="KPL75528"/>
        <property type="gene ID" value="ADN00_12870"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007555">
        <property type="entry name" value="DUF499"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04465">
        <property type="entry name" value="DUF499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL75528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="1097" mass="121703" checksum="1BD60E90ABD3D46A" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X156</accession>
    <name>A0A0P6X156_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_12085</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063272.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12085"/>
    <dbReference type="EnsemblBacteria" id="KPL76077">
        <property type="protein sequence ID" value="KPL76077"/>
        <property type="gene ID" value="ADN00_12085"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3893"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03220">
        <property type="entry name" value="ABC_KpsT_Wzt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10147">
        <property type="entry name" value="Wzt_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015860">
        <property type="entry name" value="ABC_transpr_TagH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029439">
        <property type="entry name" value="Wzt_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14524">
        <property type="entry name" value="Wzt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="6"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="72"/>
            <end position="79"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL76077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="421" mass="47077" checksum="90F0611990E67166" modified="2016-01-20" version="1">MSNIAIRVENLGKKYRLGAPQLKYRTLRESLSDGFERATRRLRSGEQDPDVLWALRGVSFEVKQGEVLGIIGRNGAGKSTLLKILSRVTEPSEGYAEIRGRVGSLLEVGTGFHPELTGRENVYLNGAILGMHRDEIESKFDEIVAFSEMEKFIDTPVKRFSSGMQLRLAFAVAAHLEPEILVVDEVLAVGDAEFQRKCLGKMNDVAQAGRTVLFVSHNMSAVLRLTQEAMVIDKGNVVLRAPSTEAVDFYLSRGLSQEGERVWEADEVPDSAYPFRPMAVRVLNGQGQVKDTLRSTEPVQIEIEYEIEQAISGLRVGLYLMTVRGEYILTSFDTDDSGLFEQHAVRQPGHYTSRCVVPPDFLNEGRYALGINASSYRVKRYFQDDQAITFNVDAAGAPGMQWPEPRLGPVRPRFEWKIEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X163</accession>
    <name>A0A0P6X163_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Glyoxylate reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_12135</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063282.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12135"/>
    <dbReference type="EnsemblBacteria" id="KPL76086">
        <property type="protein sequence ID" value="KPL76086"/>
        <property type="gene ID" value="ADN00_12135"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3903"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006139">
        <property type="entry name" value="D-isomer_2_OHA_DH_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029753">
        <property type="entry name" value="D-isomer_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006140">
        <property type="entry name" value="D-isomer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00389">
        <property type="entry name" value="2-Hacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02826">
        <property type="entry name" value="2-Hacid_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00670">
        <property type="entry name" value="D_2_HYDROXYACID_DH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00671">
        <property type="entry name" value="D_2_HYDROXYACID_DH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2-Hacid_dh" evidence="3">
        <location>
            <begin position="4"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="domain" description="2-Hacid_dh_C" evidence="4">
        <location>
            <begin position="108"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL76086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="325" mass="34898" checksum="127DD581271A2E93" modified="2016-01-20" version="1">MNKVFVTRQIPDIGLELLARECQLDVWPGELPPSRAELIEHIQPADGLLCLLSDRIDEEILQHAPSLKVISNYAVGFDNIDVAAATRRGIPVGNTPGVLTHATADFAFALLMAAARRVPEADRSVRAGQWKTWGPKTLLGADLYQATLGLIGFGRIGQAVAQRARGFDMRVLVYDPSFNPSDLPAGVQSVALDVLLSQSDFISLHVPLTPQTHHLINARAFEQMKPTAILVNTARGAVVDTAALYHALKSGQIASAALDVTDPEPLPADHPLLGLENLVIAPHIASASTATRDKMAVMAAENLLAGLNQQPLPNCVNPHVYNDSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X194</accession>
    <name>A0A0P6X194_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_14995</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000036">
        <property type="protein sequence ID" value="KPL73092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063845.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000036.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL73092">
        <property type="protein sequence ID" value="KPL73092"/>
        <property type="gene ID" value="ADN00_14995"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1863"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01547">
        <property type="entry name" value="SBP_bac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132763" evidence="2">
        <location>
            <begin position="24"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL73092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="473" mass="51462" checksum="4C210151F3D78ED6" modified="2016-01-20" version="1">MKKSVWQLIAVLVVAAMVLAACAPGPVETEAPVEPTQAPAEPTKAPEQPAEAPTAEPVVEEPASFLEAAFAGEYSGTVVTMAGPFTDEDAVKFNAAVADFEEKTGIDIQYEGSKEFETTISIRVDGGDAPDIADFPQPGLLANFVRDGKVVDVSQFLDMEKLQANYNQSWLDMAMMESPDGEIMAGVWQRVNGKSLVWYPKDDFEVAGYEIPQTWDEMLALSDQIVADGDTPWCIGIESGTATGWPATDWMEEVMLRTTSLENYDKWVSGELKFSSPEVKAAAEKVGEIWLNDEYVYGGRASIVTTFFGDAPAPMFEDPAKCYFHKQGNFITSFFPAGVEAGVDYGFFYLPPIDEAYGKPVLVAGDIMAMFNDRPEVRAVMEFFTTGASVESWVRSGGAISPHLDSSLDWYSNDVDRGVAEIILNATSLRFDASDLMPGEVGAGSFWKGMTDWVSGTVDLDTALAEIDAAWPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X1E7</accession>
    <name>A0A0P6X1E7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_14905</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000036">
        <property type="protein sequence ID" value="KPL73077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063828.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000036.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL73077">
        <property type="protein sequence ID" value="KPL73077"/>
        <property type="gene ID" value="ADN00_14905"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007161">
        <property type="entry name" value="DUF364"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025251">
        <property type="entry name" value="DUF4213"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04016">
        <property type="entry name" value="DUF364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13938">
        <property type="entry name" value="DUF4213"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4213" evidence="2">
        <location>
            <begin position="4"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="DUF364" evidence="1">
        <location>
            <begin position="110"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL73077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="250" mass="27480" checksum="C6E8843FAD4D6FCD" modified="2016-01-20" version="1">MEAIRQLIQTLRPAEIDDVRIGLHWIGVTARAQGRLTCGLASTVPASHDHHSDFDVPEAGRLSLLSGLELAEWALSDHPIRTGIGLAAINAMVDPCPELWEDINAEQVILRYAEQGPVGLLGRFPFIPRLREKVKQLYVFELNPQPGEYGTDDMKTILPDCAVVAITGMTLVNHTFEKVISCRSPDSISLVMGPTTPVSPVLFDYGIDLISGTVVEKIEPVMRCLIQGGAYRQLHQAGTRLVTIQSPRLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X1X3</accession>
    <name>A0A0P6X1X3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_11025</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76497">
        <property type="protein sequence ID" value="KPL76497"/>
        <property type="gene ID" value="ADN00_11025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5012588088" evidence="2">
        <location>
            <begin position="16"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="81"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL76497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="293" mass="31519" checksum="CEA141E6B70B472C" modified="2016-01-20" version="1">MSGMVVLLLVMLACATTPTPTVDPGLEQTAVALGVMATQNAKNQATLQAASLPTAAPTVDTLATEQAAAQLQAATAAAQQAQAQTEAAAQAAEPTTQPPTEAPPPPDPAEARAAEMDSIIQQMKSKNWFKASEWEYHDAGSFEQTWYDTKTFDRWGTGIDGGNVVIYGEASWRFVGTAKEGEQSGCGFAYGEGDLDHWHASFLTMDGVVHTYRQRGGEFIEMKGGNYYGKMTDPTQIVVVVEDKMLSVFINGVEAVRFRDPYLQSGEVSFSVKTGSTRGFTCTIENAAVWELR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X1Y6</accession>
    <name>A0A0P6X1Y6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_11125</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063086.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11125"/>
    <dbReference type="EnsemblBacteria" id="KPL76516">
        <property type="protein sequence ID" value="KPL76516"/>
        <property type="gene ID" value="ADN00_11125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00037">
        <property type="entry name" value="Fer4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="7"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="37"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL76516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="73" mass="7803" checksum="6CFA1217C264282A" modified="2016-01-20" version="1">MRKSPSPHPEIDLSRCTGCGACIQVCPEQAIGKIGSLPRIMKPELCTLCALCEEVCPMGVISVPFVIGWAEAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X2C7</accession>
    <name>A0A0P6X2C7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">CRISPR-associated endoribonuclease Cas2</fullName>
            <ecNumber evidence="9">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">cas2</name>
        <name evidence="11" type="ORF">ADN00_14220</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer, forms a heterotetramer with a Cas1 homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 10">Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="9"/>
    <dbReference type="EMBL" id="LGCL01000034">
        <property type="protein sequence ID" value="KPL73723.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063694.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000034.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14220"/>
    <dbReference type="EnsemblBacteria" id="KPL73723">
        <property type="protein sequence ID" value="KPL73723"/>
        <property type="gene ID" value="ADN00_14220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043571">
        <property type="term" value="P:maintenance of CRISPR repeat elements"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09725">
        <property type="entry name" value="Cas2_I_II_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01471">
        <property type="entry name" value="Cas2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021127">
        <property type="entry name" value="CRISPR_associated_Cas2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019199">
        <property type="entry name" value="Virulence_VapD/CRISPR_Cas2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34405">
        <property type="entry name" value="PTHR34405"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09827">
        <property type="entry name" value="CRISPR_Cas2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF032582">
        <property type="entry name" value="Cas2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01573">
        <property type="entry name" value="cas2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 10" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="5 9 10" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6 9 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 9 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 9 10" id="KW-0540">Nuclease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <position position="14"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR032582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL73723.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="97" mass="10890" checksum="4B2DC3FC68AB760E" modified="2016-01-20" version="1">MKNDGRAFYVIAYDIADNKRRAKIAREMEALGARVQGSVFEAWLTPAELKKLTTRAAKVLKADEDSLRYYVICEACRAKIQTQGKAKTTPPPDLMIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X2V4</accession>
    <name>A0A0P6X2V4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_09705</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09705"/>
    <dbReference type="EnsemblBacteria" id="KPL77064">
        <property type="protein sequence ID" value="KPL77064"/>
        <property type="gene ID" value="ADN00_09705"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024227">
        <property type="entry name" value="DUF3795"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12675">
        <property type="entry name" value="DUF3795"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL77064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="118" mass="13701" checksum="E4FB9B7B522A5E56" modified="2016-01-20" version="1">MARSKGLLKEKHLKDGCKGCRAQDKKCAWVKRDCVLLRKHQIAFCFECPNFPCENLKKFDERHIREDQLSPIENLLRIKEVGARQWLAEQAEAWKCPQCGGNLCVIDRECYDCGYPCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X2W2</accession>
    <name>A0A0P6X2W2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Dipeptide epimerase</fullName>
            <ecNumber evidence="3">5.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_10850</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2 3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="2 3">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the mandelate racemase/muconate lactonizing enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10850"/>
    <dbReference type="EnsemblBacteria" id="KPL77083">
        <property type="protein sequence ID" value="KPL77083"/>
        <property type="gene ID" value="ADN00_10850"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2649"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016855">
        <property type="term" value="F:racemase and epimerase activity, acting on amino acids and derivatives"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009063">
        <property type="term" value="P:cellular amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03319">
        <property type="entry name" value="L-Ala-DL-Glu_epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034603">
        <property type="entry name" value="Dipeptide_epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029065">
        <property type="entry name" value="Enolase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018110">
        <property type="entry name" value="Mandel_Rmase/mucon_lact_enz_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013342">
        <property type="entry name" value="Mandelate_racemase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13378">
        <property type="entry name" value="MR_MLE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00922">
        <property type="entry name" value="MR_MLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="SSF51604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="SSF54826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00909">
        <property type="entry name" value="MR_MLE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2 3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MR_MLE" evidence="4">
        <location>
            <begin position="120"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; specific for (R)-substrate epimerization" evidence="1">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor; specific for (S)-substrate epimerization" evidence="1">
        <location>
            <position position="238"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="190"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="215"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR634603-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR634603-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU366006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL77083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="327" mass="35826" checksum="E923187E5A5CFE5E" modified="2016-01-20" version="1">MRNPFRLSYGVSDTRDVYWLRLEGDEGWGEAAIPPYYGVDTPAMIAVWQRAAHNLQPFPDEPQAVAAWVGGDGPAPARCALELALYDRIARRQGVPLWQLLHLPQPQKIATSFTIAIDTPEAMAEMASGIASFPIIKVKLGSEDDEARLAAIRSARPDVKLRVDANAGWTLEQARDLVDRLCRYDLEMIEQPLPKEQIEAMGALQKKCPVPVTADESVQTLQDVERLAAAGVQAINVKLMKVGGITPALHIFRRAQELGLRVMLGQMIETSIGATAMAHFTGLAEWVDLDSPMLVSNDPFEGILYDAHAVIQMPARVGIGVRGLESD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X396</accession>
    <name>A0A0P6X396_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_09475</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062747.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77339">
        <property type="protein sequence ID" value="KPL77339"/>
        <property type="gene ID" value="ADN00_09475"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL77339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="251" mass="27666" checksum="410F66275C2B5A53" modified="2016-01-20" version="1">MNYFGIDIGCSSIKFGEVKLGAKVETIGFDMMLPSQASKTEKYTEALMYLVQSAEKYKGVGVGFPSVVWQDGIMDLEIQFNQIWQKVDQFLQNKNVPHFAINDADSAGFAELYNPAAPELRKGVTIVLTLGSGIGSGIFVDGKLLPNSELGMIQVKGMMAEQYAAASVKHRENLSMQEWASRLQEVITQIEIILSPDHILLGGGISADFEMYRSFLQTKRAVLAPAFYRNQAGVIGAAMYAAYCSKDYNFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X443</accession>
    <name>A0A0P6X443_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_07970</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062459.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77814">
        <property type="protein sequence ID" value="KPL77814"/>
        <property type="gene ID" value="ADN00_07970"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL77814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="218" mass="24970" checksum="0B6F6F454398D4B9" modified="2016-01-20" version="1">MNLAHFEAQLTAEQLNLWNSLDTPYRIQQYLDQIPYRREERDRSPLNVLRDNQSHCLDGGLFAAAALHRIGFPALILDLVPEPGTDDDHMLAIFQQNGLFGAVAKSNFSGLRFREPVFRGLRELVMSYFEVFFNEHGQKTLRGYTRPMRISSPYPMDWLTDETAVARLARAFYLRKMVPVLPDLPIQLNLLDERSMQSGMLGTNRDELYPGSQAGAEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X494</accession>
    <name>A0A0P6X494_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_08475</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062553.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08475"/>
    <dbReference type="EnsemblBacteria" id="KPL77896">
        <property type="protein sequence ID" value="KPL77896"/>
        <property type="gene ID" value="ADN00_08475"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003797">
        <property type="entry name" value="DegV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043168">
        <property type="entry name" value="DegV_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02645">
        <property type="entry name" value="DegV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00762">
        <property type="entry name" value="DegV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51482">
        <property type="entry name" value="DEGV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="294" mass="32571" checksum="C9AAED03B45A750B" modified="2016-01-20" version="1">MNDLIIVTDGAADMPSEWIRDYRIHILPMPVLLGGKTIYLPSPEYPSEKFYRLIHELRQTPHSSLPSMDHLTRFYESIAIKGDEILSIHVAQRMSGTFSVVQSVANELKDRFQIYPFDSGAGSAALGMMCRQARQLAERGLSMDTIINQLEKAKKSLAIVLTLENLDFARLSGRINAIQSMLSSVLRINPIIELREGLLQVAGRVRTRKKAIDQLIEMVTEKAKAQKMRFAVVHAADPFAAATIKERLEAAIKAADISICELALPVAANLGPGTVGIVAYPDDESTNEDIERDN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X4A7</accession>
    <name>A0A0P6X4A7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">DNA topoisomerase 1</fullName>
            <ecNumber evidence="10">5.6.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">DNA topoisomerase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">topA</name>
        <name evidence="12" type="ORF">ADN00_08275</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Releases the supercoiling and torsional tension of DNA, which is introduced during the DNA replication and transcription, by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at a target site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(5'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 3'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand, thus removing DNA supercoils. Finally, in the religation step, the DNA 3'-OH attacks the covalent intermediate to expel the active-site tyrosine and restore the DNA phosphodiester backbone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP-independent breakage of single-stranded DNA, followed by passage and rejoining.</text>
            <dbReference type="EC" id="5.6.2.1"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the type IA topoisomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.1" evidence="10"/>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08275"/>
    <dbReference type="EnsemblBacteria" id="KPL77915">
        <property type="protein sequence ID" value="KPL77915"/>
        <property type="gene ID" value="ADN00_08275"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.657"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003917">
        <property type="term" value="F:DNA topoisomerase type I (single strand cut, ATP-independent) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00186">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03363">
        <property type="entry name" value="TOPRIM_TopoIA_TopoI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00952">
        <property type="entry name" value="Topoisom_1_prok"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000380">
        <property type="entry name" value="Topo_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003601">
        <property type="entry name" value="Topo_IA_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023406">
        <property type="entry name" value="Topo_IA_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013497">
        <property type="entry name" value="Topo_IA_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013824">
        <property type="entry name" value="Topo_IA_cen_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013825">
        <property type="entry name" value="Topo_IA_cen_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013826">
        <property type="entry name" value="Topo_IA_cen_sub3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023405">
        <property type="entry name" value="Topo_IA_core_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003602">
        <property type="entry name" value="Topo_IA_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013498">
        <property type="entry name" value="Topo_IA_Znf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005733">
        <property type="entry name" value="TopoI_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028612">
        <property type="entry name" value="Topoisom_1_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006171">
        <property type="entry name" value="TOPRIM_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034149">
        <property type="entry name" value="TOPRIM_TopoI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42785">
        <property type="entry name" value="PTHR42785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01131">
        <property type="entry name" value="Topoisom_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01751">
        <property type="entry name" value="Toprim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01396">
        <property type="entry name" value="zf-C4_Topoisom"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00417">
        <property type="entry name" value="PRTPISMRASEI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00437">
        <property type="entry name" value="TOP1Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00436">
        <property type="entry name" value="TOP1Bc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00493">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56712">
        <property type="entry name" value="SSF56712"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01051">
        <property type="entry name" value="topA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00396">
        <property type="entry name" value="TOPOISOMERASE_I_PROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50880">
        <property type="entry name" value="TOPRIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9 10 12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 10" id="KW-0799">Topoisomerase</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <keyword evidence="4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Toprim" evidence="11">
        <location>
            <begin position="1"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with DNA" evidence="10">
        <location>
            <begin position="159"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="active site" description="O-(5'-phospho-DNA)-tyrosine intermediate" evidence="10">
        <location>
            <position position="296"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="29"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="135"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="136"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="144"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="151"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="298"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with DNA" evidence="10">
        <location>
            <position position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KPL77915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="704" mass="80144" checksum="78F345AA98DF8B04" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X6R3</accession>
    <name>A0A0P6X6R3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_05770</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78747.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062018.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78747">
        <property type="protein sequence ID" value="KPL78747"/>
        <property type="gene ID" value="ADN00_05770"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01547">
        <property type="entry name" value="SBP_bac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132874" evidence="2">
        <location>
            <begin position="28"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78747.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="452" mass="48713" checksum="C07F52143E853A17" modified="2016-01-20" version="1">MKRSIYFVSTIVIVLAMLLAGCQQPPAAEPAAEAAAPTTAAEAAPAEATAPAEPAAPAETPVTIRALIRPDEGENVATYAAKFEEMTGNKVVVDFASWAEIHDKTITTLATGGGGYDIIFIPSANVVEFSSGGWFEPINDLITDANRGEWLESVVDMYTIDGDLIAMPWYAGGAHMAYNAAVLEAAGVDPASIVTWDDFMAACRKIKETGAAEFCFSPSAKYPGNFYYNWGTMVLSNGSEFFDEEGAPIFADNDAAVKSLQMIKTGIDEGLFDPAGIALDDYETLIAFGTGKIAFMLNSTWSVTQAAYNADLSTVMDDANLMLIPGNGDVRSAGYLYAGGLGLLKTSENKEVAKEFLVFLTSEEAQKHHAINGANLPTRLSLYEDADIAAAWRGFDVLAQQLTYGEFPPQFGWFEEWRRSAATAVQDVMANRKSPEDAISWLVAETNRIREQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X6U7</accession>
    <name>A0A0P6X6U7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_06000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78783">
        <property type="protein sequence ID" value="KPL78783"/>
        <property type="gene ID" value="ADN00_06000"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="387" mass="43145" checksum="0ECB0903FDDAB987" modified="2016-01-20" version="1">MEGFMGKPNFLFKTMLGVLLFTSLGCGFFSLSNSQMVNEQTDPVLPQELPTDIQPTEAQPPESQSEIEISYVYTDGLVTSLYHLYGTVLDNFVDVTLTNHGNANGTVIVETYIEGYTTKALDTVVVGAGESIEIHQNPRLMAEAVDKLNSEKPGTFHIKITQIDSDKELTLIEDSQQVLLYSRRDFVWIDGFETAEEYELWAAWVTPTDPKVEALIRAAADYTSSGTMWSGYGGHENDDNGGVWERLEAIWKAEEDYRLTYISTMVAYGPNTVQRMRLPAEVIEQASGNCVELAILFASAAEALGLETAIIRIPGHAYVAVRMDQVNANYYFIETTLIGRASFNDAINLGLEEWNDTIPHLEAQEEGYAWVTIQDARQKGILPIPWN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X6X6</accession>
    <name>A0A0P6X6X6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_12050</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063265.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12050"/>
    <dbReference type="EnsemblBacteria" id="KPL76072">
        <property type="protein sequence ID" value="KPL76072"/>
        <property type="gene ID" value="ADN00_12050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="17"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="186"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL76072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="382" mass="42926" checksum="A6945D0215C855B9" modified="2016-01-20" version="1">MRVLYFTRDYTPHDHRFLSALSEMDFEVFSLRLERRGMQREDRPLPPAVQQVVWKGGTSEVDVRDYPHILGSLQKVIDEVKPDVIHAGPIQSCAFLTAMSGYRPLVSMSWGSDLLVDADQNAWSRRVTRFALQHTSVLLGDCEAVRRKAQQYGFSPDRVVLFPWGVDLEQFSPGEDGGLRARLGWEDHFVLLSLRSWEPIYGIDVLVKAFALVARELPRLQLMLLGGGSQAGMIREILMKNGVMDQVHFGGQVTNEKLAGYYRACDLYLSASHSDGSSVSLMEALACGKPVLVSDIPGNLEWVESGKQGWLFKDGDVESLAQGIREAVRQQESLAEIGKASRALAEARADWRRNQLRLGEAYQMALDLYEKNMERSSGTTRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7I2</accession>
    <name>A0A0P6X7I2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Threonine synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_03630</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the threonine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061604.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03630"/>
    <dbReference type="EnsemblBacteria" id="KPL78993">
        <property type="protein sequence ID" value="KPL78993"/>
        <property type="gene ID" value="ADN00_03630"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.78"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004450">
        <property type="entry name" value="Thr_synthase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00260">
        <property type="entry name" value="thrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PALP" evidence="5">
        <location>
            <begin position="85"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="4">
        <location>
            <position position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR604450-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL78993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="421" mass="44547" checksum="DBC7839B86572E80" modified="2016-01-20" version="1">MNKQTIFRFAGYKCSLCGHEFGPGEVTYVCPHDGGNLDVVLDYQAIRASVQISDITSQTEPSLWRYLPLLPVSDPGFSGTPLHMAGWTPLYQPERLAKELGLQQLWVKDEGRNPTASFKDRASSVVVARAREIGAEVVVTASTGNAGAALAGMSAAVGQKAVIFAPKTAPPAKVAQLLIYGSRVILVDGNYDSAFDLTIQAANEFGWYCRNTGYNPFTAEGKKTAALEVWEQVLLKMKGAKKPLALFVSVGDGNIISGIHKGFKDLQALGWLEQMPRIFGIQSENSAAVANAYFAGTEVITPVSATTIADSISVDLPRDGVRAVRAATQTNGAYITVSDEEILSAIPELGKVGIFAEPAGSTAYAGLVKAIRTGQIGPDDPVLVLNTGNGLKDVKSAMKAAGEAPVIEPSMKALNAFLAKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7N4</accession>
    <name>A0A0P6X7N4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_03885</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061652.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03885"/>
    <dbReference type="EnsemblBacteria" id="KPL79039">
        <property type="protein sequence ID" value="KPL79039"/>
        <property type="gene ID" value="ADN00_03885"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035277">
        <property type="entry name" value="MalF_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="30"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="176"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="221"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="283"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="90"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL79039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="318" mass="36154" checksum="BA3E63DCE0904643" modified="2016-01-20" version="1">MSITTANEMSTSTVKGKQKKKGLASQEARLGYLFLTPWILGFLVFTMIPMVSTLVISFTNYSLNNVNNLQFVGLRNYAKLFSDPIVPHAMSVTLRFFAMALPIAIFLPLGLAALMNSKHLWGKRIFRTLFYMPYMIPLVSAVLAWGGFLNEQTGWMNRFLALFGIPGPEWIRSTTWIYPALLLFGLWGNGQAMITMLAGMQNVPTDMYEAARVDGANNFTIFWKITVPMVSPIIFYNLILAVVGLFQYFLEPYVLTRGTGDPGNATMFYNLYMFKNFFQYQDMAYGATLAWVLFLAILTVTLIIFGTRRFWVYEAERS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X858</accession>
    <name>A0A0P6X858_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Isoleucine--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Isoleucyl-tRNA synthetase</fullName>
            <shortName evidence="8">IleRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ileS</name>
        <name evidence="11" type="ORF">ADN00_07135</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-isoleucine + tRNA(Ile) = AMP + diphosphate + L-isoleucyl-tRNA(Ile)</text>
            <dbReference type="Rhea" id="RHEA:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:9666"/>
            <dbReference type="Rhea" id="RHEA-COMP:9695"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58045"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78528"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="8">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">IleRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated valine is translocated from the active site to the editing site, which sterically excludes the correctly activated isoleucine. The single editing site contains two valyl binding pockets, one specific for each substrate (Val-AMP or Val-tRNA(Ile)).</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.5" evidence="8"/>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78240.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062293.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07135"/>
    <dbReference type="EnsemblBacteria" id="KPL78240">
        <property type="protein sequence ID" value="KPL78240"/>
        <property type="gene ID" value="ADN00_07135"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3245"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004822">
        <property type="term" value="F:isoleucine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006428">
        <property type="term" value="P:isoleucyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07961">
        <property type="entry name" value="Anticodon_Ia_Ile_ABEc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02003">
        <property type="entry name" value="Ile_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033709">
        <property type="entry name" value="Anticodon_Ile_ABEc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002301">
        <property type="entry name" value="Ile-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023586">
        <property type="entry name" value="Ile-tRNA-ligase_type2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42780">
        <property type="entry name" value="PTHR42780"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00984">
        <property type="entry name" value="TRNASYNTHILE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="SSF50677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00392">
        <property type="entry name" value="ileS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 8" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="tRNA-synt_1" evidence="9">
        <location>
            <begin position="18"/>
            <end position="635"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_1" evidence="10">
        <location>
            <begin position="682"/>
            <end position="831"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="8">
        <location>
            <begin position="48"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="8">
        <location>
            <begin position="597"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="600"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00025217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL78240.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="1049" mass="119417" checksum="003455E8B356E839" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X865</accession>
    <name>A0A0P6X865_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Exodeoxyribonuclease 7 small subunit</fullName>
            <ecNumber evidence="3">3.1.11.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Exodeoxyribonuclease VII small subunit</fullName>
            <shortName evidence="3">Exonuclease VII small subunit</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">xseB</name>
        <name evidence="4" type="ORF">ADN00_16800</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.</text>
            <dbReference type="EC" id="3.1.11.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heterooligomer composed of large and small subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the XseB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.11.6" evidence="3"/>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064209.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16800"/>
    <dbReference type="EnsemblBacteria" id="KPL71366">
        <property type="protein sequence ID" value="KPL71366"/>
        <property type="gene ID" value="ADN00_16800"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009318">
        <property type="term" value="C:exodeoxyribonuclease VII complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008855">
        <property type="term" value="F:exodeoxyribonuclease VII activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1040">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00337">
        <property type="entry name" value="Exonuc_7_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003761">
        <property type="entry name" value="Exonuc_VII_S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037004">
        <property type="entry name" value="Exonuc_VII_ssu_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34137">
        <property type="entry name" value="PTHR34137"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02609">
        <property type="entry name" value="Exonuc_VII_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006488">
        <property type="entry name" value="Exonuc_VII_S"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116842">
        <property type="entry name" value="SSF116842"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01280">
        <property type="entry name" value="xseB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL71366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="73" mass="8238" checksum="08BF518A4DDD6907" modified="2016-01-20" version="1">MAKKTSDVEKLSYEQAFAELEQIIATLENEQPTLDEATALFERGQALMQHCASLLDQAELKIRKLSNAELDQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X885</accession>
    <name>A0A0P6X885_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phospho-N-acetylmuramoyl-pentapeptide-transferase</fullName>
            <ecNumber evidence="7">2.7.8.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">UDP-MurNAc-pentapeptide phosphotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">mraY</name>
        <name evidence="8" type="ORF">ADN00_07370</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the initial step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan: transfers peptidoglycan precursor phospho-MurNAc-pentapeptide from UDP-MurNAc-pentapeptide onto the lipid carrier undecaprenyl phosphate, yielding undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide, known as lipid I.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>di-trans,octa-cis-undecaprenyl phosphate + UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-gamma-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine = di-trans-octa-cis-undecaprenyl diphospho-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimeloyl-D-alanyl-D-alanine + UMP</text>
            <dbReference type="Rhea" id="RHEA:28386"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:60392"/>
            <dbReference type="ChEBI" id="CHEBI:61386"/>
            <dbReference type="ChEBI" id="CHEBI:61387"/>
            <dbReference type="EC" id="2.7.8.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="7">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the glycosyltransferase 4 family. MraY subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.13" evidence="7"/>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062338.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07370"/>
    <dbReference type="EnsemblBacteria" id="KPL78277">
        <property type="protein sequence ID" value="KPL78277"/>
        <property type="gene ID" value="ADN00_07370"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3296"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008963">
        <property type="term" value="F:phospho-N-acetylmuramoyl-pentapeptide-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051992">
        <property type="term" value="F:UDP-N-acetylmuramoyl-L-alanyl-D-glutamyl-meso-2,6-diaminopimelyl-D-alanyl-D-alanine:undecaprenyl-phosphate transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06852">
        <property type="entry name" value="GT_MraY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00038">
        <property type="entry name" value="MraY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000715">
        <property type="entry name" value="Glycosyl_transferase_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003524">
        <property type="entry name" value="PNAcMuramoyl-5peptid_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018480">
        <property type="entry name" value="PNAcMuramoyl-5peptid_Trfase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22926">
        <property type="entry name" value="PTHR22926"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00953">
        <property type="entry name" value="Glycos_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00445">
        <property type="entry name" value="mraY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01347">
        <property type="entry name" value="MRAY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01348">
        <property type="entry name" value="MRAY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7" id="KW-0132">Cell division</keyword>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0133">Cell shape</keyword>
    <keyword evidence="7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="125"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="155"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="186"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="210"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="235"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="260"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="315"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL78277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="334" mass="36570" checksum="0D0FE27239B09A61" modified="2016-01-20" version="1">MTEASLSLALSTLSFMMAVIWGGPLIRILRHLRIGKLIRVEGPNSHITKMGTPTMGGLMIIVPVVLLTGLLNAASLIGLRTQVMGQSVLLPMLVMVFYGLLGMIDDWEGVRGPRRGLGMRARTKFAFQAIFAFVIAIILRYVLHVPEMYWLGVNRPFELGIIFLPIAMFIIIGGSNAINFTDGLDGLAGLISATAFAAYGAIALLQGQVYLTRFCFTLVGALFGFLWFNVHPAELFMGDTGSLSLGATLGVIALMTGQWLLLPIIIIIPVSEALSVIIQIVYFKLTGGKRFFKMAPLHHHFELTGWSETQVVQRFWLVSLLSAMLGIALMFVKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X8D0</accession>
    <name>A0A0P6X8D0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">OmpA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_17225</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the MotB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064290.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17225"/>
    <dbReference type="EnsemblBacteria" id="KPL71430">
        <property type="protein sequence ID" value="KPL71430"/>
        <property type="gene ID" value="ADN00_17225"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.507"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07185">
        <property type="entry name" value="OmpA_C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025713">
        <property type="entry name" value="MotB_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006665">
        <property type="entry name" value="OmpA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036737">
        <property type="entry name" value="OmpA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13677">
        <property type="entry name" value="MotB_plug"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00691">
        <property type="entry name" value="OmpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103088">
        <property type="entry name" value="SSF103088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51123">
        <property type="entry name" value="OMPA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="OmpA-like" evidence="6">
        <location>
            <begin position="126"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL71430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="266" mass="28900" checksum="A5AA9778967A977D" modified="2016-01-20" version="1">MSDSQGGLHEEEHAGHDERWLVSYADFITLLMVLFVVLYSMGQVDVEKYKQLAESMRAAFSLGGPAQVIDAGINSSGGSMEDGKPNPIVIPGIPMRPPQSEEVAGELTYMLASQNLGGEVSVQTNVEGVLISLSEKLIFDPGTAQLQADAYPVLDTIVEMVRPIENQVRVVGHTDNTPPTDPRFHNNWELSTGRASVIAEYMISKGIAPTRITISGRGEYEPIFPNDSEQHRALNSRADIVIIYRVASNHVGLDTNHLDTSSAAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X8T8</accession>
    <name>A0A0P6X8T8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Sensor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_03225</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000014">
        <property type="protein sequence ID" value="KPL79350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061518.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000014.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79350">
        <property type="protein sequence ID" value="KPL79350"/>
        <property type="gene ID" value="ADN00_03225"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025828">
        <property type="entry name" value="Put_sensor_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13796">
        <property type="entry name" value="Sensor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="170"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="Sensor" evidence="2">
        <location>
            <begin position="27"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="231" mass="25183" checksum="EBF8E5F91D303AC5" modified="2016-01-20" version="1">MKNQSIFARIFGVYIQPRTYGGILFQLLALPLGIVYFTLLVTGFALGIPLIIVWVGIPILLLVMGIAWGFTAFERISAIGLLGVKVPPMSRPAIPGASIWKRFINYLGNPVTWKGLIYLLIKLPIGIGTFTAVVTLLSVPLAMIFSPMVLFIPNVHIDLTFWRIDTLPEVIAMMTMGFVLLTLSLHILNFFSYLLGELARVMLGNAGAAAPAAPAISQPASMPIETQEQTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X924</accession>
    <name>A0A0P6X924_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_12080</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063271.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12080"/>
    <dbReference type="EnsemblBacteria" id="KPL76076">
        <property type="protein sequence ID" value="KPL76076"/>
        <property type="gene ID" value="ADN00_12080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015774">
        <property type="term" value="P:polysaccharide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007833">
        <property type="entry name" value="Capsule_polysaccharide_synth"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05159">
        <property type="entry name" value="Capsule_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="539" mass="62206" checksum="F26D2D74518DC186" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XA45</accession>
    <name>A0A0P6XA45_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AlaDh_PNT_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_03325</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061543.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03325"/>
    <dbReference type="EnsemblBacteria" id="KPL78944">
        <property type="protein sequence ID" value="KPL78944"/>
        <property type="gene ID" value="ADN00_03325"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007886">
        <property type="entry name" value="AlaDH/PNT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05222">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01003">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AlaDh_PNT_N" evidence="1">
        <location>
            <begin position="8"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="375" mass="41538" checksum="1A7910E4BDEF1F1B" modified="2016-01-20" version="1">MYHRISIGLARMHAEKNERRDFLPEFVGQLENNGYDVLLEEGYGSGLGLSKDAYLAAAPGAVFASKKHIFQQDYVLVLRYPGDEIVQQMQPGSCLISMLHYPTRPHRVKFLRDLGVNGISLDSLADDNGRRLVENLRAVAWNGVGVAFDLMEQIYPAPGLGSPRREAVRVVLLGAGAVGHHAVQAAIHYGDPARHRRLASEGAPGVLVQVVDYDLTGRVEVMRPLLKTADLLIDATSRINPSKPVIPNEWIGEMPGHAILLDLSVDPYDFQIEPPIVKGIEGVPQGNLDQYIFAPDSPAFERVPAGVDTRNRRHSVSCYSWPGIKPGECMEVYGNQLRPLLRTLIESGGLERIPPDGNFFQRALYRASLAHWDER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAA6</accession>
    <name>A0A0P6XAA6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Putative nickel insertion protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_03760</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the LarC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061627.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03760"/>
    <dbReference type="EnsemblBacteria" id="KPL79017">
        <property type="protein sequence ID" value="KPL79017"/>
        <property type="gene ID" value="ADN00_03760"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.105"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01074">
        <property type="entry name" value="LarC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002822">
        <property type="entry name" value="Ni_insertion"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36566">
        <property type="entry name" value="PTHR36566"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01969">
        <property type="entry name" value="DUF111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00299">
        <property type="entry name" value="TIGR00299"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="1 2" id="KW-0533">Nickel</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="415" mass="45455" checksum="77CDD8E0F8813DE4" modified="2016-01-20" version="1">MTRIAYLDCFSGIAGDMLLAAMVDAGLPQDYLTDQIGTLAIHEPYKLRFEETRKGSLRALRFFVEEHKHEHIHGHEHAHEDDHVHGHADTAHAPGQHRHLSEIEMLIDNSGLTARAKSIARLVFLKLAEAEAKVHGSRVEEVHFHEVGALDSIIDVVGAAVGLDYFGIERLYASDLPFTSGHVHSQHGIIPVPAPAVLALLEAVNAPLQPVAARMELVTPTGAAIVAALAAFERPAMRLEKVGVGAGKKDLEWPNILRLMIGSPAEEKRPLILMETNIDDMNPELYAPVMDALFQAGALDVFLSPIYMKKNRPAVKLSVIARKENEAALAGMILRQTSTFGLRVLAIERHEAEREIRQVSTVFGEVGVKVKFMDGKACQVSPEYEDCARLSKERGVAAQDVYLAALRAADSLLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAL3</accession>
    <name>A0A0P6XAL3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Enolase</fullName>
            <ecNumber evidence="8">4.2.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">2-phospho-D-glycerate hydro-lyase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">2-phosphoglycerate dehydratase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8 13" type="primary">eno</name>
        <name evidence="13" type="ORF">ADN00_04705</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(2R)-2-phosphoglycerate = H2O + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:10164"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="EC" id="4.2.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="8">The covalent binding to the substrate causes inactivation of the enzyme, and possibly serves as a signal for the export of the protein.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 4/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Secreted</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="8">Cell surface</location>
        </subcellularLocation>
        <text evidence="8">Fractions of enolase are present in both the cytoplasm and on the cell surface. The export of enolase possibly depends on the covalent binding to the substrate; once secreted, it remains attached to the cell surface.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the enolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.11" evidence="8"/>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061801.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04705"/>
    <dbReference type="EnsemblBacteria" id="KPL79155">
        <property type="protein sequence ID" value="KPL79155"/>
        <property type="gene ID" value="ADN00_04705"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.303"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00187"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009986">
        <property type="term" value="C:cell surface"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000015">
        <property type="term" value="C:phosphopyruvate hydratase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004634">
        <property type="term" value="F:phosphopyruvate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03313">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00318">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000941">
        <property type="entry name" value="Enolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036849">
        <property type="entry name" value="Enolase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029017">
        <property type="entry name" value="Enolase-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020810">
        <property type="entry name" value="Enolase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020809">
        <property type="entry name" value="Enolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020811">
        <property type="entry name" value="Enolase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11902">
        <property type="entry name" value="PTHR11902"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00113">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03952">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001400">
        <property type="entry name" value="Enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00148">
        <property type="entry name" value="ENOLASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00002">
        <property type="entry name" value="enolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01192">
        <property type="entry name" value="Enolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01193">
        <property type="entry name" value="Enolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51604">
        <property type="entry name" value="SSF51604"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54826">
        <property type="entry name" value="SSF54826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01060">
        <property type="entry name" value="eno"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00164">
        <property type="entry name" value="ENOLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="7 8 13" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="Enolase_N" evidence="12">
        <location>
            <begin position="5"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="Enolase_C" evidence="11">
        <location>
            <begin position="140"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="8 10">
        <location>
            <begin position="368"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8 9">
        <location>
            <position position="207"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8 9">
        <location>
            <position position="341"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="289"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="316"/>
        </location>
    </feature>
    <feature type="binding site" description="covalent; in inhibited form" evidence="8">
        <location>
            <position position="341"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8 10">
        <location>
            <position position="392"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001400-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KPL79155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="432" mass="46423" checksum="77C3391BF7665566" modified="2016-01-20" version="1">MDTTIDMITAQQILDSRGNPTIEVEVVLTDGSWGRAAVPSGASTGIHEALELRDGDKSVYLGKGVLQAVENVNDTIAEALFGFDATDQRAIDLTLLELDGTPNKSKLGANAILGTSLAVAKAAASAVALPLYRYIGGVHAHVLPVPMMNILNGGAHTGWQSTDAQEFMVMPLGAPNFSECVRWGAEIYHALKGVLKAHGYTTLVGDEGGYAPALKSNAEAVELILEAIEKAGYKAGEQVAIALDPAASEFYDADEKLYNLRKEGKKLSSEQMVAFWKSWVDQYPIVSVEDGFAQDDWEGWQMFTAEMGGRIQIVGDDLVVTNPNRIRRAIAEKSCNSLLVKLNQIGSLTETIEAVELAHRAGWTTVTSHRSGETEDSTIADLAVALNTGQIKTGAPARSDRVAKYNQLLRIEAELGETAVFAGWNALKQAHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAQ7</accession>
    <name>A0A0P6XAQ7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HlyD_D23 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_09185</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77297">
        <property type="protein sequence ID" value="KPL77297"/>
        <property type="gene ID" value="ADN00_09185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HlyD_D23" evidence="2">
        <location>
            <begin position="155"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="28"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="154"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="325" mass="34631" checksum="273E00982B9BA0FE" modified="2016-01-20" version="1">MLVQSGETVKTGQVLVRLAGSEQQAAAVEAARTELMAAEQALKDIQLNAEQSRAAALLRLANAGKALDDAKKVRGYREYRNGSDSMVASAQADLILATDTLDKAQEAYNYVSKYDDKNLLKAGALSALSNAQKAYDRAVANLNYVSSMPSQVDVDLAEAQLQSAQAEYDIAKREYEELAEGIDPDVLAMAEQRVKNGKAQLAASLSALADVELVAPFDGIAANVKVDSGSWVSPGQTMLIVADLEHLQVETSDLSERDVPSVRVGQPVRVFIKALGQTLEGKVSEISPIAETLGGDVVYTTVISLEEIPASLLIGMSAEVNYLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAS6</accession>
    <name>A0A0P6XAS6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_09500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77343.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062752.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09500"/>
    <dbReference type="EnsemblBacteria" id="KPL77343">
        <property type="protein sequence ID" value="KPL77343"/>
        <property type="gene ID" value="ADN00_09500"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4139"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002328">
        <property type="entry name" value="ADH_Zn_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00059">
        <property type="entry name" value="ADH_ZINC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="ADH_N" evidence="4">
        <location>
            <begin position="28"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="ADH_zinc_N" evidence="3">
        <location>
            <begin position="175"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU361277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL77343.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="355" mass="38839" checksum="785FEAE4A014D013" modified="2016-01-20" version="1">MKTMKAMVLEEPRKFVYKDVPVPAISDDEVLIKVKYCGICGSDWGSYNGFYEEEVACLPLITGHEFWGVIEEAGKNVTSVKPGDRVAVDICLPCGTCYYCRRGESLLCSTFKQIGIHVDGAFAEYVKAPAVNCYLLPDEIDDYAAAFIEPLTACINASRKMNCELGASVAVIGAGLGTIHALLAKLRGAAPVFVIDSQQKRLETAKMMSADVVIDITKTPDPVAEIKRLTGGVGVDYVIEAVGKSQTYEQAFNMLRRGGKLEAFGICSDDDFVKLPPAKFVLEEKKIGGSCAGIGHDWEVAIALLQYKRVDPHPLISMVVPLYELEEALNELHQNKNLVKVLVSPEITERIILTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XB00</accession>
    <name>A0A0P6XB00_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_03100</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000014">
        <property type="protein sequence ID" value="KPL79328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061497.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000014.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79328">
        <property type="protein sequence ID" value="KPL79328"/>
        <property type="gene ID" value="ADN00_03100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="101" mass="11656" checksum="44E7D6541D140396" modified="2016-01-20" version="1">MGFLSDLLFPPIPSGAREEVERLVKELVEIGPRDDFLSERPGRPFNNQCRHIRGVEIGKRLNDLGGYNLMDYVLRRVRRKLGKELAAHLEYCWMGIGSWLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBN6</accession>
    <name>A0A0P6XBN6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PpiC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_15080</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063865.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15080"/>
    <dbReference type="EnsemblBacteria" id="KPL72156">
        <property type="protein sequence ID" value="KPL72156"/>
        <property type="gene ID" value="ADN00_15080"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.718"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000297">
        <property type="entry name" value="PPIase_PpiC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023058">
        <property type="entry name" value="PPIase_PpiC_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027304">
        <property type="entry name" value="Trigger_fact/SurA_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109998">
        <property type="entry name" value="SSF109998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01096">
        <property type="entry name" value="PPIC_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50198">
        <property type="entry name" value="PPIC_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0697">Rotamase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="27"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="domain" description="PpiC" evidence="4">
        <location>
            <begin position="285"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="197"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="213"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL72156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="433" mass="48628" checksum="0A9028405E6F93C0" modified="2016-01-20" version="1">MAEKKSPRFTNKKHVARLERENQQRKILITISVIVVAAVLLTIGIGLLYDKVLKYNQPVAEVNGEKIKLGEYQDTVRYNRYQAVQQYLQYYAFYEAYPDFGASLQPQLQQIQTQLEEDYAGILGSSVLDRMVDDVIVRQQAELKGITVSQEEIDARMEQYFGYNQENIATPTPFPTIAPTSTLSAEQLAIITVTPTATATEPPAEPTATPEPTAVPEEQSSEPTATPFPTATPFTQEGYNQLKDEFFTQLSDAGISKAFFTEFIRSILLREKLVDEITRDYAVVQEQVWARHILVADEAAAQVVRERLENGEDFGEVAKEVSTDSSNSANGGDLGYFPRGMMDPSFEEAAFSLQVGEISQPVESQFGWHIIQVLGKEDRALDQSTYESARQGVFQKWFDEVKSGLEIETFDSYLDQTPVEPNIPLDKRMPSTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XCG4</accession>
    <name>A0A0P6XCG4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_01815</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000006">
        <property type="protein sequence ID" value="KPL80124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061254.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000006.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80124">
        <property type="protein sequence ID" value="KPL80124"/>
        <property type="gene ID" value="ADN00_01815"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025302">
        <property type="entry name" value="DUF4162"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13732">
        <property type="entry name" value="DUF4162"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="6"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL80124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="310" mass="34169" checksum="E935F8626757DA0E" modified="2016-01-20" version="1">MSTNAILTRSLSRSFGAVQALSQVSFEVPQSIVFGYLGPNGSGKTTTIRLLLGLLEPDAGEAEVLGYNTRTQAQEIRENCGALLEHTGLYERMSAMENLDFYARVWHLPAAERAQRIQSLLGDLGLWERRDEKVGGWSRGMKQKLAVARALLHRPRLLFLDEPTAGLDPVAAAALREDLAALVEQQGVTVFLTTHNLSEAERLCARVAVIDRGRLLAVGSPDELRSRQGGQRLEIHGRGINDEVIDSLRQRPEVARAARENQHLLVDLNENSESAAIVSYLVQAGVEIEEVRKGKASLEEAFLTLLEDEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDP6</accession>
    <name>A0A0P6XDP6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_00910</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061067.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL81115">
        <property type="protein sequence ID" value="KPL81115"/>
        <property type="gene ID" value="ADN00_00910"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL81115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="107" mass="11062" checksum="5B1474BFA2162D96" modified="2016-01-20" version="1">MIPITVHDLILTMAVSMFVIGLVSIGAGVFLLVTKIIGEDVKTIAKQTTQIAQKGLADDIAGLVGNASSLIEGLNQLVKTTSGIGTFLVVVGIVIVVASFLMALQIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDQ4</accession>
    <name>A0A0P6XDQ4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_00220</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060944.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00220"/>
    <dbReference type="EnsemblBacteria" id="KPL81011">
        <property type="protein sequence ID" value="KPL81011"/>
        <property type="gene ID" value="ADN00_00220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016884">
        <property type="term" value="F:carbon-nitrogen ligase activity, with glutamine as amido-N-donor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1510.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003789">
        <property type="entry name" value="Asn/Gln_tRNA_amidoTrase-B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023168">
        <property type="entry name" value="GatB_Yqey_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019004">
        <property type="entry name" value="YqeY/Aim41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042184">
        <property type="entry name" value="YqeY/Aim41_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28055">
        <property type="entry name" value="PTHR28055"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09424">
        <property type="entry name" value="YqeY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89095">
        <property type="entry name" value="SSF89095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL81011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="148" mass="16626" checksum="F43F6795F9CA66EB" modified="2016-01-20" version="1">MNKKEELEQALKLAMKAGDDTRKRTIRMALSNIKLQEIEKRASLDDATIISLLQKEIKMRNESIEGAKKLNRTDLIDANLDEIRVLESFLPAQLSEDDVRKIAEAVIKEMNATTPAEMGKVMKELLPRLQGQAPNSLASQVVKQLLSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDY9</accession>
    <name>A0A0P6XDY9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">PMT_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ADN00_06830</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000018">
        <property type="protein sequence ID" value="KPL78431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062233.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000018.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06830"/>
    <dbReference type="EnsemblBacteria" id="KPL78431">
        <property type="protein sequence ID" value="KPL78431"/>
        <property type="gene ID" value="ADN00_06830"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038731">
        <property type="entry name" value="RgtA/B/C-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13231">
        <property type="entry name" value="PMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="133"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="199"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="235"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="264"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="296"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="334"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="399"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="428"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="domain" description="PMT_2" evidence="9">
        <location>
            <begin position="58"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL78431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="619" mass="68979" checksum="E64087E22EDDFAEC" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XG11</accession>
    <name>A0A0P6XG11_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_14480</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000034">
        <property type="protein sequence ID" value="KPL73765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063740.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000034.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL73765">
        <property type="protein sequence ID" value="KPL73765"/>
        <property type="gene ID" value="ADN00_14480"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1416"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL73765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="299" mass="32234" checksum="3E9F8280C208E170" modified="2016-01-20" version="1">MIEISNLSKTYGSGAQAVKALSGVHLTIEEGMFGLLGPNGAGKTTLMRILAGIAQPSAGKVVIAGYNLADEKARTDYKAMLGYLPQELGMYPDLTARQFVDYMAILKGMHIPAQRQHRVDEVLDMVGLSEAAGRKIKSFSGGMKRRVGIAQALVNDPRVLIVDEPTAGLDPEERIRFRNLLVDLAANRVVLLSTHIVEDIGQTCQKMAVLSRGRILYTGSPRELTGMAEGRVWTVTTQSTTKPNNGLTVVSMLHLAEGVQYRLVGASAAEYEGAVTAKPGLEDGYVWLMKSAGYEAAIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XG76</accession>
    <name>A0A0P6XG76_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Aminopeptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_04875</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="8">Binds 2 divalent metal cations per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase M42 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79181.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061829.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04875"/>
    <dbReference type="EnsemblBacteria" id="KPL79181">
        <property type="protein sequence ID" value="KPL79181"/>
        <property type="gene ID" value="ADN00_04875"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008007">
        <property type="entry name" value="Peptidase_M42"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023367">
        <property type="entry name" value="Peptidase_M42_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05343">
        <property type="entry name" value="Peptidase_M42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001123">
        <property type="entry name" value="PepA_GA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 9" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="194"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="63"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="164"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="195"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="217"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="303"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR001123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001123-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001123-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL79181.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="332" mass="35833" checksum="69BDFD0B33E1249D" modified="2016-01-20" version="1">MKELLKKLVQIPAPFGYESAMRDAVRAEITNLADEIQVDALGNLIARKGQRGPDGLRVMLSAHMDEIGIIASHVDENGFVRFAPLGNVYAHNCPGARVRFLNGARGLIGSPRYTSSSQPPAIPDMFIDVGATSREDCPVKVGDPAVFENTFLDLGQRVAAKSLDNRISVAAQIEIMRRLSTSPHEIHFVFSVQEEVGQKGALVAAYHLQPELGIALDVTTTGDTPNSARMAVELGKGPAIKVKDEGMIADPRVVRLLAGAAEKLNIPTQREILLNGTTDARWMQAQRAGAPAGTLSIPCRYVHSPSEMVDLGDVEHAVNLMVHLLSAPVHLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGC9</accession>
    <name>A0A0P6XGC9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_05820</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05820"/>
    <dbReference type="EnsemblBacteria" id="KPL78755">
        <property type="protein sequence ID" value="KPL78755"/>
        <property type="gene ID" value="ADN00_05820"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="118"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="118"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL78755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="222" mass="24735" checksum="70334066C25860A8" modified="2016-01-20" version="1">MRRSLAFHLEQAGYQVHTAASAEDALIWVTQNRPDLVLLDIGLPGMDGLDALRELKTRHNVPVIFITARRRELDEVVGLELGADDYVTKPFDVDVVLARIKAVLRRVGAPVLSTEKQVSVLTIGDLVISPDSHSVLCSDRPVDLSPRLFDLLLALASQPEKVISTEDLLSQVWGAEFEGQPQVVYVHIRWLREALEEDPDHPQRILTVRGVGYKLIPKAAEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGV6</accession>
    <name>A0A0P6XGV6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_14050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063659.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000033.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74121">
        <property type="protein sequence ID" value="KPL74121"/>
        <property type="gene ID" value="ADN00_14050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008969">
        <property type="entry name" value="CarboxyPept-like_regulatory"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49464">
        <property type="entry name" value="SSF49464"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="147" mass="15656" checksum="F96D0825363661DF" modified="2016-01-20" version="1">MSLDNSPKLDQFKNGLPTQLPDVTARRRRQRLALTGLVVCLLALAGFQFLRSDPASHLAGVGKITGSLVDEQSGLPVTGEVFISGSDQIIQTDASGRFELFGVPSGPQSLVVVYRNTGRAYPIEVPRGSTLDVGSLSAPTLARSYLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGX4</accession>
    <name>A0A0P6XGX4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_03775</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061630.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03775"/>
    <dbReference type="EnsemblBacteria" id="KPL79020">
        <property type="protein sequence ID" value="KPL79020"/>
        <property type="gene ID" value="ADN00_03775"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037522">
        <property type="entry name" value="HD_GYP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51832">
        <property type="entry name" value="HD_GYP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS" evidence="1">
        <location>
            <begin position="158"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="2">
        <location>
            <begin position="209"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="1">
        <location>
            <begin position="281"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="2">
        <location>
            <begin position="338"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="1">
        <location>
            <begin position="591"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="domain" description="HD-GYP" evidence="3">
        <location>
            <begin position="1066"/>
            <end position="1257"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL79020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="1257" mass="142518" checksum="3D13112B65863B1D" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XHP0</accession>
    <name>A0A0P6XHP0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Phosphoglucosamine mutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_03165</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000014">
        <property type="protein sequence ID" value="KPL79340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061510.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000014.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03165"/>
    <dbReference type="EnsemblBacteria" id="KPL79340">
        <property type="protein sequence ID" value="KPL79340"/>
        <property type="gene ID" value="ADN00_03165"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2045"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016868">
        <property type="term" value="F:intramolecular transferase activity, phosphotransferases"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005841">
        <property type="entry name" value="Alpha-D-phosphohexomutase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00509">
        <property type="entry name" value="PGMPMM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="SSF53738"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="SSF55957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGM_PMM_I" evidence="6">
        <location>
            <begin position="4"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_II" evidence="7">
        <location>
            <begin position="175"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_III" evidence="8">
        <location>
            <begin position="280"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_IV" evidence="5">
        <location>
            <begin position="433"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL79340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="486" mass="52777" checksum="C956E5FF4BF63E61" modified="2016-01-20" version="1">MTIHFGTDGWRAVISDTFTFHNLRLVTQAVADAVASPHWMNGNAPEPAPDAKKMVVGFDTRFLSDRYAKEVARVLAANGFRVYLSQADAPTPAISYSVKYLGAIGGVMITASHNAPRYNGVKLKSARGNSASPEQCRRVEVYLNDNEQQGRGPNLMDYEKATQAGLITRFNPIPAYYDHLRELIDMDTISEARQRVVVDSMYGSGRGVIRGILQGTACEVTEIRGEMNPGFGGVHPEPIGRYLGTLAGAISTGLGNFGLATDGDADRIGAMDERGNFVDPHKIMALSLKHLVEKRGLSGSVIRTVSTTRMVDRLAAKYGLPVRETPVGFNHIADYMMKEDVLIGGEESGGISFKGHIPEGDGIIMGLLLLEIVSANRTSLYELVENLLKEAGPSFYERRDLRLSQPVSKQIMVQKLVEEAPAQIGGESIINVGTTDGVKYLLADESWLLIRPSGTEPVLRVYAEGRSEEMVKALLAYGGQIASSVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XJD8</accession>
    <name>A0A0P6XJD8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Phosphinothricin acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_16770</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064203.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16770"/>
    <dbReference type="EnsemblBacteria" id="KPL71361">
        <property type="protein sequence ID" value="KPL71361"/>
        <property type="gene ID" value="ADN00_16770"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.412"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL71361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="166" mass="17681" checksum="8DE74FA03A59D4BA" modified="2016-01-20" version="1">MHSITIQTMSAADWPSVRAIYAEGIAGGSATFETQPPEWDAWNASHLPGGRIVARIGGEVAGWAALSPVSSRCVYAGVAEVSVYVAGAHQGRGVGLALLRALIEASEPMGLWTLQAGIFAENLASIRLHQKAGFRMVGRREKIGCLNGVWRDTILMERRSPVVGLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XJU0</accession>
    <name>A0A0P6XJU0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_12125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063280.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76084">
        <property type="protein sequence ID" value="KPL76084"/>
        <property type="gene ID" value="ADN00_12125"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3901"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="10"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="313" mass="34660" checksum="D9B0D4BEEB80465D" modified="2016-01-20" version="1">MSQNHLIFGAGPLAQSVMRALLKRGKTVKMVNRSGKRPADVPAQVEFLAGDAYNPEFTRQAAQGMNVIYQCAQPAYHRWVQDFPALQSSILQAAAASKAKLIVGENLYMYGDTKGQPIHEGLPNAAHTRKGKVRAQMSETLLEAHRAGKVRVVIARGSDFYGPAVLSSTLGERAIKPLLLGKPAEVVGALDLPHTYTYISDFGEALVILGERDEALGQIWHVPNAPTLTQRELVSLFFKEAGLPPRFSVMGKFMMSLGGLFIPEARESLEMMYQFTQPFHVDASKFIRAFGDIATPHEQAIKETLDWYRQRLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKM0</accession>
    <name>A0A0P6XKM0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Beta-galactosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_16615</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the glycosyl hydrolase 35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064161.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16615"/>
    <dbReference type="EnsemblBacteria" id="KPL72093">
        <property type="protein sequence ID" value="KPL72093"/>
        <property type="gene ID" value="ADN00_16615"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3766"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031330">
        <property type="entry name" value="Gly_Hdrlase_35_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001944">
        <property type="entry name" value="Glycoside_Hdrlase_35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23421">
        <property type="entry name" value="PTHR23421"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01301">
        <property type="entry name" value="Glyco_hydro_35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00742">
        <property type="entry name" value="GLHYDRLASE35"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_35" evidence="5">
        <location>
            <begin position="19"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL72093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="706" mass="80094" checksum="F18B2F6D6105A610" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XL58</accession>
    <name>A0A0P6XL58_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutamate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_15075</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the Glu/Leu/Phe/Val dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000038">
        <property type="protein sequence ID" value="KPL72422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063864.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000038.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15075"/>
    <dbReference type="EnsemblBacteria" id="KPL72422">
        <property type="protein sequence ID" value="KPL72422"/>
        <property type="gene ID" value="ADN00_15075"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3398"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016639">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01076">
        <property type="entry name" value="NAD_bind_1_Glu_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006095">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006096">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006097">
        <property type="entry name" value="Glu/Leu/Phe/Val_DH_dimer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033922">
        <property type="entry name" value="NAD_bind_Glu_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00208">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02812">
        <property type="entry name" value="ELFV_dehydrog_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00082">
        <property type="entry name" value="GLFDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00839">
        <property type="entry name" value="ELFV_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ELFV_dehydrog" evidence="3">
        <location>
            <begin position="64"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="4">
        <location>
            <position position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL72422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="294" mass="32320" checksum="49AC6E3E0FA61EE2" modified="2016-01-20" version="1" fragment="single">EKERLVRGWVQQMWKNIGPRQDVPAPDVGTTPQMMGWMMDEYSRLAGQYTPGVITGKPVGGGGSLGRTEATGYGVIFTVREAMKHLGMDPKVCKAAVQGFGNVAQYAAIGFTEMLGGKVVCVSYWDREDRMPYTISKDDGIAPRFLMSITDQYGSIDKAKAKAAGYQLEDAGAWIGKDVDVLIPAALEGQINAESVQKISPRVRLLAEGANGPTTPEADEVLKQRGIFVVPDFLCNAGGVTTSYFESVQNDMNFYWTKQEVLEKLDTKMTEAFHAVLEMSLKEKAYMRDAAYMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XLT0</accession>
    <name>A0A0P6XLT0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_12355</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063321.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12355"/>
    <dbReference type="EnsemblBacteria" id="KPL76124">
        <property type="protein sequence ID" value="KPL76124"/>
        <property type="gene ID" value="ADN00_12355"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3951"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd05398">
        <property type="entry name" value="NT_ClassII-CCAase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001667">
        <property type="entry name" value="DDH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038763">
        <property type="entry name" value="DHH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003156">
        <property type="entry name" value="DHHA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002646">
        <property type="entry name" value="PolA_pol_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032828">
        <property type="entry name" value="PolyA_RNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01368">
        <property type="entry name" value="DHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02272">
        <property type="entry name" value="DHHA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01743">
        <property type="entry name" value="PolyA_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12627">
        <property type="entry name" value="PolyA_pol_RNAbd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64182">
        <property type="entry name" value="SSF64182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0129">CBS domain</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="319"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="5">
        <location>
            <begin position="380"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL76124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="890" mass="99433" checksum="455DC10BF2190AA8" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XLU5</accession>
    <name>A0A0P6XLU5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cytokinin riboside 5'-monophosphate phosphoribohydrolase</fullName>
            <ecNumber evidence="1">3.2.2.n1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01035</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LOG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.n1" evidence="1"/>
    <dbReference type="EMBL" id="LGCL01000003">
        <property type="protein sequence ID" value="KPL80808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061107.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01035"/>
    <dbReference type="EnsemblBacteria" id="KPL80808">
        <property type="protein sequence ID" value="KPL80808"/>
        <property type="gene ID" value="ADN00_01035"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1951"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009691">
        <property type="term" value="P:cytokinin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005269">
        <property type="entry name" value="LOG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031100">
        <property type="entry name" value="LOG_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03641">
        <property type="entry name" value="Lysine_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00730">
        <property type="entry name" value="TIGR00730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0203">Cytokinin biosynthesis</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="187" mass="20095" checksum="79AED66EE68F72A6" modified="2016-01-20" version="1">MRSVTVYCGSSTGSSPVYLEAAHDLGRALAQSGIALVYGGGGIGMMGALAAACLESGGQVTGVITRALMETESAKKDLADMRVVETMHERKRLMAELGEAFIALPGGFGTFEELFEAATWLQLEIHRKPVGLINAGGYYTHLLTFLRHSVAEGFIKAPHLDMIQVAENARDLLEKLNGYRHISVSKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XMI1</accession>
    <name>A0A0P6XMI1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Abhydrolase_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_00540</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00540"/>
    <dbReference type="EnsemblBacteria" id="KPL81055">
        <property type="protein sequence ID" value="KPL81055"/>
        <property type="gene ID" value="ADN00_00540"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003140">
        <property type="entry name" value="PLipase/COase/thioEstase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02230">
        <property type="entry name" value="Abhydrolase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Abhydrolase_2" evidence="1">
        <location>
            <begin position="24"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL81055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="216" mass="23599" checksum="00A6C95250CEBD65" modified="2016-01-20" version="1">MTQPYTLLENGWIYRIREPETGVSHEVIILVHGWTGDENSMEAFQHLFPKNAWLIAPRGIVTASPGGYGWTQTDLQSLSPFEQFSRPASEFRHHITALLQFLKTSTKNVNLAGFSQGAALIYTLLHLFPDWAKKAACMSGFLPPNAGSGSGALSKFKGQVLITHGTEDKMIPVQEAWRAADALKQAGVPVLTIIEPSGHKLGPDGAKGVKLFFNSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XMK7</accession>
    <name>A0A0P6XMK7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AcnX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_00715</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061031.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00715"/>
    <dbReference type="EnsemblBacteria" id="KPL81083">
        <property type="protein sequence ID" value="KPL81083"/>
        <property type="gene ID" value="ADN00_00715"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3541"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007506">
        <property type="entry name" value="AcnX_catalytic_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04412">
        <property type="entry name" value="AcnX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AcnX" evidence="1">
        <location>
            <begin position="1"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL81083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="431" mass="47634" checksum="5FB96E33B98EA4BC" modified="2016-01-20" version="1">MILTPEDQAILDGKQGEVLQKVMKSVVVYGETFGADHLVPITGSPHMVTSFGANTIQPYFDMLDELIGAGLQSKEPFTVDPRPMEYDRLNPGLVEKLAFNLIFGKQAAYEQQLKKLGLKDENSFTCTCYLPEVGNTPAKGDFLAWSESSAVVFANSVLGARTNRNSGGIDLMCDIIGKAPYFGLLTDEGRQATWLVEVKTSSKPNAQLLGSAIGMKVMEDVPYIVGMDGFLGTGLNPATEAYLKDMGAATASNGAVGLYHVENITPEAVESGRTLLKPGYQTYVIDDHELARVYQAYPLLWKNANTQPDYIFVGCPHLARHQLESWIEQLENQLRHHKANRLKIPVYLFTAPDIQKAFISEKPDTYQTLLSQQIHITSICPLMYMNNPLCGRKPIVTNSNKLRTYTTARFYLDEDVLQIAVTGKLPSRGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XMM8</accession>
    <name>A0A0P6XMM8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ATPase AAA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_08655</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000022">
        <property type="protein sequence ID" value="KPL77656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062597.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000022.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08655"/>
    <dbReference type="EnsemblBacteria" id="KPL77656">
        <property type="protein sequence ID" value="KPL77656"/>
        <property type="gene ID" value="ADN00_08655"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1446"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001374">
        <property type="entry name" value="R3H_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036867">
        <property type="entry name" value="R3H_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045735">
        <property type="entry name" value="Spore_III_AA_AAA+_ATPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01424">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19568">
        <property type="entry name" value="Spore_III_AA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00393">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82708">
        <property type="entry name" value="SSF82708"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51061">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="R3H" evidence="4">
        <location>
            <begin position="478"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="339"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL77656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="542" mass="60731" checksum="0A10CDF447985DC3" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XMV2</accession>
    <name>A0A0P6XMV2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_11380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063136.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11380"/>
    <dbReference type="EnsemblBacteria" id="KPL76553">
        <property type="protein sequence ID" value="KPL76553"/>
        <property type="gene ID" value="ADN00_11380"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="170"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="246" mass="27174" checksum="D1F79A28D9299BBF" modified="2016-01-20" version="1">MNSAQIFRTFGPVDARMVWRDSLLRSSLFLPVVMGLAMRVVVPPFVETISRLISFDLQPYAPMTLTYLMLMMMPSFAGMLVGMLLLDQRDDRTLTALQVTPLSLKGYLMYRLAVPTLLGFVMTLIAVPLSGLMTFSVSALLAAALLAAPLAPVFALVFAGLAANKVQGLAVMKTVGGIVELPIIGFFLPERWQPLFGVIPTYWPAKVFTLLQNGEAGAWLYALVGVAYQILLIWLLARRFHHQMTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XN64</accession>
    <name>A0A0P6XN64_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioredoxin reductase</fullName>
            <ecNumber evidence="3">1.8.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_08110</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>[thioredoxin]-dithiol + NADP(+) = [thioredoxin]-disulfide + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:20345"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.8.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="4">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-II pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.1.9" evidence="3"/>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77912.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062570.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08110"/>
    <dbReference type="EnsemblBacteria" id="KPL77912">
        <property type="protein sequence ID" value="KPL77912"/>
        <property type="gene ID" value="ADN00_08110"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.622"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004791">
        <property type="term" value="F:thioredoxin-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019430">
        <property type="term" value="P:removal of superoxide radicals"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008255">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_2_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005982">
        <property type="entry name" value="Thioredox_Rdtase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01292">
        <property type="entry name" value="TRX_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00573">
        <property type="entry name" value="PYRIDINE_REDOX_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2 3" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="5">
        <location>
            <begin position="21"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL77912.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="324" mass="35309" checksum="B227D5823153ED1E" modified="2016-01-20" version="1">MEFNLSNISSESNKQEKVHTSVLVLGSGPAGLSAALYAARAELNPVVLGGMEFGGQAALTHIIENYPGFPDGVGGSDLAELFKKQAERFGARFEFDVATEVDLSKRPFYLKSYNKEYLADTLIITTGASPNHLNVPGEKELTGRGVSYCATCDGWFFKDKDVAVVGGGDSALEEGLFLTRYAKSVTIIHRRDQLRAGAILQERAKKNEKMRFIWDSIVTRINGSEKVNSLNLKNVKTGEESDFPVDGVFIFIGHTPNTQLFKGQLEMDEKGYIVPDLLMRTSVPGVFAAGEINDPNYRQVITSAGMGAAAAIQATRFLEDHESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XNS5</accession>
    <name>A0A0P6XNS5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_14300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000034">
        <property type="protein sequence ID" value="KPL73739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL73739">
        <property type="protein sequence ID" value="KPL73739"/>
        <property type="gene ID" value="ADN00_14300"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL73739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="217" mass="26237" checksum="67053E991B4DA00C" modified="2016-01-20" version="1">MFQVQLPTNISQSGWHVAHIFDVKDRRTDYEYWDRKELLWRTARNIHPCNYFYIPKIDWQSYGGDPTVIAFFYEIFQQLYEPIWDEFLNLVNGQPLKQSRNPQTFHYSFPKDIKETAYSRQVKKSDTMQNRPNQESRSSFGYKEIYPYYRLCFKAEIIEPLNWDDEFCVITPEGSFAMSKRDFYETFPNVVKSLSYQRDKIYHYSVIPKKALKFKLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XPX6</accession>
    <name>A0A0P6XPX6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PTS maltose transporter subunit IIBC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05935</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062048.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05935"/>
    <dbReference type="EnsemblBacteria" id="KPL78772">
        <property type="protein sequence ID" value="KPL78772"/>
        <property type="gene ID" value="ADN00_05935"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00211">
        <property type="entry name" value="PTS_IIA_fru"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016152">
        <property type="entry name" value="PTrfase/Anion_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002178">
        <property type="entry name" value="PTS_EIIA_type-2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00359">
        <property type="entry name" value="PTS_EIIA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55804">
        <property type="entry name" value="SSF55804"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51094">
        <property type="entry name" value="PTS_EIIA_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PTS EIIA type-2" evidence="1">
        <location>
            <begin position="4"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="145" mass="15741" checksum="C760B25FF2F584CC" modified="2016-01-20" version="1">MLSKYLSPQAILLQVPVKDWKEAVEMGGALLVDTGKCEPRYVDAMVRAVQDLGPYMVLAPGLSLAHARPEDGALQVGMSIVSLSTPVDFGSEANDPVQLVISFCGIDHSSHIEMLKSLAEFLVVEENQNLLKSSNSIEEILKAFQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQ17</accession>
    <name>A0A0P6XQ17_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Flg_hook domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_17085</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Controls the length of the flagellar hook.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FliK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064262.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17085"/>
    <dbReference type="EnsemblBacteria" id="KPL71408">
        <property type="protein sequence ID" value="KPL71408"/>
        <property type="gene ID" value="ADN00_17085"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009424">
        <property type="term" value="C:bacterial-type flagellum hook"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001635">
        <property type="entry name" value="Flag_hook_Flik"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021136">
        <property type="entry name" value="Flagellar_hook_control-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038610">
        <property type="entry name" value="FliK-like_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02120">
        <property type="entry name" value="Flg_hook"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01007">
        <property type="entry name" value="FLGHOOKFLIK"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1005">Bacterial flagellum biogenesis</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flg_hook" evidence="6">
        <location>
            <begin position="297"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="34"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="133"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="225"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="374"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="337"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="41"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="59"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="138"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="239"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="374"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL71408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="418" mass="42917" checksum="2F9F7485C432A02B" modified="2016-01-20" version="1">MNILLLQGAQTAPPAVGPNAAASIASATSFQELLDQQIAKAPPERSEKPVREAKEQPSASRSEPAQRSESTSKAAAEDQPAGSVQAKDDQSKPGDEAPPTEEEAPQAEETALAGAGAVTAPIVPQDLVIDPAGEAASAGSAGSTTQIAEQMAGQIEASQTAPAAAQPGEAQPAVEQLAAAAPLVEEAAPQPVAAPQPTVEEMVQSTAGKDRVADEMLNVTAVKVESAPTAKVEAPAATPASASASQTAAEPADEGPSVTTAQQTQQAYAAQQPQAAQEPARMAEARGSEVVKQVAPQLEMMAKSGTRTLTMQLNPAELGQIDLRLTASGGTVRITMHASQAATNDLLESQLNQLRQNLANAGVQISDLNVGQQAGKSAWQQPQQRGGSSAYRHQEQPEAKPLPTRKASLQASNIDYTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XR13</accession>
    <name>A0A0P6XR13_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">M20_dimer domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_16015</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064047.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16015"/>
    <dbReference type="EnsemblBacteria" id="KPL72003">
        <property type="protein sequence ID" value="KPL72003"/>
        <property type="gene ID" value="ADN00_16015"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00758">
        <property type="entry name" value="ARGE_DAPE_CPG2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="2">
        <location>
            <begin position="173"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL72003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="389" mass="41264" checksum="336DE1E4D62C3EAB" modified="2016-01-20" version="1">MSIEKLQGAAAEEFIQFCQTLVKIPGCTGEERAVAEAVTAQCLSMPFDRVQTDALGNVIAVRKGAADGPLVLFDGHMDVVPVESAEEWQHDPHGAEIAEGKLWGRGAADTRASLAGMIWAAGSLSKSDFRGTLVMAATVCEENVTGAALSAVLDTVQPDVVVTGEPTALRLGVAQKGRMTLFLDAQGRSAHTSTPEAGENAVDKMLDALQRLRQMELPSDADLGRSLLVLTEIISDPYPNGFSVPHGCHARLIGRTLPGESRDQVLGRVQAALQGMNGVHFHMGQLEQRTYTGHVLRVEDFLPGWRNPPGDAWQTKIRAALQAAGLPGDLYHAPCGTNASASARRGVSSFIFGPGELSQAHTVDEGVLVEDVLLGELGFRAILAACLGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XRD4</accession>
    <name>A0A0P6XRD4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidyl-prolyl cis-trans isomerase</fullName>
            <ecNumber evidence="4">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_08025</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 3 4">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the FKBP-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77824">
        <property type="protein sequence ID" value="KPL77824"/>
        <property type="gene ID" value="ADN00_08025"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.605"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="5">
        <location>
            <begin position="20"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL77824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="173" mass="19390" checksum="36C9E0399A5B0824" modified="2016-01-20" version="1">MREWRLELNNKSVPTVIENDVVVTMDYELLVDGELIDSSQENGPIDFLQGHENIVPGLERELYGLKVGDSVSVTVSPEDGYGEYDDDAVIEVPRSEFPNDFTPEPGMELEVRDEENELHEATILDVTDDVVVLDFNDPLAGETLQFHVTILELRAATAEELEHGHVHDAGHEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XRH5</accession>
    <name>A0A0P6XRH5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Epimerase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_02985</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000013">
        <property type="protein sequence ID" value="KPL79403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061469.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000013.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79403">
        <property type="protein sequence ID" value="KPL79403"/>
        <property type="gene ID" value="ADN00_02985"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="335" mass="37304" checksum="7E642E9D8477C8C3" modified="2016-01-20" version="1">MRILILGGTQFVGRWMAQAAIDAGHQVTLFNRGQSNPHLFTQAEKLTGDRGGDLSALQGRTWDAVIDTSAYFPRHAAASADLLKDSIGLYLFVSSIAVYADFKQSGLHEGSEVGRLDDESVEVVNLKTYGPLKALCEREINRILPDRNVILRPCIVVGPHDNTDRFTWWLHRAAQGGEMFVPGGPEAPFQIIDARDLAAWAVRLLENGQTGTFNAAGLEEPVTLGDTLNAAREISGSDARFTWVSEDFFKTHKVSHWRELPFWLPTWDASYPGYFQIDNRKALAAGLTFRPLRETVADTLAWSQTLPADHAWRAGLTPQREEELLQAWRDFQASA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XS31</accession>
    <name>A0A0P6XS31_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000029">
        <property type="protein sequence ID" value="KPL75293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063476.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000029.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL75293">
        <property type="protein sequence ID" value="KPL75293"/>
        <property type="gene ID" value="ADN00_13110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL75293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="138" mass="14780" checksum="6A8ECD60A92BE1B0" modified="2016-01-20" version="1">MDFPVRRTSIPVSRPLRAVIHGMALAIVDLLAGMGALSLQRLAAGELSPLAIQIPAALVLTVLGFEAWCQLCQRSQGFKRLTPRGRWDAASIFAGGLVFGPLFFVSLVPSGLGGLAEMWGIQLGANLLAVLWACRRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XTI6</accession>
    <name>A0A0P6XTI6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MDMPI_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_06755</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000018">
        <property type="protein sequence ID" value="KPL78419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78419">
        <property type="protein sequence ID" value="KPL78419"/>
        <property type="gene ID" value="ADN00_06755"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034660">
        <property type="entry name" value="DinB/YfiT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024344">
        <property type="entry name" value="MDMPI_metal-binding"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11716">
        <property type="entry name" value="MDMPI_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109854">
        <property type="entry name" value="SSF109854"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MDMPI_N" evidence="1">
        <location>
            <begin position="3"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="140" mass="15704" checksum="394E2D37EC3A8055" modified="2016-01-20" version="1">MLERLREFAARATQADLCQPMPAGWTVSAVLAHLAFWDTRASTLMRQWQAEGITPSPIDVDVINEVTRPLCLAIEPRAALELMLRCAAEVDALIEASDPAFLRQMETDGQTVHLNRGQHRRTHLTEIYQALGWAPDAQQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUF1</accession>
    <name>A0A0P6XUF1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062051.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78775">
        <property type="protein sequence ID" value="KPL78775"/>
        <property type="gene ID" value="ADN00_05950"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="133" mass="15051" checksum="36FDB93F5B723627" modified="2016-01-20" version="1">MFFHRFFGRLISLILLLLLVFAGGNLLFRGAWAQGYAAGQGEMIAPAPVVIDLQNWIPTVLIIAGVALVLSITGALARYYFWKKMGGPEMFAKFRQAKFYGYGPMHHHFHRFHYGCPYAWGEVKDEPKPESEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-08-12" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUM0</accession>
    <name>A0A0P6XUM0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_06520</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062154.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78857">
        <property type="protein sequence ID" value="KPL78857"/>
        <property type="gene ID" value="ADN00_06520"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="432" mass="49626" checksum="F3131D81A7BAA394" modified="2016-01-20" version="1">MIFKIYHLTLLRPIQISMNVLAILPSVIPSTIIYTIKPLTDLHRRGMLKARIRLEFLTTRKDLEWADVVLFIRNYEWSLGWMLDELNKLQKPFLYDLDDNFFAVPLESSFGQYLNHPARKAMIERLLTQAALVRVYSKPLVEICSAYNPNVRLINGPFDWSLVTPRGDEEAVQGPVKIVYATSRSIDDNLGAVFFQALDQILEKHGDQVEVHFWGSNPFAGRQDERIFFHPFMRDYDQFVRAFSAGRYDIGLAPLINDIFHRSKTNIKYREYSACRIAGIYSNVDVYSDHIQHGRNGLLVENDTQSWFEAIDWLVAHPLERSQIAEAAYSDVLTRYSNQQFIDELYGHLQLARSLPVQPYQPQPGAESAAMSSMPATQAGKPLLAKILHKIRQAFVNGQIKAFFQTLSNYLKGLVHIILIQSRITLSGLHRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XWS5</accession>
    <name>A0A0P6XWS5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_00290</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060956.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00290"/>
    <dbReference type="EnsemblBacteria" id="KPL81021">
        <property type="protein sequence ID" value="KPL81021"/>
        <property type="gene ID" value="ADN00_00290"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001544">
        <property type="entry name" value="Aminotrans_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036038">
        <property type="entry name" value="Aminotransferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043132">
        <property type="entry name" value="BCAT-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043131">
        <property type="entry name" value="BCAT-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01063">
        <property type="entry name" value="Aminotran_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56752">
        <property type="entry name" value="SSF56752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL81021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="280" mass="31943" checksum="FEE4684D4D154ACD" modified="2016-01-20" version="1">MAQVWKLNGKYEILSEGELPISPDANLDQISKLLPGGAYTTFRTYDHYKIVSLENHFLRLEETAALAGKPIQLDYEKLRGTIREIVHRELTRELRIRITLDLQENPGLIYLSYEPLVTPAKELYETGASAETTLLERDNPKAKLTDFIIRSQELKSRLNQDLQEILMVNSSGEITEGLTSNFFGVLDNKIFTAEEGVLLGITRSALIEEAQKFGFEIVYKPVRVDELPRLEEAFITSTSRLVLPIREIDQQPIRNGIPGVVTKKLIELLKRRIVSEYEEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XWT6</accession>
    <name>A0A0P6XWT6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01845</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000007">
        <property type="protein sequence ID" value="KPL80037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01845"/>
    <dbReference type="EnsemblBacteria" id="KPL80037">
        <property type="protein sequence ID" value="KPL80037"/>
        <property type="gene ID" value="ADN00_01845"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="240" mass="26473" checksum="7141DACFD9A11D34" modified="2016-01-20" version="1">MRKAIKLPEHAPGQGFPEYALILALAVVILVLILNLLGVSTRELYCTVLTSLGVETALCESAYCQSAFESMEGWQSSQNQGWNIQNGNLCNTSNPYPNFLFNQCSQQNAPSDYVIKIDGATLNAGDGYGVFFRLQNYDNRPSGYIFQYDPGLGGAFAVRKWVNGNEINPPIALNRPPGYTWTGVPRDVEIHVKGNTYTAFVDGQQVLTFTDNTYMSGGVGLRTWDKTSVCMDDFSINPIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="38" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XWW4</accession>
    <name>A0A0P6XWW4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Aspartate 1-decarboxylase</fullName>
            <ecNumber evidence="9">4.1.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Aspartate alpha-decarboxylase</fullName>
        </alternativeName>
        <component>
            <recommendedName>
                <fullName evidence="9">Aspartate 1-decarboxylase beta chain</fullName>
            </recommendedName>
        </component>
        <component>
            <recommendedName>
                <fullName evidence="9">Aspartate 1-decarboxylase alpha chain</fullName>
            </recommendedName>
        </component>
    </protein>
    <gene>
        <name evidence="9" type="primary">panD</name>
        <name evidence="14" type="ORF">ADN00_00420</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>H(+) + L-aspartate = beta-alanine + CO2</text>
            <dbReference type="Rhea" id="RHEA:19497"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:57966"/>
            <dbReference type="EC" id="4.1.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9 10">
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </cofactor>
        <text evidence="9 10">Binds 1 pyruvoyl group covalently per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="9">Cofactor biosynthesis; (R)-pantothenate biosynthesis; beta-alanine from L-aspartate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Heterooctamer of four alpha and four beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="9 12">Is synthesized initially as an inactive proenzyme, which is activated by self-cleavage at a specific serine bond to produce a beta-subunit with a hydroxyl group at its C-terminus and an alpha-subunit with a pyruvoyl group at its N-terminus.</text>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the PanD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.11" evidence="9"/>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060979.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00420"/>
    <dbReference type="EnsemblBacteria" id="KPL81039">
        <property type="protein sequence ID" value="KPL81039"/>
        <property type="gene ID" value="ADN00_00420"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3477"/>
    <dbReference type="UniPathway" id="UPA00028">
        <property type="reaction ID" value="UER00002"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004068">
        <property type="term" value="F:aspartate 1-decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006523">
        <property type="term" value="P:alanine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06919">
        <property type="entry name" value="Asp_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00446">
        <property type="entry name" value="PanD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003190">
        <property type="entry name" value="Asp_decarbox"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21012">
        <property type="entry name" value="PTHR21012"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02261">
        <property type="entry name" value="Asp_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006246">
        <property type="entry name" value="Asp_decarbox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00223">
        <property type="entry name" value="panD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="1 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 9" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="6 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 9" id="KW-0566">Pantothenate biosynthesis</keyword>
    <keyword evidence="8 9 10" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9 10" id="KW-0704">Schiff base</keyword>
    <keyword evidence="5 9" id="KW-0865">Zymogen</keyword>
    <feature type="chain" id="PRO_5011837152" description="Aspartate 1-decarboxylase beta chain" evidence="9 13">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5011837153" description="Aspartate 1-decarboxylase alpha chain" evidence="9 13">
        <location>
            <begin position="25"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9 11">
        <location>
            <begin position="73"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with substrate; via pyruvic acid" evidence="9 10">
        <location>
            <position position="25"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="9 10">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9 11">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="modified residue" description="Pyruvic acid (Ser)" evidence="9 12">
        <location>
            <position position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR006246-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR006246-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR006246-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR006246-5"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KPL81039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="130" mass="14020" checksum="7B0D401B637DED12" modified="2016-01-20" version="1">MMRNLLLSKIHRATVTGSDLNYIGSITIDQDLMNAAGMLAWEKVQVVDLDNGARLETYVIPGEAGKGDIQLNGAAARLVSKGDIVIIMAYGWLTADEAQSHSPKVVLVNDQNQIQEVRALPSHPDPDAIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XXX1</accession>
    <name>A0A0P6XXX1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">HNH endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_07050</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062278.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07050"/>
    <dbReference type="EnsemblBacteria" id="KPL78228">
        <property type="protein sequence ID" value="KPL78228"/>
        <property type="gene ID" value="ADN00_07050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3228"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00085">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029471">
        <property type="entry name" value="HNH_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14279">
        <property type="entry name" value="HNH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00507">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HNHc" evidence="1">
        <location>
            <begin position="70"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="167" mass="19066" checksum="BE29A62BA513F39D" modified="2016-01-20" version="1">MHESVLVLNANFEPINICSTRRAVSLMLAEKASLIANGRGYIRTARLKIPAPSVIRLAHMVHRPRPHLRLTRREVLRRDNFTCQYCGRRAEELTIDHIIPRRLGGRLTWDNVVTACAPCNHKKGGKTLEEAGMRLLRQPKEPPSSAEYRFGRSGASFVEWEPFLQGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XY66</accession>
    <name>A0A0P6XY66_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">D-alanine--D-alanine ligase</fullName>
            <ecNumber evidence="7">6.3.2.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">D-Ala-D-Ala ligase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">D-alanylalanine synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ddl</name>
        <name evidence="11" type="ORF">ADN00_07405</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Cell wall formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + 2 D-alanine = ADP + D-alanyl-D-alanine + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:11224"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57416"/>
            <dbReference type="ChEBI" id="CHEBI:57822"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.2.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="8">Binds 2 magnesium or manganese ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the D-alanine--D-alanine ligase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.4" evidence="7"/>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78283.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062345.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07405"/>
    <dbReference type="EnsemblBacteria" id="KPL78283">
        <property type="protein sequence ID" value="KPL78283"/>
        <property type="gene ID" value="ADN00_07405"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3304"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008716">
        <property type="term" value="F:D-alanine-D-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00047">
        <property type="entry name" value="Dala_Dala_lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000291">
        <property type="entry name" value="D-Ala_lig_Van_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005905">
        <property type="entry name" value="D_ala_D_ala"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011095">
        <property type="entry name" value="Dala_Dala_lig_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011127">
        <property type="entry name" value="Dala_Dala_lig_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07478">
        <property type="entry name" value="Dala_Dala_lig_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01820">
        <property type="entry name" value="Dala_Dala_lig_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039102">
        <property type="entry name" value="Ddl/VanB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01205">
        <property type="entry name" value="D_ala_D_alaTIGR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00843">
        <property type="entry name" value="DALA_DALA_LIGASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00844">
        <property type="entry name" value="DALA_DALA_LIGASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7" id="KW-0133">Cell shape</keyword>
    <keyword evidence="6 7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 7 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="10">
        <location>
            <begin position="148"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR039102-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL78283.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="374" mass="41488" checksum="E3D16B96619C8AD7" modified="2016-01-20" version="1">MKTDRKIHIGVLFGGRSGEHEVSLMSARSVLSVLDPQKYEIIRVGITHQGEWFAGENALEALQNGDTSGLTRVTLLPQPGLNQLYAIEEQDGRATLRPYAPLDVVFPVLHGTFGEDGTLQGLLEMADLAYVGGGVLASSVGMDKALFKEILRSRGIRVVPSLTFTRRQIQTDIEAVLDQAETISHYPLFVKPVNLGSSVGVSKCRDRRQLRLGLENAARYDRRILVELGVNAREIEVSVLGNDQPIASIPGEILPAGDFYSYESKYIDERSELVIPAPLDEITMEEIRRIAVEVYRAMDGAGMARIDFLLDRETGIAYVNEANTIPGFTKISMYPKLWEASGLSYQELVDQLIELAFDRKKDRDQTIREYGSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XYM4</accession>
    <name>A0A0P6XYM4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_07760</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062409.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78337">
        <property type="protein sequence ID" value="KPL78337"/>
        <property type="gene ID" value="ADN00_07760"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="123"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="193"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="230"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="273"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="349"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="384"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="493"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="566"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="602"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="628"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="682"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="756"/>
            <end position="774"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="795"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="194"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="562"/>
            <end position="774"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL78337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="1287" mass="140517" checksum="F7A177DBE75C5C9A" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XZ39</accession>
    <name>A0A0P6XZ39_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_06760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000018">
        <property type="protein sequence ID" value="KPL78420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062221.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000018.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06760"/>
    <dbReference type="EnsemblBacteria" id="KPL78420">
        <property type="protein sequence ID" value="KPL78420"/>
        <property type="gene ID" value="ADN00_06760"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025671">
        <property type="entry name" value="HXXEE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13787">
        <property type="entry name" value="HXXEE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="188" mass="20717" checksum="006AC8F2BB4127C5" modified="2016-01-20" version="1">MTAAPAPLPVDIANLMWLLPVVFMLHDFEEIIMIKPWLARGLPAIQERYPRLARLIAGSTGGLSQPAFALIVAEEFVIISLLTWLAVAASNLTLWLALLMGFFVHLLMHIGQFIAARAYVPVILTSPPAAAYCLYAAWQINQLYPIDWPKIWLWSAAVAALIVINLAAAVRLAKGFDAWLQTHFSAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y0H1</accession>
    <name>A0A0P6Y0H1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_06220</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062099.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06220"/>
    <dbReference type="EnsemblBacteria" id="KPL78813">
        <property type="protein sequence ID" value="KPL78813"/>
        <property type="gene ID" value="ADN00_06220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="5"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="45"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="82"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="181"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="229"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="263"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="300"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL78813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="345" mass="37418" checksum="6D86C9A6493C2F06" modified="2016-01-20" version="1">MNKKVISGVTGIFVAMLLGALIMLFQNYDPLETYGALFSYSLGDFYSLATTLQNSVPLILTGLSASLAFASGPVNLGQPGQFLMGALLVTIGGLYVDLPPVLMIPFLILLAMLGGALWSGVAALLRQWFGMSEFITTLMLNMIADFFTYWAITYPFYDQSAFSPMTPLINRSGWLPEFGEFNSSVIVMLLAFAGVWFIFTRFTAGYEWRITGQNSLFARLGGCDINKNYLTVMLVTGALAGLAGGLVIMAGPHRFLKGIGANYAWDGVMIAMVANNGLIATVLYGLFFATLQTGALGMELITAVPSEFIQVLQAAIVLIIVAGREYLDIFMDRTAARRKAKERSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y299</accession>
    <name>A0A0P6Y299_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Galactose isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_04045</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LacAB/RpiB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061679.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04045"/>
    <dbReference type="EnsemblBacteria" id="KPL79060">
        <property type="protein sequence ID" value="KPL79060"/>
        <property type="gene ID" value="ADN00_04045"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.164"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016861">
        <property type="term" value="F:intramolecular oxidoreductase activity, interconverting aldoses and ketoses"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003500">
        <property type="entry name" value="RpiB_LacA_LacB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036569">
        <property type="entry name" value="RpiB_LacA_LacB_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30345">
        <property type="entry name" value="PTHR30345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02502">
        <property type="entry name" value="LacAB_rpiB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005384">
        <property type="entry name" value="RpiB_LacA_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89623">
        <property type="entry name" value="SSF89623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00689">
        <property type="entry name" value="rpiB_lacA_lacB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="145" mass="15789" checksum="F0DFA0E03B15BCCA" modified="2016-01-20" version="1">MRIAVGADEQLDVAQYLLDYLRELGHDVDWFGPSVGESQPWPQVAEQVAWSVASGEAQMGVALCWTGTGVCIAANKVRGIRAALCVDAETARGARLWNDANVLCLSMRLASRPVAKEIVDAWLVTDYLSNPTDDACLALIRKLEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y7P0</accession>
    <name>A0A0P6Y7P0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">DNA repair protein RecN</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4 5">Recombination protein N</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_08640</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">May be involved in recombinational repair of damaged DNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the RecN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000022">
        <property type="protein sequence ID" value="KPL77653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062594.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000022.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08640"/>
    <dbReference type="EnsemblBacteria" id="KPL77653">
        <property type="protein sequence ID" value="KPL77653"/>
        <property type="gene ID" value="ADN00_08640"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1441"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004604">
        <property type="entry name" value="DNA_recomb/repair_RecN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11059">
        <property type="entry name" value="PTHR11059"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003128">
        <property type="entry name" value="RecN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00634">
        <property type="entry name" value="recN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMC_N" evidence="7">
        <location>
            <begin position="2"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="169"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00033408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR003128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02463"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL77653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="578" mass="64104" checksum="F1AA2D5FFC662DF0" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y823</accession>
    <name>A0A0P6Y823_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Carb-bd_dom_fam9 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_07930</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062452.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07930"/>
    <dbReference type="EnsemblBacteria" id="KPL77808">
        <property type="protein sequence ID" value="KPL77808"/>
        <property type="gene ID" value="ADN00_07930"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010502">
        <property type="entry name" value="Carb-bd_dom_fam9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06452">
        <property type="entry name" value="CBM9_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133398" description="Carb-bd_dom_fam9 domain-containing protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="Carb-bd_dom_fam9" evidence="2">
        <location>
            <begin position="115"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="309" mass="33082" checksum="85BB70FF1DA1A5C2" modified="2016-01-20" version="1">MKKNSRVLAAIGILILVSLACTAPIALPGGGDEEPTPNLTMTALFSVPELATSTSAPVVVVTNTPVVSTATAIPSATALPPTATSTNTSAPTATSIPARGMVVSAAYLSGGIDLDGVWDEWNTKAYPMKNVVYGKSNWTGEEDLEGSYRIGWNNSYLFIAVKVRDEQYEQHASGADMYKGDSIELLLDTNLYDDFYTTELSPDDHQLGISAGKNGTDDGEEVYLWFPTGKTGLRDSVQIGKSLEDGVYRIEAAIPWSVFGITPTSGMHLGFALSASDNDVSWDEQQTMVSSIATRRLTNPTTWGELILQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YAG5</accession>
    <name>A0A0P6YAG5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glyco_trans_2-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_06470</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062144.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78851">
        <property type="protein sequence ID" value="KPL78851"/>
        <property type="gene ID" value="ADN00_06470"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1797"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="90"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="398" mass="45089" checksum="155CD8BC3103EA78" modified="2016-01-20" version="1">MPSVVLELEFTQLPDKLTDLDRYQKAFILLKYAGYPVAKLWLPVNQGMVSRAQLEDAILKNCGEAFWQRWAEDLFQINENHPPKFSLTTTVAICTRDRPEDLRTCLQGLMLLPDDGQEILVIDNCPSSDATARVVAAFPRARYVLEKRRGLDVARNRALREARGEIVAFIDDDARPDPRWLRALLANFIDPQVMCVTGLTMPMELETEAQEFFEHYGGFGRGFQRREFARLTFNPLFGGQVGAGANMALRRSVVEQVGLFDEALDAGTATHSGGDADMCSQILRSGYKIIYEPAALNWHRHRRSLPELHKVIYGYGVGVYAMLTKEFLLNRRVGVVRVMWGWLRYGQLPGLFKALFNPSASPLPAAFYWDELRGCLAGPKAYLKARRELREQLESEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YAV7</accession>
    <name>A0A0P6YAV7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Lysine methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_03915</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061657.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03915"/>
    <dbReference type="EnsemblBacteria" id="KPL79043">
        <property type="protein sequence ID" value="KPL79043"/>
        <property type="gene ID" value="ADN00_03915"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003616">
        <property type="entry name" value="Post-SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00856">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00317">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SSF82199"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50868">
        <property type="entry name" value="POST_SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SET" evidence="4">
        <location>
            <begin position="11"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="Post-SET" evidence="5">
        <location>
            <begin position="125"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL79043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="172" mass="19757" checksum="B72EC71599CD2C6F" modified="2016-01-20" version="1">MESDCHSYLNPKLEVRAFPNKGGYGIFAREAVQAGELVCMWGGSIVTHDQLQTLPEDVVSHSIQVEEFLYQVQPWEHFDPADYFNHCCDPNAGLSSPISLVAIRDIQPDEEVCFDYAMSDSSDYDQFECMCASPRCRKTITGKDWQIPELQERYRGYFSPYLQRRIDKLRAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YB72</accession>
    <name>A0A0P6YB72_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_04805</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061819.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04805"/>
    <dbReference type="EnsemblBacteria" id="KPL79171">
        <property type="protein sequence ID" value="KPL79171"/>
        <property type="gene ID" value="ADN00_04805"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="131" mass="14317" checksum="2D604DB17BAA6B56" modified="2016-01-20" version="1">MTTSEERMKILNMIQEGKISAEEGMQLLNALDQVDRKAAKAEKADKVSGGPAAARFFRVMVTDVDSGKTRVNVRLPISVVMAGAKMGARFSPEVEGLDIQQLMKMVESGTTGKIVDVFDDQDGEHVEVFIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YBU3</accession>
    <name>A0A0P6YBU3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cation-transporting ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_02550</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000012">
        <property type="protein sequence ID" value="KPL79417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061392.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000012.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79417">
        <property type="protein sequence ID" value="KPL79417"/>
        <property type="gene ID" value="ADN00_02550"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="34"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="63"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="222"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="253"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="607"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="675"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="739"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="769"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="domain" description="Cation_ATPase_N" evidence="8">
        <location>
            <begin position="6"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL79417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="802" mass="88971" checksum="3101D0AA02621B5E" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YEK9</accession>
    <name>A0A0P6YEK9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MFS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_01365</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061167.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80524">
        <property type="protein sequence ID" value="KPL80524"/>
        <property type="gene ID" value="ADN00_01365"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="110"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="174"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="218"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="251"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="284"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="308"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="341"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="368"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="16"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL80524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="395" mass="41949" checksum="00E99B27944AB335" modified="2016-01-20" version="1">MEEIRSAVPEKTTEELFQAANVSAFASAHAMHDTFPAFLPSLAPLLIEKFSLSNTQVGLFTACLRLPSMLQPLLGHLSDRRDLRWIAILTPALTATAMSLLGIAPGYTAILVLLLVAGLSSAAFHSVAPAMAGQVSGSQLGRGMSYWMVSGELGRTLGPLIAVGAISWLTLPGLPFTMLMGWAASFILYFRLRAIPMNAMQASEGLPWRGALRQMKPVLLPLIGLMVMRSMLENAMAIYLPVYLTQKGASLWLAGASLTIYEAAGLFGALLGGSLSDRLGRKKMIMFSIMTAPLLTGAFVLAPSAARLPLLLLMGFSILCVNPPMMALIQESAPQNRAFSLGVFLGFNFLIGSLASIVAGALGDTFGLTAAFASSAGLYLLGAPMVLFLPRTPKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GL42</accession>
    <name>A0A0N8GL42_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glutamine--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.18</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Glutaminyl-tRNA synthetase</fullName>
            <shortName evidence="8">GlnRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">glnS</name>
        <name evidence="12" type="ORF">ADN00_17345</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-glutamine + tRNA(Gln) = AMP + diphosphate + L-glutaminyl-tRNA(Gln)</text>
            <dbReference type="Rhea" id="RHEA:20121"/>
            <dbReference type="Rhea" id="RHEA-COMP:9662"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.18"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.18" evidence="8"/>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064312.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17345"/>
    <dbReference type="EnsemblBacteria" id="KPL71450">
        <property type="protein sequence ID" value="KPL71450"/>
        <property type="gene ID" value="ADN00_17345"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.533"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004819">
        <property type="term" value="F:glutamine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006425">
        <property type="term" value="P:glutaminyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006424">
        <property type="term" value="P:glutamyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.240.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00126">
        <property type="entry name" value="Gln_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004514">
        <property type="entry name" value="Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022861">
        <property type="entry name" value="Gln_tRNA_ligase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000924">
        <property type="entry name" value="Glu/Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020058">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020059">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_codon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020056">
        <property type="entry name" value="Rbsml_L25/Gln-tRNA_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011035">
        <property type="entry name" value="Ribosomal_L25/Gln-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00749">
        <property type="entry name" value="tRNA-synt_1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03950">
        <property type="entry name" value="tRNA-synt_1c_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00987">
        <property type="entry name" value="TRNASYNTHGLU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50715">
        <property type="entry name" value="SSF50715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00440">
        <property type="entry name" value="glnS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1c" evidence="10">
        <location>
            <begin position="28"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="domain" description="tRNA-synt_1c_C" evidence="11">
        <location>
            <begin position="339"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="8">
        <location>
            <begin position="34"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="8">
        <location>
            <begin position="267"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="35"/>
            <end position="37"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="41"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="67"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="260"/>
            <end position="261"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="268"/>
            <end position="270"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KPL71450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="561" mass="64764" checksum="F81B8D821EA2D8B2" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GLB0</accession>
    <name>A0A0N8GLB0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_15965</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL71994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064037.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15965"/>
    <dbReference type="EnsemblBacteria" id="KPL71994">
        <property type="protein sequence ID" value="KPL71994"/>
        <property type="gene ID" value="ADN00_15965"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3626"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003797">
        <property type="entry name" value="DegV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043168">
        <property type="entry name" value="DegV_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02645">
        <property type="entry name" value="DegV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00762">
        <property type="entry name" value="DegV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51482">
        <property type="entry name" value="DEGV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL71994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="285" mass="31053" checksum="F5787207FDACB0B7" modified="2016-01-20" version="1">MSSNVTILTDSSAYLPQELVDQHPIDVIPLTLLWGDAVYRDGVDIKADTFYEKLAHSDTLPSTSQTSVHEYEEAYRRLLDAGQDVLVLPISGGLSASVESARQAKINLKTDRVEVMETRLVSMALGFQVLTVARAAQAGASLAECKTIAKKAYDHIGVYFSVDTLEFLHRGGRINTAKRLMGTALNLKPILEIRDGKIEAVGSVISQRKAMDRLVQLVESRIGGRKPVRLSVFHAGIPEIASNFKKRVDKHFNPVESILTFVSPVVGAHVGPGTISLAFMAGDIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GLX8</accession>
    <name>A0A0N8GLX8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AAA_12 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_14295</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000034">
        <property type="protein sequence ID" value="KPL73738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063709.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000034.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14295"/>
    <dbReference type="EnsemblBacteria" id="KPL73738">
        <property type="protein sequence ID" value="KPL73738"/>
        <property type="gene ID" value="ADN00_14295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd18808">
        <property type="entry name" value="SF1_C_Upf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045055">
        <property type="entry name" value="DNA2/NAM7-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041679">
        <property type="entry name" value="DNA2/NAM7-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10887">
        <property type="entry name" value="PTHR10887"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13087">
        <property type="entry name" value="AAA_12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_12" evidence="1">
        <location>
            <begin position="349"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL73738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="581" mass="64712" checksum="12DCE719A3B23BB3" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GM25</accession>
    <name>A0A0N8GM25_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ferritin</fullName>
            <ecNumber evidence="1">1.16.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_14000</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Iron-storage protein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>4 Fe(2+) + 6 H2O + O2 = 12 H(+) + 4 iron(III) oxide-hydroxide</text>
            <dbReference type="Rhea" id="RHEA:11972"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
            <dbReference type="ChEBI" id="CHEBI:78619"/>
            <dbReference type="EC" id="1.16.3.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the ferritin family. Prokaryotic subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.16.3.2" evidence="1"/>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063650.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000033.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14000"/>
    <dbReference type="EnsemblBacteria" id="KPL74114">
        <property type="protein sequence ID" value="KPL74114"/>
        <property type="gene ID" value="ADN00_14000"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008199">
        <property type="term" value="F:ferric iron binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:cellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006826">
        <property type="term" value="P:iron ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01055">
        <property type="entry name" value="Nonheme_Ferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001519">
        <property type="entry name" value="Ferritin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009040">
        <property type="entry name" value="Ferritin-like_diiron"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008331">
        <property type="entry name" value="Ferritin_DPS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041719">
        <property type="entry name" value="Ferritin_prok"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11431">
        <property type="entry name" value="PTHR11431"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00210">
        <property type="entry name" value="Ferritin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50905">
        <property type="entry name" value="FERRITIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="1" id="KW-0409">Iron storage</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ferritin-like diiron" evidence="2">
        <location>
            <begin position="1"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU361145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL74114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="166" mass="18945" checksum="41FF0D60411CCD3E" modified="2016-01-20" version="1">MLISKELEAAINAQIGNELGASHQYLSIAAYFEGRSLREFGKFFFAQSEEEREHALKFLNYLLEVGAEVKIPAIAAPKPTFDSAEEAVQAALTWEKEVTRQIYGLVEIALKDKDYISQNFLNWYVKEQLEEISSMETLLALVKMAGSNLLMLEPRLHELREEEDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GM28</accession>
    <name>A0A0N8GM28_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_14150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74138">
        <property type="protein sequence ID" value="KPL74138"/>
        <property type="gene ID" value="ADN00_14150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="150" mass="16226" checksum="A9DB241C712B7A75" modified="2016-01-20" version="1">MMNGIQGAGGPPPMGGMGGMRGPQQLSEEQKQTVQDLLEEYEEEEITTEDAKELFEAFKEAGIRGPGLREAIEEAGFNADELFSKAHDGQKPPAPPSGGRQVNSASLQSLQSILEQYDLENMDQEQANQLYSQLNQAGLLRAGGMIDITT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMK4</accession>
    <name>A0A0N8GMK4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_12960</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL75546">
        <property type="protein sequence ID" value="KPL75546"/>
        <property type="gene ID" value="ADN00_12960"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL75546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="89" mass="10157" checksum="1B1FDD41FE4DBC59" modified="2016-01-20" version="1">MSKLLRVGIPNKSWSCGITFLLKKSCSNMESQVGYGFKALLMDEGILLLIIYGHSMIRKDFSLFIQELSREKKFIRSVLHLPSLINIPI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GN21</accession>
    <name>A0A0N8GN21_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Y1_Tnp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062817.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09780"/>
    <dbReference type="EnsemblBacteria" id="KPL76882">
        <property type="protein sequence ID" value="KPL76882"/>
        <property type="gene ID" value="ADN00_09780"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2413"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002686">
        <property type="entry name" value="Transposase_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036515">
        <property type="entry name" value="Transposase_17_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01797">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01321">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143422">
        <property type="entry name" value="SSF143422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Y1_Tnp" evidence="1">
        <location>
            <begin position="9"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="182" mass="21466" checksum="CD7B827187AF1F04" modified="2016-01-20" version="1">MPNYHRAWSPGGTYFFTLVTHQRRPIFTEEMARQTLHQAIMVGMQRVGDFQVDAFCLLPDHLHCIWTLPENDSDYATRWKVIKAWFSRTYRKQGGKSAAINASMAQKGELGIWQRRYWEHFIRDLDDLKRHIDYIHYNPVKHGLVQSVADWPWSTFHRFVKDGFYPADRGRGDASSFAVMEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GN77</accession>
    <name>A0A0N8GN77_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_09405</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062736.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09405"/>
    <dbReference type="EnsemblBacteria" id="KPL77330">
        <property type="protein sequence ID" value="KPL77330"/>
        <property type="gene ID" value="ADN00_09405"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL77330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="588" mass="67164" checksum="070D5B3E1EE5FAC6" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNV6</accession>
    <name>A0A0N8GNV6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Adenylyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_04750</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061808.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04750"/>
    <dbReference type="EnsemblBacteria" id="KPL79162">
        <property type="protein sequence ID" value="KPL79162"/>
        <property type="gene ID" value="ADN00_04750"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.314"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008641">
        <property type="term" value="F:ubiquitin-like modifier activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045886">
        <property type="entry name" value="ThiF/MoeB/HesA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000594">
        <property type="entry name" value="ThiF_NAD_FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035985">
        <property type="entry name" value="Ubiquitin-activating_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10953">
        <property type="entry name" value="PTHR10953"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00899">
        <property type="entry name" value="ThiF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69572">
        <property type="entry name" value="SSF69572"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ThiF" evidence="1">
        <location>
            <begin position="12"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="251" mass="27150" checksum="25F92B765297C2E0" modified="2016-01-20" version="1">MESLSEHEKTRYARHLILPEIGLEGQQKLKAASVLVVGAGGLGSTICMFLAASGVGRIGVIDADTVDLSNLQRQVIHTTPRLGMPKAESAREQMLAINPEIEVAAITQRFTAENAHALAEGYQIFVDGTDNFATRLLINDLAVQTQRPFVYGAIYHFEGQASVFDASRGPCYRCLFPGQPPRDEAGAPPNGIFTPLPGTIATLEASETIKLITGVGEPLIGRLLLYNALEMTFETIHLQKQPNCPVCGQHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GP65</accession>
    <name>A0A0N8GP65_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cro/Cl family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01830</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000007">
        <property type="protein sequence ID" value="KPL80034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061257.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000007.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01830"/>
    <dbReference type="EnsemblBacteria" id="KPL80034">
        <property type="protein sequence ID" value="KPL80034"/>
        <property type="gene ID" value="ADN00_01830"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="3"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="62" mass="7215" checksum="580E284717607A85" modified="2016-01-20" version="1">MKLRLARIEKNLNQQELADLVEVTRQTIGLIEKGSYNPTLNLCIKIAKALDRTLDELFWEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GPD1</accession>
    <name>A0A0N8GPD1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Oligoendopeptidase F</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_01585</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the peptidase M3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061208.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80562">
        <property type="protein sequence ID" value="KPL80562"/>
        <property type="gene ID" value="ADN00_01585"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1076"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1370.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013647">
        <property type="entry name" value="OligopepF_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042088">
        <property type="entry name" value="OligoPept_F_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045090">
        <property type="entry name" value="Pept_M3A_M3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001567">
        <property type="entry name" value="Pept_M3A_M3B_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011977">
        <property type="entry name" value="Pept_M3B_clade3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804">
        <property type="entry name" value="PTHR11804"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01432">
        <property type="entry name" value="Peptidase_M3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08439">
        <property type="entry name" value="Peptidase_M3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02290">
        <property type="entry name" value="M3_fam_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1 6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase_M3_N" evidence="8">
        <location>
            <begin position="117"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M3" evidence="7">
        <location>
            <begin position="199"/>
            <end position="574"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL80562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="594" mass="67779" checksum="931D294706D1E5C6" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GPJ4</accession>
    <name>A0A0N8GPJ4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RNA polymerase sigma factor SigA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">sigA</name>
        <name evidence="9" type="ORF">ADN00_00600</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Interacts transiently with the RNA polymerase catalytic core.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the sigma-70 factor family. RpoD/SigA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061012.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00600"/>
    <dbReference type="EnsemblBacteria" id="KPL81066">
        <property type="protein sequence ID" value="KPL81066"/>
        <property type="gene ID" value="ADN00_00600"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3515"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00963">
        <property type="entry name" value="Sigma70_RpoD_SigA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009042">
        <property type="entry name" value="RNA_pol_sigma70_r1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007624">
        <property type="entry name" value="RNA_pol_sigma70_r3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007127">
        <property type="entry name" value="RNA_pol_sigma_70_r1_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042189">
        <property type="entry name" value="RNA_pol_sigma_70_r1_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028630">
        <property type="entry name" value="Sigma70_RpoD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03979">
        <property type="entry name" value="Sigma70_r1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00140">
        <property type="entry name" value="Sigma70_r1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04539">
        <property type="entry name" value="Sigma70_r3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00716">
        <property type="entry name" value="SIGMA70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RNA_pol_sigma70" evidence="8">
        <location>
            <begin position="361"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="6">
        <location>
            <begin position="362"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="65"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-2" evidence="6">
        <location>
            <begin position="168"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-3" evidence="6">
        <location>
            <begin position="247"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Sigma-70 factor domain-4" evidence="6">
        <location>
            <begin position="336"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Interaction with polymerase core subunit RpoC" evidence="6">
        <location>
            <begin position="192"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="68"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL81066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="402" mass="46084" checksum="D4F2BB861A55977D" modified="2016-01-20" version="1">MENDLIGVVEDEEYPAIARLIELGRQKSYVTIDDILHFFPEAEQDVEQLEEAFAALMSAGIPYLEDVSAEEPPEDELDLESEKEHEEEDDDRSPDDLAHIDTDDTIGLYLKEVSRVPLLTAEEEVELAQRIERGRMAREELARGNVSTNRRVELRALIEDGWAAREHLITANSRLVISVAKKYMGRGVPFLDLIQEGNIGLIRATKKFDYRRGHKFSTYATWWIRQAVTRAIADQGRTIRVPVHMGDQINKLLRVQHQLTQRLGREPAVEELAKSLDVSPKKVENMIQVARRPLSLETPTDDEEDSVLGDFIEDNEALAPDESATFNLLRQHLEEVLNTLPPREVRILQLRYGLLDGQAYTLEEVGRKMGVTRERVRQIEAQALSRLRHPVIRRKLRDYLGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WMS6</accession>
    <name>A0A0P6WMS6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_18900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064599.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70112">
        <property type="protein sequence ID" value="KPL70112"/>
        <property type="gene ID" value="ADN00_18900"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="46"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL70112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="178" mass="19520" checksum="51DAC24E1A078A9C" modified="2016-01-20" version="1">MLSKRIFDFDADDGKSGGNTQEDNETFDAWLEKQDSSVKGLYESHVANLKSALESERTSRKDAERQLRELAVQAGKGSEAEKKLTEMADKLAEATRRATFYEKAPGAGVRNVVAAYKLAMADGIFDGDKVDFKKLQEAYPELFGENEPPPGNAGEGNEKIGLPKKGMNQFIRAAAGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WQ47</accession>
    <name>A0A0P6WQ47_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cysteine desulfurase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">sufC</name>
        <name evidence="6" type="ORF">ADN00_15340</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily. Ycf16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063914.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15340"/>
    <dbReference type="EnsemblBacteria" id="KPL72200">
        <property type="protein sequence ID" value="KPL72200"/>
        <property type="gene ID" value="ADN00_15340"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.770"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03217">
        <property type="entry name" value="ABC_FeS_Assembly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010230">
        <property type="entry name" value="FeS-cluster_ATPase_SufC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43204">
        <property type="entry name" value="PTHR43204"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01978">
        <property type="entry name" value="sufC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="4"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL72200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="254" mass="28226" checksum="91381E53E56E3DCC" modified="2016-01-20" version="1">MADLEIRNLHVRIDETEILKGLNLKINKGEVHAIMGPNGTGKSTLAYTLMGHPGYEVTDGEILFKGQDLLELEPNERSVLGMFLAFQYPVAIPGVTLANFLRSALNARRKAVNPEDKGIPVPEFRKFLKAKMDLLKMDHSFAGRYLNDGFSGGEKKRAEILQMATLQPEIAILDETDSGLDIDALRIVSEGVNTLRGPEMGVLVITHYQRILNYIKPDYVHIMLAGQIVESGGADLALHLEEHGYDLLREKYTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WQD0</accession>
    <name>A0A0P6WQD0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_15720</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063981.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72264">
        <property type="protein sequence ID" value="KPL72264"/>
        <property type="gene ID" value="ADN00_15720"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="62" mass="6907" checksum="0C2125BFA49C63C3" modified="2016-01-20" version="1">MGVKEALKNIRETEALEHIAERLDSIDQRLERLEKALSSKTGKTVKKDEEKPGSDNESEPAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WR42</accession>
    <name>A0A0P6WR42_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_16745</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064198.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16745"/>
    <dbReference type="EnsemblBacteria" id="KPL71356">
        <property type="protein sequence ID" value="KPL71356"/>
        <property type="gene ID" value="ADN00_16745"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="22"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL71356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="205" mass="23201" checksum="5A9420FB1234AF48" modified="2016-01-20" version="1">MTHYPKLSGQLCYLSPCQVEDVEKWEAWFNDLEVSLPLGDEAYIPMSEEKMAEELRAALLHHAHIFSIIHKRTGELIGRCILFNIDMVNQTAMLGLVIGEKGYWGKGYGREALRLLLDYGFNLLNLNNIMVGVFSFNHRAVRSYRALGFQEIGRRREARLVAGKRYDVILLDLLAEEFRAANAGWGVATLLPSAGTARDAERESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WRB7</accession>
    <name>A0A0P6WRB7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_17390</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71456.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL71456">
        <property type="protein sequence ID" value="KPL71456"/>
        <property type="gene ID" value="ADN00_17390"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.542"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="200"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="224"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="256"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="300"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL71456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="355" mass="38262" checksum="3B4ABF8B72502798" modified="2016-01-20" version="1">MKRLFWNSEGRRLAMFWRLLFGFGLYMVFIFILQAIIGAAGVIVVMATGGYSLESFTSPGFAMQFAAQLQAMPVFTLLISVSTLIGSVLAIFVAGRAFDRRRFADFGLRFKPLWWSDFAFGLALGAVLMAFIFLVEWLMGWVTITAEQLAAQAGVALGVGLLVAAIRYICVGIYEELLSRGYMLRNLGEGFKNLGISPKLAILIGYLLSSVVFGLMHANNPNATLMSTINLMVAGLFLGLGYILTGELGISIGVHMTWNFFQGNVFGFPVSGLQSGASIINIQQSGPVVWTGGAFGPEAGIIGLLAMGLGCLLMVLYVKARHGKAGICEEIAQYAPRVKKTEVAAAPIAEEPTQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WSN5</accession>
    <name>A0A0P6WSN5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_16035</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064051.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72005">
        <property type="protein sequence ID" value="KPL72005"/>
        <property type="gene ID" value="ADN00_16035"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="220"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="268" mass="30137" checksum="9C3FB32A7FD8ADA1" modified="2016-01-20" version="1">MHTSHSLISFPSTLDQTPWFSALLSLLPFVAAGSLRIMVSFQPGWSPKEGSLLYSVYLLLCTLALTSGLVLGAVKKSPRWLYPYPVLLAFSSYILRLYLGYLLPVKINLQSSFFLSLLIILIFLWLPPFHAFYQNIRQDWTLASYGLYGLVLYLFSAVDFDQTPKLNWLVLLPSILAICAALAHLRIRSAHGRIAALLMGTYTGLFFWLIPSYVSMVSVWISVVMGVFLLLVYGITLTVILLSPGLVVLARQARKGLRDNPKQDHRPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WSP8</accession>
    <name>A0A0P6WSP8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_16170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72023">
        <property type="protein sequence ID" value="KPL72023"/>
        <property type="gene ID" value="ADN00_16170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="385"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="412" mass="45944" checksum="57AC2B3FFDD49A9F" modified="2016-01-20" version="1">MNDASQFTIDIPQFRALGSLVLASRAPLANLAPLLMATETNISMESLRSAKLVDSEGQIAPYLHSCLRTITNANRVSQIFFLQSDDQILSNLVYYTPDPKSQGLQIDEQGQIQFLEESSLKNVVIQSFFNHQVPIESRIEYTITLTSSDALVLSTLIDMQRMEYLQTAANETTVFKQMLSAQKVADFLDHLGLGFNESDEQETYFDSNALSPNRGFAFLISMLTPPTSLTLQEINTSFVRLAKAGWLVPFQMGYTPGNAILSISRDFLEMERVAFLETHTIKNECIASEEMLCIGMAGKYFTFLVDSENENRVSIVSYTSLSGADLLSKFFRPAQNTSNRIDSGVNQEMQANTISGTQPPPLTNIQTDQEQEPVFPSARKRPRSFWIAVGFAMISILVMCFGCGLAAWAFTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WT14</accession>
    <name>A0A0P6WT14_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DRTGG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_15500</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063939.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15500"/>
    <dbReference type="EnsemblBacteria" id="KPL72224">
        <property type="protein sequence ID" value="KPL72224"/>
        <property type="gene ID" value="ADN00_15500"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1390.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010766">
        <property type="entry name" value="DRTGG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028979">
        <property type="entry name" value="Ser_kin/Pase_Hpr-like_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07085">
        <property type="entry name" value="DRTGG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75138">
        <property type="entry name" value="SSF75138"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DRTGG" evidence="1">
        <location>
            <begin position="5"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="126" mass="13564" checksum="7EECA99DBCB5ADEB" modified="2016-01-20" version="1">MNVQELIELIEGRLLTTNQNHLDMEIKGGFGADLMSDVLTSIEPEAVLLTGLCNPQVVRTATLADVSAIVLVRGKMVPSETIELANQEGIPLISSEKGMFELCAILYNAGLPSFEKPLPNADCGCY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WT52</accession>
    <name>A0A0P6WT52_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HPr domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_15860</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064008.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15860"/>
    <dbReference type="EnsemblBacteria" id="KPL72288">
        <property type="protein sequence ID" value="KPL72288"/>
        <property type="gene ID" value="ADN00_15860"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00367">
        <property type="entry name" value="PTS-HPr_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000032">
        <property type="entry name" value="HPr-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035895">
        <property type="entry name" value="HPr-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001020">
        <property type="entry name" value="PTS_HPr_His_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002114">
        <property type="entry name" value="PTS_HPr_Ser_P_site"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00381">
        <property type="entry name" value="PTS-HPr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00107">
        <property type="entry name" value="PHOSPHOCPHPR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55594">
        <property type="entry name" value="SSF55594"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01003">
        <property type="entry name" value="PTS_HPr_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51350">
        <property type="entry name" value="PTS_HPR_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00369">
        <property type="entry name" value="PTS_HPR_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00589">
        <property type="entry name" value="PTS_HPR_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0598">Phosphotransferase system</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HPr" evidence="4">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51350"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL72288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="89" mass="9578" checksum="46407F5318845D7B" modified="2016-01-20" version="1">MKEIQVMVNTKVGLHARPAALFVQTAKQFSSRITIINAGKDANAKSILNVLALGVYHGTTVQIQAEGEDEDKAIAALLELIESNFGEPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WVM8</accession>
    <name>A0A0P6WVM8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_18060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL69977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL69977">
        <property type="protein sequence ID" value="KPL69977"/>
        <property type="gene ID" value="ADN00_18060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL69977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="169" mass="19116" checksum="988D487A1630F37A" modified="2016-01-20" version="1">MPIFPNEFEQTLLSRDISLNPSQKRYLRTTLLSFEKSLRLISRLLVEDESGILYSRTSAFSPAEIQTLNEKIAAAFEVLQKFTSVLEIESRTEDPLKTIQAQLSLSWVGLEDCHAKQVRSYGKLNDATADTIDQGIEQLIQTLLELMQITSGSQLDDPSIPAYFENDDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WVP2</accession>
    <name>A0A0P6WVP2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_18175</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL69996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064468.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18175"/>
    <dbReference type="EnsemblBacteria" id="KPL69996">
        <property type="protein sequence ID" value="KPL69996"/>
        <property type="gene ID" value="ADN00_18175"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003718">
        <property type="entry name" value="OsmC/Ohr_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036102">
        <property type="entry name" value="OsmC/Ohrsf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02566">
        <property type="entry name" value="OsmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82784">
        <property type="entry name" value="SSF82784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL69996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="150" mass="16794" checksum="FFD77D4D7987CFD1" modified="2016-01-20" version="1">MSRTAVYNTTVQWKNEHWGHIQLGNGPEMDFSAPPDAQGHPGVLTPEDAFVAAGNTCIMMMFIWATERFKLNLVSYECRAEGTKLIELDRTEIFTHLRLWPVIRISAGAEDPAVVEARTQRALQAARKYSLVANSVKSEVIIEPTIEILP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WXW6</accession>
    <name>A0A0P6WXW6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Heat-inducible transcription repressor HrcA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hrcA</name>
        <name evidence="7" type="ORF">ADN00_17615</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Negative regulator of class I heat shock genes (grpE-dnaK-dnaJ and groELS operons). Prevents heat-shock induction of these operons.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the HrcA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000042">
        <property type="protein sequence ID" value="KPL71217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064366.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000042.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17615"/>
    <dbReference type="EnsemblBacteria" id="KPL71217">
        <property type="protein sequence ID" value="KPL71217"/>
        <property type="gene ID" value="ADN00_17615"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2787"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00081">
        <property type="entry name" value="HrcA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002571">
        <property type="entry name" value="HrcA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021153">
        <property type="entry name" value="HrcA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023120">
        <property type="entry name" value="WHTH_transcript_rep_HrcA_IDD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34824">
        <property type="entry name" value="PTHR34824"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01628">
        <property type="entry name" value="HrcA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005485">
        <property type="entry name" value="HrcA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00331">
        <property type="entry name" value="hrcA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0678">Repressor</keyword>
    <keyword evidence="3 5" id="KW-0346">Stress response</keyword>
    <keyword evidence="4 5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HrcA" evidence="6">
        <location>
            <begin position="106"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL71217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="344" mass="38260" checksum="07BF58B0178607EF" modified="2016-01-20" version="1">MIELTDRQKVILSLVIREYTHTAVPVGSKNLVEHYRLEYSPATVRNELAALTEMGYLRQPHTSAGRVPTEDGYRYFVGRLLQRTELPDETRRTIIHQFYQTHRDIDQWMRLAASVLAHQSQGASLVTAPHLMESRFKHLELISTRGRQVLVVLVTVGGQIHQRIMTLNEPVSQEQLSAIGNRLTGLLNGKDARAVSLLRSQLLDLDFEVAGWVEDQMRAADALVSGEIYLDGITNVLAEPEFAESEEARRALRVLEERSVLQDLLSRTVLSEHASGVQVLIGGEGNWEELSQCSIVLAQYGAPGVAVGTLGVLGPMRMSYGRTISTVRFISALLSDFVAETMGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WY15</accession>
    <name>A0A0P6WY15_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 12">Flagellar biosynthetic protein FlhB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">flhB</name>
        <name evidence="13" type="ORF">ADN00_17175</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Required for formation of the rod structure in the basal body of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="12">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the type III secretion exporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064280.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17175"/>
    <dbReference type="EnsemblBacteria" id="KPL71422">
        <property type="protein sequence ID" value="KPL71422"/>
        <property type="gene ID" value="ADN00_17175"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.497"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1690.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006136">
        <property type="entry name" value="FlhB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006135">
        <property type="entry name" value="T3SS_substrate_exporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029025">
        <property type="entry name" value="T3SS_substrate_exporter_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30531">
        <property type="entry name" value="PTHR30531"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01312">
        <property type="entry name" value="Bac_export_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00950">
        <property type="entry name" value="TYPE3IMSPROT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160544">
        <property type="entry name" value="SSF160544"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00328">
        <property type="entry name" value="flhB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-1005">Bacterial flagellum biogenesis</keyword>
    <keyword evidence="11 12" id="KW-1006">Bacterial flagellum protein export</keyword>
    <keyword evidence="5 12" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 12" id="KW-0653">Protein transport</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="88"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="133"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="188"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021622"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022795"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU364091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KPL71422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="356" mass="40048" checksum="D1486F5E55B565D1" modified="2016-01-20" version="1">MSERTEAPTPQRLREAKQEGRVARSVELNSAAILLTGAFLLSAFGSGLSNAMQSLMSDAITIMPTAEVSIGWVRDWFVDEALRILPPLVGMLLVLMLVGVSVTLAQTGLMWAQKKIGFDFKRVNPLQGFKRIFSAQGVVEMFKALLKLVLVSWVAYSFLRSRIEDLLVLNQMDLPSALSNYVELSLSLAFRVGTAYIILAVADYAYQRWEFMRSMRMSKQELKEEFKRTEGDPMLRGRIRQQQRRIAQTRMMANVPKANVIITNPTHYAIAIQYDGGRMNAPKVLAKGAFEVAQKIVEIAKANNIPVIQNQPLARAMFREVEIDREIPQEFYVAVAEVLAYVFNLKKRGGQPVGMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZ21</accession>
    <name>A0A0P6WZ21_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FeoC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_15920</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL71989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064030.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL71989">
        <property type="protein sequence ID" value="KPL71989"/>
        <property type="gene ID" value="ADN00_15920"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015102">
        <property type="entry name" value="Tscrpt_reg_HTH_FeoC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09012">
        <property type="entry name" value="FeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FeoC" evidence="1">
        <location>
            <begin position="5"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL71989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="88" mass="9328" checksum="E6A2D625884D9E4F" modified="2016-01-20" version="1">MLSQILKEIQDHNGSISLAQLSRSMEISPSALEGMLETLVSMGKLQNDAASCHPGENPGGCAFCSSKGACPLVMAMPKSYSLVEKTRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZ99</accession>
    <name>A0A0P6WZ99_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Aldehyde:ferredoxin oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_16415</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AOR/FOR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064124.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16415"/>
    <dbReference type="EnsemblBacteria" id="KPL72059">
        <property type="protein sequence ID" value="KPL72059"/>
        <property type="gene ID" value="ADN00_16415"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3725"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016625">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.569.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.599.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.9.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013984">
        <property type="entry name" value="Ald_Fedxn_OxRdtase_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013985">
        <property type="entry name" value="Ald_Fedxn_OxRdtase_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013983">
        <property type="entry name" value="Ald_Fedxn_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036503">
        <property type="entry name" value="Ald_Fedxn_OxRdtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001203">
        <property type="entry name" value="OxRdtase_Ald_Fedxn_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036021">
        <property type="entry name" value="Tungsten_al_ferr_oxy-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01314">
        <property type="entry name" value="AFOR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02730">
        <property type="entry name" value="AFOR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00790">
        <property type="entry name" value="AFOR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48310">
        <property type="entry name" value="SSF48310"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56228">
        <property type="entry name" value="SSF56228"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AFOR_N" evidence="8">
        <location>
            <begin position="4"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL72059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="601" mass="64542" checksum="51030A7667D0D0AF" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZF3</accession>
    <name>A0A0P6WZF3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pilus assembly protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_15270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063902.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72190">
        <property type="protein sequence ID" value="KPL72190"/>
        <property type="gene ID" value="ADN00_15270"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.756"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="48" mass="5091" checksum="4EE9438A4EF89652" modified="2016-01-20" version="1">MLFAPKEKGQGLVEYALILVLVAVVVIVILALLGPAIGRIFSNVVETI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZH4</accession>
    <name>A0A0P6WZH4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NADP oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_15445</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063931.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15445"/>
    <dbReference type="EnsemblBacteria" id="KPL72217">
        <property type="protein sequence ID" value="KPL72217"/>
        <property type="gene ID" value="ADN00_15445"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.791"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006137">
        <property type="entry name" value="NADH_UbQ_OxRdtase-like_20kDa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037024">
        <property type="entry name" value="NiFe_Hase_small_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01058">
        <property type="entry name" value="Oxidored_q6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Oxidored_q6" evidence="2">
        <location>
            <begin position="14"/>
            <end position="164"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01058"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL72217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="180" mass="20020" checksum="950A388C89C7DFEF" modified="2016-01-20" version="1">MTKPKISTDWMAGCSGCHMSLLDIDERIIKIAELADIRATPITDLKEPDEDGVDVGILEGGVNNTSNEEQAHRMRSRCKLLVAFGDCAVFGGVPAMRNYFTLEEALRRAYVETESTDSEGKIPDDPEICVPTRVRALHEVVPVDLFVPGCPPDPDVIYYVLSELAQGRIPEIKDDKLHWH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZK2</accession>
    <name>A0A0P6WZK2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_15670</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72254.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063971.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15670"/>
    <dbReference type="EnsemblBacteria" id="KPL72254">
        <property type="protein sequence ID" value="KPL72254"/>
        <property type="gene ID" value="ADN00_15670"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72254.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="297" mass="32514" checksum="BB235E5DF659CF9B" modified="2016-01-20" version="1">MTETFYFFDNQPIYQADWVKTIGKSLQDGVICGVDDDLFVYADASGMQVKIKPGAAHIKGNYFFSDQETILPVSAAPTTAGQYRYDWVVCEVDWTARSMTLKIVEGTPGSSPSLPTLTRSSTVFQIPLARLTVSYGDTNVPANKVLDYRSWALGVYAIPFVIGSAQSVITTGPVPVAAIVPVRGKIYRVDMVADQTGSITIDVWKKVLSSYPPTVSESICASGNKPSLSSARSGYKYVWNEATYPNMVSLNWPGHVIDKPSETDFWPYAILLNVDSVATIKQVNVTLWIARSISPLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZY7</accession>
    <name>A0A0P6WZY7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">RNA helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">ADN00_14135</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063692.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000033.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14135"/>
    <dbReference type="EnsemblBacteria" id="KPL74135">
        <property type="protein sequence ID" value="KPL74135"/>
        <property type="gene ID" value="ADN00_14135"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1927"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6 11" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Q_MOTIF" evidence="10">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="8">
        <location>
            <begin position="32"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="9">
        <location>
            <begin position="229"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="378"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="5">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="404"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL74135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="419" mass="46112" checksum="01EC40092A0785EC" modified="2016-01-20" version="1">MNFTQFNLDTRLQARIERAGFTTPTPIQEAAIPVVLSGRDLIGTAQTGTGKTAAFVLPILNKLLRGPRNRTRALIITPTRELAEQIHEVVRLLSAGTKVRSASVYGGVSQGPQVRALKDGTEIIIACPGRLLDLMGQHAADLSAVEMVVLDEADRMLDMGFLPPVQQILEHVPAQRQTLLFSATFEPEVEKLAKRVLTDPQRITIGRSQPAYTVAHSIYPVKQHLKTPLLIELLKQTETQSVLVFTRTKHRASRLAEQIERAGYSVTSLHGDRTQGQRQNALRGFKSGKFQVMVATDIAARGLDVESISHVINYDMPGSADDYIHRIGRTGRAQRSGDAYTLVTGEDMDLVRKLEKILGKPLPRQILTDFDYKVPAPAGAPNTKTAPARPTNKPDKSARNYLRKRGITVTQSSRQPTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X128</accession>
    <name>A0A0P6X128_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Fis family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_11840</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063225.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11840"/>
    <dbReference type="EnsemblBacteria" id="KPL76040">
        <property type="protein sequence ID" value="KPL76040"/>
        <property type="gene ID" value="ADN00_11840"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="4"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="129"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="129"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL76040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="229" mass="26020" checksum="B8E629E969E94D5A" modified="2016-01-20" version="1">MMTLILAVDDETLYQHLLTVNLEKEGYEVITAGDGEQAVEIVANRNPDLVVMDVMMPKLDGISACERIRQFSNVPIIILTARGEEQDRVTGLNAGADDYVVKPFSATELIARVRAVLRRAHSTEQITQNRYFVHGNLKIDFARAEVWKDNKPIFLSATEYRLLIQFAQHIGEVLSSEDLLVAIWGPQYREDKEILWVSIARLRQKLEDEPHNPQHIVTRPGLGYIMPAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X2S4</accession>
    <name>A0A0P6X2S4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">CitMHS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">ADN00_10595</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CitM (TC 2.A.11) transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062969.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10595"/>
    <dbReference type="EnsemblBacteria" id="KPL77009">
        <property type="protein sequence ID" value="KPL77009"/>
        <property type="gene ID" value="ADN00_10595"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015105">
        <property type="term" value="F:arsenite transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000802">
        <property type="entry name" value="Arsenical_pump_ArsB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004680">
        <property type="entry name" value="Cit_transptr-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03600">
        <property type="entry name" value="CitMHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00758">
        <property type="entry name" value="ARSENICPUMP"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="59"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="95"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="119"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="175"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="280"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="318"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="409"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="domain" description="CitMHS" evidence="10">
        <location>
            <begin position="16"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF03600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL77009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="430" mass="45783" checksum="B67BE078D89A26FF" modified="2016-01-20" version="1">MTAIVVSSSIFVFALALIFSEKVNRTIVALAGAVLMVTAGMIFGFYHEEQALEMIDFPTLFLLMGMMILVAVLEPTGFFQYLAVVVGKLSRGRPARLLVLLGTVTTVISMFLDNVTTVVLIAPVTILICEILGLESTPFLIALALLSNTGGVGTLVGDPPNILIGSAAGLTFTDFLLHALPIVVVVWGAALWLLLRMFQKDFESAQLCDPKVLDQLNPREALKDAKTAKRALVVIALAVLAFLMEEKIHVSPSYVALSASALGLTWVRPDIRKTLNRVEWDILVFFAALFVMVGGLEAAGVMHLLANLVASARGLPPVLLGVAVLWLAAIIAAVVDNIPITIAMIPVIQQLGAAGIDIAPLWWALALGTGFGGNGTIIGASANVVVASLSERTRNPITPALWSKRGLPVMLLACLVATLMYVLVFYTVGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X3Y4</accession>
    <name>A0A0P6X3Y4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Pyridine nucleotide-disulfide oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_14100</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the sulfur carrier protein TusA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063668.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000033.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14100"/>
    <dbReference type="EnsemblBacteria" id="KPL74128">
        <property type="protein sequence ID" value="KPL74128"/>
        <property type="gene ID" value="ADN00_14100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1920"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032836">
        <property type="entry name" value="DsrE2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027396">
        <property type="entry name" value="DsrEFH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001455">
        <property type="entry name" value="TusA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036868">
        <property type="entry name" value="TusA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13686">
        <property type="entry name" value="DrsE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01206">
        <property type="entry name" value="TusA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64307">
        <property type="entry name" value="SSF64307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75169">
        <property type="entry name" value="SSF75169"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01148">
        <property type="entry name" value="UPF0033"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="3">
        <location>
            <begin position="464"/>
            <end position="551"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL74128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="819" mass="89498" checksum="2EF6E9F06D61D8A8" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X518</accession>
    <name>A0A0P6X518_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Pyridoxal phosphate homeostasis protein</fullName>
            <shortName evidence="1">PLP homeostasis protein</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_10085</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Pyridoxal 5'-phosphate (PLP)-binding protein, which is involved in PLP homeostasis.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pyridoxal phosphate-binding protein YggS/PROSC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76933.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062876.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10085"/>
    <dbReference type="EnsemblBacteria" id="KPL76933">
        <property type="protein sequence ID" value="KPL76933"/>
        <property type="gene ID" value="ADN00_10085"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2480"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02087">
        <property type="entry name" value="PLP_homeostasis"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011078">
        <property type="entry name" value="PyrdxlP_homeostasis"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10146">
        <property type="entry name" value="PTHR10146"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004848">
        <property type="entry name" value="YBL036c_PLPDEIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00044">
        <property type="entry name" value="TIGR00044"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ala_racemase_N" evidence="4">
        <location>
            <begin position="11"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="1 2">
        <location>
            <position position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02087"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR004848-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL76933.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="224" mass="24842" checksum="BA247FA9204F867D" modified="2016-01-20" version="1">MIESSLRIVEAVKAIRKTIPAGVTLLAAAKTRTLPEVEAVIEAGVTHIGYNYIQESLPIIRAIGSRATWHMIGHLQRNKAKVAAEFFDIIETVDSWALAQALERHAASLQKKLPILVEINSGREPNKDGVLPEEVDELIAQLSTLTYLQVQGLMTMGPRFGNPEDSRPFFVATRQVFDRLAKQSLPNVEMRYLSMGMSNSYLIAIQEGANIVRIGTKLFGERSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5D5</accession>
    <name>A0A0P6X5D5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 4">Beta-lactamase</fullName>
            <ecNumber evidence="2 4">3.5.2.6</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_10330</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a beta-lactam + H2O = a substituted beta-amino acid</text>
            <dbReference type="Rhea" id="RHEA:20401"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:35627"/>
            <dbReference type="ChEBI" id="CHEBI:140347"/>
            <dbReference type="EC" id="3.5.2.6"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the class-D beta-lactamase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.6" evidence="2 4"/>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10330"/>
    <dbReference type="EnsemblBacteria" id="KPL77070">
        <property type="protein sequence ID" value="KPL77070"/>
        <property type="gene ID" value="ADN00_10330"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2532"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008800">
        <property type="term" value="F:beta-lactamase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017001">
        <property type="term" value="P:antibiotic catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002137">
        <property type="entry name" value="Beta-lactam_class-D_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00337">
        <property type="entry name" value="BETA_LACTAMASE_D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transpeptidase" evidence="5">
        <location>
            <begin position="50"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="active site" description="Acyl-ester intermediate" evidence="3">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-carboxylysine" evidence="3">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR602137-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL77070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="254" mass="28017" checksum="C52F71B355F8A3A9" modified="2016-01-20" version="1">MPVTAGSPPTPVAYTMPELAIYFEGFEGAFVLYDPAQNRLLRYNPRGGAARYLPASTFKILNSLIGLETGVIADEHDVIAWDGTPQPVDSWNQDHTLESAIQNSVVWYYQALARRVGEERMRQWVEAAGYGNADISGVIDTFWLEGALRISADEQVDFLRRFYDGELPFSARSVEIVKKILVLEEGEGYRLSGKTGSVVRSVEYVGWFVGYLEIDGQVYFFATNIHGSQAAANGVKAQAITRAILQGLGLLPAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5G9</accession>
    <name>A0A0P6X5G9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_19215</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064655.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_19215"/>
    <dbReference type="EnsemblBacteria" id="KPL70159">
        <property type="protein sequence ID" value="KPL70159"/>
        <property type="gene ID" value="ADN00_19215"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00659">
        <property type="entry name" value="UPF0250"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007454">
        <property type="entry name" value="UPF0250"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027471">
        <property type="entry name" value="YbeD-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38036">
        <property type="entry name" value="PTHR38036"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04359">
        <property type="entry name" value="DUF493"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117991">
        <property type="entry name" value="SSF117991"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="91" mass="10451" checksum="CC9555324D69E758" modified="2016-01-20" version="1">MTATGKDEKIMLYPCKFPLKAVGHNEEGFFETVVDVVSRHIPGLEEHHFSSRLSSGDKYMSVSVTFIAESREQVDRLYIEMSENKRILMIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X657</accession>
    <name>A0A0P6X657_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Amino_oxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13465</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063541.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000031.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13465"/>
    <dbReference type="EnsemblBacteria" id="KPL74841">
        <property type="protein sequence ID" value="KPL74841"/>
        <property type="gene ID" value="ADN00_13465"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amino_oxidase" evidence="1">
        <location>
            <begin position="15"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="537" mass="61118" checksum="585DAFC3D8D79140" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7H1</accession>
    <name>A0A0P6X7H1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_12980</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000028">
        <property type="protein sequence ID" value="KPL75299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063449.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000028.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12980"/>
    <dbReference type="EnsemblBacteria" id="KPL75299">
        <property type="protein sequence ID" value="KPL75299"/>
        <property type="gene ID" value="ADN00_12980"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL75299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="397" mass="44857" checksum="560987BF69E18E24" modified="2016-01-20" version="1">MIIIKLETKEPLHLSASYTVSTYSPCIEYIPGSALRGGMAKKFLQEDQNQEDFERFFLDDHVRFGPLWPAQNSPQGAIGAILLPMTAYTCKRYPGVYSSKTGYTKHGIRDMLFEFIKEPTGTSSLNCSEQDCEAPLTRQTGYYIGQEAHMELIELDKRVITSTAIDDQTQTAAPEQLFTLQVIEEGQMFWGQIEFGDPDLEEMFCQLCCETGIQIRLGAGTSRGLGLMEVKDIYPSDNHPNYNLFSVTQSLLERIQEFDSVAKMELGDRFANQTCTCFSLDLLSDCLLLDEFLQYKIRIEPSDLARYIHPDLSRAAPLGQVCTSQFVDGWNNLHCLPRETSVAISAGSVFFYCIDVPPQELANLLGQVEYRGIGERTQDGFGRVTINHPFHLKREQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7H8</accession>
    <name>A0A0P6X7H8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_18930</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064605.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70117">
        <property type="protein sequence ID" value="KPL70117"/>
        <property type="gene ID" value="ADN00_18930"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="130" mass="14654" checksum="DED8E2971B433E63" modified="2016-01-20" version="1">MAEINQIERWIFEILSADSALSQLSKGVYAHPADQNAEYPFVSFQYQGGFDLNGVGARRIYVNALYLIRVIGKNCGIEDLKLVADRIDSLLTTQNEGSIACLREQPFSMVEVEDGIRYPHLGGLYRFYLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X8X5</accession>
    <name>A0A0P6X8X5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_11605</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063182.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11605"/>
    <dbReference type="EnsemblBacteria" id="KPL76003">
        <property type="protein sequence ID" value="KPL76003"/>
        <property type="gene ID" value="ADN00_11605"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132923" evidence="2">
        <location>
            <begin position="28"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="209"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="236"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="268"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="294"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL76003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="338" mass="35472" checksum="0A82A097A04ACBB0" modified="2016-01-20" version="1">MRQFKNCLLILVLFTALFFASPVSVQAAQTSPDGEVVLGGTYTLESGDTLNGGLVVIGGQATLEKGSSVYGDILITGGTLSASGEIFGSVTAIGGSINLEETAVVHGDVNTVGSVLNKADEAVITGSLSFDVPSDMDFNFLPKVPFPSFDEPKKEPFGINLQPVWDFLWAIFQAIALAAFAALLSLFLQKPIEHVAGSFMASPFASWGLGLLTMVVAPGLLILLIVTIILIPLGLIGILALGLCLLFGWVAIGYELGKRMEALFHQTWAPAVSIGLGTLVLSLTASLFNAIPCVGWTIPILVSMFGLGGVFLSRFGTITYTPTAPHTVPAGVQENKPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9E3</accession>
    <name>A0A0P6X9E3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HlyD_D23 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_05525</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78707.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061976.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05525"/>
    <dbReference type="EnsemblBacteria" id="KPL78707">
        <property type="protein sequence ID" value="KPL78707"/>
        <property type="gene ID" value="ADN00_05525"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132931" description="HlyD_D23 domain-containing protein" evidence="2">
        <location>
            <begin position="28"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="3">
        <location>
            <begin position="230"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="120"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="221"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL78707.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="394" mass="42128" checksum="86D343B2C7CE3D1B" modified="2016-01-20" version="1">MKKQTYLLLALAFIMFFTAGCSQKTQATPTVDPALLEDFSPVVTATGVVVPAQWATLSLSSAGVVDEFMVAEGDTVEQGQVLLVLGGNEAAQAAVAGAQLELLSATKAHDDLVANHEVIRAQAELELAQAKIALNDAEKERERKNFRRAGNATIDGLRADFVLAKEALDNAEEAFEGVADRDEDDAIRAQALSALSNARKAYDRALQNLNYALGLPDAEEVQEAEAKLALAQARLEKAQVDYDKVKDGPDPEQLAIAEARVENAQKQLASAQKTLQDQTLTAPFAGVVSRLYLREQEWGMAGQPVLQIADLANLRVETTDLSEIDVASVSVGDTAAITFDALPDVVVEGVVQQIAPRADEGSGVNYKVVLELNTIPAGLRWGMTAFVDIEIGDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XA46</accession>
    <name>A0A0P6XA46_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">TetR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_10570</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063044.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77078">
        <property type="protein sequence ID" value="KPL77078"/>
        <property type="gene ID" value="ADN00_10570"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2585"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="3"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="190" mass="21322" checksum="AEBD2CA16F3B7DB2" modified="2016-01-20" version="1">MSSENRDRILDCALRLFAARGYAAVGVQEIVDEAAITKPTLYHYFGSKLGLLEALLQTHLAQRDALLNPVLAYRGDLIHSLNQITLALFRFARANPTFYRLYLALWFAPPASEAFQTASPYHLRLHSDFETLFAQAANDHGNMRGRQQAYAASFLGLVHTYIGLALNDYGELDDALAYQVVHQFMHGIFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAK5</accession>
    <name>A0A0P6XAK5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_15320</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72198">
        <property type="protein sequence ID" value="KPL72198"/>
        <property type="gene ID" value="ADN00_15320"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="406" mass="44811" checksum="9ECC39721B70EB53" modified="2016-01-20" version="1">MGVVVKEIIVLFDMDNVLLTPGGYRMAFRDALRYRLSKGGVADRIPLESLPEIFESVGVTNEWDMMAVTLAVLVDDLLAHKDEFPSLISLEDCVEWLASLPADRFAVDYRSKIRGVVKHAAPGKPVSLSIYHACREDSTNSLLPNLKQQEYFASSLLAHTPDVYQSSLTRMFQNLILGSKQFEAAYHLPAEVQCDSYLDMYDHSNLSPENRDWVLSQASSGLIHPVLFTARPSYPPRGVELPERTLYSPEAEAGARLVGLGSLPLIGMGSMEYMAGKAGKSLNELLKPNVFHAVAAVLASVYNDDLKSLYAAYHWCFAGQVGKMDKEWDLPLEVHVFEDSPGGVRAAIGAVDLFRQRGLDCQLVIWGVADHPDKQSSLEKLGGRVFPCFDAALGAFRQMVNNNGND</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBI6</accession>
    <name>A0A0P6XBI6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">LuxR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_16440</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064129.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72064">
        <property type="protein sequence ID" value="KPL72064"/>
        <property type="gene ID" value="ADN00_16440"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="4"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="146"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL72064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="216" mass="23851" checksum="75F180C8592100F9" modified="2016-01-20" version="1">MPIKVLLVDDHKIVRQGVRAYLCTLADIEVIAEADSGAAALLAVDQHHPDVVLMDLEMPGELDGISTTRQIRKQHPATQVIVVTSHHQDEYIFPAVRAGAVSYLLKDVEPDELADAIRKAASGEAVLDSRVASRIILELQGLRQDEVNPFTELSEREFEVLRLIAAGKSNAEIANTLVIGESTVKTHISNLLKKLHLEDRTQAAVYAWQQGIVRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBW1</accession>
    <name>A0A0P6XBW1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09045</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062673.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09045"/>
    <dbReference type="EnsemblBacteria" id="KPL77273">
        <property type="protein sequence ID" value="KPL77273"/>
        <property type="gene ID" value="ADN00_09045"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12680">
        <property type="entry name" value="SnoaL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="11"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="134" mass="14999" checksum="80DC77AFA78F97A8" modified="2016-01-20" version="1">MNIQEENINIVKSLYEAFGKRDINRILAMLHPDVEWGEPSNPFNPAGGTHHGHAGFLEWANIGRQSEEILVLQPIKMLTDHDSVAVVGTMKCLALPTGKTYESDFVHLVTIEAGKVTKFQEFFDTYLAGEAFRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XC18</accession>
    <name>A0A0P6XC18_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Response regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_09465</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062745.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09465"/>
    <dbReference type="EnsemblBacteria" id="KPL77337">
        <property type="protein sequence ID" value="KPL77337"/>
        <property type="gene ID" value="ADN00_09465"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="288"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="407" mass="47211" checksum="EBE0B04A724F6468" modified="2016-01-20" version="1">MDRHEFQNNVKDILNHLSDPAYLENRNLINLFYNGEDAPLTVRMQTLRDTFQECVNFLQPPEGTPTNAAEWRCQRILTLRYFQLKEWHFIEEELGLSQRQVQRDLKKGLDALISILWDRFMTQNQDLTQPDGKSEEELENYEQELIKEELKNWEISLDLINLSQILEQALQLCKSQLGAEFHHSVDMRDVDVNLNVVVDQVLTKQGLYKIFSIMSDCMDSLESQIKTRKLNDFFHELEFTFNSTNMCSLNQWSIAQLFFSIQGLRNNIVESNGLTVVSIIFPVKKHSSCLVIDDVESVRRLIERMLGSFGIQVFGADNYNHALNLIQLVKPDFILLDILMPKMDGWQMIKNLKSNPDTSKIPVIICSVLFEPELSQAVNAAGYIRKPINRLELINTLQELNLIKTVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDI7</accession>
    <name>A0A0P6XDI7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">TRAM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_07910</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily. RNA M5U methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062448.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07910"/>
    <dbReference type="EnsemblBacteria" id="KPL77804">
        <property type="protein sequence ID" value="KPL77804"/>
        <property type="gene ID" value="ADN00_07910"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.582"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034470">
        <property type="term" value="P:ncRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030390">
        <property type="entry name" value="MeTrfase_TrmA_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030391">
        <property type="entry name" value="MeTrfase_TrmA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010280">
        <property type="entry name" value="U5_MeTrfase_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11061">
        <property type="entry name" value="PTHR11061"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01938">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05958">
        <property type="entry name" value="tRNA_U5-meth_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51687">
        <property type="entry name" value="SAM_MT_RNA_M5U"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01230">
        <property type="entry name" value="TRMA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01231">
        <property type="entry name" value="TRMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TRAM" evidence="6">
        <location>
            <begin position="6"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="active site" evidence="5">
        <location>
            <position position="374"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="374"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="283"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="304"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="347"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL77804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="418" mass="46312" checksum="273E481B6FE7447E" modified="2016-01-20" version="1">MKDEKMAKASDWVEVTVEKAVYGGDGMGRLADGRAIFVPFGLPGEIVWVEIVEEKRGHARGIIREWVSCSPERIEARCRHYGLCGGCHYQHLPYEKQLEFKREVVQEQLERIAGVKDVRVDATVASPKTWNYRNTIQFHLSETGKLGFLEAGSHRVVEISECHLPETVIDEVWKKLEFDSGAGYERIEVSQGADEEALITLYSSSLEMPEMELDLPVSAVQINPAGKVVLAGDDCLWMEVLGRTFKVSAGSFFQVNLGVAEKMVEHVISLIPADRQQSLLDLYCGVGLFSAFAASKVGQVTGVELSESACDDFADNLQEFDNVSLYVGAAEDVLPALTQKYDIVIADPPRAGLQREALDALVKVAPKKIIYVSCDPSTLARDAKRLIEKGYTLAQATPFDMFPQTYHVETVAVFDRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDN7</accession>
    <name>A0A0P6XDN7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">rRNA methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_08170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08170"/>
    <dbReference type="EnsemblBacteria" id="KPL77849">
        <property type="protein sequence ID" value="KPL77849"/>
        <property type="gene ID" value="ADN00_08170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="L30e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013123">
        <property type="entry name" value="SpoU_subst-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08032">
        <property type="entry name" value="SpoU_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00967">
        <property type="entry name" value="SpoU_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="SSF55315"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SpoU_sub_bind" evidence="1">
        <location>
            <begin position="32"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="269" mass="29676" checksum="370C80992EFFF481" modified="2016-01-20" version="1">MTEIITSLSNPRIKQIRKLRERKERASSGLFFIEGLRIVGDAFDHGSPIESLVCAPELLESEFGLSLVEKARSQGIAVLEVSADVFQSLSTKEGPQGLAAVARQVWSSIDEIQMDSKDLWVALDSVADPGNLGTILRTLDAVDGKGVILLDHCTDPFDPSCMRASMGSIFTMRVVKCTFEEFAGWKQRQPFFLVGTSDRAETDYEATTYPLPLVLLMGSERMGLQSHHVSLCDQMVSLPMRGAMDSLNLAVATGVMLYQIHSYQRKLQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDZ4</accession>
    <name>A0A0P6XDZ4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_14915</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000036">
        <property type="protein sequence ID" value="KPL73079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063830.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000036.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14915"/>
    <dbReference type="EnsemblBacteria" id="KPL73079">
        <property type="protein sequence ID" value="KPL73079"/>
        <property type="gene ID" value="ADN00_14915"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="domain" description="Nudix hydrolase" evidence="2">
        <location>
            <begin position="7"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL73079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="147" mass="16231" checksum="3C2524F8F3A65380" modified="2016-01-20" version="1">MKRGIDYIGVGVGALIVNAQGLVFLARRGPLAKNERGLWEFPGGSVEFGETLAQSLIREMREEFGITISVGRLLDVVDHILPEEKQHWVSPTFICSITSGEPAIQEPGKCAEIGWFDPHVAPPDLTQITRENLRHYLALIQPQSASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XEH7</accession>
    <name>A0A0P6XEH7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_14545</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000035">
        <property type="protein sequence ID" value="KPL73560.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063758.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000035.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14545"/>
    <dbReference type="EnsemblBacteria" id="KPL73560">
        <property type="protein sequence ID" value="KPL73560"/>
        <property type="gene ID" value="ADN00_14545"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021441">
        <property type="entry name" value="DUF3090"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11290">
        <property type="entry name" value="DUF3090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03847">
        <property type="entry name" value="TIGR03847"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL73560.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="175" mass="19840" checksum="CD746DDAEEF7E2DD" modified="2016-01-20" version="1">MPQNIIDFSPIDHITTDAIGKPGQRVFYIQARSGSRVITILVEKIQIQTLAIGVEQFYAELRERYPDLDEPMPDYDEEKMAIHPPVDPLFRAAELGLAYDSDKDLMALMAVEALGDGQPEEEGRMIRLWCTRAQLRALCRWGLEVAGRGREICPYCGEPMDPEGHFCVKKNGHKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XEX3</accession>
    <name>A0A0P6XEX3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_05690</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062003.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05690"/>
    <dbReference type="EnsemblBacteria" id="KPL78733">
        <property type="protein sequence ID" value="KPL78733"/>
        <property type="gene ID" value="ADN00_05690"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="263" mass="29755" checksum="F8459380C5CCBE0E" modified="2016-01-20" version="1">MYKAIICFDLDGTLLDERERIRKPDMEILQNNRDYLFVPATGRSYESVKRLFHQNQLFVGQKLPLPLITMNGAVAFAPQEEMVVEFLFTAAEKQQIRSVIEKNQHISFLMQGHDNSYLLWPNEFGLGCLNRYDLHYTLDPMPESFEFFKVMCFCGEPDVLHSFVNSVKELPVEKAYGTPFIYEFTPPGVNKGRALTALAESMNVSHLPIFAAGDGGNDVETFRVAKRSFAPKGSLPFVLDAADEVIEPDGVGLLSQMIERSMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XF08</accession>
    <name>A0A0P6XF08_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cupredoxin_1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_07015</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78224">
        <property type="protein sequence ID" value="KPL78224"/>
        <property type="gene ID" value="ADN00_07015"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028096">
        <property type="entry name" value="EfeO_Cupredoxin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13473">
        <property type="entry name" value="Cupredoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="SSF49503"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133019" description="Cupredoxin_1 domain-containing protein" evidence="1">
        <location>
            <begin position="38"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="Cupredoxin_1" evidence="2">
        <location>
            <begin position="27"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="155" mass="17537" checksum="A0F7A612FF6CAD99" modified="2016-01-20" version="1">MDDLAYRLRPDYNTSMPNKKRLGLFCLLLLLLASACARDPYEQVSTRQRVSIQDASFSPRQWKVPAGKEISFEAQNFSSRDLEFSILTANIEPPLRPQDTEIIWFSTSLPSDQKVQFSFQSPSMPGEYDVLLDSTAASGQEWLGKLVVYSPEVLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XFH7</accession>
    <name>A0A0P6XFH7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Histidine kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_03375</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03375"/>
    <dbReference type="EnsemblBacteria" id="KPL78952">
        <property type="protein sequence ID" value="KPL78952"/>
        <property type="gene ID" value="ADN00_03375"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.25"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13492">
        <property type="entry name" value="GAF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="146"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="171"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="207"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="237"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="272"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="336"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="368"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="1083"/>
            <end position="1311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL78952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="1313" mass="143890" checksum="ECEC4FAADF702478" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XFX6</accession>
    <name>A0A0P6XFX6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_04260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04260"/>
    <dbReference type="EnsemblBacteria" id="KPL79089">
        <property type="protein sequence ID" value="KPL79089"/>
        <property type="gene ID" value="ADN00_04260"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.209"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="189"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="217"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="248"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="312"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="353"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="456"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="502"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="532"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="560"/>
            <end position="579"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="609" mass="67334" checksum="9BE6FBF03702D72F" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XG20</accession>
    <name>A0A0P6XG20_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_04565</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061774.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79135">
        <property type="protein sequence ID" value="KPL79135"/>
        <property type="gene ID" value="ADN00_04565"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="226"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="261" mass="29293" checksum="905D3C1308B5687C" modified="2016-01-20" version="1">MVSPTQNKKWAVLSALILFGVNGLVLILMEIPHEWSLPAWFRALAGAFMIVELLVAPLGLFLGWLAGFPRWVFPYATQALLMSFYMHNVATPGLKIFSYTFGPRDLWSWRAWLPLGLACAAALLITRSLEPLKQAFRQVEADSSVLAYAYLGCLPLFIAVNFDEMDRLYSFYFMLAFTVILLVTSVLYVWIEDRKAHSRVLAAGGTLILLAIPIGVHLYWTRTFGVNEAVSVACFSTLLLLYLLCFTPIFFPPPTRKTQAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XG57</accession>
    <name>A0A0P6XG57_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_18480</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MgtC/SapB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18480"/>
    <dbReference type="EnsemblBacteria" id="KPL70045">
        <property type="protein sequence ID" value="KPL70045"/>
        <property type="gene ID" value="ADN00_18480"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3004"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003416">
        <property type="entry name" value="MgtC/SapB/SrpB/YhiD_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33778">
        <property type="entry name" value="PTHR33778"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02308">
        <property type="entry name" value="MgtC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01837">
        <property type="entry name" value="MGTCSAPBPROT"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="64"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="114"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL70045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="215" mass="23884" checksum="3A0BC584CE32E53E" modified="2016-01-20" version="1">MASWLAFSMQDLTKIGLALLIGGLIGSERELRDKAAGLRTMMLVCVGSTIFTLFSFRFAPNGDVTRISAAVVTGIGFLGAGVIMREGGQIKGLTTASTVWLVSALGMGIGGGEYGFVIAVTLIILFVLWAFPRLEAAMGKLNETRTYEVLSDRDVEFFHDLENMWKEHRLRIHFRRQAKSPKGRLTVWVVSGPPSQHDHATEWLFSNKKVIRFRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGW8</accession>
    <name>A0A0P6XGW8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_03190</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000014">
        <property type="protein sequence ID" value="KPL79345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061515.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000014.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03190"/>
    <dbReference type="EnsemblBacteria" id="KPL79345">
        <property type="protein sequence ID" value="KPL79345"/>
        <property type="gene ID" value="ADN00_03190"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2050"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025302">
        <property type="entry name" value="DUF4162"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13732">
        <property type="entry name" value="DUF4162"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="12"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="44"/>
            <end position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL79345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="316" mass="35171" checksum="58E995AA6155CB4A" modified="2016-01-20" version="1">MIKQTSNGKAAIRCENLTRYYGDVAALKQLNLTVPEGSIFGFLGRNGAGKTTTIRLLTGLAHPTQGSAWVAGVETTNGDDSAREQFGYLPQEPAFYTWMTASEFLNYCAQIYNIPEKQRKARVAEILEQVGLKEAAKRKIAGFSGGMRQRLGIAQAMIHNPPVLFLDEPTSALDPAGRYEVLDMIERLRGQVTVFLSTHILSDVERICDQVAVIHKGELLLVSDREALLEHYASNAAEIELDSSSLDQLAAVKQQLEQQEWVSRILEDQNVLRVMVDDLATARQNLLPLVAACHLVVNRFEWVRSSLEEIFLKVSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XH16</accession>
    <name>A0A0P6XH16_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_02890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000013">
        <property type="protein sequence ID" value="KPL79391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061454.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000013.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02890"/>
    <dbReference type="EnsemblBacteria" id="KPL79391">
        <property type="protein sequence ID" value="KPL79391"/>
        <property type="gene ID" value="ADN00_02890"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="56"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="281" mass="30810" checksum="6759B691828D16FB" modified="2016-01-20" version="1">MKNEIVFKSAAGRQAILGVYDSVLEGWPVPFQMRRVETRHGQTFLIECGQASAPALVLLHGAGSNAAFWRGEVETLGRTWRVLIPDIPGEAGKSEERRASLSSPAYVEWLEDLFAAEGLDQVAVAGLSLGAWMGMKFAAAHPQQVSRLALLSASGIAPQKNSFLLLAVALMLCGDWGLERMARMVGGGQPMPREVMDYTKLIHREFNARLEVVPLLSDEELARLSMPVLLWMGEKDVMLDSRKSAARLRALLPHAEVEVSQGVGHVLPRMGTRIGAFLEER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XHI0</accession>
    <name>A0A0P6XHI0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cupin_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13835</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063613.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000032.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13835"/>
    <dbReference type="EnsemblBacteria" id="KPL74368">
        <property type="protein sequence ID" value="KPL74368"/>
        <property type="gene ID" value="ADN00_13835"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="1">
        <location>
            <begin position="46"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="122" mass="13442" checksum="2EDA5388377F0477" modified="2016-01-20" version="1">MTEAKGKVIHYSKVEGQSMGDVAPGATIRWLIDDDHDGAPTYALRMIELAPGGHSPHHSHPYEHENFVVEGEGQVLMDGVWHDLKAGDVVFMPPNADHQYRNAGSTVFKFLCGIPVKKLLPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XHW9</accession>
    <name>A0A0P6XHW9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_02640</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000012">
        <property type="protein sequence ID" value="KPL79431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061410.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000012.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79431">
        <property type="protein sequence ID" value="KPL79431"/>
        <property type="gene ID" value="ADN00_02640"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="155" mass="17123" checksum="E3899BA283D1B706" modified="2016-01-20" version="1">MFLLKGFHLVFKIFKNALLLLVIATILFIAYRGNLPMSVPQAPQGITYFEFMADRIDAAKTVKPSQCGWGMMLSLAALGPIYSVVYTTVAVNPDSALAKGTAPDPDIARDVAGAAWYQIPDIWWKTVERLSWTMLGKPAAYGCQFRPVQIAEHTN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKJ0</accession>
    <name>A0A0P6XKJ0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_16205</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064085.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16205"/>
    <dbReference type="EnsemblBacteria" id="KPL72029">
        <property type="protein sequence ID" value="KPL72029"/>
        <property type="gene ID" value="ADN00_16205"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017111">
        <property type="term" value="F:nucleoside-triphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004948">
        <property type="entry name" value="Nuc-triphosphatase_THEP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03266">
        <property type="entry name" value="NTPase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL72029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="185" mass="20520" checksum="20F420EBD96B79CE" modified="2016-01-20" version="1">MNEAGTVLIITGWRGAGKTSLCQMVVEQARQRGWDVAGVISLPVLEKSVKTGIEIIAIRSNERRLLARSTALANTTLQTHAWAFDPVNMQWGNEILKSAVPCDLLMVDELGPLEFERQQGWLEGLRALDSGQFKLALVVIRPELVAQARSRWPQAVELQINTVTEAPALAQQIIDQWLRSPANRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKK2</accession>
    <name>A0A0P6XKK2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061178.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80534">
        <property type="protein sequence ID" value="KPL80534"/>
        <property type="gene ID" value="ADN00_01420"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="214"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="246"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="310"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="342"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="375"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="406"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="459"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="490" mass="55755" checksum="7487CC52C832E59E" modified="2016-01-20" version="1">MNEKISQLLRLLDDLLAALFYRETEKKHAWLGGVWLAGLYALGVYAWGRFLNWGKIPFDWLDWAEINAPRTAFLKDAMMLGVLPLHMPDASALREVTDRFMCLPDVLLSPDILLLRFMEVGPFFLVHTLILYTLGALGLLALRKKFNLSLAAFTGLFLLFNFNGHILAHYSVGHITWGGYLLFPWLFLLAFQFLEGDYSWKWVAKTAGLLLLMYLQGSFHQFVWSLMLLGLLGLTARECFIPALKALVFSCLLSLVRILPPVLLLGKFDQDYLGGYPTAWDMLMSMVSFKFPAESFTVQSMLSDLAWWEYNLYIGLAGALWVGVFGLYLWARRRDSQHGYPAFWLPIVVLTLFSLGRIYRVVRYIPIPLLSGERASIRMLIVPAALLMVLAALEMQHWLNQRRPGWLERLGLLGGLLMIAHDLWQHLKVWQVDNAYLPFDVTPVDLDIKIVANRPDPPYITMVAVGAALSLLTLIFLLVMARREARGGKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKR1</accession>
    <name>A0A0P6XKR1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PBPb domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_01105</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000003">
        <property type="protein sequence ID" value="KPL80821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061121.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01105"/>
    <dbReference type="EnsemblBacteria" id="KPL80821">
        <property type="protein sequence ID" value="KPL80821"/>
        <property type="gene ID" value="ADN00_01105"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1965"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133109" description="PBPb domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="PBPb" evidence="3">
        <location>
            <begin position="38"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL80821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="264" mass="28505" checksum="DAECA640B91C8F09" modified="2016-01-20" version="1">MKSKFYVVFALVMVAVLLAACGGGAAANKLEAIKKNGKVVIGTSADYPPFEFVDANGNFDGFDVALMNKLGEEMGVTVEIQDMPFDSLIAAVQEGKIDLAIAAFNYNEERDKTVDFSDPYYYAEDGFVAAEGFAGEFTKPEDAANYKLGVQTGSTADGWVTENLLDTGLIAEANLFRYERIDQAGLDVKSGRIDLLMTDYVPALALAQNLGGLKVIYHAELSTGPVNIILPEGEKELQAELNTIIKKLQDSGFIDEIAAKYIGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKS9</accession>
    <name>A0A0P6XKS9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">Cysteine desulfurase</fullName>
            <ecNumber evidence="4 6">2.8.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_15360</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the removal of elemental sulfur and selenium atoms from L-cysteine, L-cystine, L-selenocysteine, and L-selenocystine to produce L-alanine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>[sulfur carrier]-H + L-cysteine = [sulfur carrier]-SH + L-alanine</text>
            <dbReference type="Rhea" id="RHEA:43892"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="EC" id="2.8.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 5">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. Csd subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.7" evidence="4 6"/>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72203.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15360"/>
    <dbReference type="EnsemblBacteria" id="KPL72203">
        <property type="protein sequence ID" value="KPL72203"/>
        <property type="gene ID" value="ADN00_15360"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.774"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031071">
        <property type="term" value="F:cysteine desulfurase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006534">
        <property type="term" value="P:cysteine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06453">
        <property type="entry name" value="SufS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010970">
        <property type="entry name" value="Cys_dSase_SufS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01979">
        <property type="entry name" value="sufS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="7">
        <location>
            <begin position="32"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL72203.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="413" mass="45032" checksum="3F80C7518A148B45" modified="2016-01-20" version="1">MSSNRSRLDPEQIREDFPIFRRILPNGKPLTYLDSAATSQKPNAVIDAMDTYYRGLNANIHRGVHTLAEEATEAYEGARARIGRFIGAKKAREIIFTRNTTESINLVAQSWGRRNLSAGDVVILTEMEHHSNLVPWQILAAEKELRLEFVPITEDGRFNMEQYQALLGLNPKLVGFSHMSNVLGSIQPAREIIALAHQAGAIVLVDGAQSVPHLPVDVAELDTDFLAFSGHKMCGPTGIGVLYGKEALLESMPPFLGGGDMIKKVTLQGFTANSLPHKFEAGTPAIAEVIGLGAAVDYLSGLGMEAVAAYEQELARYGIEQLEKVDGLRLLGPNADHKGSVFAFTLGDIHPHDVAQLLDQSGIAVRAGHHCAMPLHQKLNIPASTRASLYIYNSKNEIDRLVESLQSVKKVFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XL08</accession>
    <name>A0A0P6XL08_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Isochorismatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09665</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062796.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09665"/>
    <dbReference type="EnsemblBacteria" id="KPL76861">
        <property type="protein sequence ID" value="KPL76861"/>
        <property type="gene ID" value="ADN00_09665"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2390"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="SSF52499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase" evidence="1">
        <location>
            <begin position="11"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="184" mass="19738" checksum="3E98063B06289F4D" modified="2016-01-20" version="1">MATIRAGSQAVLLVVDVQLGVMRGAWNAAQVIQNIGVAVEKARAQGAPVIWVQHADDELVSGSADWQIVPELPPAPGETRIHKQFNSAFEQTALEETLAQLNAARIVLAGAATNWCIRATAYAALERGYDLTLLQDAHTTETLELGGGIKIEAQDIVRELNIAMTWLSFPGRKNSVAPAAEVVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XL16</accession>
    <name>A0A0P6XL16_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA-directed RNA polymerase subunit delta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09765</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SAM hydrolase / SAM-dependent halogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76879.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062814.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09765"/>
    <dbReference type="EnsemblBacteria" id="KPL76879">
        <property type="protein sequence ID" value="KPL76879"/>
        <property type="gene ID" value="ADN00_09765"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2410"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002747">
        <property type="entry name" value="SAM_Chlor/Fluor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023227">
        <property type="entry name" value="SAM_OH_AdoTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023228">
        <property type="entry name" value="SAM_OH_AdoTrfase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35092">
        <property type="entry name" value="PTHR35092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01887">
        <property type="entry name" value="SAM_adeno_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006779">
        <property type="entry name" value="UCP006779"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101852">
        <property type="entry name" value="SSF101852"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102522">
        <property type="entry name" value="SSF102522"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00024035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76879.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="282" mass="31339" checksum="18F3D5341D38AA07" modified="2016-01-20" version="1">MKPILVFQTDFTYKEGAVCAMYGVVKSVDRELEIIDGTHEIPQYDIWSASYRLVQSMHFWPEGTIFVSVVDPGVGTPRKACVAKTAHGYFVVTPDNGSLTHLKAWVGISEVREIDQSVNRLRGKGTEGTSVFHGRDLFGYCAARLASGIITYEGVGPAYPVDEIVTLPIVEPSLQDGKVRGIFEIGDPNFGNLWTNIPLNLFTQAGFAYGDTLRLTVRREGNVEYQANVPFQPSFGYAPKGEVVIYNNELMRVSVAVNQGSFSERTHLSYGPEWQVEFEKVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XL26</accession>
    <name>A0A0P6XL26_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_09870</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062833.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76897">
        <property type="protein sequence ID" value="KPL76897"/>
        <property type="gene ID" value="ADN00_09870"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="529" mass="58261" checksum="494DAAC2A9AB752F" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XLE5</accession>
    <name>A0A0P6XLE5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Metallophos domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10355</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77071">
        <property type="protein sequence ID" value="KPL77071"/>
        <property type="gene ID" value="ADN00_10355"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2537"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="1">
        <location>
            <begin position="40"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="269" mass="29778" checksum="CBAF6A0F290BFD10" modified="2016-01-20" version="1">MVGLGGALAASYPVFIERYWVTVNRYRVALPGLPPAFDGLRVAHLSDIHAGPWSPDGWLQGLMRTVMDLRADLIVCTGDYVREKNGTTQIERIWPLLAGLQAPLGVYSVLGNHDHWADTDRSLYWLEKSGQNLRHKVVRLERDGQPLWLAGAGDLWEDELGLEETLANIPPDEARVVLAHNPDSFDVPFSGRVDLMLCGHTHGGQVRLPLIGAPMLPVNNKAYVSGLLHLSRGAMFISRGIGWSGVPVRFNCSPEIALLELEYKKTMND</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XM41</accession>
    <name>A0A0P6XM41_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_18085</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL69982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064448.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL69982">
        <property type="protein sequence ID" value="KPL69982"/>
        <property type="gene ID" value="ADN00_18085"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL69982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="150" mass="16845" checksum="154065B1BFFF924E" modified="2016-01-20" version="1">MNNSSICLEIIAAPIACKDGIKDSWREVAEWLAGQIKARYGDLAQVNYFDLFDPNCPAFPSGAQLPIVKVEGRVISNGEKISLPLICKEIDGFIRHEGLDTEMGTSHLCSKIMRYNPVKVTSNAKFFYKEVLLNQLNSLKQSLFTLIAYW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XML6</accession>
    <name>A0A0P6XML6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_00775</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the fructosamine kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061042.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00775"/>
    <dbReference type="EnsemblBacteria" id="KPL81092">
        <property type="protein sequence ID" value="KPL81092"/>
        <property type="gene ID" value="ADN00_00775"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3553"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016477">
        <property type="entry name" value="Fructo-/Ketosamine-3-kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12149">
        <property type="entry name" value="PTHR12149"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03881">
        <property type="entry name" value="Fructosamin_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006221">
        <property type="entry name" value="Ketosamine-3-kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR006221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL81092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="305" mass="34567" checksum="C44C5402EBD0C20B" modified="2016-01-20" version="1">MSDFPVPLEDRIREALQRCGDFSAWKSLVRVGGGCISQSARLDTEEAVYFVKWNPRPFPKMFQIEAESLAYLASTHSVNVPKVYAWGEKEGALPGFLLVEWVGGAAGGGVGHHHRLLGEQLAVLHRCTSEKYGNRFGLWYDNYIGSNPQLNTWSGSWVDFFRDCRLKPQFDLAVRQGRMPGKRKRLLEKGMDHLDQFLGGRDIQPSLLHGDLWGGNFIVGINDQPYLIDPAIFFGDREADLAFTELFGGFSRDFYDAYQTAWPLDPQYAERKSIYNLYHLLNHLNLFGESYGSSVDAILSHFFGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XNM4</accession>
    <name>A0A0P6XNM4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_09785</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062818.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76883">
        <property type="protein sequence ID" value="KPL76883"/>
        <property type="gene ID" value="ADN00_09785"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2414"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018668">
        <property type="entry name" value="DNA-binding_VF530-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036361">
        <property type="entry name" value="SAP_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09905">
        <property type="entry name" value="VF530"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="74" mass="8763" checksum="F221CC357A20348A" modified="2016-01-20" version="1">MNPNPQPNNPLHGITLEMMLTQLVEQYGWAELSKRVPIRCFYNEPSIKSSLKFLRRTPWARKSVEDLYLQFIVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XNU9</accession>
    <name>A0A0P6XNU9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_07265</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062316.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78260">
        <property type="protein sequence ID" value="KPL78260"/>
        <property type="gene ID" value="ADN00_07265"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="91" mass="10228" checksum="5DDA26BF61E7705E" modified="2016-01-20" version="1">MTAQTDLEEARQRAEKVKQQFEDQLMSKANVVGVGVGFRRQRSTWTHEIAIVVMVSQKIPLHLLPANDRLPTEIDGVPVDVQEVGSFQIQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQ24</accession>
    <name>A0A0P6XQ24_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">PMT_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ADN00_13655</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063581.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000032.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13655"/>
    <dbReference type="EnsemblBacteria" id="KPL74342">
        <property type="protein sequence ID" value="KPL74342"/>
        <property type="gene ID" value="ADN00_13655"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038731">
        <property type="entry name" value="RgtA/B/C-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13231">
        <property type="entry name" value="PMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="65"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="104"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="127"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="196"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="255"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="287"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="313"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="344"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="domain" description="PMT_2" evidence="9">
        <location>
            <begin position="56"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL74342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="495" mass="54165" checksum="9FF34A6CE2E02AC7" modified="2016-01-20" version="1">MKKKTGWLLAILAMAAGLRLLLIGTRSIQYDDAFSLLLAERSLLEIVQGTAADTMPPLFYFLLHFWGLIQPGIVFARLLSVLLSLGTVWLVYELVRLVSGSERGGLAAAFLAAVSPLQIYHAQDIRMYALVMLTEAGYLVCFFHWIRAKNGARRRSLFAAGMILCAAAALYSHNLAGFGLIVPNAYLLLKRDWKNLGRLLALQLLVGVFFAPWLVYLPGQLQKIQAAFWTPRPGVIELVQALVMLVASLPLPGVWLWAGVLIALQVVVLTAIEAARLYRKEAQTRDALVFFGLLLLLPPALLFGVSYLIRPVFVPRGFLISSAGLLGLAGLVIARQWKAGGGKLLLGLFVLAAVISIPYQITYQAFPRSPFAEAAAYLSESQRPGDVIVNDNKLSHFPLAVYAPELEMKFLADEVGSANDTLAPATQAAMDLTAEGSIAAAAGSADRLRFIVFAKTLEEYAQMGSAHPAIRWLEMNYALTSKEVFGDLEVRTYER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XR54</accession>
    <name>A0A0P6XR54_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_16565</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064154.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16565"/>
    <dbReference type="EnsemblBacteria" id="KPL72085">
        <property type="protein sequence ID" value="KPL72085"/>
        <property type="gene ID" value="ADN00_16565"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3755"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="8"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="348" mass="38173" checksum="EDADC4EF47B57694" modified="2016-01-20" version="1">MSKVLTITQPRQLGFETIEDRGLNEKEVRVRTLYSGISAGTEMATYRGSSPFLHKQWNANVRLFLPADAPSLTYPQTGWGYEEVGEVIETSPDVTALKVGDIVYGTWGHRTHTVLKEDYASQRIKPLNLDPVLAIYSHIGPIALNGILDANIHIGETVAVFGLGVLGQVIAQLAKRSGAQVIGIDLIENRLELAKNLGADYVINPRSESAAEKIKELTHSRGADVCIEVSGSSRALNEAIRAAAYAARVVALGFFQGEAQGLYLGEEFHHNRIQLICSQIGNVNPALSHRWDRLRLIHTIMDLQAAGVLNLRPVITHVIPFQQAAQGFQILDETPDQALQIVLDFSNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XRC3</accession>
    <name>A0A0P6XRC3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Formate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">ADN00_15420</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mo-bis(molybdopterin guanine dinucleotide)</name>
            <dbReference type="ChEBI" id="CHEBI:60539"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the prokaryotic molybdopterin-containing oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72213.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063926.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15420"/>
    <dbReference type="EnsemblBacteria" id="KPL72213">
        <property type="protein sequence ID" value="KPL72213"/>
        <property type="gene ID" value="ADN00_15420"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.786"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008863">
        <property type="term" value="F:formate dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043546">
        <property type="term" value="F:molybdopterin cofactor binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015942">
        <property type="term" value="P:formate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02790">
        <property type="entry name" value="MopB_CT_Formate-Dh_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02753">
        <property type="entry name" value="MopB_Formate-Dh-H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009010">
        <property type="entry name" value="Asp_de-COase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041925">
        <property type="entry name" value="CT_Formate-Dh_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041924">
        <property type="entry name" value="Formate_Dh-H_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006478">
        <property type="entry name" value="Formate_DH_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006657">
        <property type="entry name" value="MoPterin_dinucl-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006656">
        <property type="entry name" value="Mopterin_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006963">
        <property type="entry name" value="Mopterin_OxRdtase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027467">
        <property type="entry name" value="MopterinOxRdtase_cofactor_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000283">
        <property type="entry name" value="NADH_UbQ_OxRdtase_75kDa_su_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00037">
        <property type="entry name" value="Fer4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04879">
        <property type="entry name" value="Molybdop_Fe4S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00384">
        <property type="entry name" value="Molybdopterin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01568">
        <property type="entry name" value="Molydop_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00926">
        <property type="entry name" value="Molybdop_Fe4S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50692">
        <property type="entry name" value="SSF50692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01591">
        <property type="entry name" value="Fdh-alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51085">
        <property type="entry name" value="2FE2S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51669">
        <property type="entry name" value="4FE4S_MOW_BIS_MGD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00641">
        <property type="entry name" value="COMPLEX1_75K_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00551">
        <property type="entry name" value="MOLYBDOPTERIN_PROK_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="10" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7 10" id="KW-0408">Iron</keyword>
    <keyword evidence="8 10" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0520">NAD</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="2Fe-2S ferredoxin-type" evidence="11">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="12">
        <location>
            <begin position="138"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="12">
        <location>
            <begin position="181"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S Mo/W bis-MGD-type" evidence="13">
        <location>
            <begin position="217"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="227"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51669"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KPL72213.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="920" mass="101433" checksum="402117F89DFE4DD3" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XSW5</accession>
    <name>A0A0P6XSW5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glyco_hydro_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_11675</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063195.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11675"/>
    <dbReference type="EnsemblBacteria" id="KPL76015">
        <property type="protein sequence ID" value="KPL76015"/>
        <property type="gene ID" value="ADN00_11675"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133204" description="Glyco_hydro_3 domain-containing protein" evidence="3">
        <location>
            <begin position="18"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="840"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="870"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="903"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_3" evidence="4">
        <location>
            <begin position="49"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL76015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="935" mass="101413" checksum="867E06377AF419DA" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XSY6</accession>
    <name>A0A0P6XSY6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">S-methyl-5'-thioadenosine phosphorylase</fullName>
            <ecNumber evidence="3">2.4.2.28</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">5'-methylthioadenosine phosphorylase</fullName>
            <shortName evidence="3">MTA phosphorylase</shortName>
            <shortName evidence="3">MTAP</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">mtnP</name>
        <name evidence="5" type="ORF">ADN00_07035</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the reversible phosphorylation of S-methyl-5'-thioadenosine (MTA) to adenine and 5-methylthioribose-1-phosphate. Involved in the breakdown of MTA, a major by-product of polyamine biosynthesis. Responsible for the first step in the methionine salvage pathway after MTA has been generated from S-adenosylmethionine. Has broad substrate specificity with 6-aminopurine nucleosides as preferred substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>phosphate + S-methyl-5'-thioadenosine = adenine + S-methyl-5-thio-alpha-D-ribose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:11852"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58533"/>
            <dbReference type="EC" id="2.4.2.28"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; S-methyl-5-thio-alpha-D-ribose 1-phosphate from S-methyl-5'-thioadenosine (phosphorylase route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homohexamer. Dimer of a homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.28" evidence="3"/>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062275.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07035"/>
    <dbReference type="EnsemblBacteria" id="KPL78227">
        <property type="protein sequence ID" value="KPL78227"/>
        <property type="gene ID" value="ADN00_07035"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3224"/>
    <dbReference type="UniPathway" id="UPA00904">
        <property type="reaction ID" value="UER00873"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017061">
        <property type="term" value="F:S-methyl-5-thioadenosine phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019509">
        <property type="term" value="P:L-methionine salvage from methylthioadenosine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09010">
        <property type="entry name" value="MTAP_SsMTAPII_like_MTIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01963">
        <property type="entry name" value="MTAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010044">
        <property type="entry name" value="MTAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018099">
        <property type="entry name" value="Purine_phosphorylase-2_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42679">
        <property type="entry name" value="PTHR42679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="SSF53167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01694">
        <property type="entry name" value="MTAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01240">
        <property type="entry name" value="PNP_MTAP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PNP_UDP_1" evidence="4">
        <location>
            <begin position="7"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphate binding" evidence="3">
        <location>
            <begin position="55"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphate binding" evidence="3">
        <location>
            <begin position="88"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="210"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="3">
        <location>
            <position position="168"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="3">
        <location>
            <position position="223"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL78227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="288" mass="31395" checksum="40C2594B6D2A968A" modified="2016-01-20" version="1">MTAQPILAVIGGSGLYQFEGLQDVETIEVDTPYGKPSSPIVMGTLAGKTVAFLARHGIGHFISPTEVNYRANIYALKSIGARRIVSISACGSLREDYAPGHIVIPDQLIDFTRDRKRSFFENGLVAHISPADPFCNEISTEIYQAVIQTSAVCHLGGSFITIEGPRFSTKGESNLFRAWGISIIGMTTSPEAFLAREAEMCYGVLAHVTDYDVWHTSEAPVSVEMVVRTLQENTHHAQEAIHNLVSALPEDFDCKCSRALANALMTNPPAIPAGTRQQLGWLIDKYLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XT94</accession>
    <name>A0A0P6XT94_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Heme ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_07595</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062378.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07595"/>
    <dbReference type="EnsemblBacteria" id="KPL78309">
        <property type="protein sequence ID" value="KPL78309"/>
        <property type="gene ID" value="ADN00_07595"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="5"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="258"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL78309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="519" mass="56779" checksum="7588EC489606B72E" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XV71</accession>
    <name>A0A0P6XV71_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH marR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_04550</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061771.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79132">
        <property type="protein sequence ID" value="KPL79132"/>
        <property type="gene ID" value="ADN00_04550"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01047">
        <property type="entry name" value="MarR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="14"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="162" mass="18722" checksum="32340234C8747A37" modified="2016-01-20" version="1">MTSNEQVQPDKPLQHVIWETVPLLARQIHQQADRAILQEYEMTRSQFHVLLQISHGRNTISSLANQDSISLPAVSRQVDELERKRLVTRQRDPQDRRIVHLALTDEGRQLKEIIRARVLEWLTSVVEPLSPAEQESIRQGLNQLASIFTDETNTCPHCHKPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XV78</accession>
    <name>A0A0P6XV78_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Aldehyde dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_04605</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061782.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04605"/>
    <dbReference type="EnsemblBacteria" id="KPL79141">
        <property type="protein sequence ID" value="KPL79141"/>
        <property type="gene ID" value="ADN00_04605"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.282"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016160">
        <property type="entry name" value="Ald_DH_CS_CYS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029510">
        <property type="entry name" value="Ald_DH_CS_GLU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00070">
        <property type="entry name" value="ALDEHYDE_DEHYDR_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00687">
        <property type="entry name" value="ALDEHYDE_DEHYDR_GLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="6">
        <location>
            <begin position="53"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="active site" evidence="3">
        <location>
            <position position="290"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL79141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="528" mass="57797" checksum="68644091A7D18AFB" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XVE9</accession>
    <name>A0A0P6XVE9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Diadenylate cyclase</fullName>
            <shortName evidence="10">DAC</shortName>
            <ecNumber evidence="10">2.7.7.85</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Cyclic-di-AMP synthase</fullName>
            <shortName evidence="10">c-di-AMP synthase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">dacA</name>
        <name evidence="12" type="ORF">ADN00_03975</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the condensation of 2 ATP molecules into cyclic di-AMP (c-di-AMP), a second messenger used to regulate differing processes in different bacteria.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>2 ATP = 3',3'-c-di-AMP + 2 diphosphate</text>
            <dbReference type="Rhea" id="RHEA:35655"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:71500"/>
            <dbReference type="EC" id="2.7.7.85"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="10">Probably a homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the adenylate cyclase family. DacA/CdaA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.85" evidence="10"/>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03975"/>
    <dbReference type="EnsemblBacteria" id="KPL79232">
        <property type="protein sequence ID" value="KPL79232"/>
        <property type="gene ID" value="ADN00_03975"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.151"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106408">
        <property type="term" value="F:diadenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006171">
        <property type="term" value="P:cAMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019932">
        <property type="term" value="P:second-messenger-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1700.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01499">
        <property type="entry name" value="DacA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014046">
        <property type="entry name" value="C-di-AMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034701">
        <property type="entry name" value="CdaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036888">
        <property type="entry name" value="DNA_integrity_DisA_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003390">
        <property type="entry name" value="DNA_integrity_scan_DisA_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02457">
        <property type="entry name" value="DAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004793">
        <property type="entry name" value="UCP004793"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143597">
        <property type="entry name" value="SSF143597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00159">
        <property type="entry name" value="TIGR00159"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51794">
        <property type="entry name" value="DAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 10" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="domain" description="DAC" evidence="11">
        <location>
            <begin position="84"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KPL79232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="293" mass="32544" checksum="D993113F77131A4B" modified="2016-01-20" version="1">MSELSFLFQRLSWQSALDIFLVTLIFFAVLWVVRDTQAQVLLRGVVFLIIVLSLFTSLVSLPAFSWLVRTTLPTLVLAIPVIFAPEIRRALEKLGRAGSGSLFWGQSKSQVQQIQESIRKIVTACARLSARQHGALIVLSRRDSLEEYLRTGVRLNADVSTELLLQIFYPNTPLHDGAVIVKGDKIIAASSVMPLSASGTLTRSPDRQMGLRHRAALGISEASDAIAVVVSEETGSISITHGGRMIRRLDSERLENILLAFYRPTEPENIPFFKSISQLVGRILPRGKPEDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XXY5</accession>
    <name>A0A0P6XXY5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Portal protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_07175</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062301.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07175"/>
    <dbReference type="EnsemblBacteria" id="KPL78246">
        <property type="protein sequence ID" value="KPL78246"/>
        <property type="gene ID" value="ADN00_07175"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1450">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02080">
        <property type="entry name" value="TrkA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02254">
        <property type="entry name" value="TrkA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51201">
        <property type="entry name" value="RCK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RCK N-terminal" evidence="1">
        <location>
            <begin position="2"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="2">
        <location>
            <begin position="136"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="222" mass="24404" checksum="5CC97577F3957AC4" modified="2016-01-20" version="1">MKVVVVGCGRLGAELANRLYQRHHEVTVVDKVGASFENLPAGFEGRMVEGDALNEDVLYRAGLEKASAVALVTNCDALNLVVGHTTREVYHIDTVVARNYDPDLRGLFEDFGIQVISSTSWGAQRVEEMLYHSEIRTVFSAGNGEIEVYEFAVPREIAGRCLLELMQDIEGAMIVSVTRAGKASHPEQDFRLESGDVLLLSASFDGISAFRNRVESLKKVEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XY54</accession>
    <name>A0A0P6XY54_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">D,D-heptose 1,7-bisphosphate phosphatase</fullName>
            <ecNumber evidence="5">3.1.3.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_00510</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the gmhB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.-" evidence="5"/>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060997.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00510"/>
    <dbReference type="EnsemblBacteria" id="KPL81052">
        <property type="protein sequence ID" value="KPL81052"/>
        <property type="gene ID" value="ADN00_00510"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3496"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006549">
        <property type="entry name" value="HAD-SF_hydro_IIIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004446">
        <property type="entry name" value="Heptose_bisP_phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006543">
        <property type="entry name" value="Histidinol-phos"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42891">
        <property type="entry name" value="PTHR42891"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004682">
        <property type="entry name" value="GmhB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01662">
        <property type="entry name" value="HAD-SF-IIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01656">
        <property type="entry name" value="Histidinol-ppas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="2 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Nucleophile" evidence="6">
        <location>
            <position position="8"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="6">
        <location>
            <position position="10"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="10"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="site" description="Stabilizes the phosphoryl group" evidence="7">
        <location>
            <position position="51"/>
        </location>
    </feature>
    <feature type="site" description="Contributes to substrate recognition" evidence="7">
        <location>
            <position position="101"/>
        </location>
    </feature>
    <feature type="site" description="Stabilizes the phosphoryl group" evidence="7">
        <location>
            <position position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00031828"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR004682"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR004682-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR004682-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR004682-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL81052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="185" mass="20400" checksum="B1D461D6313DB5BE" modified="2016-01-20" version="1">MNTAIFLDRDGVIIENRSDYVRSWLDVSIYHQALQALSMLSKLPVKIFVVTNQSAVGRGIIDLETVHQINQRLLEIIIQNNGRVDGFYICPHLPSDQCNCRKPEPGLILQAANQFQIDLANSILIGDALSDIQAAQNAGILNTYLVRTGRGAEQEAMLRDSPISGCVICNDLLTASRLIITKGQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XZ27</accession>
    <name>A0A0P6XZ27_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_06705</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000018">
        <property type="protein sequence ID" value="KPL78411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062209.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000018.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78411">
        <property type="protein sequence ID" value="KPL78411"/>
        <property type="gene ID" value="ADN00_06705"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="173" mass="18910" checksum="00F4BF268A9EED2B" modified="2016-01-20" version="1">MEDNRHPRSWSVSAASLLPLWLLALAVSAEGFPPAPISVQAAMGLFLAAVAIAMLLLWKKWIGPAVVLSYNIPFAFLYLLDEISTVYKTPFILVCTLIVSVGILLYQRSGRLTRGWMLLAAAAFVSLAVAAHSAGNFWQMTDQLGYYQCFPDALGCPPLAGRGDPWWLLLISL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y300</accession>
    <name>A0A0P6Y300_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATPase AAA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_11685</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063196.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11685"/>
    <dbReference type="EnsemblBacteria" id="KPL76016">
        <property type="protein sequence ID" value="KPL76016"/>
        <property type="gene ID" value="ADN00_11685"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3812"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="2">
        <location>
            <begin position="173"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL76016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="449" mass="50944" checksum="DB5C40D675FDBFEC" modified="2016-01-20" version="1">MYPTSEKKPQPAERPAAAPTAAFSPAPITKIEETGLPLLWLQDHVLKVMYFQGYMTGFKVAEDVSLPFSGVVDQILEILKREKLIEVRSSQLGLGEGSYQYAITGAGIEKAREALERSQYAGPAPVPLTDYIESCKKQSRGRVQVTNRVMRQMLTHLTLSEKTIQRLGPAINSGTSIFMYGPTGDGKTSIARAIGNLVQSQTMYIPYSIYVDGQVIKLYDSVNHRLAAGQETTSLGTGTLRAGTRRDPRWVNIKRPFIMVGGELTLAGLDLVFDDVLKYYEAPFQMKANGGILLIDDFGRQQVRPRDLLNRWIVPLENRIDFLTLHTGRKMEVPFDTLIIFSTNLPPKELVDEAFLRRLRHKIEIGDPTYEEYREIFKTVAEHKGVKYNDQTLAYLIQEWYIKRNRKVRASHPRDLCDQILDISRYLNVDAEMTRELIDMAADSYFVDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y3B5</accession>
    <name>A0A0P6Y3B5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Iron-sulfur cluster carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_02855</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the Mrp/NBP35 ATP-binding proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000013">
        <property type="protein sequence ID" value="KPL79407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02855"/>
    <dbReference type="EnsemblBacteria" id="KPL79407">
        <property type="protein sequence ID" value="KPL79407"/>
        <property type="gene ID" value="ADN00_02855"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140663">
        <property type="term" value="F:ATP-dependent FeS chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02040">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019591">
        <property type="entry name" value="Mrp/NBP35_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044304">
        <property type="entry name" value="NUBPL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033756">
        <property type="entry name" value="YlxH/NBP35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42961">
        <property type="entry name" value="PTHR42961"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10609">
        <property type="entry name" value="ParA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="30"/>
            <end position="37"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL79407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="266" mass="27814" checksum="2496023793B0CDB3" modified="2016-01-20" version="1">MKSITRRADVRLPQLKQFNQVGQVILVMSGKGGVGKSSIAALLAASLSRQGAKTGLLDADITGPSIPKLFGLPPGGLRGGELGMLPAVTPGGVRVVSTNLLLKEADLPTVWRGPLIAATIRQFWGDTIWGKLDTLIVDLPPGTSDAAIAVLNYLPVSGAVVVTTPQELAGLVVRKALKLLQNKEVPLLALVENMSYFTDSQGAKIEVFGPSHLDDLADLTGSAPRIQIPILPALSQAADAGAVETIHLPEIDRIAALLRSTPSPNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y3F2</accession>
    <name>A0A0P6Y3F2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">30S ribosomal protein S11</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rpsK</name>
        <name evidence="9" type="ORF">ADN00_12480</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Located on the platform of the 30S subunit, it bridges several disparate RNA helices of the 16S rRNA. Forms part of the Shine-Dalgarno cleft in the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the 30S ribosomal subunit. Interacts with proteins S7 and S18. Binds to IF-3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the universal ribosomal protein uS11 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063346.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12480"/>
    <dbReference type="EnsemblBacteria" id="KPL76144">
        <property type="protein sequence ID" value="KPL76144"/>
        <property type="gene ID" value="ADN00_12480"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3977"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01310">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001971">
        <property type="entry name" value="Ribosomal_S11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019981">
        <property type="entry name" value="Ribosomal_S11_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018102">
        <property type="entry name" value="Ribosomal_S11_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036967">
        <property type="entry name" value="Ribosomal_S11_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11759">
        <property type="entry name" value="PTHR11759"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00411">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002131">
        <property type="entry name" value="Ribosomal_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03632">
        <property type="entry name" value="uS11_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00054">
        <property type="entry name" value="RIBOSOMAL_S11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 7 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL76144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="134" mass="14243" checksum="91384D72FE225D25" modified="2016-01-20" version="1">MAQSVRSTRRGGAPRKIKRSLSSAQVHIFASFNNTIVTVTDQQGNAVCWASSGSAGFKGSRKSTPFAARLAAEQAIKSAQTMGVQEVDIIIKGPGPGRESAIRAIQGMGMKVRSISDVTPVPHNGCRPPKKRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y498</accession>
    <name>A0A0P6Y498_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable septum site-determining protein MinC</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">minC</name>
        <name evidence="6" type="ORF">ADN00_02245</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Cell division inhibitor that blocks the formation of polar Z ring septums. Rapidly oscillates between the poles of the cell to destabilize FtsZ filaments that have formed before they mature into polar Z rings. Prevents FtsZ polymerization.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Interacts with MinD and FtsZ.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the MinC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000009">
        <property type="protein sequence ID" value="KPL79809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061335.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000009.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02245"/>
    <dbReference type="EnsemblBacteria" id="KPL79809">
        <property type="protein sequence ID" value="KPL79809"/>
        <property type="gene ID" value="ADN00_02245"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2771"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000902">
        <property type="term" value="P:cell morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901891">
        <property type="term" value="P:regulation of cell septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00267">
        <property type="entry name" value="MinC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016098">
        <property type="entry name" value="CAP/MinC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013033">
        <property type="entry name" value="MinC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036145">
        <property type="entry name" value="MinC_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005526">
        <property type="entry name" value="Septum_form_inhib_MinC_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34108">
        <property type="entry name" value="PTHR34108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03775">
        <property type="entry name" value="MinC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63848">
        <property type="entry name" value="SSF63848"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01222">
        <property type="entry name" value="minC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="1 4" id="KW-0132">Cell division</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0717">Septation</keyword>
    <feature type="domain" description="MinC_C" evidence="5">
        <location>
            <begin position="124"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF03775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL79809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="231" mass="24832" checksum="EA4DA95532F98580" modified="2016-01-20" version="1">MTEENLVKVQIKGIREGLHVSVGDGPWENVEASLLNHIQQKESFFKGARIALEVGSHILHAAELGALRDKLSDHGVSLWAVISDSPTTERSAQNMGLATRLSSPKPDRVVKALDTSLAGDSAVMVRRTLRSGFRIETEGHVVVIGDVNPGAQIIAGGNIVVWGRLRGMVHAGCAGDAQAMICALEMSPTHLRIADVIAANVKKKKNPQPEVAYISDGQVVAENWNVKERGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y601</accession>
    <name>A0A0P6Y601_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Malate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01025</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000003">
        <property type="protein sequence ID" value="KPL80806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061105.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01025"/>
    <dbReference type="EnsemblBacteria" id="KPL80806">
        <property type="protein sequence ID" value="KPL80806"/>
        <property type="gene ID" value="ADN00_01025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1530.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043144">
        <property type="entry name" value="Mal/L-sulf/L-lact_DH-like_ah"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043143">
        <property type="entry name" value="Mal/L-sulf/L-lact_DH-like_NADP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036111">
        <property type="entry name" value="Mal/L-sulfo/L-lacto_DH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003767">
        <property type="entry name" value="Malate/L-lactate_DH-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11091">
        <property type="entry name" value="PTHR11091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02615">
        <property type="entry name" value="Ldh_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89733">
        <property type="entry name" value="SSF89733"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="361" mass="38838" checksum="336ECD94AB6227A1" modified="2016-01-20" version="1">MPDPLRFSVEDLNDYIVRFFTRLGVSPTDAQTAARVILAADLRGVDSHGIIRLHSYYGSRLLNGTINPQTAIKVLRETPVTLALDGGNGLGQVVGEYAMRRCIEKARANAIGMVTVRCSNHYGIAGYYAMMALEHNLIGVSFTNSQPLVAPTYGRTRLLGTNPIAVAVPAGKHLPYVLDMATSIVPIGRIAVYEKMGQPVPLGWGLDENGVPTSDPHAIQNGGALFPLGGPAETRGYKGYGLSLLVDLFCGVLAGAAIGPEVGDPSNQIPGANVGHFFAAIDISAFRDPQEFQHEMDRYIELLKKAPKAVGEERIYIHGEKEFEMAEVNQREGIPLLPAVVDSLREAGALVGEPFDLQPLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y6N6</accession>
    <name>A0A0P6Y6N6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alkylhydroperoxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_00755</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061039.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00755"/>
    <dbReference type="EnsemblBacteria" id="KPL81089">
        <property type="protein sequence ID" value="KPL81089"/>
        <property type="gene ID" value="ADN00_00755"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3549"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004675">
        <property type="entry name" value="AhpD_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003779">
        <property type="entry name" value="CMD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02627">
        <property type="entry name" value="CMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="SSF69118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00778">
        <property type="entry name" value="ahpD_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMD" evidence="1">
        <location>
            <begin position="31"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL81089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="123" mass="13949" checksum="887FF3821E3DF0A7" modified="2016-01-20" version="1">MSKSDRLAEFESYRQQMNERIAQIDRLGIKRFFNLDSSAYKDGALSGKEKELLGLVASMVLRCNHCIDYHILQCVDAGWSDEELVDAFNVALIVGGSIVIPHLRHAVESLDLARLRKIEDKDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y922</accession>
    <name>A0A0P6Y922_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">L-lactate dehydrogenase</fullName>
            <shortName evidence="6">L-LDH</shortName>
            <ecNumber evidence="4 6">1.1.1.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ldh</name>
        <name evidence="12" type="ORF">ADN00_07185</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the conversion of lactate to pyruvate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>(S)-lactate + NAD(+) = H(+) + NADH + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:23444"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16651"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.27"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="6">Allosterically activated by fructose 1,6-bisphosphate (FBP).</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 6">Fermentation; pyruvate fermentation to lactate; (S)-lactate from pyruvate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the LDH/MDH superfamily. LDH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.27" evidence="4 6"/>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062302.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07185"/>
    <dbReference type="EnsemblBacteria" id="KPL78247">
        <property type="protein sequence ID" value="KPL78247"/>
        <property type="gene ID" value="ADN00_07185"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3257"/>
    <dbReference type="UniPathway" id="UPA00554">
        <property type="reaction ID" value="UER00611"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004459">
        <property type="term" value="F:L-lactate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00488">
        <property type="entry name" value="Lactate_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001557">
        <property type="entry name" value="L-lactate/malate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011304">
        <property type="entry name" value="L-lactate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018177">
        <property type="entry name" value="L-lactate_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022383">
        <property type="entry name" value="Lactate/malate_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001236">
        <property type="entry name" value="Lactate/malate_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015955">
        <property type="entry name" value="Lactate_DH/Glyco_Ohase_4_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02866">
        <property type="entry name" value="Ldh_1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00056">
        <property type="entry name" value="Ldh_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000102">
        <property type="entry name" value="Lac_mal_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00086">
        <property type="entry name" value="LLDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56327">
        <property type="entry name" value="SSF56327"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01771">
        <property type="entry name" value="L-LDH-NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00064">
        <property type="entry name" value="L_LDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0520">NAD</keyword>
    <keyword evidence="6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ldh_1_N" evidence="10">
        <location>
            <begin position="9"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="Ldh_1_C" evidence="11">
        <location>
            <begin position="150"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="125"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="153"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6 7">
        <location>
            <position position="180"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="19"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="84"/>
            <end position="85"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 8">
        <location>
            <position position="93"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="123"/>
            <end position="125"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>beta-D-fructose 1,6-bisphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <note>allosteric activator</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>beta-D-fructose 1,6-bisphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <note>allosteric activator</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="modified residue" description="Phosphotyrosine" evidence="6">
        <location>
            <position position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000102-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KPL78247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="319" mass="34679" checksum="F24E718B249057FA" modified="2016-01-20" version="1">MNVSTHNPTRVAIIGTGNVGATFAYALMLSGLAAEIVLIDVNKSKAQGEAMDLNHAVPLAHPTRIWSGTYEDCAGAVLTVVTAGAAQKPGETRLDLVQRNTAIFRSIIPEIVKYNPDGLILIATNPVDILTYVSWKLSGLPKKRVIGSGTILDTARFRYLLSEHFDVDPRSVHAYIVGEHGDSEVPVWSLANIAGMRLPMFCAANGMSCQDDALDHIFQQTRDAAYEIIERKGSTYYAIGTGLVRIAEAIIRDQSTVLSISSYIEDYYGIDDVYISLPTIVDRGGAERTLRLELSNEEIAGLQNSAKVLKEIISQLNLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y983</accession>
    <name>A0A0P6Y983_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 13 15">tRNA (guanine-N(1)-)-methyltransferase</fullName>
            <ecNumber evidence="6 13 15">2.1.1.228</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="13">M1G-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="13">tRNA [GM37] methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="primary">trmD</name>
        <name evidence="17" type="ORF">ADN00_07615</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 13 15">Specifically methylates guanosine-37 in various tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 13 15">
            <text>guanosine(37) in tRNA + S-adenosyl-L-methionine = H(+) + N(1)-methylguanosine(37) in tRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:36899"/>
            <dbReference type="Rhea" id="RHEA-COMP:10145"/>
            <dbReference type="Rhea" id="RHEA-COMP:10147"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:73542"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="EC" id="2.1.1.228"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5 13 15">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 13 15">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 13 15">Belongs to the RNA methyltransferase TrmD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.228" evidence="6 13 15"/>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062381.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07615"/>
    <dbReference type="EnsemblBacteria" id="KPL78311">
        <property type="protein sequence ID" value="KPL78311"/>
        <property type="gene ID" value="ADN00_07615"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3351"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052906">
        <property type="term" value="F:tRNA (guanine(37)-N(1))-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd18080">
        <property type="entry name" value="TrmD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1270.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00605">
        <property type="entry name" value="TrmD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002649">
        <property type="entry name" value="tRNA_m1G_MeTrfase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023148">
        <property type="entry name" value="tRNA_m1G_MeTrfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016009">
        <property type="entry name" value="tRNA_MeTrfase_TRMD/TRM10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46417">
        <property type="entry name" value="PTHR46417"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01746">
        <property type="entry name" value="tRNA_m1G_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000386">
        <property type="entry name" value="tRNA_mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00088">
        <property type="entry name" value="trmD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 13 15" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 13 15" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 13 14" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="10 13 15" id="KW-0808">Transferase</keyword>
    <keyword evidence="12 13 15" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="tRNA_m1G_MT" evidence="16">
        <location>
            <begin position="23"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="13 14">
        <location>
            <begin position="132"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13 14">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00014679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000386-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="RuleBase" id="RU003464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF01746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KPL78311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="249" mass="27881" checksum="4D975A609E1CF863" modified="2016-01-20" version="1">MRFDVFTLFPEMFSSYLATSMLKRAAENRLIEVSLYNIRDWTTDKHHITDDTPYGGGGGMVMKPEPIFAAVESVLGAPPACPVILMTPQGRQFTQQVANELSGYERIGLLCGRYEGVDERVREHLVTDEISIGDFVLTGGELPAMVLIDALTRLIPGALGDPTGAEDDSFASGLLEYPHYTRPPEFRGWGVPAVLQSGNHAEIDRWRRERALERTLQRRPDLLEAMDLSKKDQAFLKKLREALSRSEDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YAC8</accession>
    <name>A0A0P6YAC8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF58 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_06100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06100"/>
    <dbReference type="EnsemblBacteria" id="KPL78796">
        <property type="protein sequence ID" value="KPL78796"/>
        <property type="gene ID" value="ADN00_06100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002881">
        <property type="entry name" value="DUF58"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01882">
        <property type="entry name" value="DUF58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="DUF58" evidence="2">
        <location>
            <begin position="217"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="460" mass="51711" checksum="DB2FB0570FBEAC17" modified="2016-01-20" version="1">MWTKGGFLKSLGKPFLCWFHFRAQNAEVHIHAQANALILLWLPALLWYALTLNAVPAVCFWSLTFSILFSYYWVRQNALFLNGRRELKYAAFQVGDLLEEEVRLENSSWVPVIWARFKDQSSIPGYTIRSVRTVSGQETSQFTSTTLCEQRGVYSLGPWTIQMADPLGLFLASQTYTDVKEIVVYPPLAVLPGHLLAHHQTRGDLRRMRQALEAETINASTVRAYHPGDPLKRVHWPSSARRQQLYIKTFEPETSSRVWLIPDLDAATQIGNGKDSTLEAAAILLASLANQLLRDRLAVGLFARDEQPRVVLPERGQAHLWTLLRAIAPLKAVKGQTLRKTIRESKALISENDLMVIITPSIETKWTEEIAVSARLRGVDVLLLDAQSFGAEFSARGALQSLVHRGIACQLVQKSDIRPLPASYGALRRWEFKTLGTGRVIVQQSPRSAGPRITRSNPLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YAN3</accession>
    <name>A0A0P6YAN3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Tryptophan synthase beta chain</fullName>
            <ecNumber evidence="12">4.2.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">trpB</name>
        <name evidence="14" type="ORF">ADN00_03370</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 12">The beta subunit is responsible for the synthesis of L-tryptophan from indole and L-serine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>(1S,2R)-1-C-(indol-3-yl)glycerol 3-phosphate + L-serine = D-glyceraldehyde 3-phosphate + H2O + L-tryptophan</text>
            <dbReference type="Rhea" id="RHEA:10532"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57912"/>
            <dbReference type="ChEBI" id="CHEBI:58866"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="4.2.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 12">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 12">Amino-acid biosynthesis; L-tryptophan biosynthesis; L-tryptophan from chorismate: step 5/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6 12">Tetramer of two alpha and two beta chains.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 12">Belongs to the TrpB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.20" evidence="12"/>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78951.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061552.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03370"/>
    <dbReference type="EnsemblBacteria" id="KPL78951">
        <property type="protein sequence ID" value="KPL78951"/>
        <property type="gene ID" value="ADN00_03370"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.24"/>
    <dbReference type="UniPathway" id="UPA00035">
        <property type="reaction ID" value="UER00044"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004834">
        <property type="term" value="F:tryptophan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00133">
        <property type="entry name" value="Trp_synth_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006316">
        <property type="entry name" value="Trp_synth_b-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006653">
        <property type="entry name" value="Trp_synth_b_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023026">
        <property type="entry name" value="Trp_synth_beta/beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48077:SF6">
        <property type="entry name" value="PTHR48077:SF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001413">
        <property type="entry name" value="Trp_syn_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500824">
        <property type="entry name" value="TrpB_prok"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01415">
        <property type="entry name" value="trpB_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00168">
        <property type="entry name" value="TRP_SYNTHASE_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 12" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 12" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="11 12 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="9 12" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 12" id="KW-0822">Tryptophan biosynthesis</keyword>
    <feature type="domain" description="PALP" evidence="13">
        <location>
            <begin position="77"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="12">
        <location>
            <position position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00009982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00011270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KPL78951.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="459" mass="50155" checksum="EFBEED76BECA448A" modified="2016-01-20" version="1">MSDQYRLLLNESDIPRQWYNAVADSPAAPAPVLNPQTKEPVTPEFLSALFPMELIMQEVSSDRFIDIPEEVREIYKLYRPTPLMRAIRLEKALGTPAHIYYKYEGASPSGSHKLNTAIPQAYFNKISGTKALTTETGAGQWGTALSISCSFFDMPLEVYMVRVSYDQKPYRRFLMEAYNAQVFASPTNLTQSGRAILAQDPNSPGSLGIAISEAVEVAALSNGQKKYSLGSVLNHVLIHQSVIGEEALKQMDMAGEYPDVVIGCVGGGSNFAGIAYPFLRENLRNGQRTRLLAVEPNATPSLTRGVYDFDYGDTAKMAPIVKMHTLGSDFIPAPIHAGGLRYHGMAPSLSSFYDQGLIEAIAVPQISTFEAGLLFAKTEAILPAPESAHAIRAAIDEALKAKETGEKRVILFNLSGHGNFDLSSYNAYLSGRLVDYDLPEEQISSIREHLPLSQSAPVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YBC8</accession>
    <name>A0A0P6YBC8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Pyruvate dehydrogenase E1 component subunit alpha</fullName>
            <ecNumber evidence="2 7">1.2.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pdhA</name>
        <name evidence="9" type="ORF">ADN00_03530</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>(R)-N(6)-lipoyl-L-lysyl-[dihydrolipoyllysine-residue acetyltransferase] + H(+) + pyruvate = (R)-N(6)-(S(8)-acetyldihydrolipoyl)-L-lysyl-[dihydrolipoyllysine-residue acetyltransferase] + CO2</text>
            <dbReference type="Rhea" id="RHEA:19189"/>
            <dbReference type="Rhea" id="RHEA-COMP:10480"/>
            <dbReference type="Rhea" id="RHEA-COMP:10481"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83111"/>
            <dbReference type="EC" id="1.2.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 7">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="7">Heterodimer of an alpha and a beta chain.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.4.1" evidence="2 7"/>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061879.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03530"/>
    <dbReference type="EnsemblBacteria" id="KPL79225">
        <property type="protein sequence ID" value="KPL79225"/>
        <property type="gene ID" value="ADN00_03530"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.57"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043231">
        <property type="term" value="C:intracellular membrane-bounded organelle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004739">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006086">
        <property type="term" value="P:acetyl-CoA biosynthetic process from pyruvate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017597">
        <property type="entry name" value="Pyrv_DH_E1_asu_subgrp-y"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03182">
        <property type="entry name" value="PDH_E1_alph_y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 7 9" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="E1_dh" evidence="8">
        <location>
            <begin position="12"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL79225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="323" mass="35974" checksum="A3000E841968427C" modified="2016-01-20" version="1">MEKQEYLDLYHQMVVIRKVEESAAELYQQGKIGGFLHLYIGQEAVSTGLVGARKPQDRLITAYRDHGLAINAGLSAKEVLAELLGKATGCSKGKGGSMHMASVEKNFWGGHAIVGAHLPLAAGLALGDQYSKTDGVTICMFGDGATNIGFFHEALNMSKVWKLPVLWVCENNRYGMGTAVERASAVSEIRQKAEGYGMKNDVVDGMDVMKVYEKSKEMIDDIRAGNGPQFLEIETYRFRGHSMGDPERYRKSEEVHQWQENDPIGVYRKYLMDRGIFTEEELNRQDELASEEVREAVAFAESSPDPDPEELFTDIYVENSVEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YBQ9</accession>
    <name>A0A0P6YBQ9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF1801 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_02730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000013">
        <property type="protein sequence ID" value="KPL79372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061427.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000013.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79372">
        <property type="protein sequence ID" value="KPL79372"/>
        <property type="gene ID" value="ADN00_02730"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2179"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014922">
        <property type="entry name" value="DUF1801"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08818">
        <property type="entry name" value="DUF1801"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF1801" evidence="1">
        <location>
            <begin position="26"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="138" mass="15791" checksum="D8AA6088D1BB03FE" modified="2016-01-20" version="1">MYELKTKINDQPVEAFLNKVEDPQKQQDSFAILDMMAEITGQPPRMWGDSLVGFGKYQYKYASGHQGEWFLVGFSPRKQNLTLYFMSGFDEYDGLVAKLGKYKTGKSCLYIKKLEDVNQGVLRELIELSIKLMRASSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YBR8</accession>
    <name>A0A0P6YBR8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Metallo-beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_02880</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000013">
        <property type="protein sequence ID" value="KPL79390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061453.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000013.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02880"/>
    <dbReference type="EnsemblBacteria" id="KPL79390">
        <property type="protein sequence ID" value="KPL79390"/>
        <property type="gene ID" value="ADN00_02880"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2211"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022712">
        <property type="entry name" value="Beta_Casp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011108">
        <property type="entry name" value="RMMBL"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10996">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07521">
        <property type="entry name" value="RMMBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01027">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="13"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-Casp" evidence="2">
        <location>
            <begin position="253"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="464" mass="52230" checksum="2C84AD33F97ADFA4" modified="2016-01-20" version="1">MQIHFHGAAQTVTGSKHLLEINGNLLLLDCGLFQGKRADTYTANQTFNFDPSDVDAVILSHAHIDHSGNLPNLVKNGFRGKIYATRGTARLSEIMLRDAGHIQEQDAVYVNKKRRRKGQPPVEPLYTVEDVERVLPLFETVDYDRPFEPFEGVTARFVEAGHILGSAAVVLDVRENGKQKRVWFSGDIGRYKLPLLRDPVLPQNTDYLLMESTYGDKLHRDPEAAYAEFVEVVARTIKRGGKVIIPAFAVGRTQELVYNLNRAIADQLLPHIPVYVDSPLAVGASDIFREFPEYFDQETWEFIDNGRHKALYFKELVYTRSVDESKAINDIHKPMVIISASGMAETGRILHHLRHNIEDPRSTILIVSWQAPDTLGRRLAEQAREVRIFGEEYYRRAEVATIGGLSAHAGQDLLLDYAAASRDTLKHIYLVHGEERGALPLMAKIREQHIAPVSFPGPKSVVEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YFN2</accession>
    <name>A0A0P6YFN2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Molybdenum cofactor biosynthesis protein B</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_00135</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">May be involved in the biosynthesis of molybdopterin.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 5">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the MoaB/Mog family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL80999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060930.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00135"/>
    <dbReference type="EnsemblBacteria" id="KPL80999">
        <property type="protein sequence ID" value="KPL80999"/>
        <property type="gene ID" value="ADN00_00135"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3423"/>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00886">
        <property type="entry name" value="MogA_MoaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012245">
        <property type="entry name" value="MoaB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036425">
        <property type="entry name" value="MoaB/Mog-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001453">
        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008284">
        <property type="entry name" value="MoCF_biosynth_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00994">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006443">
        <property type="entry name" value="MoaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00852">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53218">
        <property type="entry name" value="SSF53218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00177">
        <property type="entry name" value="molyb_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01078">
        <property type="entry name" value="MOCF_BIOSYNTHESIS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MoCF_biosynth" evidence="6">
        <location>
            <begin position="5"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR006443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL80999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="172" mass="18572" checksum="F9C73FF94587EB01" modified="2016-01-20" version="1">MPAVAILTISDRSSRGERPDLSGPALIEEVTRLGWQVADYSIVADDAEKIKAYLIEWCDKHVVQMILTTGGTGFAPRDVTPEATLAVIERSAPGLAEYMRMKSFEKTPHAMLSRAVAGIRKATLIVNLPGSPKAAVENFNFVSPVLPHAFQLLAEDASSEQGHIFTPGDKNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YFU8</accession>
    <name>A0A0P6YFU8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Phosphoglucomutase (alpha-D-glucose-1,6-bisphosphate-dependent)</fullName>
            <ecNumber evidence="4">5.4.2.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">ADN00_00695</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>alpha-D-glucose 1-phosphate = alpha-D-glucose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:23536"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="5.4.2.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.2" evidence="4"/>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061027.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00695"/>
    <dbReference type="EnsemblBacteria" id="KPL81081">
        <property type="protein sequence ID" value="KPL81081"/>
        <property type="gene ID" value="ADN00_00695"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3536"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004614">
        <property type="term" value="F:phosphoglucomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05801">
        <property type="entry name" value="PGM_like3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016066">
        <property type="entry name" value="A-D-PHexomutase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045244">
        <property type="entry name" value="PGM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005852">
        <property type="entry name" value="PGM_a-D-Glc-sp"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22573">
        <property type="entry name" value="PTHR22573"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="SSF53738"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="SSF55957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01132">
        <property type="entry name" value="pgm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00710">
        <property type="entry name" value="PGM_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGM_PMM_I" evidence="10">
        <location>
            <begin position="41"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_II" evidence="11">
        <location>
            <begin position="211"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_III" evidence="12">
        <location>
            <begin position="322"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_IV" evidence="9">
        <location>
            <begin position="491"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KPL81081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="550" mass="59341" checksum="CF98CF6E5AA60B33" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GL35</accession>
    <name>A0A0N8GL35_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Lysine--tRNA ligase</fullName>
            <ecNumber evidence="6">6.1.1.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Lysyl-tRNA synthetase</fullName>
            <shortName evidence="6">LysRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">lysS</name>
        <name evidence="9" type="ORF">ADN00_16985</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6 7">
            <text>ATP + L-lysine + tRNA(Lys) = AMP + diphosphate + L-lysyl-tRNA(Lys)</text>
            <dbReference type="Rhea" id="RHEA:20792"/>
            <dbReference type="Rhea" id="RHEA-COMP:9696"/>
            <dbReference type="Rhea" id="RHEA-COMP:9697"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78529"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6 7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6 7">Binds 3 Mg(2+) ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.6" evidence="6"/>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064244.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16985"/>
    <dbReference type="EnsemblBacteria" id="KPL71394">
        <property type="protein sequence ID" value="KPL71394"/>
        <property type="gene ID" value="ADN00_16985"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.457"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004824">
        <property type="term" value="F:lysine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006430">
        <property type="term" value="P:lysyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00775">
        <property type="entry name" value="LysRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd04322">
        <property type="entry name" value="LysRS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00252">
        <property type="entry name" value="Lys_tRNA_synth_class2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002313">
        <property type="entry name" value="Lys-tRNA-ligase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044136">
        <property type="entry name" value="Lys-tRNA-ligase_II_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018149">
        <property type="entry name" value="Lys-tRNA-synth_II_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00982">
        <property type="entry name" value="TRNASYNTHLYS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00499">
        <property type="entry name" value="lysS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="8">
        <location>
            <begin position="183"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="413"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL71394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="506" mass="58152" checksum="A053AA7E1104319B" modified="2016-01-20" version="1">MDLNELERNRYEKIARLRELGMEPYPTRSNPSHTTVEAMKAFEEAEAANPEARVEVTVAGRLRSMRPMGKISFAHVEDRAGRLQLFFRVNTLGEEKMTILRDLFDLGDYIQASGFLFRTKTGEISVHVEDFTMLAKAISPLPAAKDEVVDGKVVRHATLNDPETRFRQRYADLAVNSDVRKIFRLRTETVRAIREYLDNLDFIEVETPILQPIYGGAAARPFVTHHNQLKQDLYLRISFELYLKRLVVGMFDRVYEIGRDFRNEGVSFKHNPEFTQLEYYMAYADYLKVMEITENMVAHVADRVLGTRKATFKGNEIDLNPPWRRLELRQGLMDAVGIDIHAHREAESLAAAMQAKGIKPKPGAPWGKLVDQLLGDFLEPNLIQPTFLYDYPRDISPLAKSKPGDPQTVERFEGFVGGMELCNAFTELNDPLDQESRFLEMGRAYEDEDEERHPMDDDYLQAMKYGMPPQGGFGMGIDRLVMLLADKHSIREVILFPHLRDRDDEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GL45</accession>
    <name>A0A0N8GL45_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Phosphate ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">pstB</name>
        <name evidence="6" type="ORF">ADN00_17495</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064338.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17495"/>
    <dbReference type="EnsemblBacteria" id="KPL71474">
        <property type="protein sequence ID" value="KPL71474"/>
        <property type="gene ID" value="ADN00_17495"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015415">
        <property type="term" value="F:ATPase-coupled phosphate ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03260">
        <property type="entry name" value="ABC_PstB_phosphate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015850">
        <property type="entry name" value="ABC_transpr_PstB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005670">
        <property type="entry name" value="Phosp_transpt1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43423">
        <property type="entry name" value="PTHR43423"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43423:SF3">
        <property type="entry name" value="PTHR43423:SF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="9"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="42"/>
            <end position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL71474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="256" mass="28596" checksum="20137035E56153CB" modified="2016-01-20" version="1">MNSEPADIIQVRNLTLRYSDGKESLKDINLSIKANAINVLFGPANGGKSTLLRTLNRLNDLTDVSVMQGEVLFNGKNLLDPDIDVIELRRTIGIVFSRPVVLPMTIYENISYGLALAGIRSKVQQKERVKEALQQAVLWDEVYDRLDTPAAELSGGQKQRLCLARSLALKPEVIMLDEPTSALDPVSTANIEDLLQRIKEELTIILVPHNTQQAARMADYAAFFLQGELVEWGTGEQIFTRPKEKKTQDYVEGRFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GLC5</accession>
    <name>A0A0N8GLC5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_16215</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the binding-protein-dependent transport system permease family. FecCD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16215"/>
    <dbReference type="EnsemblBacteria" id="KPL72114">
        <property type="protein sequence ID" value="KPL72114"/>
        <property type="gene ID" value="ADN00_16215"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000522">
        <property type="entry name" value="ABC_transptr_permease_BtuC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30472">
        <property type="entry name" value="PTHR30472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01032">
        <property type="entry name" value="FecCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="110"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="142"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="232"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="271"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="301"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL72114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="328" mass="35140" checksum="5E999C0805612E9B" modified="2016-01-20" version="1">MKPAGFLLILAALLLAISLLSLFLGRYPQPGFISLERLNTDELARRVLLNLRAPRILAAVLLGMSLGAAGSVFQMIFSNPLVEPGFLGVSQGATFGAALAIIFLGGTPWITQGSAAVFAFGGLAVSYFLSRRVRFGGWVLRLVLAGIAVSALFSSGVGILKYIADPLEELPEITFWLLGGLYKINWQDLRVLLPVVVISLLILFQMRWRLNLLSLEDEVAFSLGLAPGRERALVLAASVAAAASVTAVSGIVSWVGLIVPHISRRLFGADARYSLPGAMLLGGIFTLVCDDLARTLMVAEVPLGIITSLFGALFFMLLMISRGIRVEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GLP5</accession>
    <name>A0A0N8GLP5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_14885</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000036">
        <property type="protein sequence ID" value="KPL73074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063824.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000036.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL73074">
        <property type="protein sequence ID" value="KPL73074"/>
        <property type="gene ID" value="ADN00_14885"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1840"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="6"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="255"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL73074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="506" mass="56002" checksum="D3D63A02D3720E44" modified="2016-01-20" version="1">MRNVILEFKAINKSFFGVQVLEGVSFQLEQGSVLGLIGENGAGKTTMMNILGGVIPYDSGELLLRGEHYRPENPGDAQKAGIGFIHQELNLFTNLSIAENLFIESFPRVKGMPFIDRKTIHDHTKEFLQMVDLEFSPDVLVERLSPGERQLVEIAKALSSDAQIIIFDEPTTSLTNRETERLFNIIERLKKDGRSIIYISHILGDVKRLADNILVLRDGSVVGGGSANDFDINRMISMMVGRDITQLYPSRKTAPTTTPVLSVNGLRQSGIVENINLQLHKKEILGMFGLMGSGRSELARIIFGLDPYESGEIVINGKKASRVNPRTSIANEIAFVTENRREEGLLMNLPVADNIGLVALPTYSTQRLRRVDRSRITKAIDDVTDLLKIKVANVHKSLAKGLSGGNQQKAVIGKWLLSRPSVLIVDEPTRGIDVGAKYEVYNIINDLSAEGACVLFISSELEELMGVCDRILVMSYGEITGEFVREEFNKESILRAAFRENGNGSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GLV5</accession>
    <name>A0A0N8GLV5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Segregation protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_14510</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000035">
        <property type="protein sequence ID" value="KPL73554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14510"/>
    <dbReference type="EnsemblBacteria" id="KPL73554">
        <property type="protein sequence ID" value="KPL73554"/>
        <property type="gene ID" value="ADN00_14510"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2067"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02195">
        <property type="entry name" value="SelD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.650.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010918">
        <property type="entry name" value="PurM-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036676">
        <property type="entry name" value="PurM-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016188">
        <property type="entry name" value="PurM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036921">
        <property type="entry name" value="PurM-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004536">
        <property type="entry name" value="SPS/SelD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10256">
        <property type="entry name" value="PTHR10256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00586">
        <property type="entry name" value="AIRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02769">
        <property type="entry name" value="AIRS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036407">
        <property type="entry name" value="Selenphspht_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55326">
        <property type="entry name" value="SSF55326"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56042">
        <property type="entry name" value="SSF56042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00476">
        <property type="entry name" value="selD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0711">Selenium</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="AIRS" evidence="4">
        <location>
            <begin position="28"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="AIRS_C" evidence="5">
        <location>
            <begin position="146"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL73554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="323" mass="34726" checksum="B831A9E70C75E7D1" modified="2016-01-20" version="1">MAQVLRPMENIFQSADYPDLLVGLDSPDDAAVWLVDEQRALVMTTDFFTPVVDDAYDYGAIAAANSLSDVYAMGGQPFLALNIAALPPDLPLEISSEIVRGGAEKAREAGVVIAGGHTIQDKEPKFGLVVIGWVDPHKMLTKNGARPGDLLVLTKPLSFGVVTTAMKQQKALPEEEAEVIGWMKQLNRGAAGLALEFGLHAGTDITGFSLLGHALEMANASKLGLRFDFEAIPILESALRCAKMGYFPGGAFNNLANFGEQVRYTRDLTEYEELILFDPQTSGGLLLCVPPEKIDAFMARAAQMDQPAWVIGEAREGSGIEVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GM56</accession>
    <name>A0A0N8GM56_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13790</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063606.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000032.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13790"/>
    <dbReference type="EnsemblBacteria" id="KPL74362">
        <property type="protein sequence ID" value="KPL74362"/>
        <property type="gene ID" value="ADN00_13790"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="48"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="151" mass="17307" checksum="0B77CB618287A251" modified="2016-01-20" version="1">MDILHLVDRLEELFNESRSVPFTHSVIVDEDLMLDIIDQMRVSIPEEIKKAQQLLAQKDRILAQAQEEANRTLALAREKSESVVERDSIVQAAQARAEQIIAQAKVEIENTKREADDYVLDTLTKLEMELDRSLNQVRNGIRTLSRPPESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMR1</accession>
    <name>A0A0N8GMR1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_11600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063181.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76002">
        <property type="protein sequence ID" value="KPL76002"/>
        <property type="gene ID" value="ADN00_11600"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="178" mass="20402" checksum="EA44050B7F43E4F4" modified="2016-01-20" version="1">MNHQPFEKWIFEEDDLTPKELELFSEHLEECNECTGLRASLHQVEQRLRVAPILAPSPGFADRWKASLAERTAREQQRQVRKFLTTLFLSGGLLFVLIFSQLLLTSSPTDWLITGIQFTTLSVLRFNQLPQVIMTFLQILPPAIPIVVWVFATVTFSLLGILWAGTIWRLSTRGVHNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMY3</accession>
    <name>A0A0N8GMY3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_11530</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063163.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11530"/>
    <dbReference type="EnsemblBacteria" id="KPL76578">
        <property type="protein sequence ID" value="KPL76578"/>
        <property type="gene ID" value="ADN00_11530"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00211">
        <property type="entry name" value="PTS_IIA_fru"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013196">
        <property type="entry name" value="HTH_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011608">
        <property type="entry name" value="PRD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036634">
        <property type="entry name" value="PRD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016152">
        <property type="entry name" value="PTrfase/Anion_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002178">
        <property type="entry name" value="PTS_EIIA_type-2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08279">
        <property type="entry name" value="HTH_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00874">
        <property type="entry name" value="PRD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00359">
        <property type="entry name" value="PTS_EIIA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55804">
        <property type="entry name" value="SSF55804"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63520">
        <property type="entry name" value="SSF63520"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51372">
        <property type="entry name" value="PRD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51094">
        <property type="entry name" value="PTS_EIIA_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="PRD" evidence="4">
        <location>
            <begin position="321"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="domain" description="PTS EIIA type-2" evidence="3">
        <location>
            <begin position="536"/>
            <end position="679"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL76578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="691" mass="79159" checksum="6B3BBEE360B397CF" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GN30</accession>
    <name>A0A0N8GN30_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10220</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76954">
        <property type="protein sequence ID" value="KPL76954"/>
        <property type="gene ID" value="ADN00_10220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="1067" mass="118446" checksum="31CCCE71EB113DE8" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GN78</accession>
    <name>A0A0N8GN78_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_09470</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062746.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09470"/>
    <dbReference type="EnsemblBacteria" id="KPL77338">
        <property type="protein sequence ID" value="KPL77338"/>
        <property type="gene ID" value="ADN00_09470"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901135">
        <property type="term" value="P:carbohydrate derivative metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05008">
        <property type="entry name" value="SIS_GlmS_GlmD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035466">
        <property type="entry name" value="GlmS/AgaS_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="SIS" evidence="2">
        <location>
            <begin position="48"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="2">
        <location>
            <begin position="216"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="380" mass="41556" checksum="3F59D7A38FE74AF4" modified="2016-01-20" version="1">MNLEQLKRKFPSGILRNQHPFYMADAIGDIPDCLQACISDELQRQIKAATSQVKPSKFMTIGCGTSYNACQAAAYFLQNLLKIPAIAYDAYDFELDTPPGIDENTMVIAISESGQSITTCLSLEKSKELGAFTVGISANPESRLAKSAHLAMTDPFLHEIPLGKTRTYLSTALLGMLAGVFTRGESEINLFISQISKAIDAIRDNSDIWQTDAKIIASDLPATQTRYIVTGFGAQKANADEIRLKIMEVLGESATSFGLEEFTHGPSACFKDDLTVILLQTDERTLKKAVRIAEGIVFSSVNLVVITDQMGAGWPEKAHTISIPKMDNARLFGMFPAVVAAQYLLYYLALNKGLNPDVNLEDIHPELGAIYAFFFPPGTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNF1</accession>
    <name>A0A0N8GNF1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribonuclease 3</fullName>
            <ecNumber evidence="6">3.1.26.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Ribonuclease III</fullName>
            <shortName evidence="6">RNase III</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rnc</name>
        <name evidence="10" type="ORF">ADN00_08555</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>Endonucleolytic cleavage to 5'-phosphomonoester.</text>
            <dbReference type="EC" id="3.1.26.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ribonuclease III family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.26.3" evidence="6"/>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08555"/>
    <dbReference type="EnsemblBacteria" id="KPL77922">
        <property type="protein sequence ID" value="KPL77922"/>
        <property type="gene ID" value="ADN00_08555"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.715"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004525">
        <property type="term" value="F:ribonuclease III activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00593">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00104">
        <property type="entry name" value="RNase_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014720">
        <property type="entry name" value="dsRBD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011907">
        <property type="entry name" value="RNase_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000999">
        <property type="entry name" value="RNase_III_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036389">
        <property type="entry name" value="RNase_III_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11207">
        <property type="entry name" value="PTHR11207"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00035">
        <property type="entry name" value="dsrm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14622">
        <property type="entry name" value="Ribonucleas_3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00358">
        <property type="entry name" value="DSRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00535">
        <property type="entry name" value="RIBOc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69065">
        <property type="entry name" value="SSF69065"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02191">
        <property type="entry name" value="RNaseIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50137">
        <property type="entry name" value="DS_RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00517">
        <property type="entry name" value="RNASE_3_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50142">
        <property type="entry name" value="RNASE_3_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="6" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="RNase III" evidence="9">
        <location>
            <begin position="1"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="DRBM" evidence="8">
        <location>
            <begin position="149"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="39"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="111"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL77922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="220" mass="24388" checksum="2BDC2D472E989454" modified="2016-01-20" version="1">MHLAFNDLLLVSRALTHRSYLNEHPEALEDNERLEFLGDAVLDFLVGAWLYNHFPEMPEGDLTRMRSALVHTEQLAEFARQINLGQALRLGRGEAQGGGRERSALLCDTFEALIGALYLDLGIDAVLKFISPLLEEASNDILINQKIEDPKSMFQEWVQAQGMPTPIYVTRNSFGPDHSKVFEVDVVVDDQVFGTGTGHGKQAATKAAAKDALQRLGLID</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNJ0</accession>
    <name>A0A0N8GNJ0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HisKA_7TM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_07090</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78234.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062285.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78234">
        <property type="protein sequence ID" value="KPL78234"/>
        <property type="gene ID" value="ADN00_07090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031621">
        <property type="entry name" value="HisKA_7TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16927">
        <property type="entry name" value="HisKA_7TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="218"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="284"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="HisKA_7TM" evidence="2">
        <location>
            <begin position="24"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78234.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="636" mass="70795" checksum="57F940FE413C5FCC" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNP2</accession>
    <name>A0A0N8GNP2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_05170</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SorC transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78650">
        <property type="protein sequence ID" value="KPL78650"/>
        <property type="gene ID" value="ADN00_05170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007324">
        <property type="entry name" value="Sugar-bd_dom_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04198">
        <property type="entry name" value="Sugar-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r4_2" evidence="3">
        <location>
            <begin position="20"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar-bind" evidence="2">
        <location>
            <begin position="67"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL78650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="328" mass="36056" checksum="59CE10887C036FA0" modified="2016-01-20" version="1">MWELVVEDFRDYEYARLISSVLTLYYFESLSQYQIAEQLGLSTAKVNRLLKQARQQGMVEIVLRTPFQTIFNLEQQFQSITGIKKAIIVPCLTENPEATTQLIGRAAANFLMEQIRDGDTICLGGGNGVRSVVQNITGRKIFDNITVVPALGGVQGRYETDVNNLAADLAQRLGAASYAFHAPAITDCAEERENLIQLRQVKEVLDIARGAQIALYGIGAVRPETASFFRFTSLREDEVKDLIADPNNTGEILAHILDPQGNVATPAFEQRVVGLGLPELDRIPLTIGIATSEEKVLPVVAAIRGGHVKALVTDEKTARAVIDLYQQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNQ8</accession>
    <name>A0A0N8GNQ8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_05970</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78778.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062056.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05970"/>
    <dbReference type="EnsemblBacteria" id="KPL78778">
        <property type="protein sequence ID" value="KPL78778"/>
        <property type="gene ID" value="ADN00_05970"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1672"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd08025">
        <property type="entry name" value="RNR_PFL_like_DUF711"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007841">
        <property type="entry name" value="UPF0210"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37560">
        <property type="entry name" value="PTHR37560"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05167">
        <property type="entry name" value="DUF711"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78778.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="459" mass="47493" checksum="6F141BA5CA36F7D6" modified="2016-01-20" version="1">MIRPEEIIHTIDMIQKENLDVRAVTMGISLLDCHRVDVHRTCEAIKEKIKRCAGSLVSTCDAISAEYAIPVVNKRIAVTPIAHVGAGFDAEGFVEIARALDEAASAVGVDFLGGFSADVANGVTIGDRALIDAIPQALTCTKKVCASVNVGATRYGINMDAIVLLGQTVKELAERSADSGGFAAAKFVVFTNQPGDNPFMAGAIHGLGQHEVVINVGVSGPGVIARALERKIAQVGSENLGLHDLAEEIKRTAFRVTRSGELIGRQVAQALNVPFGVVDLSLAPTPNVGDSVGEIMQILGVDAIGAPGSTAIIALLNDAVKKGGTFASQSVGGLSGAFIPVCEDQALANAVRDESLVLEKLEAMTSVCSVGLDMIAIPGSVDAATISAIIADEMAIGMINGKTTAVRLIPVPGKEAGEFVSFGGLFGESAIAPVRNAGKSARFVKFGGKIPAPIHSLRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNT8</accession>
    <name>A0A0N8GNT8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Asparagine synthetase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_03765</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061628.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03765"/>
    <dbReference type="EnsemblBacteria" id="KPL79018">
        <property type="protein sequence ID" value="KPL79018"/>
        <property type="gene ID" value="ADN00_03765"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.106"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004066">
        <property type="term" value="F:asparagine synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016783">
        <property type="term" value="F:sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006529">
        <property type="term" value="P:asparagine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01990">
        <property type="entry name" value="Alpha_ANH_like_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001962">
        <property type="entry name" value="Asn_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005232">
        <property type="entry name" value="LarE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43169:SF2">
        <property type="entry name" value="PTHR43169:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00733">
        <property type="entry name" value="Asn_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006661">
        <property type="entry name" value="PP-lp_UCP006661"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00268">
        <property type="entry name" value="TIGR00268"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Asparagine synthetase" evidence="2">
        <location>
            <begin position="23"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile and sulfur donor" evidence="1">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR006661-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="275" mass="30665" checksum="FF3AE09B9FB00903" modified="2016-01-20" version="1">MDEALRAKWDALQRWLGGFARPLVAFSGGVDSALLAFAARQAHGDQMLAVTVKSPLHTSQEIQRATAFAVAYGIPQRLIELNEMEREDFTHNAADRCYQCKALRFTEIVKLAASEGFDVVLEGSNADDAFDYRPGARAAKELDVRSPLAELNFTKAEIRAAAQTFNLPVWNLPSSPCLATRFAYGFPITPEGLIRVEKAESFLRELGLDNLRARVLNQQSLKIETAPDQFLTVLQKREQILAYFDSLGFANVSLDLKGYRRGSMNEDFDDQNCLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNU1</accession>
    <name>A0A0N8GNU1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_03900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79042">
        <property type="protein sequence ID" value="KPL79042"/>
        <property type="gene ID" value="ADN00_03900"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="77" mass="8807" checksum="81BA72FE3D8B400A" modified="2016-01-20" version="1">MAYNQSMEEPEFEVNGDEEALRAQAERRRRGTALVLLLIVLLPLVLNLLRWLEGGMGEPVPTRVPTWIPELPVDIHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNV9</accession>
    <name>A0A0N8GNV9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_04900</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061834.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79186">
        <property type="protein sequence ID" value="KPL79186"/>
        <property type="gene ID" value="ADN00_04900"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="338" mass="37204" checksum="41A98428DD735304" modified="2016-01-20" version="1">MTQICIYPPIQGSGGPAAFQARLKTALAEEGVTVHHDPRAACDALLLSGGTRRLDFIWQARRRGVRVVQRLAQLNWVHRVRPSSLGHTLRAERNNWLLAFIRRYLADRVVYQSQFVRQMWADFYGEVSAPGYVIYNATQLDVYRPLPGELPALDRARLLVVEGDLGDTNAVYLENAVRLAQAVQARAQRPVELIVAGKVPDALRQRWTTEAGEMITWAGVVAREDIPALDRSAHLLFSAELNAGCPNSVIEALACGLPVVGYATGALPELVQDGAGELAAYGGNAWRLEPPDTARLADLCLRVLDDQAGYRAAARRRAEALFDARKMARAYLDVLLGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GPD2</accession>
    <name>A0A0N8GPD2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FAD-binding FR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_01625</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061216.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01625"/>
    <dbReference type="EnsemblBacteria" id="KPL80570">
        <property type="protein sequence ID" value="KPL80570"/>
        <property type="gene ID" value="ADN00_01625"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="36"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="2">
        <location>
            <begin position="205"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL80570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="443" mass="49938" checksum="3D77A85248D7A2D9" modified="2016-01-20" version="1">MNTSKTLWIAIYFLSPLLPIGLILAAQPYALNSTPLLLSMVLGASAYTFLSWQFVLSARPPFVEKLFGQDKLYRFHAVMAVVSFVLGFAHRQIKVLVFNRQVLISTIALILLAAVIVASPLFLIDLKPKPVAAIKRFSARVFRLKRRTVKRIHNLTLLISGLLLVHVLDSTSAEQSVAARAVYIAYFAVGMGFYLYHQVLRRWLLKSRAWRVEEVTESAPNIHTIKVAPQRGKRFDYQPGQFAFLRVFSPRIESEEHPFTISSSPTQPGYLTFTVKTSGDYTSQVGQIQPGDAVAVDGPYGVFSYLRHKPQGKIVMIAGGIGVTPLLSMLRYMRDADPNHNVQLIWGVQREDELVYREEVEGLKSTLAQFEWVPVMSNQPDWPGEKGFITRELVEKYAVKAGEDPRAMDFYVCGPPVMMEKVIPMLQGMGVPNSRLHFERFGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WK70</accession>
    <name>A0A0P6WK70_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 9">Heme chaperone HemW</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">ADN00_18705</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Probably acts as a heme chaperone, transferring heme to an unknown acceptor. Binds one molecule of heme per monomer, possibly covalently. Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the anaerobic coproporphyrinogen-III oxidase family. HemW subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064560.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18705"/>
    <dbReference type="EnsemblBacteria" id="KPL70079">
        <property type="protein sequence ID" value="KPL70079"/>
        <property type="gene ID" value="ADN00_18705"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3050"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004109">
        <property type="term" value="F:coproporphyrinogen oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006779">
        <property type="term" value="P:porphyrin-containing compound biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034505">
        <property type="entry name" value="Coproporphyrinogen-III_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010723">
        <property type="entry name" value="HemN_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004559">
        <property type="entry name" value="HemW-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13932">
        <property type="entry name" value="PTHR13932"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06969">
        <property type="entry name" value="HemN_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00562">
        <property type="entry name" value="HemN-like__clustered_with_heat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00539">
        <property type="entry name" value="hemN_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="8 9" id="KW-0143">Chaperone</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 9" id="KW-0349">Heme</keyword>
    <keyword evidence="6 9" id="KW-0408">Iron</keyword>
    <keyword evidence="7 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="10">
        <location>
            <begin position="1"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU364116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL70079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="399" mass="45348" checksum="044FA195CAEEED22" modified="2016-01-20" version="1">MQNYSLYFHIPYCRRRCGYCDFNTTAGMQHTLPFYWQALLKEVRQVAQSAPERLAVHTIFFGGGTPSLVPENDYKRLFVELESLFDFQTPIEITLEANPGTVSPDYLKSLREIGFNRISFGAQSARTQELALLDRDHQFQQVIEAVGMARTAGFENLSLDLIYGLPDQTVDQWLFSLECAAALEPEHLSLYALTVEEGTRMERMVSHGLVNAPEDDTAADMYEAASAWLQRAGYRQYEISNWKLEEKGGRDLACRHNLQYWIFAPYLGFGAGAHGFAAQMRTANVADLEKYIRQVSTSQGTSRFPQGPATLESQELSLQTQMGEFMMVGLRLTEVGVRPAQFRQLFQREIAEVFNAQVRRLLRQGLIEQVDLPDGEHLRLTEKGRLLGNQVFMQFVGED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WQA3</accession>
    <name>A0A0P6WQA3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_15580</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063953.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72237">
        <property type="protein sequence ID" value="KPL72237"/>
        <property type="gene ID" value="ADN00_15580"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="218" mass="25052" checksum="300EEF367DAC4764" modified="2016-01-20" version="1">MSYEQSVDDYSAWFRDAKLALVLSNPDITVFEMKLNINTVMLGFMQNKIVILGCPTTEGNGLVSRPDKGLPWFCSDLPPSELGAAFLKQKWQKDLAVKRWLARAQELIADPTQEVIEWIEFPGRKMTKGEAMEFLYWSKPQVFESCDALHSALPTFWSDYENRVRTSPFDFMSEVCVGIGYSEHMLSWLVGFQKKFAELVKTNHKHLLSQQQKEVESV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WTK7</accession>
    <name>A0A0P6WTK7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">PspC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_14675</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000035">
        <property type="protein sequence ID" value="KPL73581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063782.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000035.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL73581">
        <property type="protein sequence ID" value="KPL73581"/>
        <property type="gene ID" value="ADN00_14675"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007168">
        <property type="entry name" value="Phageshock_PspC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04024">
        <property type="entry name" value="PspC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="33"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="128"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="PspC" evidence="7">
        <location>
            <begin position="3"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL73581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="150" mass="16654" checksum="0E01FEF61A8B77CB" modified="2016-01-20" version="1">MQKRLYRSRKDVILGGVCSGLGDYFGLDPAIFRILFVLFAVAGGPGVLVYIVLWIILPQEGEADSTGAFGGQEFSNRARQMGQEFSQAVRQPNQRGLRYLGIGLLLAGGWLFLQALNLPWLEWANTRLLWPLALVIIGVVMLSRAFRGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WTY9</accession>
    <name>A0A0P6WTY9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">DNA ligase</fullName>
            <ecNumber evidence="10">6.5.1.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Polydeoxyribonucleotide synthase [NAD(+)]</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">ligA</name>
        <name evidence="12" type="ORF">ADN00_19010</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="10">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the NAD-dependent DNA ligase family. LigA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.2" evidence="10"/>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064670.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_19010"/>
    <dbReference type="EnsemblBacteria" id="KPL70175">
        <property type="protein sequence ID" value="KPL70175"/>
        <property type="gene ID" value="ADN00_19010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3114"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003911">
        <property type="term" value="F:DNA ligase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00114">
        <property type="entry name" value="LIGANc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01588">
        <property type="entry name" value="DNA_ligase_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041663">
        <property type="entry name" value="DisA/LigA_HHH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033136">
        <property type="entry name" value="DNA_ligase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001679">
        <property type="entry name" value="DNAligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013839">
        <property type="entry name" value="DNAligase_adenylation"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013840">
        <property type="entry name" value="DNAligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003583">
        <property type="entry name" value="Hlx-hairpin-Hlx_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004150">
        <property type="entry name" value="NAD_DNA_ligase_OB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004149">
        <property type="entry name" value="Znf_DNAligase_C4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00533">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01653">
        <property type="entry name" value="DNA_ligase_aden"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03120">
        <property type="entry name" value="DNA_ligase_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03119">
        <property type="entry name" value="DNA_ligase_ZBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12826">
        <property type="entry name" value="HHH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001604">
        <property type="entry name" value="LigA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00292">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00278">
        <property type="entry name" value="HhH1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00532">
        <property type="entry name" value="LIGANc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="SSF52113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00575">
        <property type="entry name" value="dnlj"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50172">
        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01056">
        <property type="entry name" value="DNA_LIGASE_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 10" id="KW-0227">DNA damage</keyword>
    <keyword evidence="9 10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 10" id="KW-0235">DNA replication</keyword>
    <keyword evidence="2 10 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="7 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="10" id="KW-0464">Manganese</keyword>
    <keyword evidence="4 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 10" id="KW-0520">NAD</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="BRCT" evidence="11">
        <location>
            <begin position="597"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="active site" description="N6-AMP-lysine intermediate" evidence="10">
        <location>
            <position position="117"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="34"/>
            <end position="38"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="83"/>
            <end position="84"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="295"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="319"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="413"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="416"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="431"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="436"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004067"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="HAMAP-Rule" id="MF_01588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KPL70175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="682" mass="74143" checksum="524577E2F2C84AEA" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WVQ1</accession>
    <name>A0A0P6WVQ1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13645</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
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            <taxon>Anaerolineaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="KPL74340">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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            <begin position="72"/>
            <end position="92"/>
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    </feature>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="502" mass="55185" checksum="70D163514F428B11" modified="2016-01-20" version="1">MTQSAGKPEKLIRNQTLVLALLAAACLISAAGYILASRLVYKTGFPLDDAWIHQTFARNLGLYGEWSFLRGIPAAGSTSPLWTFLLAAGYMLGLSPYGWAMALGMCGLFLTAWAGQAFVSEIQVDAPGRWPWVAAFLGFEWHLVWAAVSGMETGVYGGLILVCFYLLARKRKHWLVIGLMAGGMVWVRPDAITLLGPILFVAALEKTSDLPTWKKAAFALAGFSLAFVPYLGFNLSISGSIWPNTFYAKQAEYAVLYQTPLILRFLNLARLPLVGAGVLLLPGFAASAYQSVKQRNFILMSAILWWLGYTGIYAARLPVTYQHGRYLIPAMCVYFVIGAAGMLSLAGLNLPGKWAWGLKTLWKLSFAGVLLVFWGVGANAYGEDVAIIETEMVDTAHWLNENTQPGDLIAVHDIGAIGYFSERSLVDLAGLVSPEVVPYIRDEDGLAVFMDERGVDYLVTFPGWYPRLSEGRMPVYRSDAQFAPNAGGENMAVYRWEIHQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZ37</accession>
    <name>A0A0P6WZ37_9CHLR</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
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            <taxon>Chloroflexi</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
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            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="protein sequence ID" value="KPL72016"/>
        <property type="gene ID" value="ADN00_16110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <location>
            <begin position="12"/>
            <end position="35"/>
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        <location>
            <begin position="47"/>
            <end position="74"/>
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            <begin position="114"/>
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    </feature>
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        <location>
            <begin position="393"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="444" mass="48666" checksum="A11C3F8EB1D18092" modified="2016-01-20" version="1">MIRQFVSGSKKWMTWFAIAAMLASGFLAVFSQWIIAVIEQSGYPAWFSLAFLTGCILLVGVGFTAYEVLVWLCFSLIGFVRIEPAPFDYLLLVVMAIGWARGKLELFNVRQNVLVLSGLWIFILANLVSMVGVAAQPASWRFMLITFYLLVLFLFVRLYGHDEKAIHILLAGYLVSATVNAVLVILGLLGLGFASSMVGWSIRGVGFFKDPNVFGAYMASAAMIAMDRIVHSKGRWYRIVGYGVLTFLLGFTAVYSLSRAVWVSLVLSIGVYAWMLAKEAPRSAVIVLSVLLALAITAVFFLQSSQMAAFVSAHMRLQDYDMARFGNQYQGLIAGLTQPLGVGPAGWPNAHSLYVKTLAEHGLLGLVSLGMVIVGSIWPLIRRVAVMDGSRRALSAQVLLAILIGQLVNSVVIDSIHWRHLWVLLGIAWAFSDGPVTKQGEENG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZ73</accession>
    <name>A0A0P6WZ73_9CHLR</name>
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        <recommendedName>
            <fullName evidence="6">MFS domain-containing protein</fullName>
        </recommendedName>
    </protein>
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        <name evidence="7" type="ORF">ADN00_16485</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
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        </lineage>
    </organism>
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        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72071">
        <property type="protein sequence ID" value="KPL72071"/>
        <property type="gene ID" value="ADN00_16485"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3739"/>
    <dbReference type="Proteomes" id="UP000050417">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
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        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001958">
        <property type="entry name" value="Tet-R_TetA/multi-R_MdtG"/>
    </dbReference>
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        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01035">
        <property type="entry name" value="TCRTETA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
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        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
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        </location>
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        </location>
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        </location>
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            <begin position="333"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="359"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="6"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL72071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="395" mass="42356" checksum="2E299BCF922D9D6E" modified="2016-01-20" version="1">MNMKKPATILSFTLLVVMTGYGMVMPIMPFYIEKLGAGGRELGWLMASYSLMQLICAPAWGMLSDRIGRKPVLTIGVLGYAITLFLFGLADQLWMLFLARSLSGILSSATMPTAMAYIGDHAPKEERSQSMGQLSAAMGIGVVAGPLLGGLLSSDSLALPFFIGAGMAFLAFLLVIFILPESQAPQAPSGRKPRVNRLELRQVFTSPAAILLLPIFIMSFGLTSFQGITGLYVVDRFQFNTQQVGIVWMVMGGVLVLVQGLLTGPLCRRFGELPLIRVGLFGGALGFLFFALAGQFLTILLALGFFSLSLALVGPALNGYISRFAGERQGTVMGMNSAATSLGRIVGPLWAGYLYDLNLVYPFFSGAVSLLLGLLVCLVGIRRQPSNEKNQAVVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZC7</accession>
    <name>A0A0P6WZC7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Multidrug ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ADN00_16185</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064178.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72113">
        <property type="protein sequence ID" value="KPL72113"/>
        <property type="gene ID" value="ADN00_16185"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3674"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="170"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="263"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="30"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="380"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="413"/>
            <end position="420"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL72113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="619" mass="68761" checksum="6F3B165C3FE788FF" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZG1</accession>
    <name>A0A0P6WZG1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_15335</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063913.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15335"/>
    <dbReference type="EnsemblBacteria" id="KPL72199">
        <property type="protein sequence ID" value="KPL72199"/>
        <property type="gene ID" value="ADN00_15335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="213" mass="24497" checksum="E3D11269F1A180CA" modified="2016-01-20" version="1">MKSTRERILQKLLKTPRASINELAEVVGINSISVRHHLSSLQAEGLVTYEEERHGVGRPRLVYFLTEKGMELFPSSYFRFSNRLLEQMKESLPEKTVTKILHEMAKDIAEPYAQKAANLPLEGRLDLVKEILQQEGFSVDWKKRDDQYELTEITCPYYHVSQSHPEVCAIDRTLISSVLQVPIAKIRCVLKGDKTCSYLIDNHQSVKEDSKHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZL7</accession>
    <name>A0A0P6WZL7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AAA_31 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_15825</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72281.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064001.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72281">
        <property type="protein sequence ID" value="KPL72281"/>
        <property type="gene ID" value="ADN00_15825"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_31" evidence="1">
        <location>
            <begin position="3"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72281.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="259" mass="28688" checksum="43735EEA1B143DEB" modified="2016-01-20" version="1">MYCIAIANEKGGVAKTTTTVSLGAALAEAGHRVLVVDLDGQANLTLALGIDPNEQSVSISKVLLSGAPLPAAIQTTVCPRLDILTSNHEMANAERFLPIQKNYEYILRNAIQSLNNLYEYVLYDCPPFLGAATMNALVAADMLLVPTQPEYFSIYALRNLMDWVRMIRSKYNPALTYRLIMTMFDKRNKTHRVLAEQLAENFQSGLLNTFIAMDTKLRESPIAGLPILMHATKSRAAMQYRSLALEITQHAQETTLQPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X138</accession>
    <name>A0A0P6X138_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_11970</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063249.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11970"/>
    <dbReference type="EnsemblBacteria" id="KPL76059">
        <property type="protein sequence ID" value="KPL76059"/>
        <property type="gene ID" value="ADN00_11970"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="247" mass="25649" checksum="0836A26BE2480E83" modified="2016-01-20" version="1">MLITGAAGGIGRATVKVFAEHGWRVIGVDRNAFGEGFPTDGLFIQSDISDPANIEAIFSQAQAFSPVLHAVVNNAGLQFNKPLIETSGEEWDAVMASNLRSVFLGAKLAHPLLKAAGNSAIVNMSSVHAIATSANIAAYAASKGGLLALTRAMAIEFAGDNIRVNAILPGAVDTPMLRASMERGVLDGGSVLSRLENLASKTVNGRIGEPEEIAHAIYFLADSNQSSFMTGQALVVDGGATARLSTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X1A0</accession>
    <name>A0A0P6X1A0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_15045</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000036">
        <property type="protein sequence ID" value="KPL73101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063856.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000036.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15045"/>
    <dbReference type="EnsemblBacteria" id="KPL73101">
        <property type="protein sequence ID" value="KPL73101"/>
        <property type="gene ID" value="ADN00_15045"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1874"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015416">
        <property type="term" value="F:ABC-type phosphonate transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03256">
        <property type="entry name" value="ABC_PhnC_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012693">
        <property type="entry name" value="ABC_transpr_PhnC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02315">
        <property type="entry name" value="ABC_phnC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="35"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL73101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="268" mass="29522" checksum="D53D265EAA718D20" modified="2016-01-20" version="1">MLEIRHLTKVYDDGTVALKDVSFTVQDGEFLVIIGLSGSGKSTLLRCINRLINPTEGEILWDGVDVAKLEGEELRKVRRRIGMVFQHFNLVKRSSVMTNVLSGRLGYAATSSSVFGRFSPADREKARQALTRLGILDQAHKRASELSGGQQQRVGIARALMQDPKMILADEPVASLDPVLAHSILQHLENLNKVDNITVLCSLHYLDLVQRYASRVIGLRAGEIVYEGDKADIMSITDEQFKEIYGQEAERMGAGLEGSLKKSEGGVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X1D5</accession>
    <name>A0A0P6X1D5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L29</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpmC</name>
        <name evidence="6" type="ORF">ADN00_12560</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL29 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063362.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12560"/>
    <dbReference type="EnsemblBacteria" id="KPL76159">
        <property type="protein sequence ID" value="KPL76159"/>
        <property type="gene ID" value="ADN00_12560"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.310">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00374">
        <property type="entry name" value="Ribosomal_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001854">
        <property type="entry name" value="Ribosomal_L29/L35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036049">
        <property type="entry name" value="Ribosomal_L29/L35_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00831">
        <property type="entry name" value="Ribosomal_L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46561">
        <property type="entry name" value="SSF46561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00012">
        <property type="entry name" value="L29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00374"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL76159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="70" mass="8076" checksum="CA42507E2CCD155C" modified="2016-01-20" version="1">MKVKDMRLLSTAELQAKLDDARHELMNLRFQSVTGQLTDTSRLKKTRRLIAQFETILSEQKSAGQREGEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X1P3</accession>
    <name>A0A0P6X1P3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">D-xylose ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_13570</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063562.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000031.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13570"/>
    <dbReference type="EnsemblBacteria" id="KPL74857">
        <property type="protein sequence ID" value="KPL74857"/>
        <property type="gene ID" value="ADN00_13570"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1209"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="67"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="91"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="149"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="186"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="252"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="300"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="380"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL74857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="405" mass="43435" checksum="FBB8392C1B73444B" modified="2016-01-20" version="1">MAVTPEIKKPDEELGLLGELSKRFRQNMQTYTIILALIGIWVFFAVLTKGSFLSAQNFSNLFRQMTVTSFLAIGMVLVIVTAGIDLSVGKAAGFVSVMVAFLQARFWVQTIPIANPIVMAILSVIIGIIIGVIFGALQGSIIAYLRVPPFIVTLGGLFIARGLILWRTEGKTIPANQVGFDYIAQGYLPDLVGWIIAALVVAFLFFSMVTGRKRKRQYGVHVPNFAYDILLTGFFSALVLVYVFMVNQYKGVQVPVALLAVASVLMSYVANNTRFGRYTYAIGGNREAARLSGINIKKTLFMVYTVMGLLVGVGGVVLASYVGYGTIAAGEGYELDAIASAILGGTSPTGGSGTIFGALIGALIMSSLTTGLQMLNVQPYVQYMVKGVVLVLAVLLDVAFKKGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X3G8</accession>
    <name>A0A0P6X3G8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">UDP-glucuronate decarboxylase</fullName>
            <ecNumber evidence="4">4.1.1.35</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_13605</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Nucleotide-sugar biosynthesis; UDP-alpha-D-xylose biosynthesis; UDP-alpha-D-xylose from UDP-alpha-D-glucuronate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the NAD(P)-dependent epimerase/dehydratase family. UDP-glucuronic acid decarboxylase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.35" evidence="4"/>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063572.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000032.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13605"/>
    <dbReference type="EnsemblBacteria" id="KPL74335">
        <property type="protein sequence ID" value="KPL74335"/>
        <property type="gene ID" value="ADN00_13605"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1297"/>
    <dbReference type="UniPathway" id="UPA00796">
        <property type="reaction ID" value="UER00771"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048040">
        <property type="term" value="F:UDP-glucuronate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042732">
        <property type="term" value="P:D-xylose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033320">
        <property type="term" value="P:UDP-D-xylose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044516">
        <property type="entry name" value="UXS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43078">
        <property type="entry name" value="PTHR43078"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="7">
        <location>
            <begin position="4"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL74335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="318" mass="35348" checksum="2770A49DD15C49FD" modified="2016-01-20" version="1">MRVLITGAAGFLGSHLCDRLLKEGHEVIGMDNFITGNAENLGHLSGHPSFSFIRHDVANFIFVPGKIDAVMHFASPASPNPASPFGYTNLPIQTMKAGALGTHNTLGVARAHNARYLLASTSEIYGDPLEHPQKESYWGHCDPIGVRSVYDEAKRFAEALTMAYHRAHGINTRIVRIFNTYGPRMRLDDGRVVPNFIQQALRNEPLTIYGDGAQTRSFCFVEDLVEGIYRLLMSDYHEPVNIGNPVETSILDFAKTIINVLGSQSEITFKMEKRLGDDPQRRRPDISRANQVLAWNPTIALADGIRRTAPYFKSKLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X3U7</accession>
    <name>A0A0P6X3U7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glyceraldehyde-3-phosphate dehydrogenase</fullName>
            <ecNumber evidence="8">1.2.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ADN00_11640</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the glyceraldehyde-3-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.-" evidence="8"/>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063188.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11640"/>
    <dbReference type="EnsemblBacteria" id="KPL76009">
        <property type="protein sequence ID" value="KPL76009"/>
        <property type="gene ID" value="ADN00_11640"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3803"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016620">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020831">
        <property type="entry name" value="GlycerAld/Erythrose_P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020830">
        <property type="entry name" value="GlycerAld_3-P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020829">
        <property type="entry name" value="GlycerAld_3-P_DH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020828">
        <property type="entry name" value="GlycerAld_3-P_DH_NAD(P)-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006424">
        <property type="entry name" value="Glyceraldehyde-3-P_DH_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43148">
        <property type="entry name" value="PTHR43148"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02800">
        <property type="entry name" value="Gp_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00044">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000149">
        <property type="entry name" value="GAP_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00078">
        <property type="entry name" value="G3PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00846">
        <property type="entry name" value="Gp_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01534">
        <property type="entry name" value="GAPDH-I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00071">
        <property type="entry name" value="GAPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Gp_dh_N" evidence="9">
        <location>
            <begin position="3"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glyceraldehyde 3-phosphate binding" evidence="4">
        <location>
            <begin position="160"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Glyceraldehyde 3-phosphate binding" evidence="4">
        <location>
            <begin position="219"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="161"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="12"/>
            <end position="13"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="242"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="324"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="site" description="Activates thiol group during catalysis" evidence="6">
        <location>
            <position position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000149-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL76009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="343" mass="36975" checksum="D93F1D11475A443B" modified="2016-01-20" version="1">MSVKVGINGFGRIGRQVLKAISERYPADLEVVAINDLFDTPTNAHLLKYDTNYGQFPGTVEIDGNDLVVNGKKIKVFAEKDPAALPWKDLGVEIVIESTGVFTNKLASGGKAGAVVHIEAGGAKKVIISAPAKNEDITIVLGVNDDQYDPAKHFVVSNASCTTNCLAPAAKIVHDNWTIKRGMMTTIHSYTNDQRILDLAHKDLRRARAAAMNIIPTTTGAARALALVIPDLKGKFDGYSLRVPTPTVSVVDFVAELEKPTSVEELNAAFKAAAEGPLKGILGFTMEPLVSMDYKGDSRSSIVDGPYTMVMNGTMVKIVTWYDNEWGYSCRTADLAAKMAKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X4I9</accession>
    <name>A0A0P6X4I9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_13320</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74820.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063514.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000031.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13320"/>
    <dbReference type="EnsemblBacteria" id="KPL74820">
        <property type="protein sequence ID" value="KPL74820"/>
        <property type="gene ID" value="ADN00_13320"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13579">
        <property type="entry name" value="Glyco_trans_4_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="16"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="268"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL74820.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="444" mass="50341" checksum="D5345BB2FD98DE6A" modified="2016-01-20" version="1">MKIVISVHHFPPDRIGGAELRAFDMAMWLMQMGHEVRVVTVRNLEKDEQSGIRWSDEEYQGIPVRRLTLVLPSNDKLRFVSLYDNPLIEENLRKYLEAFQPDVFHMVSGYLLGAGAVRAAKSLGIPVTITLTDFWFICPRINMLKSDGSISNKDEFNPETCARCLLAEKRRFQLVYSLFSSPGVSELRQWIEHRLVSQKVVDDLAEQVEQRYITLMGVLDSADSLIFPSRYLLSVCKTRGVTPEKMVYIPHGIHTIGEVQRASLTQPPIRVGYLGQVEHHKGVHLLIEAFLKAASAQDMRLSLFGSSSSNQDYQHKIELLARQDDRIELRGGYSISEIPEILSKLDVVVIPSLWNEIGPLVMFEALRSKVPVIASNIPNMSYEIQDGINGLLFEVGNEDALADILSMLAQHPEKLDGMSRNIQPVRTLEQEMEEIQQIYRQKAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X4N3</accession>
    <name>A0A0P6X4N3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Protein kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_13735</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063629.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000032.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13735"/>
    <dbReference type="EnsemblBacteria" id="KPL74384">
        <property type="protein sequence ID" value="KPL74384"/>
        <property type="gene ID" value="ADN00_13735"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1324"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018391">
        <property type="entry name" value="PQQ_beta_propeller_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002372">
        <property type="entry name" value="PQQ_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011044">
        <property type="entry name" value="Quino_amine_DH_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01011">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13360">
        <property type="entry name" value="PQQ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00564">
        <property type="entry name" value="PQQ"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50969">
        <property type="entry name" value="SSF50969"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="30"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="62"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL74384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="627" mass="70311" checksum="9EC8AEC7244A14D8" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X512</accession>
    <name>A0A0P6X512_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SH3b domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_10020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062863.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10020"/>
    <dbReference type="EnsemblBacteria" id="KPL76924">
        <property type="protein sequence ID" value="KPL76924"/>
        <property type="gene ID" value="ADN00_10020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003646">
        <property type="entry name" value="SH3-like_bac-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08239">
        <property type="entry name" value="SH3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00287">
        <property type="entry name" value="SH3b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51781">
        <property type="entry name" value="SH3B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132845" description="SH3b domain-containing protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="SH3b" evidence="2">
        <location>
            <begin position="74"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL76924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="279" mass="29677" checksum="4AA46F8DB58BB2FC" modified="2016-01-20" version="1">MKKRQMDLLGLVLLVCLSLLCAACAPSQEKMDTLATEVAAGIYATLTAQAPIETPTATIIPSPTAVPSPTTTPTPGAMVAVSVLNVREGPGTTYTALGQLNRGEELDITGQFENCSWVKMKSRSSGLEGWVAGGEQYIELRIPCEQIPLGVFHPQTGWIQRGEGGGYGTMTVDNGTAKDGVVILTANDQAVMAAYIRAGEKFTLQGIQDGTYALYFSTGSDWNGKEFMTDPRRQRFTDAFEFSTSASAYTIWDVTLHTVTGGTASAQDVGEGDFPAIGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5E0</accession>
    <name>A0A0P6X5E0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">TsaA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_10580</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the tRNA methyltransferase O family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10580"/>
    <dbReference type="EnsemblBacteria" id="KPL77079">
        <property type="protein sequence ID" value="KPL77079"/>
        <property type="gene ID" value="ADN00_10580"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd09281">
        <property type="entry name" value="UPF0066"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023370">
        <property type="entry name" value="TrmO-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040372">
        <property type="entry name" value="YaeB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036413">
        <property type="entry name" value="YaeB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036414">
        <property type="entry name" value="YaeB_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12818">
        <property type="entry name" value="PTHR12818"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01980">
        <property type="entry name" value="TrmO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118196">
        <property type="entry name" value="SSF118196"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51668">
        <property type="entry name" value="TSAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="TsaA-like" evidence="3">
        <location>
            <begin position="12"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00033753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL77079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="137" mass="15192" checksum="D14CF7FC1E1137BE" modified="2016-01-20" version="1">MSFWRRALEFTFHEIGHVENTCNELAEPSVIRALQSRIIIHPALTEGLSGFQPGDRLLVLFVFHLIEDGYELMQHPRKDPARAPQGVFTLCSPRRPNPIGATVVDLLEIKGNVLLVAGLDAVNGTPILDIKPAFKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5E6</accession>
    <name>A0A0P6X5E6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Prephenate dehydratase</fullName>
            <ecNumber evidence="3">4.2.1.51</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">ADN00_19045</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H(+) + prephenate = 3-phenylpyruvate + CO2 + H2O</text>
            <dbReference type="Rhea" id="RHEA:21648"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:18005"/>
            <dbReference type="ChEBI" id="CHEBI:29934"/>
            <dbReference type="EC" id="4.2.1.51"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-phenylalanine biosynthesis; phenylpyruvate from prephenate: step 1/1.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.51" evidence="3"/>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70132.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_19045"/>
    <dbReference type="EnsemblBacteria" id="KPL70132">
        <property type="protein sequence ID" value="KPL70132"/>
        <property type="gene ID" value="ADN00_19045"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3122"/>
    <dbReference type="UniPathway" id="UPA00121">
        <property type="reaction ID" value="UER00345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004106">
        <property type="term" value="F:chorismate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004664">
        <property type="term" value="F:prephenate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009094">
        <property type="term" value="P:L-phenylalanine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008242">
        <property type="entry name" value="Chor_mutase/pphenate_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001086">
        <property type="entry name" value="Preph_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018528">
        <property type="entry name" value="Preph_deHydtase_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01842">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00800">
        <property type="entry name" value="PDT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001500">
        <property type="entry name" value="Chor_mut_pdt_Ppr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="SSF55021"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00857">
        <property type="entry name" value="PREPHENATE_DEHYDR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51171">
        <property type="entry name" value="PREPHENATE_DEHYDR_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="6" id="KW-0584">Phenylalanine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Prephenate dehydratase" evidence="9">
        <location>
            <begin position="7"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="ACT" evidence="10">
        <location>
            <begin position="196"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="site" description="Essential for prephenate dehydratase activity" evidence="8">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001500-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL70132.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="284" mass="31445" checksum="E3F7A84779352CA8" modified="2016-01-20" version="1">MKTDLPIIAFQGEHGAFSEAAAFASFGDQITTLPCESFEEVFLAVTSGRADQGLIPIENSQAGSIHQNYDLLLKYNLFITGEHDHKIEHCLIAFPDTERSALTQVISHPQALAQCAGYLSRLPGVKVTAVYDTAGSVKMLKESGDRRMAAIASQRAAELYEMRILDHGIQDSQHNYTRFLRIHPQPVSPQENAKTSLVFSLNHQPGSLYTALSVFARRGINLLKIESRPWVGKMWEYLFYIDFEGAASQPQIAAALAELQEMAPLFRLLGSYPRSKTQLTGASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X6P3</accession>
    <name>A0A0P6X6P3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_05660</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061998.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78728">
        <property type="protein sequence ID" value="KPL78728"/>
        <property type="gene ID" value="ADN00_05660"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="73" mass="8298" checksum="87D3AE23F30E460A" modified="2016-01-20" version="1">MVNTNEHHLVYAILLSGEVNPNRFQDLEPITIELTADGNTRLIKSIKDQAELFGVLNRVRDLGVRLLRVEISQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7N6</accession>
    <name>A0A0P6X7N6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutaredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_18690</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18690"/>
    <dbReference type="EnsemblBacteria" id="KPL70172">
        <property type="protein sequence ID" value="KPL70172"/>
        <property type="gene ID" value="ADN00_18690"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3047"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004362">
        <property type="term" value="F:glutathione-disulfide reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011767">
        <property type="entry name" value="GLR_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011903">
        <property type="entry name" value="Glutaredoxin-like_bact/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13192">
        <property type="entry name" value="Thioredoxin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02187">
        <property type="entry name" value="GlrX_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00195">
        <property type="entry name" value="GLUTAREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin-like_fold" evidence="1">
        <location>
            <begin position="138"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="220" mass="24252" checksum="92F1F9DDE7F6F9D1" modified="2016-01-20" version="1">MLNQDIRKQIKDLFADLKAPVAVLFFGSKVQSCDYCKETVQLLEEVSELSDLIELKQYDLEENAELAKQFSVDKAPVVVLAGKNGDEIVDYGVRFAGIPAGHEFTSLIQGLLMVANSDSGLDDKTKAMLAKVTEPLHFYVFVTPTCPYCPQAVILAHRMAFENPLVQAEMVEAMEFPELSNQFGVSGVPHTVINFGADEVVGAVPEAHMRERLTKLMQSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7U8</accession>
    <name>A0A0P6X7U8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_04370</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061734.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04370"/>
    <dbReference type="EnsemblBacteria" id="KPL79103">
        <property type="protein sequence ID" value="KPL79103"/>
        <property type="gene ID" value="ADN00_04370"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003339">
        <property type="entry name" value="ABC/ECF_trnsptr_transmembrane"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02361">
        <property type="entry name" value="CbiQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="66"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="108"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="137"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="247"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL79103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="286" mass="32659" checksum="6013FA5BDB2ED7DB" modified="2016-01-20" version="1">MNKTLLGYVPNESPIYAVHPFVKLFFLLVVSLFPLFISAPEWNLGLMLAIVLIMWYSRVNMSALRIYVPVAISMGMIILLSYTILGGIHPEFKVMFHVFGFPFYFERIRDAVTVYFRILPMIFTMVLFLSTSRERDVIVAMRAIKVPFVVTYVFAMALRSAGMVLEDFQIVRQAEQARGFDTTGKPLLYKIRKYIMYMIPLFALSLRRSEEFTNALVARGYAFTGEAARVKRADYILTHYTFKPVDIAITATIGLLFVALLVARYGFGMLGLEDSLFNIWLQGLVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7V6</accession>
    <name>A0A0P6X7V6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MFS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_12625</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063444.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000027.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12625"/>
    <dbReference type="EnsemblBacteria" id="KPL75491">
        <property type="protein sequence ID" value="KPL75491"/>
        <property type="gene ID" value="ADN00_12625"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1217"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="83"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="108"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="140"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="176"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="225"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="262"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="291"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="314"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="352"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="376"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="14"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL75491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="405" mass="43903" checksum="289C41BF360B2DF4" modified="2016-01-20" version="1">MDKPADQSFRLYPYRWVVLAVFMFINLTIQVLWIGYAPITGIAAQFYGVTDLQIGFLAMSFMIAFIPLSIPVSWAIDTYGFRLTVSIGAVLMGVFGILRGLAGANYSLVLWSTVGIAAAQPFLLNAWTKVPAQWFSIEERATAVGLVTLANLVGTALGMVLTPILSETISIPNVQLIYGGIAAFSAVLFVLFAREKPATPPCPAGLETRALMLDGLKHALKVKNFWLYLFVSFIGLGIFNGVTTWVENIIRPRGFTPNDAGILGALMLVGGVLGAVIIPPFSDRQHKRQPYILLGFALSIPFLLGITFAADRWLLFACAFAFGFFLVSANPIGMQYAAEITHPTPEGTSNGLIQLFGQASVVFVYIMEMLKTENGAFTPALLLAAALLLISLFLISQMKDCRPAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7W2</accession>
    <name>A0A0P6X7W2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_12685</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75500.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063390.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000027.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12685"/>
    <dbReference type="EnsemblBacteria" id="KPL75500">
        <property type="protein sequence ID" value="KPL75500"/>
        <property type="gene ID" value="ADN00_12685"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1230"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="51"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="75"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="131"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="214"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="238"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="285"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="325"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="363"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL75500.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="391" mass="41395" checksum="8ED38A8F44766A71" modified="2016-01-20" version="1">MSLFQNAQKVLRENIREYGMYIALFVIMAIFTVTTKGVFVSSRNISNLLNQTGYIAVLAVGMTLVIVIRHIDLSVGFLAGFLGAVAAIALVFWKLPTIVVIPLVLALGVVAGMITGFLVAQLKIPSFVASLAGWLIYRGAILLVTAGTGTIIIPDKIFNAIGNGYIPDIKVIPGVHNLTLLLGVAAIILFIVSEISDRQKKQSYNFEVLTMDMFVFKLVFVSALIGAITWILAGYNGLSWTVVVMLVVVAIYHFITTQTVLGRHIYAIGGNPEAAELSGVSVKKLIYVVFGSMGMLSALSGILFSSRLQSATTTAGTLFEMDAIAAAYVGGVSAAGGVGKVTGSIIGALVMTSLTSGMNLMSIDISVQYIVRGAVLAAAVIFDVTTRSRGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7Y5</accession>
    <name>A0A0P6X7Y5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_12910</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063432.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000027.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL75536">
        <property type="protein sequence ID" value="KPL75536"/>
        <property type="gene ID" value="ADN00_12910"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL75536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="144" mass="15875" checksum="695D6990AF20FA98" modified="2016-01-20" version="1">MIESVELSFEIAKLLAHNGYPSDAPAFTVTWGQIAEAVAQTVLAHNLPTGQLTEETVLILADKIQRDLKELDPLNSRGIVLDRVMPPLCSSREVTSREINPALWEPEFEPDEGPLAEMYENATRLGDDEAYWVDAGASAGFDDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X8A0</accession>
    <name>A0A0P6X8A0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_11155</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063092.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11155"/>
    <dbReference type="EnsemblBacteria" id="KPL76520">
        <property type="protein sequence ID" value="KPL76520"/>
        <property type="gene ID" value="ADN00_11155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015969">
        <property type="term" value="P:guanosine tetraphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05399">
        <property type="entry name" value="NT_Rel-Spo_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007685">
        <property type="entry name" value="RelA_SpoT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04607">
        <property type="entry name" value="RelA_SpoT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00954">
        <property type="entry name" value="RelA_SpoT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HDc" evidence="1">
        <location>
            <begin position="49"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="domain" description="RelA_SpoT" evidence="2">
        <location>
            <begin position="247"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL76520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="618" mass="69246" checksum="9C0CDD4B2515CC20" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9H2</accession>
    <name>A0A0P6X9H2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">YcxB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_09800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062821.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76886">
        <property type="protein sequence ID" value="KPL76886"/>
        <property type="gene ID" value="ADN00_09800"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025588">
        <property type="entry name" value="YcxB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14317">
        <property type="entry name" value="YcxB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="184"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="YcxB" evidence="2">
        <location>
            <begin position="101"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL76886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="205" mass="23811" checksum="BBC02011174ACB99" modified="2016-01-20" version="1">MLSFQFVPTKDDYIKAFRAFYLTNWPTWAVIIGVLLFQGLCIASAFIRGDIHFEFSFMVPLMLFAFILFYFAYALIINPLKVANRVEKDKILSSPVQYQATDEGLVIVNQFSENKLTWENFQRVIDSKEVFLLIYSTNKNMFQMIPKRAFSSIEDELAFKNLADQKIPHKKQGFFDSFDSNLKLRLVLVFVVLIFSCAVALFSFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9M2</accession>
    <name>A0A0P6X9M2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PTS EIIB type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_05930</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062047.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05930"/>
    <dbReference type="EnsemblBacteria" id="KPL78771">
        <property type="protein sequence ID" value="KPL78771"/>
        <property type="gene ID" value="ADN00_05930"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1662"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008982">
        <property type="term" value="F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036095">
        <property type="entry name" value="PTS_EIIB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013011">
        <property type="entry name" value="PTS_EIIB_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003501">
        <property type="entry name" value="PTS_EIIB_2/3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02302">
        <property type="entry name" value="PTS_IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52794">
        <property type="entry name" value="SSF52794"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51099">
        <property type="entry name" value="PTS_EIIB_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PTS EIIB type-2" evidence="2">
        <location>
            <begin position="4"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="97" mass="10619" checksum="750BFFFA6F7478D4" modified="2016-01-20" version="1">MKKLRIMTVCGFGLGSSMILKITLDGILKENNIQAETFCADSTTAVGESFDVVFTSRDMSQLFKNVNKPVVVIDNFLSKDEIRSKGLEVVQKAAAES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-08-12" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9R0</accession>
    <name>A0A0P6X9R0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ABC transmembrane type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_06120</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78798">
        <property type="protein sequence ID" value="KPL78798"/>
        <property type="gene ID" value="ADN00_06120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="112"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="266"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="73"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL78798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="298" mass="33883" checksum="C53E08446DF907C2" modified="2016-01-20" version="1">MSGFEMTRFFRTIKPFFYLLPSLVILGLFAYYPAFSVFRLSLFKWEFISPKMEFVGFDQFVRLFGDDRFWNSLWVTAKYTVGVTAVSLFLGLILAVLLNQKKHIPGRSVWRSIYFLPSVTPTVAIAMVWMLIFNPGFGIVNIALRKLGLEGLNWLADMRWALFCVMLLGIWRRMGFNFLNYLAALQNVSESLYESAEIDGANGFEKFLYITLPMVKPTTIMLLILGVIDSFMVIDQILILTGGGPGGSTEVIGQFMYTTAFRLAKLGYGSAISVVMFLIIMIFTVFQWRFVGFGTAEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9V1</accession>
    <name>A0A0P6X9V1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 7">3-dehydroquinate dehydratase</fullName>
            <shortName evidence="7">3-dehydroquinase</shortName>
            <ecNumber evidence="5 7">4.2.1.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Type II DHQase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">aroQ</name>
        <name evidence="11" type="ORF">ADN00_02485</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes a trans-dehydration via an enolate intermediate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>3-dehydroquinate = 3-dehydroshikimate + H2O</text>
            <dbReference type="Rhea" id="RHEA:21096"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16630"/>
            <dbReference type="ChEBI" id="CHEBI:32364"/>
            <dbReference type="EC" id="4.2.1.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 3/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 7">Homododecamer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the type-II 3-dehydroquinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.10" evidence="5 7"/>
    <dbReference type="EMBL" id="LGCL01000011">
        <property type="protein sequence ID" value="KPL79569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061379.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000011.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02485"/>
    <dbReference type="EnsemblBacteria" id="KPL79569">
        <property type="protein sequence ID" value="KPL79569"/>
        <property type="gene ID" value="ADN00_02485"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2807"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00086"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003855">
        <property type="term" value="F:3-dehydroquinate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00466">
        <property type="entry name" value="DHQase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.9100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00169">
        <property type="entry name" value="AroQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001874">
        <property type="entry name" value="DHquinase_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018509">
        <property type="entry name" value="DHquinase_II_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036441">
        <property type="entry name" value="DHquinase_II_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21272">
        <property type="entry name" value="PTHR21272"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01220">
        <property type="entry name" value="DHquinase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001399">
        <property type="entry name" value="DHquinase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52304">
        <property type="entry name" value="SSF52304"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01088">
        <property type="entry name" value="aroQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01029">
        <property type="entry name" value="DEHYDROQUINASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="7 9">
        <location>
            <begin position="104"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7 8">
        <location>
            <position position="26"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7 8">
        <location>
            <position position="103"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7 10">
        <location>
            <position position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001399-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR001399-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR001399-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL79569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="147" mass="15961" checksum="16BBE5377B49C855" modified="2016-01-20" version="1">MSEIITILVLHGPNLNLLGQREPEIYGRTTLEDINSRLTQLAEQRGAKLEIVQSNHEGVLIDALQAAAGRYQGVLINPAAYTHTSVALRDAIAAVGLPAVEVHLSNIHTREEFRHKSLTAAVCVGQICGFGWRSYALGLTALLDLLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9Y2</accession>
    <name>A0A0P6X9Y2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">DNA methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_16710</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the N(4)/N(6)-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064191.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="REBASE" id="132878">
        <property type="entry name" value="M.OapP3M1ORF16710P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL71351">
        <property type="protein sequence ID" value="KPL71351"/>
        <property type="gene ID" value="ADN00_16710"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006306">
        <property type="term" value="P:DNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002941">
        <property type="entry name" value="DNA_methylase_N4/N6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002295">
        <property type="entry name" value="N4/N6-MTase_EcoPI_Mod-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01555">
        <property type="entry name" value="N6_N4_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00506">
        <property type="entry name" value="D21N6MTFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N6_N4_Mtase" evidence="4">
        <location>
            <begin position="22"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL71351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="283" mass="32492" checksum="56A89BF9F696020C" modified="2016-01-20" version="1">MTHTIYFGDNLPILQSLPDESVDLIYIDPPFNTGKTQGRTQIQTVRDETNGDRVGFGGRSYRTVELANRAYRDRFDDFLGFLEPRLIEARRLLAPHGSLYFHIDYREVHYCKILLDEIFGRDAFLNEIIWAYDYGGRTKKKWPPKHDNILYYAKDPENYTFNVDEIERIPYMAPGLVGEEKAARGKLPTDTWWHTIVPTNGKEKTGYPTQKPLGILRRIVQASSRPGDLVMDFFAGSGTLGAACLELNRRFLLIDNNPQAIQVMRQRFTGVSDINWIGLPAED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XB34</accession>
    <name>A0A0P6XB34_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_02810</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000013">
        <property type="protein sequence ID" value="KPL79383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061441.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000013.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02810"/>
    <dbReference type="EnsemblBacteria" id="KPL79383">
        <property type="protein sequence ID" value="KPL79383"/>
        <property type="gene ID" value="ADN00_02810"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003749">
        <property type="entry name" value="ThiS/MoaD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02597">
        <property type="entry name" value="ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="SSF54285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="80" mass="8664" checksum="D97ED0672C537DB6" modified="2016-01-20" version="1">MRLKVKLFASLTRFAPGGQSAGIAFEMDVPEGASLADVAELLRLPAEEIKIAYVNARAQQLDWQLQDDDEIGYFPPVGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XB78</accession>
    <name>A0A0P6XB78_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Aldo/keto reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_10460</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062946.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76990">
        <property type="protein sequence ID" value="KPL76990"/>
        <property type="gene ID" value="ADN00_10460"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2563"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="2">
        <location>
            <begin position="15"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="315"/>
            <end position="330"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL76990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="330" mass="37083" checksum="309C2D4AA251EFBE" modified="2016-01-20" version="1">MEYRFLGKTGVRVSKLCFGAMSFAKDADEAESAALYRRCREAGINFFDCADVYSNGQSEEYLGRFIASERDQVVITSKVYFPSGAGVNDRGSSRYHIVRSVEGSLRRLNTDRIDVYFLHRFDDFTDLEETLRALDDLVRQGKILYPAVSNFAAWQVEKALGISAREGLARLVCLQPMYNLVKRQAEVELLPMAQAEGLGVIAYSPLGGGLLSGKYDQTHRPEDGRLMTNKMYMARYKDDWMYAAAGDLNAFARQNGWEPAALAVAWVMSHPAITAPIIGARNVRQLESSLKSLEIEMTTELRERVSAFTPEPPPATDRNDERDIDFMGKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XB91</accession>
    <name>A0A0P6XB91_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Adenosine deaminase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_10590</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062968.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10590"/>
    <dbReference type="EnsemblBacteria" id="KPL77008">
        <property type="protein sequence ID" value="KPL77008"/>
        <property type="gene ID" value="ADN00_10590"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2589"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019239">
        <property type="term" value="F:deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001365">
        <property type="entry name" value="A_deaminase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006330">
        <property type="entry name" value="Ado/ade_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11409">
        <property type="entry name" value="PTHR11409"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00962">
        <property type="entry name" value="A_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01430">
        <property type="entry name" value="aden_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="A_deaminase" evidence="3">
        <location>
            <begin position="7"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL77008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="334" mass="36640" checksum="D0BA97375E3B3B99" modified="2016-01-20" version="1">MIDLSYPLADLHRHLDGSVRLQTILELGEQHHLPLPAWSVEELRPYVQVTAPQPGVMAFLSKFEWMVGVLADADACRRVAYENVLDAQAEGLDYVELRFSPCFMAEAHNLDPAAVVEAVADGVAAARRDSGMHAKLIGIISRTYGPQKGREELEALLTRREQITALDLAGDEANYPAEWFEEHFRRARDAGWHITVHAGESAGPHSMWTAIDRLGAERLGHAVRAVEDPALMDALAKRGIGIESNLTSNVQTSTVPDYASHPLRQFLERGLAATINTDDPGISGINIAYEYEVAAPAAGLSAEQIHQAQRNALEQAFLSESERAELKARAARRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBG2</accession>
    <name>A0A0P6XBG2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PG_binding_1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_16255</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16255"/>
    <dbReference type="EnsemblBacteria" id="KPL72037">
        <property type="protein sequence ID" value="KPL72037"/>
        <property type="gene ID" value="ADN00_16255"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3688"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.101.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002477">
        <property type="entry name" value="Peptidoglycan-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036365">
        <property type="entry name" value="PGBD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036366">
        <property type="entry name" value="PGBDSf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011044">
        <property type="entry name" value="Quino_amine_DH_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01471">
        <property type="entry name" value="PG_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47090">
        <property type="entry name" value="SSF47090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50969">
        <property type="entry name" value="SSF50969"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="699"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="domain" description="PG_binding_1" evidence="3">
        <location>
            <begin position="792"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="28"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="752"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="28"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="759"/>
            <end position="773"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL72037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="852" mass="91919" checksum="25DB64B2F0EED009" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XCW5</accession>
    <name>A0A0P6XCW5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_14840</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000036">
        <property type="protein sequence ID" value="KPL73067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063815.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000036.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL73067">
        <property type="protein sequence ID" value="KPL73067"/>
        <property type="gene ID" value="ADN00_14840"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL73067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="361" mass="40551" checksum="1D80C04A11214696" modified="2016-01-20" version="1">MRTQTPSGINLHTVKQRLQEAGLPFSQLTLQDGLSIILWQRGGRIFGPFIDEDTPSIGWMSQAFNDPRQFQALIERGEWNVGGTRAWISPELQFHISNRFDFDGSYSLPAALDPGNYSLEQVSSTEFRLSQRIQMDTRILATGTKRLYLEQKIRIAADPLRKLPIYPELKPAYRFGGFEQAFTLVDEDPNPIYSAVWTLMQLQPGGDLLIPTSIPEMVEFYRNPVAEPYLYNHPGYAQVKLTGSHQFKLAYYAAGLTGRLGYIIHTSPQSSTLIVRNYFNNPSAEYAEEPPTRPGINGQSVYVYNDDGALGGFGELECQGQSVGGPNGLRSVSEQMQIWYYTGQRETIGRITQILLGIPIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XCZ0</accession>
    <name>A0A0P6XCZ0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Maltose alpha-D-glucosyltransferase</fullName>
            <ecNumber evidence="3">5.4.99.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Maltose alpha-D-glucosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_15005</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-maltose = alpha,alpha-trehalose</text>
            <dbReference type="Rhea" id="RHEA:15145"/>
            <dbReference type="ChEBI" id="CHEBI:16551"/>
            <dbReference type="ChEBI" id="CHEBI:17306"/>
            <dbReference type="EC" id="5.4.99.16"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyl hydrolase 13 family. TreS subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.16" evidence="3"/>
    <dbReference type="EMBL" id="LGCL01000036">
        <property type="protein sequence ID" value="KPL73094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL73094">
        <property type="protein sequence ID" value="KPL73094"/>
        <property type="gene ID" value="ADN00_15005"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1865"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047471">
        <property type="term" value="F:maltose alpha-D-glucosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032091">
        <property type="entry name" value="Malt_amylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045857">
        <property type="entry name" value="O16G_dom_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012810">
        <property type="entry name" value="TreS/a-amylase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16657">
        <property type="entry name" value="Malt_amylase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02456">
        <property type="entry name" value="treS_nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aamy" evidence="7">
        <location>
            <begin position="17"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001595"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL73094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="542" mass="63218" checksum="2D1FDD5E76DC2E07" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDL1</accession>
    <name>A0A0P6XDL1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Fe-ADH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_00570</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061006.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00570"/>
    <dbReference type="EnsemblBacteria" id="KPL81060">
        <property type="protein sequence ID" value="KPL81060"/>
        <property type="gene ID" value="ADN00_00570"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3509"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001670">
        <property type="entry name" value="ADH_Fe/GldA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018211">
        <property type="entry name" value="ADH_Fe_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039697">
        <property type="entry name" value="Alcohol_dehydrogenase_Fe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023000">
        <property type="entry name" value="Shikimate_kinase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496">
        <property type="entry name" value="PTHR11496"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00465">
        <property type="entry name" value="Fe-ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00913">
        <property type="entry name" value="ADH_IRON_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01128">
        <property type="entry name" value="SHIKIMATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Fe-ADH" evidence="6">
        <location>
            <begin position="8"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL81060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="386" mass="41200" checksum="35774FE1481C22AF" modified="2016-01-20" version="1">MNFSLLTPAKIIFGDGSADQIAPILKSWDSPVLFVTSAYHPSLSYVKELLSTAGVEYYVESVHGEPTMRKIEELTKFAKEHHCGAVLAMGGGSVLDSGKAVSAMINNPGNILDYLEVVGAGKPLQNPTVNMLAVPTTAGTGSEVTKNAVILVEDKHVKVSLRSDWMVPTIALIDPLLTISLPPEITASTGMDALTQVIEPYVSCKANAMTDLFCEAGIQAASQSLLAAYQNGGDLEARRKMAWTSLLGGLSLANAGLGAVHGFAAVLGGMYDAPHGSICARLLPIVFETNAWVLEEAGNQQLFLKRFTQVARWLTGNESATIQDGVNFLGSLADAMSIPYLSEFGVCSEDISEIVEKSRKASSMKGNPIVLKDHVLTEIMVRAMRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDQ5</accession>
    <name>A0A0P6XDQ5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ATPase AAA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_00120</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00120"/>
    <dbReference type="EnsemblBacteria" id="KPL81133">
        <property type="protein sequence ID" value="KPL81133"/>
        <property type="gene ID" value="ADN00_00120"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3420"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011703">
        <property type="entry name" value="ATPase_AAA-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041628">
        <property type="entry name" value="ChlI/MoxR_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07726">
        <property type="entry name" value="AAA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17863">
        <property type="entry name" value="AAA_lid_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_3" evidence="1">
        <location>
            <begin position="38"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="domain" description="AAA_lid_2" evidence="2">
        <location>
            <begin position="230"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF17863"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL81133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="317" mass="35183" checksum="B1F704238D9467FB" modified="2016-01-20" version="1">MSKVQEFSETLKTNLEKVIVGKSETLQLVVIGLLSQGHLLIEDVPGVGKTMLARSLAKSLGCSFRRIQFTPDMLPSDVTGVSIFNQVSRDFEFRPGPLMAQIVLADEINRATPKTQAALLEAMEERQITVDGTTYLLPEPFMVMATQNPIEYEGTFPLPEAQLDRFLMKVKLGYPGLMDEIRVLELQQLKHPIQSLEAMISIEEVLKMQQEIRKVYAAPGIKRYIVEVVRATRESADVYLGSSPRGSLYLFRSSQARAAILGRDFVLPDDVKALAEPVLGHRMVVDPSARLRDISASLIISEVLKSLPVPGGDFSKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDY0</accession>
    <name>A0A0P6XDY0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sulfurtransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_14795</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000036">
        <property type="protein sequence ID" value="KPL73061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063808.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000036.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14795"/>
    <dbReference type="EnsemblBacteria" id="KPL73061">
        <property type="protein sequence ID" value="KPL73061"/>
        <property type="gene ID" value="ADN00_14795"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00207">
        <property type="entry name" value="fer2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042204">
        <property type="entry name" value="2Fe-2S-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036010">
        <property type="entry name" value="2Fe-2S_ferredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001041">
        <property type="entry name" value="2Fe-2S_ferredoxin-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006058">
        <property type="entry name" value="2Fe2S_fd_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007419">
        <property type="entry name" value="BFD-like_2Fe2S-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041854">
        <property type="entry name" value="BFD-like_2Fe2S-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04324">
        <property type="entry name" value="Fer2_BFD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54292">
        <property type="entry name" value="SSF54292"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00197">
        <property type="entry name" value="2FE2S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="489"/>
            <end position="518"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL73061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="697" mass="74644" checksum="3CF52426B2367697" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XF61</accession>
    <name>A0A0P6XF61_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_07380</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07380"/>
    <dbReference type="EnsemblBacteria" id="KPL78279">
        <property type="protein sequence ID" value="KPL78279"/>
        <property type="gene ID" value="ADN00_07380"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001182">
        <property type="entry name" value="FtsW/RodA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30474">
        <property type="entry name" value="PTHR30474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01098">
        <property type="entry name" value="FTSW_RODA_SPOVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0133">Cell shape</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="75"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="136"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="161"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="272"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="304"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="334"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL78279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="401" mass="43158" checksum="246F2D41E609E8A9" modified="2016-01-20" version="1">MHSLRLQMDVPLVLIVASLLVIGLLAVYSSSWEFSLREYEDTSGVFLRQVGFVLLGSGVAVVLSMFDYHLYRKLAVPMMLATIGLLVLVIILNRNNDAEYSRTLFGASVQPSELAKLVAIIYLTVWLASKQAQLNSLSIGLVPMMVILGITAAIIMIQPDFSAAITVVLLGITLFFLAGSDLRQIILLVLIIALMGVLVYFISDTAQERINNFEIGLKTPTEAAYHVKRAFEAVIKGGLFGVGIGRGTTKYMGGLPVPWTDSIFAIVAEETGLIGASVLVLLFLAFIWRGTLIANRAPDLSGKLLAGGVTFWIGFEAILNIAGLLNLAPVAGNALPLISAGGSNMVATLAGIGILFNVARSDHRKQTDTEGRNYRAVVDLRGRNGGRRVSRRGRSAGRISQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XF71</accession>
    <name>A0A0P6XF71_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HTH deoR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_07510</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062363.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78297">
        <property type="protein sequence ID" value="KPL78297"/>
        <property type="gene ID" value="ADN00_07510"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3328"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001034">
        <property type="entry name" value="DeoR_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013196">
        <property type="entry name" value="HTH_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026881">
        <property type="entry name" value="WYL_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08279">
        <property type="entry name" value="HTH_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13280">
        <property type="entry name" value="WYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51000">
        <property type="entry name" value="HTH_DEOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH deoR-type" evidence="3">
        <location>
            <begin position="2"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL78297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="328" mass="36662" checksum="00729D9C278E6424" modified="2016-01-20" version="1">MRADRLLSLLMLLQTRGTTSAAELAVELEVSERTIYRDMLALTTAGVPVYMQRGPGGGCALLDSYRTTLTGLSDPELRALFMLSIPAALRQLGMGSHLEAALQKLLAAQTSQRQQTSVNVRQRVLIDPGSQAHSLSPQPQLYTLHQAVWQEKMVLLRLRLSFGQTAEGRFAPYGMVFDDQNWRLVVEDPRGLMRAVDCEQILEARLLDEPFSRRADFDLHLFWSQWKEKQLAAKPSLQVTLRIVPQWASELPLNFGLPYNQLLRQASPPLPDGSCLLTLSFNDLETARSFVLSLGAAVEVLEPLALRLSVIDFARQTLQVYTSTGLME</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XFI5</accession>
    <name>A0A0P6XFI5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_06730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000018">
        <property type="protein sequence ID" value="KPL78416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062215.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000018.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78416">
        <property type="protein sequence ID" value="KPL78416"/>
        <property type="gene ID" value="ADN00_06730"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025332">
        <property type="entry name" value="DUF4238"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14022">
        <property type="entry name" value="DUF4238"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="132"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="345" mass="40973" checksum="8B2B42EE7BC4CEF9" modified="2016-01-20" version="1">MQQITHNNHFVPQLYLKQWSDDGIHIWSYRILVSHEKVQEWRLLPISGVAYQRDLYTTSVNGNEVDEFEKWLEREFENPVQESINKVLRDEGLATSDWERLATYLGAQDVRTPLSYVEMTERWRKTLPHLMQDTLEKSIKKLEQARNDGEKTRLRSENNEFFNNAFDIQIHRASEIDEKQGYIEVKVVAGRALWLESQKMLLTKTVEALKKHKWSIVYPTQGYQWFTCDHPVVKLNYYGNGNYDLMGGWGNKGTNIIMPLSPRHLLFTQIGDEFPERFTLTPKQTKLFQRFIAERSMRWIFADKPLGIVRKLRPRHIDPEAYSQEIEQWKKWHEEQSKAENNKSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGJ7</accession>
    <name>A0A0P6XGJ7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_06500</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78855.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062150.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06500"/>
    <dbReference type="EnsemblBacteria" id="KPL78855">
        <property type="protein sequence ID" value="KPL78855"/>
        <property type="gene ID" value="ADN00_06500"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043602">
        <property type="entry name" value="CusB_dom_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00529">
        <property type="entry name" value="CusB_dom_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CusB_dom_1" evidence="3">
        <location>
            <begin position="13"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="4">
        <location>
            <begin position="215"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="226"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL78855.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="474" mass="51069" checksum="3CA7874CAD4C9866" modified="2016-01-20" version="1">MKKKTWLIFAGVALVALAAFVFFQFQNSQNSLTANLQLVTVERGDLSAEIGATGTVRANQTAQLVWSTSGIVDEINVELSQSVAADQVLASLSRGSLSQSIILAEADLVNARKSLEDLQNSSTQTAKAKLTLAQAQIAYEDALEDLQSKQFQRASQATLDGLKADLILAENTLDSAEELFEGVADRAEDDPIRATALSQLSNARKAYDRANYNYEYANALPDSDEVEEAQAKVDVAKANLEDAEREWERVKNGVDADEIAAAKARVAAAEATLDMQYIQSPFSGTITAIHNKEGDQVNPNTAAFRIDDLSKLLVDVNLSEIDINQVTIGQSARLTFDAIQGKEYQGEVVEIARVGTTTPNGVEFQVTIELSEIDDAVLPGMTAAVDIITKRIDDVLLVPNRAVRRVDGKQVVYQLIGGEIVPVEIEIGAYEETYSQVISGDIQEGEQIIANPSSDISFTPGSGGRGIIMGAPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XH25</accession>
    <name>A0A0P6XH25_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_02960</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000013">
        <property type="protein sequence ID" value="KPL79400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061464.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000013.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79400">
        <property type="protein sequence ID" value="KPL79400"/>
        <property type="gene ID" value="ADN00_02960"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2227"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00676">
        <property type="entry name" value="UPF0260"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008228">
        <property type="entry name" value="UCP006173"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37421">
        <property type="entry name" value="PTHR37421"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006173">
        <property type="entry name" value="UCP006173"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="153" mass="17591" checksum="9918EBCE644F61EB" modified="2016-01-20" version="1">MLLWSLPVSERFWETKTLEEMTREEWESLCDGCARCCIIKLQDEDSDEVFYTNVVCDLLHLLDCKCTNYQNRSTLVPTCLVLNPQLCRDLDWIPETCAYRLLALGQPLPDWHPLVSGDPESVHKAGISVRGKVVHEKTVDPDKLEDHIGYWVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XIV3</accession>
    <name>A0A0P6XIV3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0261 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_12740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75508.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063400.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000027.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12740"/>
    <dbReference type="EnsemblBacteria" id="KPL75508">
        <property type="protein sequence ID" value="KPL75508"/>
        <property type="gene ID" value="ADN00_12740"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1243"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd15488">
        <property type="entry name" value="Tm-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008322">
        <property type="entry name" value="UPF0261"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044122">
        <property type="entry name" value="UPF0261_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06792">
        <property type="entry name" value="UPF0261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF033271">
        <property type="entry name" value="UCP033271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UPF0261" evidence="1">
        <location>
            <begin position="3"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL75508.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="403" mass="42092" checksum="372E261CC8B0E347" modified="2016-01-20" version="1">MSKTVVMVGSLDTKGEEFAFAKKIIEQAGVKTLVIDFGVMGKPFFEPDVKREDVASAGGGDLAKLASGSHKDDAMKVMTKGLAAVVKKLYAEGKLDGILGMGGSGNTSIATTAMRELPVGVPKLMVSTLGGGDVSAYAGTKDITFMPSVVDVAGINSISRRIYANAAGAIAGMVLAEAGEAGAVKPLITASMFGNTTTCVNAAREIIEKEGYEVLVFHATGTGGKTMESLIADGYIAASLDITTTELADEVCGGVLSAGPERCMAAAKAGIPTVLVPGCVDMANFWGIGTVPEKYKGRNLYEWNPNVTLLRTNVEENITMGKMIARAANASTAPVVVILPLKGVSMLDSEGGRFWDPEADQACFDTIKQNLKPGIPVIEVDNNINDPEFSSKVAQTLLDLLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XJ35</accession>
    <name>A0A0P6XJ35_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_02060</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000008">
        <property type="protein sequence ID" value="KPL79925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061303.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000008.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02060"/>
    <dbReference type="EnsemblBacteria" id="KPL79925">
        <property type="protein sequence ID" value="KPL79925"/>
        <property type="gene ID" value="ADN00_02060"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2842"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="SSF56219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endo/exonuclease/phosphatase" evidence="1">
        <location>
            <begin position="8"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="339" mass="38603" checksum="078AAE4B53D693D2" modified="2016-01-20" version="1">MRLLKITSWNVAHLERLTKPDLSETAQVRRAAVVQELRELNPDVLCLLEGPKGEEGIDLVAQGLLAGDWLPVKAADGEYGQRGAQWIWFLVRRELAPIASLLPVSTWDAFAGEAWPCHFWGSFEAQLHRHYRHPQTLVLDWNGLRVEMVGLHLKSKYVNQGESMWKAGGEKREEFIREALSARIKMTTEAANVRAYIDAKFQQVEKPAIFVMGDLNDGPGKEYFEQRYLFFDLISNVQGDIFAASRFLNHALFDFAGHLRWTVQFDDFVDPDRDPHILLDHILFTQPLVDSSLPWHISAGAGWVEHEIHDLINAPLKEAARSSDHKPVSLRVEVPDLMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKH1</accession>
    <name>A0A0P6XKH1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_12820</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL75520">
        <property type="protein sequence ID" value="KPL75520"/>
        <property type="gene ID" value="ADN00_12820"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL75520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="75" mass="8469" checksum="BB159A07FAD33841" modified="2016-01-20" version="1">MFPFVQSHFIQFAALCFSCTNLAGGFVRKFPSIKDPIEHIANQILFERSGNRYARMTLLAHLDGKAIWKGQLVGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKI5</accession>
    <name>A0A0P6XKI5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_12925</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75539.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063435.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000027.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL75539">
        <property type="protein sequence ID" value="KPL75539"/>
        <property type="gene ID" value="ADN00_12925"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1280"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL75539.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="110" mass="12126" checksum="DDA06788E39BAA81" modified="2016-01-20" version="1">MIVGKITVSTCYGDAIIAVEILGKGPRPGTAWVKALDGLEPFTKMSHGGPYQDDTAVWSTHHLRNVHIENIEAQPVEMQPETEVQPEPAPDWFLEMAYTLCTPRPGGRKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XLF2</accession>
    <name>A0A0P6XLF2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PPM-type phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_00965</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00965"/>
    <dbReference type="EnsemblBacteria" id="KPL81123">
        <property type="protein sequence ID" value="KPL81123"/>
        <property type="gene ID" value="ADN00_00965"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039248">
        <property type="entry name" value="Ptase_RsbX"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35801">
        <property type="entry name" value="PTHR35801"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07228">
        <property type="entry name" value="SpoIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="SSF81606"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL81123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="239" mass="25719" checksum="B746FF584DB95347" modified="2016-01-20" version="1">MEIQIAVAKTKKYGSLESGDTLEIIERPTGGLSAVMADAQLSGKEGKALSSMVVRKVISLLAEGVRDGAASRAASDHLFTERGGGQPVCLNILSADLETNTIVISRNNPTPMFIAQRDRVEVLNAESEAIGASRSVKPTISEIPLEPNTLVVMYTDGLLKAGALTSESVDICTLLESFLEEQDPSPQLIADTILAQAIRLDQNRPSEDMSLVVMRVVPQATDQIRRMCVSMPVLKNQND</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XMQ1</accession>
    <name>A0A0P6XMQ1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">NAD kinase</fullName>
            <ecNumber evidence="5">2.7.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">ATP-dependent NAD kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">nadK</name>
        <name evidence="6" type="ORF">ADN00_08630</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>ATP + NAD(+) = ADP + H(+) + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:18629"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the NAD kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.23" evidence="5"/>
    <dbReference type="EMBL" id="LGCL01000022">
        <property type="protein sequence ID" value="KPL77684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08630"/>
    <dbReference type="EnsemblBacteria" id="KPL77684">
        <property type="protein sequence ID" value="KPL77684"/>
        <property type="gene ID" value="ADN00_08630"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1439"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003951">
        <property type="term" value="F:NAD+ kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019674">
        <property type="term" value="P:NAD metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006741">
        <property type="term" value="P:NADP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.200.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00361">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017438">
        <property type="entry name" value="ATP-NAD_kinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017437">
        <property type="entry name" value="ATP-NAD_kinase_PpnK-typ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016064">
        <property type="entry name" value="NAD/diacylglycerol_kinase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002504">
        <property type="entry name" value="NADK"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01513">
        <property type="entry name" value="NAD_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111331">
        <property type="entry name" value="SSF111331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 5" id="KW-0520">NAD</keyword>
    <keyword evidence="3 5" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="63"/>
            <end position="64"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="68"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="137"/>
            <end position="138"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="202"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="236"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL77684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="286" mass="30987" checksum="E402C960E355DDC3" modified="2016-01-20" version="1">MPQRIAIAWNPDVPDADREAREMESALRAAGLSEVHAASLQDAALHASVGAGAVDLLVALGGDGTMLRAGRLCGPNHVPVLGINMGRFGFLMEVERGQWRDFLSPLLAGHFRLEDRMMLQAEHWRGDTCLNAWTVMNEVVVCRGKDVRPIRLRACVDGYQLATYVADGLIAATPTGSSAYALAAGGPIMPPELRNILIIPVAPHLSVDRAVILSEGVCVTIHVESRYDTVVSVDGQNPEQVLEGDLIKAYAGDHGVSFVRFQDAGYFYRNLTAYMEQNPTSGLPLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XN31</accession>
    <name>A0A0P6XN31_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_08230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062508.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77857">
        <property type="protein sequence ID" value="KPL77857"/>
        <property type="gene ID" value="ADN00_08230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133139" evidence="1">
        <location>
            <begin position="23"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="292" mass="31134" checksum="98EC555BDA4A8364" modified="2016-01-20" version="1">MRNRDRAKKLIKAFFLGAWALAACQPAPLSFTPTVQPAPATPSPVIPTISAPTATLPAPTATAAPSPEPSLEICSPLDGIEISDLPQIISNPFDAPPLGQDDGHHGVDLAFYRFGDRVSMEGLQIHAVLPGKVVGVIANRPPYGYAVVIETAPETIASLLPNLAQAAPALGAVQPHPALNCPEPQQQTYDPARESLYLLYAHMAQPPLVAPGDEIVCGQTLGEVGTTGMSVNLHLHLEARLGPSGYRFASMAHYENAASQDEMANYCLWRVTNTFRMFDPMLLFALQTADAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XNK1</accession>
    <name>A0A0P6XNK1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_09580</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76846">
        <property type="protein sequence ID" value="KPL76846"/>
        <property type="gene ID" value="ADN00_09580"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="68" mass="7593" checksum="A64CA596295C6C22" modified="2016-01-20" version="1" fragment="single">MGNTDQTPFNIDFIQPSQMESSEFHIVFDASENRFHFRGALRSQPLAFLAGEVDSGLSAVFQQAETNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XNY5</accession>
    <name>A0A0P6XNY5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_10295</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76965.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062916.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10295"/>
    <dbReference type="EnsemblBacteria" id="KPL76965">
        <property type="protein sequence ID" value="KPL76965"/>
        <property type="gene ID" value="ADN00_10295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12838">
        <property type="entry name" value="Fer4_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13187">
        <property type="entry name" value="Fer4_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="30"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="71"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="108"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL76965.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="142" mass="15227" checksum="F7BD8F0279E0D365" modified="2016-01-20" version="1">MPTQITEKCTGCTMCVRYCPVDAIRGEKRQQHSVDPHLCIDCNACGRVCAFGAVLDANGQPVEHIKPAQWARPVWDYQTCVACNICVQACPAGVIGQLSANGNGKPRRYPYLANAKACIGCAFCAQACPVSAISMRAPQPEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XPW1</accession>
    <name>A0A0P6XPW1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_09170</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09170"/>
    <dbReference type="EnsemblBacteria" id="KPL77294">
        <property type="protein sequence ID" value="KPL77294"/>
        <property type="gene ID" value="ADN00_09170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="270"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="316"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="365"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="23"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="299"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL77294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="409" mass="44115" checksum="8C44F3D4C828A4FA" modified="2016-01-20" version="1">MRFTMIQLIKMAYRDLGRNRRRSFFSALALGIGLALLLLMAAVMQGEMRSSMDMSIKLQSGHLQVRSINYNPDKNSLAWQDLVENPEQVAAQIATLAPVKAATPRLIASGIVSVSDETAGVTIMGIDPASEASAPYRDSLVGGEYLTADDRGGVLMGKKLADVLGLKVGDTINLMANTSNGDVEEQNFTVRGLYATGSPYYDQTTLLLPLSKAQAITQTENRASHIFVLLTDRDMTEPVVAALQSDQLEVVTWRTMNAMITQIEQMSSGFMVLIYLIVLGITATVIVNTLVMAVFERTREIGILAAIGMRGSRIMAMFFAESTLLAVGGILIGMVLGGIMVAYATYVGFYIGDFGIEGLLIGDRIYAYLTVTDAVSLVITAFVVSLLAALYPALLASRMEPVVALHTGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQ31</accession>
    <name>A0A0P6XQ31_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Fis family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_13710</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063592.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000032.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13710"/>
    <dbReference type="EnsemblBacteria" id="KPL74351">
        <property type="protein sequence ID" value="KPL74351"/>
        <property type="gene ID" value="ADN00_13710"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1319"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="10"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="134"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="134"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL74351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="240" mass="28304" checksum="0F20787C45B58B9C" modified="2016-01-20" version="1">MQESQFQNRLILVVDDEERMARFIRLNLEHDGFQVIEAYRGMDAIQAVRDHMPDLVLLDVMMPDIDGFEVLRLVREVTHVPVIMLTAKGEEDDRVKGLEFGADDYVTKPFSPRELVSRVRAVLRRTELAGSGSKELIEVDDRLKIDFGRREVWVEGEKVQLRPTEYRLLYHLVQNAGWVMTYDQILSKVWGYEYRDESHYVRLYVNYLRQKLEKDPSNPQYILTERGVGYRFVDYRKQAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XR31</accession>
    <name>A0A0P6XR31_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_16265</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064096.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72039">
        <property type="protein sequence ID" value="KPL72039"/>
        <property type="gene ID" value="ADN00_16265"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="67" mass="7558" checksum="9DF721F67509370E" modified="2016-01-20" version="1">MTSSYFSFMIRIWKASAGEPPAWHASLEVPSTHETVYFQSVKDCLDYLRNLEKEDAEGSAENAKETG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XR75</accession>
    <name>A0A0P6XR75_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PfkB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_13485</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the carbohydrate kinase PfkB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13485"/>
    <dbReference type="EnsemblBacteria" id="KPL74845">
        <property type="protein sequence ID" value="KPL74845"/>
        <property type="gene ID" value="ADN00_13485"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01164">
        <property type="entry name" value="FruK_PfkB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017583">
        <property type="entry name" value="Tagatose/fructose_Pkinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000535">
        <property type="entry name" value="1PFK/6PFK/LacC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03168">
        <property type="entry name" value="1-PFK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="3">
        <location>
            <begin position="18"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR000535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL74845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="312" mass="33766" checksum="31A44C42C218C572" modified="2016-01-20" version="1">MILTVTANAALDRVLFIDHFEPTSVMRAERMVDSVGGKGLDASVVLQVLGAPNIAVSFMAGNTGQALAAILDSYGIQHDLVWVHGDTRTANVLIEQDYHRLSHIMTVGYEVNEEEWREFLRKIEQHAPHADWVIMGGSLPKGCPDDLFGQVTHIAHQHGAKCLIDSPGKPMLAALPHKPDILKLNRSEFKATFGLEAAALKDLITPVRELMRVIGVDCVVITAGEDGILLVLPNTAYRAKAPQQVAVNAAGAGDSVSAALTHALTQQMSWEESLRLSAATSAAVVLTEGTADCRMEDIQRLYPLVSVECFNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XS27</accession>
    <name>A0A0P6XS27_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_02535</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000011">
        <property type="protein sequence ID" value="KPL79576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061387.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000011.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02535"/>
    <dbReference type="EnsemblBacteria" id="KPL79576">
        <property type="protein sequence ID" value="KPL79576"/>
        <property type="gene ID" value="ADN00_02535"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023885">
        <property type="entry name" value="4Fe4S-binding_SPASM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034391">
        <property type="entry name" value="Cmo-like_SPASM_containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13186">
        <property type="entry name" value="SPASM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01387">
        <property type="entry name" value="BtrN-like_SPASM_domain_contain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="5">
        <location>
            <begin position="14"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="SPASM" evidence="6">
        <location>
            <begin position="255"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF13186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL79576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="355" mass="39905" checksum="ECBF4AE8E3B70C12" modified="2016-01-20" version="1">MLDQSLRPVKVYFELTNHCNFKCDFCPILVSNRKGHNMDFDLYRKGIDEIVSENITDTVGYHVLGEPLIYSRLAEAIAYAKSKGLHTDINTNGALLTPERVKSLADAGLDEMAISVQLIGEEDHAARGTSISFADYYQRVLNAVKLVRTSGSQMDLILCFMNKSSHKLFDVELAQKMNWESLNRGKLTRYILDVCSVIEKNMSEQQVQQSLRHLNLNRPQMIQLDEHTKIYVHPFGDWGNAFTKKKIHPAHFGTCSYALSNLGVLSNGEITICCPDYDGGTSLGNLNTTSLTEVLTSPRANAIREGFKHNRVVHPRCQHCLGGASLLKTWLKGAISIYLFKVLKFQPAQVKEVRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XSX9</accession>
    <name>A0A0P6XSX9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA-splicing ligase RtcB</fullName>
            <ecNumber evidence="4">6.5.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rtcB</name>
        <name evidence="5" type="ORF">ADN00_11900</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3 4">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="3 4">Binds 2 manganese ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the RtcB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.5.1.-" evidence="4"/>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063237.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11900"/>
    <dbReference type="EnsemblBacteria" id="KPL76052">
        <property type="protein sequence ID" value="KPL76052"/>
        <property type="gene ID" value="ADN00_11900"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3856"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008452">
        <property type="term" value="F:RNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001233">
        <property type="entry name" value="RtcB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036025">
        <property type="entry name" value="RtcB-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11118">
        <property type="entry name" value="PTHR11118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01139">
        <property type="entry name" value="RtcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103365">
        <property type="entry name" value="SSF103365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 5" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 4" id="KW-0464">Manganese</keyword>
    <keyword evidence="3 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="GMP-histidine intermediate" evidence="1">
        <location>
            <position position="406"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="205"/>
            <end position="209"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="237"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="331"/>
            <end position="332"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="331"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="380"/>
            <end position="383"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="387"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="406"/>
            <end position="409"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="482"/>
        </location>
        <ligand>
            <name>GMP</name>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR601233-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU371113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL76052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="483" mass="52600" checksum="DDAC3760F39CDFD8" modified="2016-01-20" version="1">MVMLNDFRKISDFEWELPAGFRDDMRAAVRFFATRSLLEDALGDLSVEQAMNAATLPGVTGHVMVMPDVHQGYGFPIGGVAAMRYQDGVVSPGAIGYDINCGVRLMASRIELEEARPLLDKLAAALDHFCPSGVGTRGERLLKQNELEDVCAQGSRWAKKSGAATEMDLARTEEGGRLAGANPASVSRKAFERAKDQLGTLGSGNHFIEVDVVEDIFDARAAELMGLEPGCLCLLIHCGSRGFGHQICTDYVQDFQSVARRYDLHLPDRELVCAPLESPEGKKYLEAMWCAANYAFANRQLLAHQARKAFESVFAGKVQDWHLFQVYDIAHNMGKEEIHQIEGRETRVCVHRKGATRAFGPGSVDVPDSFRTIGQPVLVPGSMGTASWVLTGTETSMERSLGSCCHGAGRVMSRTKAKHSVRGEDLRRDLLQRGIRVQAGSNAGLAEEAPQAYKDVDEVVKVVSGAGIAQKVARLRPVVVVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XT13</accession>
    <name>A0A0P6XT13_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">50S ribosomal protein L25</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">General stress protein CTC</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rplY</name>
        <name evidence="6" type="synonym">ctc</name>
        <name evidence="8" type="ORF">ADN00_02150</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">This is one of the proteins that binds to the 5S RNA in the ribosome where it forms part of the central protuberance.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the 50S ribosomal subunit; part of the 5S rRNA/L5/L18/L25 subcomplex. Contacts the 5S rRNA. Binds to the 5S rRNA independently of L5 and L18.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the bacterial ribosomal protein bL25 family. CTC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000009">
        <property type="protein sequence ID" value="KPL79787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061318.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000009.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02150"/>
    <dbReference type="EnsemblBacteria" id="KPL79787">
        <property type="protein sequence ID" value="KPL79787"/>
        <property type="gene ID" value="ADN00_02150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008097">
        <property type="term" value="F:5S rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00495">
        <property type="entry name" value="Ribosomal_L25_TL5_CTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.120.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.240.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01334">
        <property type="entry name" value="Ribosomal_L25_CTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020056">
        <property type="entry name" value="Rbsml_L25/Gln-tRNA_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029751">
        <property type="entry name" value="Ribosomal_L25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011035">
        <property type="entry name" value="Ribosomal_L25/Gln-tRNA_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020057">
        <property type="entry name" value="Ribosomal_L25_b-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037121">
        <property type="entry name" value="Ribosomal_L25_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001021">
        <property type="entry name" value="Ribosomal_L25_long"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01386">
        <property type="entry name" value="Ribosomal_L25p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14693">
        <property type="entry name" value="Ribosomal_TL5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50715">
        <property type="entry name" value="SSF50715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00731">
        <property type="entry name" value="bL25_bact_ctc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_TL5_C" evidence="7">
        <location>
            <begin position="99"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01334"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL79787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="211" mass="23231" checksum="181B390EFA383982" modified="2016-01-20" version="1">MEKIVLDATRRSVIGKQVNSLRRDGKLPAVMYGHNFEPTPITLDLHTTSIVLSGVSSSHLITIKLEGKEYATLIREKQRDFIKGTLRHIDFQVVSLTEKIRTSVQVELTGESPAVRLYNGVVVNGITEVEIEALPQDLPDRLTLDLSSLKEIGDGLYVKDLPVSDKVVILTDAEEMVAVITAGAGEEVEAVAVETAEPEVIERGKKEEEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XU37</accession>
    <name>A0A0P6XU37_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH araC/xylS-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_09635</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062791.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09635"/>
    <dbReference type="EnsemblBacteria" id="KPL76856">
        <property type="protein sequence ID" value="KPL76856"/>
        <property type="gene ID" value="ADN00_09635"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2383"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010499">
        <property type="entry name" value="AraC_E-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029442">
        <property type="entry name" value="GyrI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011256">
        <property type="entry name" value="Reg_factor_effector_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06445">
        <property type="entry name" value="GyrI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00871">
        <property type="entry name" value="AraC_E_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55136">
        <property type="entry name" value="SSF55136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="2">
        <location>
            <begin position="12"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL76856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="303" mass="33986" checksum="5B3A3299C78E3823" modified="2016-01-20" version="1">MPTTKEYQERVCRAMNFISRNIERELSLEEIAESAAFSRFHFHRIFKAVVGETVADFTRRLRLELAANRLLSAQFSDITTVALNCGFSSSQNFAKAFRQHFGVTPSQYRKSKIGNIPGKNENAPSLRAVYDVDRLLRDAPRGESRAAMRVDVAAMPALTVAYVRKIGPYIPEVCGAGFAELMRWAAPRNVVGEGTVLAIYWDNPEVTPPDRCRFDACNLVPAGTAPEGQVFIQTIPAGLYALCYFERPPSEIQQAWEDAYLWLCGSGYESSDAPCYERYHNDAAQHPQGKWIFDICIPLKSEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUN2</accession>
    <name>A0A0P6XUN2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Amidohydro-rel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_05795</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="6">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the metallo-dependent hydrolases superfamily. NagA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062022.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05795"/>
    <dbReference type="EnsemblBacteria" id="KPL78876">
        <property type="protein sequence ID" value="KPL78876"/>
        <property type="gene ID" value="ADN00_05795"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1635"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008448">
        <property type="term" value="F:N-acetylglucosamine-6-phosphate deacetylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006044">
        <property type="term" value="P:N-acetylglucosamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00854">
        <property type="entry name" value="NagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003764">
        <property type="entry name" value="GlcNAc_6-P_deAcase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11113:SF14">
        <property type="entry name" value="PTHR11113:SF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038994">
        <property type="entry name" value="NagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00221">
        <property type="entry name" value="nagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="7">
        <location>
            <begin position="81"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="220"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="308"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="4">
        <location>
            <position position="275"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="196"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="217"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="228"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR038994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR038994-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR038994-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR038994-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL78876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="393" mass="42374" checksum="8D8F932F54DA26AE" modified="2016-01-20" version="1">MQAPNLVFKNIHVYEDGQELSHCGLAIEGNSIAYAGEMGGMSISEGAVQVDAAGWWAAPGLVDLQLNGGYGYYFSNDPARVRDVAIRLPEMGVTAFLPTLISEPIDSYPKKIRILQSAREGDGARVLGVHLEGPFLSREKPGAHPPSLLIDPVPEALARLQPLDAVKMVTLAPELPHGMQAIQWFVERGVVVSIGHSQCDLPQLAQAARLGASCATHLFNAMPPLNHREPGMVAAMLTGEEYRLGLIVDGIHVHPEMVKLVWKCRGARGIMLVSDAMGALGMPPGMYQIGEQDVVVDENSARLRDGKLAGSILRMDDAVRNMVEFSGCTRAEAVRMASTTPMEALGLDDRYGHVKTGYQADLVFFDEALRVQLVMIDGKTAFATPGAQARLAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XVM2</accession>
    <name>A0A0P6XVM2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Polyphosphate kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_03230</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the polyphosphate kinase 2 (PPK2) family. Class I subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000014">
        <property type="protein sequence ID" value="KPL79351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061519.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000014.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03230"/>
    <dbReference type="EnsemblBacteria" id="KPL79351">
        <property type="protein sequence ID" value="KPL79351"/>
        <property type="gene ID" value="ADN00_03230"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2057"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008976">
        <property type="term" value="F:polyphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016898">
        <property type="entry name" value="Polyphosphate_phosphotransfera"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022488">
        <property type="entry name" value="PPK2-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022486">
        <property type="entry name" value="PPK2_PA0141"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03976">
        <property type="entry name" value="PPK2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028756">
        <property type="entry name" value="PPK2_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03707">
        <property type="entry name" value="PPK2_P_aer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PPK2" evidence="4">
        <location>
            <begin position="2"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL79351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="256" mass="30218" checksum="2841682CACCCEDC0" modified="2016-01-20" version="1">MSNKEYLEELGKLQLELVKLQEWIKARGLKVVVIFEGRDAAGKGGTIKRITESLNPRVVKVVALGVPTEREKTQWYFQRYVPYLPAAGEMVLFDRSWYNRAGVERVMGFATAEQVQEFFRSCPEFERMLLRSGIILIKYWFSVSDEEQERRFQARIDDPTKRWKLSPMDLKSREFWVEYSKAKDEMFTYTDIKQAPWWVVNADDKKRARLNCIHHLLTQIPYEDLTPPKLELPPRQEDSGYVRPPITDQTFVPEVY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XX00</accession>
    <name>A0A0P6XX00_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_00550</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL81057">
        <property type="protein sequence ID" value="KPL81057"/>
        <property type="gene ID" value="ADN00_00550"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025874">
        <property type="entry name" value="DZR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12773">
        <property type="entry name" value="DZR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00547">
        <property type="entry name" value="ZnF_RBZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RanBP2-type" evidence="4">
        <location>
            <begin position="140"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="domain" description="RanBP2-type" evidence="4">
        <location>
            <begin position="169"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL81057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="197" mass="21337" checksum="5C69DD39F75BA939" modified="2016-01-20" version="1">MEQKIFHGTAKPHDFARALHGKFNRGNLQVQQFGSGDHITVQIATHRYARAGGQTALTISMQQVEDGVSIQIGQQSWLGVAASLGITALAAFHNPISLLQRLDHIAQDLEYVQLTDEVWRVIQETSKRMGLTYQLSNTLRKLVCPYCSVANPVGEPNCIACGAPLGLQQPTTCSRCGFAVRAGASYCPNCGNRITAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XX80</accession>
    <name>A0A0P6XX80_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Acetate kinase</fullName>
            <ecNumber evidence="3">2.7.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Acetokinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">ackA</name>
        <name evidence="5" type="ORF">ADN00_01005</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the formation of acetyl phosphate from acetate and ATP. Can also catalyze the reverse reaction.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>acetate + ATP = acetyl phosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:11352"/>
            <dbReference type="ChEBI" id="CHEBI:22191"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="3">Mg(2+). Can also accept Mn(2+).</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Metabolic intermediate biosynthesis; acetyl-CoA biosynthesis; acetyl-CoA from acetate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the acetokinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.1" evidence="3"/>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061087.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL81131">
        <property type="protein sequence ID" value="KPL81131"/>
        <property type="gene ID" value="ADN00_01005"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3601"/>
    <dbReference type="UniPathway" id="UPA00340">
        <property type="reaction ID" value="UER00458"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008776">
        <property type="term" value="F:acetate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006085">
        <property type="term" value="P:acetyl-CoA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006082">
        <property type="term" value="P:organic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00020">
        <property type="entry name" value="Acetate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004372">
        <property type="entry name" value="Ac/propionate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000890">
        <property type="entry name" value="Aliphatic_acid_kin_short-chain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21060">
        <property type="entry name" value="PTHR21060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00871">
        <property type="entry name" value="Acetate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000722">
        <property type="entry name" value="Acetate_prop_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00471">
        <property type="entry name" value="ACETATEKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00016">
        <property type="entry name" value="ackA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="7"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="281"/>
            <end position="283"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="383"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="3">
        <location>
            <position position="178"/>
        </location>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="3">
        <location>
            <position position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL81131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="403" mass="44211" checksum="55AD00790EF74AFC" modified="2016-01-20" version="1">MNLLVFNCGSSSLNYKVFSGDSNSTAQITAKGKAHRVGVKGSDPSFIEHHLSNQTVKETQPLETHAQAAERVLQNLRDHQIPIDAVGHRFVHGGAYFKESALLTEDTLARLTECLPLAPIHNPNSMSVIYTCLEHQPGCPQYVTFDTAFHAALPPEAYTYAVPQSIRDTHTYRRFGFHGLSYHFVTQAAGPFLETPFSESKIIACHLGTGGSSAVALKNGVPLDTSMGFTPLPGLIMSTRTGDLDAQIPIQLLKEGKSPKEIETLLNKKSGLLGISQFSSDLRDILARVEQDPNAHLAFEMAVHRLVKYIGAYAVLLGGLDALIFTDDIGLWSWQLRESVCQGLTWCGIAIDPTANREAPYDRITPIEAPDSRARVLVIPTDEEWVIGQEGFALLQEGRHAYH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XZ46</accession>
    <name>A0A0P6XZ46_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_00010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000001">
        <property type="protein sequence ID" value="KPL81692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL81692">
        <property type="protein sequence ID" value="KPL81692"/>
        <property type="gene ID" value="ADN00_00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL81692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="195" mass="21571" checksum="A5C2E7F9A5BEDA4B" modified="2016-01-20" version="1" fragment="single">MTEEQKQIEELKQALEARERKLAQAMRVLADRQVEVEKLKAALLGSEGAALSELRADLVPAAASVGQPLDEYARGKGRQLAQAMQTVRNRRLVRILERTVYRKQSQWDLLAPAFQQLKDDTVLYAPTLEGYALRASVNLQFVPLLTYRVELKRAGLKGVLLAFVFDFPPETGELGIELVSAAGQILTQVSVAAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y0C5</accession>
    <name>A0A0P6Y0C5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_05955</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78776.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062053.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05955"/>
    <dbReference type="EnsemblBacteria" id="KPL78776">
        <property type="protein sequence ID" value="KPL78776"/>
        <property type="gene ID" value="ADN00_05955"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="4"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="127"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="127"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL78776.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="230" mass="25907" checksum="C608AAC044B36A45" modified="2016-01-20" version="1">MNETILIVDDEPKIVDLARSYLENGGYRVQAAGDGQTALVLMRTIKPDLVVLDLNLPVMDGLDVCRRLRRESDVPVIMLTARVEETDRLIGLELGADDYITKPFSPRELVARVRALLRRAKGEIRQLNQVRVHDLEIDLEGHTVKKAGAALHLSPNEFKLLAVLAQHPGQTMTREQLMDHLHGVVVSGFDRSIDAHIKNLRKKIEPNPLEPVYILTVYGIGYKFNDEFAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y0Y9</accession>
    <name>A0A0P6Y0Y9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Transcriptional repressor NrdR</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">nrdR</name>
        <name evidence="10" type="ORF">ADN00_13140</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Negatively regulates transcription of bacterial ribonucleotide reductase nrd genes and operons by binding to NrdR-boxes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the NrdR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000030">
        <property type="protein sequence ID" value="KPL75175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063479.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000030.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13140"/>
    <dbReference type="EnsemblBacteria" id="KPL75175">
        <property type="protein sequence ID" value="KPL75175"/>
        <property type="gene ID" value="ADN00_13140"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2878"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00440">
        <property type="entry name" value="NrdR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005144">
        <property type="entry name" value="ATP-cone_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003796">
        <property type="entry name" value="RNR_NrdR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30455">
        <property type="entry name" value="PTHR30455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03477">
        <property type="entry name" value="ATP-cone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00244">
        <property type="entry name" value="TIGR00244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51161">
        <property type="entry name" value="ATP_CONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0678">Repressor</keyword>
    <keyword evidence="6 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 7" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="ATP-cone" evidence="9">
        <location>
            <begin position="48"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL75175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="149" mass="17119" checksum="713BA99009F0B55E" modified="2016-01-20" version="1">MRCPYCQNDKSRVIDTTHDNRGGIRRRRECESCGQRFSSYERPILATPLIVKQDGTREEFNREKLAHGIRISCAKRPVPASQIERLVGEIESALQRMGRAEVSSRVVGDMVINGLKELDQIAYIRYAIVYLQLDDLQAIRKEIDRLLEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y1A1</accession>
    <name>A0A0P6Y1A1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13115</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000029">
        <property type="protein sequence ID" value="KPL75294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL75294">
        <property type="protein sequence ID" value="KPL75294"/>
        <property type="gene ID" value="ADN00_13115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="96"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL75294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="147" mass="16789" checksum="C908DB531306D37F" modified="2016-01-20" version="1">MQHGKEQNHQHGYRHHRQAGNEYFQGIGKTNRRQRGVKRAGKAVQRPHQEHQQVIAESLTHIGHRPAGHRVGGGQLAVVERHAQCQQPAHQQRQHGSRPGDPRRVPGEHKDLSRDGASRSQHDHLQQVELAFQMSFGHRGVDPEWNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y1A6</accession>
    <name>A0A0P6Y1A6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_13000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000028">
        <property type="protein sequence ID" value="KPL75303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063453.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000028.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL75303">
        <property type="protein sequence ID" value="KPL75303"/>
        <property type="gene ID" value="ADN00_13000"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL75303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="194" mass="22601" checksum="C03964CB2167A722" modified="2016-01-20" version="1">MNSEAQIESQENTPSYCAAARGQLSLDELRSCFQINAFQWVILQTLETYDFFRFAEFQIENQLQASLQGDAFSNHGHLRWAREWWVDENGNRQNGWRAVYVGEEAHCPSFLKNSDTVKALKNPQTTTVLLRGERREQQDTWIDLRVPRRLDYPWPETSSVPEKVALEIRQFTIADNRILTQYAQLVSWQEGADS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y1I2</accession>
    <name>A0A0P6Y1I2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4388 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_03310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061540.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03310"/>
    <dbReference type="EnsemblBacteria" id="KPL78941">
        <property type="protein sequence ID" value="KPL78941"/>
        <property type="gene ID" value="ADN00_03310"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025497">
        <property type="entry name" value="DUF4388"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14332">
        <property type="entry name" value="DUF4388"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4388" evidence="1">
        <location>
            <begin position="4"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="271" mass="30729" checksum="780988DE9EE3BC2E" modified="2016-01-20" version="1">MALKGNLRDFTITQLLNLVNLAKKTGTLEIQGSGGAAKVMFREGKLAYAQFSNEDASLASILHRNKKITRSQRQLIANRASQISDKELGLLLINAGYVSQDDILTSLQTYFISVVQRLFTWVEGVFQFEQTLQLPEDKIAVRIDLENLIIEGARQMREWELLQDEIPSLDMALKFTDRPETNLKNVNLSVEEWRVVSYVNPKNSIQQIARAANLSDMEIRKVVYGLLQAGLIEIVRPGGGPTRITKQMFPTTNREEQKNLLSRLVDRIRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y1V4</accession>
    <name>A0A0P6Y1V4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 7">Pyruvate, phosphate dikinase</fullName>
            <ecNumber evidence="4 7">2.7.9.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">ADN00_03535</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + phosphate + pyruvate = AMP + diphosphate + H(+) + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:10756"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.9.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 7 10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the PEP-utilizing enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.9.1" evidence="4 7"/>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061585.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03535"/>
    <dbReference type="EnsemblBacteria" id="KPL78977">
        <property type="protein sequence ID" value="KPL78977"/>
        <property type="gene ID" value="ADN00_03535"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.58"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050242">
        <property type="term" value="F:pyruvate, phosphate dikinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006090">
        <property type="term" value="P:pyruvate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008279">
        <property type="entry name" value="PEP-util_enz_mobile_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018274">
        <property type="entry name" value="PEP_util_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000121">
        <property type="entry name" value="PEP_util_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023151">
        <property type="entry name" value="PEP_util_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036637">
        <property type="entry name" value="Phosphohistidine_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002192">
        <property type="entry name" value="PPDK_AMP/ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010121">
        <property type="entry name" value="Pyruvate_phosphate_dikinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22931">
        <property type="entry name" value="PTHR22931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00391">
        <property type="entry name" value="PEP-utilizers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02896">
        <property type="entry name" value="PEP-utilizers_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01326">
        <property type="entry name" value="PPDK_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000853">
        <property type="entry name" value="PPDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52009">
        <property type="entry name" value="SSF52009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01828">
        <property type="entry name" value="pyru_phos_dikin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00742">
        <property type="entry name" value="PEP_ENZYMES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00370">
        <property type="entry name" value="PEP_ENZYMES_PHOS_SITE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PPDK_N" evidence="12">
        <location>
            <begin position="29"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="PPDK_N" evidence="12">
        <location>
            <begin position="312"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers" evidence="11">
        <location>
            <begin position="436"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilizers_C" evidence="13">
        <location>
            <begin position="565"/>
            <end position="906"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="8">
        <location>
            <position position="470"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="870"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="593"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="649"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9 10">
        <location>
            <position position="783"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="804"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="805"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="806"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9 10">
        <location>
            <position position="807"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000853-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000853-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000853-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KPL78977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="915" mass="100751" checksum="C6C289D69831C06E" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y282</accession>
    <name>A0A0P6Y282_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HTH lacI-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_03895</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061654.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03895"/>
    <dbReference type="EnsemblBacteria" id="KPL79041">
        <property type="protein sequence ID" value="KPL79041"/>
        <property type="gene ID" value="ADN00_03895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="3"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL79041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="338" mass="36731" checksum="B1B3F8EC18217737" modified="2016-01-20" version="1">MSLTLEDIAKISGYSRSTVSRVINGEESVSERAREQVMNVIQNLNFQPNLAARGLAAGRTGVLSLVIPVGVGAIFTDPFFPQLIQNVSSACNALDYTVMLWLAEPEYERRMISKIMYNGLVDGVIVSSMVMDDPIVKALAQGKLPFVLIGRHPNNPKISYIDVDNRVGAREAVLHLIRMGRKRIATITGPQNTIVGYDRYQGYLDALQERGVAVDPNLIIESDFTAAGSYAAALRLIAQRPDAVFAASDPMAISALRAFQEAGFSVPGDLAIIGFDDIPQSAQTNPPLTTVRQPTARMGRIAVETVVDMIHNPSEEPHRIVLPAELVIRSSCGTRMDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y387</accession>
    <name>A0A0P6Y387_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptide methionine sulfoxide reductase MsrA</fullName>
            <shortName evidence="4">Protein-methionine-S-oxide reductase</shortName>
            <ecNumber evidence="4">1.8.4.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Peptide-methionine (S)-S-oxide reductase</fullName>
            <shortName evidence="4">Peptide Met(O) reductase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">msrA</name>
        <name evidence="6" type="ORF">ADN00_02725</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>[thioredoxin]-disulfide + H2O + L-methionine = [thioredoxin]-dithiol + L-methionine (S)-S-oxide</text>
            <dbReference type="Rhea" id="RHEA:19993"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58772"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 4">
            <text>[thioredoxin]-disulfide + H2O + L-methionyl-[protein] = [thioredoxin]-dithiol + L-methionyl-(S)-S-oxide-[protein]</text>
            <dbReference type="Rhea" id="RHEA:14217"/>
            <dbReference type="Rhea" id="RHEA-COMP:10698"/>
            <dbReference type="Rhea" id="RHEA-COMP:10700"/>
            <dbReference type="Rhea" id="RHEA-COMP:12313"/>
            <dbReference type="Rhea" id="RHEA-COMP:12315"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:16044"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:44120"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.8.4.11"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the MsrA Met sulfoxide reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.8.4.11" evidence="4"/>
    <dbReference type="EMBL" id="LGCL01000013">
        <property type="protein sequence ID" value="KPL79371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061426.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000013.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02725"/>
    <dbReference type="EnsemblBacteria" id="KPL79371">
        <property type="protein sequence ID" value="KPL79371"/>
        <property type="gene ID" value="ADN00_02725"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2178"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033744">
        <property type="term" value="F:L-methionine:thioredoxin-disulfide S-oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008113">
        <property type="term" value="F:peptide-methionine (S)-S-oxide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01401">
        <property type="entry name" value="MsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002569">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036509">
        <property type="entry name" value="Met_Sox_Rdtase_MsrA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01625">
        <property type="entry name" value="PMSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55068">
        <property type="entry name" value="SSF55068"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00401">
        <property type="entry name" value="msrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PMSR" evidence="5">
        <location>
            <begin position="10"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001497"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL79371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="182" mass="20630" checksum="F253CF267DCDF9B9" modified="2016-01-20" version="1">MNVQPTLETTTLAGGCFWCLEAVYDQLKGVKDVVSGYAGGSVRNPSYREVCTGRTGHAEVIQIQFDPQEISFRQILEVFFTIHDPTTLNRQGADVGTQYRSAIFYHSPAQKETAEALIRELEAAQLWPDPIITEVTAFDQFYPAEDYHQEYFARNPGQGYCRVVIAPKVAKFRKLYLERLKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y3W0</accession>
    <name>A0A0P6Y3W0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">(Dimethylallyl)adenosine tRNA methylthiotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">ADN00_02315</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000010">
        <property type="protein sequence ID" value="KPL79654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061348.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000010.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02315"/>
    <dbReference type="EnsemblBacteria" id="KPL79654">
        <property type="protein sequence ID" value="KPL79654"/>
        <property type="gene ID" value="ADN00_02315"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2679"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035596">
        <property type="term" value="F:methylthiotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005839">
        <property type="entry name" value="Methylthiotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020612">
        <property type="entry name" value="Methylthiotransferase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013848">
        <property type="entry name" value="Methylthiotransferase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038135">
        <property type="entry name" value="Methylthiotransferase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01938">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00919">
        <property type="entry name" value="UPF0004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01061">
        <property type="entry name" value="methylthiotransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00089">
        <property type="entry name" value="TIGR00089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51449">
        <property type="entry name" value="MTTASE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01278">
        <property type="entry name" value="MTTASE_RADICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MTTase N-terminal" evidence="9">
        <location>
            <begin position="1"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="10">
        <location>
            <begin position="144"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="TRAM" evidence="8">
        <location>
            <begin position="378"/>
            <end position="438"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL79654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="439" mass="49589" checksum="D489E0D7030BB9DD" modified="2016-01-20" version="1">MKYYIWTEGCQMNVSDSQRVSSSLENLGCSLAGRAEEADIIILNTCVVRQSAEDKAYGRLNSLRPLKKKNPRLVINLMGCLVGVKPNQALRERFPFVDVFSPPSNPQPLVEYLIEREGQSLEQRETALRHAAMDGEITLPELERGKLVSAHVPVVLGCSHACAYCIIPYRRGVEESRPPEVILKEARSLVNQGVKEITLLGQIVDRYGKDNPAYPTLAGLIHQLHEIDGLERIRFLTSHPSYMTDELLDCVAELPKVMPHIEVPAQAGDDEVLINMRRGYTNAQYRELISRIREKIPGVSIATDIIVGFPGETEAQFQQTYDLLADLKLDVAHLARYSPRPNTLSARKMEDDVPDEEKWRRFRLLEDLQEGIAAQIHNAYLHQTVPVLVEDRHKARWRGRTPTNKLVFIESDQDLQGQIINATITWTGPWSMQGQLAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y6W4</accession>
    <name>A0A0P6Y6W4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_09365</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062729.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09365"/>
    <dbReference type="EnsemblBacteria" id="KPL77324">
        <property type="protein sequence ID" value="KPL77324"/>
        <property type="gene ID" value="ADN00_09365"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039562">
        <property type="entry name" value="MFP_biotin_lipoyl_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13533">
        <property type="entry name" value="Biotin_lipoyl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Biotin_lipoyl_2" evidence="3">
        <location>
            <begin position="75"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="4">
        <location>
            <begin position="236"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="114"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="230"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL77324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="472" mass="50643" checksum="C3069745C16DAC8B" modified="2016-01-20" version="1">MNLNALKPITWKKGLILGGAAVILLGGAAYLMWGLNASDTAASGQTTYETSPVRSGNLTISASGSGTSVAGQELNLSFSTSGTVSAVHVQTGDQVKEGDLLAELISDESLDVQLLEAKINLENAEQALEDLKTNAQTTLAEAQIAVVEAQEAYEDAKSAVVYEGQARCDEDTTQAYYQEYWEVQQKLDRYTQADYDNSTIYLSEIQPLVQERNSRYATYAYCANFTEYEIAGSQAELTKAEAVLKEAKAALAALEANNGVDPDELALAENKVKSAQMALEKAQANLDGVKIVAPFDGTILSVAGESGDDYESGTFITIGDLNHPNVEFYVDETDMDKVGVGYVANVVFDAFPDTTYSGEVVQVNPYIETSGNSKVLKGLVKITLQNADQSIYLPEGLSAYVDIIGGEATNALLVSVDALHKQDDGSYLVYLLQNGQPVEQPVEIGLMDYTYAEVLSGLSLGQEVVTQIVESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y9I7</accession>
    <name>A0A0P6Y9I7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_06795</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000018">
        <property type="protein sequence ID" value="KPL78439.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062241.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000018.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06795"/>
    <dbReference type="EnsemblBacteria" id="KPL78439">
        <property type="protein sequence ID" value="KPL78439"/>
        <property type="gene ID" value="ADN00_06795"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2272"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="55"/>
            <end position="62"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL78439.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="328" mass="36244" checksum="4D0BE67BD040E47D" modified="2016-01-20" version="1">MIEVQNLTKTYRVPVRQAGLKSALGSLFKPTYEEVPAVRGVSFSVQAGEMVGLIGPNGAGKTTTLKMLAGLLYPSGGSARVADFIPWERKPAYLRRISMVLGNKSQLQWDIPPLDTFRVLGEIYSVPRAEQDQVIDELVELLEMQDLLRKPARNLSLGERMKCELVAGLIHRPQVLFLDEPTLGLDVSMQARLRAFVRRYNQLHGCTVMLTSHYMGDVSALCPRVILIHHGVVLYDGALNGLAQRLSPFKLIQFSLAQTSAEALAAVRLPDGAEWQEGADERQCLRVRREYATETIAALLNALPVADLGVEDPPIEAVIDQIYQEGSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YAG1</accession>
    <name>A0A0P6YAG1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Peptide ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_06385</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062128.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78841">
        <property type="protein sequence ID" value="KPL78841"/>
        <property type="gene ID" value="ADN00_06385"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1780"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025966">
        <property type="entry name" value="OppC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12911">
        <property type="entry name" value="OppC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="35"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="103"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="136"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="272"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="101"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL78841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="307" mass="33367" checksum="0B23FE998473D796" modified="2016-01-20" version="1">MTIVNANSIPRQPGASELSQSYSAQAWRRFKKNKLALFGMAFIIILIAVSIAAPLIAPYDPYKSISNEAGGLDIYAAPSHNFLLGTDSLGRDILSRIIYAGRISLSVGIISILISTSVGIFLGSLAGYFGKWVDSVIMRVVDVVYCFPVLFLIITVSTLLKPSIVNVMIIIGLVSWTNTARLVRGEILRVREYEFVQASRALGARDSSIILQHIIPNILAPILVQATLQTAQAILTEASLSFLGVGVQQPIPSWGNMLYEAMSIMVLRFRPWVWAPPGLAILLTVLSINFVGDGLRDALDPKLKGKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YAR6</accession>
    <name>A0A0P6YAR6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_03600</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061598.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78988">
        <property type="protein sequence ID" value="KPL78988"/>
        <property type="gene ID" value="ADN00_03600"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.72"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="230"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="257"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="287"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="309"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="333"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="364"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="394"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="429"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="509"/>
            <end position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="530" mass="57760" checksum="A181037F80DEC23E" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GKL0</accession>
    <name>A0A0N8GKL0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_18165</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL69994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064466.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18165"/>
    <dbReference type="EnsemblBacteria" id="KPL69994">
        <property type="protein sequence ID" value="KPL69994"/>
        <property type="gene ID" value="ADN00_18165"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2936"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014958">
        <property type="entry name" value="DGC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08859">
        <property type="entry name" value="DGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037181">
        <property type="entry name" value="DGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL69994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="130" mass="13322" checksum="003613966213E793" modified="2016-01-20" version="1">MTECTCSCSCQSTEGPALVFPCSGGSNVGQIANSAAIEMDQQNLARIYCLAGVAAPIPGMVDSAKCASGAIAIDGCPVACAKTALENAGITVSQSIIVTELGITKNHIFEWTAEEVKKVVDAVCLPENLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GL31</accession>
    <name>A0A0N8GL31_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_16780</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064205.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16780"/>
    <dbReference type="EnsemblBacteria" id="KPL71362">
        <property type="protein sequence ID" value="KPL71362"/>
        <property type="gene ID" value="ADN00_16780"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL71362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="186" mass="21922" checksum="8B43BA54CB8D88DE" modified="2016-01-20" version="1">MVPEFLTHYYEASIGPFVSLSDLSDEDAEEVLEMLREEAKVFASRRPEEYLESRWGIETLLRHLFMQKGGQPRRAHPHYMVLGECPWLKSWYPKGRELQIPLSYFPREVISFTYGDTFPAMRTKDGKPYRGRIYMLDELPALIEEFGLPQDWNADGQFGPERYIEAHIWDNAPIVRFMTESQHIVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GLD3</accession>
    <name>A0A0N8GLD3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UPF0102 protein ADN00_15205</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_15205</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the UPF0102 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063889.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15205"/>
    <dbReference type="EnsemblBacteria" id="KPL72178">
        <property type="protein sequence ID" value="KPL72178"/>
        <property type="gene ID" value="ADN00_15205"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00048">
        <property type="entry name" value="UPF0102"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003509">
        <property type="entry name" value="UPF0102"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34039">
        <property type="entry name" value="PTHR34039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02021">
        <property type="entry name" value="UPF0102"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL72178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="121" mass="13942" checksum="DDCED8A857ADE5BE" modified="2016-01-20" version="1">MKRTKQQTGRIGEQLAADFLTRQGFEIAGRNVRTSSGEIDLLARRGDLLVFVEVKTRTSTRFGFPEEAITPKKMARMMACAEEYLQNHAECDQEWRLDVISILAENSRNDPQIEWFENVFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GLE3</accession>
    <name>A0A0N8GLE3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_15690</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72258.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063975.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72258">
        <property type="protein sequence ID" value="KPL72258"/>
        <property type="gene ID" value="ADN00_15690"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72258.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="91" mass="10234" checksum="0A848275B92CA184" modified="2016-01-20" version="1">MATARSKKAPSTQPKPRTIDIEVNVEEFTAGDYEILLDWTTGNSQGHTVGEVFDILDRLVVGGFRHRKLIDLKGVIKTILEKVMEYTDSKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMJ9</accession>
    <name>A0A0N8GMJ9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Proline--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.15</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Prolyl-tRNA synthetase</fullName>
            <shortName evidence="8">ProRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">proS</name>
        <name evidence="10" type="ORF">ADN00_12725</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the attachment of proline to tRNA(Pro) in a two-step reaction: proline is first activated by ATP to form Pro-AMP and then transferred to the acceptor end of tRNA(Pro). As ProRS can inadvertently accommodate and process non-cognate amino acids such as alanine and cysteine, to avoid such errors it has two additional distinct editing activities against alanine. One activity is designated as 'pretransfer' editing and involves the tRNA(Pro)-independent hydrolysis of activated Ala-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Ala-tRNA(Pro). The misacylated Cys-tRNA(Pro) is not edited by ProRS.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-proline + tRNA(Pro) = AMP + diphosphate + L-prolyl-tRNA(Pro)</text>
            <dbReference type="Rhea" id="RHEA:14305"/>
            <dbReference type="Rhea" id="RHEA-COMP:9700"/>
            <dbReference type="Rhea" id="RHEA-COMP:9702"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:60039"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78532"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.15"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2 8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">Consists of three domains: the N-terminal catalytic domain, the editing domain and the C-terminal anticodon-binding domain.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the class-II aminoacyl-tRNA synthetase family. ProS type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.15" evidence="8"/>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75506.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063397.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000027.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12725"/>
    <dbReference type="EnsemblBacteria" id="KPL75506">
        <property type="protein sequence ID" value="KPL75506"/>
        <property type="gene ID" value="ADN00_12725"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1238"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004827">
        <property type="term" value="F:proline-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006433">
        <property type="term" value="P:prolyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00861">
        <property type="entry name" value="ProRS_anticodon_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.800">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.960.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01569">
        <property type="entry name" value="Pro_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002314">
        <property type="entry name" value="aa-tRNA-synt_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004154">
        <property type="entry name" value="Anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036621">
        <property type="entry name" value="Anticodon-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002316">
        <property type="entry name" value="Pro-tRNA-ligase_IIa"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004500">
        <property type="entry name" value="Pro-tRNA-synth_IIa_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023717">
        <property type="entry name" value="Pro-tRNA-Synthase_IIa_type1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044140">
        <property type="entry name" value="ProRS_anticodon_short"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036754">
        <property type="entry name" value="YbaK/aa-tRNA-synt-asso_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007214">
        <property type="entry name" value="YbaK/aa-tRNA-synth-assoc-dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03129">
        <property type="entry name" value="HGTP_anticodon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00587">
        <property type="entry name" value="tRNA-synt_2b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04073">
        <property type="entry name" value="tRNA_edit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01046">
        <property type="entry name" value="TRNASYNTHPRO"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55826">
        <property type="entry name" value="SSF55826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00409">
        <property type="entry name" value="proS_fam_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="9">
        <location>
            <begin position="46"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL75506.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="583" mass="64338" checksum="30478E91A99B7CF8" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMT2</accession>
    <name>A0A0N8GMT2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_11780</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76170">
        <property type="protein sequence ID" value="KPL76170"/>
        <property type="gene ID" value="ADN00_11780"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1420.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004481">
        <property type="entry name" value="K/Na/Ca-exchanger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004837">
        <property type="entry name" value="NaCa_Exmemb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044880">
        <property type="entry name" value="NCX_ion-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10846">
        <property type="entry name" value="PTHR10846"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01699">
        <property type="entry name" value="Na_Ca_ex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="79"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="103"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="128"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="176"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="210"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="248"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="275"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="308"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="domain" description="Na_Ca_ex" evidence="6">
        <location>
            <begin position="3"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="domain" description="Na_Ca_ex" evidence="6">
        <location>
            <begin position="182"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL76170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="327" mass="35436" checksum="B9C6196680B0715D" modified="2016-01-20" version="1">MGALVLLVVTANVAVKKLIGIASFFHLSSTFMGMTVVSLATSIPEITAHLTASTNILRGTLDYEVGSAIVLGANIGSDVVQQTFILGLVVFIAGGLTFRRYFLWKSMIPMILTNVLCIFLALNGNFSRLDGIILLISFMVYNYFLYMDERKFYRKEDNLHQDEEIANSVPRNLKEVLIDTLVALGMIIITIFSATYVLNITEMIVNRTGIGGSLIGVVTLGVASALPELTTALAGIGKKEHGISLGTLIGSNITNPLVAIGGGALLSTYAAPRPLILWDLPAATFTGAVLWAVIWFSKGKLSKWGATYLLVLYFIYILIRALFFAVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMX3</accession>
    <name>A0A0N8GMX3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_11030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063067.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11030"/>
    <dbReference type="EnsemblBacteria" id="KPL76498">
        <property type="protein sequence ID" value="KPL76498"/>
        <property type="gene ID" value="ADN00_11030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006603">
        <property type="entry name" value="DinF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00797">
        <property type="entry name" value="matE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="165"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="197"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="286"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="321"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="356"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="392"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="467" mass="51198" checksum="CB263AED2583014F" modified="2016-01-20" version="1">MFKNLFNDPKFYKTLFQLALPITVQYFISSSISLVGVMMVGQLGEVSIAALGLGNQIFFLVSLLIFGLSSGYAIFAAQFWGANDLPNVRRVLGICLTLGMIAAGIFTLAAVLLPHPILSIYTKDPEVIREGVQYLRIAAFSYVPYALSMAFAFMHRSTGQVRLPMFVSAISLLLSVLVSYLLIFGHLGLPALGVRGAAVGMLFARLVEAAGMLSLTYLKRTAIAASPKELFSFNLPFLTQTLSTAMPAVLNEMAWSFAVTTYNIVYARIGTESIAAINITTTIEEMAFVVFFGLANAGAIIIGNTIGAGEQEKAFTYGKRYILIGIAGALVFGQLTSLSSRWILNFYNISPTAADYVRNILLIFSFIMWIKVFNLMLIVGILRSGGDTRFTLLLEMSAIWGIGVPMAVLGGLVLHLEVYWVYLMVISEELVKAFFGYRRFRSRKWVHNLTVVSQVVEPLPAAPSQVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMY1</accession>
    <name>A0A0N8GMY1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ABC transmembrane type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_11435</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76562.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063146.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11435"/>
    <dbReference type="EnsemblBacteria" id="KPL76562">
        <property type="protein sequence ID" value="KPL76562"/>
        <property type="gene ID" value="ADN00_11435"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.987"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="64"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="100"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="133"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="178"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="232"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="65"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL76562.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="271" mass="30549" checksum="ADD6BB1D3D9B2F59" modified="2016-01-20" version="1">MNQRKLAFSIGWGYYLVITLLLYIPIVLLIVFSFNDSTLLAFPLKGFTLKWYQQLWEDTELLRALYNSLVVGILSSLVATAIGTFAAIGVTRFHFIGKDFFLTVASLPLVVPYVVLGVAMLLLFRFLGIELSLWTVGIGHVVINIPYVLLIVAARLAGFDKRIEEAAMDLGANYWQTLWRVTLPICMPALLASFLSSLTTSFDEFALTFFLTGTDNTLPIYLYSQLRFPTRVPLVITLAAVIILVTLVIVLLQEWLRHLDQPKRRKGIEIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GN26</accession>
    <name>A0A0N8GN26_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062861.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10010"/>
    <dbReference type="EnsemblBacteria" id="KPL76922">
        <property type="protein sequence ID" value="KPL76922"/>
        <property type="gene ID" value="ADN00_10010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="SNARE_assoc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="SNARE_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="134"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="194" mass="21733" checksum="5312545935712893" modified="2016-01-20" version="1">MNSLANWTVTHLAAYGVPLLLLVAFAGSLGIPFPITMVIIAAGAFAHEGLLDWRLAGLACLAGASLADHFEYFLGRWAGERLRLRLEKRAAWQRAQSVINRQGAWAILLTRFWFTPLAPAVNFIAGSRYPYLRFLLYDVAGQLLWVFIYGGLGYLFAEQWQRVSETVGSFTSLSMVVLLLAALLFILWPRRARE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNJ9</accession>
    <name>A0A0N8GNJ9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_07575</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062374.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78306">
        <property type="protein sequence ID" value="KPL78306"/>
        <property type="gene ID" value="ADN00_07575"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3342"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="235"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="265"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="301"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="355"/>
            <end position="374"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="399" mass="43466" checksum="830E19F3AAEE5162" modified="2016-01-20" version="1">MRNIWLVFWHEYARQVLRKRFLLVLLSLPLIIVLSGGVGVLAVVVMMNNDPIGYVDHSGLLTNPAAPAQTAERRVDMIAFADDASAQQALEEGQIQGYYVVAKDYLQTGEVVLVAEEPVGENAQDDFVDFLKVNLVKGLDSAVAERLMDGSKIEVRALEDLTRKAGENDWVNLVIPLVMGIFLMLAVNTSGGYLLQAVVEEKENRTMEIVITSISPEQLMAGKILGNLSVGLTQLLVWFAVPVGVFLGVRPFVPFLRDINLGGSYVWLSLAALPAAFVLVAALMAAVGATATEAREAQQMAGLFTIPLFVPYWLITPLIESPNSLLAVGLSLFPLTAPVTLAARAAFTVLPVWQIVVSLGLLYATAFGALWLAGRAFRLGMLQYGKRLKLAEIFRRQEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNR4</accession>
    <name>A0A0N8GNR4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_06300</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062113.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06300"/>
    <dbReference type="EnsemblBacteria" id="KPL78826">
        <property type="protein sequence ID" value="KPL78826"/>
        <property type="gene ID" value="ADN00_06300"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="281"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="309"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="338"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL78826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="361" mass="39968" checksum="BA259D02500E866C" modified="2016-01-20" version="1">MNTTIPTSFSTDSVYRRLARVLDELPNRFPAAEDESDLRLLAKLFSEPEAELAAQLSLDLETPAQIAGRLGRDMRETAGLLKEMSRKGLITIGKTKEGRLGFGLMPFVVGIYEAQVNRMDAEMAELYEAYYQSAFHRALLEQPQVHRVIPVGESVKNNMEVRPFESASEIVNMAQSWGVVDCICRTQKALIGKPCGHPLDVCMILSTQPNAFDNNVTGIRMQTQEEALQTLQRAAQAGLVHCVSNHQRELWYICNCCTCSCGVLRGMAEMGIANVVARSAFVNQVDESLCVGCGECMQACQFSALTLEDVIRVDAMRCVGCGLCVPVCPQDALSLVRRPGEEDPPPTEEDWRQVRRSAHLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNS1</accession>
    <name>A0A0N8GNS1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AAA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_06145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78882.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06145"/>
    <dbReference type="REBASE" id="132868">
        <property type="entry name" value="OapP3M1McrBCP"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78882">
        <property type="protein sequence ID" value="KPL78882"/>
        <property type="gene ID" value="ADN00_06145"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1708"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011704">
        <property type="entry name" value="ATPase_dyneun-rel_AAA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07728">
        <property type="entry name" value="AAA_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="206"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78882.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="472" mass="54802" checksum="9C80AE58437519C1" modified="2016-01-20" version="1">MERENINYWLVGAYWSDSNPKDQTERFIAEGIWKNGHENKYLDDVKSMKVGDKIAIKATTTQRSGLPFDSRNKTVSLMIIKAVGTVVANRNDGRTVEVEWDTDFKEKNWYFYTVWNTVWHLKRTQKNDKLQTVEKLIDFIWYGKDQDYDWFIKNWLDIESSDKTEEINGTSDIIFGKTPYSVEDIIASGVFLEITEINQILSRLKEKKAIIIQGPPGVGKTFIARKLAYALMSEIDNNRLEFVQFHQSYSYDDFVRGYRPLPDKAGAFGIKDGIFIRFCQKAIGDPDREYVFIIDEINRGNLSQIFGELLMLIEHDKRGADFSVPLVYTQEGEPRFYIPSNVFIIGLMNLADRSLAMVDYALRRRFAFITLSPRFESKQFENWLSARSMATELIKHIVSRISAINNEIRADPLLGENYQIGHSYFCPKGDDFSELDVSWYVSIVKTEIVPLIKEYWFDNPKKAENGERILLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GP07</accession>
    <name>A0A0N8GP07_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_02495</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000011">
        <property type="protein sequence ID" value="KPL79570.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061381.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000011.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79570">
        <property type="protein sequence ID" value="KPL79570"/>
        <property type="gene ID" value="ADN00_02495"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2809"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="178"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="118"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79570.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="204" mass="21778" checksum="6D3B60FC868BFD62" modified="2016-01-20" version="1">MSKPKLRAIIIFITLLGVSLSSLFITGKIIAAPPAQSDTPVHGWNVCEDLGMGAIPGLGDTRQRFRLCNSGWEILTYCLDPGEAPPTVGAMCSRVSEDVYWCSDAAQQIRFYEMVQTPAPEQPPAPTHTPTPTVTSTPTPTNTTQPPSPPQESEEEEEEAAPTAQPAPRPQPGGPGNLGYLLAAGFTVLGGGGFTFYRLAIKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GP66</accession>
    <name>A0A0N8GP66_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA threonylcarbamoyladenosine biosynthesis protein TsaE</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaE</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_01870</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TsaE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000007">
        <property type="protein sequence ID" value="KPL80042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01870"/>
    <dbReference type="EnsemblBacteria" id="KPL80042">
        <property type="protein sequence ID" value="KPL80042"/>
        <property type="gene ID" value="ADN00_01870"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2300"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003442">
        <property type="entry name" value="T6A_TsaE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02367">
        <property type="entry name" value="TsaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00150">
        <property type="entry name" value="T6A_YjeE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00032441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL80042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="172" mass="19131" checksum="3DD2EDCF706FB02E" modified="2016-01-20" version="1">MWVPYNFNMPILSPNALEFFSRSPEQTRRLGARLGALLSAGDVVCLSGDLGSGKTTFVKGIAQGWGSLDAVTSPTFVLVNYYSRPQGETLYHLDAYRLEGAEEAEALDMDWMLDSGALVVEWPERIKSALPADCLWVHLSYIDDLQRGMVFKAEGNRYNTLLADFRRQAFGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GPC6</accession>
    <name>A0A0N8GPC6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Large-conductance mechanosensitive channel</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">mscL</name>
        <name evidence="11" type="ORF">ADN00_01350</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Channel that opens in response to stretch forces in the membrane lipid bilayer. May participate in the regulation of osmotic pressure changes within the cell.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homopentamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the MscL family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80522.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061165.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01350"/>
    <dbReference type="EnsemblBacteria" id="KPL80522">
        <property type="protein sequence ID" value="KPL80522"/>
        <property type="gene ID" value="ADN00_01350"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1021"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008381">
        <property type="term" value="F:mechanosensitive ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00115">
        <property type="entry name" value="MscL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019823">
        <property type="entry name" value="Mechanosensitive_channel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001185">
        <property type="entry name" value="MS_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037673">
        <property type="entry name" value="MSC/AndL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036019">
        <property type="entry name" value="MscL_channel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30266">
        <property type="entry name" value="PTHR30266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01741">
        <property type="entry name" value="MscL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01264">
        <property type="entry name" value="MECHCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81330">
        <property type="entry name" value="SSF81330"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00220">
        <property type="entry name" value="mscL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01327">
        <property type="entry name" value="MSCL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 10" id="KW-0407">Ion channel</keyword>
    <keyword evidence="7 10" id="KW-0406">Ion transport</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 10" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL80522.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="151" mass="15936" checksum="71932E83D684B33A" modified="2016-01-20" version="1">MWAELKKFLLRGNVVDLAVGVIIGGAFGGIVNSLVNDVIMPPVGLLLGKVDFKDLYLLLKSGEPAAPYATLADAQEAGAVTLNYGVFLNSVISFLIVGLAVFLLVRAVNHLVEKEEPAAPAEPSEKTCPFCATAIPVEAVRCPHCTSDLSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WML5</accession>
    <name>A0A0P6WML5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PKS_ER domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_18320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064496.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18320"/>
    <dbReference type="EnsemblBacteria" id="KPL70021">
        <property type="protein sequence ID" value="KPL70021"/>
        <property type="gene ID" value="ADN00_18320"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004104">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020843">
        <property type="entry name" value="PKS_ER"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00829">
        <property type="entry name" value="PKS_ER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKS_ER" evidence="1">
        <location>
            <begin position="40"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="719" mass="77282" checksum="03E5287FC0B0ED18" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WQ29</accession>
    <name>A0A0P6WQ29_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pilus assembly protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_15275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063903.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72191">
        <property type="protein sequence ID" value="KPL72191"/>
        <property type="gene ID" value="ADN00_15275"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.757"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007047">
        <property type="entry name" value="Flp_Fap"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04964">
        <property type="entry name" value="Flp_Fap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="48" mass="5047" checksum="5C65338A4EF89652" modified="2016-01-20" version="1">MLFAPKEKGQGLVEYALILVLVAVVVIVILALLGPAIGRIFSNVVEAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WVR0</accession>
    <name>A0A0P6WVR0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Polysacc_synt_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_18335</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064499.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18335"/>
    <dbReference type="EnsemblBacteria" id="KPL70023">
        <property type="protein sequence ID" value="KPL70023"/>
        <property type="gene ID" value="ADN00_18335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029303">
        <property type="entry name" value="Polysacc_synt_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14667">
        <property type="entry name" value="Polysacc_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="48"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="121"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="151"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="175"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="228"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="269"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="298"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="341"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="370"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="395"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="domain" description="Polysacc_synt_C" evidence="7">
        <location>
            <begin position="342"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL70023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="431" mass="48105" checksum="BF70DB9391109C3E" modified="2016-01-20" version="1">MSDQDFKHVVNLLKKLGLSIGDQGLYSATNFLLNILMVRWLSIEEYGFFALSFSLFLFFSSIHNSVILEPITVLATANHKDHLGDYLRTETRLNLYTVTAIGIVCIVSSFVAGIFSSRMGTSLMVVGLSTPFLLSYWFFRRICYIENLPHVAVFGSGVYSVLVLTGIFLMRNSNFLGSIAAFALMSLASLISSLVIWVGFRRLRTDRPEEKSAAIHEVMKEQWHYGKWVIGVSILYWINSSISIPFLALDTGFGESGVYRSLQNLILPLQQIGVAIGNLFLPWFAAIRFSNRKQANRLILQVIAGFFVSGIIFILPILIFPEVVLSALYGTGNFESYLLEARVISIVGLVLMINAVLTFILQARKKPNSVLFANLCGSIISIFLVIPIIQQLGLFGAVIGLLMTSIAILIPLLILVKNQFQHYENYMVSNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WVS5</accession>
    <name>A0A0P6WVS5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Hydrolase_4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_13830</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063612.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000032.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13830"/>
    <dbReference type="EnsemblBacteria" id="KPL74367">
        <property type="protein sequence ID" value="KPL74367"/>
        <property type="gene ID" value="ADN00_13830"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012354">
        <property type="entry name" value="Esterase_lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017388">
        <property type="entry name" value="Esterase_lipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydrolase_4" evidence="3">
        <location>
            <begin position="22"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="1">
        <location>
            <position position="203"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="1">
        <location>
            <position position="233"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="28"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR017388-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR017388-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL74367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="263" mass="28988" checksum="AEEE30A823FE8E2B" modified="2016-01-20" version="1">MPSSYPVPQTQPFLLPGGSTGVILVHGFTSTPKEMSRLGAYLNQQGFTVIAPRLPGHALTIQDMPRTRYQDWYNALEDAYQLLRPHCAQMAIVGVSMGGALSLLFAANHPFDALVTLSAPYDLADSPRLRKILPLLRLLSRVKPFLKKPKGGHWFNPEAGREHYSYRYNPTRSAVELLLMLSEMQAALPRVTAPALLIHSLDDGYVHPANLLPLFALLGSPQKDMRFIQGSSHCVTIDGDRQALYEQIGAFLTARCASTPPAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WY30</accession>
    <name>A0A0P6WY30_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6">GTPase Era</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">era</name>
        <name evidence="12" type="ORF">ADN00_14755</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 8 9">Belongs to the TRAFAC class TrmE-Era-EngA-EngB-Septin-like GTPase superfamily. Era GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000035">
        <property type="protein sequence ID" value="KPL73596.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063797.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000035.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14755"/>
    <dbReference type="EnsemblBacteria" id="KPL73596">
        <property type="protein sequence ID" value="KPL73596"/>
        <property type="gene ID" value="ADN00_14755"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2117"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070181">
        <property type="term" value="F:small ribosomal subunit rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042274">
        <property type="term" value="P:ribosomal small subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04163">
        <property type="entry name" value="Era"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00367">
        <property type="entry name" value="GTPase_Era"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030388">
        <property type="entry name" value="G_ERA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005662">
        <property type="entry name" value="GTP-bd_Era"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004044">
        <property type="entry name" value="KH_dom_type_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009019">
        <property type="entry name" value="KH_sf_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42698">
        <property type="entry name" value="PTHR42698"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07650">
        <property type="entry name" value="KH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54814">
        <property type="entry name" value="SSF54814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00436">
        <property type="entry name" value="era"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51713">
        <property type="entry name" value="G_ERA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50823">
        <property type="entry name" value="KH_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6 8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="4 6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Era-type G" evidence="11">
        <location>
            <begin position="8"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="domain" description="KH type-2" evidence="10">
        <location>
            <begin position="208"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="region of interest" description="G1" evidence="8">
        <location>
            <begin position="16"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="G2" evidence="8">
        <location>
            <begin position="42"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="G3" evidence="8">
        <location>
            <begin position="63"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="G4" evidence="8">
        <location>
            <begin position="127"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="G5" evidence="8">
        <location>
            <begin position="156"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="16"/>
            <end position="23"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="63"/>
            <end position="67"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="127"/>
            <end position="130"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KPL73596.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="305" mass="33872" checksum="24E403F835E2AFF2" modified="2016-01-20" version="1">MTSESVFHSGYVTLIGRPNVGKSTLLNAILKQKVAAVSPRPQTTRKRQLGILTDDSAQIIFIDTPGIHKPHHKLGEFMNESATDTLLDADLILWVVDASEAPHEEDFLIANRLNAIRADLPVILALNKVDTLNAEQIAERREKFTALYPNARPIEISALTGAGQSSLMDLLISSLPAGPKYFPEDTVTDLYERDIAADLIREAALVHLRDEIPHAMAVRIDEYLERGETGAKISATLFVERDSQKGIVIGKGGSMLKEIGSTARKEIERMSGRKVFLDLRVKTSLNWRNDPHALRLFGFEIQNEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WY46</accession>
    <name>A0A0P6WY46_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Imidazole glycerol phosphate synthase subunit HisF</fullName>
            <ecNumber evidence="9">4.3.2.10</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">IGP synthase cyclase subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">IGP synthase subunit HisF</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">ImGP synthase subunit HisF</fullName>
            <shortName evidence="9">IGPS subunit HisF</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">hisF</name>
        <name evidence="11" type="ORF">ADN00_17460</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 9">IGPS catalyzes the conversion of PRFAR and glutamine to IGP, AICAR and glutamate. The HisF subunit catalyzes the cyclization activity that produces IGP and AICAR from PRFAR using the ammonia provided by the HisH subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + L-glutamine = 5-amino-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide + D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate + H(+) + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:24793"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58475"/>
            <dbReference type="ChEBI" id="CHEBI:58525"/>
            <dbReference type="EC" id="4.3.2.10"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 5/9.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 9">Heterodimer of HisH and HisF.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9 10">Belongs to the HisA/HisF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.10" evidence="9"/>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064331.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17460"/>
    <dbReference type="EnsemblBacteria" id="KPL71468">
        <property type="protein sequence ID" value="KPL71468"/>
        <property type="gene ID" value="ADN00_17460"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.560"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000107">
        <property type="term" value="F:imidazoleglycerol-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04731">
        <property type="entry name" value="HisF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01013">
        <property type="entry name" value="HisF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006062">
        <property type="entry name" value="His_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004651">
        <property type="entry name" value="HisF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00977">
        <property type="entry name" value="His_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00735">
        <property type="entry name" value="hisF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9 10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9 10" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="7 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="9">
        <location>
            <position position="11"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL71468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="259" mass="27017" checksum="537827441A33C92B" modified="2016-01-20" version="1">MLAKRIIPCLDVADGRVVKGVHFENLRDAGDPVEQARIYDAAGADELVFLDISATPRGHATVIEMVGRVADQVFMPLTVGGGIRSVEDMRALLLAGADKVSLNSAAVRQPELLAEGAQRFGSQCIVLAVDARRVSTAGQAPRWEVVINGGRTPTGLDALEWVRRGVEIGAGEILLTSMDADGTLAGFDLALTRAVADAVSVPVIASGGAGTLAHFAEVLTQGRADAALAASLFHDGKLAIPDLKAYLQAQGVPVRPPRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WY69</accession>
    <name>A0A0P6WY69_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_17360</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064354.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17360"/>
    <dbReference type="EnsemblBacteria" id="KPL71495">
        <property type="protein sequence ID" value="KPL71495"/>
        <property type="gene ID" value="ADN00_17360"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.536"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="11"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="47"/>
            <end position="54"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL71495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="235" mass="25886" checksum="D5C755C0050F3999" modified="2016-01-20" version="1">MENQTQSPVLVKLREVVKTYHTPAGDFPALRGLSADFERGHLIGVIGKSGAGKSTLVNMLTGVDHLSSGEIWVDGVGVHALNENELALWRGRNVGVIYQSFQLLPNLTLLDNVMMPMDLCGLYHPQRSPQRAMELLDLVEMADQAFKIPSTISGGQQQRAAIARALANDPQLIVADEPTGSLDSATAETIFLLFERLVAQGKTIVMVTHDHSLARRMTRIYHIADGLWIDDEKDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WYP8</accession>
    <name>A0A0P6WYP8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CRISPR system Cms protein Csm2</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">CRISPR type III A-associated protein Csm2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_14270</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">This subunit may be involved in monitoring complementarity of crRNA and target RNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CRISPR-associated Csm2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000034">
        <property type="protein sequence ID" value="KPL73733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063704.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000034.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14270"/>
    <dbReference type="EnsemblBacteria" id="KPL73733">
        <property type="protein sequence ID" value="KPL73733"/>
        <property type="gene ID" value="ADN00_14270"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010149">
        <property type="entry name" value="CRISPR-assoc_prot_Csm2_III-A"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03750">
        <property type="entry name" value="Csm2_III-A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01870">
        <property type="entry name" value="cas_TM1810_Csm2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL73733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="127" mass="14494" checksum="48F1844F3879DBB3" modified="2016-01-20" version="1">MSVQQIMTADETGEKLVQFASETADKLVKASLTRAQIRNIFTEVRQIESLWGMNRADALRRLNMLKPKLAYQTARTPQMKDLQSVLSEAITLVSNAASDEEKDQRFERFMDLFEAILAYHRAKGGRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZ72</accession>
    <name>A0A0P6WZ72_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_13045</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000028">
        <property type="protein sequence ID" value="KPL75309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063462.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000028.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL75309">
        <property type="protein sequence ID" value="KPL75309"/>
        <property type="gene ID" value="ADN00_13045"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL75309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="158" mass="18316" checksum="91808B991DDECC3B" modified="2016-01-20" version="1">MNNSIDSLLKQPYDCLILVHPQIQILDEISEKIQSFGIKHYNVSRALGSALMTVSTAERDRFAQEWLKDLIRGLREEPVLISHPDLFFHPSLKIDFFTLIRQISRSKQMIVLWPGEYSTDTLSYAIPDHHHYRVWKISDSLRIQPKIIIYQISAAQGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZA7</accession>
    <name>A0A0P6WZA7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_16520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064145.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16520"/>
    <dbReference type="EnsemblBacteria" id="KPL72077">
        <property type="protein sequence ID" value="KPL72077"/>
        <property type="gene ID" value="ADN00_16520"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="150"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="219"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="258"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="303"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="333"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="369"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="395"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="427"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="452"/>
            <end position="471"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="509" mass="56182" checksum="86B2E5B45FF142F8" modified="2016-01-20" version="1">MFELSKVFLYFLIQQTAVVAFSLARSKALATFTGAGGYGLIAQATSLVLAFQVILSAGLGSGFVKLIAENASEQAAQARNRIASGMYLLGSITGLVGIVLTGLFSRSISEWVFNTPDYANYVLICVFTAFFVFQTLFFQNLFRGLLEWKTYTLVSILGTGASLFITVTLIGFFHIDGGIWALLISQAASFLVAVSFFRFKIFPRHTVDFWNFLPTHKDFRMLLGHIGPLVITQILLTLSNLVTRSLVIQQLGLEDNGIIQVSTGISDAYMGLILAILFSFILPKIASTLSAQPQAARQTQNDGLRFSLLIITPFLVTLLATREIWIPLLYSRAFLAAQGILVWQFLGDFFLVVRRCMNIDLVPAQRLKYLVLDSSLYAGGMILLAALLLPQLGVYTVVVASLIVNLLLTGLSLIYHHRRMLFRPDRASWTMLIKSGGLLGAGFTAALAIPHLAWRVAAMGLILLLMVVFLPQRGELEKAWREIIPGLLRQSRLVFHKSTASKKADQPMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZN0</accession>
    <name>A0A0P6WZN0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chemotaxis protein CheY</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_15855</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064007.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15855"/>
    <dbReference type="EnsemblBacteria" id="KPL72287">
        <property type="protein sequence ID" value="KPL72287"/>
        <property type="gene ID" value="ADN00_15855"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.876"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="6"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL72287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="123" mass="13961" checksum="7276BAD42CC16A0B" modified="2016-01-20" version="1">MAEKRKILHVEDNFENRILVRRILQASGYEVVEAENAIEALDVLTHFVPQLILMDINMPEVDGYTLTQQIKAKQSFTDTPIIAITANVMKGDREKSLQAGCNGYIEKPINVDTFVDQIEAYLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X108</accession>
    <name>A0A0P6X108_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_11555</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL75995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063172.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL75995">
        <property type="protein sequence ID" value="KPL75995"/>
        <property type="gene ID" value="ADN00_11555"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL75995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="104" mass="11909" checksum="C0B0AA1FAD86C89C" modified="2016-01-20" version="1">MRSEIERLFNELNSEPVETGFANLVEGLDIDINYYESYIAGMVTVWLNGSSLPFEQVDRGEDLNQRLDQAIECILRFKQRKCKIDQIVDLLLKNSSVHGSTKIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X1G6</accession>
    <name>A0A0P6X1G6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_14950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000036">
        <property type="protein sequence ID" value="KPL73086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063837.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000036.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14950"/>
    <dbReference type="EnsemblBacteria" id="KPL73086">
        <property type="protein sequence ID" value="KPL73086"/>
        <property type="gene ID" value="ADN00_14950"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="370"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="399"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL73086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="429" mass="48155" checksum="3CFDD70840FD281A" modified="2016-01-20" version="1">MSKEWHIPEGFSQVESKLPGVTVFAPVKQVNGSRDKLVTYTCPRCGAVTRYDIAAGGVACEHCGYVHAVQTQVAGKAAEEHEFRVDVMEKANHVQWTAGRKDLVCEQCGAATSVPENAISGTCSFCASNKIHIADLPVEELQPKYIIPFSINQNQLKTIVSNWLGKGWFHPQSLSSSATVNSFRGVYLPFWTFDAEINADWKALVGYERSERYYDAGSKEWKTRTTIDWRWEDGQVNQSFDDILIPGTRKVSQRILEEIQPFDLNALQSFSPDFLAGWQANHFDLSLQEAWDTAKDKMREKNREACYADIPTHHVRNFSMSADFANETWRYIFLPVFLSTYHFEEKKYQVMINGQTGEIAGQKPVEWWKIWAAIAASLSPGFLLLLIGLPLLLAGGIGIVPLILGFVLLVAGIIFSVSLYKKAVESEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X240</accession>
    <name>A0A0P6X240_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Rhodanese domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_11405</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063168.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76589">
        <property type="protein sequence ID" value="KPL76589"/>
        <property type="gene ID" value="ADN00_11405"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="SSF52821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="1">
        <location>
            <begin position="29"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="119" mass="12545" checksum="FE03E99B94DE7677" modified="2016-01-20" version="1">MNQSPSAVVDAAAGDLPLEVSVAQAADLREQGVLMLDVREPEEWREAHIPGATLIPLGQLAGRVDELPKDQSIVVVCRSGNRSAVGRDILLEAGFEQVTSMAGGMNDWKAAGYETASGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X2K9</accession>
    <name>A0A0P6X2K9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09775</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062816.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76881">
        <property type="protein sequence ID" value="KPL76881"/>
        <property type="gene ID" value="ADN00_09775"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="136"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="185"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="215"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="240"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="271" mass="29883" checksum="A4150F4062616561" modified="2016-01-20" version="1">MKLDRNFTTHENEQTARDLISQYLLQQGYQQTSSQPNLIFERGSNMGSMTSFSTKRWKVVVTVQTRPSDEGGSQVSVSFDINTTGQWVVKREVNFWNKELEGLIAAACGSDVEIPTQTQLENKLVLEKRHSEGSKWFYWIAGLSVINSVILLMGGSINFLVGLGITQIVDAVSFVISEEVSPNAVLVVKSVAFLFNLGIAGIFVLLGLLSKRSKWGFIIGIVIYGLDALIFLIVPDFLSIAFHCLALFGLFGGLKAFGEIQKQKALEPAIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X2L2</accession>
    <name>A0A0P6X2L2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_09830</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062826.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09830"/>
    <dbReference type="EnsemblBacteria" id="KPL76891">
        <property type="protein sequence ID" value="KPL76891"/>
        <property type="gene ID" value="ADN00_09830"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2424"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="253" mass="27947" checksum="EF1EA66BE760A164" modified="2016-01-20" version="1">MHPHLLLKRLDEIGGSLARSGRALALIGCGSVGLELERLDEYSDLDFLAIVEPGAKQSYLDDLSWLSDLCPIAYCFANTADGYKLLYEDGIFCEFGVIEIDELPTIPFAPGRVVWKKEGVPDNISQPSVTTGSPPKRSQEWLLGEALTNLLVGLAREKRGEKLSATRFSQGYAVDRVVELAESIETAQAASRDIFINERRFEQRFPRLARELGACLQGYERNPQSALAILSLLEQHFEVSPAMANAIREMCGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X2P1</accession>
    <name>A0A0P6X2P1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10225</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062902.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10225"/>
    <dbReference type="EnsemblBacteria" id="KPL76955">
        <property type="protein sequence ID" value="KPL76955"/>
        <property type="gene ID" value="ADN00_10225"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="12"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="172" mass="19335" checksum="02452F4B24A1E610" modified="2016-01-20" version="1">MPSSEILRTPRLLLRYQTPADIPPLIALWRDPEVTRFMGGPRDLQRLQTAFDETQANPTAETYDLWPLVELSSGQTIGHCGLLDKEVDGKAEIELVYVLARSAWGQGYASEIGAALVAHAFERMGLRRLIALIEPQNAPSERVALRLGMRLEKEVIRPSGEPRRVYALEKME</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X2V8</accession>
    <name>A0A0P6X2V8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SH3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_10440</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10440"/>
    <dbReference type="EnsemblBacteria" id="KPL77073">
        <property type="protein sequence ID" value="KPL77073"/>
        <property type="gene ID" value="ADN00_10440"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036028">
        <property type="entry name" value="SH3-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001452">
        <property type="entry name" value="SH3_domain"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50044">
        <property type="entry name" value="SSF50044"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50002">
        <property type="entry name" value="SH3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0728">SH3 domain</keyword>
    <feature type="domain" description="SH3" evidence="2">
        <location>
            <begin position="41"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022443"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="97" mass="10961" checksum="D1DF9BDA1B5C8FE1" modified="2016-01-20" version="1">MIISKGDVLQAETRPSEWPGWVWVTTSNQVSGWMPLAYLDPDGAAWRAVCDYRDVELSVQPADTLEVLYTQDQWAWCQPAQGEPGWVPLAVLERLNT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X343</accession>
    <name>A0A0P6X343_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Beta sliding clamp</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">ADN00_12900</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP-independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of replication as well as for processivity of DNA replication.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Forms a ring-shaped head-to-tail homodimer around DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the beta sliding clamp family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063430.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000027.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12900"/>
    <dbReference type="EnsemblBacteria" id="KPL75534">
        <property type="protein sequence ID" value="KPL75534"/>
        <property type="gene ID" value="ADN00_12900"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1275"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009360">
        <property type="term" value="C:DNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00140">
        <property type="entry name" value="beta_clamp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001001">
        <property type="entry name" value="DNA_polIII_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022635">
        <property type="entry name" value="DNA_polIII_beta_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022637">
        <property type="entry name" value="DNA_polIII_beta_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022634">
        <property type="entry name" value="DNA_polIII_beta_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30478">
        <property type="entry name" value="PTHR30478"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00712">
        <property type="entry name" value="DNA_pol3_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02767">
        <property type="entry name" value="DNA_pol3_beta_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02768">
        <property type="entry name" value="DNA_pol3_beta_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000804">
        <property type="entry name" value="DNA_pol_III_b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00480">
        <property type="entry name" value="POL3Bc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00663">
        <property type="entry name" value="dnan"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 9" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="5 9" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DNA_pol3_beta" evidence="10">
        <location>
            <begin position="4"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_pol3_beta_2" evidence="11">
        <location>
            <begin position="131"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="DNA_pol3_beta_3" evidence="12">
        <location>
            <begin position="254"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KPL75534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="389" mass="41789" checksum="DD7E62FC131973CE" modified="2016-01-20" version="1">MASKVTVQKNTFAESLAIVGRAIASHTHLPVLGNILISKEESQLRLSATDLTIGVSVWMDAKMDGDVGLTLPAKTLTDVVNSFTEPEVTFSVNGKPEAALKCGTYKGVVKGMEAEEFPKMPEFDTSGGIPIDAATLKEMIRAVAFAASVDESRPVLTGVLLQMEGKTISLAATDGFRLALHKTEVALSLEKKQLIIPASVLKEVLRILSATKASTVTLYLPSAGSQVVLRLDDSRRVQIVSQLIDGKFPDYQVIIPKGYKTRTIVDAGELLKACKQAGIIAREGSNVVRFHLQPGTDQSGKVKLLAASAETGESEIELDATVEGQELEIAFNVKFLQDALEAISTKRVVIETNAHNTPAMIRPAGCVASPTGEEQDAYRYVLMPMHIDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X3Z8</accession>
    <name>A0A0P6X3Z8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">4Fe-4S ferredoxin-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_12330</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063316.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12330"/>
    <dbReference type="EnsemblBacteria" id="KPL76119">
        <property type="protein sequence ID" value="KPL76119"/>
        <property type="gene ID" value="ADN00_12330"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3946"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028261">
        <property type="entry name" value="DPD_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002489">
        <property type="entry name" value="Glu_synth_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036485">
        <property type="entry name" value="Glu_synth_asu_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00037">
        <property type="entry name" value="Fer4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14691">
        <property type="entry name" value="Fer4_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01493">
        <property type="entry name" value="GXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69336">
        <property type="entry name" value="SSF69336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="737"/>
            <end position="766"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL76119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="774" mass="84017" checksum="0819786237C4B8F8" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X4L7</accession>
    <name>A0A0P6X4L7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF2344 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063611.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000032.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13820"/>
    <dbReference type="EnsemblBacteria" id="KPL74366">
        <property type="protein sequence ID" value="KPL74366"/>
        <property type="gene ID" value="ADN00_13820"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018768">
        <property type="entry name" value="DUF2344"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10105">
        <property type="entry name" value="DUF2344"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03936">
        <property type="entry name" value="sam_1_link_chp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2344" evidence="1">
        <location>
            <begin position="3"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="211" mass="23657" checksum="9E8E0F2BB3F46E38" modified="2016-01-20" version="1">MIRVRFTYAKTEDLRYTSNLDVHRVWERALRRAGLPLAYSQGFNPQPRINQACPLPLGITSQCEILEAWLEEDLPLEDIACALNPALPSGFKLLRTDPIDLQAPRVQTLVASSTYRALLLDPVDEAALRQRAAELLAQPSLPMNRRGKDYDLRPLIETLSIESGADGRPAILMRLSARESATGRPEEVLKALGLDPSLARQERVELHLKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X559</accession>
    <name>A0A0P6X559_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_18330</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064498.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70022">
        <property type="protein sequence ID" value="KPL70022"/>
        <property type="gene ID" value="ADN00_18330"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007016">
        <property type="entry name" value="O-antigen_ligase-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04932">
        <property type="entry name" value="Wzy_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="169"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="197"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="220"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="254"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="336"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="376"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="400"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="431"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL70022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="644" mass="70033" checksum="0EED12FDEC061879" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5B0</accession>
    <name>A0A0P6X5B0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PpiC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_13145</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000030">
        <property type="protein sequence ID" value="KPL75176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063480.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000030.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13145"/>
    <dbReference type="EnsemblBacteria" id="KPL75176">
        <property type="protein sequence ID" value="KPL75176"/>
        <property type="gene ID" value="ADN00_13145"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000297">
        <property type="entry name" value="PPIase_PpiC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027304">
        <property type="entry name" value="Trigger_fact/SurA_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109998">
        <property type="entry name" value="SSF109998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50198">
        <property type="entry name" value="PPIC_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0697">Rotamase</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5007782307" description="PpiC domain-containing protein" evidence="3">
        <location>
            <begin position="25"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="PpiC" evidence="4">
        <location>
            <begin position="184"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="33"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="33"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL75176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="308" mass="33333" checksum="FF706A9CBAC04AAC" modified="2016-01-20" version="1">MLTKTISISKTVLFAILLAGALLAGCTMNPAGTTPAGENPTDPVSEATNTPFQPSPTPRPLAARVNGRDISLAAYQVSLNMLTAADAEQGITRAEEEQRELVLGDLVDRALLAAAAEASGYTLDEAAVSERVSQLETEMGGVDALAAWQAQYGLDRESFVEVLRESELAAWQRDQIISSVPERMEQVHARQIRVREEETIQDILGNLNSGAEFGKVARQYDPTTGGDLGWFPRGYLLQPEVEEAAFALQAGEVSGIIHSQVGYHLVQVIEREAERELTLEARAVLQQKALSAWLDAQRASAQVEVLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X629</accession>
    <name>A0A0P6X629_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_13235</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063497.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000031.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74805">
        <property type="protein sequence ID" value="KPL74805"/>
        <property type="gene ID" value="ADN00_13235"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="80"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="24"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL74805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="124" mass="13277" checksum="5F6B15C3414B059D" modified="2016-01-20" version="1">MTEFNSFPDPFESSDAPQQPAEPAPTSNEMPIPPGPVASEPPAPATEPEIPYTPGEVIPPMQEAYTPPAAPPAKKSNKTIWIILAVVLILICLCCVILAIVAASNYENIMKDFNLTLLTHLLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-08-12" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X747</accession>
    <name>A0A0P6X747_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ABC transmembrane type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_05780</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78875">
        <property type="protein sequence ID" value="KPL78875"/>
        <property type="gene ID" value="ADN00_05780"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="102"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="130"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="175"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="232"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="65"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL78875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="269" mass="28779" checksum="8BE347CEF6C5EF99" modified="2016-01-20" version="1">MLVFAVVTPFIWMVISSISPQVELSAKPPHWIPNNPTLARYRSLIFGSQSGAAIPAATEKFLRGMLSSLIVSISTTAVCVVAGTMAAYALARLPIPGKPRVLVGILSAQMVPVIVIIIPLYLLLRSLADTWTGLIVLYAGFMLPTVIWIMHSYFLSIPESLEEAAMIDGCSRLSALMRVILPLSGPGLVAVSAFTFLSSWNEFFMALIFTGARTKTITVVVTEFSSQFGVDFGLMATGGVIGSLPPLILAFLLQRYIVAGLTAGALKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7J9</accession>
    <name>A0A0P6X7J9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH luxR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_03730</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061622.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79012">
        <property type="protein sequence ID" value="KPL79012"/>
        <property type="gene ID" value="ADN00_03730"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041617">
        <property type="entry name" value="TPR_MalT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17874">
        <property type="entry name" value="TPR_MalT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="835"/>
            <end position="900"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="903" mass="98644" checksum="EAE2E5BDFC113169" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7V5</accession>
    <name>A0A0P6X7V5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chloramphenicol acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_07820</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000020">
        <property type="protein sequence ID" value="KPL78076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062431.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000020.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78076">
        <property type="protein sequence ID" value="KPL78076"/>
        <property type="gene ID" value="ADN00_07820"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2855"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008811">
        <property type="term" value="F:chloramphenicol O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001707">
        <property type="entry name" value="Cmp_AcTrfase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38474">
        <property type="entry name" value="PTHR38474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00302">
        <property type="entry name" value="CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000440">
        <property type="entry name" value="CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01059">
        <property type="entry name" value="CAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000440-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="215" mass="25097" checksum="E29B84FFA523F04C" modified="2016-01-20" version="1">MRQIDIDTWPRREHFNLYNSFEFPHFTLCANVDLTNLLSFVREKRVSLNVAIIYLVTRAANQIPEFRYRIRSGSVIEHEVVHPSTTILGKDDVFSFCTLNYTTDFSQFLSRALEKIACVQKRPRLLEEDQQRDDLLFMTAIPWVSFTSIMHPMRLLPEDSVPRFAWGKYFEEGSKIKMPLSVQGHHALMDGLHAGRFYEEVQQTFHDPKTVITGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X887</accession>
    <name>A0A0P6X887_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_16920</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL71384">
        <property type="protein sequence ID" value="KPL71384"/>
        <property type="gene ID" value="ADN00_16920"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL71384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="136" mass="15533" checksum="AA2B9377AF46D5D9" modified="2016-01-20" version="1">MIEKLENVTMEKEKITIIEGPPPTFEQIDDGWAMGLNEGPSLYDLAITRLRTFNGAALVERCYRAWNKQDSIFLHYKNDLGLEESAPILAARSVETEDGQVLILWVRRNPGEDDDDIDFDDDEELDFGDDDPEDLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X8C9</accession>
    <name>A0A0P6X8C9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_07180</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07180"/>
    <dbReference type="EnsemblBacteria" id="KPL78350">
        <property type="protein sequence ID" value="KPL78350"/>
        <property type="gene ID" value="ADN00_07180"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3255"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="40"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="135"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="167"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="247"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="292"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="342"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="369"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="420"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="445"/>
            <end position="463"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL78350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="620" mass="68252" checksum="76B03D0274EAD82D" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9K2</accession>
    <name>A0A0P6X9K2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Electron transfer flavoprotein subunit alpha</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_05805</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ETF alpha-subunit/FixB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78752.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062024.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05805"/>
    <dbReference type="EnsemblBacteria" id="KPL78752">
        <property type="protein sequence ID" value="KPL78752"/>
        <property type="gene ID" value="ADN00_05805"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1637"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01715">
        <property type="entry name" value="ETF_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014730">
        <property type="entry name" value="ETF_a/b_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001308">
        <property type="entry name" value="ETF_a/FixB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033947">
        <property type="entry name" value="ETF_alpha_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014731">
        <property type="entry name" value="ETF_asu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43153">
        <property type="entry name" value="PTHR43153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01012">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00766">
        <property type="entry name" value="ETF_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000089">
        <property type="entry name" value="Electra_flavoP_a"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00893">
        <property type="entry name" value="ETF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ETF" evidence="2">
        <location>
            <begin position="72"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005817"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78752.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="403" mass="44364" checksum="71D960BB9B450EFB" modified="2016-01-20" version="1">MAKIIIHQEQARDLQSLTHLCPFGAIVIENDCLEITAGCKMCKLCVKNGPQGVFEFVAEDQAQIDKSQWRGIAVYVEHQEGNIHPVTLELIGKARELAGKIDQPVYALFAGAAIRENAESLRDYGVDEIFVYDHPALKFFRIEPYAAVFEDFVQQVKPSAILVGGTPVGRSLAPRVAARFRTGLTADCTKLDMQPNTDLDQIRPAFGGNIMAHIRTQNSRPQFATVRYKIFAAPGRLEHPVGKVTLMPVDDEQLRSKITVLEIKPKPAVQHLEDAEVIVVAGRGLKREQDMEMINTLAERLGGQVAGTRPIIEAGWVDPRRQIGLSGRTVKPKLLITCGVSGSVQFTAGMRGAERIIAINRDPHAPIFNCAHYGLVGDVYEIIPRLLSELPALQNGIAQREVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9W5</accession>
    <name>A0A0P6X9W5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N_BRCA1_IG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_11180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76524.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063097.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76524">
        <property type="protein sequence ID" value="KPL76524"/>
        <property type="gene ID" value="ADN00_11180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14947">
        <property type="entry name" value="NBR1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032350">
        <property type="entry name" value="N_BRCA1_central"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16158">
        <property type="entry name" value="N_BRCA1_IG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N_BRCA1_IG" evidence="1">
        <location>
            <begin position="122"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76524.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="219" mass="24061" checksum="04995F3A383AF194" modified="2016-01-20" version="1">MKVSIWDILSVVGLLALIGLVLVFAQILINPSSALNPFPPPELPPTIELPSATPTQRSLPPTWTATVSALIMPTLAPSSTPLPTATRFTVATWTPSPTPTPLATSTPTPGPNQARLISQNPPDGAVLSPGQEFDMVWKVENNGTNTWDKDDYTFRYSSGQEIHKYDEYALREDVSPGERYDFIVDMAAPNEKGSYSLAWKLVDEDGKTFYTMTFSFRVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XA39</accession>
    <name>A0A0P6XA39_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Mannose-6-phosphate isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063038.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10210"/>
    <dbReference type="EnsemblBacteria" id="KPL77069">
        <property type="protein sequence ID" value="KPL77069"/>
        <property type="gene ID" value="ADN00_10210"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2506"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="1">
        <location>
            <begin position="9"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="118" mass="13748" checksum="D2DABF0F10F637AF" modified="2016-01-20" version="1">METINLAEKFSRFSEQWQPKIVGELNDAYVKLAKLQGEFVWHHHDEEDELFMVIKGRLLIKLRDRDLWIGEGELAIIPRGVEHCPVAVEEAHVLMLEPKSTRNTGNVENERTVEAEWI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAF4</accession>
    <name>A0A0P6XAF4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_04270</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061719.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04270"/>
    <dbReference type="EnsemblBacteria" id="KPL79091">
        <property type="protein sequence ID" value="KPL79091"/>
        <property type="gene ID" value="ADN00_04270"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039428">
        <property type="entry name" value="NUOK/Mnh_C1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00420">
        <property type="entry name" value="Oxidored_q2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="33"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="60"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL79091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="103" mass="10827" checksum="4B251EDEF7894CBA" modified="2016-01-20" version="1">MNLNAASIAFIAVIGLLGIGLYGVLITRNLIKVVVALQVLVKGAMIFIVLAGHLVGQIEIGQSMALTVIVADTIVAVIGLALAVQIRRHFGTLDVKALTTLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAN2</accession>
    <name>A0A0P6XAN2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADP oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_15440</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063930.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15440"/>
    <dbReference type="EnsemblBacteria" id="KPL72216">
        <property type="protein sequence ID" value="KPL72216"/>
        <property type="gene ID" value="ADN00_15440"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.790"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008901">
        <property type="term" value="F:ferredoxin hydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.645.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001501">
        <property type="entry name" value="Ni-dep_hyd_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018194">
        <property type="entry name" value="Ni-dep_hyd_lsu_Ni_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029014">
        <property type="entry name" value="NiFe-Hase_large"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00374">
        <property type="entry name" value="NiFeSe_Hases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56762">
        <property type="entry name" value="SSF56762"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00507">
        <property type="entry name" value="NI_HGENASE_L_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL72216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="476" mass="53256" checksum="938C7217AE74E9A9" modified="2016-01-20" version="1">MVAKKITIEPVTRIEGHAKITIRMKDDGKVDHAYLHINEFRGFEKFCEGRMVFEMPMITPRICGICPVSHHLAAAKAGDDLLSCPPPRPASLLRELMHMGQVIQSHGMHFFELAGPDLLLGFDADPAVRNVVGLIQTAPDIAVKAVQLRKFGQDIIYRLGGRRIHPVFAIPGGVNKALSQEDRDAILAGVDQAIATTQLGVQIMRDWAEKNAEDIQKFAVFPTGYFGLVTPNNSLELYDGDIRLIDRNRQQLEKFDGRNYLDYIAEHVESWTYLKFPYYKKMGYPQGVYRVGPLGRLNASDQISTPIANEEHKRFKALNNGAPVENTLYFHYARLIEILFAIEKARELLEDEDILSNDVLNTRQTNKGEGVGVIEAPRGTLFHHYWANEDGKLTKVNLIVATGHNNWAMTEAVDSVAKTYIDGNEVREGLLNRVEAAVRAHDPCLSCSTHAVGQMPMVIDIVDSQGHLLQTLSRNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBU6</accession>
    <name>A0A0P6XBU6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_15635</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063964.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15635"/>
    <dbReference type="EnsemblBacteria" id="KPL72247">
        <property type="protein sequence ID" value="KPL72247"/>
        <property type="gene ID" value="ADN00_15635"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009666">
        <property type="entry name" value="Uncharacterised_Ycf35"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06868">
        <property type="entry name" value="DUF1257"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0934">Plastid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="142" mass="16128" checksum="A2FCAE9955E4C635" modified="2016-01-20" version="1">MSKYREIKTEFRNPTSLKKALDEMGVKYEASLDARSNSITLWSNWKTWGGESQAVAIAIQKDEASRVGLGCYDGVGFHWNGSSYDLVADHMDENLNSVVSQMNKLRQSYAKQEIRRQAYQRGYGVQEAVGQDGVIRMTLVRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBV3</accession>
    <name>A0A0P6XBV3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA mismatch repair protein MutS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_08990</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062662.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08990"/>
    <dbReference type="EnsemblBacteria" id="KPL77264">
        <property type="protein sequence ID" value="KPL77264"/>
        <property type="gene ID" value="ADN00_08990"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4032"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS_family"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="PTHR11361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_MISMATCH_REPAIR_2" evidence="3">
        <location>
            <begin position="321"/>
            <end position="497"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL77264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="497" mass="56377" checksum="4705C209DDFF137F" modified="2016-01-20" version="1">MKAFLMFRDQDFGPHCPLPLQAKALVQDLELKTLFDAMAQGDNFVFDIARTSILSGTEDIDTILYRQDILKDCLKYPSVIREIYQLPIEAKTNKQKGWLGIYGHYPTAILSGSHEFIKMLFELLKRLRGIADDNAALFESEGFKRFFAMIQQELDDNYFAIAENHLKELKFREGVMISVDLGQGNEGTNYILRKPLSTKWWKEIFIRENEAYSIYIADRDDAGARALGELKDTGVDLVANALAQSADHIDNFFKMLQIELGFYIGCINLHEQLAQMGCATCLPLPAPTNERRHSFHGLYDICLALTKKQKIVGNEVNADQKDLVMITGANQGGKSTFLRSIGLAQLMMQSGMFTPADDFTANLCTGVFTHYKREEDKTMTSGKLDEELSRMDDIADTISSNSLILFNESFAATNEREGSEISRQITSALLEQDVKVFFVTHQYDLAHSFFDRGLENAIFLRAERKEDGERTYKLIEAKPLPTSFGEDVYHIVFQDDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDK4</accession>
    <name>A0A0P6XDK4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_00505</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060996.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00505"/>
    <dbReference type="EnsemblBacteria" id="KPL81051">
        <property type="protein sequence ID" value="KPL81051"/>
        <property type="gene ID" value="ADN00_00505"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14602">
        <property type="entry name" value="Hexapep_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="24"/>
            <end position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL81051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="246" mass="26940" checksum="0B5148E6C7B4C6E5" modified="2016-01-20" version="1">MFRQLKTYIGRQAHNLVRYLWEQFWFFCIGWVPTLAGIGMRGIFYRLIMKMHGWVAIEKNVRIRFASGLHLENGVYLDENTYLHACPAGIHIGERSIIMHGAVLHVYNFRGLPDAGIWIGKDSLVGEYSVIRGQGGVHIGDRVYTSPFTQIIAVNHVFDDPNKSFVDQGITAEGIVIDDDVWIGSGAIVLDGVTIGKGSVIAAGAVVTKDIPPHSVAAGVPAKVIRSIDGTDLTGSKHVYFHNSGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGA0</accession>
    <name>A0A0P6XGA0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_18885</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064596.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70109">
        <property type="protein sequence ID" value="KPL70109"/>
        <property type="gene ID" value="ADN00_18885"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010026">
        <property type="entry name" value="Phage_holin_LL-H"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09682">
        <property type="entry name" value="Phage_holin_6_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="14"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="127" mass="14057" checksum="FAA946DD01A2FC70" modified="2016-01-20" version="1">MKFEAFLSEFVQQLLLYLLPILAAALASWLIVQVSKGLAELKSARPDVYQELMWVAKGVVQAAEQAGAAGLITDKKNYAINIAEKWLAAKGWHIDLDLIDAAVEQAVWDEINKYKVLPVSTLTEVSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGD4</accession>
    <name>A0A0P6XGD4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_19110</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_19110"/>
    <dbReference type="EnsemblBacteria" id="KPL70145">
        <property type="protein sequence ID" value="KPL70145"/>
        <property type="gene ID" value="ADN00_19110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00805">
        <property type="entry name" value="Pentapeptide"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13599">
        <property type="entry name" value="Pentapeptide_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL70145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="452" mass="51018" checksum="8016524E2B646AFC" modified="2016-01-20" version="1">MSNVNFWGNEMEEIDSRPSEGEQIEQSKPELKTFWPVWTGFGEFTDYEGKFHRGKTLWDWLELLIIPIVLAAGALFINYSLTQQGYENAEKNAQIEREINLENHREALLQSYLDKMGEILLDLDLGQNINNDSTELRSLAQARTFTTIRQLDGPRKNIIIEFLYETRLITPTKSNQPYINLQRVDLSNSNWVSKNLNYIDLSGADFDHANISGSNFNFSNFSFTWLDTASLMGSNFIGADLSSSTFSNASLMGVNFSHANLMEADFYKANMWLTTMVGANLTYAYPVEAVLKNCDLSCVTMDQSNFEKAALSGTKISYANIDQSYFHHAKMEGVSLYQAEVVDSCFWRATLSEADFRYSVISRSDLSETEMQKADFSNSVLSEVIFKYSDLSDSKFGNASLYKVDFENANLQNADFTGADLTESDFTKANLRGAIITDEQLSQAASIEGIKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGE9</accession>
    <name>A0A0P6XGE9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063586.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000032.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74347">
        <property type="protein sequence ID" value="KPL74347"/>
        <property type="gene ID" value="ADN00_13680"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="240"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="345"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="380"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="404"/>
            <end position="423"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="432" mass="49123" checksum="1B2D6043774C9BC5" modified="2016-01-20" version="1">MKPLSQTPVNRVFLACFILIASYFYWQGVDGVPFHPDEATQLYMSADFQQYITDPFSMAWRPEQRYDPVIHFRLLDAPLTRYAAGAVLYFTGREPLPVDWVWSQNWQTNVNRGALPDAAMLHAGRLAVAWVFPFSMLLLYAIAAGVMDYRAAWISLLLFAGNALVLLHTRRVMTESFLTFFVLLNIFMLIYVKPPHLPWLGLAAALAICAKQSAAALIPLNLLAIVWITQKEYQSWKRTLRAVLLFLFLFALIFMLLNPVFWAHPIPSLQAAATERQQLLQSQIETISRQDPDQILTSVPMRAGSLIAHTFFTPPMIAESRNYYAATLEAESIYFDQPLHSRYRAMFPGTIYLIFTLIGLATAVYQTVTRQNPPDSRIPWLLLSLAFLAGGLIAVVPLTWQRYVMPLIAFPCIFAAWPFYRLLCANQTIGQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGH3</accession>
    <name>A0A0P6XGH3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_04170</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79236.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04170"/>
    <dbReference type="EnsemblBacteria" id="KPL79236">
        <property type="protein sequence ID" value="KPL79236"/>
        <property type="gene ID" value="ADN00_04170"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.190"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="10"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="46"/>
            <end position="53"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL79236.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="245" mass="27230" checksum="00587303830B1CF9" modified="2016-01-20" version="1">MAAASKKFVIETQDVAKLYKSGETTVRAVDGVSMRIQPGEFIGLVGPSGSGKTTMLAMLAALLTPSEGEVWIDGTAISQLPEAERVRFRRERIGFTFQSNNLVPYLTVLENVQLMLQLKNGRLSSIDKERARYLLVRLGLENRLNSLPQQLSGGQRQRVAIARSLVHGPSVVLADEPTASLDTERAYQVVEIFANLIHEENKAGIMVTHDLRMCQYVDRVIQMVDGKVDTELNQREEILEFISCA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGK4</accession>
    <name>A0A0P6XGK4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Aminotransferase DegT</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_06555</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the DegT/DnrJ/EryC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062161.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06555"/>
    <dbReference type="EnsemblBacteria" id="KPL78864">
        <property type="protein sequence ID" value="KPL78864"/>
        <property type="gene ID" value="ADN00_06555"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1815"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00616">
        <property type="entry name" value="AHBA_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000653">
        <property type="entry name" value="DegT/StrS_aminotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30244">
        <property type="entry name" value="PTHR30244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01041">
        <property type="entry name" value="DegT_DnrJ_EryC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000390">
        <property type="entry name" value="PLP_StrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="186"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL78864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="380" mass="43140" checksum="09943DAE83B6C653" modified="2016-01-20" version="1">MEPIQLFVPTFRIEESLEEIRVCLEKGWTGLGFKTIEFEKAWLDFTGLENAHFVDSATAGLHLAVKLLKLHGGWADGDEVITTPLTFVSSNHAILYENLKPVFADVDEYLCLDPASVEALITPHTRAVLYVGLGGNPGQLDRIVEICKKHHLKLILDAAHMTGTRLHGRHVGWQADVSVFSFQAVKNLPTADSGMICFSDKALDAEVRKWTWLGINKDTYSRTVSSEGTYKWYYDVEFVGHKYHGNSIMAALGLVSIKYVESDNEYRRKIAGWYDELFAKEPRIGLVKMAPDSVPSRHLYQVLVDERDRAMSYLNEHKIYPGVHYRDNTVYRMYEYADGTCPNARSASDRIISLPLHLRLTEQDVQRVANTLIEFVQLSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGX0</accession>
    <name>A0A0P6XGX0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Riboflavin biosynthesis protein RibD</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_14160</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063679.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000033.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14160"/>
    <dbReference type="EnsemblBacteria" id="KPL74140">
        <property type="protein sequence ID" value="KPL74140"/>
        <property type="gene ID" value="ADN00_14160"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1933"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008703">
        <property type="term" value="F:5-amino-6-(5-phosphoribosylamino)uracil reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002734">
        <property type="entry name" value="RibDG_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01872">
        <property type="entry name" value="RibD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="SSF53597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RibD_C" evidence="1">
        <location>
            <begin position="2"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="192" mass="21424" checksum="80D35BE74280DC9F" modified="2016-01-20" version="1">MRKLIVLEHISLDGVIQAPGGPDEDPSGGFAHGGWISPFSDEILGTLLRRQMNTPFDLLLGRTTFEIWEAYWPEHSDVWPEVNQATKYVASNNRTYSQWQPSVFLSGDIAEKVASLKQQQGPDLHVWGSGNLIQTLIKHNLVDTFWLMIYPITLGAGKRLFSDGALPMAFKVTESTITPNGVVVMNYERAPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XI41</accession>
    <name>A0A0P6XI41_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">tRNA-specific 2-thiouridylase MnmA</fullName>
            <ecNumber evidence="7">2.8.1.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">mnmA</name>
        <name evidence="8" type="ORF">ADN00_02125</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the 2-thiolation of uridine at the wobble position (U34) of tRNA, leading to the formation of s(2)U34.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>AH2 + ATP + S-sulfanyl-L-cysteinyl-[protein] + uridine(34) in tRNA = 2-thiouridine(34) in tRNA + A + AMP + diphosphate + H(+) + L-cysteinyl-[protein]</text>
            <dbReference type="Rhea" id="RHEA:47032"/>
            <dbReference type="Rhea" id="RHEA-COMP:10131"/>
            <dbReference type="Rhea" id="RHEA-COMP:11726"/>
            <dbReference type="Rhea" id="RHEA-COMP:11727"/>
            <dbReference type="Rhea" id="RHEA-COMP:11728"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61963"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:87170"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.8.1.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the MnmA/TRMU family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.13" evidence="7"/>
    <dbReference type="EMBL" id="LGCL01000009">
        <property type="protein sequence ID" value="KPL79784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061313.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000009.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02125"/>
    <dbReference type="EnsemblBacteria" id="KPL79784">
        <property type="protein sequence ID" value="KPL79784"/>
        <property type="gene ID" value="ADN00_02125"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2747"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016783">
        <property type="term" value="F:sulfurtransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01998">
        <property type="entry name" value="tRNA_Me_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.280">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00144">
        <property type="entry name" value="tRNA_thiouridyl_MnmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023382">
        <property type="entry name" value="Adenine_a_hdrlase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004506">
        <property type="entry name" value="tRNA-specific_2-thiouridylase"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00420">
        <property type="entry name" value="trmU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="2 7" id="KW-0820">tRNA-binding</keyword>
    <feature type="region of interest" description="Interaction with tRNA" evidence="7">
        <location>
            <begin position="150"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with tRNA" evidence="7">
        <location>
            <begin position="306"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="103"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine persulfide intermediate" evidence="7">
        <location>
            <position position="200"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="12"/>
            <end position="19"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Interaction with tRNA" evidence="7">
        <location>
            <position position="128"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with tRNA" evidence="7">
        <location>
            <position position="339"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Alternate" evidence="7">
        <location>
            <begin position="103"/>
            <end position="200"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL79784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="359" mass="39787" checksum="640759ADFB4E1FEA" modified="2016-01-20" version="1">MTRDNSPKVAVAMSGGVDSSLAAALLKSDGYDVAGFMLKTWKAEHLLGSHSVIDPIESARSVANTLGIPFEVIDIQAEFREKVVHSFIKDYQNGLTPSPCVFCNRAIKWKAMLDAADRIGAEFVATGHYARVIRDPEGLFELRTGKDGSKDQAYMLCMLTQAELSRTIFPLGEYTKRRVRELAQEFGLPTASQQDSQDLCFLPDGDYRGFLLRYSPEVRKPGKIVDQQGNQLGEHEGLAFYTIGQRKGLGIYRPEPLYVLEKNLERNEVVVGTRAELGHQVMVVEGVNWISGRELDDGSVVDVKIRYKAKPVKGQITVTGKTTVKVEFKTPIRDITPGQIAVFYDDDRVLGGGVINSDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XJH8</accession>
    <name>A0A0P6XJH8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Flagellar basal body rod protein FlgB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_17080</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">Structural component of flagellum, the bacterial motility apparatus. Part of the rod structure of flagellar basal body.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">The basal body constitutes a major portion of the flagellar organelle and consists of a number of rings mounted on a central rod.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the flagella basal body rod proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71407.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064261.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17080"/>
    <dbReference type="EnsemblBacteria" id="KPL71407">
        <property type="protein sequence ID" value="KPL71407"/>
        <property type="gene ID" value="ADN00_17080"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.478"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030694">
        <property type="term" value="C:bacterial-type flagellum basal body, rod"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001444">
        <property type="entry name" value="Flag_bb_rod_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006300">
        <property type="entry name" value="FlgB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30435:SF12">
        <property type="entry name" value="PTHR30435:SF12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00460">
        <property type="entry name" value="Flg_bb_rod"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002889">
        <property type="entry name" value="Rod_FlgB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01396">
        <property type="entry name" value="FlgB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flg_bb_rod" evidence="7">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="65"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR002889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL71407.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="136" mass="14666" checksum="FBF9BE245484686F" modified="2016-01-20" version="1">MINRLFDDPAMQSAKMALDGLALRNQIISRNLANVDTPGYKAQSVDFESVIRRAIDRETGLTMNATQTGHIGKPSSSAASATLIRARSGGSTRADGNNVDVDNELIEMSETGIRYEAVSQQISKKLLLLKSIAASR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XJJ4</accession>
    <name>A0A0P6XJJ4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_17250</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064295.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17250"/>
    <dbReference type="EnsemblBacteria" id="KPL71435">
        <property type="protein sequence ID" value="KPL71435"/>
        <property type="gene ID" value="ADN00_17250"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.512"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="483"/>
            <end position="694"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL71435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="694" mass="76914" checksum="FB9CA523F70A91D4" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKZ8</accession>
    <name>A0A0P6XKZ8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_01640</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80598.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80598">
        <property type="protein sequence ID" value="KPL80598"/>
        <property type="gene ID" value="ADN00_01640"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1088"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="SSF81660"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="50"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="82"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="246"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="278"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="721"/>
            <end position="745"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="794"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="863"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="901"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="domain" description="Cation_ATPase_N" evidence="8">
        <location>
            <begin position="4"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL80598.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="926" mass="100967" checksum="F7782235E28D69F2" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XLY0</accession>
    <name>A0A0P6XLY0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ADN00_09385</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062732.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09385"/>
    <dbReference type="EnsemblBacteria" id="KPL77327">
        <property type="protein sequence ID" value="KPL77327"/>
        <property type="gene ID" value="ADN00_09385"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011620">
        <property type="entry name" value="Sig_transdc_His_kinase_LytS_TM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07694">
        <property type="entry name" value="5TM-5TMR_LYT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="36"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="67"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="98"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="126"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="163"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="8">
        <location>
            <begin position="225"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="9">
        <location>
            <begin position="274"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="8">
        <location>
            <begin position="328"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="9">
        <location>
            <begin position="402"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="9">
        <location>
            <begin position="532"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="311"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="574"/>
            <end position="615"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL77327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="637" mass="71997" checksum="53E22B2D4DA239A4" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XM53</accession>
    <name>A0A0P6XM53_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_18140</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL69991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL69991">
        <property type="protein sequence ID" value="KPL69991"/>
        <property type="gene ID" value="ADN00_18140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL69991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="78" mass="9041" checksum="308B869477D7F921" modified="2016-01-20" version="1">MPPLQDISIRECCKYNESGQVQILRKPPIVINPNKRFGSYGKKPKPTAIWREETTIISPEIKIKNQLNDQPIVKLRLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XN51</accession>
    <name>A0A0P6XN51_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SnoaL-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_08395</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062537.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08395"/>
    <dbReference type="EnsemblBacteria" id="KPL77885">
        <property type="protein sequence ID" value="KPL77885"/>
        <property type="gene ID" value="ADN00_08395"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037401">
        <property type="entry name" value="SnoaL-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12680">
        <property type="entry name" value="SnoaL_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SnoaL-like" evidence="1">
        <location>
            <begin position="263"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="368" mass="41895" checksum="D98B95C019BACD4E" modified="2016-01-20" version="1">MTLQGKSMMIWKVSRCEGGNPQAIASAAQAAGLSCVLLKIADGPKPYNIDGTPARDQLPALVEALRAKGLQVWGWHYVYGYNPQAEAQAAIQRMRELELDGYVINAEAEYKQTGKKQAAKTFMDLVRPALANTPIALTSYRWPSYHPQLPWREFLEKCDLNMPQVYWQSAHNPDSQLRRTLREFQALVPYRPIIPIGPMYKYGSWEPTPADISEFMETAEALNLAGVCFFEWYYARTILSPLWNTLSAYTWSPSLQPIDFPAQLIQAYNQQDYTRLYHLYHPDAVHISPDQTVQGHEGILRWYHSFFVDQFPSGKFTLTGASGNNTNRTFTWSAQGAKGSIMDGNDTLGILQNRISYHYSYYSIRKPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XNG7</accession>
    <name>A0A0P6XNG7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_14635</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000035">
        <property type="protein sequence ID" value="KPL73574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063774.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000035.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14635"/>
    <dbReference type="EnsemblBacteria" id="KPL73574">
        <property type="protein sequence ID" value="KPL73574"/>
        <property type="gene ID" value="ADN00_14635"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2093"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036086">
        <property type="entry name" value="ParB/Sulfiredoxin_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110849">
        <property type="entry name" value="SSF110849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL73574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="315" mass="36863" checksum="602F59AC663E2B16" modified="2016-01-20" version="1">MSNESTRSAVEQMARADFESAYRKGFWRSMLSWLAQEKNELLPFDEVRKSLPWRGEHWVGLRQIELDKVVGSVGRYRDFDRAFLPRQKRTERRWVSIDSAHLQEIVLPPIEVYKVGSVYFVKDGNHRVSVARERGQAFIDANVIEIDIPVEITPEMGINEVIARCEQVEFMQATRLAELREGAQIVLSVPGGYQKVLEHIGAHRYFMGINQQREVAWEEAVGDWYDQLYLPMVRVTEENGILKEFPGRTHGDLYLWVMEHWWYLREEYQAEVSLEAAAAHFAEEYSERPLPMLMRFLRGRMPPREEGGQTEENVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XNS2</accession>
    <name>A0A0P6XNS2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_14250</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000034">
        <property type="protein sequence ID" value="KPL73729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063700.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000034.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14250"/>
    <dbReference type="EnsemblBacteria" id="KPL73729">
        <property type="protein sequence ID" value="KPL73729"/>
        <property type="gene ID" value="ADN00_14250"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011742">
        <property type="entry name" value="CRISPR-assoc_prot_TM1812"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019016">
        <property type="entry name" value="Csx1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09455">
        <property type="entry name" value="Cas_DxTHG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02221">
        <property type="entry name" value="cas_TM1812"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL73729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="417" mass="47042" checksum="EB6A402BCF285284" modified="2016-01-20" version="1">MKLLTFLGAGKYQPTRYIYQGQDCLTSFSPIASCAFLRPTQVIVFVTDEVKTKTLPEFLKEVPAGTEVITREIPIGADEQQLWQIFDALAGSVSPGEEVAFDITNGFRSFPLLGLLAAAFLRSGFNVNLRAVLYGAFDASRLVSPDETPMIDLTPMLTLLEWSSAADRFNRTGDARYLASLIRQQRRALGIAAKNDPQRKNEAGRLGNLAGALEDVSHSLRLIRPFQTMRSTSGLSERVQAAMPALQGSAASQPFLMLLESIQNTYTPLGMSDPLDPAQAQQSIGKQREIIQWYAEREQWVQAATLAREWMVNWIMFQMQLFDICERDDRRRIEEVINSESHQYKTACQKKEPFRSLFLRQVPQVEEALELWNILADTRNDINHAGMRRDPGAPDDLIKQLQKIIERINRLPLEHGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XP74</accession>
    <name>A0A0P6XP74_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_06725</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Fur family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000018">
        <property type="protein sequence ID" value="KPL78415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062213.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000018.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78415">
        <property type="protein sequence ID" value="KPL78415"/>
        <property type="gene ID" value="ADN00_06725"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07153">
        <property type="entry name" value="Fur_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002481">
        <property type="entry name" value="FUR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043135">
        <property type="entry name" value="Fur_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33202">
        <property type="entry name" value="PTHR33202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01475">
        <property type="entry name" value="FUR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="126" mass="14173" checksum="ED1B55137100B346" modified="2016-01-20" version="1">MRTSSVDQVILDVLAEEHHHLTAQQVYEHIRERMPAVNPSTIYRSLERLASEGKISVSDMGQGATVFESLADGMHHHLVCQSCGKCITVDHQLVGQFFAQVEKQLEFQVLTNHLILFGICKECQAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XP94</accession>
    <name>A0A0P6XP94_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_17835</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LytR/CpsA/Psr (LCP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000043">
        <property type="protein sequence ID" value="KPL70896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064397.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000043.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17835"/>
    <dbReference type="EnsemblBacteria" id="KPL70896">
        <property type="protein sequence ID" value="KPL70896"/>
        <property type="gene ID" value="ADN00_17835"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027381">
        <property type="entry name" value="LytR/CpsA/Psr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004474">
        <property type="entry name" value="LytR_CpsA_psr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13399">
        <property type="entry name" value="LytR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03816">
        <property type="entry name" value="LytR_cpsA_psr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00350">
        <property type="entry name" value="lytR_cpsA_psr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LytR_cpsA_psr" evidence="2">
        <location>
            <begin position="106"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="domain" description="LytR_C" evidence="3">
        <location>
            <begin position="371"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL70896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="466" mass="50435" checksum="610444EAD86FECDA" modified="2016-01-20" version="1">MKRKPRQLDRLTIILLAAFGVVALITAVLAFVVVRNLVNSWEMTDLPGSPQINAADPNLPATSGDASIPMQAAEGPIAEPWDGASRISVLVMGLDYRDWESGETPRTDTMILLTLDPTTRTAGMLSIPRDMWVEIPDFDHGKINTAYYLGEIYDIPGGGPALAMETVEGFLGVPIKYYAQVDFSAFVRFIDEIGGLKINVPEEIKVDPIGPGNTVILEPGVQILPGDVTLAYARARYTEGGDFDRASRQQQVIMAARDQILSLNMLPTLITKAPKLYAEISSGISTNLSLDQVIKLANLALQVDPNNIKRGIIGPDVVMNSKSPDGLDILIPIPDEIRMLRDEIFADSGSAMPIAALTDDPANLVQQEAARISLQNGSQTVGLAANTAEYLRGQGLNIVEETNADSIYDASAIIVYNGKPYTVQYLADMMGVTTANIYNRYDPNAPVDIAVILGNSWASNYSNLPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XPV0</accession>
    <name>A0A0P6XPV0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05595</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78717.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061987.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78717">
        <property type="protein sequence ID" value="KPL78717"/>
        <property type="gene ID" value="ADN00_05595"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="61"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="174"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="236"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78717.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="278" mass="32468" checksum="77AF91D3A402E361" modified="2016-01-20" version="1">MPHPKPSLPRRVARFFRWNRTSYMMMSAFLALIFLIGYVWWPLLEAYIQTYDPRVSFWQQFDWLLLGNFLVMSLLIMADANLRKDLPIAFIGLMGGLVIESWGTQTELWVYYTNERPPLWIIPAWPIASLSIDRLYRLLRSKLENVPLGVFRTLHWILLPAFLGYMLFFVWPTLDKSLTIMALILCAFLILTPTDPKAIVLTFVAGSGLGYFLELWGTTRWCWTYYTLQTPPFFAVLAHGMAAVAFWRVLELYQLFLPKIVARFKQRANPLSLPTELE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQ48</accession>
    <name>A0A0P6XQ48_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_06550</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062160.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06550"/>
    <dbReference type="EnsemblBacteria" id="KPL78863">
        <property type="protein sequence ID" value="KPL78863"/>
        <property type="gene ID" value="ADN00_06550"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1814"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03220">
        <property type="entry name" value="ABC_KpsT_Wzt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015860">
        <property type="entry name" value="ABC_transpr_TagH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="24"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="65"/>
            <end position="72"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL78863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="251" mass="28116" checksum="47E4C86D67864655" modified="2016-01-20" version="1">MNAYINLEDVSLKFRIYRNPTPSLKESFINKVFKKDHRVDEVLEFYALKNISLNIKGGDRLGIVGLNGAGKSTMLKTIAGIYTPHQGRISMAGQVTPLMELGAGFHPEQTGRDNIYLNGALLGHSVKDMQKREKAIIEFSELGEFIDLPVKYYSSGMYIRLAFSIATMTEPDILIMDEILSAGDAHFKQKASEKIKQLINVSQIVVLVSHNLQQIEEICNHAIVLHKGEMVNQGDPKEMVSYYLTEIAKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQI1</accession>
    <name>A0A0P6XQI1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_03870</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061650.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03870"/>
    <dbReference type="EnsemblBacteria" id="KPL79037">
        <property type="protein sequence ID" value="KPL79037"/>
        <property type="gene ID" value="ADN00_03870"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="535" mass="57697" checksum="0A34BC3A9E798FF5" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQL6</accession>
    <name>A0A0P6XQL6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">AP endonuclease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_04225</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061711.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79083">
        <property type="protein sequence ID" value="KPL79083"/>
        <property type="gene ID" value="ADN00_04225"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.202"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="1">
        <location>
            <begin position="22"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="334" mass="37817" checksum="70756833A1F60F57" modified="2016-01-20" version="1">MSRPIILTTGQWGDMPLETLAQKLSSWGYDGVELGSGGDHFDVEACLSSDRYAREKKDLLEKYGLKCYAISNHCVGQCICDDILDERHQAIIPASVWGDGKTEGVQRRAAEHMMNAARAARLMGVDVITAFTGSSIWRKLYFWPPTSDSVIDAGYRDFAERFTPIFDVFAQEKVKFALEVHPTEIAYDIYTMQRSLEAVNYHPAFGINFDPSHLVHQLINPVKLIEAFPERIFHMHIKDSKVRLDGSNSILSSHLNFGDHRRGWDFVSPGHGDVDWEHVFRTLNRINYQGAMSIEWEDSGMDREWGAQDALAMVKRINFPPSGQAFDSAFSHKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XSC4</accession>
    <name>A0A0P6XSC4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH cro/C1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_12825</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063416.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000027.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL75521">
        <property type="protein sequence ID" value="KPL75521"/>
        <property type="gene ID" value="ADN00_12825"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="44"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL75521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="137" mass="15334" checksum="E2233997E38E803D" modified="2016-01-20" version="1">MEKPIAQAQREAKNKTIDLGPFIARLTELMEKHNESYREAGMSAGLDHQAIRRILSGQRPAMVNCILLADHYGVNPNEFLELAGWPTLKVFDVRGLETDRLPPEAVDVALVLSRVPDPGVRKQLATAVITLLQKYFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XSH0</accession>
    <name>A0A0P6XSH0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_02415</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000010">
        <property type="protein sequence ID" value="KPL79668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061363.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000010.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79668">
        <property type="protein sequence ID" value="KPL79668"/>
        <property type="gene ID" value="ADN00_02415"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2699"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023811">
        <property type="entry name" value="CHP04076"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04076">
        <property type="entry name" value="TIGR04076"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="106" mass="11797" checksum="B05CF660066B6A58" modified="2016-01-20" version="1">MRQVKITVLKKHFYADLADAYLTEGKAVGPCPLLEEGDTFTYEGGAEMPPGFCPWAWIDIYRGVSALSAGATYTPWNNRDGMQILCCTDGIRPVIFAIEAIKEKEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XTN2</accession>
    <name>A0A0P6XTN2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_11505</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063158.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76573">
        <property type="protein sequence ID" value="KPL76573"/>
        <property type="gene ID" value="ADN00_11505"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="255" mass="28559" checksum="F85C5969F491E9E6" modified="2016-01-20" version="1">MRFVRNPEQTPEKILSPQQRKSAVYTILVIGLAIVALGTAGFFLSFILREQITQQGLNYRDTQTYSIAVAFAGVFIYAIAASVFKVGLRKTTFYKITTILKDEPFDPPMQGDHTKRILSELRYLSDEWAIFRDISPAGSKEAIPFVLCGPKGVYTLTVAAGRPGKKNFADPAPMLNHLTKSLSKDLNAEITPLILFMGNPVNYDTKSKAQALNINRIYRWVKEQPEQLNPAALEQMESKLFTLINPQKKSAPFIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XU54</accession>
    <name>A0A0P6XU54_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061914.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05200"/>
    <dbReference type="EnsemblBacteria" id="KPL78656">
        <property type="protein sequence ID" value="KPL78656"/>
        <property type="gene ID" value="ADN00_05200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018580">
        <property type="entry name" value="Uncharacterised_YfhO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38454">
        <property type="entry name" value="PTHR38454"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="190"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="236"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="267"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="298"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="327"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="363"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="392"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="422"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="445"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="717"/>
            <end position="739"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="750" mass="83039" checksum="5A4BC19327EBDD1C" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUG9</accession>
    <name>A0A0P6XUG9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Bifunctional protein GlmU</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="15">UDP-N-acetylglucosamine pyrophosphorylase</fullName>
                <ecNumber evidence="15">2.7.7.23</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="15">N-acetylglucosamine-1-phosphate uridyltransferase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="15">Glucosamine-1-phosphate N-acetyltransferase</fullName>
                <ecNumber evidence="15">2.3.1.157</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="15 17" type="primary">glmU</name>
        <name evidence="17" type="ORF">ADN00_10785</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C-terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N-acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5-triphosphate), a reaction catalyzed by the N-terminal domain.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>H(+) + N-acetyl-alpha-D-glucosamine 1-phosphate + UTP = diphosphate + UDP-N-acetyl-alpha-D-glucosamine</text>
            <dbReference type="Rhea" id="RHEA:13509"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
            <dbReference type="ChEBI" id="CHEBI:57776"/>
            <dbReference type="EC" id="2.7.7.23"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>acetyl-CoA + alpha-D-glucosamine 1-phosphate = CoA + H(+) + N-acetyl-alpha-D-glucosamine 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:13725"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57776"/>
            <dbReference type="ChEBI" id="CHEBI:58516"/>
            <dbReference type="EC" id="2.3.1.157"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="15">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="15">Bacterial outer membrane biogenesis; LPS lipid A biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="15">Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; N-acetyl-alpha-D-glucosamine 1-phosphate from alpha-D-glucosamine 6-phosphate (route II): step 2/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="15">Nucleotide-sugar biosynthesis; UDP-N-acetyl-alpha-D-glucosamine biosynthesis; UDP-N-acetyl-alpha-D-glucosamine from N-acetyl-alpha-D-glucosamine 1-phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Homotrimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 15">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">In the C-terminal section; belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 15">In the N-terminal section; belongs to the N-acetylglucosamine-1-phosphate uridyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.23" evidence="15"/>
    <dbReference type="EC" id="2.3.1.157" evidence="15"/>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063005.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10785"/>
    <dbReference type="EnsemblBacteria" id="KPL77039">
        <property type="protein sequence ID" value="KPL77039"/>
        <property type="gene ID" value="ADN00_10785"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2635"/>
    <dbReference type="UniPathway" id="UPA00113">
        <property type="reaction ID" value="UER00532"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00973"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019134">
        <property type="term" value="F:glucosamine-1-phosphate N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003977">
        <property type="term" value="F:UDP-N-acetylglucosamine diphosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000902">
        <property type="term" value="P:cell morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009245">
        <property type="term" value="P:lipid A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006048">
        <property type="term" value="P:UDP-N-acetylglucosamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03353">
        <property type="entry name" value="LbH_GlmU_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01631">
        <property type="entry name" value="GlmU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005882">
        <property type="entry name" value="Bifunctional_GlmU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038009">
        <property type="entry name" value="GlmU_C_LbH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025877">
        <property type="entry name" value="MobA-like_NTP_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12804">
        <property type="entry name" value="NTP_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01173">
        <property type="entry name" value="glmU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 15 17" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="10 15" id="KW-0133">Cell shape</keyword>
    <keyword evidence="14 15" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="4 15" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12 15" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="6 15" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11 15" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 15" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 15 17" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transf_3" evidence="16">
        <location>
            <begin position="5"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyrophosphorylase" evidence="15">
        <location>
            <begin position="1"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-GlcNAc binding" evidence="15">
        <location>
            <begin position="8"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-GlcNAc binding" evidence="15">
        <location>
            <begin position="77"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Linker" evidence="15">
        <location>
            <begin position="229"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="N-acetyltransferase" evidence="15">
        <location>
            <begin position="250"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Acetyl-CoA binding" evidence="15">
        <location>
            <begin position="384"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="15">
        <location>
            <position position="361"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="22"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="139"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="169"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="226"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="331"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="349"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="364"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="375"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-glucosamine</name>
            <dbReference type="ChEBI" id="CHEBI:57705"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="378"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="403"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="421"/>
        </location>
        <ligand>
            <name>acetyl-CoA</name>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF12804"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KPL77039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="452" mass="48094" checksum="45A1C46668E69567" modified="2016-01-20" version="1">MNVSAVILAAGQGTRMRSKLPKVLHPICGRPQIEYSLRAAAGAGAETIVVVVGHGAEQVREVVGERAVFALQEQQLGTAHALQSARSQVSGSAGLVLVISADMPLLTGETLSALVEAQRGSTGALSLLTVISDHPRGFGRVVRGPDGLVVAIVEERDCTPEQLAIRELNVAAYCFNEAWLWGALERVKKSPKGEYYLTDVVALAAQDGLKVNAIVLQDPAEAMGINTRVHLAEAEAVMRQRINQRHMLNGVTLIDPATTFIEDSVQIGMDTVVWPNTYLRGSTHIGEDCQIGPNTMMDDCQVGNRCKVLAAVMEKAVLEDDVDMGPFARLRKGAHLAQHVHMGNFGEVKDSYLGPGTKMGHFSYIGNAQIGPDVNIGAGTITCNYDGVKKHPTEIGANVFIGSDTMLVAPLKIGDNSKTGAGSVVTHDVPPDTVVVGVPARPLTKKTERHDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XV04</accession>
    <name>A0A0P6XV04_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">GlcNAc-PI de-N-acetylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_09130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062687.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09130"/>
    <dbReference type="EnsemblBacteria" id="KPL77286">
        <property type="protein sequence ID" value="KPL77286"/>
        <property type="gene ID" value="ADN00_09130"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4060"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003737">
        <property type="entry name" value="GlcNAc_PI_deacetylase-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024078">
        <property type="entry name" value="LmbE-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02585">
        <property type="entry name" value="PIG-L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102588">
        <property type="entry name" value="SSF102588"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL77286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="281" mass="31822" checksum="2C14670611393381" modified="2016-01-20" version="1">MFHQPTAEIYIPDQLPVEIALARTTHLCVAAHQDDIEIMAARPILECFQREDRWFTGVVVTDGRGSPRNGIYEKYDDEEMRLVRFKEQRKAAMVGEYAAQIMLDYPSRAVKDGANQSPVEDMVKLVQLTRPDVVYTHNLADKHDTHVGVALKLIAALRSLPSEERPRKLYGCEVWRSLDWMLDSDKVNFELSEQENLQAALLGVFDSQISGGKRYDLASLARRRANATYSESHGVDVSTGLSFAMDLSPLLTDLHLSPAAYVETYIQRFSSDVSQRIQRMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XV25</accession>
    <name>A0A0P6XV25_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_09300</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77313">
        <property type="protein sequence ID" value="KPL77313"/>
        <property type="gene ID" value="ADN00_09300"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007016">
        <property type="entry name" value="O-antigen_ligase-related"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04932">
        <property type="entry name" value="Wzy_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="50"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="113"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="136"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="158"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="244"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="283"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="310"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL77313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="337" mass="38115" checksum="02A0264DEC56F7EE" modified="2016-01-20" version="1">MASCIPAIFWSRSMISGVGQYIRIISPLIILFSMYQLVRSQRHIEITLKYMSLVTIATLTTMGLSLFQGVPTVVLSGIQRITGSGLFVQQFAKFVALNIEILLLYFTTIKRKLTLPLSIGLSSLSIILFLTYHRTSWLILFISIIMGAILFRKERLYWVILFGGSIAAIIFHDELINIILRFITPSSLEDINRISSSRFLLYTLYLREFANADPIHWLFGMGYGDPNQITDTVIGTYLPPHNDYIAYLVEAGIITLILYFAILISVTIYSLKNNQSENPQIKSLSRHTTIIVTLMLLAGIPGAFYGNVMSSWYLFALIGVFFAGVRIRKAQHFEDKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XVB1</accession>
    <name>A0A0P6XVB1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Methylmalonyl-CoA mutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_04840</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>adenosylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061825.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04840"/>
    <dbReference type="EnsemblBacteria" id="KPL79177">
        <property type="protein sequence ID" value="KPL79177"/>
        <property type="gene ID" value="ADN00_04840"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.334"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006159">
        <property type="entry name" value="Acid_CoA_mut_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006158">
        <property type="entry name" value="Cobalamin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036724">
        <property type="entry name" value="Cobalamin-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02310">
        <property type="entry name" value="B12-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52242">
        <property type="entry name" value="SSF52242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00640">
        <property type="entry name" value="acid_CoA_mut_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51332">
        <property type="entry name" value="B12_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="B12-binding" evidence="3">
        <location>
            <begin position="5"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL79177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="136" mass="13958" checksum="751D7FBCFB34F5D2" modified="2016-01-20" version="1">MTERKIRVLVAKPGLDGHDRGAKVVAQALRDAGMEVIYTGLRQTPEMIAEAALQEDVDVVGLSILSGAHMALVPRVLDLLAANGQSDVRVFVGGIIPEADVAALRKMGVAAVYGPGAATGEIVADIQALFASAAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XVC4</accession>
    <name>A0A0P6XVC4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_04960</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061846.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04960"/>
    <dbReference type="EnsemblBacteria" id="KPL79196">
        <property type="protein sequence ID" value="KPL79196"/>
        <property type="gene ID" value="ADN00_04960"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.359"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031308">
        <property type="entry name" value="UCP028777"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005185">
        <property type="entry name" value="YccF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03733">
        <property type="entry name" value="YccF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028777">
        <property type="entry name" value="UCP028777"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="YccF" evidence="2">
        <location>
            <begin position="4"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="domain" description="YccF" evidence="2">
        <location>
            <begin position="70"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="122" mass="13107" checksum="7E09296A01D277E0" modified="2016-01-20" version="1">MSFLGNVIWLLFGGFVTGMGYILGGLAMCLTIIGIPFGVQSIKLGVAALTPFGREIVVTERASGFVAVVFDALWLILFGWEIALVHLGHALILAITIVGLPFAKQHLKLVPLALFPFGRELN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XWA2</accession>
    <name>A0A0P6XWA2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_14620</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000035">
        <property type="protein sequence ID" value="KPL73603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14620"/>
    <dbReference type="EnsemblBacteria" id="KPL73603">
        <property type="protein sequence ID" value="KPL73603"/>
        <property type="gene ID" value="ADN00_14620"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="SSF63411"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M16" evidence="1">
        <location>
            <begin position="18"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_C" evidence="2">
        <location>
            <begin position="171"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL73603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="418" mass="46024" checksum="A7D64E0086353BAE" modified="2016-01-20" version="1">MPGPDDVHRFVLENGIVVLCRQNLTSPSVQINGYLTYGSMFDPPEQLGLAQFTTLGLMKGTQKRSFSEIYDALESVGASLGLASSVHTTSFSGRALAEDLPLLLSILQESITQPTFPPDQIERLRAQYVTGLEIRDQSTEDMASMTFDQMLFPNHPYGLPVDGYANTVKAISRDDLVEFHRRHAGPRGMVIAIVSNLAPEEALHQVQDALGGWNNPEQIAEPSFPAVSAPTQTRREHVELAGKSQSDLVMGTLGPRRNDDDYVAASLGNNVLGQFGMFGRIGEVVREQSGLAYYASTHINASSEAGSWEVSAGVNPANLDRAIELIIGELRRFTREPVSLEELEDTQSYYLGRLPMQLESNAGVAGALINIERYQLGLDYYRRYPQMVLEVTPEKVLEAARRYIEPDKLYIATAGSRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XWN3</accession>
    <name>A0A0P6XWN3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_00095</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL80993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060923.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80993">
        <property type="protein sequence ID" value="KPL80993"/>
        <property type="gene ID" value="ADN00_00095"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="241"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="279"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="312"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="336"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="366"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="516" mass="57318" checksum="7FCC6995E9AF2026" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XX16</accession>
    <name>A0A0P6XX16_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RCK C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_00670</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061022.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00670"/>
    <dbReference type="EnsemblBacteria" id="KPL81076">
        <property type="protein sequence ID" value="KPL81076"/>
        <property type="gene ID" value="ADN00_00670"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044849">
        <property type="entry name" value="CASTOR/POLLUX/SYM8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010420">
        <property type="entry name" value="CASTOR/POLLUX/SYM8_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31563">
        <property type="entry name" value="PTHR31563"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06241">
        <property type="entry name" value="Castor_Poll_mid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="84"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="3">
        <location>
            <begin position="304"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL81076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="648" mass="69603" checksum="35A5C1602FBF4261" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XY76</accession>
    <name>A0A0P6XY76_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Fe/B12 periplasmic-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_00800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00800"/>
    <dbReference type="EnsemblBacteria" id="KPL81097">
        <property type="protein sequence ID" value="KPL81097"/>
        <property type="gene ID" value="ADN00_00800"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002491">
        <property type="entry name" value="ABC_transptr_periplasmic_BD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01497">
        <property type="entry name" value="Peripla_BP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50983">
        <property type="entry name" value="FE_B12_PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fe/B12 periplasmic-binding" evidence="1">
        <location>
            <begin position="1"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL81097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="232" mass="26813" checksum="782BFC71D54D3D6B" modified="2016-01-20" version="1">MNIEQVFSLHPDFVFGNPEENSQKDIEELQELGIPVVLQFPKTIEQALSDLWEIARLLKSQPAAARVDMLERSWEWFRASRVSEPKRRVFCPIWQSIDELAQPWWMVFNGDTYPGDVIRQFGGENIFETRQRLYPLEADLGLKKAEDPGLRDVRYPRVTLDEIVEGQPEIILLPSEPFAYSSGHISLFLKLFVDTPAGKSHRIRLVDGRLLTWHGTFLAHTLAELPEIFNIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y023</accession>
    <name>A0A0P6Y023_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_05330</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78676.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061938.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05330"/>
    <dbReference type="EnsemblBacteria" id="KPL78676">
        <property type="protein sequence ID" value="KPL78676"/>
        <property type="gene ID" value="ADN00_05330"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024478">
        <property type="entry name" value="HlyB_4HB_MCP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12729">
        <property type="entry name" value="4HB_MCP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0807">Transducer</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="13"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="192"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="6">
        <location>
            <begin position="261"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="5">
        <location>
            <begin position="358"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="632"/>
            <end position="659"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL78676.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="674" mass="71731" checksum="406EB6F2B0212493" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y0X3</accession>
    <name>A0A0P6Y0X3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_05250</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78868.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05250"/>
    <dbReference type="EnsemblBacteria" id="KPL78868">
        <property type="protein sequence ID" value="KPL78868"/>
        <property type="gene ID" value="ADN00_05250"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1524"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78868.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="289" mass="33122" checksum="FA7B2C525799C384" modified="2016-01-20" version="1">MVYNHQRSRLIGQPTRGKTARNRLRRSDVFLLLYAEELLRRQGEIYTQSFYVDLGYGAEAHTTLESAQRFRQINPALPVLGVEIDPARVATAKPYENAITQFRLGGFNIPLQPGESARIIRAFNVLRQYEEGQVAGAHYLLASQLVPGGLVLEGTSDPFGRVWVANLLRKRPLTGSETALEHEGIVFGTNFRWGFEPGIFQPVLPKNYIHRMRPGEAIHEFMEAWKEAARLSAPFKTFGLRHWFTASAHLLQQMGYAVELRDRYLRRGFLVWKFNQPKTLLPDKQLMEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y1B3</accession>
    <name>A0A0P6Y1B3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PglZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000028">
        <property type="protein sequence ID" value="KPL75312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13070"/>
    <dbReference type="EnsemblBacteria" id="KPL75312">
        <property type="protein sequence ID" value="KPL75312"/>
        <property type="gene ID" value="ADN00_13070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017850">
        <property type="entry name" value="Alkaline_phosphatase_core_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013973">
        <property type="entry name" value="PglZ_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08665">
        <property type="entry name" value="PglZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53649">
        <property type="entry name" value="SSF53649"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PglZ" evidence="1">
        <location>
            <begin position="354"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL75312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="623" mass="71259" checksum="400BB08C81BC9ECC" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y5I5</accession>
    <name>A0A0P6Y5I5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_01670</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061223.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01670"/>
    <dbReference type="EnsemblBacteria" id="KPL80577">
        <property type="protein sequence ID" value="KPL80577"/>
        <property type="gene ID" value="ADN00_01670"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039672">
        <property type="entry name" value="MFS_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001927">
        <property type="entry name" value="Na/Gal_symport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018043">
        <property type="entry name" value="Na/Gal_symport_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11328">
        <property type="entry name" value="PTHR11328"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00792">
        <property type="entry name" value="gph"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00872">
        <property type="entry name" value="NA_GALACTOSIDE_SYMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="42"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="111"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="182"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="231"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="268"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="295"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="322"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="364"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="407"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL80577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="453" mass="50417" checksum="24F607769BB2E39A" modified="2016-01-20" version="1">MRESTLPFKTKLLYGFGDIGFSLTTTILGAFFAIFLTDVVGLAPGVAAIAIFVGRSWDYINDPLIGHLTDRTRTRWGRRRPFLLFGALPFGLAFCLLWLRPPFESQVALAVYYALAYLLFDMAATFVYMPYYALTPELTSDYDERTSLTSFRMFFSIVGSLVAFTVPIMLVGGFNPENLERVAVMGAVFGAASVLPLLSVFFGTREREEYMHQEQPSLRDSFKAALQNRPFIFGAVIFLLTWVSVDILQATLLYFVKYILGREAQSDLIMAVIFVTAMISLPLWNYAAHHWDKRTAYISGISFWAVVQVVLITTGAATPLPLVIFLCVLAGIGVGAAHVLPWSILPDAIEWDEWKTGTRHEGMFYSLITLMQKVASSLAVPLILLLLEMTGYLPNSAVQPARALWGIRFAVGPIPALLLCGGLLFAALYPLKRQEYRDLVQDLEARRASAAPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y604</accession>
    <name>A0A0P6Y604_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminotransferase</fullName>
            <ecNumber evidence="1">2.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_01075</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.-" evidence="1"/>
    <dbReference type="EMBL" id="LGCL01000003">
        <property type="protein sequence ID" value="KPL80815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061115.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01075"/>
    <dbReference type="EnsemblBacteria" id="KPL80815">
        <property type="protein sequence ID" value="KPL80815"/>
        <property type="gene ID" value="ADN00_01075"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="2">
        <location>
            <begin position="49"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL80815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="373" mass="41571" checksum="9664007152E481D0" modified="2016-01-20" version="1">MSKQFIPFDLERFMSIWENQVDYNLSESGVHPLTMRELVQDPKVLDEILNTTLGYPQTNGSIELREKISAIYPGTTIDNVLVTTGAAQANFTSLWTLLAPGDEVAIMLPNYMQIWGIAQNLGMKVNTFSLKEESGWALDIDELNRAVTPNTKLIAVCNPDNPTGHIFTPAEMDAVVAAARRAGAWLLADEVYAGSEREGDSVTPSFWGRYEKVLAIGSMSKAYGLPGLRVGWVVSPAPTAQELWARQDYITIGTGMIDNKLAAYALSPDVRPRLLQRTRDYVRQGYQNFEDWASQHPGVFSWVPPQAAAIVFLRYHAPLNSSQLIENLIQVKRTYFVPGDHFGLDGHIRVSFGLSRQQLEEGLNRLNTLLQNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y6V5</accession>
    <name>A0A0P6Y6V5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PGA_cap domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_09310</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CapA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062718.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09310"/>
    <dbReference type="EnsemblBacteria" id="KPL77315">
        <property type="protein sequence ID" value="KPL77315"/>
        <property type="gene ID" value="ADN00_09310"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4095"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07381">
        <property type="entry name" value="MPP_CapA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019079">
        <property type="entry name" value="Capsule_synth_CapA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09587">
        <property type="entry name" value="PGA_cap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00854">
        <property type="entry name" value="PGA_cap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGA_cap" evidence="2">
        <location>
            <begin position="3"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="362" mass="41652" checksum="BD1B83AE4D93814C" modified="2016-01-20" version="1">MIKVLVAGDFCPLQDRNLLENWILDQQIFQDHDIRILNLEGPLTDNHNPILKIGPNLRIDPCWASVIAASGFNVVTLANNHILDMGEKGLIETIHHCDQSGIGHVGAGKNISDARKPLIMDMNGARIGFLAFTENEFSIASEACAGAAPIDPVANYYSIKEIREKLDYLILICHGGNELFKFPRPGMISLSRYYSDIGADAIIWHHSHVPCGYEIYNGTHIFYGTGNFYFPHKKHTFSDWYTGYLVSLELQKNKISSRIIPYKFDLQKISFLAGTELSNFTSDLEHLCDELLDTHKLQRRWKDHCYEKRKYYISTLIANSRCEKLLFRLDVLKEKYYAKKLRFLRNLIECESHRELLLELLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y851</accession>
    <name>A0A0P6Y851_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PGA_cap domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_08095</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CapA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77836.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08095"/>
    <dbReference type="EnsemblBacteria" id="KPL77836">
        <property type="protein sequence ID" value="KPL77836"/>
        <property type="gene ID" value="ADN00_08095"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019079">
        <property type="entry name" value="Capsule_synth_CapA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09587">
        <property type="entry name" value="PGA_cap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00854">
        <property type="entry name" value="PGA_cap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGA_cap" evidence="2">
        <location>
            <begin position="240"/>
            <end position="481"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77836.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="554" mass="60638" checksum="BA278BE8E76CDA65" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-08-12" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y8P4</accession>
    <name>A0A0P6Y8P4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HTH deoR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_07865</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000020">
        <property type="protein sequence ID" value="KPL78083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78083">
        <property type="protein sequence ID" value="KPL78083"/>
        <property type="gene ID" value="ADN00_07865"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001034">
        <property type="entry name" value="DeoR_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013196">
        <property type="entry name" value="HTH_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028349">
        <property type="entry name" value="PafC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026881">
        <property type="entry name" value="WYL_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08279">
        <property type="entry name" value="HTH_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13280">
        <property type="entry name" value="WYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016838">
        <property type="entry name" value="PafC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51000">
        <property type="entry name" value="HTH_DEOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH deoR-type" evidence="3">
        <location>
            <begin position="2"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL78083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="318" mass="36125" checksum="7DBDEE7C073DF1EB" modified="2016-01-20" version="1">MRADRLLSIILLLQTRGKMTAKALGEELEISRRTILRDINALSFSGVPVYSEGGHGGGFSLDEAYRTTLTGLNTKEVQSLFVSSNSEALRDVGLGDAGERLLLKLLAALPNPHHSTADHIRQRLMIDPTWWWHETSISPYWEEIQRAVYEDRMIHAQYENFDGKIAERTLAPYSLICKSSVWYLLAERDGELRTYRVNRFHSVQLLDGSFTRRPDFDLPAYWRAHTQNLENFSSGYHCTLRVHPERISFIKTLMPGRWEMAADAEDNGWKTISLSMDSDLQAKMLVFGLAGFVEVVEPGELKEAVAAQAREILEQLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y9A2</accession>
    <name>A0A0P6Y9A2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_07710</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062400.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78329">
        <property type="protein sequence ID" value="KPL78329"/>
        <property type="gene ID" value="ADN00_07710"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="268" mass="28582" checksum="838A411E69E7B763" modified="2016-01-20" version="1">MNEATPNKRLYLLLAGLAGALGIGLVVGAGLQALPARQTQVAAENTATAETRRFAWKTETPQVIELQITRMPSPTPRPAIEIVKSGWRVSSEGRARVFAVLRNNQPQAIDFTLVRATVLNSQGEVIGSGESYTLLDVTPPGSMNGAVIEIAVERGSIGEVVFEILPEEYRGEYIQDQIMVTGATVRLNAQGIPAAAVQVLNKAGEAVEKPLVAAALFDGSSHLVDIVTGSPEKGYWSPGEASEVWIGLPEEVAADVVRVEAWAQGYRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y9H5</accession>
    <name>A0A0P6Y9H5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NTP_transf_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_06765</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000018">
        <property type="protein sequence ID" value="KPL78421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062222.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000018.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06765"/>
    <dbReference type="EnsemblBacteria" id="KPL78421">
        <property type="protein sequence ID" value="KPL78421"/>
        <property type="gene ID" value="ADN00_06765"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002934">
        <property type="entry name" value="Polymerase_NTP_transf_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01909">
        <property type="entry name" value="NTP_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NTP_transf_2" evidence="1">
        <location>
            <begin position="13"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="277" mass="30599" checksum="879423BA8028375F" modified="2016-01-20" version="1">MQTNTRHLQLAQEIARRLEPFPAVQAVAVGGSLAGGHADETSDIDLYVFTTAEIPLAFRKAIIEELGASHADLDLRFWDPGDEWVHADTGIEVDMVYWDTAWISEQLERVLGQQQAGTGYTTCFWHTIRLIQPLFDRQGWLAALRDKAAQPYPPALRQEIIAKNMAVIRGCIPAYESQVNKALRRGDAVSVNHRLAALLASYFDALFAYNWLTHPGEKRLVEYALKHCRRAPAGMAAEINTVLRLAGDMRPELSGALAGLIDGLEACLASGELPPLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y9V3</accession>
    <name>A0A0P6Y9V3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_06600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000017">
        <property type="protein sequence ID" value="KPL78585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062187.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000017.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78585">
        <property type="protein sequence ID" value="KPL78585"/>
        <property type="gene ID" value="ADN00_06600"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2828"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="414" mass="44849" checksum="D80E1937B172BE68" modified="2016-01-20" version="1">MALNQKHYFSLAIRILGIVSLVGLLWFSQGERARLAAAAPLLPWQSTLPESVTINGRVTHGGGGELPAEMEVLLVVYEDMTVKMQQVTGVDADGYFEFLEVPVRSGWAYLVSVIHQEVPFYSDLITADDLAFVSEISLPVKIYDSTRDTSGLRAEAVQVSIDFSEPGMLRVAQSYTIANPSALVVLPAEADGAVLTFSLPANAQQVSLADGELGGRFIRAGDQVGDRQAVLHHERQHTVAYAYQVPYTRGYTLELILPVETRSLSVMAPANGVRLKGTGLNDAGTRDAQGQTMRLFTASNLPAGEVVKLEISGRPRDPGDPVSTSSLSIGLAGLALAVIASAVVVSRWTKHEPPAAEGTYLVGNGSDEPVEYWLEQIASLDDLQRSGQIDPAVYEARRAELKSRLHKIRQRDEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YBB2</accession>
    <name>A0A0P6YBB2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_05085</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061871.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05085"/>
    <dbReference type="EnsemblBacteria" id="KPL79216">
        <property type="protein sequence ID" value="KPL79216"/>
        <property type="gene ID" value="ADN00_05085"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022791">
        <property type="entry name" value="L-PG_synthase/AglD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03706">
        <property type="entry name" value="LPG_synthase_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00374">
        <property type="entry name" value="TIGR00374"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="38"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="111"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="155"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="219"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="246"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="299"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL79216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="335" mass="37826" checksum="D936020BFF141D11" modified="2016-01-20" version="1">MKKWQIWLGILISVIFLYIAVRGLHLEDVWETIQSARYFWLLPAVLVYFVGVWVRTWRWQYLLRPLKKIPNRVMFPVVNIGYLGNNIYPARAGEVLRAFVLRRREQVPVSASLATIIVERIFDGVVMLGFVFLNLGQLAHLQGTTGFVGNIQNLALWAGAAFAAALIVFLLAAMFPALAERLATFFIDRLVPARWREKMRGFALRFLSGLESLRSPWEALMIFLTSVLIWLIETVVYWLVMQAFAFNINFFALMLINGVVNLATMLPSAPGYIGIFEAPGIALLQAFGVAGGVAAGYTVVLHITLWLPITLVGAFYFLREGLKWGEKIPTLEQES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YFX7</accession>
    <name>A0A0P6YFX7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO</fullName>
            <ecNumber evidence="10">2.1.1.74</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Folate-dependent tRNA (uracil-5-)-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Folate-dependent tRNA(M-5-U54)-methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">gid</name>
        <name evidence="10" type="synonym">trmFO</name>
        <name evidence="12" type="ORF">ADN00_00930</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the folate-dependent formation of 5-methyl-uridine at position 54 (M-5-U54) in all tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H(+) + NADH + uridine(54) in tRNA = (6S)-5,6,7,8-tetrahydrofolate + 5-methyluridine(54) in tRNA + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:16873"/>
            <dbReference type="Rhea" id="RHEA-COMP:10167"/>
            <dbReference type="Rhea" id="RHEA-COMP:10193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74447"/>
            <dbReference type="EC" id="2.1.1.74"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H(+) + NADPH + uridine(54) in tRNA = (6S)-5,6,7,8-tetrahydrofolate + 5-methyluridine(54) in tRNA + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:62372"/>
            <dbReference type="Rhea" id="RHEA-COMP:10167"/>
            <dbReference type="Rhea" id="RHEA-COMP:10193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74447"/>
            <dbReference type="EC" id="2.1.1.74"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the MnmG family. TrmFO subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.74" evidence="10"/>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061071.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00930"/>
    <dbReference type="EnsemblBacteria" id="KPL81118">
        <property type="protein sequence ID" value="KPL81118"/>
        <property type="gene ID" value="ADN00_00930"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3584"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030698">
        <property type="term" value="F:5,10-methylenetetrahydrofolate-dependent tRNA (m5U54) methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047151">
        <property type="term" value="F:methylenetetrahydrofolate-tRNA-(uracil-5-)-methyltransferase (FADH2-oxidizing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01037">
        <property type="entry name" value="TrmFO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002218">
        <property type="entry name" value="MnmG-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040131">
        <property type="entry name" value="MnmG_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004417">
        <property type="entry name" value="TrmFO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11806">
        <property type="entry name" value="PTHR11806"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11806:SF2">
        <property type="entry name" value="PTHR11806:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01134">
        <property type="entry name" value="GIDA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00137">
        <property type="entry name" value="gid_trmFO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10" id="KW-0274">FAD</keyword>
    <keyword evidence="4 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 10 12" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9 10" id="KW-0520">NAD</keyword>
    <keyword evidence="8 10" id="KW-0521">NADP</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10 12" id="KW-0808">Transferase</keyword>
    <keyword evidence="6 10" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="GIDA" evidence="11">
        <location>
            <begin position="6"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="9"/>
            <end position="14"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF01134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KPL81118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="453" mass="49838" checksum="0CDB319B1BF2E515" modified="2016-01-20" version="1">MEKILNIVGGGLAGSEAAWQAAQRGVKVNLFEMRPFVQTGAHATADLAELICSNSLGSRLPDRANGVLSLELQRLNSLLLECATQTQIPAGGALAVGREAFSRLVTEKIVNHPNITLIREEVKTIAPGVTVIASGPLTSPALSAEIQNLAGMNSLFFFDALAPIVTGESIDMNIAFRASRYDRGVQADGDYINAPFTREQYDLFVSELIKAERIELKSFETQLETGVRAGLHPFFESCLPVEVIAQRGERALAFGPMRPVGLTNPHTNHRPYAVVQLRQDNLAGDLYNLVGFQTNLKFSEQERVFRLIPGLENAEFVRYGQMHRNTFIAAPLLLNAHLQFKTQPRLFFAGQITGVEGYLGNIATGLLAGMNAVRFLNDQPLLHPPTTTMLGALLNYITQAEIDHFQPMKANFGILPPLSIPSRNKRERAVAYADRALQDMQTWLTDHQLDVQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YFY9</accession>
    <name>A0A0P6YFY9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_00985</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061083.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL81127">
        <property type="protein sequence ID" value="KPL81127"/>
        <property type="gene ID" value="ADN00_00985"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL81127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="182" mass="20755" checksum="D4787F9050FA1A69" modified="2016-01-20" version="1">MYNNLSAQRYKIQPDEKVSNVIAYTNSGLFWGEIILKEQLRVSTWLRTAAAPDRVCMFNARMIQVQPNGKATPILFPELYIPTSEILVFHLVPPDSDPLDYDPSEPNRKMEPITVMTAHYRLDATIRIASITNLARFLDVVKEPFTALYNVEITCPIMPALGCMKVPYAIARQQTAIFTYRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GKM6</accession>
    <name>A0A0N8GKM6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_18955</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18955"/>
    <dbReference type="EnsemblBacteria" id="KPL70122">
        <property type="protein sequence ID" value="KPL70122"/>
        <property type="gene ID" value="ADN00_18955"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008841">
        <property type="entry name" value="Siphovirus-type_tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05709">
        <property type="entry name" value="Sipho_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="97" mass="11030" checksum="E305B03863A98811" modified="2016-01-20" version="1">MWTVYGPGENLKVVNFTTNQELEVGITLNQEDTLEIDTRLGYKAVKKGDGSNQFFRLSPESVLWPLQRGENQVQIELSNTNESSKVIVHYVERFLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GKN1</accession>
    <name>A0A0N8GKN1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_19230</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064658.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70162">
        <property type="protein sequence ID" value="KPL70162"/>
        <property type="gene ID" value="ADN00_19230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="78"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="323"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="336"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="374"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL70162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="392" mass="43433" checksum="CA513C25C11268F7" modified="2016-01-20" version="1">MLNNNTDETKPVEVNPSTNALPVDMPPAPGIEKPKRLKWILGGVAAVVILGMIGGLIGYQTAIQNRKRIAADQLTLVTTTQFELGIADFQAGRLETARRRFEYVIQADPKYPGAAEKLTEVMLAMATLSTPTTAPTPTMTVEPTPDFSGVEEMMQRAQDLLRNKQWDDALTVLDLMRKENINFRTVEVDGMYYIALRERGVQKIVNDGNLEGGIYDLARVEKFAPLDKEADGFRTFARFYLTGASFWKVDWPQVLVYFEQVYPALPNLRDLSGWTAQERYRIALVEFGNQLMLAGDYCKAKDQFEKALTFSVDDKVNQAFEKAKRECEGDKDETPQETQAVTPVPTQTTPVPTETTPVPTEETPVPTEVTPVPTEVTPEPTESSGGGDTSGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GLP8</accession>
    <name>A0A0N8GLP8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Ornithine aminotransferase</fullName>
            <ecNumber evidence="3">2.6.1.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Ornithine--oxo-acid aminotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rocD</name>
        <name evidence="7" type="ORF">ADN00_15025</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-ornithine: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.13" evidence="3"/>
    <dbReference type="EMBL" id="LGCL01000036">
        <property type="protein sequence ID" value="KPL73098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063851.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000036.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15025"/>
    <dbReference type="EnsemblBacteria" id="KPL73098">
        <property type="protein sequence ID" value="KPL73098"/>
        <property type="gene ID" value="ADN00_15025"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1869"/>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00358"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050155">
        <property type="term" value="F:ornithine(lysine) transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004587">
        <property type="term" value="F:ornithine-oxo-acid transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00610">
        <property type="entry name" value="OAT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005814">
        <property type="entry name" value="Aminotrans_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010164">
        <property type="entry name" value="Orn_aminotrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11986:SF18">
        <property type="entry name" value="PTHR11986:SF18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00202">
        <property type="entry name" value="Aminotran_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000521">
        <property type="entry name" value="Transaminase_4ab_Lys_Orn"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01885">
        <property type="entry name" value="Orn_aminotrans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00600">
        <property type="entry name" value="AA_TRANSFER_CLASS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4 6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00030587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL73098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="401" mass="44190" checksum="8AEA605C9D423972" modified="2016-01-20" version="1">MINSIDYIELEEKYGAHNYHPLDVVLERGEGVWVYDVEGNRYLDCLSAYSALNQGHVHPRILEAMMNQARQLTLTSRAFRNVQLPQLYKELSELTGYEMALPMNSGAEAVETALKIARKWAYAVKQIPKYQAEIIVAGNNFHGRTISVISFSTEELYKSDFGPFTPGFIAVEYGNPEALEQAITPHTAAVLIEPIQGEAGVIIPPAGYLAKVREICKRNRVLMIADEIQTGLGRTGRLFACDHESICPDMVILGKALSGGFYPVSAVIGDQDTIGLLRPGEHGSTFGGSPLAAAIARESLKVIVEENLIQNAETMGNYIVSELNKTTSDHVKEIRGKGLLIGIELKPEARGARRFCEVLKQEGLLAKETHENVIRIAPPLIIDRPTVDWAIGKILDVLQMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GLX7</accession>
    <name>A0A0N8GLX7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CRISPR system Cms protein Csm5</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">CRISPR type III A-associated protein Csm5</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_14255</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">This subunit might be involved in maturation of a crRNA intermediate to its mature form.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CRISPR-associated Csm5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000034">
        <property type="protein sequence ID" value="KPL73730.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063701.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000034.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14255"/>
    <dbReference type="EnsemblBacteria" id="KPL73730">
        <property type="protein sequence ID" value="KPL73730"/>
        <property type="gene ID" value="ADN00_14255"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010173">
        <property type="entry name" value="CRISPR-assoc_Csm5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005537">
        <property type="entry name" value="RAMP_III_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38007">
        <property type="entry name" value="PTHR38007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03787">
        <property type="entry name" value="RAMPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01899">
        <property type="entry name" value="cas_TM1807_csm5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="327"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031720"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL73730.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="371" mass="42189" checksum="2647E4B2D6632B07" modified="2016-01-20" version="1">MANYRLKLSTLSPVHIGAGQELRMGFDFMLYEKLTWRLNEDAILAAKEKQLQVVRDGRYPLPGQMLNEADFDNPRFFRYVLRGTPRSSKTDARLQACIKDPFDRPFIPGSSLKGALRTALAWTGWDEVKPRLDRSALNNSRQWAGQNLEHNLFGPNPNKDLLRALQVSDSFTEARPDDCLIVVNAQVVTPRASGSPIELEAIRPNQVFTGSLRVDDTLFSEAANRVLGFNNRKRWLEELLPRAQKHSLARIAELQEWFTHVDLEGADKIAAFYRQLQNANLGANQALVQVGWGSGWDGKTFWTHLKRDEGFFEAIVSQYRLNRAGNSRRQRGDAFPKSRRTAMSTKTDAQGRQVSRLSAPFGWMIIELEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMS2</accession>
    <name>A0A0N8GMS2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_12155</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063286.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12155"/>
    <dbReference type="EnsemblBacteria" id="KPL76090">
        <property type="protein sequence ID" value="KPL76090"/>
        <property type="gene ID" value="ADN00_12155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015689">
        <property type="term" value="P:molybdate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008995">
        <property type="entry name" value="Mo/tungstate-bd_C_term_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004606">
        <property type="entry name" value="Mop_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005116">
        <property type="entry name" value="Transp-assoc_OB_typ1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03459">
        <property type="entry name" value="TOBE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50331">
        <property type="entry name" value="SSF50331"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51866">
        <property type="entry name" value="MOP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 6" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="7">
        <location>
            <begin position="6"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="domain" description="Mop" evidence="8">
        <location>
            <begin position="295"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51866"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL76090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="360" mass="39230" checksum="92FAE376537DCFE7" modified="2016-01-20" version="1">MTDSILRVEEIIVRRGGQIALDAPALDVLDGETLALIGPNGAGKSTLLMVLAKLIEPDKGKLIFRGETVTRENALAYRRRIGIVMQDALLLDTSVEENVASGLRFRGTPQQVIHQRVEHWLERLGIIGLRKRRARGLSGGEAQRASLARALALEPDVLFLDEPFSALDAPTRERLLADFYGLLKETSMTTIFVTHDRDEALLLGDRVAVLLDAHIRQIGKPNQVFAVPTDPQIARFVGVETVIEGEVVGEKEGLAQVKTNGFVLEAVGEVRVGQAVLLCLRPEDVTLWHESHASPSSARNTLPGRVLQATPQGPLERVVVDCGFPVVALITRASAREMQIEKGLPVSISFKASAVHLIAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMX8</accession>
    <name>A0A0N8GMX8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_11280</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76538.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063116.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76538">
        <property type="protein sequence ID" value="KPL76538"/>
        <property type="gene ID" value="ADN00_11280"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="116"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL76538.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="644" mass="70116" checksum="8BB3FE80007BC877" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMY4</accession>
    <name>A0A0N8GMY4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_11365</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11365"/>
    <dbReference type="EnsemblBacteria" id="KPL76586">
        <property type="protein sequence ID" value="KPL76586"/>
        <property type="gene ID" value="ADN00_11365"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.973"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="169" mass="19360" checksum="65E040646D550FF6" modified="2016-01-20" version="1">MNAALLERLRQAYPLNWDGTHGFSHWRRVREIGLRLAEETRANPKVVELFAFTHDIQRLNDHRDPQHGPRASQFIREHLVEMLDLNSQEVALLCQACEQHTQGLTEADPTVQTCWDADRLDLMRVGIYPDPNLLCTAAARQPEMIAWAVSLSMESQGYGEGCPDRRLEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GN19</accession>
    <name>A0A0N8GN19_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hydrogenase nickel incorporation protein HypB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_09690</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062801.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09690"/>
    <dbReference type="EnsemblBacteria" id="KPL76866">
        <property type="protein sequence ID" value="KPL76866"/>
        <property type="gene ID" value="ADN00_09690"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2395"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051604">
        <property type="term" value="P:protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05390">
        <property type="entry name" value="HypB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004392">
        <property type="entry name" value="Hyd_mat_HypB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30134">
        <property type="entry name" value="PTHR30134"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00073">
        <property type="entry name" value="hypB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="cobW" evidence="2">
        <location>
            <begin position="36"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL76866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="223" mass="24785" checksum="183C88CD2693B91B" modified="2016-01-20" version="1">METFKVLKIKESVFEDNNRQAEAIRQDLKKNKTFLLNLMSSPGSGKTTTVVRTIEALKDELKIGVVEADADSDVDARTVSLTGAKVIQLHTGGMCHMDANMTRQGLVEMGSDGLDFVILENIGNLLCPADFDTGAVKSAMILSVPEGDDKPLKYPHMFEVVDVLLVNKIDAMDFFNFDLQAVTERVTRLNPHIRIIPISAKTGEGIAEWAEWVRAEVHQWKNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GN29</accession>
    <name>A0A0N8GN29_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_10170</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062892.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76946">
        <property type="protein sequence ID" value="KPL76946"/>
        <property type="gene ID" value="ADN00_10170"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="148" mass="16503" checksum="824EF8D2B564EFB6" modified="2016-01-20" version="1">MPLRPIADFLRYHARFFTGKVKISPRGQAALPGAPAGYRPFLTVARKSPTASPAAALRVTFRVHKVNFWQRTLLPYGSIPFFAGAPGFISKTYLVNPQQSSFCGLYQWESAQAAQTYIESYQGRFMRRNALPGSVSFEIQPIADKDEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GN32</accession>
    <name>A0A0N8GN32_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10335</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76970.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062923.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76970">
        <property type="protein sequence ID" value="KPL76970"/>
        <property type="gene ID" value="ADN00_10335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="166"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="211"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="239"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="359"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="393"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="418"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="447"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="491"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="559"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="594"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="619"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="644"/>
            <end position="663"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76970.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="673" mass="75302" checksum="8C7C99EC7A3B9AE5" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GND8</accession>
    <name>A0A0N8GND8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Chromate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_07995</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the chromate ion transporter (CHR) (TC 2.A.51) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062464.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07995"/>
    <dbReference type="EnsemblBacteria" id="KPL77818">
        <property type="protein sequence ID" value="KPL77818"/>
        <property type="gene ID" value="ADN00_07995"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.599"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015109">
        <property type="term" value="F:chromate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014047">
        <property type="entry name" value="Chr_Tranpt_l_chain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003370">
        <property type="entry name" value="Chromate_transpt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02417">
        <property type="entry name" value="Chromate_transp"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004810">
        <property type="entry name" value="ChrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00937">
        <property type="entry name" value="2A51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="154"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="219"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="260"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="287"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="345"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="368"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL77818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="386" mass="41499" checksum="B92BD0048E459460" modified="2016-01-20" version="1">MSKNLFPVKVAPAHWAEIASAFLWLGLTAFGGPAAHIGIMQDEFVRRRKWADDRQFLDLLSITNLIPGPNSTEMAMHIGYLRAGIPGSLLAGAGFIFPSMMMTMLFAWLYVQFGALPQINGVLYGIKPVVIAIIFNAFLSFAPKILNNWKLTAIGLAVMTLYLLGINELVLLAVGGIGFMLYRNWRKAASSIWLAALPDSFLPAVSLASKIPYTPQTLFFTFLKIGAVLYGSGYVLLAFLHSDFVQRLGWITDQQLLDAVAVGQVTPGPLSTAATFIGFLMDGIPGALLATLAFFLPAVLLVWVVNPLVPVLRSSPWTSSLLDGLNAASLGLMAAVILTLVPTSLPNLPAGFILAIAALFLVKWKVNATWLILAGGLAGWLLTSLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNJ6</accession>
    <name>A0A0N8GNJ6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">UDP-N-acetylenolpyruvoylglucosamine reductase</fullName>
            <ecNumber evidence="16">1.3.1.98</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">UDP-N-acetylmuramate dehydrogenase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="16" type="primary">murB</name>
        <name evidence="18" type="ORF">ADN00_07400</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 16">Cell wall formation.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 16">
            <text>NADP(+) + UDP-N-acetyl-alpha-D-muramate = H(+) + NADPH + UDP-N-acetyl-3-O-(1-carboxyvinyl)-alpha-D-glucosamine</text>
            <dbReference type="Rhea" id="RHEA:12248"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:68483"/>
            <dbReference type="ChEBI" id="CHEBI:70757"/>
            <dbReference type="EC" id="1.3.1.98"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 16">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5 16">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 16">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="16">Belongs to the MurB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.98" evidence="16"/>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78282.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062344.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07400"/>
    <dbReference type="EnsemblBacteria" id="KPL78282">
        <property type="protein sequence ID" value="KPL78282"/>
        <property type="gene ID" value="ADN00_07400"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3303"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008762">
        <property type="term" value="F:UDP-N-acetylmuramate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.78.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00037">
        <property type="entry name" value="MurB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003170">
        <property type="entry name" value="MurB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011601">
        <property type="entry name" value="MurB_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036635">
        <property type="entry name" value="MurB_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21071">
        <property type="entry name" value="PTHR21071"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02873">
        <property type="entry name" value="MurB_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56194">
        <property type="entry name" value="SSF56194"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00179">
        <property type="entry name" value="murB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="14 16" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="7 16" id="KW-0132">Cell division</keyword>
    <keyword evidence="11 16" id="KW-0133">Cell shape</keyword>
    <keyword evidence="15 16" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="6 16" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 16" id="KW-0274">FAD</keyword>
    <keyword evidence="8 16" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="10 16" id="KW-0521">NADP</keyword>
    <keyword evidence="13 16" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12 16" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="17">
        <location>
            <begin position="31"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="active site" evidence="16">
        <location>
            <position position="177"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="16">
        <location>
            <position position="228"/>
        </location>
    </feature>
    <feature type="active site" evidence="16">
        <location>
            <position position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003921"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KPL78282.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="308" mass="32677" checksum="D7577B74E259B227" modified="2016-01-20" version="1">MDETVLTNLKQLFGSRLKENAPVSAFCTAQTGGKADILLVVNSATELREAALRLWQANLPFRVLGAGSNVLIADKGYRGAVIINRAKAYQIHAEADPPYLWAESGANLGGLARQAAIQGLSGLEWAAPVPGTLGGAVYGNAGAHGGDMAGNLALADILHPSGEMTQWNASQMAYQYRSSALKRSAEKAVILSASLHLSRSTRQQVTALMTKNLEQRRRTQPPGASMGSMFKNPPGDYAGRLIEAAGLKGARVGGVQISPLHANFFVNTGSATAADIYQLIHQARQAVQERFGVLLDLEIELLGDFEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNT3</accession>
    <name>A0A0N8GNT3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_03545</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061587.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78978">
        <property type="protein sequence ID" value="KPL78978"/>
        <property type="gene ID" value="ADN00_03545"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="19"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="255" mass="27416" checksum="66941EDA3826E32C" modified="2016-01-20" version="1">MKSETVNLDFEARGSGTPVVLLHGFPFNRRIWEDVNALLDEDLRLILPDLRGHGRSPVGERTNTMGAMARDVAALLDRLGIEQVVVAGHSMGGYAALAFARLFPRRLLGLGLIASHPLADSAEKAASRQASAERLEREGLGFLAESMPAQLSDIAHLYPRMKEIILENSSAGAAAAQLGMAARGDETATLQGLKAPALIIAGRRDRVVSLETAEAASRMLVNGRLVVLDDAGHMPMLECPQETARAILELARRVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNU8</accession>
    <name>A0A0N8GNU8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Valine--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Valyl-tRNA synthetase</fullName>
            <shortName evidence="8">ValRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">valS</name>
        <name evidence="13" type="ORF">ADN00_04330</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-valine + tRNA(Val) = AMP + diphosphate + L-valyl-tRNA(Val)</text>
            <dbReference type="Rhea" id="RHEA:10704"/>
            <dbReference type="Rhea" id="RHEA-COMP:9672"/>
            <dbReference type="Rhea" id="RHEA-COMP:9708"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57762"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78537"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.9"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">The C-terminal coiled-coil domain is crucial for aminoacylation activity.</text>
    </comment>
    <comment type="domain">
        <text evidence="8">ValRS has two distinct active sites: one for aminoacylation and one for editing. The misactivated threonine is translocated from the active site to the editing site.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the class-I aminoacyl-tRNA synthetase family. ValS type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.9" evidence="8"/>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04330"/>
    <dbReference type="EnsemblBacteria" id="KPL79098">
        <property type="protein sequence ID" value="KPL79098"/>
        <property type="gene ID" value="ADN00_04330"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.223"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004832">
        <property type="term" value="F:valine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006438">
        <property type="term" value="P:valyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07962">
        <property type="entry name" value="Anticodon_Ia_Val"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.740.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02004">
        <property type="entry name" value="Val_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002300">
        <property type="entry name" value="aa-tRNA-synth_Ia"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033705">
        <property type="entry name" value="Anticodon_Ia_Val"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013155">
        <property type="entry name" value="M/V/L/I-tRNA-synth_anticd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010978">
        <property type="entry name" value="tRNA-bd_arm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037118">
        <property type="entry name" value="Val-tRNA_synth_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019499">
        <property type="entry name" value="Val-tRNA_synth_tRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009008">
        <property type="entry name" value="Val/Leu/Ile-tRNA-synth_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002303">
        <property type="entry name" value="Valyl-tRNA_ligase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11946">
        <property type="entry name" value="PTHR11946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08264">
        <property type="entry name" value="Anticodon_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00133">
        <property type="entry name" value="tRNA-synt_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10458">
        <property type="entry name" value="Val_tRNA-synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00986">
        <property type="entry name" value="TRNASYNTHVAL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46589">
        <property type="entry name" value="SSF46589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50677">
        <property type="entry name" value="SSF50677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00422">
        <property type="entry name" value="valS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1" evidence="10">
        <location>
            <begin position="23"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_1" evidence="11">
        <location>
            <begin position="620"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="domain" description="Val_tRNA-synt_C" evidence="12">
        <location>
            <begin position="841"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="839"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="8">
        <location>
            <begin position="58"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="8">
        <location>
            <begin position="538"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="541"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF10458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KPL79098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="904" mass="102813" checksum="9669928BFBA2F424" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNY6</accession>
    <name>A0A0N8GNY6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_02975</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000013">
        <property type="protein sequence ID" value="KPL79402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061467.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000013.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79402">
        <property type="protein sequence ID" value="KPL79402"/>
        <property type="gene ID" value="ADN00_02975"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="65" mass="7186" checksum="C7BED289D50EB678" modified="2016-01-20" version="1">MDNRPGCLSGLLKLFLLDKLFDWLQERFGFGRGCMGCGCGVILLVIFLLLAGSVIFGTNWLEIGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GPJ5</accession>
    <name>A0A0N8GPJ5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_00655</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL81074">
        <property type="protein sequence ID" value="KPL81074"/>
        <property type="gene ID" value="ADN00_00655"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL81074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="64" mass="6845" checksum="BAA85A53DC68F7C5" modified="2016-01-20" version="1">MSETLDKNVPYPLYSLVAILADYTALIRVRALAVISGVNGAAAWLECEGLAWPTLVAQRADLIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WK30</accession>
    <name>A0A0P6WK30_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glycos_transf_1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_18340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064500.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70024">
        <property type="protein sequence ID" value="KPL70024"/>
        <property type="gene ID" value="ADN00_18340"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="197"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="388" mass="44536" checksum="59AB6FD1909123CC" modified="2016-01-20" version="1">MSNVKINKPSIAILTTYIAPYRVSLFEELQKRVGKLRIFISTKMEPNRRWGIDWGRLDVVVQNTITIPKKWKHPHGFIETTYTQIPMDTLSLLIDYQPDVIVSVEFGLRTLFSVFYKIFHWRCKLIIWAAISSVTEKGRSRFRVLVRKILLQFCDGVYVNGKSGRAYLNSLGMDDQRIFDAPYATDVDVFKDISIFRTQENAYRLLFIGQLIERKGLSYLLRGLSCWLEKNQNKRIEMWIAGYGNQAGLLESENKAPNFEIKLLGEVPYDRLAEIYCQCGALVFPTLADEWGMVVNEAMASGCIVLGSLYSQAVEEMVVEGQNGWAFHPENTDEIENVLDKFFSKSVEQLNEMRVNAKARSLEYSPDKIADMMNIAIQSVLCVDNDEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WN54</accession>
    <name>A0A0P6WN54_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_17350</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71451.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064313.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17350"/>
    <dbReference type="EnsemblBacteria" id="KPL71451">
        <property type="protein sequence ID" value="KPL71451"/>
        <property type="gene ID" value="ADN00_17350"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.534"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="26"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="262"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="312"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="357"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="436"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="666"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="713"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="760"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="25"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="295"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="437"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="699"/>
            <end position="792"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL71451.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="800" mass="87973" checksum="B8AA5A828F1E5B0A" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WPL4</accession>
    <name>A0A0P6WPL4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DZANK-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_16065</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064058.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16065"/>
    <dbReference type="EnsemblBacteria" id="KPL72008">
        <property type="protein sequence ID" value="KPL72008"/>
        <property type="gene ID" value="ADN00_16065"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3648"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025874">
        <property type="entry name" value="DZR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12773">
        <property type="entry name" value="DZR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DZANK-type" evidence="4">
        <location>
            <begin position="166"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL72008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="215" mass="23555" checksum="0D2EA05DF2CD3249" modified="2016-01-20" version="1">MSDSIQFTRNYQDKSTNQGFQFEFFCDRCGNGYRTRFRPFAAGMVSDALDTASGLLGGLFSRAANVGNSVSSSAYERAHDAAFQEAAQELKPQFVQCPRCSSWVCKDRCWNEKRGLCKDCSPDLGVEMSAAQSSRSVEEVWAHAKMAEEDKKLAEGNWRETIRASCPECGAPQAVNAKFCPECGAKLKANAHCPECGAKLQPGAKFCTECGKKVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WSQ9</accession>
    <name>A0A0P6WSQ9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_18090</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL69983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL69983">
        <property type="protein sequence ID" value="KPL69983"/>
        <property type="gene ID" value="ADN00_18090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1500.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010368">
        <property type="entry name" value="Com_YlbF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023378">
        <property type="entry name" value="YheA/YmcA-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06133">
        <property type="entry name" value="Com_YlbF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158622">
        <property type="entry name" value="SSF158622"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL69983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="133" mass="14948" checksum="72BAD39A1D1D38F3" modified="2016-01-20" version="1">MEDRLNELEVSPRLVTMQAARQFAEAFSELAEYQSFERAFQALRNDSAAQKALEDFQKKQASLKALIMLNSLSDEERQELLHLQDLFYSKPTVMSYLQAQRELVAISQSLGDLISTEIGLDYGTSCRTGGCCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WVT1</accession>
    <name>A0A0P6WVT1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_18515</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064529.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18515"/>
    <dbReference type="EnsemblBacteria" id="KPL70051">
        <property type="protein sequence ID" value="KPL70051"/>
        <property type="gene ID" value="ADN00_18515"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3011"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="248"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="273"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="301"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="5"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL70051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="335" mass="37659" checksum="0D37911BDE52B711" modified="2016-01-20" version="1">MVFVSVIVPCYNEQTTIRLLLDAVYQQSYQRDQMEVIIADGMSTDGTRAQIQAFQAQHPDLLVKVVDNTRRIIPAALNRAIEAASGSVIVRLDAHSRPDREYVARSVADLEAGLGDNVGGVWMIQPGADTWVARSIAVAASHPLGVGDALYRFTDTASEVDTAPFGAFRRELVERIGFFDETLLTNEDYEFNTRIRLSGGRVWLDPQIRSEYFARKNYGDLAKQYWRYGYWKLRMLRRYPKTLRWRQALPPLFVLSLVGLAILALFWHVALQLLILEAGFYLGVLLTASVPLAARHRDPRFLIGVPAAVAVMHLCWGAGFLWSGIQSIFSQQVVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WVW6</accession>
    <name>A0A0P6WVW6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH cro/C1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_18765</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70087">
        <property type="protein sequence ID" value="KPL70087"/>
        <property type="gene ID" value="ADN00_18765"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13443">
        <property type="entry name" value="HTH_26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="25"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="131" mass="14662" checksum="5BA54791FE7834BA" modified="2016-01-20" version="1">MESGSLEKFKEWLDKSLDDRNWKYADLARFTGLDSAVISNIVNGRRGLGIDTAALIGDVLAVRPDFLLRLYGALPPIPKEENEIEQLAYRISKLPAEDQQIIDDLIQAMLSRRGIFTNEKNNISNTEAPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WX98</accession>
    <name>A0A0P6WX98_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_17815</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000043">
        <property type="protein sequence ID" value="KPL70892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70892">
        <property type="protein sequence ID" value="KPL70892"/>
        <property type="gene ID" value="ADN00_17815"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="100" mass="11564" checksum="2503981D73C6D29C" modified="2016-01-20" version="1">MFNGLFIALLFKFCAARIIVNLSEVSLPPSLLSSALPSDCNNFFTMSFWRHMRLIFNLNLPEAHIRAIISEHCGPFTLSIHFSQPRCIYLLQRKDSKLYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WXA1</accession>
    <name>A0A0P6WXA1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_17840</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000043">
        <property type="protein sequence ID" value="KPL70897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064398.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000043.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70897">
        <property type="protein sequence ID" value="KPL70897"/>
        <property type="gene ID" value="ADN00_17840"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="151"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL70897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="279" mass="29450" checksum="65669BAB5F69CEF6" modified="2016-01-20" version="1">MNQPRGPWYLFTGLVMGLAMGLVYAWLLEPAQFTDASPRALEPTEQAVYRSMIALGYQANKDFGRAAARLALLGDENPALALRNQAEMQLSAGGQAQDAQALVDLSMALQSMPATQTAQAATLAVSTPTPPAAFTPGTPEAAGTEGAQAETRAPATPQATFTPRPTAASSGWEDAPYVLLEQEALCDDDGAPRIEIEVRDAQGQPRGGVPVNITWASGSNTFYTGLHPQISSGYADFEMAENEVYSLRVGRAGEAVNDLKSEVCESGGAGGWRLVFGLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WY58</accession>
    <name>A0A0P6WY58_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_17515</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064342.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL71477">
        <property type="protein sequence ID" value="KPL71477"/>
        <property type="gene ID" value="ADN00_17515"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL71477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="338" mass="38446" checksum="4D1E3A1A2F4292F7" modified="2016-01-20" version="1">MISLQDLKKWLNHFDASSLGLQSREYLDQAADAQTPSVTRHVVIEKLLEHARVSLKPLEYAEANFMAGVIFAEKEGDYRQSQAAFERALAGFEGDEHRRAVALWAVGMMERKNLQAGAGYRSWQTAFEIFDSIAERHKLAGQAERLQLAPWYQERADRMQKEIALTAEHGYTLLDRFEPSPLDEITKALLRKAIKLTDGQQYASAYAVLRQVCKHSRLAEDYLNTPAGLLECGLVCYQAGFQEAACDFLHEAIEKYPPLSHRQAAAYWMYGCMLAGDLNHLGEIDLALTALQNALNIFSYLEKRSTDQNHKKKMIWYTQQHNLLEAAYQAALKDWISI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-04-07" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZ65</accession>
    <name>A0A0P6WZ65_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_16430</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064127.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72062">
        <property type="protein sequence ID" value="KPL72062"/>
        <property type="gene ID" value="ADN00_16430"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3728"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="8"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="146"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL72062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="216" mass="23562" checksum="666286CE40DD6BFC" modified="2016-01-20" version="1">MNLAEPIRILIVDDHAMVRSGLRMFLIVFDDLVLAGEASNGFEAISLVDQLNPDVVLMDLIMPGMDGIYASREILKNHPEIKIIALTSFSEAQLIHDALEAGVKGYLFKNATANELANAIRAVHAGNTIFSPEAAQMLSRVSAGTSEMVAINFTSREKEVLELMVAGCNNQEISDALTLSLSTTKFHVSNILTKMNVRSRGEAISMAIKHHLVTRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZK0</accession>
    <name>A0A0P6WZK0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_15600</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063958.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72241">
        <property type="protein sequence ID" value="KPL72241"/>
        <property type="gene ID" value="ADN00_15600"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="91" mass="10303" checksum="E4D11AF52D05C8EB" modified="2016-01-20" version="1">MRILLVEVENLKLAQEGRAIQNNWPKSPTSNGEFMTCFLDEVQIQLENINLENGNSEENQYRLWQALAYLQGVLDLVDGNTTPVPLDELVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-12-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZK4</accession>
    <name>A0A0P6WZK4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SH3b domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_15655</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063968.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72251">
        <property type="protein sequence ID" value="KPL72251"/>
        <property type="gene ID" value="ADN00_15655"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003796">
        <property type="term" value="F:lysozyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016998">
        <property type="term" value="P:cell wall macromolecule catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002053">
        <property type="entry name" value="Glyco_hydro_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003646">
        <property type="entry name" value="SH3-like_bac-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01183">
        <property type="entry name" value="Glyco_hydro_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08239">
        <property type="entry name" value="SH3_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00287">
        <property type="entry name" value="SH3b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51904">
        <property type="entry name" value="GLYCOSYL_HYDROL_F25_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51781">
        <property type="entry name" value="SH3B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SH3b" evidence="2">
        <location>
            <begin position="267"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL72251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="332" mass="37842" checksum="DF9A6F770A311A51" modified="2016-01-20" version="1">MLSSYVVDVSRYQKKILPALLRSKGVGAVIAKSSGSLSKDIKFDQHYTDCQKDEMPIAPYHWVDPIYYPEKQIDTFLSINKGRNIFAYVLDIEQWWNNWDAWYKAVIKQISWSAVPRIRPDLIAKHAKQCVDYLVSRADKSVILYTSYGFVTSYAQGMSEWLGDYSNWVANYVVQSNKKLTLEWEDLVYYLPYGKTPLLPPGVTLKNMVGWQFTGDLISLPGTYYDDRATILSPIDLNLFSKEWLEKATGKTMPTAPITMPEGKDVAVKYSVSPWVTLGLRMREGPDLNSQIITVLKAGSILDYAGKSKGMWKNVTWNDLSGWVHGSYIQKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X0H8</accession>
    <name>A0A0P6X0H8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">GtrA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_13610</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the GtrA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063573.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000032.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13610"/>
    <dbReference type="EnsemblBacteria" id="KPL74336">
        <property type="protein sequence ID" value="KPL74336"/>
        <property type="gene ID" value="ADN00_13610"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007267">
        <property type="entry name" value="GtrA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04138">
        <property type="entry name" value="GtrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="42"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="118"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="GtrA" evidence="7">
        <location>
            <begin position="14"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009399"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL74336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="153" mass="17369" checksum="2F1473FCD7ADA1A1" modified="2016-01-20" version="1">MILTKRNEQRRFFRFAIVGAIGAVVDFGLFNLLSAVLHVDTVVSSVISFVAAVLNNFLWNRYWTYPDSRSKSVSTQIIQFAAINVIGLLIRTPLFAFLESATVPVFEKMLPSNFFFSATFLGHNLSLATAILVVMMWNFFANRLWTYNDVKSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X334</accession>
    <name>A0A0P6X334_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_12780</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063409.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000027.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL75516">
        <property type="protein sequence ID" value="KPL75516"/>
        <property type="gene ID" value="ADN00_12780"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL75516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="91" mass="10134" checksum="D43ADEB3AC3FBC71" modified="2016-01-20" version="1">MSVHPLVAHQHTQEAMRLIERGECEVGFGLLLDLLKADPHNRCANRALVTLATRGELKFLQLGAFARAAPGFTRCGKFIRADWPGRKPRAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X4Z8</accession>
    <name>A0A0P6X4Z8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_09805</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062822.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09805"/>
    <dbReference type="EnsemblBacteria" id="KPL76887">
        <property type="protein sequence ID" value="KPL76887"/>
        <property type="gene ID" value="ADN00_09805"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001440">
        <property type="entry name" value="TPR_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013105">
        <property type="entry name" value="TPR_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00515">
        <property type="entry name" value="TPR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07719">
        <property type="entry name" value="TPR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="329"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="368"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="95"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="185"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL76887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="398" mass="44892" checksum="A3B7007C62A5BD4D" modified="2016-01-20" version="1">MNEQRRQQIQNNLTFKATDELLEIWQSGDASEWEAGVFDIIAEILQERLGALPPQSLETQALRLLREAGSLMEAGSDEQAIRQCESALHIHPEFALTHHTMGKIYENMGQPEQALIHFQKAIQLDYDFKDAWKNLLRVETQVQKQFESSLTKKQLDLALDDAREGEFDKAWQEIEAAKASLPGIAAAHNYLGLVLQSMGQLDAAIDAYASAILLNPRFSPARENLAQARAHWEEEQYHLFSTIALTDEQEASLASEEYLNAEVVESEEPLPGWYYLDEKACLITGWPGHRTGSGRSGYDPLKSDFELAHMQGLIFRKLIERKFRTRHPVYLLFMAVMGAIFISPLLGVVELFRGNLYVLPVILGYSPYWAAGIALLLNVVLSLLHVEDGNFEAGSLFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X588</accession>
    <name>A0A0P6X588_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alpha-amylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_10575</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062966.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77006">
        <property type="protein sequence ID" value="KPL77006"/>
        <property type="gene ID" value="ADN00_10575"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2586"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045857">
        <property type="entry name" value="O16G_dom_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aamy" evidence="2">
        <location>
            <begin position="8"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="327"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="452" mass="50868" checksum="E71678485E2A22E7" modified="2016-01-20" version="1">MNHWSYDAVFYHIYPLGLTGAPPRNDFASPSQPRLAALHGWLDHLQGLGVNALYLGPLFESSTHGYDSADYFHVDRRLGSDDTLRNLVNDCHARGMRVILDGVFNHTGRDFWAFRDVLHNRENSPYRDWFAGLRFNGNNPYGDGLRYDDWQGHASLVKLNLTNPRVVDHLLQAVESWIEQFDIDGLRLDAADCVDLGFQRALRAFTSQRRPDFWLMGEVVHGDYTRWANPQTLHAVTNYECYKGLYSSLNDQNYFEIAWSLNRQFGEQGLYGGLPLYNFVDNHDVNRAASVLKNPAHLYPLYLLLFTMPGVPSIYYGSEWGLSGEKTPSSDAALRPALPAPGEAAPPHPHLAKAISRLASLRHSSPALRRGDYQQLVVRHEQFAFLRSSPEESLVVALNAAQTPAEIEINLPAQPNGSLIDLLNPGERFPLRGGRAQMPLPAAWGRVLRVES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X597</accession>
    <name>A0A0P6X597_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_10680</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062985.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10680"/>
    <dbReference type="EnsemblBacteria" id="KPL77024">
        <property type="protein sequence ID" value="KPL77024"/>
        <property type="gene ID" value="ADN00_10680"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00865">
        <property type="entry name" value="PEBP_bact_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008914">
        <property type="entry name" value="PEBP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036610">
        <property type="entry name" value="PEBP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005247">
        <property type="entry name" value="YbhB_YbcL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30289">
        <property type="entry name" value="PTHR30289"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01161">
        <property type="entry name" value="PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49777">
        <property type="entry name" value="SSF49777"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00481">
        <property type="entry name" value="TIGR00481"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL77024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="158" mass="16927" checksum="0B92EDA1C047A0B3" modified="2016-01-20" version="1">MSQFNFQAEAFANGEMIPVQLTCDGKNVSPRLKWQGVPAGAKSLALIMEDPDSPMGVFVHWSLYNIEPTLTALPEALEKLTHLPGIGTQGLNDFDAVGYDGPCPSCGSSHHYTFDLYALDLPPQLPAALPGADLKKAIQGHIIASAHYTGEYARCGEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5Y4</accession>
    <name>A0A0P6X5Y4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HTH deoR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_09560</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062763.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77353">
        <property type="protein sequence ID" value="KPL77353"/>
        <property type="gene ID" value="ADN00_09560"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014036">
        <property type="entry name" value="DeoR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001034">
        <property type="entry name" value="DeoR_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018356">
        <property type="entry name" value="Tscrpt_reg_HTH_DeoR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00455">
        <property type="entry name" value="DeoRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08220">
        <property type="entry name" value="HTH_DeoR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00037">
        <property type="entry name" value="HTHLACR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00420">
        <property type="entry name" value="HTH_DEOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00894">
        <property type="entry name" value="HTH_DEOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51000">
        <property type="entry name" value="HTH_DEOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH deoR-type" evidence="4">
        <location>
            <begin position="3"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL77353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="257" mass="27975" checksum="1EB14B7062250F9B" modified="2016-01-20" version="1">MLATERQKTILEMLEKNKTVEVTELSECLSVSEMTIRRDLDKLEQAGLLTRTFGGAIVTSNPVALQLSFVEKVGVFEKEKQAIARAAASLIRDGDTVGLVAGTTCFQIAKNFPARENVTVVTNAINIAMEFANRGGIKLIVTSGYMLERSFALVGPFAECILEQIHINKLFLGATGISLDRGVTTQDLLEASMYKAMIRSAEQVIVVADHTKMGVVSLAPILPINKVNKLITDSEIDPLMLQKLEETGCEICVADID</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X6Z3</accession>
    <name>A0A0P6X6Z3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Flavodoxin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_06315</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062116.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06315"/>
    <dbReference type="EnsemblBacteria" id="KPL78829">
        <property type="protein sequence ID" value="KPL78829"/>
        <property type="gene ID" value="ADN00_06315"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026816">
        <property type="entry name" value="Flavodoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12724">
        <property type="entry name" value="Flavodoxin_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="1">
        <location>
            <begin position="54"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="214" mass="23166" checksum="59673C56E66EDC74" modified="2016-01-20" version="1">MSEPISRRNFLKKGLLIGAASGVVLCGGTSLVATYRPPLEKPTFSTESNGLNRILIAYATKAGTAAGIATHIGEQYANQGLAVDVMPVEQVNDLSAYATVIVGSGIYIGKIIPKAMDFIEKNQSALQNKSFHIFIACMTLREDTDENRKIVSDYLIPARAVVKPQSEGLFAGTINLSHLNLLEKMVVSSMQVPEGDYRNWPQIEAWAQAIPTAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X719</accession>
    <name>A0A0P6X719_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_12270</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76109">
        <property type="protein sequence ID" value="KPL76109"/>
        <property type="gene ID" value="ADN00_12270"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="111" mass="13201" checksum="EF82BDA0CC3E268D" modified="2016-01-20" version="1">MNQETIIFNLLFDLLFDLILELLIVVDLYYSILILFFHQERYLFAARLSFTLFRALPIKKSFKKKRLDYAATVYKRRMKIYSIFALIGGLLFSNILISEIIELIIQTRSII</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7B5</accession>
    <name>A0A0P6X7B5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Hydrolase_4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_03300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061538.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78939">
        <property type="protein sequence ID" value="KPL78939"/>
        <property type="gene ID" value="ADN00_03300"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydrolase_4" evidence="1">
        <location>
            <begin position="22"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="264" mass="29430" checksum="FD0BBC19731D58B1" modified="2016-01-20" version="1">MSSITTDQGILHYEVYGRGRPVILLHGWLGSWGLWRETMTYLGQSYRTYALDFWGFGESGRKRSTYKVQDFVSLVTQFMDQMGISSAPLVGHSMGGTVSLLAAIQSPERVQKVVIIGSPIVGSSLALALKLAGVPFNARALFTFFPLFRAVMRVASPFICSDPGFPDLMDRDLSRTTLESFLISIATLRKTDLRPQLNQIQVPVMGMFGDADNIVHPQQWKPLLAGVPHAQIERFPQAGHFIMLDEPPLFLDTLKKFLDQNPNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7D8</accession>
    <name>A0A0P6X7D8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N_BRCA1_IG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_08215</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062505.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77856">
        <property type="protein sequence ID" value="KPL77856"/>
        <property type="gene ID" value="ADN00_08215"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032350">
        <property type="entry name" value="N_BRCA1_central"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16158">
        <property type="entry name" value="N_BRCA1_IG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132887" description="N_BRCA1_IG domain-containing protein" evidence="1">
        <location>
            <begin position="30"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="N_BRCA1_IG" evidence="2">
        <location>
            <begin position="119"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="230" mass="24809" checksum="53617E4BF1F5BDFD" modified="2016-01-20" version="1">MSRYKKIIASALLLTTLAIVLTACGGGKAEPTLDANQVYTQAAETVQVQLTQTAAAMPTATQTSTPEPTLTPTVTEAVPTMALPGETTPQAGLPGTTQATTAPQQNLPDKATWVSNSPEDGTIKRPGEKFDLVWIMENTGTTTWTTSYQYRYYAGDRVHENVNSYFLPKEVKPGETVELRVDALAPDTPGSKYTLWVLTNAEGTNFGRMDFTWTVEGATLTPTATPEEDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7K7</accession>
    <name>A0A0P6X7K7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_03780</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061631.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03780"/>
    <dbReference type="EnsemblBacteria" id="KPL79021">
        <property type="protein sequence ID" value="KPL79021"/>
        <property type="gene ID" value="ADN00_03780"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003369">
        <property type="entry name" value="TatA/B/E"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02416">
        <property type="entry name" value="TatA_B_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0811">Translocation</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="63"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL79021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="100" mass="11448" checksum="AED0D056E67B20F6" modified="2016-01-20" version="1">MQLFNIGFLEIIFILLLAVVVLGPKDLAKTGRELGKFIRRVTRSDLWNSLQDTYYEVENLPRKLAEEAGADEMRREVEKIKQQAEGLFKEDESPPAADQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X8B0</accession>
    <name>A0A0P6X8B0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Translational regulator CsrA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">csrA</name>
        <name evidence="4" type="ORF">ADN00_17115</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">A translational regulator that binds mRNA to regulate translation initiation and/or mRNA stability. Usually binds in the 5'-UTR at or near the Shine-Dalgarno sequence preventing ribosome-binding, thus repressing translation. Its main target seems to be the major flagellin gene, while its function is anatagonized by FliW.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer; the beta-strands of each monomer intercalate to form a hydrophobic core, while the alpha-helices form wings that extend away from the core.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CsrA/RsmA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064268.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17115"/>
    <dbReference type="EnsemblBacteria" id="KPL71412">
        <property type="protein sequence ID" value="KPL71412"/>
        <property type="gene ID" value="ADN00_17115"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.485"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048027">
        <property type="term" value="F:mRNA 5'-UTR binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044781">
        <property type="term" value="P:bacterial-type flagellum organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006402">
        <property type="term" value="P:mRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045947">
        <property type="term" value="P:negative regulation of translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902208">
        <property type="term" value="P:regulation of bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006109">
        <property type="term" value="P:regulation of carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.4380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00167">
        <property type="entry name" value="CsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003751">
        <property type="entry name" value="CsrA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036107">
        <property type="entry name" value="CsrA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34984">
        <property type="entry name" value="PTHR34984"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02599">
        <property type="entry name" value="CsrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117130">
        <property type="entry name" value="SSF117130"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00202">
        <property type="entry name" value="csrA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1005">Bacterial flagellum biogenesis</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0810">Translation regulation</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="62"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL71412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="94" mass="10596" checksum="9B769D094CBC3A84" modified="2016-01-20" version="1">MLVLTRRKDESLMIGDDIVVTILGIEGDKVKIGIAAPQEIPILREEVYQAVVAQNKIKERLEQGPEPEAFKELRRMLSEAEPPPDAKTEEQKSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X8Y6</accession>
    <name>A0A0P6X8Y6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SWIM-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_02845</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000013">
        <property type="protein sequence ID" value="KPL79387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061447.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000013.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79387">
        <property type="protein sequence ID" value="KPL79387"/>
        <property type="gene ID" value="ADN00_02845"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2202"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007527">
        <property type="entry name" value="Znf_SWIM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04434">
        <property type="entry name" value="SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50966">
        <property type="entry name" value="ZF_SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SWIM-type" evidence="2">
        <location>
            <begin position="27"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="81" mass="9423" checksum="AAC9C118975FDF8E" modified="2016-01-20" version="1">MDYGMIGKIDKAKRYADERHRFHFHSFTVTVDGENNDHTVKYEDGKWNCDCSFFATRGRCSHTMALEFILEKMLADAPVES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9Z1</accession>
    <name>A0A0P6X9Z1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Ribose ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_06060</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062072.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06060"/>
    <dbReference type="EnsemblBacteria" id="KPL78880">
        <property type="protein sequence ID" value="KPL78880"/>
        <property type="gene ID" value="ADN00_06060"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1691"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="123"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="161"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="211"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="251"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="287"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL78880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="318" mass="33400" checksum="61C84F04848A2067" modified="2016-01-20" version="1">MNPSKSTQNIFEVLKSYSLYLAFLIIFIAFSLLNENFLSINNVLNIIVQSAIIAIIAVGQTMVILTSGIDLSVGSIVGAVGIGIGLLMVAGVSIPVAVVLGVIMGIVFGLINGVIISYGRVPAFITTLGMMGIARGFGLALNEGKPVAGLPQSFEKIASTSVAGIPSFVFYTLIIYVIMFFILERTKFGRHIYAIGGNRDAARLSGVKVKVVEMIVYLFSGLFSGLGAVLLTARLNYATPVAGTGYELDTIAAVVIGGTALSGGQGKIIGTLVGALMLGILRNGLTILNVSSFFQQIIIGAVIIIAVFMDKINEKKNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XA59</accession>
    <name>A0A0P6XA59_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_17525</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71479.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064344.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL71479">
        <property type="protein sequence ID" value="KPL71479"/>
        <property type="gene ID" value="ADN00_17525"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="18"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="92"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL71479.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="571" mass="65529" checksum="1AC90392766691F7" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAI3</accession>
    <name>A0A0P6XAI3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dihydroxyacetone kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_04510</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79127.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061763.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04510"/>
    <dbReference type="EnsemblBacteria" id="KPL79127">
        <property type="protein sequence ID" value="KPL79127"/>
        <property type="gene ID" value="ADN00_04510"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.259"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004371">
        <property type="term" value="F:glycerone kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006071">
        <property type="term" value="P:glycerol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012736">
        <property type="entry name" value="DhaK_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004006">
        <property type="entry name" value="DhaK_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02733">
        <property type="entry name" value="Dak1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02363">
        <property type="entry name" value="dhaK1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51481">
        <property type="entry name" value="DHAK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DhaK" evidence="1">
        <location>
            <begin position="7"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79127.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="333" mass="35737" checksum="5F15B1553417BB65" modified="2016-01-20" version="1">MKKLINKPEDVVVEELQGIALAHPDLVKVHFDPNYIVRADAPVKGKVGIISGGGSGHEPMHGGFVGKGMLDAACPGAVFTSPTPDQMLEATKAVDGGKGVLHIVKNYTGDVMNFEMAADLARAEGIEVESVLVDDDVAVQDSLWTAGRRGVGLTVVLEKIVGAAAEAGYSLKEVAELGRKINSLGRTMGMALTSCTVPHAGKPTFDLPEDEMEIGIGIHGEPGRKRMKLQPVDEIVEMLMEPILKDIPYKAGDEVILFVNGLGGTPLIEQYLVFRKAHEICEKNGIKVVRNLIGPYITSLEMAGTSITLLKVDEEMLKLWDAPVLTPGLRWGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAI4</accession>
    <name>A0A0P6XAI4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_15215</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063891.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15215"/>
    <dbReference type="EnsemblBacteria" id="KPL72180">
        <property type="protein sequence ID" value="KPL72180"/>
        <property type="gene ID" value="ADN00_15215"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.745"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025110">
        <property type="entry name" value="AMP-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_Synth/Lig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13193">
        <property type="entry name" value="AMP-binding_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="245"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding" evidence="2">
        <location>
            <begin position="31"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="domain" description="AMP-binding_C" evidence="3">
        <location>
            <begin position="466"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL72180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="560" mass="61715" checksum="A02FA41545C9184A" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAT7</accession>
    <name>A0A0P6XAT7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">2-oxoacid_dh domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09720</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062807.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76871">
        <property type="protein sequence ID" value="KPL76871"/>
        <property type="gene ID" value="ADN00_09720"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="2-oxoacid_dh" evidence="1">
        <location>
            <begin position="177"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="259" mass="29819" checksum="951B6373AA6B1D28" modified="2016-01-20" version="1">MNSKNDSRTVVPYLRERQLMVDGGQLGLQKHTIHGLVEFDITRARENIRQYRAQTGQALSFTAFFLFCLGKAIDADRNMHAYRDWRNQLVIFDDVDVNMLFEVEVDGQKAIRPHILRGINHKTPAELHQEMEAFQKGYQESRESKFIEWFVRLPQFARRMFLRVLFKNPQMVKELYGTVLLSSVGMFGRGSGWAIPVPNHTLQLTLGGMAEKPGVVQHRVEVREYLSVTISFDHDVVDGAPAARFMQRLKKLVESGVIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XB40</accession>
    <name>A0A0P6XB40_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4180 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_02895</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000013">
        <property type="protein sequence ID" value="KPL79392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061455.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000013.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79392">
        <property type="protein sequence ID" value="KPL79392"/>
        <property type="gene ID" value="ADN00_02895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025438">
        <property type="entry name" value="DUF4180"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13788">
        <property type="entry name" value="DUF4180"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4180" evidence="1">
        <location>
            <begin position="14"/>
            <end position="117"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="119" mass="13365" checksum="1B1CFC5B6BE01D42" modified="2016-01-20" version="1">MNYQVGQRGLIQWVELLPHQALITSENDALDWVGVCGELRALRLLVHESNLPEAFFDLRSGLAGGVLLKFSNYRMRVAAVVSAERASQGRFGEMVQETNRGSQFRVFQDATAAREWLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XC87</accession>
    <name>A0A0P6XC87_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_02050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000008">
        <property type="protein sequence ID" value="KPL79923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061301.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000008.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02050"/>
    <dbReference type="EnsemblBacteria" id="KPL79923">
        <property type="protein sequence ID" value="KPL79923"/>
        <property type="gene ID" value="ADN00_02050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2840"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="358" mass="39824" checksum="C21393BB398198BA" modified="2016-01-20" version="1">MQDSDSPILQTQVAVVGGGPIGIELAVALQLAGVDYRLFEAQQIGDTIARWPRNTHFFSTPERIAISGVPLNIPDQQNPTGEQYLAYLRGVISAFNVRVNNYERVESIEKISGGFTLRTQTLTGRRDWHCETVILATGGMAHPRWLRIPGEDLPHVSHGLDDPHRYFQRSVLVVGGRNSAIESAMRCWRAGANVCLSYYREELPRPHIKPSLRDDIDTVLRENQMRFIPASVPMEIHPGYVILARTRDGVPQFGDTLRVDCDFVLLATGFEADMSLFEQLGVTLQGENGAPLYEPSTMKTNVEGVYVAGTAAGGTQTRFEHFIETSHVHVDRILRALTGQPAQRVGYIVEKPDDNIIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XCE4</accession>
    <name>A0A0P6XCE4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DNA mismatch repair protein MutS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">mutS</name>
        <name evidence="10" type="ORF">ADN00_08510</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">This protein is involved in the repair of mismatches in DNA. It is possible that it carries out the mismatch recognition step. This protein has a weak ATPase activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the DNA mismatch repair MutS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062559.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08510"/>
    <dbReference type="EnsemblBacteria" id="KPL77901">
        <property type="protein sequence ID" value="KPL77901"/>
        <property type="gene ID" value="ADN00_08510"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.705"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1170.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00096">
        <property type="entry name" value="MutS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005748">
        <property type="entry name" value="DNA_mismatch_repair_MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007695">
        <property type="entry name" value="DNA_mismatch_repair_MutS-lik_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017261">
        <property type="entry name" value="DNA_mismatch_repair_MutS/MSH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007861">
        <property type="entry name" value="DNA_mismatch_repair_MutS_clamp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007696">
        <property type="entry name" value="DNA_mismatch_repair_MutS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016151">
        <property type="entry name" value="DNA_mismatch_repair_MutS_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007860">
        <property type="entry name" value="DNA_mmatch_repair_MutS_con_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036678">
        <property type="entry name" value="MutS_con_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS_family"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="PTHR11361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01624">
        <property type="entry name" value="MutS_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05188">
        <property type="entry name" value="MutS_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05192">
        <property type="entry name" value="MutS_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05190">
        <property type="entry name" value="MutS_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037677">
        <property type="entry name" value="DNA_mis_repair_Msh6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00533">
        <property type="entry name" value="MUTSd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="SSF48334"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53150">
        <property type="entry name" value="SSF53150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55271">
        <property type="entry name" value="SSF55271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01070">
        <property type="entry name" value="mutS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00486">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 7 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 7 8" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 7 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2 7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_MISMATCH_REPAIR_2" evidence="9">
        <location>
            <begin position="688"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="614"/>
            <end position="621"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00096"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL77901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="857" mass="95428" checksum="C056D4026DF73CA6" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDR3</accession>
    <name>A0A0P6XDR3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_00350</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060967.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00350"/>
    <dbReference type="EnsemblBacteria" id="KPL81029">
        <property type="protein sequence ID" value="KPL81029"/>
        <property type="gene ID" value="ADN00_00350"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003916">
        <property type="term" value="F:DNA topoisomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006265">
        <property type="term" value="P:DNA topological change"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006691">
        <property type="entry name" value="GyrA/parC_rep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035516">
        <property type="entry name" value="Gyrase/topoIV_suA_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03989">
        <property type="entry name" value="DNA_gyraseA_C"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101904">
        <property type="entry name" value="SSF101904"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL81029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="346" mass="37673" checksum="C28E6B71FDB89CE8" modified="2016-01-20" version="1">MERPPIDHIPVDVIQYIEYLESELARLKGKRDQRATTVLEDKADLSPVDYKEPPTSFNLVTFSQKGAVKRTNRGEYTRQRRGGIGVFDIETDQNDHPTLVVIADEPHTLILFSDHAKAYRLPVTKLEAHQIRSKGEYLSSKINLTPGETITAALPEQAAGYIALISKSGKVRCLRHHLFGEHMKPGTAMYKFEDFGPLASVCWTTGDADLFVVTRNGMGIRFSEKIVNPQGTQAIKLSDGDEVVSVVSVNEDDGVLVIGADGKGTIRLMSGFAPNKSAGGSGKIVIKSDKVAGALLAEADADIFLISKLSKIIRFHISDVPETTGVVQGVNCMSLRADEVIAIAKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XEP4</accession>
    <name>A0A0P6XEP4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4388 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05175</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061909.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05175"/>
    <dbReference type="EnsemblBacteria" id="KPL78651">
        <property type="protein sequence ID" value="KPL78651"/>
        <property type="gene ID" value="ADN00_05175"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025497">
        <property type="entry name" value="DUF4388"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14332">
        <property type="entry name" value="DUF4388"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4388" evidence="1">
        <location>
            <begin position="8"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="263" mass="29983" checksum="74DC4F3B1777EBD9" modified="2016-01-20" version="1">MVASVVTGSLYKKSLDQLLDLIELAQKTGKLHFSGYAEPLSVYFQDGRVTYSQIGKEKAAMYAVVVSCAKLLEGRLNLLRLKRELSDVAFSLHLMDRFGVSREEILQYVTRYYAETVVNGVFWRRRTFEFFEGEQPPEDVVTTRLRTGDVVRQAQKMVVEVDHIVSNLPSGMQSIICKTDLAQVEEAQTGIGYYEWKALHFIDNQRDIIQLSDAIRMERTELIRIIYNLSSMGLVNIYSADKSTYISPGAKTRVLSERSLFRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XF89</accession>
    <name>A0A0P6XF89_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Chaperonin GroEL</fullName>
            <ecNumber evidence="6">5.6.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">60 kDa chaperonin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Chaperonin-60</fullName>
            <shortName evidence="6">Cpn60</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 9" type="primary">groEL</name>
        <name evidence="6" type="synonym">groL</name>
        <name evidence="9" type="ORF">ADN00_07640</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 8">Together with its co-chaperonin GroES, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6 8">Forms a cylinder of 14 subunits composed of two heptameric rings stacked back-to-back. Interacts with the co-chaperonin GroES.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the chaperonin (HSP60) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.1.7" evidence="6"/>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062386.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07640"/>
    <dbReference type="EnsemblBacteria" id="KPL78316">
        <property type="protein sequence ID" value="KPL78316"/>
        <property type="gene ID" value="ADN00_07640"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3358"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042026">
        <property type="term" value="P:protein refolding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03344">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.7.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00600">
        <property type="entry name" value="CH60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018370">
        <property type="entry name" value="Chaperonin_Cpn60_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001844">
        <property type="entry name" value="Cpn60/GroEL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002423">
        <property type="entry name" value="Cpn60/GroEL/TCP-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027409">
        <property type="entry name" value="GroEL-like_apical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027413">
        <property type="entry name" value="GROEL-like_equatorial_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027410">
        <property type="entry name" value="TCP-1-like_intermed_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00118">
        <property type="entry name" value="Cpn60_TCP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00298">
        <property type="entry name" value="CHAPERONIN60"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48592">
        <property type="entry name" value="SSF48592"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52029">
        <property type="entry name" value="SSF52029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54849">
        <property type="entry name" value="SSF54849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02348">
        <property type="entry name" value="GroEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00296">
        <property type="entry name" value="CHAPERONINS_CPN60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="29"/>
            <end position="32"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="86"/>
            <end position="90"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="414"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="483"/>
            <end position="485"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="499"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL78316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="543" mass="58246" checksum="CF04993E48F0B238" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XFR5</accession>
    <name>A0A0P6XFR5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Response regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_03800</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061635.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03800"/>
    <dbReference type="EnsemblBacteria" id="KPL79025">
        <property type="protein sequence ID" value="KPL79025"/>
        <property type="gene ID" value="ADN00_03800"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="22"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="138" mass="15114" checksum="58A394ECFA0B1BB6" modified="2016-01-20" version="1">MPFVISNSPGSFRFALQGTALRVLIADPQRRVRAALKTLLSHQSGIQVVADTAAYENLHHLIQVCQPELLLIDPAIADQPFETVLHHLREAYPWLCIVAMSGKAELQPRALAAGANRFVSKADPPDRLLNAILPNHPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XFV9</accession>
    <name>A0A0P6XFV9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13930</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13930"/>
    <dbReference type="EnsemblBacteria" id="KPL74100">
        <property type="protein sequence ID" value="KPL74100"/>
        <property type="gene ID" value="ADN00_13930"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="381"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="408" mass="45579" checksum="A8A43853B04392FA" modified="2016-01-20" version="1">MSESLEAWRVNPLARRIVELTTQYVVGGGLAVSAKDAAAQQFLKAFWRSRLNRMETRCMEWCDELARSGNLFVLLSTDAAGMSYARAVPAASIQRIETRSNDSEQAVAFYPYPGLEQPDPRPWKAYDPQQDAPLAGGGFESVMLHYAVNRPVGAVWGESDLAPLLRWLARYANWLEDRARLNRYRNAFLYVVKARFASEAERIARQQQLNAQPPRPGSILVTGESESWEVLSPKLDANEANSDGLALKKMAAAGAGVPMHFLAEPEGSTRTTAEAAGGPTYRRFEQRQRFFLWVIEDVLRAALRRRAMLDRALDAEAEMEVRGADISARDNAALGLAAANINTVLAELRDRGLIDDGEYLRLVYRFAGEAVDAQSLLERARRAAPPRKPQVDRRRPPRQVLKPAEKLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XG61</accession>
    <name>A0A0P6XG61_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF3298 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_04755</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061809.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04755"/>
    <dbReference type="EnsemblBacteria" id="KPL79163">
        <property type="protein sequence ID" value="KPL79163"/>
        <property type="gene ID" value="ADN00_04755"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.640.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021729">
        <property type="entry name" value="DUF3298"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037126">
        <property type="entry name" value="PdaC/RsiV-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11738">
        <property type="entry name" value="DUF3298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133044" description="DUF3298 domain-containing protein" evidence="2">
        <location>
            <begin position="28"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3298" evidence="3">
        <location>
            <begin position="200"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="35"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL79163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="291" mass="31719" checksum="9CC6CD581B5133AD" modified="2016-01-20" version="1">MNRHQRPFAIITLIAALMLACSFSMQLTDPTATPQPPATLSPTSAPTDPPAPADTATAVFTPLPTIAPMPTQAEPPALQIVSQPIYIESASPYYVIEGSRPLMQNAGTAGDTFNTLVQQILDEQVNSFTTNLADIEEWRAENMPGMASTMHFDYSLLYNDNGIVSILINLDVYVAGAAHPSPFSITLNFDLTRGRDLALADLFTPGADYLGRIANLCKADLSTREYIDYLTGADPTLENYRSWNITPDGLLITFDAYQVAPYAAGPQTVLIEYSQLNDLIHQTSPLHNIPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XH02</accession>
    <name>A0A0P6XH02_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_04070</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061684.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79065">
        <property type="protein sequence ID" value="KPL79065"/>
        <property type="gene ID" value="ADN00_04070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="426" mass="47522" checksum="859EB8B2A3CC482D" modified="2016-01-20" version="1">MKKIIPFPRLLALLIIALTLLFTPGSLPRLPSTPYEQARVFTRSIEFDYVAWGARASLDKLRQIALGASHYLSEDQQKQVVMEYIDLVSQSVHLEAQIEQIYSEPSITDPQNFSIPWRDQLSQVQSRLKKTAPLAESILQQQISLTLRDLDLSALGQPIPPVLFQVTELPKALIISPRSVIRQDAFVSLEANLPLDQITGLEEQIARQMDVSALVEDVGGIGMYPTMIIRTTNLSFLIEVAAHEWIHNFLTLRPLGWNYDTSPELRSMNETTANLSGKEISQAVLRRFYPELLPKPQPAPSGTLSAAPIESPPSEPVFDFRAEMHTTRLKADELLAAGKIEEAEAYMEERRQLFLQNGYRIRKLNQAYFAFHGAYADVPGGAAGEDPVGPAVVALREKSPSLAAFLRRIAWITSLDDLQQAVSAPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XH08</accession>
    <name>A0A0P6XH08_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_02800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000013">
        <property type="protein sequence ID" value="KPL79382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061440.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000013.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02800"/>
    <dbReference type="EnsemblBacteria" id="KPL79382">
        <property type="protein sequence ID" value="KPL79382"/>
        <property type="gene ID" value="ADN00_02800"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007401">
        <property type="entry name" value="DUF454"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35813">
        <property type="entry name" value="PTHR35813"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04304">
        <property type="entry name" value="DUF454"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016789">
        <property type="entry name" value="DUF454"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="77"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="147" mass="16205" checksum="2E41E3EECE83E5F8" modified="2016-01-20" version="1">MKKRTPFQKFILSAAGILFVGLGILGMVLPLLPSTVFFLLAAAAFAHSSERLYTWLIEHKLFGSLIRDYRLYRAIPLRAKITSISLLWVTILYSAFGVIDSWPVRVLLLAIAAAVTIHILTIKTLKKEAPQPKAEAASGQSTLDQAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XIU6</accession>
    <name>A0A0P6XIU6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Glutamate--tRNA ligase</fullName>
            <ecNumber evidence="9">6.1.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Glutamyl-tRNA synthetase</fullName>
            <shortName evidence="9">GluRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">gltX</name>
        <name evidence="13" type="ORF">ADN00_02265</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the attachment of glutamate to tRNA(Glu) in a two-step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + L-glutamate + tRNA(Glu) = AMP + diphosphate + L-glutamyl-tRNA(Glu)</text>
            <dbReference type="Rhea" id="RHEA:23540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9663"/>
            <dbReference type="Rhea" id="RHEA-COMP:9680"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.17"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="9">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the class-I aminoacyl-tRNA synthetase family. Glutamate--tRNA ligase type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.17" evidence="9"/>
    <dbReference type="EMBL" id="LGCL01000009">
        <property type="protein sequence ID" value="KPL79806.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061339.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000009.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02265"/>
    <dbReference type="EnsemblBacteria" id="KPL79806">
        <property type="protein sequence ID" value="KPL79806"/>
        <property type="gene ID" value="ADN00_02265"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2775"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004818">
        <property type="term" value="F:glutamate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006424">
        <property type="term" value="P:glutamyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00808">
        <property type="entry name" value="GluRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00022">
        <property type="entry name" value="Glu_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045462">
        <property type="entry name" value="aa-tRNA-synth_I_cd-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020751">
        <property type="entry name" value="aa-tRNA-synth_I_codon-bd_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008925">
        <property type="entry name" value="aa_tRNA-synth_I_cd-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004527">
        <property type="entry name" value="Glu-tRNA-ligase_bac/mito"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020752">
        <property type="entry name" value="Glu-tRNA-synth_I_codon-bd_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000924">
        <property type="entry name" value="Glu/Gln-tRNA-synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020058">
        <property type="entry name" value="Glu/Gln-tRNA-synth_Ib_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033910">
        <property type="entry name" value="GluRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19269">
        <property type="entry name" value="Anticodon_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00749">
        <property type="entry name" value="tRNA-synt_1c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00987">
        <property type="entry name" value="TRNASYNTHGLU"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48163">
        <property type="entry name" value="SSF48163"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00464">
        <property type="entry name" value="gltX_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 10" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="6 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="5 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA-synt_1c" evidence="11">
        <location>
            <begin position="4"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="domain" description="Anticodon_2" evidence="12">
        <location>
            <begin position="343"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="9">
        <location>
            <begin position="10"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'KMSKS' region" evidence="9">
        <location>
            <begin position="252"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="255"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001818"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU363037"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF19269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KPL79806.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="493" mass="55886" checksum="7AD275D10CBC512A" modified="2016-01-20" version="1">MQPVRVRFAPSPTGRVHLGSGRTALYDYLIAKQTGGQFILRIEDTDQKRYVPGAEEELINGLRWLGIDWDEGPDVGGPYGPYRQSERKEIYQRYARELIDKGFAYPCFCTAERLQAVREQQLHNKEMPHYDGTCRNLRPEEASARIAAGEPYVVRFKTPKEGTTTVKDLLRGEINIENRQLDDYIIVKSDGLALYHLAAMVDDHLMKITHVIRGSEWLPTFPLHHLIYQAFGWDMPTFIHLSVFLKPSGKGKMSKRDAVDLDKEGYSIFLNDFKDLGYLPEGVVNWIALMGWSYDDHTEFFTMDDLIEKFSFEKLNPSPAAINFEKLDHFNGLHIRSLPVPVLAEQVKPFFEKGGYALTDDQLLQVAPIIQERLVTLDDAVEVAGFLFDEDIELVLEDLIPKKTTLEETLAIAKNCYEVLSGLPSLAPAVAEPPMRELVEKMGLKAGQVFGFLRQAATGRKVTPPLFESLEIIGKEKVLSRLKLAITLLESQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XJS2</accession>
    <name>A0A0P6XJS2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Corrinoid adenosyltransferase</fullName>
            <ecNumber evidence="4">2.5.1.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Cob(II)alamin adenosyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Cob(II)yrinic acid a,c-diamide adenosyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Cobinamide/cobalamin adenosyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_11875</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>2 ATP + 2 cob(II)alamin + reduced [electron-transfer flavoprotein] = 2 adenosylcob(III)alamin + 3 H(+) + oxidized [electron-transfer flavoprotein] + 2 triphosphate</text>
            <dbReference type="Rhea" id="RHEA:28671"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16304"/>
            <dbReference type="ChEBI" id="CHEBI:18036"/>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="EC" id="2.5.1.17"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>2 ATP + 2 cob(II)yrinate a,c diamide + reduced [electron-transfer flavoprotein] = 2 adenosylcob(III)yrinate a,c-diamide + 3 H(+) + oxidized [electron-transfer flavoprotein] + 2 triphosphate</text>
            <dbReference type="Rhea" id="RHEA:11528"/>
            <dbReference type="Rhea" id="RHEA-COMP:10685"/>
            <dbReference type="Rhea" id="RHEA-COMP:10686"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18036"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58307"/>
            <dbReference type="ChEBI" id="CHEBI:58503"/>
            <dbReference type="ChEBI" id="CHEBI:58537"/>
            <dbReference type="EC" id="2.5.1.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 2/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the Cob(I)alamin adenosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.17" evidence="4"/>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063232.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11875"/>
    <dbReference type="EnsemblBacteria" id="KPL76047">
        <property type="protein sequence ID" value="KPL76047"/>
        <property type="gene ID" value="ADN00_11875"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00148">
        <property type="reaction ID" value="UER00233"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008817">
        <property type="term" value="F:cob(I)yrinic acid a,c-diamide adenosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016030">
        <property type="entry name" value="CblAdoTrfase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036451">
        <property type="entry name" value="CblAdoTrfase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029499">
        <property type="entry name" value="PduO-typ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12213">
        <property type="entry name" value="PTHR12213"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01923">
        <property type="entry name" value="Cob_adeno_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89028">
        <property type="entry name" value="SSF89028"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00636">
        <property type="entry name" value="PduO_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Cob_adeno_trans" evidence="5">
        <location>
            <begin position="5"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU366026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL76047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="186" mass="20572" checksum="663E0CC151788521" modified="2016-01-20" version="1">MREFFTRRGDGGETGLLGDERIAKSDLRLEVLGSIDEANSALGMARSIAVREESRATLLKVQRDLYGLMSEIATTEKTANAFPKVAAEQVEWLEAMIAQLTNSTSIPREFIVPGDTPSGAALDVARTTVRRAERRCVALFQEDTQRNPEILKYLNRLSSLCFVMELSENQAASGKDSPTFAKQERS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XK52</accession>
    <name>A0A0P6XK52_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01505</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80547">
        <property type="protein sequence ID" value="KPL80547"/>
        <property type="gene ID" value="ADN00_01505"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="13"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="109" mass="11943" checksum="AE79BB208D518B43" modified="2016-01-20" version="1">MVFFLTRGADWLRQDADPTPSPSQHAGKGISGRGFGFMGRTAVRPHERSRASTPRHLPWLAGEGRDGVYVLPTLLINYGIVGFRAAIMPFTFTNPPAAQADLQVCFWVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKF7</accession>
    <name>A0A0P6XKF7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_11010</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Plastid</location>
            <location evidence="1">Chloroplast</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acyl-ACP thioesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063063.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11010"/>
    <dbReference type="EnsemblBacteria" id="KPL76495">
        <property type="protein sequence ID" value="KPL76495"/>
        <property type="gene ID" value="ADN00_11010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016297">
        <property type="term" value="F:acyl-[acyl-carrier-protein] hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002864">
        <property type="entry name" value="Acyl-ACP_thioesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045023">
        <property type="entry name" value="FATA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029069">
        <property type="entry name" value="HotDog_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31727">
        <property type="entry name" value="PTHR31727"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01643">
        <property type="entry name" value="Acyl-ACP_TE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54637">
        <property type="entry name" value="SSF54637"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0150">Chloroplast</keyword>
    <keyword evidence="4" id="KW-0934">Plastid</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0809">Transit peptide</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL76495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="245" mass="27702" checksum="D460D831C30BFBE7" modified="2016-01-20" version="1">MIQTVWTEVVEVQTHETDLLQRWRPSGLFRAIQTAGQHHASHLGYDYREMLLQNQSWVLARVRVEFERFPQAGEKITIQTWPKCIQQKLFFVRDFWITDASDQLVARASSAFVLIDTQARRILPPRALGGDLPSLPEKAAISSPLEKIVEVGQPSQALVRTAGYSVVDLMGHVNNAVYVDWVCDALPSSYFQERHLAAVQVNYNKEVRPAESVSIQVGQLDGQMSLKGVNQTTGEIAFEAQVEWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKG5</accession>
    <name>A0A0P6XKG5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">HTH dtxR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_15940</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the DtxR/MntR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL71992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064033.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL71992">
        <property type="protein sequence ID" value="KPL71992"/>
        <property type="gene ID" value="ADN00_15940"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007167">
        <property type="entry name" value="Fe-transptr_FeoA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001367">
        <property type="entry name" value="Fe_dep_repressor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036421">
        <property type="entry name" value="Fe_dep_repressor_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038157">
        <property type="entry name" value="FeoA_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022687">
        <property type="entry name" value="HTH_DTXR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022689">
        <property type="entry name" value="Iron_dep_repressor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008988">
        <property type="entry name" value="Transcriptional_repressor_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02742">
        <property type="entry name" value="Fe_dep_repr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01325">
        <property type="entry name" value="Fe_dep_repress"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04023">
        <property type="entry name" value="FeoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00899">
        <property type="entry name" value="FeoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00529">
        <property type="entry name" value="HTH_DTXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47979">
        <property type="entry name" value="SSF47979"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50037">
        <property type="entry name" value="SSF50037"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50944">
        <property type="entry name" value="HTH_DTXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH dtxR-type" evidence="8">
        <location>
            <begin position="8"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL71992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="226" mass="25137" checksum="5A6D8DE9A65B2C91" modified="2016-01-20" version="1">MDINSEVMSESEEMYLVTIARLIEDGTSSPIPLSTLAREMEILPVSANQMIRKMADEGLVEYIPYKGVELTHSGKTTVRRILRHRRLWEIFLVEKLGLPFSEAEALACRMEHITPDHISSQLSEFLGHPRFDSFGNPVPEVNEINLGENWVTLSAIDPGETISIIQIRTEPAMRSFLVSEGVGPGSKLQVAAVGPQNIVVKDTNEKVVKLERSIADSILVKVSETK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKV2</accession>
    <name>A0A0P6XKV2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CN hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01685</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061226.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01685"/>
    <dbReference type="EnsemblBacteria" id="KPL80580">
        <property type="protein sequence ID" value="KPL80580"/>
        <property type="gene ID" value="ADN00_01685"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1096"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="SSF56317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="1">
        <location>
            <begin position="3"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="289" mass="32621" checksum="15324B0EF71078D3" modified="2016-01-20" version="1">MKINLALAQINTRLGKVEDNLEKHLAYIQEATSNGADLVVFPELSLTGYVLQDLASAVAHKPVSTDPVFRPLLEASQKVDLMVGFVEEDARSRFYISAAYLSRGEVLHVHHKVYLPTYGLFDESRFFAWGDSLEAFDTPFGRLGMLICEDFWHASPPYLLWLDGADILLFQSASPGRGLTYESELNTAHWVDHINRAYASLFTSFVVHCNRVGFEDGLNFWGGASVYDPNGQVLLHASQFEETLAMCEIDLNELHRSRARLPLLRDERTALVQRELNRILTSRQSNCGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKV8</accession>
    <name>A0A0P6XKV8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">TMP_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_15685</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063974.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15685"/>
    <dbReference type="EnsemblBacteria" id="KPL72257">
        <property type="protein sequence ID" value="KPL72257"/>
        <property type="gene ID" value="ADN00_15685"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013491">
        <property type="entry name" value="Tape_meas_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20155">
        <property type="entry name" value="TMP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02675">
        <property type="entry name" value="tape_meas_nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TMP_3" evidence="1">
        <location>
            <begin position="85"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF20155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="671" mass="71186" checksum="036C3E19D5C0C1E0" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XL02</accession>
    <name>A0A0P6XL02_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09610</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062786.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09610"/>
    <dbReference type="EnsemblBacteria" id="KPL76852">
        <property type="protein sequence ID" value="KPL76852"/>
        <property type="gene ID" value="ADN00_09610"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2377"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041413">
        <property type="entry name" value="MLTR_LBD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17765">
        <property type="entry name" value="MLTR_LBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="32"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="280" mass="32204" checksum="F42E94C4D73610A1" modified="2016-01-20" version="1">MVANNEKLRHRELAGFLKTRRAKILPSQVGLAAAARRRTPGLRREEVAQLAGVSLTWYTWLEQGRPIQVSAQVVESLCRVLLLDRQERSHLYLLANQPLPADIPAYPSVVSPILQHVLDSFEICPAFIADQRWNVIAWNEAARFIFGDFTEMNARQRNIVWGMFTDPYYRQLYAHWDAHAKSLMGRFRSTCGKYIEDAWLNQFIEDLKAESPEFNLWWPLHEVHYDSSIFKQFNHPKAGALEFESSSFDVPDHSGLKLFVHVPVPASDTAAKMKRWLGEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XL59</accession>
    <name>A0A0P6XL59_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chemotaxis protein CheY</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_00180</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060937.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00180"/>
    <dbReference type="EnsemblBacteria" id="KPL81004">
        <property type="protein sequence ID" value="KPL81004"/>
        <property type="gene ID" value="ADN00_00180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="19"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL81004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="142" mass="16015" checksum="B0C4E2E1310D771C" modified="2016-01-20" version="1">MEQGWLYKENGVSADTHAKILYIEDDQEMIDLVSLILSRRGYEVKGAQGGRNGLEAIRNESFDLVLLDLMMPDLDGWDLYHILKSDEKTRDVPVIVITAKSQPIDKVLGLYIAKVEDYISKPFHPNELVASVEKVLSITPLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XL89</accession>
    <name>A0A0P6XL89_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Methylenetetrahydrofolate reductase</fullName>
            <ecNumber evidence="10">1.5.1.20</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">ADN00_10525</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2 10">
            <text>(6S)-5-methyl-5,6,7,8-tetrahydrofolate + NAD(+) = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H(+) + NADH</text>
            <dbReference type="Rhea" id="RHEA:19821"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:18608"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.5.1.20"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>(6S)-5-methyl-5,6,7,8-tetrahydrofolate + NADP(+) = (6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:19817"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:18608"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.5.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 10">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 10">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 10">Belongs to the methylenetetrahydrofolate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.1.20" evidence="10"/>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062957.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10525"/>
    <dbReference type="EnsemblBacteria" id="KPL76998">
        <property type="protein sequence ID" value="KPL76998"/>
        <property type="gene ID" value="ADN00_10525"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2576"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106312">
        <property type="term" value="F:methylenetetrahydrofolate reductase NADH activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106313">
        <property type="term" value="F:methylenetetrahydrofolate reductase NADPH activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00537">
        <property type="entry name" value="MTHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029041">
        <property type="entry name" value="FAD-linked_oxidoreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003171">
        <property type="entry name" value="Mehydrof_redctse-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004620">
        <property type="entry name" value="MTHF_reductase_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02219">
        <property type="entry name" value="MTHFR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51730">
        <property type="entry name" value="SSF51730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00676">
        <property type="entry name" value="fadh2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0274">FAD</keyword>
    <keyword evidence="6 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="9" id="KW-0520">NAD</keyword>
    <keyword evidence="8 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL76998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="300" mass="33819" checksum="2C8B933E4C6B7C7B" modified="2016-01-20" version="1">MKIADLLKTYKTIFSFEFFPARTPEASEELYQTMTELIPLQPSHVSVTYGAGGSTRELTHNLVLRLHNSAQLTVMPHLTCVGTTRDEVFEILTRYNDAGIENIMALRGDPPKGAEERAIPAGEGFPYAADLVAFIKQHFPQLSVGVAGFTEGHPATPNRLKEIEYLKAKVDAGADFIVTQLFFDNRDFYDYCERCQLAGIQVPVIAGIMPIISKRNMLRMAELAAGVRYPARLLRALARAEDDEDFAKIGRHWATEQVLDLLDHDVRGVHFYTLNKSRSTMQIYDALNLRKVMHSPENRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-08-12" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XL96</accession>
    <name>A0A0P6XL96_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10585</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062967.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77007">
        <property type="protein sequence ID" value="KPL77007"/>
        <property type="gene ID" value="ADN00_10585"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003718">
        <property type="entry name" value="OsmC/Ohr_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036102">
        <property type="entry name" value="OsmC/Ohrsf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02566">
        <property type="entry name" value="OsmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82784">
        <property type="entry name" value="SSF82784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="145" mass="15916" checksum="1FD4401300374F84" modified="2016-01-20" version="1">MPINKTVTISAKSVENFLIELNAGPHKQYIDQPETMGGKNAAPTPLDYFFFALGGCIITIAKIVAKQRQIEIRDMSVTVEGGCNTAVLMGKSKEDRAGFHHVVVKVNLDADMTDEEKIAFLEEVDSRCPISENIVNPTPVKIELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XLB6</accession>
    <name>A0A0P6XLB6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_10690</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77025">
        <property type="protein sequence ID" value="KPL77025"/>
        <property type="gene ID" value="ADN00_10690"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2612"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL77025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="512" mass="55518" checksum="E0B0B950F66ABD1B" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XLK6</accession>
    <name>A0A0P6XLK6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_11720</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063203.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76023">
        <property type="protein sequence ID" value="KPL76023"/>
        <property type="gene ID" value="ADN00_11720"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="5"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="170" mass="19384" checksum="760572D045FD8DDB" modified="2016-01-20" version="1">MRENVFLRRATPEDASAFLALKKALDVETAFLMLEPGERLTSEEEMRATLERIAAVERDYLAVMECDGELVGYLSAQSGSYRRNRHSAYITTGIRQAFCGQGWGKRLFADLIGWAKQSGITRLELTVMAHNQRAIGLYKRMGFLKEGVKRHSLRVDNQYIDEDYMALLLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XMH1</accession>
    <name>A0A0P6XMH1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_00475</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060990.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00475"/>
    <dbReference type="EnsemblBacteria" id="KPL81046">
        <property type="protein sequence ID" value="KPL81046"/>
        <property type="gene ID" value="ADN00_00475"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007016">
        <property type="entry name" value="O-antigen_ligase-related"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04932">
        <property type="entry name" value="Wzy_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="27"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="52"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="76"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="132"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="193"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="232"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="280"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="305"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="384"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="420"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="459"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL81046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="494" mass="55629" checksum="619E93A4DB2C3528" modified="2016-01-20" version="1">MTINQTEIQRNPKRLAQRIQEFYRTHMDFVVIFITIAIALILGLSASAIKPIVAVAISIIPALLIGFNFYTQNLQFSPIILLISGGVIPLYVSTGTASVVVDSLLLVVMISGLWILRSIVLEKRIQVEKKPYNIPLFAYMTIVAISLVWGTLFRDPTVITWSSFFKVQLAATTVMIMLPVTFLISSNLIRETWILKAMAIIMIIMGCYGYLYEIRFTHRLIWVFFNRTGLMVSNQGLFTMWVVVICVAWAFFDRGLKPYFKLGLLALAGVWIRYRFLINISWVTGWLPALTALGVLIWMRSKKLFLLLVLAILIVGLIKIDFIKEALAQEQTESGYTRLDAWAASLTLTKEHFLFGTGPGGYAAYYMTYFPDQAMATHNNYLDILAQTGIFGLISFVSFFAVVAFEGFKLCRRLKGKGDFLEALTNAVFAGTIGCIIAMGLGDWMVPFPYTQGIAAFDYIQYSWIFLGTIFAIKWIVDRDSSLSSNLKAGFRAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XMI5</accession>
    <name>A0A0P6XMI5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">3-isopropylmalate dehydratase large subunit</fullName>
            <ecNumber evidence="12">4.2.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Alpha-IPM isomerase</fullName>
            <shortName evidence="12">IPMI</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="12">Isopropylmalate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="primary">leuC</name>
        <name evidence="14" type="ORF">ADN00_19070</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 12">Catalyzes the isomerization between 2-isopropylmalate and 3-isopropylmalate, via the formation of 2-isopropylmaleate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>(2R,3S)-3-isopropylmalate = (2S)-2-isopropylmalate</text>
            <dbReference type="Rhea" id="RHEA:32287"/>
            <dbReference type="ChEBI" id="CHEBI:1178"/>
            <dbReference type="ChEBI" id="CHEBI:35121"/>
            <dbReference type="EC" id="4.2.1.33"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="12">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 12">Amino-acid biosynthesis; L-leucine biosynthesis; L-leucine from 3-methyl-2-oxobutanoate: step 2/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="12">Heterodimer of LeuC and LeuD.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the aconitase/IPM isomerase family. LeuC type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.33" evidence="12"/>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064630.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_19070"/>
    <dbReference type="EnsemblBacteria" id="KPL70137">
        <property type="protein sequence ID" value="KPL70137"/>
        <property type="gene ID" value="ADN00_19070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3127"/>
    <dbReference type="UniPathway" id="UPA00048">
        <property type="reaction ID" value="UER00071"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003861">
        <property type="term" value="F:3-isopropylmalate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01583">
        <property type="entry name" value="IPMI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01026">
        <property type="entry name" value="LeuC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004430">
        <property type="entry name" value="3-IsopropMal_deHydase_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018136">
        <property type="entry name" value="Aconitase_4Fe-4S_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033941">
        <property type="entry name" value="IPMI_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00415">
        <property type="entry name" value="ACONITASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="SSF53732"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00170">
        <property type="entry name" value="leuC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00450">
        <property type="entry name" value="ACONITASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01244">
        <property type="entry name" value="ACONITASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6 12" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="11 12" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="8 12" id="KW-0408">Iron</keyword>
    <keyword evidence="9 12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="14" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 12" id="KW-0432">Leucine biosynthesis</keyword>
    <keyword evidence="10 12 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="7 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aconitase" evidence="13">
        <location>
            <begin position="8"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="352"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="412"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="415"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KPL70137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="471" mass="50386" checksum="3DD458269C54FDD5" modified="2016-01-20" version="1">MKPRTLFEKIWEAHVVSQQPDAPAILYIDRQYLHEVTSPQAFAGLRERGLPARRPDRAFATVDHSIPTLFVPSGDRLSVADDASKTQIRQLEKNCADFGIPCYDHNSPDQGIVHVIGPEKGLTQPGMTIVCGDSHTSTHGAFGSLAFGIGTSEILQVLATQCLLQRKPKTMLVKIEGKLPAGISAKDIILALIAQIGIGGATGHVIEYGGEAIQMLNMDERMTICNMSIECGARAGMIAPDEVTFDYLKGREYAPSGSAWDAALAAWRQLPSDPGAQYDREVVLNATSLQPMVTFGTNPGMGIPVTASVPHPDKLENESQRAALQKALAYMGLQPGQPIAGQKVDVVFIGSCTNGRITDLRAAAEVLRGRKVADGLTVLVVPGSRAVLRQAEQEGLDRVFIEAGAQWRDAGCSMCIAMNGDMIQPGQYAISTSNRNFEGRQGKGGRTLLASPATAAASAVNGYVTDPREIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XNV6</accession>
    <name>A0A0P6XNV6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cadherin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_07320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062327.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07320"/>
    <dbReference type="EnsemblBacteria" id="KPL78269">
        <property type="protein sequence ID" value="KPL78269"/>
        <property type="gene ID" value="ADN00_07320"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3285"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002126">
        <property type="entry name" value="Cadherin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010221">
        <property type="entry name" value="VCBS_rpt"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01965">
        <property type="entry name" value="VCBS_repeat"/>
        <property type="match status" value="21"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50268">
        <property type="entry name" value="CADHERIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cadherin" evidence="1">
        <location>
            <begin position="1936"/>
            <end position="2072"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="2465" mass="255269" checksum="1270C7F3B8453E33" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XPA0</accession>
    <name>A0A0P6XPA0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_17890</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000043">
        <property type="protein sequence ID" value="KPL70905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70905">
        <property type="protein sequence ID" value="KPL70905"/>
        <property type="gene ID" value="ADN00_17890"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="75" mass="8619" checksum="92F408EAD84E7E71" modified="2016-01-20" version="1">MRTPNNNIFAFQDWKNARFLFKDESFARINRPHGSSFVNVIGAKGGVTHKERIKNSIKGAIWRITAARRPFMEIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XPJ6</accession>
    <name>A0A0P6XPJ6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_06570</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000017">
        <property type="protein sequence ID" value="KPL78580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78580">
        <property type="protein sequence ID" value="KPL78580"/>
        <property type="gene ID" value="ADN00_06570"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="150" mass="15718" checksum="9756F0EE75E724F6" modified="2016-01-20" version="1" fragment="single">SSSRTTFALNSAVNFLRSPILDLFLESYSTPLGGVQFLGSITGVSQPQISVGLHTMQLSLLHPFPGLPAGEEVDAAGGWGLTTADFDPFPGLPAGEGVGAAGGWGLTTADFDRAAWYAALFASPLPWLSCRGRGRRSRGMGSQTTGFRQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XPW0</accession>
    <name>A0A0P6XPW0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05705</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062006.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05705"/>
    <dbReference type="EnsemblBacteria" id="KPL78735">
        <property type="protein sequence ID" value="KPL78735"/>
        <property type="gene ID" value="ADN00_05705"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002822">
        <property type="entry name" value="Ni_insertion"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36566">
        <property type="entry name" value="PTHR36566"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01969">
        <property type="entry name" value="DUF111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0533">Nickel</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="395" mass="43363" checksum="2BBF2F640CCB94E1" modified="2016-01-20" version="1">MEKIAYITSGTPVNSTLLLAALLDLELQQAEIQTAIDQYHFSIPLQVQKKPGHDGNLRGKILQFRFPRHAEPPQIPLAAVIEKVSQQADQSSVLEILTTLVETGAQVHHTPTAQFIQQNSLPFQTLAEVIGFTHGLRSLGIEKLFCGALPLPVSASANPAAAWYESAALSQEILRQNQCLVTPVDQDTGWVTPSAAALLVHLAVFERPAFRLQSIGTGMEDQAAKGALQILVGERQAPAKPGNILIETNIDDMSPQILADVTVRLMEAGALDVYRIPIQMKKNRAGTRLAVVARPQDEERLAEMILRETSTIGLQTRPIEHKYRAKIEVKEFKTPYGIVPVKLKYSQGKVIQASPEYETCSALARQHQIPTLQVYQAALAACNPWAEETETSHQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQW5</accession>
    <name>A0A0P6XQW5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3 4">Single-stranded DNA-binding protein</fullName>
            <shortName evidence="2">SSB</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_08620</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homotetramer.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000022">
        <property type="protein sequence ID" value="KPL77651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062590.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000022.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08620"/>
    <dbReference type="EnsemblBacteria" id="KPL77651">
        <property type="protein sequence ID" value="KPL77651"/>
        <property type="gene ID" value="ADN00_08620"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1437"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04496">
        <property type="entry name" value="SSB_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00984">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000424">
        <property type="entry name" value="Primosome_PriB/ssb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011344">
        <property type="entry name" value="ssDNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10302">
        <property type="entry name" value="PTHR10302"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00436">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002070">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00621">
        <property type="entry name" value="ssb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50935">
        <property type="entry name" value="SSB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="108"/>
            <end position="135"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR002070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL77651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="135" mass="14635" checksum="F29AD6A5ED4E7A66" modified="2016-01-20" version="1">MYHKIILVGNLGRDPEMRYTPSGQAVTSFSVAVNDDFGENKRTIWVRVSAWGKTAENCNNFLKKGSKVLVEGRLTCDASTGGPRVYTRQDGSSGAAFEVSAQTVRFLSTRGEGGGGEDEYSMDSHEMSDAGDLPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQX6</accession>
    <name>A0A0P6XQX6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_08685</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000022">
        <property type="protein sequence ID" value="KPL77660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062602.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000022.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77660">
        <property type="protein sequence ID" value="KPL77660"/>
        <property type="gene ID" value="ADN00_08685"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="165"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="217"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="260"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="295"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="328"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="362"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="388"/>
            <end position="405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="665" mass="74370" checksum="EF11CC384362F399" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQZ1</accession>
    <name>A0A0P6XQZ1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_08825</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000022">
        <property type="protein sequence ID" value="KPL77678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062625.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000022.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77678">
        <property type="protein sequence ID" value="KPL77678"/>
        <property type="gene ID" value="ADN00_08825"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133181" evidence="1">
        <location>
            <begin position="28"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="249" mass="27444" checksum="A0D9582F7497F78B" modified="2016-01-20" version="1">MNPLRARRWWLAAAAGLMLACQLPLLGASLPEVIEHPAPDLRVDFSPFEAAGCQKDDSGWIRCPQGSPLDKLGCATLQPASDLLGGLQPADPIAVCVVRQPDEMDDETFEQQESVYRVGGLFPVLYRYVIWRDGGFILLANQQAVQQAFAPIESPQEALSYALALTNLDADYDLQASRGMRYFTDTLEETHVQETSGGYAMNLFRYQFLGCGPHPTYQVIVTVGRDGSISQGEPVKWFENPEEDGLCAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XRB2</accession>
    <name>A0A0P6XRB2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RNA polymerase sigma factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_03160</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the sigma-70 factor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000014">
        <property type="protein sequence ID" value="KPL79339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03160"/>
    <dbReference type="EnsemblBacteria" id="KPL79339">
        <property type="protein sequence ID" value="KPL79339"/>
        <property type="gene ID" value="ADN00_03160"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2044"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000943">
        <property type="entry name" value="RNA_pol_sigma70"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009042">
        <property type="entry name" value="RNA_pol_sigma70_r1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007624">
        <property type="entry name" value="RNA_pol_sigma70_r3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007127">
        <property type="entry name" value="RNA_pol_sigma_70_r1_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042189">
        <property type="entry name" value="RNA_pol_sigma_70_r1_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03979">
        <property type="entry name" value="Sigma70_r1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00140">
        <property type="entry name" value="Sigma70_r1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04539">
        <property type="entry name" value="Sigma70_r3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00046">
        <property type="entry name" value="SIGMA70FCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00715">
        <property type="entry name" value="SIGMA70_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00716">
        <property type="entry name" value="SIGMA70_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="RNA_pol_sigma70" evidence="7">
        <location>
            <begin position="188"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_sigma70" evidence="8">
        <location>
            <begin position="358"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU362124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS00715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL79339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="397" mass="45721" checksum="C17007C5B243DB92" modified="2016-01-20" version="1">MSDRRGRLATASKRTRMGDIIHILLEKADVVGYLTMDDLMQIYPEGGEDSERLNTVINALRRRGVELVDDDLADDEGDLFNGADYDPYVDMTAISTSDTVGLYMKEMARVPLLSVDEEIFLAKRIEGGEEAQQQLKGLNGNCTPEMRVELEQVVLDGQEAREHLIKANTRLVVSIAKRYIGRGVPFLDLIQEGNLGLMKAVKKYEYRRGFRFSTYATWWIRQTITRAIADQSRTIRVPVHMTDRIRQLYRKSHEMEQELGRAPNTDELARALKLPIKKVDWMLRVSWVPLSLESPINDDGEEAELGMFVEDTVTPTPMQSAYSKLLGEKIEQVLDTLPPREARILRLRFGLENGRTYTLEEVGQKFGLTRERIRQIESKALRRLRHPRRARQLREYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XSB5</accession>
    <name>A0A0P6XSB5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">DNA repair protein RadA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">radA</name>
        <name evidence="9" type="ORF">ADN00_12705</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">DNA-dependent ATPase involved in processing of recombination intermediates, plays a role in repairing DNA breaks. Stimulates the branch migration of RecA-mediated strand transfer reactions, allowing the 3' invading strand to extend heteroduplex DNA faster. Binds ssDNA in the presence of ADP but not other nucleotides, has ATPase activity that is stimulated by ssDNA and various branched DNA structures, but inhibited by SSB. Does not have RecA's homology-searching function.</text>
    </comment>
    <comment type="function">
        <text evidence="5">Plays a role in repairing double-strand DNA breaks, probably involving stabilizing or processing branched DNA or blocked replication forks.</text>
    </comment>
    <comment type="domain">
        <text evidence="5">The middle region has homology to RecA with ATPase motifs including the RadA KNRFG motif, while the C-terminus is homologous to Lon protease.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the RecA family. RadA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75503.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063393.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000027.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12705"/>
    <dbReference type="EnsemblBacteria" id="KPL75503">
        <property type="protein sequence ID" value="KPL75503"/>
        <property type="gene ID" value="ADN00_12705"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1234"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000725">
        <property type="term" value="P:recombinational repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01121">
        <property type="entry name" value="Sms"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01498">
        <property type="entry name" value="RadA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004504">
        <property type="entry name" value="DNA_repair_RadA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041166">
        <property type="entry name" value="Rubredoxin_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18073">
        <property type="entry name" value="Rubredoxin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00416">
        <property type="entry name" value="sms"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="5 6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0346">Stress response</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RECA_2" evidence="8">
        <location>
            <begin position="68"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="42"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Lon-protease-like" evidence="5">
        <location>
            <begin position="360"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="RadA KNRFG motif" evidence="5">
        <location>
            <begin position="261"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="97"/>
            <end position="104"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01498"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL75503.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="467" mass="50361" checksum="18184C2BC50A072D" modified="2016-01-20" version="1">MAKTQTRYVCQECGRVSARAMGRCPGCGAWDSLVEEIITAPSAKKDHPGGSSLLRSTPRPIGEIEGDSEDRLPLPMGEFSRVLGGGIVPGSIVLVGGDPGIGKSTLTLQMALLMAGQGKVLYVSGEESEKQIKMRALRLERDEEGNLRPLPETQLLVTETNLNTILEHIAAVNPGLVIIDSIQTVYLPEMDSTAGSVSQVRECASRLRELAKSSGIAMFLIGHVTKEGVIAGPRVLEHIVDTVLYLEGERFQFFRLLRSVKNRFGATSEVGVFEMRERGMVEVPNPSEAFLAERLVNAPGSAIAVTMEGTRPLLVEVQGLTSATSYGNPRRTPNGVDFNRLLLTTAVLTRRVGLKLGEQDVFVNVVGGLKVSEPAADLAVAAAIASSMRDVPVRADTVLIGEVGLSGELRWVSQMSARLNEAAKLGFKAAVVPRRVRRSEPWPPGIEILEARSIREAIKLALVSEER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XTA6</accession>
    <name>A0A0P6XTA6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_07650</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062388.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78318">
        <property type="protein sequence ID" value="KPL78318"/>
        <property type="gene ID" value="ADN00_07650"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="69" mass="7578" checksum="EEFDBB41611BDB8B" modified="2016-01-20" version="1">MPMLTFYSSSAAKGLRMALKIIVYQEALKNKSEMGLSMQMSRSFSPESMAVGAVRVWQAAGWAEGENLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUK2</accession>
    <name>A0A0P6XUK2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ABC transmembrane type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_15050</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000036">
        <property type="protein sequence ID" value="KPL73109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15050"/>
    <dbReference type="EnsemblBacteria" id="KPL73109">
        <property type="protein sequence ID" value="KPL73109"/>
        <property type="gene ID" value="ADN00_15050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1875"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015416">
        <property type="term" value="F:ABC-type phosphonate transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005769">
        <property type="entry name" value="PhnE/PtxC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01097">
        <property type="entry name" value="PhnE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="16"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="214"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="266"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="325"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="352"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="377"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="210"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL73109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="405" mass="44785" checksum="60F16A286B08DB92" modified="2016-01-20" version="1">MVDAFQMAQRPAKQRTGLFFFLIVVFFAFGWQIGQIDLVSFFTKAGDAGPALMRVLWPWQRAISYPEELSVSSAKILSPCGETPYPENVWEDKDRPFLKVNPTCGVPSEQDGEPGTTLTLTGEGFAPGEEGEVWWRDPIGNEFRQRQAGDYVKVMPDADGKFSVEIIFPYRLLPRGAGEKAQEWTIEVRQLAAVGDPEPSVELKLAIEKIIETIFIGMMATLFGIVLALPISFLAARNLMSGSRFSLAVYYITRTILNIIRSIEPLIWAIIAVIVVGLGPFAGILALTLHSLASLAKLYSEAIESIDHGPIEAIQATGANWLQTIMYAVVPQVIPPFVSFTIYRWDINIRMSTIIGFVGGGGIGFLLAQWIRLLDYSAAGIAVWFIAITVAILDYVSAEIRNRFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XV76</accession>
    <name>A0A0P6XV76_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_09430</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09430"/>
    <dbReference type="EnsemblBacteria" id="KPL77368">
        <property type="protein sequence ID" value="KPL77368"/>
        <property type="gene ID" value="ADN00_09430"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015276">
        <property type="term" value="F:ligand-gated ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001320">
        <property type="entry name" value="Iontro_rcpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00079">
        <property type="entry name" value="PBPe"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133235" evidence="2">
        <location>
            <begin position="20"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="domain" description="PBPb" evidence="3">
        <location>
            <begin position="43"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="PBPe" evidence="4">
        <location>
            <begin position="43"/>
            <end position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL77368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="277" mass="29992" checksum="F9626E55B6421B14" modified="2016-01-20" version="1">MVVFALVLAGCASAPSADAAGAADPEGCLGSAEEALVDLECREITIAVENAYLPFNYISSETGEPGGWDYDTWNEICTRLHCTPVFTEVAWDAMIQSVADGQYDVAADGITITDERAEIVDFSEGYINIVQRLLVRQGETRFASIEDFVANPELVLGTQASTTNYETALTYMSADRIQAFEQFPFAVQALIAGDVDAVIIDEVVGMGYLGENKEALELIGPNISSDQLGFVFPKGSDLVDPVNQAIQSMKDDGFLNEVNVKFFGPDFTITYDDIVTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XVA1</accession>
    <name>A0A0P6XVA1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SpoU_methylase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061180.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80536">
        <property type="protein sequence ID" value="KPL80536"/>
        <property type="gene ID" value="ADN00_01430"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029064">
        <property type="entry name" value="L30e-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55315">
        <property type="entry name" value="SSF55315"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SpoU_methylase" evidence="1">
        <location>
            <begin position="115"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="414" mass="45381" checksum="719E01DEE95A0B0E" modified="2016-01-20" version="1">MNKLEEIHTIKDPRVIEARELASAAGRRAAGKCLLEGEQALAWALHSGWMVERVFCAASQADLPLLSDLQQKGCQVCHASEGILKKISDTNYLIPLIGVARIPAENLRHRPRGDFVLVLDDVRDHGNIGTILRTAQAFGVREVVSTTGELDLFYRKMVDASRGTVFRTLLTPYASVSESIAALKAAGYQIVATSPYAPSLQSAARLQPRPVALVVGNETRGIDPLWVENADMVVQIPMSRQVESLNVGVAAGISIYELKWKLVMAMLINLIRSTLGRELNVTGKHVQLALDARLREVTPLNSTQVILLMVMKCDGSMTSDQVARDTAHFGEELQALIAPLQTEGLVAQSEEGLRLTEKGETTLAQLWGVVERSQEEILEGFSEAERGALMEYLRRIQTNCTHILAEASDSLPKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XW61</accession>
    <name>A0A0P6XW61_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_08760</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000022">
        <property type="protein sequence ID" value="KPL77670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062615.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000022.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77670">
        <property type="protein sequence ID" value="KPL77670"/>
        <property type="gene ID" value="ADN00_08760"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="17"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="226"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="420" mass="46983" checksum="31A24546FD9A2FA6" modified="2016-01-20" version="1">MKQLKIALIHYAAPPIIGGVESVMGQHARLMAADGHQVTIFAGRGAPFDERVAWQEIPLLDSAHPRVLRAKKSLNKGKLPADFNGLQAEILQDLRQHLAPFDVIIAHNLCSLHKNLAATAALRQYAAENPAQRLVLWHHDLAWCAPRYRAELHPGWPWNLIAEDWPETNRRHVVVSQFRREELSGLMGLPPEQIAVVPSGLEAAQFYKLHPFTAGFIQKSRLLEAWPILLLPVRITRRKNIELAIESLAALKEQFPQAALVITGPPGAHNPANQQYFEELVRLRDGLGLRPQPGAGGGAYLMAEIENDFLPNEVIYDFYRVADALFMPSHEEGFGIPILEAGLEGMPIFCSDILPFREIAAENATYFQLNQPPAEVAALMAGQLARVPALRHRARVRQTYTWEGIYRARILPLLSEVPHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XWR0</accession>
    <name>A0A0P6XWR0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_00230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060946.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00230"/>
    <dbReference type="EnsemblBacteria" id="KPL81012">
        <property type="protein sequence ID" value="KPL81012"/>
        <property type="gene ID" value="ADN00_00230"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3440"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010787">
        <property type="entry name" value="DUF1385"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07136">
        <property type="entry name" value="DUF1385"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL81012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="297" mass="32508" checksum="B3C2A5AC0E64064F" modified="2016-01-20" version="1">MDSPEKLPSYGGQAIIEGVMMRGQNSVAAAMRAPDGSIIIQDENLSGIYKSEIRKIPLLRGLIILWDALGLGTRFLTVSANVQTGEDEKIEGASLILTLVGSFAVAIALFFLLPAAAAEGLQRWLGWSAWVSNLVEGLVRLVILVAYIWGIGKMEDIQRVFAYHGAEHKTINAFEAGEDLTPENVKKYSVEHARCGTAFLLTVVLFSIIIFSALGPLSLAWRLASRVLLIPVVAGLAYEYIRWSGKHLDSPVVQWLIKPNLALQHLTTREPSLDMIEVAIAAFKAMVARENDQKVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XX07</accession>
    <name>A0A0P6XX07_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_00605</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061013.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00605"/>
    <dbReference type="EnsemblBacteria" id="KPL81067">
        <property type="protein sequence ID" value="KPL81067"/>
        <property type="gene ID" value="ADN00_00605"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="40"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="510"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="631"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="805"/>
            <end position="840"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL81067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="1071" mass="117909" checksum="48790F0F10D107C3" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XX90</accession>
    <name>A0A0P6XX90_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aldehyde-alcohol dehydrogenase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_00380</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">In the C-terminal section; belongs to the iron-containing alcohol dehydrogenase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">In the N-terminal section; belongs to the aldehyde dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00380"/>
    <dbReference type="EnsemblBacteria" id="KPL81140">
        <property type="protein sequence ID" value="KPL81140"/>
        <property type="gene ID" value="ADN00_00380"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3469"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008774">
        <property type="term" value="F:acetaldehyde dehydrogenase (acetylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004022">
        <property type="term" value="F:alcohol dehydrogenase (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006066">
        <property type="term" value="P:alcohol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015976">
        <property type="term" value="P:carbon utilization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08178">
        <property type="entry name" value="AAD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034789">
        <property type="entry name" value="AAD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001670">
        <property type="entry name" value="ADH_Fe/GldA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018211">
        <property type="entry name" value="ADH_Fe_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039697">
        <property type="entry name" value="Alcohol_dehydrogenase_Fe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012079">
        <property type="entry name" value="Bifunc_Ald-ADH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11496">
        <property type="entry name" value="PTHR11496"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00465">
        <property type="entry name" value="Fe-ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000111">
        <property type="entry name" value="ALDH_ADH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00913">
        <property type="entry name" value="ADH_IRON_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00060">
        <property type="entry name" value="ADH_IRON_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="4">
        <location>
            <begin position="2"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="Fe-ADH" evidence="5">
        <location>
            <begin position="447"/>
            <end position="837"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL81140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="851" mass="92466" checksum="E8C09147DAFB0645" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XXW1</accession>
    <name>A0A0P6XXW1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_01290</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000003">
        <property type="protein sequence ID" value="KPL80851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061154.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000003.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80851">
        <property type="protein sequence ID" value="KPL80851"/>
        <property type="gene ID" value="ADN00_01290"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL80851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="283" mass="31957" checksum="88EDB6A35EC56C36" modified="2016-01-20" version="1">MGPPHLLREEVLGLRGRLADLLGQEDVFQAILSQALYEKRLQRQQEFKVWLSSRLQIFGYHDLPFGPVADGSKKIDERFDFPIKGTPAQFGVMLRQFALNLRAQSQYQQLASQILLPGSRKDAGSISADANPVEVKLMLARNLLTIHAHALPSDGTLLRVRLHGERTLWSLWDAIRDELEKLGWFSLPELPEIPAPVETKPESQPQAASTAAEIWLSIPDIGANREILRHWHKGLTCDQIAVRVSLSPKTVLNRVNQLRKEHGAEVVPYRKSGVFQNFRKKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y039</accession>
    <name>A0A0P6Y039_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glyco_trans_2-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13315</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063513.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000031.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13315"/>
    <dbReference type="EnsemblBacteria" id="KPL74819">
        <property type="protein sequence ID" value="KPL74819"/>
        <property type="gene ID" value="ADN00_13315"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="9"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74819.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="336" mass="38161" checksum="2366DFB670DA6C0B" modified="2016-01-20" version="1">MTIQPLSVCVIVPVYNGEKTIAACLESLLQQQFNAGPFEIIVVENGSTDRTQAIVQTYPVRVIQCERKGPAYARNVGARHTQADILAFTDADCVADPDWLEELIQPFSDEEIGGCGGRIEAALDANSTFAEFFCQKRNTLTNYISGVHEYLPHLYTANAAYRRDVFERVGGFNANLLTAEDVDLSWRVQIAGGVRIGYADRAVIYHHHRSTMKALTRQYRQYGFGEILVDTLYREAPGYPRTPGYQMRQIFRQVMALPRYLLSMGVRRVKRWMNRADAYAVAEPEINLQVEWSNIRGKISGLWATRGMRTVEHVFQLDPQQMIDQFYGKAVKRGIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y3H2</accession>
    <name>A0A0P6Y3H2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">30S ribosomal protein S19</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsS</name>
        <name evidence="7" type="ORF">ADN00_12580</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Protein S19 forms a complex with S13 that binds strongly to the 16S ribosomal RNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76163.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063366.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12580"/>
    <dbReference type="EnsemblBacteria" id="KPL76163">
        <property type="protein sequence ID" value="KPL76163"/>
        <property type="gene ID" value="ADN00_12580"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3997"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00531">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020934">
        <property type="entry name" value="Ribosomal_S15/S19_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002222">
        <property type="entry name" value="Ribosomal_S19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005732">
        <property type="entry name" value="Ribosomal_S19_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023575">
        <property type="entry name" value="Ribosomal_S19_S15_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11880">
        <property type="entry name" value="PTHR11880"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00203">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002144">
        <property type="entry name" value="Ribosomal_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00975">
        <property type="entry name" value="RIBOSOMALS19"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54570">
        <property type="entry name" value="SSF54570"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01050">
        <property type="entry name" value="rpsS_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00323">
        <property type="entry name" value="RIBOSOMAL_S19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL76163.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="92" mass="10643" checksum="A8F672D250FCF14D" modified="2016-01-20" version="1">MSRSLKKGPFIEPKLLKKIEDMNARNEKKVLRTWSRASVIFPQMVGHTIAVHDGRRHVPIYVTDNMVGHRLGEFAPTRHFRGHVAEKSSKKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y4M4</accession>
    <name>A0A0P6Y4M4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PTS EIIA type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_11330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063126.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11330"/>
    <dbReference type="EnsemblBacteria" id="KPL76547">
        <property type="protein sequence ID" value="KPL76547"/>
        <property type="gene ID" value="ADN00_11330"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.965"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00211">
        <property type="entry name" value="PTS_IIA_fru"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016152">
        <property type="entry name" value="PTrfase/Anion_transptr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002178">
        <property type="entry name" value="PTS_EIIA_type-2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00359">
        <property type="entry name" value="PTS_EIIA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55804">
        <property type="entry name" value="SSF55804"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51094">
        <property type="entry name" value="PTS_EIIA_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PTS EIIA type-2" evidence="1">
        <location>
            <begin position="7"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="154" mass="16532" checksum="587984E10CE0E3F7" modified="2016-01-20" version="1">MSETIVRFLEPEAVVLGLKATTAREVIDTLGGKLMQAGYVRESFVEAALTRENSLPTGLPLAGEVNAAIPHTDVEHVLKPGLALATLAAPVVFKNMINPEEDVPVSLVFVMALDQPKAQVEMLQEIAGLLQNDALVSLLMQAKTYEEVKQALLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y673</accession>
    <name>A0A0P6Y673_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10565</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10565"/>
    <dbReference type="EnsemblBacteria" id="KPL77077">
        <property type="protein sequence ID" value="KPL77077"/>
        <property type="gene ID" value="ADN00_10565"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133388" evidence="1">
        <location>
            <begin position="19"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="136" mass="14723" checksum="BBF2A412B51FEF83" modified="2016-01-20" version="1">MLMIIAAALALAACAPLAGSKSEQTEMEYGEGATVEKIDLLALESFPVQINAALSGYLSDGCTEIERVEQERRENVFELKVITRRPKDAICTMQLAPFEESVALEVNGLPAGEYVVRVGDVETAFTLNADNILKSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y6Y4</accession>
    <name>A0A0P6Y6Y4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Deoxyribose-phosphate aldolase</fullName>
            <shortName evidence="3">DERA</shortName>
            <ecNumber evidence="3">4.1.2.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">2-deoxy-D-ribose 5-phosphate aldolase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Phosphodeoxyriboaldolase</fullName>
            <shortName evidence="3">Deoxyriboaldolase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">deoC</name>
        <name evidence="4" type="ORF">ADN00_09495</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes a reversible aldol reaction between acetaldehyde and D-glyceraldehyde 3-phosphate to generate 2-deoxy-D-ribose 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>2-deoxy-D-ribose 5-phosphate = acetaldehyde + D-glyceraldehyde 3-phosphate</text>
            <dbReference type="Rhea" id="RHEA:12821"/>
            <dbReference type="ChEBI" id="CHEBI:15343"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="ChEBI" id="CHEBI:62877"/>
            <dbReference type="EC" id="4.1.2.4"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate degradation; 2-deoxy-D-ribose 1-phosphate degradation; D-glyceraldehyde 3-phosphate and acetaldehyde from 2-deoxy-alpha-D-ribose 1-phosphate: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the DeoC/FbaB aldolase family. DeoC type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.4" evidence="3"/>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062751.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09495"/>
    <dbReference type="EnsemblBacteria" id="KPL77342">
        <property type="protein sequence ID" value="KPL77342"/>
        <property type="gene ID" value="ADN00_09495"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4138"/>
    <dbReference type="UniPathway" id="UPA00002">
        <property type="reaction ID" value="UER00468"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004139">
        <property type="term" value="F:deoxyribose-phosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009264">
        <property type="term" value="P:deoxyribonucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046386">
        <property type="term" value="P:deoxyribose phosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00959">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00114">
        <property type="entry name" value="DeoC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011343">
        <property type="entry name" value="DeoC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002915">
        <property type="entry name" value="DeoC/FbaB/LacD_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028581">
        <property type="entry name" value="DeoC_typeI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10889">
        <property type="entry name" value="PTHR10889"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10889:SF1">
        <property type="entry name" value="PTHR10889:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01791">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001357">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01133">
        <property type="entry name" value="DeoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00126">
        <property type="entry name" value="deoC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0704">Schiff base</keyword>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="94"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with acetaldehyde" evidence="3">
        <location>
            <position position="156"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL77342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="239" mass="26116" checksum="F12C8AD13F2C3D2E" modified="2016-01-20" version="1">MKITYVQFAKMIDASALKLDTSYDDFHALVDACKKYQFGCAFIWPAYSAELRDALAGTGIEFGTSLSFPSGQEPLEIKVHQARYFTSLGADQVDMVLNIGFLKSGRYEKVREEIVAVRDATKYTSLKVIIEAMLLSDEEIVKACEIVADCGANYVKSGTGFSAAPTTLHHIAVMKKTVGDRCKIKAAGGVRSLDLLTKMYALGVTQFGIGLSSAISIAEEAIACKDEIEIPEIRIEDYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y703</accession>
    <name>A0A0P6Y703_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_09195</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062772.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09195"/>
    <dbReference type="EnsemblBacteria" id="KPL77360">
        <property type="protein sequence ID" value="KPL77360"/>
        <property type="gene ID" value="ADN00_09195"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4073"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030158">
        <property type="entry name" value="MglC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32196:SF18">
        <property type="entry name" value="PTHR32196:SF18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="106"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="135"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="185"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="285"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="313"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL77360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="337" mass="36021" checksum="5210F394C3208276" modified="2016-01-20" version="1">MALPKGKKFVDYIVDNAIIFVLLILLVVIIVVEPSFISIRNFRNILSQASTRLIFALGVGGIIIAKGTDLSLGRQVGLAAVISASLLQGVDYTYRMYPDLPELPIIVPIILVMLITTLFSAINGFVIAKLKVDPFVATLGMMIIVYGVTSIYFDRPPYGAQPIGGLSPKFANFAQGSVNIGTFSIPYLIIYAALVTTLIFVLWNKTKFGKNMYAIGGNIDAAIVSGVNVFRNLMFVYMLAGMLYGLGGALEAARIGSATNNTGNGYELDAISACIVGGLSFNGGIGTVGGIIFGTLIFQVIAYGLSFIGVNPYLQYIIKGLIIVIAVAIDSAKYRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YCP1</accession>
    <name>A0A0P6YCP1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Phosphomannomutase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">ADN00_02120</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the phosphohexose mutase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000009">
        <property type="protein sequence ID" value="KPL79783.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061312.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000009.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02120"/>
    <dbReference type="EnsemblBacteria" id="KPL79783">
        <property type="protein sequence ID" value="KPL79783"/>
        <property type="gene ID" value="ADN00_02120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016868">
        <property type="term" value="F:intramolecular transferase activity, phosphotransferases"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005844">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016055">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-I/II/III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005845">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005846">
        <property type="entry name" value="A-D-PHexomutase_a/b/a-III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005843">
        <property type="entry name" value="A-D-PHexomutase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036900">
        <property type="entry name" value="A-D-PHexomutase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016066">
        <property type="entry name" value="A-D-PHexomutase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005841">
        <property type="entry name" value="Alpha-D-phosphohexomutase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02878">
        <property type="entry name" value="PGM_PMM_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02879">
        <property type="entry name" value="PGM_PMM_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02880">
        <property type="entry name" value="PGM_PMM_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00408">
        <property type="entry name" value="PGM_PMM_IV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00509">
        <property type="entry name" value="PGMPMM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53738">
        <property type="entry name" value="SSF53738"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55957">
        <property type="entry name" value="SSF55957"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00710">
        <property type="entry name" value="PGM_PMM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PGM_PMM_I" evidence="8">
        <location>
            <begin position="5"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_II" evidence="9">
        <location>
            <begin position="164"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_III" evidence="10">
        <location>
            <begin position="272"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="PGM_PMM_IV" evidence="7">
        <location>
            <begin position="421"/>
            <end position="461"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02879"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL79783.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="473" mass="52020" checksum="3E6B4D8E70791A5C" modified="2016-01-20" version="1">MAFKIKFGTDGWRGKIAEDYTFDNVRRCAQGYANYFNQIGKSGKWIVVGHDMRFHSENFALATAEVLVANGFKVYLTDGPTPTPVIAYAIVNKKAAGGINITASHNPPTDNGFKVRDENGGAIDPEGLKKIESLIPDEMEAVKRVSAKEAEADGRIVRFDPAPAYIENIQKLVDLEPIRQAGFKILVDPMWGNGIGWFPRLLAGGKTEVIEIHNHRNPTFPEMSRPEPIPPNINVGLQTTVDQNADVLIILDGDADRVGIGDEKGNFINQLQVYALLALYLLEVKGQRGPIVKTLSTTSMLEKLGKLYNIPVHETGVGFKYVAPKMMETNAMIGGEESGGYAFANHVPERDGILAGLFMLDMMVKLKSKPSELLALLFSKIGAHYYDRIDREFSGNRSDREAKIVNANPPTIGGLKVTGLNTMDGFKFGLEDGGWLLIRFSGTEPIMRVYCETTHADRVQPILQDGLRIAGLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YFS6</accession>
    <name>A0A0P6YFS6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_00535</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061001.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL81054">
        <property type="protein sequence ID" value="KPL81054"/>
        <property type="gene ID" value="ADN00_00535"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL81054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="74" mass="8157" checksum="848A28C0A5199A0A" modified="2016-01-20" version="1">MPKDLNEYRKETDRRLIIGGLAILFIVGGGLIYVLYGSGAALSGLLCAAFGLFPILAIVLLFWLLDKFLKNNQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YFZ5</accession>
    <name>A0A0P6YFZ5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_00225</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00225"/>
    <dbReference type="EnsemblBacteria" id="KPL81136">
        <property type="protein sequence ID" value="KPL81136"/>
        <property type="gene ID" value="ADN00_00225"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004509">
        <property type="entry name" value="Competence_ComEA_HhH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003583">
        <property type="entry name" value="Hlx-hairpin-Hlx_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019554">
        <property type="entry name" value="Soluble_ligand-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10531">
        <property type="entry name" value="SLBB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00278">
        <property type="entry name" value="HhH1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00426">
        <property type="entry name" value="TIGR00426"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HhH1" evidence="1">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="HhH1" evidence="1">
        <location>
            <begin position="150"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL81136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="172" mass="18337" checksum="142CD4E792B536A7" modified="2016-01-20" version="1">MAIGVLIGLLSAGLILFVSSPPLNEPVIVLPTYTAEPVWIHISGAVANPGVYALASPSRLQDAIQAAGGLSPQADQTKINLASFISDGQKIIVPLQGEKIETYTEDSSSTQININTASYEEIEALPGIGPQKASDILKYRETHGPFQSIDDLLKVNGIGEKTLQQIRPYITL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GKL6</accession>
    <name>A0A0N8GKL6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Hydrolase_4 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_18455</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064521.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18455"/>
    <dbReference type="EnsemblBacteria" id="KPL70042">
        <property type="protein sequence ID" value="KPL70042"/>
        <property type="gene ID" value="ADN00_18455"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052689">
        <property type="term" value="F:carboxylic ester hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012354">
        <property type="entry name" value="Esterase_lipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022742">
        <property type="entry name" value="Hydrolase_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12146">
        <property type="entry name" value="Hydrolase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017388">
        <property type="entry name" value="Esterase_lipase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hydrolase_4" evidence="2">
        <location>
            <begin position="19"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="1">
        <location>
            <position position="202"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="1">
        <location>
            <position position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR017388-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL70042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="259" mass="28706" checksum="63C6AD8AAA088CA0" modified="2016-01-20" version="1">MALHPLIPGAEPFFYPGNRTGVLLVHGFTGTPFEMREMGQNLAARGLTVLGIRLAGHASTPADMRSVRWGDWLANVEDGLNYLKNASDEVFLAGLSLGAILSLVAAARWDGLYPIRGVISLSCVVNLPSDWRVSFIRPLSLLQPYQQQAPGDFRNADAAANHICYPRYPTRSLAELRDLMAVMRAELERVRVPVFLAQSRLDAIAGPRSLPYLAEHLKNAPQTHLWLERSGHVINREPEREQLFDAAYTFIRAHSALTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GLB8</accession>
    <name>A0A0N8GLB8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_16410</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064123.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16410"/>
    <dbReference type="EnsemblBacteria" id="KPL72058">
        <property type="protein sequence ID" value="KPL72058"/>
        <property type="gene ID" value="ADN00_16410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010038">
        <property type="entry name" value="MoaD_arc-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016155">
        <property type="entry name" value="Mopterin_synth/thiamin_S_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003749">
        <property type="entry name" value="ThiS/MoaD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02597">
        <property type="entry name" value="ThiS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54285">
        <property type="entry name" value="SSF54285"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01687">
        <property type="entry name" value="moaD_arch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="91" mass="10190" checksum="6DE9537DF5D1FC44" modified="2016-01-20" version="1">MEIRYFATLREVTSVREETWPATACTLEELIRGLCAKYGHEFQKWVSCEDGGYGSLSIFLVNGQDYRSLNGLKTVLQQNDVISLFPPLAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GLW1</accession>
    <name>A0A0N8GLW1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_14550</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000035">
        <property type="protein sequence ID" value="KPL73602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14550"/>
    <dbReference type="EnsemblBacteria" id="KPL73602">
        <property type="protein sequence ID" value="KPL73602"/>
        <property type="gene ID" value="ADN00_14550"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2076"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022292">
        <property type="entry name" value="CHP03843"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03843">
        <property type="entry name" value="TIGR03843"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL73602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="245" mass="28064" checksum="EB8EB3D708740250" modified="2016-01-20" version="1">MERNFCVNKTFLLEALQKGVMNLQGQFLNSSNYTFLTQLAYQGFECNVVYKPVKGEMPLWDFPNGTLAQRETAAFVLSEALGWDLVPPTVFRKKAALGPGSVQYFVEHDPQYHFFEFSVEDRQRLRPAALFDLLANNADRKGGHILIGAERHIYLIDHGICFNREPKLRTVIWDFAGEALPPDLLEDVRRLSAELEQKTGAYTELRRYLSAKELDALRERALALLEAGVFPHPDPQRRPYPWPPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GM53</accession>
    <name>A0A0N8GM53_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Fructose-bisphosphate aldolase</fullName>
            <ecNumber evidence="4">4.1.2.13</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_13630</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="3">Binds 2 Zn(2+) ions per subunit. One is catalytic and the other provides a structural contribution.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.13" evidence="4"/>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063576.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000032.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13630"/>
    <dbReference type="EnsemblBacteria" id="KPL74338">
        <property type="protein sequence ID" value="KPL74338"/>
        <property type="gene ID" value="ADN00_13630"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1302"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004332">
        <property type="term" value="F:fructose-bisphosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00947">
        <property type="entry name" value="TBP_aldolase_IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000771">
        <property type="entry name" value="FBA_II"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01116">
        <property type="entry name" value="F_bP_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001359">
        <property type="entry name" value="F_bP_aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00167">
        <property type="entry name" value="cbbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00806">
        <property type="entry name" value="ALDOLASE_CLASS_II_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <feature type="region of interest" description="Dihydroxyacetone phosphate binding" evidence="2">
        <location>
            <begin position="211"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Dihydroxyacetone phosphate binding" evidence="2">
        <location>
            <begin position="253"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="1">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>dihydroxyacetone phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="210"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR001359-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL74338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="316" mass="34742" checksum="6772C6D1D063F3AB" modified="2016-01-20" version="1">MIVTTEKLFEAAYGKYAIGAYNINNLEQTMGLFRGCIDSKAPFIIQISKGARSYTHKNMLEALIRAADEIFPEAVFAVHLDHGDEATCMDCIQSGFYSSVMIDASHEDFDKNIEITRRVVEAAHARGIVVEAELGQLGGVEEHVQVSEADAHLTDPETAKEFVERSGCDSLAVAIGTSHGAYKFSGSQALRFDILSEIQKKLPGFPLVMHGSSSVPQEEVERINAAGGQLKGAKGVDATQFRRAAELGVTKINIDTDGRLVWTRVHREFFKEHPENFDLRPPGKEFMAAYAKFIAEKNDYLGSAGELDAVWKLIKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GM55</accession>
    <name>A0A0N8GM55_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_13725</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13725"/>
    <dbReference type="EnsemblBacteria" id="KPL74354">
        <property type="protein sequence ID" value="KPL74354"/>
        <property type="gene ID" value="ADN00_13725"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00092">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="SSF46565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="1">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="88"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL74354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="456" mass="51585" checksum="265DA91128248D39" modified="2016-01-20" version="1">MHPDVNPDPSIREEFLKIQDAFEVLSNISRRERYDLTLSEADLNPLFSVEFLVSRDQIAWKKEAQLVYGLLKFTATGEMDVSRQVPRCISLVIDRSTSMKGERMEVVKANVLQLFKRLNPQDIISIVTFSDRAELVLPPTPADELQRHEYPVMSIQTSGGTEIFHGLELGYKKLLEVVNGNQDAHLILLTDGHTYGDEEKCFALARDAALHGIVISGLGIGAEWNDEFLDQLASITGGNTSFVRSSKELARYLDEKIGVRSTVFAKNIHLDCVQDPLISMNYAYRISPNTSEIGIEDVLPLGMLRYKENLSILCEFAVNDLPDDKDEIRIIDGWLLFNLPGEAQPRRIYLHQTLKITDSSDDWQPPAEILKALSKINLYRMHEKVRAHIKTGNIEGATQYLKNLATNLLSMGDLDLAKVVIRESENIEQHHRMSQEGDKRIKYGTRALLLPSGQER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GM58</accession>
    <name>A0A0N8GM58_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">50S ribosomal protein L9</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rplI</name>
        <name evidence="10" type="ORF">ADN00_13890</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Binds to the 23S rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the bacterial ribosomal protein bL9 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063623.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000032.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13890"/>
    <dbReference type="EnsemblBacteria" id="KPL74378">
        <property type="protein sequence ID" value="KPL74378"/>
        <property type="gene ID" value="ADN00_13890"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1356"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.430.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.5.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00503">
        <property type="entry name" value="Ribosomal_L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000244">
        <property type="entry name" value="Ribosomal_L9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009027">
        <property type="entry name" value="Ribosomal_L9/RNase_H1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020594">
        <property type="entry name" value="Ribosomal_L9_bac/chp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020069">
        <property type="entry name" value="Ribosomal_L9_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036791">
        <property type="entry name" value="Ribosomal_L9_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020070">
        <property type="entry name" value="Ribosomal_L9_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036935">
        <property type="entry name" value="Ribosomal_L9_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21368">
        <property type="entry name" value="PTHR21368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03948">
        <property type="entry name" value="Ribosomal_L9_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01281">
        <property type="entry name" value="Ribosomal_L9_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55653">
        <property type="entry name" value="SSF55653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55658">
        <property type="entry name" value="SSF55658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00158">
        <property type="entry name" value="L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00651">
        <property type="entry name" value="RIBOSOMAL_L9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 7" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="RIBOSOMAL_L9" evidence="9">
        <location>
            <begin position="13"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="151"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS00651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL74378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="173" mass="18751" checksum="1A979032B45E7F40" modified="2016-01-20" version="1">MKVMLLKDVYKLGRAGDVKKVADGYGRNFLIPQGLAVLATVGALKQVDRLRTRAAAQRAALNTEMQSVAAKLADLVLVFSSKAGETGKLYGSVTTQEIAEAINAKTGLEIDKRQIECEPIRTLGEHSARVRLTIDLVPHIKVMVYREGEAPVAEQPAQAEPVVEEQAEEQAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMB7</accession>
    <name>A0A0N8GMB7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Beta-glucosidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_13520</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74850.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063551.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000031.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13520"/>
    <dbReference type="EnsemblBacteria" id="KPL74850">
        <property type="protein sequence ID" value="KPL74850"/>
        <property type="gene ID" value="ADN00_13520"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1197"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009044">
        <property type="term" value="F:xylan 1,4-beta-xylosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045493">
        <property type="term" value="P:xylan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044993">
        <property type="entry name" value="BXL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026891">
        <property type="entry name" value="Fn3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002772">
        <property type="entry name" value="Glyco_hydro_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42721">
        <property type="entry name" value="PTHR42721"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14310">
        <property type="entry name" value="Fn3-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01915">
        <property type="entry name" value="Glyco_hydro_3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SMART" id="SM01217">
        <property type="entry name" value="Fn3_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="SSF52279"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Fn3_like" evidence="3">
        <location>
            <begin position="624"/>
            <end position="693"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL74850.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="714" mass="78814" checksum="65C9C45023FFBE75" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMJ8</accession>
    <name>A0A0N8GMJ8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">LuxR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_12670</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75498.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063388.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000027.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12670"/>
    <dbReference type="EnsemblBacteria" id="KPL75498">
        <property type="protein sequence ID" value="KPL75498"/>
        <property type="gene ID" value="ADN00_12670"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1227"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="5"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="143"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="232"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL75498.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="353" mass="39591" checksum="56EEA30727FEC94B" modified="2016-01-20" version="1">MQTYRILLADDHVLIRAGLRDALTGLSNLEIVGEVGSGRELMQAIKTLTPDLLVMDVNMPDFEPVEAVERIRLLYPDLKILVVSAYDDQSYVIGLLSAGVNGYHLKDQPLSDLLLAVQRVLDGGRWISDPLVNRLVNHQTMINDSPAPSLTRRQRELLYLLTLGYNNHKIAHVMELSVKTVENHLTALYRALGVESRLEANNYASHHPELLAIPAQEKTAVGEEIAPSEDLTVLVVDDNPRYRAQMSRMLKKTHPSASLYEAEDTTEALRLARQIAPRLAFVDVVLREDDGIRCVRKLKQVSPTTRIILISAYPDREFRRIGLDAGAIAFLDKKDLDAATFRQLIEDSLEINC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GN31</accession>
    <name>A0A0N8GN31_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Peptide ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_10265</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76962.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062910.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10265"/>
    <dbReference type="EnsemblBacteria" id="KPL76962">
        <property type="protein sequence ID" value="KPL76962"/>
        <property type="gene ID" value="ADN00_10265"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2518"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045621">
        <property type="entry name" value="BPD_transp_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19300">
        <property type="entry name" value="BPD_transp_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="137"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="204"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="262"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="313"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="100"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL76962.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="340" mass="38501" checksum="3F18CD63552F24BA" modified="2016-01-20" version="1">MSSSLRNFLITRILLTIPMVLILITMVFFVMRVLPGDPIRSQLGPRVSEEKATQIRERLGLNRPLHEQYFSFLWDMVRLDFGNALTQGERPIRDELAERLPATMELTIPAMALTAVFGIFSGAYAAKNRKKPIDYLIRLFSIVIYSIPVFFLGLVFQIAFSVRLPLLPLSGRMDTLLLTSFDSPTNFYVLDAILTQNWPALRSALSHLVMPSVTLGLALTGVFIRLTRVNMIEMLQSDFITAGRARGLAEKRLVYRHALRNTFIPIMTLLGLQFAILLAGAVLTETTFSWPGMGRYLVERIQLRDYTAVQATIGVFALFVGLITLIMDVMYAFIDPRIRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNE4</accession>
    <name>A0A0N8GNE4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Beta-lactamase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_08285</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the N-terminal section; belongs to the zinc metallo-hydrolase group 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062516.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08285"/>
    <dbReference type="EnsemblBacteria" id="KPL77866">
        <property type="protein sequence ID" value="KPL77866"/>
        <property type="gene ID" value="ADN00_08285"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.659"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016440">
        <property type="entry name" value="Rubredoxin-O_OxRdtase"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005243">
        <property type="entry name" value="ROO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="2">
        <location>
            <begin position="256"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="400" mass="44811" checksum="9A0B3B35D30A4371" modified="2016-01-20" version="1">MKPVAIAPDTFWIGINDRTTDLFEGLWPIKKDGITYNTYLINDAKKAIIDLAKEFESIAFLEQIQHLVSLNEVDYVIINHMEPDHSGAVKALLAEAPQVKLVCSKKAAKMLVSYYGITENVQIVDDGDTLELGSHTLRFYSTPFVHWPETMMTFDETTGALFSCDGFGGYGAFRGSIFDEDTTDLDFYKTEALRYYVNIVATFSIPVSKAIQKLAEVPIKVVAPSHGLIWRKNPQEIIQLYSQWAAMQSTPGKNAVTMLYATMYGNTEKMMNAVAQGIAAENVPVEIFNVQYTHIGNLLPALWVNRAVAVGAPTYEKMLFPMMSNVIDMASIKRITDKEAIFFGSYGWAGTAKRDFLEKVTPLNWKMFETIDFEGSAGEMGLAQLEDLGKRFARYLLETN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNK3</accession>
    <name>A0A0N8GNK3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Lactamase_B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_07765</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062410.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07765"/>
    <dbReference type="EnsemblBacteria" id="KPL78338">
        <property type="protein sequence ID" value="KPL78338"/>
        <property type="gene ID" value="ADN00_07765"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="44"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="284" mass="31225" checksum="277D574A0964E400" modified="2016-01-20" version="1">MSKHFDLDLIRQMNSLKVGAGSLAVWGLGQMGVAVKTAGQKMVYIDPVLSNVVAETFPESAETFRRAFAAPVAAALVSNADVVMCTHDHLDHADPQTLREIAQASPRAVFIAPLWAASQLDEAGIPIERRIAPRVDQPLDVNGLRVWAVPAGHYDVEYDEKRGYRFLSYVLEADGVVFFHSGDTIIYPGYLERLKQLPKADIGLVAANGRDAFREAVGIVGNLLPEEAVQMARTLGWDVLLSGHNDLFEANTLPAGQMADALHRLNPRQKYHALQPGELYIYVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNP6</accession>
    <name>A0A0N8GNP6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ATP-dependent RecD-like DNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">recD2</name>
        <name evidence="3" type="ORF">ADN00_05370</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">DNA-dependent ATPase and ATP-dependent 5'-3' DNA helicase. Has no activity on blunt DNA or DNA with 3'-overhangs, requires at least 10 bases of 5'-ssDNA for helicase activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the RecD family. RecD-like subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="1"/>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061946.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05370"/>
    <dbReference type="EnsemblBacteria" id="KPL78682">
        <property type="protein sequence ID" value="KPL78682"/>
        <property type="gene ID" value="ADN00_05370"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1546"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043139">
        <property type="term" value="F:5'-3' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01488">
        <property type="entry name" value="RecD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006345">
        <property type="entry name" value="DNA_helicase_RecD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003583">
        <property type="entry name" value="Hlx-hairpin-Hlx_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029493">
        <property type="entry name" value="RecD-like_HHH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041451">
        <property type="entry name" value="RecD-like_SH13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027785">
        <property type="entry name" value="UvrD-like_helicase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14490">
        <property type="entry name" value="HHH_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18335">
        <property type="entry name" value="SH3_13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13538">
        <property type="entry name" value="UvrD_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00278">
        <property type="entry name" value="HhH1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01448">
        <property type="entry name" value="recD_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1 3" id="KW-0347">Helicase</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HhH1" evidence="2">
        <location>
            <begin position="131"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="HhH1" evidence="2">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="358"/>
            <end position="362"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="734" mass="81731" checksum="6A9AF71EC46ACEC1" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GPJ1</accession>
    <name>A0A0N8GPJ1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_00435</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL81042">
        <property type="protein sequence ID" value="KPL81042"/>
        <property type="gene ID" value="ADN00_00435"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="25"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="49"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="99"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="132"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="210"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="233"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="258"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="347"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="428"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="503"/>
            <end position="536"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL81042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="598" mass="66773" checksum="50DBC9290B015CA5" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WK10</accession>
    <name>A0A0P6WK10_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_18185</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL69997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064470.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18185"/>
    <dbReference type="EnsemblBacteria" id="KPL69997">
        <property type="protein sequence ID" value="KPL69997"/>
        <property type="gene ID" value="ADN00_18185"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2940"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014958">
        <property type="entry name" value="DGC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08859">
        <property type="entry name" value="DGC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL69997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="139" mass="15079" checksum="F0DF799366B06F6D" modified="2016-01-20" version="1">MSENKKVAIVPCSGIGKAFGTVSRVAAYQVVEDDRPEDTQLVPLALLVMGDEEHQEMLKEMPAITIDGCKLACATKMVQEAGGKVEKDFAVLEVFRRYRQFKPQGIAALNEDGEKLAAALAKEISEVVDEIVQKGAQDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WK15</accession>
    <name>A0A0P6WK15_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_18240</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the UPF0718 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064480.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18240"/>
    <dbReference type="EnsemblBacteria" id="KPL70006">
        <property type="protein sequence ID" value="KPL70006"/>
        <property type="gene ID" value="ADN00_18240"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2952"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005524">
        <property type="entry name" value="DUF318"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03773">
        <property type="entry name" value="ArsP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="61"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="98"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="129"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="173"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="221"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="252"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="281"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="322"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="352"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="391"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="419"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006386"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL70006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="443" mass="47865" checksum="7DCE8B7DF4CE1795" modified="2016-01-20" version="1">MNPTLEYLGMLLWSGWTGLLDYLAAHVLLCLVPAFVIAGFMSSMIPKEAITRFLGPKASKWISYPASAFGGFILAVCSCTILPLFAGIWKRGAGLGPAITFLFVGPAINILAISYTGAAIGFDIAASRLILSIVFGIVIGLIIAWVFRKEESQRSADMAANGLFDQQVKVNPAVWVMFVLLVAVLIVGTLQVGLLTNVYARITLPFDLPEGLMNLFSSLNITLQGALLILMLVVIGVTSWKGFENIFEGFTKWTYIAIGVIAMTVLIAAPKEEVGSIIIGINGRLIGEVILLAAIAFVGSRSFTKDELGGWIWETWKFVKQIFPLLIVGVFAAGIVRVIIPEEWVRTIAGQNTIWANLVGVLFGVFMYFPTLVEVPIAKMFLDLGMARGPLLAYLLSDPELSLQSILVLNGVMGKKKTAIYVGLVAIFSTMAGYLFGVVLAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WMS0</accession>
    <name>A0A0P6WMS0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_18850</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064589.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70103">
        <property type="protein sequence ID" value="KPL70103"/>
        <property type="gene ID" value="ADN00_18850"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="75" mass="8544" checksum="9CF6414D1E993E3A" modified="2016-01-20" version="1">MASFIGTKKKIYCPKCQHVVGDVVIIENREWLKVNGIAVNVMRGVCLECGAEFHWSISERMLSQLVEHVIKLRDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WMV7</accession>
    <name>A0A0P6WMV7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_19140</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064642.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70149">
        <property type="protein sequence ID" value="KPL70149"/>
        <property type="gene ID" value="ADN00_19140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="252" mass="28398" checksum="2D0260050C1019D4" modified="2016-01-20" version="1">MATQSIPFSTVSKDEYAHQLYSHALDHQFTEPSSALLALMNLIEQFPETWTVQYLVIDAALEIALKFGFYTEALEICRRAQEIDRRCAEIYRLEAEAIQLELENRIVEATKKRLEKDVARGKCFGTLQKYAETMIQLGDFDAAGRLLDEAAQIAQSEGLMLFDIMRSRAVLLRRQGRTVEAVEHLIDAFANAADWKVAAAPFSLVRELDVTLREIHLADGDLAQWLAQAGMEGAVDDAKQAFRAALWEKSCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WQF8</accession>
    <name>A0A0P6WQF8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FeS_assembly_P domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_15330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15330"/>
    <dbReference type="EnsemblBacteria" id="KPL72292">
        <property type="protein sequence ID" value="KPL72292"/>
        <property type="gene ID" value="ADN00_15330"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002744">
        <property type="entry name" value="MIP18-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01883">
        <property type="entry name" value="FeS_assembly_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="SSF117916"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FeS_assembly_P" evidence="1">
        <location>
            <begin position="4"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="91" mass="10472" checksum="773EC225FD787C20" modified="2016-01-20" version="1">MQDKLREVVDPEIGMDMIQLGLVRNLMIGEKKAHVVMILTTPFCPYGPSLIENVRAKTEEVVNLPTTIELGDEMWDYDMMEEGSEPEWGMW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-04-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WSQ8</accession>
    <name>A0A0P6WSQ8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Xylulose kinase</fullName>
            <shortName evidence="3 5">Xylulokinase</shortName>
            <ecNumber evidence="3 5">2.7.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">xylB</name>
        <name evidence="8" type="ORF">ADN00_16230</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the phosphorylation of D-xylulose to D-xylulose 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 5">
            <text>ATP + D-xylulose = ADP + D-xylulose 5-phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10964"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17140"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57737"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.17"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the FGGY kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.17" evidence="3 5"/>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064089.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72032">
        <property type="protein sequence ID" value="KPL72032"/>
        <property type="gene ID" value="ADN00_16230"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3683"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004856">
        <property type="term" value="F:xylulokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042732">
        <property type="term" value="P:D-xylose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005998">
        <property type="term" value="P:xylulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02220">
        <property type="entry name" value="XylB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000577">
        <property type="entry name" value="Carb_kinase_FGGY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="Carb_kinase_FGGY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018483">
        <property type="entry name" value="Carb_kinase_FGGY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018484">
        <property type="entry name" value="Carb_kinase_FGGY_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006000">
        <property type="entry name" value="Xylulokinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02782">
        <property type="entry name" value="FGGY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00370">
        <property type="entry name" value="FGGY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000538">
        <property type="entry name" value="GlpK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01312">
        <property type="entry name" value="XylB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00445">
        <property type="entry name" value="FGGY_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 3 5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0808">Transferase</keyword>
    <keyword evidence="1 3 5" id="KW-0859">Xylose metabolism</keyword>
    <feature type="domain" description="FGGY_N" evidence="6">
        <location>
            <begin position="4"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="FGGY_C" evidence="7">
        <location>
            <begin position="259"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="83"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="242"/>
        </location>
    </feature>
    <feature type="site" description="Important for activity" evidence="3">
        <location>
            <position position="9"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022629"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU364073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL72032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="501" mass="54641" checksum="5ED35F4D6DCFE40B" modified="2016-01-20" version="1">MSSYFLGVDLGTSSLKTILLDAESGSLLAQVAAEYSIQTPQPGWAEQDPQIWVDAFLSTLPVVMSQARIDASQIEGISFSGQMHGCVCLDAQGNPLRPAIIWADQRSARQVEQVYTCQGIEKLGAATGNPLAAGFMLPTLLWLRENEAEVYTRIHQVMLPKDYLRLVITGEYGSEPSDASSTGLFDPARQDWNEDWLTGLAIPLRFLPPVKPSHAPGGSVSKPFAILSGLRAGTPVFMGASDQSAQALGNGIIQPGDVSCTIGTGGQILAPVLQPRYDPQLRLHLFCHALPQVWHLESATLSAGLSLKWLRDHFFEDRSYQQLVDEAAHAPVGAEGLRYLPYLAGERTPIMDPLATGSFTGLTLRHHRRHLVRAVLEGVVFSLRQGLDLMQTLGAPIQRIVASGGGTRHPLWLQLQADIFARPIYQSSTPEAAALGAALLAAVGSGYYASFEQACQHIVHWKPAAIEPIENNVRLYEEIYPHYCSLYPTLRATFNRKSGNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WT28</accession>
    <name>A0A0P6WT28_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_18370</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064506.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70029">
        <property type="protein sequence ID" value="KPL70029"/>
        <property type="gene ID" value="ADN00_18370"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="238"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="268" mass="29741" checksum="F9EFA0DF2A17EB73" modified="2016-01-20" version="1">MSQRKPVDFSPWHELQRMSRSAWFLVLTILLGAIGGGLVHQFIPPFYEARSVMTVLIDYTRTGYLEDYQQDQIMEAVGDLVAATDVKQQAAELAGWPQEEIQSGAYLEHFFVERQYFKWIMRVRSANAELAAAAANAWADETARSINEGLEHAILAGGLERYQYALEKCLEQIALVEPVQAYCSVNNLAELQSELESSAKVLRDERVLSKGLIPAITYEVNEKAVVPNAPVARGRNTLILAGMAVGLGLGVLGLAVDLPARLLRRREP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WV36</accession>
    <name>A0A0P6WV36_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_14045</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063658.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000033.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74120">
        <property type="protein sequence ID" value="KPL74120"/>
        <property type="gene ID" value="ADN00_14045"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL74120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="107" mass="12354" checksum="00C54C263A02F4A8" modified="2016-01-20" version="1">MTNERDLENLDVHFKNPPEIPAEWIDLMTQLHPITAVVIWEVMTGNLSPASLRLARYSPDRERYTSIAIIAGGNPDFCSELAEMARQDLDEIFQDLLPEYRPYQVLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WW05</accession>
    <name>A0A0P6WW05_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Pyruvate kinase</fullName>
            <ecNumber evidence="3 11">2.7.1.40</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">ADN00_19155</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + pyruvate = ADP + H(+) + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:18157"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.40"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 11">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the pyruvate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.40" evidence="3 11"/>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_19155"/>
    <dbReference type="EnsemblBacteria" id="KPL70151">
        <property type="protein sequence ID" value="KPL70151"/>
        <property type="gene ID" value="ADN00_19155"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3143"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00188"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030955">
        <property type="term" value="F:potassium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004743">
        <property type="term" value="F:pyruvate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.33.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001697">
        <property type="entry name" value="Pyr_Knase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015793">
        <property type="entry name" value="Pyrv_Knase_brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015806">
        <property type="entry name" value="Pyrv_Knase_insert_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11817">
        <property type="entry name" value="PTHR11817"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00224">
        <property type="entry name" value="PK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01050">
        <property type="entry name" value="PYRUVTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="SSF50800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="6 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PK" evidence="12">
        <location>
            <begin position="1"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KPL70151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="303" mass="33138" checksum="80FF92C55326DB59" modified="2016-01-20" version="1">MLAAGVDAFRLNTSHLSIAQLNTWLDQIQSFTRALDPHPPLVLDLQGSKWRLGQFPTFDLEPGQKVQLVFATASQAKNVLPVPHADFFSAASLSSGEIVLNDAKTRLQLESITPEAVTATVLLGGTIASNKGITFSASDYRIEALNAKDQAIIDQTHRLGFIRYAISYIKDAAEMAQYRALMGASSHLIAKLERQPAVSEAAQISESADELWLCRGDLGAELGMRAMAEAVHEFSLHLREYAVPVYMAGQILEHMTLHPTPTRSEVCFLHDTVKKGFRGVVLSDETAIGQYPIEACQTSALFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WX54</accession>
    <name>A0A0P6WX54_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_17970</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000044">
        <property type="protein sequence ID" value="KPL70764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064426.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000044.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70764">
        <property type="protein sequence ID" value="KPL70764"/>
        <property type="gene ID" value="ADN00_17970"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="131" mass="14626" checksum="0AAA3B47C3B00CC5" modified="2016-01-20" version="1">MKFFHKLFKEDATQKTSVSKEVTKVESPNPMLPKVQGILVLSRHPMGQPAVSALFQQILDAQKLQGHGFAEGCVAHHMVADQSIDDQTYVAGAILRVFSSFGEDVLNRTKKFPYQIPGGDSGKFFVLYDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WY64</accession>
    <name>A0A0P6WY64_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH araC/xylS-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_16740</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064197.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16740"/>
    <dbReference type="EnsemblBacteria" id="KPL71355">
        <property type="protein sequence ID" value="KPL71355"/>
        <property type="gene ID" value="ADN00_16740"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.406"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010499">
        <property type="entry name" value="AraC_E-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029442">
        <property type="entry name" value="GyrI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011256">
        <property type="entry name" value="Reg_factor_effector_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06445">
        <property type="entry name" value="GyrI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00871">
        <property type="entry name" value="AraC_E_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55136">
        <property type="entry name" value="SSF55136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="2">
        <location>
            <begin position="15"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL71355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="291" mass="32834" checksum="1B51E7ADF4E600AF" modified="2016-01-20" version="1">MNQSAPRDEYDQRIRQVMDYVNRHLDQPLLLDSLAGEAGFSPYHFHRIFSAMVGETPADYVNRLRLERAANLLLKSEQPVTEIALACGFSSPAVFARGFKQRFGVTASQYRRDRGQSSRMGVHPMAQPEQHLPVLDVRVRELAVVPVIYVASMEGYKREKICAAWLRLQKWASVRGLISEQTRSIGLSFDDPAITPANRCQYFACLSVPHKVVTNQRIGYMEIAGGLYAVGRATCSREGIRWVYATLFGEWLPSSGFQPAVQPPYEVYLQTPETHPQGLFEIEVCIPVVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZM4</accession>
    <name>A0A0P6WZM4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Isopentenyl-diphosphate delta-isomerase</fullName>
            <shortName evidence="6">IPP isomerase</shortName>
            <ecNumber evidence="6">5.3.3.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Isopentenyl diphosphate:dimethylallyl diphosphate isomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Isopentenyl pyrophosphate isomerase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Type 2 isopentenyl diphosphate isomerase</fullName>
            <shortName evidence="6">IDI-2</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">fni</name>
        <name evidence="8" type="ORF">ADN00_15305</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in the biosynthesis of isoprenoids. Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its allylic isomer, dimethylallyl diphosphate (DMAPP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>isopentenyl diphosphate = dimethylallyl diphosphate</text>
            <dbReference type="Rhea" id="RHEA:23284"/>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
            <dbReference type="ChEBI" id="CHEBI:128769"/>
            <dbReference type="EC" id="5.3.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>NADPH</name>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5 6">Homooctamer. Dimer of tetramers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the IPP isomerase type 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.3.2" evidence="6"/>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72291.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064010.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15305"/>
    <dbReference type="EnsemblBacteria" id="KPL72291">
        <property type="protein sequence ID" value="KPL72291"/>
        <property type="gene ID" value="ADN00_15305"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.763"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004452">
        <property type="term" value="F:isopentenyl-diphosphate delta-isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070402">
        <property type="term" value="F:NADPH binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02811">
        <property type="entry name" value="IDI-2_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00354">
        <property type="entry name" value="Idi_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000262">
        <property type="entry name" value="FMN-dep_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011179">
        <property type="entry name" value="IPdP_isomerase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43665">
        <property type="entry name" value="PTHR43665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01070">
        <property type="entry name" value="FMN_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003314">
        <property type="entry name" value="IPP_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02151">
        <property type="entry name" value="IPP_isom_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6" id="KW-0288">FMN</keyword>
    <keyword evidence="6 8" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 6" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0521">NADP</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN_dh" evidence="7">
        <location>
            <begin position="171"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="4"/>
            <end position="5"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="92"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="61"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="62"/>
            <end position="64"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="187"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="217"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="267"/>
            <end position="269"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="288"/>
            <end position="289"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025810"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01070"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL72291.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="341" mass="36385" checksum="5C215F605E88DCE2" modified="2016-01-20" version="1">MSNRKADHIRINLAEDVSSSRTNGLEEYQFTHCALPEIDFQHIQTAQECFGRELALPILISSMTGGTDEAARINSDLAEVAQACGLAMGVGSQRVGLRDAKTQDSFRVRKIAPSILLFANIGAVQLNYGYQVDDCRRVVEMIEADALYLHLNPLQEALQPEGDTNFSGLLKKIEAVCRALAVPVFVKEVGWGISGQVAAQLARAGVSGIDVAGAGGTSWSEVEKHRMTDPIRAKVAGAFRGWGISTAASLVQVKESAPDLFLIASGGLRSGMDIAKCIALGALAGGLAGPFLKAIVQSQQTAMKLVEELSLELRVCMFAAGAQDIQSLQNTPLMKIDKGML</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X0M7</accession>
    <name>A0A0P6X0M7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Phosphofructokinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ADN00_13635</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74382.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13635"/>
    <dbReference type="EnsemblBacteria" id="KPL74382">
        <property type="protein sequence ID" value="KPL74382"/>
        <property type="gene ID" value="ADN00_13635"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1303"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00182"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003872">
        <property type="term" value="F:6-phosphofructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022953">
        <property type="entry name" value="ATP_PFK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012003">
        <property type="entry name" value="ATP_PFK_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000023">
        <property type="entry name" value="Phosphofructokinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035966">
        <property type="entry name" value="PKF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00365">
        <property type="entry name" value="PFK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000532">
        <property type="entry name" value="ATP_PFK_prok"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00476">
        <property type="entry name" value="PHFRCTKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53784">
        <property type="entry name" value="SSF53784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="6 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PFK" evidence="9">
        <location>
            <begin position="2"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL74382.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="369" mass="41075" checksum="3C2C5749511197DF" modified="2016-01-20" version="1">MKSVVMSALENDYRVIGIRRGWAGLLHYNLDEHSTHDYYVKDLSLHDVHRIDRTGGTFLHTSRTNPQRVKPQDVPDFLKNSAYGKAIDDKGTMDYTDYIMKVLSHLGIDILVTIGGDDTLSYSVRLHKEGFPVVAIPKTMDNDVFGTDYCIGFSTAITRSVDFITNMRTSVGSHERIGVVELFGRNAGETSLIAGYLAYVDRVLIPEVPFNMERLAGYIMEDKRNNPSNYAILTISEGAIMEAGSIIESGEEDAYGHRKLGGIGEVVAEEIKRLTGQGIMYQQLGYLMRSGAPDSLDRMVAMSFGHLAIQLIQRNDFGKLTALHGGKYTTVPVEMVLSGKKVVDVKSFYDISTYKPFIKDFLGVPMFLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X1A1</accession>
    <name>A0A0P6X1A1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">50S ribosomal protein L17</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rplQ</name>
        <name evidence="6" type="ORF">ADN00_12465</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit. Contacts protein L32.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the bacterial ribosomal protein bL17 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063343.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12465"/>
    <dbReference type="EnsemblBacteria" id="KPL76141">
        <property type="protein sequence ID" value="KPL76141"/>
        <property type="gene ID" value="ADN00_12465"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3974"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1030.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01368">
        <property type="entry name" value="Ribosomal_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000456">
        <property type="entry name" value="Ribosomal_L17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036373">
        <property type="entry name" value="Ribosomal_L17_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14413">
        <property type="entry name" value="PTHR14413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01196">
        <property type="entry name" value="Ribosomal_L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64263">
        <property type="entry name" value="SSF64263"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00059">
        <property type="entry name" value="L17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000660"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL76141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="125" mass="14269" checksum="CAEF63BF7E0C6C4E" modified="2016-01-20" version="1">MRHQVAGYKLSRSKDQRNALRRTLINQLFTHEKIQTTRAKAMAIRGDAEKLITLARNAEKASDVEKVNARRLAASRLENATVVKKLFEDIGPRFANRNGGYTRMFRLGLRQGDSAEMVRLELVED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X1F2</accession>
    <name>A0A0P6X1F2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L13</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rplM</name>
        <name evidence="5" type="ORF">ADN00_12455</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">This protein is one of the early assembly proteins of the 50S ribosomal subunit, although it is not seen to bind rRNA by itself. It is important during the early stages of 50S assembly.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL13 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063341.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12455"/>
    <dbReference type="EnsemblBacteria" id="KPL76177">
        <property type="protein sequence ID" value="KPL76177"/>
        <property type="gene ID" value="ADN00_12455"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3972"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00392">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01366">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005822">
        <property type="entry name" value="Ribosomal_L13"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005823">
        <property type="entry name" value="Ribosomal_L13_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036899">
        <property type="entry name" value="Ribosomal_L13_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11545">
        <property type="entry name" value="PTHR11545"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00572">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002181">
        <property type="entry name" value="Ribosomal_L13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52161">
        <property type="entry name" value="SSF52161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01066">
        <property type="entry name" value="rplM_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL76177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="144" mass="16194" checksum="B3B400DA437D717B" modified="2016-01-20" version="1">MVNVEKTYVIKGKTEPNWLLVDAEGQNVGRLATQIASYLLGKHKPTFTPGVDMGDIVVVINVDKLSIAQKRLENKMYYRHSNFPGGLTATSMKDQMVQHSDRVIRHAVWGMLPHNSLGRKLLKRLKIYAGNEHPHEAQNPQPVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X2Z4</accession>
    <name>A0A0P6X2Z4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Ribulose 5-phosphate epimerase</fullName>
            <ecNumber evidence="2">5.1.3.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_14400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.4" evidence="2"/>
    <dbReference type="EMBL" id="LGCL01000034">
        <property type="protein sequence ID" value="KPL73772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063748.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000034.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14400"/>
    <dbReference type="EnsemblBacteria" id="KPL73772">
        <property type="protein sequence ID" value="KPL73772"/>
        <property type="gene ID" value="ADN00_14400"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1399"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008742">
        <property type="term" value="F:L-ribulose-phosphate 4-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.225.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001303">
        <property type="entry name" value="Aldolase_II/adducin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036409">
        <property type="entry name" value="Aldolase_II/adducin_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00596">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01007">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53639">
        <property type="entry name" value="SSF53639"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldolase_II" evidence="1">
        <location>
            <begin position="7"/>
            <end position="183"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL73772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="214" mass="23046" checksum="20875A0E3DD58038" modified="2016-01-20" version="1">MLQALREEVYKCNMLLPENDLVKMTSGNVSGRDPQTNLVVIKPSGVAYEKLSPENMVIVDLDGNVVEGDLTPSIDTETHLVVYRARPDVFGMVHTHSTYATSFAVLGQPIPPVTTTCGLIGGGVPLGRFACFGGETIGHEVVNVIGDSYAVIMQSHGVFTIGHSASHATRVAVEVEEMAKIAHLAMLRGKPIILTPEQIREVSSGYVNDYGQKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X358</accession>
    <name>A0A0P6X358_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DNA mismatch repair protein MutS</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_08995</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062663.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08995"/>
    <dbReference type="EnsemblBacteria" id="KPL77265">
        <property type="protein sequence ID" value="KPL77265"/>
        <property type="gene ID" value="ADN00_08995"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4033"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030983">
        <property type="term" value="F:mismatched DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS_family"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="PTHR11361"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_MISMATCH_REPAIR_2" evidence="3">
        <location>
            <begin position="330"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL77265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="511" mass="59331" checksum="83E18AF37CFAC67C" modified="2016-01-20" version="1">MTFQSILFEQQPDHTQIGSAIMPPYFPDLNLDQVIDAIVFGRREYNLRPFFYSPLKDVETVRYRQEVARDLENNSVFESIKTFAEKMIMMRRYLGLVEKLEFHYHREGWFLEAALVYCEAVSDLAEDLSRAPIKSRGFIAFREYLNNYVHSPYYHTLRTETEQRKAALSTIRYTLIIKDRKIIVRRYQSEINYSREVERTFEKFKQGAVKDYRSKLRKASGMNHVEGQILDYVARLHPEPFADLDQYCKMHQNFLDETIRVFDQEVQFYVAYLEFIQKIKLAGLKFCYPEVSAVSKEISEVDGFDIALANKLTGENAAVICNDIFLTGKERIIIVSGPNQGGKTTFARMFGQIHYLGSLGLPVPGRHARLFLFDNLFTHFEKEENIQNLRGKLQDDLVRMHKILKQATPASIVIMNEVFTSTTLKDAVYLSNKVMEKIIQLDLLCVCVTFLDELASLNGKTVSMVSTIVPKNPALRTFKVIRRRADGLAYALNIAEKYHLTHDLLKERIKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X3U5</accession>
    <name>A0A0P6X3U5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PlsC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_08680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000022">
        <property type="protein sequence ID" value="KPL77659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062601.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000022.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08680"/>
    <dbReference type="EnsemblBacteria" id="KPL77659">
        <property type="protein sequence ID" value="KPL77659"/>
        <property type="gene ID" value="ADN00_08680"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PlsC" evidence="1">
        <location>
            <begin position="34"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="231" mass="25681" checksum="6E60EEFE3B6A7069" modified="2016-01-20" version="1">MKRETLVKIFKFLFKHLTRLSYEGMENIPAVGGVIIATNHMSRLDFPALFMVSSREDITALVADKYQSYVLFNFIIRTAGGIYLDRSKADFSAFSTGVDFLRKGGALGIAPEGTRSKVGALLEGKPGAVLLATRAKVPVVPVAVTGTEVSVKQLLRLRRPKIHVRVGPAFTYPPLDRDQRHDLLKKYTDEVMCRIAAMMPESYHGFYTGHPRIKEIQAELAAAHQSEPVHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X3X9</accession>
    <name>A0A0P6X3X9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">N-acetylneuraminate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_12055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063266.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12055"/>
    <dbReference type="EnsemblBacteria" id="KPL76073">
        <property type="protein sequence ID" value="KPL76073"/>
        <property type="gene ID" value="ADN00_12055"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3887"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016051">
        <property type="term" value="P:carbohydrate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006190">
        <property type="entry name" value="AFP_Neu5c_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036732">
        <property type="entry name" value="AFP_Neu5c_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013132">
        <property type="entry name" value="Neu5Ac_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013974">
        <property type="entry name" value="SAF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03102">
        <property type="entry name" value="NeuB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08666">
        <property type="entry name" value="SAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00858">
        <property type="entry name" value="SAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51269">
        <property type="entry name" value="SSF51269"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50844">
        <property type="entry name" value="AFP_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AFP-like" evidence="1">
        <location>
            <begin position="296"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="355" mass="39545" checksum="5A0570083EC07D4B" modified="2016-01-20" version="1">MEIRIGKNLVGENHPTYFIADIAANHDGDLNRARLLIRLAKEAGADAAKFQNFQAEKIVSDYGFSHMNAQVSHQASWKKSVVQVYREASVPFNWTAALKTACDEVGIDYFSSPYDFEAIDMLDEYVPAYKIGSGDIDWLESIEYMARKGKPVLLATGASNIGEVQRAVHAALRVNPQLVLMQCNTNYTASLENFDHIHLRVLETYRSMFPNVILGLSDHTPGHATVLGAVALGARVIEKHFTDDNNREGPDHKFAMNPQTWADMVENTRRLERALGSADKVIAGNEQQTAIVQRRCLRAARDIRAGEPFTREMIDVLRPATPGAIKPSEVEAVLGTRAIEDIPAGKELRWTMLRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X436</accession>
    <name>A0A0P6X436_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">AraC family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_07915</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062449.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07915"/>
    <dbReference type="EnsemblBacteria" id="KPL77805">
        <property type="protein sequence ID" value="KPL77805"/>
        <property type="gene ID" value="ADN00_07915"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.583"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010499">
        <property type="entry name" value="AraC_E-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029442">
        <property type="entry name" value="GyrI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018060">
        <property type="entry name" value="HTH_AraC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018062">
        <property type="entry name" value="HTH_AraC-typ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011256">
        <property type="entry name" value="Reg_factor_effector_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020449">
        <property type="entry name" value="Tscrpt_reg_HTH_AraC-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06445">
        <property type="entry name" value="GyrI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12833">
        <property type="entry name" value="HTH_18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00032">
        <property type="entry name" value="HTHARAC"/>
    </dbReference>
    <dbReference type="SMART" id="SM00871">
        <property type="entry name" value="AraC_E_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00342">
        <property type="entry name" value="HTH_ARAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55136">
        <property type="entry name" value="SSF55136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00041">
        <property type="entry name" value="HTH_ARAC_FAMILY_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01124">
        <property type="entry name" value="HTH_ARAC_FAMILY_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH araC/xylS-type" evidence="2">
        <location>
            <begin position="8"/>
            <end position="106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS01124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="290" mass="32954" checksum="170555107096E2A8" modified="2016-01-20" version="1">MDSIKAMNEAIRYIEENLTGEIQMKEIARLAICSEYHFQHMFSFLAGISLNEYIRRRRLTLAAFELSQSDLRVLDIAVKYGYSSADAFARAFQAFHGVLPSEARKKGIPLKAFPRLTFQLTITGGIEMNFRIVEKAAFRIVGLQKRVRIQFNGVNAEIAEMWNSLTPDMITQLKAMSNVEPVGMISASTHFSEGRMQEQGELDHFIGVTTDKACPDHFQSLEVSSSTWAVFEAVGPFPETLQNVWGRIYSEWFPSSNYELAPGPEILWNESKDVSLPNYRSEIWIPVQPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X489</accession>
    <name>A0A0P6X489_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_08410</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08410"/>
    <dbReference type="EnsemblBacteria" id="KPL77887">
        <property type="protein sequence ID" value="KPL77887"/>
        <property type="gene ID" value="ADN00_08410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132821" evidence="2">
        <location>
            <begin position="27"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="45"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="359" mass="39387" checksum="FCE51803F36C875B" modified="2016-01-20" version="1">MIEKRTQKTSFLLIFALFLVLLSACGTPQETPVATCQPTEAPTSTPTRTPWPSPTPTPTSTPTPRPPGAEDMPFKMGVVLSPIDQNALTASGVLSQYLFEQTGLAFQVEYYERYEDLLHDLGDYSLHAAWLPPLTYVYAQQEELAEVNLLVNNYGTYAIGVQFLAPKSSGVQVSFNAEKNINTANAATALRQFQGKTPCWVSRTSASGYVVPAAILEQNSIPVQPGAMLQSHSAVIRALYAGGICDFGATFSISGDPRTAPDLLAEHPDILEEIPIIWRSDPIIPNLNLSYHPYIQDDLRSMINVALFNFISSPEGQQTLTNTLQYNVQDLKWVEDDLYQPLTELLEILGDDIASFIGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X4K8</accession>
    <name>A0A0P6X4K8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aminotran_1_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_11520</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 2">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063161.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11520"/>
    <dbReference type="EnsemblBacteria" id="KPL76576">
        <property type="protein sequence ID" value="KPL76576"/>
        <property type="gene ID" value="ADN00_11520"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001917">
        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00599">
        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="3">
        <location>
            <begin position="36"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL76576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="368" mass="41060" checksum="C9541F0D9FD78E60" modified="2016-01-20" version="1">MEFKPLVNPRIFDVPDYDQHHVTQCWEDASIHRAMSNESNYAPIPAVQQAIIEAASQANYYAEDPSYALALRSKLAAYSAVKPENITLGNGSIEVLDLLFQIFIAKPGEDECVLVQPDYSAYTPRIKYFGGVIKYADTDANFVPDADAIIAQITPKTKFVLFSRPNNPMGTVMPKEDVRRILETGVVTFVDEAYVEMADDGTSVSPWLSEFDNLVVLRTFSKGFSLAGIRLGYVIAHPELIRYVNRSRHIFNVNLAAMAAGNAALDHMDEVRQIFKKLAETRDWMTEEIAKIPGLKPIPSKGNFVMINVKETGKTGTDFVNHLMGKGYMVRDFSKKAGLEPGAHFRISVGLPEVMMNLLGEIKLYLNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X509</accession>
    <name>A0A0P6X509_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76915.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76915">
        <property type="protein sequence ID" value="KPL76915"/>
        <property type="gene ID" value="ADN00_09970"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="275"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76915.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="303" mass="32490" checksum="5152FB7CF620FF1F" modified="2016-01-20" version="1">MAGFGIRIIGQNGWTKSVKIEKAITRVGSAPSCDLQIQAPEVSPEHLQLFFLQESPATCQVLNLGAGVLFRQGGQSAADLPAYAVASAQNGDEIWLGDYRIQFDLPLSNRSVQTSQVVEATLEFPNAILRPDLVTAGRIFIRHVGPQPTCQFQVTLSGLPAGCVQVDPLPLLFSGGAGEAGVRLFHRGQSPRAGFHDLTITITAPETYPGEQAVLQQRVYVSPVFEQSLELQDDLAGARLAQPTVMVEPPPAAPQVTLPAEPDILPTAWEAAAIPAPQPVRVGEPAPKPKLVRNPSENFWDGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X522</accession>
    <name>A0A0P6X522_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062887.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76942">
        <property type="protein sequence ID" value="KPL76942"/>
        <property type="gene ID" value="ADN00_10145"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="148" mass="15506" checksum="440EDC65BB138664" modified="2016-01-20" version="1">MQKKNTFTKILAAAGCVLIWLPLAAPVMFTAIRLAQGGPFRFDFLMPGELFPAALAGALLLLWAALRVRSQVRIIAWGLGCMVALLVGSQGLAVVSGLASGRIEASGPWFVLVLTLFVGFILAMVVIAVSGVRLARGLFARPAADGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X582</accession>
    <name>A0A0P6X582_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_10520</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062956.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10520"/>
    <dbReference type="EnsemblBacteria" id="KPL76997">
        <property type="protein sequence ID" value="KPL76997"/>
        <property type="gene ID" value="ADN00_10520"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2575"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024524">
        <property type="entry name" value="DUF3800"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12686">
        <property type="entry name" value="DUF3800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="235" mass="27891" checksum="042F8D02930A6370" modified="2016-01-20" version="1">MSKIYNIYCDESCYLQNDISRVMVIGAIWCPKSQVKEINNDLRLIKTEHGFPVTFETKWIKVSPAQLVFYQELVNYFFSNNHLHFRALIVPDKSKLRHEDYNQTHDDWYYKMYFDMLKIIFDPENQYQIYVDIKDTRSAIKVAKLHDVLCNNLFDFSRDIIEKVQIVRSNEIEIMQLTDLFIGAICYANRGLTTSQAKLSLIELIRRKSGYKLTEKTLFRADKINLFKWNAQENG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5B2</accession>
    <name>A0A0P6X5B2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ABC transmembrane type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_10815</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063010.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10815"/>
    <dbReference type="EnsemblBacteria" id="KPL77043">
        <property type="protein sequence ID" value="KPL77043"/>
        <property type="gene ID" value="ADN00_10815"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2641"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045621">
        <property type="entry name" value="BPD_transp_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19300">
        <property type="entry name" value="BPD_transp_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="9"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="125"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="158"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="215"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="274"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="319"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="123"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL77043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="352" mass="39225" checksum="0EA0637A68D34700" modified="2016-01-20" version="1">MGRYIVRRLLYMVVVLFVVSAITFGLMHAVPGGPFDREKALPPEIMANLEKRYHLDDPLLVQYGNYLYDVFIPQFSTTAPTLSIEDDALLKFNVGGIYVNWMNFGPSFSSRSRTVNDIFRDQLPISIQLGILALLVAIIIGMPLGILSALKQNTIFDYLGMSVAIFGVSVPVIVLGPILIWIFGVLLKVLPPTGWGTKPPFLLGFLPTDYSWEGFWKYTIMPAIALGLGSSAIIARLTRASLLQVVREDYIRTARAKGLRENLVITRHALKNSLIPVVTILGPMFAALVTGTFVTELTFGIPGMGRYFVTSITNRDYPVIMGTILLYAFFLVIANLIVDMVYAYLDPRIRYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5C7</accession>
    <name>A0A0P6X5C7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">WYL domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10930</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063032.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10930"/>
    <dbReference type="EnsemblBacteria" id="KPL77061">
        <property type="protein sequence ID" value="KPL77061"/>
        <property type="gene ID" value="ADN00_10930"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026881">
        <property type="entry name" value="WYL_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13280">
        <property type="entry name" value="WYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WYL" evidence="1">
        <location>
            <begin position="165"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="358" mass="40794" checksum="D286BECAFFE1DACC" modified="2016-01-20" version="1">MPPRGARGSDWMVVRRCLALVARLQRGPASPQELVQAVCDALGPDAYPPDPSARAAAFKHDRDHLRQHLDADFVYDPAARQYALTQAGPFGRLHLSDSALRAVRLLSEAFTGQMGARQEVQALLQELTTRLSPADQRRLETLNSAVDLDLQQDVDRGSIPEVVWQTVERAVRVQRKLCFNYISPRHEDRLPRYHEAAPAQMRFQRGHWYLYAFDLYSRDPYGEERFDSGYKNFRVQYICADEKLIISPTRLPGVARTPPRYEVHYRLEPRLARGQISHHFENTHITRLPDGRAEITATTDNLWEAAQVLLSYSDGCEVLGCPELRQMMVDRTRGMAAIYGLDVENRSKLADLPTNTDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X6W4</accession>
    <name>A0A0P6X6W4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NMT1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_08790</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000022">
        <property type="protein sequence ID" value="KPL77673.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08790"/>
    <dbReference type="EnsemblBacteria" id="KPL77673">
        <property type="protein sequence ID" value="KPL77673"/>
        <property type="gene ID" value="ADN00_08790"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1476"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027939">
        <property type="entry name" value="NMT1/THI5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015168">
        <property type="entry name" value="SsuA/THI5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31528">
        <property type="entry name" value="PTHR31528"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09084">
        <property type="entry name" value="NMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132880" description="NMT1 domain-containing protein" evidence="1">
        <location>
            <begin position="26"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="domain" description="NMT1" evidence="2">
        <location>
            <begin position="45"/>
            <end position="256"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77673.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="331" mass="35755" checksum="CBA6E3FB7F1FE1C7" modified="2016-01-20" version="1">MKQRIIFSIVIISLLLAACAPQAPASAPASQELTAIRLPVGYIPNVQFAPLYVAMEKGYFKEAGLEVTLDYSFETDAVALVGANELPFSIASGEQVLLGRAQDLPVVYVYTWYGEYPVGIASLAEAGIVKPEDLRGRKIGTPVLYGASYIGFRALLQAGGLKESDVTLDVIGFNQVEALSSGQVDAVVIYVPNEPVQLANQGYKLNVIRTADYLPLVGNGLITNEKTIAENPELVRRMAGALQKGVADTLADPDAAYEICKKYVENLTEADEAAQKQVLKTSLEFYQTEPLGQSAPQAWENMQNILLTMGLLAGDQDLSQAWSNAFVTETK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X708</accession>
    <name>A0A0P6X708_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_17965</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000044">
        <property type="protein sequence ID" value="KPL70763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064425.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000044.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70763">
        <property type="protein sequence ID" value="KPL70763"/>
        <property type="gene ID" value="ADN00_17965"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="76" mass="8811" checksum="F073BF3E64C4959C" modified="2016-01-20" version="1">MPKKNSPTKPVRSFRLSLECVRQLKDLAGNMARSEGDVIEISIDRMYREELRFGNLTIGEGENPEDNYKVDQHEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X730</accession>
    <name>A0A0P6X730_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutamate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_12320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063315.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12320"/>
    <dbReference type="EnsemblBacteria" id="KPL76118">
        <property type="protein sequence ID" value="KPL76118"/>
        <property type="gene ID" value="ADN00_12320"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="1">
        <location>
            <begin position="2"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="368" mass="42247" checksum="BB5A135E541A053E" modified="2016-01-20" version="1">MCRLAALKSTQPLSPVLALRMMQAMQKGHDNSGFAMVMQDLEGAFADFKKYPLLSMACTSQGLEAAEEILETLGFTLKFDWQPDTVSAAGLDFRKMPHYVFRNYRYPEAFQQKPFSEQKALLVQTRLHLRQALAAIDGGFVYSFWPDVLTLKEIGNPSDIGTYFDLWKEESRLTARVISAQCRQNTNYKIVRYAAHPFFLEGYTLMANGENTNYQRNKEFQQNLHPGYLGFESDSQCFLYTLHYIREKLAWPLKYYKHVITPLPFEEMRARPDADILLRVRQACSHLEINGPNTIIFVLPAGEMGLVTDAKKLRPVVIGRHEEKVITASEVCGVDMVIPQRDPASDIYPSEREMLLINNQLEIEQWIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7C4</accession>
    <name>A0A0P6X7C4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">TrwB_AAD_bind domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_03355</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061549.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03355"/>
    <dbReference type="EnsemblBacteria" id="KPL78948">
        <property type="protein sequence ID" value="KPL78948"/>
        <property type="gene ID" value="ADN00_03355"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019476">
        <property type="entry name" value="T4SS_TraD_DNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10412">
        <property type="entry name" value="TrwB_AAD_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TrwB_AAD_bind" evidence="2">
        <location>
            <begin position="32"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="694"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="751"/>
            <end position="785"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="839" mass="93180" checksum="74289C7F7AC59437" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7G5</accession>
    <name>A0A0P6X7G5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Selenocysteine-specific elongation factor</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">SelB translation factor</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_03580</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Translation factor necessary for the incorporation of selenocysteine into proteins. It probably replaces EF-Tu for the insertion of selenocysteine directed by the UGA codon. SelB binds GTP and GDP.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03580"/>
    <dbReference type="EnsemblBacteria" id="KPL78984">
        <property type="protein sequence ID" value="KPL78984"/>
        <property type="gene ID" value="ADN00_03580"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.68"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001514">
        <property type="term" value="P:selenocysteine incorporation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015190">
        <property type="entry name" value="Elong_fac_SelB-wing-hlx_typ-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015191">
        <property type="entry name" value="Elong_fac_SelB-wing-hlx_typ-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004535">
        <property type="entry name" value="Transl_elong_SelB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09106">
        <property type="entry name" value="SelB-wing_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09107">
        <property type="entry name" value="SelB-wing_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="SSF50465"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00475">
        <property type="entry name" value="selB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="6">
        <location>
            <begin position="1"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00015953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00031615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL78984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="633" mass="69044" checksum="DC70881B45BE4753" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7T8</accession>
    <name>A0A0P6X7T8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Chaperone protein DnaJ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">dnaJ</name>
        <name evidence="10" type="ORF">ADN00_17630</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins and by disaggregating proteins, also in an autonomous, DnaK-independent fashion. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent interactions between DnaJ, DnaK and GrpE are required for fully efficient folding. Also involved, together with DnaK and GrpE, in the DNA replication of plasmids through activation of initiation proteins.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="6">Binds 2 Zn(2+) ions per monomer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="6">The J domain is necessary and sufficient to stimulate DnaK ATPase activity. Zinc center 1 plays an important role in the autonomous, DnaK-independent chaperone activity of DnaJ. Zinc center 2 is essential for interaction with DnaK and for DnaJ activity.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the DnaJ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000042">
        <property type="protein sequence ID" value="KPL71220.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064369.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000042.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17630"/>
    <dbReference type="EnsemblBacteria" id="KPL71220">
        <property type="protein sequence ID" value="KPL71220"/>
        <property type="gene ID" value="ADN00_17630"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2790"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031072">
        <property type="term" value="F:heat shock protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009408">
        <property type="term" value="P:response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd10719">
        <property type="entry name" value="DnaJ_zf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01152">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012724">
        <property type="entry name" value="DnaJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001305">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036410">
        <property type="entry name" value="HSP_DnaJ_Cys-rich_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00684">
        <property type="entry name" value="DnaJ_CXXCXGXG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="SSF46565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="SSF49493"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57938">
        <property type="entry name" value="SSF57938"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02349">
        <property type="entry name" value="DnaJ_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51188">
        <property type="entry name" value="ZF_CR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 6" id="KW-0235">DNA replication</keyword>
    <keyword evidence="2 6 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0346">Stress response</keyword>
    <keyword evidence="5 6 7" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 6 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="J" evidence="8">
        <location>
            <begin position="5"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="CR-type" evidence="9">
        <location>
            <begin position="133"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="repeat" description="CXXCXGXG motif" evidence="6">
        <location>
            <begin position="146"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="repeat" description="CXXCXGXG motif" evidence="6">
        <location>
            <begin position="163"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="repeat" description="CXXCXGXG motif" evidence="6">
        <location>
            <begin position="189"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="repeat" description="CXXCXGXG motif" evidence="6">
        <location>
            <begin position="203"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="CR-type" evidence="7">
        <location>
            <begin position="133"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL71220.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="376" mass="40331" checksum="1F4E6D06A3975E5C" modified="2016-01-20" version="1">MAPRDYYEILGVPRTATADELKSAFRQLARKYHPDVNKDPGAEDKFKEINEAYAVLSDADKRAAYDRYGYEGLNGMGGMPDFSTMDFSDLFEGLFGFGGFGGGGGSRRSRNAPRRGADLNMTVTLEFDEAVFGVEKEIEIVRDEVCATCSGSGAEPGTSPKTCSSCGGRGEVRQVRQTLLGSMVQVSTCPTCQGKGEVIDTPCHTCRGRGLERKTVKKVVPIPAGVDTGTQIRLAGEGQPGANGGPNGNIYLEIRVKTHKFFKRRKDDVLLDLNINVAQATLGAEVEIPTLKGTEKIKIPAGTQPGKVFTLKGKGIPHLRGSGNGDQLVVVNVAVPTHLSSEQRELFETLAKTLGTDVSPQEKSFVDVLKEVLGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7Z7</accession>
    <name>A0A0P6X7Z7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_12955</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12955"/>
    <dbReference type="EnsemblBacteria" id="KPL75545">
        <property type="protein sequence ID" value="KPL75545"/>
        <property type="gene ID" value="ADN00_12955"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1287"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022385">
        <property type="entry name" value="Rhs_assc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031325">
        <property type="entry name" value="RHS_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006530">
        <property type="entry name" value="YD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05593">
        <property type="entry name" value="RHS_repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03696">
        <property type="entry name" value="Rhs_assc_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01643">
        <property type="entry name" value="YD_repeat_2x"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132891" evidence="2">
        <location>
            <begin position="34"/>
            <end position="2360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1898"/>
            <end position="1963"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1907"/>
            <end position="1921"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1948"/>
            <end position="1963"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL75545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="2360" mass="263710" checksum="5098ED5742DE27C6" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X855</accession>
    <name>A0A0P6X855_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Pribosyltran domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_04895</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061833.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04895"/>
    <dbReference type="EnsemblBacteria" id="KPL79185">
        <property type="protein sequence ID" value="KPL79185"/>
        <property type="gene ID" value="ADN00_04895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pribosyltran" evidence="1">
        <location>
            <begin position="11"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="172" mass="19469" checksum="8BEB536987A92389" modified="2016-01-20" version="1">MRREALGWEDVDKLIDHLIPQFEIEFEAMVMITRGGIIPGGLLAEALNLTTLFTAAVDFPAEMELEKKSESARLLAWPKFIQFPESDLLRGRKTLVVDDVWGSGRTITAVKNRIAAMGSLPYTCVLHFNPYRNLFGTARPDYYAAVTDAHIIYPWEIKRGFEGAFLKGYVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X872</accession>
    <name>A0A0P6X872_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_07260</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062315.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78259">
        <property type="protein sequence ID" value="KPL78259"/>
        <property type="gene ID" value="ADN00_07260"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3272"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012985">
        <property type="entry name" value="Peptidase_S64_Ssy5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08192">
        <property type="entry name" value="Peptidase_S64"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="SSF50494"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="334" mass="36020" checksum="FA88BAA7C55777E5" modified="2016-01-20" version="1">MEQAEILQIQETYKESLLSFPQVVGVGTGYKVTRGQLTDRLCIVALVKTKLPKSSLLPQQIIPREIDGAATDVLEVGEIRAFQNRTDMWRPAPGGVSIGHFRITAGTLGCVVRDRQTGTRLILSNNHVLANSNSAELGDPILQPGPADGGTVKDHTIAELARFIPIQFNESDSTCSFANAVTDILNGLAGLFGSHHRLTARKYDTEARNLVDAALARPLNDADILDTILEIGEIDGTLVPELGMPVRKSGRTTGFTTGQITVVNATVSVNYMENRIARFEEQIVTTPFSQGGDSGSLVVHGDQPKAVGLLFAGSNQTTIFNPIQHVLDLLEIDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X972</accession>
    <name>A0A0P6X972_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_17825</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000043">
        <property type="protein sequence ID" value="KPL70894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064395.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000043.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17825"/>
    <dbReference type="EnsemblBacteria" id="KPL70894">
        <property type="protein sequence ID" value="KPL70894"/>
        <property type="gene ID" value="ADN00_17825"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2148"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022029">
        <property type="entry name" value="PG-bd_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007391">
        <property type="entry name" value="Vancomycin_resist_VanW"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12229">
        <property type="entry name" value="PG_binding_4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04294">
        <property type="entry name" value="VanW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="17"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="domain" description="PG_binding_4" evidence="2">
        <location>
            <begin position="90"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="PG_binding_4" evidence="2">
        <location>
            <begin position="272"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL70894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="621" mass="68885" checksum="6A4E8B215E92D385" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X977</accession>
    <name>A0A0P6X977_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_05180</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78652">
        <property type="protein sequence ID" value="KPL78652"/>
        <property type="gene ID" value="ADN00_05180"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007016">
        <property type="entry name" value="O-antigen_ligase-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04932">
        <property type="entry name" value="Wzy_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="54"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="100"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="125"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="147"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="184"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="266"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="299"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="325"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="355"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL78652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="679" mass="75386" checksum="1427131156AF7A84" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9Z0</accession>
    <name>A0A0P6X9Z0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_16765</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064202.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL71360">
        <property type="protein sequence ID" value="KPL71360"/>
        <property type="gene ID" value="ADN00_16765"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025906">
        <property type="entry name" value="YjfB_motility"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14070">
        <property type="entry name" value="YjfB_motility"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL71360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="71" mass="7411" checksum="59F988300C30350C" modified="2016-01-20" version="1">MSVNSVSMVDLATSLAAQATTMKAGEVSTAIGTHVLKKVMDQNELQAQALIKMIQQAPSLDGTGKHVDLSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XA29</accession>
    <name>A0A0P6XA29_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ADN00_17240</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064293.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL71433">
        <property type="protein sequence ID" value="KPL71433"/>
        <property type="gene ID" value="ADN00_17240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902531">
        <property type="term" value="P:regulation of intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 5" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="7">
        <location>
            <begin position="6"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="8">
        <location>
            <begin position="137"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="9">
        <location>
            <begin position="207"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="8">
        <location>
            <begin position="262"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="9">
        <location>
            <begin position="340"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="8">
        <location>
            <begin position="571"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="9">
        <location>
            <begin position="645"/>
            <end position="697"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="6">
        <location>
            <begin position="717"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="5">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL71433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="934" mass="106164" checksum="59DB85DB9DA27466" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XA42</accession>
    <name>A0A0P6XA42_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_16175</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064080.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72024">
        <property type="protein sequence ID" value="KPL72024"/>
        <property type="gene ID" value="ADN00_16175"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132950" evidence="2">
        <location>
            <begin position="28"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="255"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="313"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="258"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="320"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL72024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="479" mass="51724" checksum="8189BBF3B47A0A02" modified="2016-01-20" version="1">MRTGTSFWICIWLSILLSIATISTASAQTPEPPAPQKVIAIYDGNIPPTFSQNCNNIPIKITIEAWNVGAAGGSNYGEATITIEGPDCDIDSKGNSTPGQYGRTELKGIFSGGPDGKIPLKDPENPKLVVTALFVDGKTVRLSAIGDGTIYIDIPVINPEVFESMGPLPTMAPTPGSFCIPVISNINNLKPGEILSPSLSFVDENNNPVAALSNVWYINGVQTNSVTWDGKETTLILQYTCPDTSAHEKRITIPAYQKDNEVSPNQDANQQTETTNPTRTPAIAAGVVAAAAGAAGAVAAGGYAATRMQPVKPAKITPPSKQTAPKNQNTASSTEISSQKAPQPSRPRLTDEERGNLQTIRTMMQNQLSEYRTDYNNLTHDRQVLVRLFKNNALKFVSKKAVIGGTIVTTNPVGFMAQTLLDPVLNRAFSMHDTSQDSKIILHIHSLINLSGERMTEIRREIIHLKNEIDLINQRLADN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAS0</accession>
    <name>A0A0P6XAS0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ParB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_15765</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063990.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72271">
        <property type="protein sequence ID" value="KPL72271"/>
        <property type="gene ID" value="ADN00_15765"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003115">
        <property type="entry name" value="ParB/Sulfiredoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036086">
        <property type="entry name" value="ParB/Sulfiredoxin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02195">
        <property type="entry name" value="ParBc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00470">
        <property type="entry name" value="ParB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110849">
        <property type="entry name" value="SSF110849"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ParB" evidence="1">
        <location>
            <begin position="27"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="255" mass="28996" checksum="CD797EED7D55EF23" modified="2016-01-20" version="1">MADETRINDLLTQLNAEIGEYTPYKLAFVSPGEIQPVEKNAHFMPKRLFDQLVDNIKNDQNLSTLPFCWKKADGSFVVLSGNHRVQAAKEANIQKILVLYTDEDLTRSRQIAIQLSHNSLVGQDNPTLLLDLWNELDSLQAKIYTGLDDNLLQTLPPVNVIRLNEEPLRLEEPSILFVPAEIERVSDVIKRIGKSNRTRLIAGVDEFDRFFDKLLEFKEAEGIINTATAFAKMADILEEYLAQNEHHEVEHGQTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAY1</accession>
    <name>A0A0P6XAY1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ApbA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09985</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062856.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09985"/>
    <dbReference type="EnsemblBacteria" id="KPL76917">
        <property type="protein sequence ID" value="KPL76917"/>
        <property type="gene ID" value="ADN00_09985"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013332">
        <property type="entry name" value="KPR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02558">
        <property type="entry name" value="ApbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ApbA" evidence="1">
        <location>
            <begin position="3"/>
            <end position="156"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="317" mass="35184" checksum="A9F3C7453868EBBE" modified="2016-01-20" version="1">MNILVIGTGVIGTIYGMALSNAGHQVTHYVRPGKGQQFTNGIRVHILDGRGKKPHEYETHYDLKVTETLASQPDYDLILVSVRHYQLPALLPLLREHAGQADILFFNGNWQGLDEIDACLPRSRYLWGFPVAGGGYTPDSTLNAALLDEIRLGEIDGQETPRLQRIKAAFESAELKVDVQANILHWLWVHFAINSGVIGAAFKAGGARALLNSIPRLREAILAGREALEVCKRRGVKIADFEDARSFSQPAWLGAVAIWAMMKTNLPARRIMETHTAVDELQAIFSDVRTTGEQLQVSMPYFQSLRAYVESPRLVSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBE0</accession>
    <name>A0A0P6XBE0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_16130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064071.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72019">
        <property type="protein sequence ID" value="KPL72019"/>
        <property type="gene ID" value="ADN00_16130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="176" mass="20400" checksum="B7CEC90F28B7A5B8" modified="2016-01-20" version="1">MPIDSITDCQLDSLPRMSEGQVKGDPLSLKNWIKRSLAKPWNYVVKKRLKRMSAALFGDTGVPTSVGKQAPALAVSLAAGDWVRVRSREEIEATLDRWHELRGCAFLENMWQYCGTTQRVLTSMQRFLDERDYKVKKCRGIVLLENIHCEGTPVFGRCDRRCYLFWREEWLDKISE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBK1</accession>
    <name>A0A0P6XBK1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Yip1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_08700</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000022">
        <property type="protein sequence ID" value="KPL77663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062605.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000022.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08700"/>
    <dbReference type="EnsemblBacteria" id="KPL77663">
        <property type="protein sequence ID" value="KPL77663"/>
        <property type="gene ID" value="ADN00_08700"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006977">
        <property type="entry name" value="Yip1_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04893">
        <property type="entry name" value="Yip1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="59"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="102"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="145"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="domain" description="Yip1" evidence="6">
        <location>
            <begin position="30"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL77663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="179" mass="19302" checksum="6C40B58AA93C55CD" modified="2016-01-20" version="1">MFERIVRAIRLDKSLYREVADLPALTSEGALVAVGVALISSLGMLGAGPRALFAYLAQVANSLLFGWILWSLVAYFVGTQFFKGRSNVEEMLRVLGYANAPRLLGVLGFIPCVGWLFSVTGWVLSVIAGVIAIREAMEFETSDAIVTALVSFVLYIIASITIGLVFAGLSLPFHLLTSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XD35</accession>
    <name>A0A0P6XD35_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NciI</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_08735</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000022">
        <property type="protein sequence ID" value="KPL77667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062612.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000022.1"/>
    </dbReference>
    <dbReference type="REBASE" id="132869">
        <property type="entry name" value="OapP3M1ORF8740P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77667">
        <property type="protein sequence ID" value="KPL77667"/>
        <property type="gene ID" value="ADN00_08735"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1464"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.210.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029127">
        <property type="entry name" value="MvaI_BcnI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043004">
        <property type="entry name" value="MvaI_BcnI_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043005">
        <property type="entry name" value="MvaI_BcnI_rec"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15515">
        <property type="entry name" value="MvaI_BcnI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MvaI_BcnI" evidence="1">
        <location>
            <begin position="10"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF15515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="261" mass="29946" checksum="58AA5C55CB7CB01A" modified="2016-01-20" version="1">MKTYTKESLIAALKEIKNRRWIPNARPGNSGGIGNTLEDLLGIQENNLPIPNAAEWELKCQRANTSALTTLFHMEPSPRALKFVPNILLPNYGWKHELAGTKYPVNEMSFRQTIHGLDRSDRGFMVEIDKTSRKVLISFDASKVDPRHTEWLAWVDSRAGLDELTPQPYWGFDDLYHKAGTKLLNTFYVQAEVMKNGDEEFFYYNRILILRGFSVENFVKAIVEGNVLVDFDARTGHNHGTKFRLRQNALPMLYSEIQEVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDF3</accession>
    <name>A0A0P6XDF3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_07360</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07360"/>
    <dbReference type="EnsemblBacteria" id="KPL78276">
        <property type="protein sequence ID" value="KPL78276"/>
        <property type="gene ID" value="ADN00_07360"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3294"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005311">
        <property type="entry name" value="PBP_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036138">
        <property type="entry name" value="PBP_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03717">
        <property type="entry name" value="PBP_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56519">
        <property type="entry name" value="SSF56519"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PBP_dimer" evidence="3">
        <location>
            <begin position="38"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="2">
        <location>
            <begin position="253"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL78276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="582" mass="64859" checksum="E78BE09234592C70" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDM4</accession>
    <name>A0A0P6XDM4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_08120</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062486.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08120"/>
    <dbReference type="EnsemblBacteria" id="KPL77840">
        <property type="protein sequence ID" value="KPL77840"/>
        <property type="gene ID" value="ADN00_08120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000841">
        <property type="entry name" value="Pept_M23A_Blytic"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00933">
        <property type="entry name" value="BLYTICPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="SSF54106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LysM" evidence="2">
        <location>
            <begin position="92"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="527" mass="56668" checksum="5BF20C0B415DED6B" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XEF3</accession>
    <name>A0A0P6XEF3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CcmF_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_06610</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000017">
        <property type="protein sequence ID" value="KPL78587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062189.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000017.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06610"/>
    <dbReference type="EnsemblBacteria" id="KPL78587">
        <property type="protein sequence ID" value="KPL78587"/>
        <property type="gene ID" value="ADN00_06610"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015232">
        <property type="term" value="F:heme transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032523">
        <property type="entry name" value="CcmF_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003567">
        <property type="entry name" value="Cyt_c_biogenesis"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43653">
        <property type="entry name" value="PTHR43653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16327">
        <property type="entry name" value="CcmF_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0201">Cytochrome c-type biogenesis</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="125"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="226"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="266"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="295"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="326"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="365"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="409"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="440"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="463"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="516"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="639"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="domain" description="CcmF_C" evidence="3">
        <location>
            <begin position="346"/>
            <end position="658"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022748"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL78587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="689" mass="75382" checksum="E0FB8B1ECBC3CCD9" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XFH0</accession>
    <name>A0A0P6XFH0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Metallophos domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_14630</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000035">
        <property type="protein sequence ID" value="KPL73573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063773.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000035.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14630"/>
    <dbReference type="EnsemblBacteria" id="KPL73573">
        <property type="protein sequence ID" value="KPL73573"/>
        <property type="gene ID" value="ADN00_14630"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="1">
        <location>
            <begin position="1"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL73573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="222" mass="25454" checksum="80E459BDB60BC847" modified="2016-01-20" version="1">MKILSVSDVELGLIYSQQITQRFADVDVVISCGDLPYYYLEYIVSTLNVPLYYVRGNHASKVEICVGGERQSPWGGYDLHRRVRRDRSGLLLAGIEGSLRYNNGPYQYSQGEMWRYVLGLTPSLFLNKLRFGRYLDIFVTHAPSWKILDRDDLAHQGIKAFRWLIETFQPALHLHGHVHIYRRNTVTEAAVQKCQVINTYGFREISIDLDDLSAGSPSAIRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XFN4</accession>
    <name>A0A0P6XFN4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Amidohydro-rel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_03605</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="PTM">
        <text evidence="7">Carbamylation allows a single lysine to coordinate two divalent metal cations.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallo-dependent hydrolases superfamily. Hydantoinase/dihydropyrimidinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061599.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03605"/>
    <dbReference type="EnsemblBacteria" id="KPL78989">
        <property type="protein sequence ID" value="KPL78989"/>
        <property type="gene ID" value="ADN00_03605"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016812">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01314">
        <property type="entry name" value="D-HYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002195">
        <property type="entry name" value="Dihydroorotase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011778">
        <property type="entry name" value="Hydantoinase/dihydroPyrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02033">
        <property type="entry name" value="D-hydantoinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00482">
        <property type="entry name" value="DIHYDROOROTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="8">
        <location>
            <begin position="50"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-carboxylysine" evidence="7">
        <location>
            <position position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR611778-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL78989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="473" mass="51985" checksum="CEBFD6D93AA9CE3B" modified="2016-01-20" version="1">MTTIIKNGTLITAADTFEADILIEGEKISLVGKNLQPPAGAEVIDASGKLVMPGGVDPHVHLNLPMFGTVSSDDHYTGHKAAAFGGTTTALDFIPHGPGSFRENIDGWHARADDLAAIDFGFHMNVERVNDDVRKEFHVLGEEGISSIKVFSAYNNRMRLQDGDIFRVLRMAGERGYLTMMHAENGDVIEQLVAEALANGNISTEWHAHTRPAWGAVEAALRGFAMAEQAGAPLYLVHMNTGGETDMLQYARERGLPVMGETCPQYMFFTLEDLQRPDGAKWICSPPMRSKADNERIWKGVMEGTIQTIGTDHCPFFYDGTKPILYEGKEVAIPGKELGKNNFTEIPNGLPGIGDRLPILWTYGVGSGKITANQFVALCSTNPAKIFGMYPRKGSLMPGADADIAIWDPEKTLEYGVKVAHHRTDYNLFEGWKLKGYPEKVFLRGKLIVDGQKWMGKAGMGRYLHRDASAEVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XG55</accession>
    <name>A0A0P6XG55_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_04695</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061799.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79153">
        <property type="protein sequence ID" value="KPL79153"/>
        <property type="gene ID" value="ADN00_04695"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.301"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133039" evidence="2">
        <location>
            <begin position="23"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="245" mass="26803" checksum="ADD697252A0A6032" modified="2016-01-20" version="1">MKKYTILLAGALLLGLLLAACAAPAPAVEPTVAPPAELPTATLAPTSTPTTIPPTATPLPTDTPEPTPTPQLALEADGFSAWCLPQDSLDDPASFAMPEYAQVAQIVDGLPELITEVKSCTFLFQFNQPAPAGLVLEMYDTRETPFLSFELQTNPDEPRQALAYSVNPYVIDPPFWTIDYNFVLRSAGGDTLWESPVRFRRGWTPKLCWGGVWPDPATLDCPWLGEAHPWDAWYGFEEPYPDGIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGF7</accession>
    <name>A0A0P6XGF7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aamy domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_06130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78800.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062084.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78800">
        <property type="protein sequence ID" value="KPL78800"/>
        <property type="gene ID" value="ADN00_06130"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1705"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006047">
        <property type="entry name" value="Glyco_hydro_13_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045857">
        <property type="entry name" value="O16G_dom_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00128">
        <property type="entry name" value="Alpha-amylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00642">
        <property type="entry name" value="Aamy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aamy" evidence="1">
        <location>
            <begin position="17"/>
            <end position="372"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78800.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="459" mass="53270" checksum="89EAF41D85F47D71" modified="2016-01-20" version="1">MTIINKPQWLNNAVFYQIFPDRFANGDLSNDPQGVFPWGSQPDREHFWGGDLRGIIQNLDYLQELGINALYLNPIFKAGTNHRYDTFDYYEIDPVLGTKSDFKQLVEESHHRGIRIILDGVFNHCGLGFSPFLDLVEKGDASPYRDWFFVDRFPVTTSPLSYQTCGGAEYLPKLNTANQVVQDFFLDVAEYWIREFNIDGWRLDVPWKADFDFWKRFRTRVKQVRPDAYIVGEIWRDSLTWLDGTTCDGTMNYPLREYLLDYCVHDHMDAEDFTYFLTRLLDDLGENRGGQLNLIGSHDTARVLELAAGDRRKIKLISGLQMLLPGVPMVYYGDEVGLRGANDPDCRRCMPWEPETWDQELYAHYKKMIQIRRQHTWLSHAEVKVEKVLNGYLALWLQSGAERMLVIANSRGAVRDQTIVLDGVVANSLVELISEKHYNIDGNLKLDWIEERSLLVFKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XHA9</accession>
    <name>A0A0P6XHA9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_04890</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061832.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04890"/>
    <dbReference type="EnsemblBacteria" id="KPL79184">
        <property type="protein sequence ID" value="KPL79184"/>
        <property type="gene ID" value="ADN00_04890"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.345"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007607">
        <property type="entry name" value="BacA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04519">
        <property type="entry name" value="Bactofilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133062" evidence="2">
        <location>
            <begin position="33"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="307"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="345"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="380"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="423"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="447"/>
            <end position="467"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="490" mass="51547" checksum="509405D6224AE0DA" modified="2016-01-20" version="1">MSTFWKSTGLRISLALMLVAVLFAGIAAPVQAADIDNDGYVGPNEVIDDDLIISGEKVVIEGTVNGLLIATGATVTIKGQINGDAILLGSTVEVTEEAVITGNVFSGASQVKVNGQVGGSVAMGSQVIYMEGAQVGRNVYFGTYSFQDDARTSIARGVYGGAYQIILNGTVDRDVNLSAAALELGGKVNGNAVLDVEAPGSGEEMPFSPFMFMPQQYGVVIPPTMKPGLRISDSAEIGGQLVYTSPVEQAEAIETALQGGVVYQTPVPAETSADGKTALKPAEPERGTFGFFASRVLKWFWKLLRDLITLLLLGGLCVWLIPALYQKTVEAVKAKPGPAAGTGALVYLGGHVGAFVVFFLILIAGLLFSVLTLTGISSTIFGMGFSALALAFAAFRLLVVYGSKLVIAYLAGEWVLSKIAPQARNKAVWSMVIGVVIYIILRSIPIFGWLFGLVVTIFGLGGMWLVFQNWRNPAAAPAVEPAPVVETPAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XHT2</accession>
    <name>A0A0P6XHT2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DUF4332 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_02835</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000013">
        <property type="protein sequence ID" value="KPL79385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061445.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000013.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79385">
        <property type="protein sequence ID" value="KPL79385"/>
        <property type="gene ID" value="ADN00_02835"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025567">
        <property type="entry name" value="DUF4332"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14229">
        <property type="entry name" value="DUF4332"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4332" evidence="3">
        <location>
            <begin position="101"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL79385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="226" mass="24603" checksum="1AA0702DA59BB887" modified="2016-01-20" version="1">MSPLYGMDLTQFSLARLKAVFTSGDLLPSRKLLSEAVEERFAILEQMGLHHVQDVIDALSTPKKIKAFSQASGLSEDYLTLLRRQANSYIPNPIALKDIPGVDPAHTQALAALGLRDTRQLFARVCSRAGRAALQAESGLPAEALLELTRLADVSRAGWVGPVFARLLLEAGADSIESLVASQPAELFEHLMAANQRLQLTKALFTPKDVAACITYARELPDRVEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XJ97</accession>
    <name>A0A0P6XJ97_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01835</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000007">
        <property type="protein sequence ID" value="KPL80035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061258.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000007.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80035">
        <property type="protein sequence ID" value="KPL80035"/>
        <property type="gene ID" value="ADN00_01835"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="83"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="116"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="150" mass="17464" checksum="CE7E1F9B45D2E283" modified="2016-01-20" version="1">MRKSPFNLDERERDVYKNLIVILYFITLIVLIILQLYRQFVLRQPSEQWDDIALLITFNVLLLIGGGIFLSGHVNLKRIKMRYLVMGYAAFVLVGLLFTIFKYTVLLGQAITLQHIWNYLIIILPITAILVLGWGLLGYLGHQRMENNLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XJU5</accession>
    <name>A0A0P6XJU5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_12230</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the ABC-3 integral membrane protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063299.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12230"/>
    <dbReference type="EnsemblBacteria" id="KPL76102">
        <property type="protein sequence ID" value="KPL76102"/>
        <property type="gene ID" value="ADN00_12230"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3922"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037294">
        <property type="entry name" value="ABC_BtuC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001626">
        <property type="entry name" value="ABC_TroCD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30477">
        <property type="entry name" value="PTHR30477"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00950">
        <property type="entry name" value="ABC-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81345">
        <property type="entry name" value="SSF81345"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="17"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="66"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="136"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="175"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="198"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="223"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="248"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL76102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="282" mass="30302" checksum="694449D98D81C463" modified="2016-01-20" version="1">MIESILDALQFTFMRNALAASLLVSIACGIIGTYVVVNRIVFISGGIAHAAYGGIGLGYFFKFNPILGAIAFSLLAALGMGAVQRKTRERADTIIGVMWAIGMAVGIILIDRSAGYKTDLMSYLFGSILSVPAADLVLMAILDGLIILAVIFFYKELQAISFDETFASLQNVPVNLIYLLLLALIAVTVVMMMRVVGLIMVIAMLTIPAAISGMFVRNLKSMMALSALLGIVFSITGLWISYTWNLTSGATIILVSGFAYLLSLLIQSLRPTQVTFSTKDSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XLD0</accession>
    <name>A0A0P6XLD0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063000.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10760"/>
    <dbReference type="EnsemblBacteria" id="KPL77035">
        <property type="protein sequence ID" value="KPL77035"/>
        <property type="gene ID" value="ADN00_10760"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="231"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="271"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="306"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="343"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="382"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="405"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="439" mass="47704" checksum="765D7DC2194736D5" modified="2016-01-20" version="1">MTLQPRPLTLRRIIKTWWPLAASWLMMTLAFPAMNAVIARLADPEINLAAYGSVVHPISLIIESPIIMLLAASTALSKDWASYLKVRRFTHIAAVSLGLLHALVAFTPLYYFVTRQLLGVPEEIIEPARLGLMFMTPWTPAIALRRFEQGAMIRYGHSDAVVVGTVIRLVTYLLALGVGYSLQTVPGAVVGAAAQALSVTAEGTYAVLRVRPVLDEIRAAPAVEPLTWGKFFAFYVPLALTSLMSFLWQPVASAGLSRMPRALESLAVWPVVYSLVTVLRSFGTAYNEVVVALMGEPRAHTSLRRFTTGLALSTSGLHLLLMITPLAYLYFNQLSALSQPLSSVAVQGTWILLPIPALVAMQSWYQGAIMHGSDTRGISESVAIFLATAALVLAVGVALGRGIGLYYGALAYLLASLAQTAWQWLRSRPAMRAARSESR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XMC5</accession>
    <name>A0A0P6XMC5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">ATP-dependent 6-phosphofructokinase</fullName>
            <shortName evidence="15">ATP-PFK</shortName>
            <shortName evidence="15">Phosphofructokinase</shortName>
            <ecNumber evidence="15">2.7.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="15">Phosphohexokinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="primary">pfkA</name>
        <name evidence="17" type="ORF">ADN00_14800</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 15">Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 15">
            <text>ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6-bisphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16109"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 15">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="15">Allosterically activated by ADP and other diphosphonucleosides, and allosterically inhibited by phosphoenolpyruvate.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5 15">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 15">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Prokaryotic clade 'B1' sub-subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.11" evidence="15"/>
    <dbReference type="EMBL" id="LGCL01000036">
        <property type="protein sequence ID" value="KPL73062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063809.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000036.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14800"/>
    <dbReference type="EnsemblBacteria" id="KPL73062">
        <property type="protein sequence ID" value="KPL73062"/>
        <property type="gene ID" value="ADN00_14800"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1823"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00182"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003872">
        <property type="term" value="F:6-phosphofructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00339">
        <property type="entry name" value="Phosphofructokinase_I_B1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022953">
        <property type="entry name" value="ATP_PFK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012003">
        <property type="entry name" value="ATP_PFK_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012828">
        <property type="entry name" value="PFKA_ATP_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015912">
        <property type="entry name" value="Phosphofructokinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000023">
        <property type="entry name" value="Phosphofructokinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035966">
        <property type="entry name" value="PKF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00365">
        <property type="entry name" value="PFK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000532">
        <property type="entry name" value="ATP_PFK_prok"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00476">
        <property type="entry name" value="PHFRCTKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53784">
        <property type="entry name" value="SSF53784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02482">
        <property type="entry name" value="PFKA_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00433">
        <property type="entry name" value="PHOSPHOFRUCTOKINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 15" id="KW-0021">Allosteric enzyme</keyword>
    <keyword evidence="12 15" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 15" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="14 15" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="11 15 17" id="KW-0418">Kinase</keyword>
    <keyword evidence="13 15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 15" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 15" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PFK" evidence="16">
        <location>
            <begin position="3"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="ADP binding; allosteric activator; shared with dimeric partner" evidence="15">
        <location>
            <begin position="21"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="15">
        <location>
            <begin position="125"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="15">
        <location>
            <begin position="169"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="ADP binding; allosteric activator" evidence="15">
        <location>
            <begin position="185"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="region of interest" description="ADP binding; allosteric activator" evidence="15">
        <location>
            <begin position="213"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="15">
        <location>
            <begin position="253"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="15">
        <location>
            <position position="127"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="11"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <begin position="72"/>
            <end position="73"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <begin position="102"/>
            <end position="105"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="154"/>
        </location>
        <ligand>
            <name>ADP</name>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <note>allosteric activator</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="162"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="222"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="247"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00002659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KPL73062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="323" mass="34489" checksum="EDBC3B5FEFDDD9FD" modified="2016-01-20" version="1">MKRVAVLTSGGDAPGMNAAIRAVVRAGIAKGWEMYGVRLGYKGLIEGRISQLGVRDVGGIMQRGGTVLGSARCLEFKTKEGQIQAIRSMNQLGIEALVVIGGNGSQTGANALRLNDFPVVGVASTIDNDLFGSDITIGVDTALNIALEAIDRLKTTASSHQRAFLLEVMGRDCGYLALMSAIAGGAEMVVIPEVETEPEEVVQAIWRAYEAGKAHAIIVVAEGAKYNANRLAAYCEEHQERLGFLLRATQLGHVQRGGNPGAFDRILATRLGAAAIDQIEKGEYGVLMGWIKNEATATPLEEVVAKKKPLDMKLYELAKVLDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XNH5</accession>
    <name>A0A0P6XNH5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_07885</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000020">
        <property type="protein sequence ID" value="KPL78086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062443.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000020.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78086">
        <property type="protein sequence ID" value="KPL78086"/>
        <property type="gene ID" value="ADN00_07885"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="154" mass="17694" checksum="0C3B5DE39A8CC872" modified="2016-01-20" version="1">MKLPSQIDIQVVCNDEQNLGDIIVRMIVRSGSKNPFQVYFPKTNKEGRTSITASEFRDQFDSHYEIGLMDYNGSIETASQVAAFDLQYQDKLYPSLEIARKRPLLGYERLKWQTSGEMIAYFLSCRNSEFFTEPQSVEIHLNEVIQLVISKNAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XP08</accession>
    <name>A0A0P6XP08_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_07790</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062415.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78342">
        <property type="protein sequence ID" value="KPL78342"/>
        <property type="gene ID" value="ADN00_07790"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011737">
        <property type="entry name" value="CHP02206_TP0381"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09529">
        <property type="entry name" value="Intg_mem_TP0381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02206">
        <property type="entry name" value="intg_mem_TP0381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="212"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="250" mass="27470" checksum="2C964C28E196682B" modified="2016-01-20" version="1">MGEFFAKDYHGAPFELFGPAHLIALGLVALVIVALCVIGRRLDAAGRMRIRRGFAVTLVVVEVSWHVWNAATGQWTVQTMLPLHLCSALVWLSAVMMLTGNYRIYEFAYLLGIAGASQALLTPDAGVYGFPHFRFFQVILSHGSIVGGAIFMTVVEGYRPTPRSLLRVLLFGNLYMAFVGLVNWLVGSNYLFIAHKPDTASLLDVLPAWPWYILWIEAIGAVAVLLLYSPFAVKDWKARATAQKTPSAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XP28</accession>
    <name>A0A0P6XP28_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AlaDh_PNT_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10605</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062971.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10605"/>
    <dbReference type="EnsemblBacteria" id="KPL77011">
        <property type="protein sequence ID" value="KPL77011"/>
        <property type="gene ID" value="ADN00_10605"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007886">
        <property type="entry name" value="AlaDH/PNT_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05222">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01003">
        <property type="entry name" value="AlaDh_PNT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AlaDh_PNT_N" evidence="1">
        <location>
            <begin position="9"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="377" mass="42310" checksum="99FCE352D8E87FA8" modified="2016-01-20" version="1">MPSRSKKIGLPRMKAEAGEKRVFLPEFVNKLVGLGFEMFIEEGYGSRSGYTFDDYQQGSPMVHRVSRKDAFAQPCVLILRSPNPEEFDLIPAGTCLISMLHYPTRANRVQILRQKGIQAISLDSIVDDYNLRLVENMKAVAWNGLEAAFDVLETRFNGLVKPDGHPWKSLILGTGMVGKHAIDAATKLGNIERNNEHIENNGPGAIAWSVGRNISPKPEQMRELFSQVDVLVDASQRRDASQPVVPNEWLAWLPEHAVVVDLSVDPYKLDQDPPVVRGIEGIPQGDLNQYIFHPNDPRWCDKIPASIPTAQRRSTVTCYSWPGIHPEACMRHYAQQILPLMEVLAQKSCSDLSPYGSYFERALYRATLKAFLASQEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQ39</accession>
    <name>A0A0P6XQ39_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Histidinol dehydrogenase</fullName>
            <shortName evidence="4">HDH</shortName>
            <ecNumber evidence="4">1.1.1.23</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">hisD</name>
        <name evidence="11" type="ORF">ADN00_17430</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the sequential NAD-dependent oxidations of L-histidinol to L-histidinaldehyde and then to L-histidine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>H2O + L-histidinol + 2 NAD(+) = 3 H(+) + L-histidine + 2 NADH</text>
            <dbReference type="Rhea" id="RHEA:20641"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="ChEBI" id="CHEBI:57699"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.23"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4 9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="4 9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 9/9.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 5 10">Belongs to the histidinol dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.23" evidence="4"/>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71463.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064326.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17430"/>
    <dbReference type="EnsemblBacteria" id="KPL71463">
        <property type="protein sequence ID" value="KPL71463"/>
        <property type="gene ID" value="ADN00_17430"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.554"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00014"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004399">
        <property type="term" value="F:histidinol dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06572">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01024">
        <property type="entry name" value="HisD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001692">
        <property type="entry name" value="Histidinol_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022695">
        <property type="entry name" value="Histidinol_DH_monofunct"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012131">
        <property type="entry name" value="Hstdl_DH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21256">
        <property type="entry name" value="PTHR21256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00815">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000099">
        <property type="entry name" value="Histidinol_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00083">
        <property type="entry name" value="HOLDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00069">
        <property type="entry name" value="hisD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00611">
        <property type="entry name" value="HISOL_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="1 4 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 7" id="KW-0520">NAD</keyword>
    <keyword evidence="3 4 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 9" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton acceptor" evidence="4 6">
        <location>
            <position position="339"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4 6">
        <location>
            <position position="340"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 7">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 7">
        <location>
            <position position="203"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 7">
        <location>
            <position position="226"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 8">
        <location>
            <position position="249"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 8 9">
        <location>
            <position position="271"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 8 9">
        <location>
            <position position="274"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 8">
        <location>
            <position position="340"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 8 9">
        <location>
            <position position="373"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 8">
        <location>
            <position position="427"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4 8 9">
        <location>
            <position position="432"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR000099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000099-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000099-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000099-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000099-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL71463.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="440" mass="47188" checksum="6EC69040C94EA4A3" modified="2016-01-20" version="1">MFKQYSPQTAQETILKRVPMDEFDVPEKLLDSIAALFGERLTPDQAVARILREVRQEGDAALRRWTQKLDGQSPDSFRVPEEDVRAALQSLSDEELNALQLAADRIRRFHQAQPVTSWFTNALGGTLGQFMRPIRRVGLYIPGGTAPLPSSVLMSAVIAQVAGVKEIAIVAPPQKQTGTIHPSILAAAALIGITEVYAIGGAQAIAALAFGTESIPRVDKIYGPGNLFVALAKRQVFGTVGIDSVAGPTETVVIADESANPAWVAADLLAQAEHDVLASAILLTPSESLIKKVQEEVVKQYNVRDRNEILEASLQNRSGAVLVKDLQQAADLANQYAPEHLCLSVSDPWQLSQEIYAAGGIFMGENSFEVLGDYVAGPSHVMPTGGSARFNSPLNVLDFVHVVSLVALDPQTTRQIAPAAAIIAETEGLDAHANAAKVRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQC4</accession>
    <name>A0A0P6XQC4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_03395</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78955.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061557.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78955">
        <property type="protein sequence ID" value="KPL78955"/>
        <property type="gene ID" value="ADN00_03395"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010375">
        <property type="entry name" value="CdAMP_rec"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38456">
        <property type="entry name" value="PTHR38456"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06153">
        <property type="entry name" value="CdAMP_rec"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="SSF54913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78955.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="112" mass="12211" checksum="55B3111F3011E12A" modified="2016-01-20" version="1">MNDQNPNALLIAIVQSQDVDKALDNLEELGASVARLPSVGGFLGRRNATLFIAIPAADVQIVYETLRDTCRQRVEYISTPMESAPFPMPNLTPVTIGGVTVFALNIEHFEVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XR03</accession>
    <name>A0A0P6XR03_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Ribokinase</fullName>
            <shortName evidence="10">RK</shortName>
            <ecNumber evidence="3 10">2.7.1.15</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">rbsK</name>
        <name evidence="13" type="ORF">ADN00_15885</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP + D-ribose = ADP + D-ribose 5-phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13697"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:47013"/>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.15"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10">Requires a divalent cation, most likely magnesium in vivo, as an electrophilic catalyst to aid phosphoryl group transfer. It is the chelate of the metal and the nucleotide that is the actual substrate.</text>
    </comment>
    <comment type="activity regulation">
        <text evidence="10">Activated by a monovalent cation that binds near, but not in, the active site. The most likely occupant of the site in vivo is potassium. Ion binding induces a conformational change that may alter substrate affinity.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Carbohydrate metabolism; D-ribose degradation; D-ribose 5-phosphate from beta-D-ribopyranose: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the carbohydrate kinase PfkB family. Ribokinase subfamily.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the carbohydrate kinase pfkB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.15" evidence="3 10"/>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL71984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064024.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15885"/>
    <dbReference type="EnsemblBacteria" id="KPL71984">
        <property type="protein sequence ID" value="KPL71984"/>
        <property type="gene ID" value="ADN00_15885"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3610"/>
    <dbReference type="UniPathway" id="UPA00916">
        <property type="reaction ID" value="UER00889"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004747">
        <property type="term" value="F:ribokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019303">
        <property type="term" value="P:D-ribose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01174">
        <property type="entry name" value="ribokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01987">
        <property type="entry name" value="Ribokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011877">
        <property type="entry name" value="D_ribokin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002139">
        <property type="entry name" value="Ribo/fructo_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00990">
        <property type="entry name" value="RIBOKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02152">
        <property type="entry name" value="D_ribokin_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00584">
        <property type="entry name" value="PFKB_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="10" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 10 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9 10" id="KW-0630">Potassium</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="12">
        <location>
            <begin position="1"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="11"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="10">
        <location>
            <begin position="39"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="10">
        <location>
            <position position="247"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="215"/>
            <end position="220"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="243"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="246"/>
            <end position="247"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="247"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="277"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="280"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="282"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="286"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005380"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU003704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KPL71984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="302" mass="31559" checksum="36C3967043379C5F" modified="2016-01-20" version="1">MKKILVVGSLNMDLVVQAPRHPKVGETIFGSQFHTFPGGKGANQAVAAARIGAPVTMIGRVGADGFGQQLLEIAAQEGIDAQWIEAVSGQPTGLALITVSDDGQNTIVVISGANTCLTTSDLDAAESAFDEAAALVLQLEVPMPVNQRAVELAHQKNIPVLLNPAPAQQIPIEILRQVDILIPNQHELLLISNQPDMESAIQALLGLGVKQLVVTLGEDGALLVSARERQHIPAFKVTPVDTTAAGDSFVGALAVALTQGQPLPQAARFASAAAAISVTRPGAQPSLPIRSEVEKFLKEQNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XR37</accession>
    <name>A0A0P6XR37_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_16345</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064110.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16345"/>
    <dbReference type="EnsemblBacteria" id="KPL72048">
        <property type="protein sequence ID" value="KPL72048"/>
        <property type="gene ID" value="ADN00_16345"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3709"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="1152" mass="131343" checksum="ED312B70A06456C4" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XR47</accession>
    <name>A0A0P6XR47_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_16460</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064133.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72067">
        <property type="protein sequence ID" value="KPL72067"/>
        <property type="gene ID" value="ADN00_16460"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="141" mass="15768" checksum="502022D8E060038A" modified="2016-01-20" version="1">MNELIEVTYTSDAGSILPELQWHEEIIVNEDAVTFLRNGKTPDTKVNAGTWNVQTDEKTLQALFSALKNVDCANIKRIEPTDPPDGGGTETYILRFADETTCSLYFDPGTSYENGDFVVKPVQNFMQALAFPPEALNRYID</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XRC6</accession>
    <name>A0A0P6XRC6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF126 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_07975</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0107 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062460.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07975"/>
    <dbReference type="EnsemblBacteria" id="KPL77815">
        <property type="protein sequence ID" value="KPL77815"/>
        <property type="gene ID" value="ADN00_07975"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.595"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01356">
        <property type="entry name" value="AcnX_swivel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00078">
        <property type="entry name" value="UPF0107"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020794">
        <property type="entry name" value="AcnX_sub2_archaea_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012016">
        <property type="entry name" value="AcnX_sub2_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002840">
        <property type="entry name" value="AcnX_swivel_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01989">
        <property type="entry name" value="DUF126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004966">
        <property type="entry name" value="UCP004966"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF126" evidence="2">
        <location>
            <begin position="24"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="138" mass="14310" checksum="2E331800A4B28A63" modified="2016-01-20" version="1">MNLTGRTISNGQAQGSALVSQMGISFFGGVDPETGLVTETGHDLYGQSIAGKVLVFPTGKGSTVGSYTLYRLKANGLAPCAILNRECETITAVGCIISDIPCVDLLAIDQIQTGMQVAVNADEGIVTITQSPCLQETT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XRN4</accession>
    <name>A0A0P6XRN4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Isopentenyl phosphate kinase</fullName>
            <ecNumber evidence="3">2.7.4.26</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_08300</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + isopentenyl phosphate = ADP + isopentenyl diphosphate</text>
            <dbReference type="Rhea" id="RHEA:33963"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:65078"/>
            <dbReference type="ChEBI" id="CHEBI:128769"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.26"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the isopentenyl phosphate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.26" evidence="3"/>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08300"/>
    <dbReference type="EnsemblBacteria" id="KPL77916">
        <property type="protein sequence ID" value="KPL77916"/>
        <property type="gene ID" value="ADN00_08300"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.662"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102043">
        <property type="term" value="F:isopentenyl phosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008299">
        <property type="term" value="P:isoprenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04241">
        <property type="entry name" value="AAK_FomA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024192">
        <property type="entry name" value="Fosfomycin_R_FomA-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43654:SF1">
        <property type="entry name" value="PTHR43654:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF016496">
        <property type="entry name" value="Kin_FomA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0414">Isoprene biosynthesis</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_kinase" evidence="8">
        <location>
            <begin position="1"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="6"/>
            <end position="10"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="155"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="217"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="7">
        <location>
            <position position="15"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR016496-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR016496-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00696"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL77916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="265" mass="28938" checksum="7F7943A1CBDE1684" modified="2016-01-20" version="1">MLIFLKLGGSLITDKDRPKTARVDIINRLCGEIAAAKKEKPHLNIILGHGSGSFGHASARKYGTHGGVRSREEWLGFAEVWRDARELNQIVMSSLDEANLPAISFPPSAMVTTDHRKIITWDTQNIQSALQAGLLPVIMGDVIFDHGQGGTILSTEELFHYLALVIHPDRILYTGKDEGVWEDFPQSQKLISKITPQTFPQIQAAIQASASVDVTGGMLLKVQSMLHLVQQIPNLKVQIFSGLEAGNVHKALTGEELGTIISSGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XS35</accession>
    <name>A0A0P6XS35_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_12995</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000028">
        <property type="protein sequence ID" value="KPL75302.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063452.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000028.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12995"/>
    <dbReference type="EnsemblBacteria" id="KPL75302">
        <property type="protein sequence ID" value="KPL75302"/>
        <property type="gene ID" value="ADN00_12995"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005537">
        <property type="entry name" value="RAMP_III_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03787">
        <property type="entry name" value="RAMPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL75302.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="345" mass="39431" checksum="9C785320A469D2C4" modified="2016-01-20" version="1">MRKLLLNEFVLGLELKIIEDDLLLIGMPDPTQQKKKEDKADKYIPMRSSDGKYFIPGSSLKGVLRSRAEYIANIIHQGNGVCHIFDQRKKSEAHLPGRLCCGDRFEIRLKDAEKNQKTLPYATFYADACPACQLFGHSSFQGRLSVTDFPALDSDSGKPFSQTHIAVDRLTAGAAQSKLFTPKYLRDAVFKGSIHIQNFSIWQLGWLGFVLQDLREGLIRLGRKQTSGYGKLAIQKETVRFRYLGKPPTEEKLWGIGKYLNDEWIKQYGYGNGLAYESIDLPGAQWSTPDHLWYEYSAEAPPEPLPLWENARSAAYHYLQSFKFTPDMQLKSLQELWDRQREAAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-12-02" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XU15</accession>
    <name>A0A0P6XU15_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DUF5698 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_01965</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000007">
        <property type="protein sequence ID" value="KPL80061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061284.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000007.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80061">
        <property type="protein sequence ID" value="KPL80061"/>
        <property type="gene ID" value="ADN00_01965"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044035">
        <property type="entry name" value="DUF5698"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022930">
        <property type="entry name" value="UPF0316"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40060">
        <property type="entry name" value="PTHR40060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18955">
        <property type="entry name" value="DUF5698"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="40"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5698" evidence="6">
        <location>
            <begin position="28"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF18955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL80061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="181" mass="19729" checksum="94F8D381747FE106" modified="2016-01-20" version="1">METLLSPQVWLWALAIFGLRVVNISLDTVRFLLVLRGKKLLTWILGFIQSIMYVVVISEVLSSMDNVLNIVAYAAGYSTGTTIGMWIEKRLAIGHVQLNIVSTTLGSAVAAALRANGFAVTEVPARGKDGTVTLLHADVNRNDVDNAETVILEADPTAFITAEDVRPMRAGFWRSSPNSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUA9</accession>
    <name>A0A0P6XUA9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10235</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062904.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76957">
        <property type="protein sequence ID" value="KPL76957"/>
        <property type="gene ID" value="ADN00_10235"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="121" mass="12575" checksum="911BFB3625FC9BD9" modified="2016-01-20" version="1">MSTLKTIGVAALILAIFLSGYGLHRLGKPYHTLLFTLHKLVSLGALAWLLVTAARAQRAAPLPALAFSLVVAATVFFVATIATGGLVSLEKPAPAAVAWAHKLLPYLTAASSAAAWVSLSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUE3</accession>
    <name>A0A0P6XUE3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">HAD family hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_05895</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HAD-like hydrolase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062041.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="SMR" id="A0A0P6XUE3"/>
    <dbReference type="STRING" id="1134406.ADN00_05895"/>
    <dbReference type="EnsemblBacteria" id="KPL78766">
        <property type="protein sequence ID" value="KPL78766"/>
        <property type="gene ID" value="ADN00_05895"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1655"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006357">
        <property type="entry name" value="HAD-SF_hydro_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13344">
        <property type="entry name" value="Hydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000915">
        <property type="entry name" value="PGP-type_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01460">
        <property type="entry name" value="HAD-SF-IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="15"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR000915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000915-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="264" mass="29382" checksum="A28F383966E1D409" modified="2016-01-20" version="1">MNFEKLKKIRCYLLDMDGTIFLGGKLLPGAADFLELLRQRGIPFYFLTNNSSRSKIEYANKLSHLGIQAPENQIFTSGEATAIFINKQKPGARIFVVGTQPLEAEMRNHGFHLVEEQPDFVVLGFDTTLTYNKLWKLCDFVRAGVPYIATHPDYNCPTETGFMPDIGAMIAFVEASTGKCPDYIIGKPNLPVVEAMVEKTGYDVKELGMIGDRLYTDIALGRAGLTTVLVLSGETKSQDLLSSEFTPDYVMENLAELVEVYKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XV68</accession>
    <name>A0A0P6XV68_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glyco_hydro_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_09110</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyl hydrolase 3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09110"/>
    <dbReference type="EnsemblBacteria" id="KPL77359">
        <property type="protein sequence ID" value="KPL77359"/>
        <property type="gene ID" value="ADN00_09110"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4056"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019800">
        <property type="entry name" value="Glyco_hydro_3_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036881">
        <property type="entry name" value="Glyco_hydro_3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001764">
        <property type="entry name" value="Glyco_hydro_3_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036962">
        <property type="entry name" value="Glyco_hydro_3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00933">
        <property type="entry name" value="Glyco_hydro_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00133">
        <property type="entry name" value="GLHYDRLASE3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52279">
        <property type="entry name" value="SSF52279"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00775">
        <property type="entry name" value="GLYCOSYL_HYDROL_F3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_3" evidence="3">
        <location>
            <begin position="3"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL77359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="520" mass="55534" checksum="3AA57800EF2496DF" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XVQ0</accession>
    <name>A0A0P6XVQ0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_02860</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000013">
        <property type="protein sequence ID" value="KPL79388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061449.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000013.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79388">
        <property type="protein sequence ID" value="KPL79388"/>
        <property type="gene ID" value="ADN00_02860"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2207"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="61"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="96"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="138"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="179"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="266" mass="29371" checksum="98784C3599BF8174" modified="2016-01-20" version="1">MNLSSIRSNQQLMQALRKFRVSPGLLFGIIIFTALIAFEMFNYSTTDYALRDLLGDLKFMGIHWATILTIAFCGIDFAGIARLFTPEQGNNEPKEVWYLFGAWLLAATMNAILTWWGVSMAIMTHNVQSAAVLDAETLIDVVPVFVAIMVWVIRILIIGSLSMAGDRLIWHQAARSPRRSTALENAQSAHNPARPSQRPMPSMPMTASSAPRPASRAMPRPVPGNSPVPEITPNRAEPTYHSVNMASSESSAPIGDRSAYTHTRQM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XW73</accession>
    <name>A0A0P6XW73_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_14640</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000035">
        <property type="protein sequence ID" value="KPL73575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063775.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000035.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL73575">
        <property type="protein sequence ID" value="KPL73575"/>
        <property type="gene ID" value="ADN00_14640"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL73575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="89" mass="10280" checksum="1929DE4E0221BE99" modified="2016-01-20" version="1">MNMGMLWYDSNPQTDLPSKLSRAVSYYVEKYGKKPNLCFIHPSMLTDEKTRQLLPSLGVELKPNRLVLPHHFWIGVRDAVLNPPREDGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XWL7</accession>
    <name>A0A0P6XWL7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_08195</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77853">
        <property type="protein sequence ID" value="KPL77853"/>
        <property type="gene ID" value="ADN00_08195"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="366" mass="40359" checksum="C22A63CA4BCACD9D" modified="2016-01-20" version="1">MNNSQYRKIFIIVFATLLMAAAGWLLVKPLIERLQEASLTPADVAYLSPVNSPEIWLWRAAHGEAVPITQTQGRVFDFDVSPDGRFIVFSQTNEQGGRDLMRVQIVTRAESRLLACGQSLCFQPAISPDGKQVAYTVIDPQADAQAKAVQRVFVLDLAGRSQRALYEDETISASQPAWSPQGDRLAVVDEANREIRVISLSTGDTMTIPTQVSEMGAFSPDGAQMMFLNAQMTGIQSFQGVYLADFTDQQIRAVIAPYQSEVDFGVPAWSAANQKIAVNWRKMIGLGRGTEQISIFEADGSGEQVITTDQNFTHGAYSWSPDGSRLLYQQFEVGKTGAQPEVAIWEMATGEHKVIAQNAFFPRWVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XWM2</accession>
    <name>A0A0P6XWM2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">YkuD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_00045</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL80984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060913.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00045"/>
    <dbReference type="EnsemblBacteria" id="KPL80984">
        <property type="protein sequence ID" value="KPL80984"/>
        <property type="gene ID" value="ADN00_00045"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd16913">
        <property type="entry name" value="YkuD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005490">
        <property type="entry name" value="LD_TPept_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006311">
        <property type="entry name" value="TAT_signal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019546">
        <property type="entry name" value="TAT_signal_bac_arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038063">
        <property type="entry name" value="Transpep_catalytic_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03734">
        <property type="entry name" value="YkuD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141523">
        <property type="entry name" value="SSF141523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01409">
        <property type="entry name" value="TAT_signal_seq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51318">
        <property type="entry name" value="TAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="YkuD" evidence="3">
        <location>
            <begin position="216"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL80984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="360" mass="40249" checksum="16EAB17E6EE87DEA" modified="2016-01-20" version="1">MQNLSRRDFLKLSALGLGALAFRPWLDRVKFQSEFPEGELLGRNCTGGWISLRARPYSGSPEVERLYEDSLVVWNREVIGEAAMFARVNRWVETPKGYLYAANIQPVKNLPNVPLTELPLSSLGKGMWAEVTVPYVDLYLDRPACSPWLQEVSRPRLYYSQVMWIDDIVTNSQGQVLYRVNELYGNCGDIFWAAAEAFRPITEEELSPIHPDAADKRVVVDLNHQVLSCYEGKDEVYFCTVSTGAKYDAQGNVVDKWATPLGEHLPWRKSISIHMAGGATGAGYDTPGIPWSVLFDPNGAAIHSTFWHNAFGDARSHGCVNARPEDAKWIFRWTSPHVPYDPGDVDLTGKGGTIVDVIEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XYC0</accession>
    <name>A0A0P6XYC0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_07535</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78301">
        <property type="protein sequence ID" value="KPL78301"/>
        <property type="gene ID" value="ADN00_07535"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="103" mass="12307" checksum="AD5D8C4DB3868801" modified="2016-01-20" version="1">MYEGPEGRISYDMAWMYDEMYIQYIGNQVIYKPEHILRACPLEDQNIQQVLINYGSYDKYQFTDWIDLTQLTSLTPTDFFDVITGNVNQACFDLDYYKLFPQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y373</accession>
    <name>A0A0P6Y373_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_03235</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000014">
        <property type="protein sequence ID" value="KPL79352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03235"/>
    <dbReference type="EnsemblBacteria" id="KPL79352">
        <property type="protein sequence ID" value="KPL79352"/>
        <property type="gene ID" value="ADN00_03235"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="209" mass="24130" checksum="7659F4EA6DE606BC" modified="2016-01-20" version="1">MNTQMLYEIIGYAASTLVAISLTMSSILKLRVINLIGASIFTVYGLLIGAYPVAGLNFFIVLIDLYFLYEMRAAKEYFKLLDVRPQNNYFKEFLSHYQPELQKYFPGFEFKPEDQQIIFFVLRNMVPAGLFIGRVAGEDTLEVELDFVIPGYRDFKIGRYLYEKNAAFFLSKGIRRISTRAATEKHSRYLKRMGFLAGRDNQFLLTLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y5P3</accession>
    <name>A0A0P6Y5P3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_10005</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062860.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76921">
        <property type="protein sequence ID" value="KPL76921"/>
        <property type="gene ID" value="ADN00_10005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="41"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="105"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="179"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="210"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL76921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="230" mass="25063" checksum="CA3C5149EA2CF515" modified="2016-01-20" version="1">MDHPSQDLKDQSGSPTAGDQENSSATENAGDSKSDEASLQFILLVAFFVATIIGMVWVATQYVRYVNQILNISFWVTIGLSVFAVGLLAWAFVQKRAQDDFPAILVGFYSLWLCLVAGGLVYLIYAPPTAPADYESTFATLLNMDFQADNWMINALKIGFGGEDSPVDSTIEFIASQAFALPFMFLTFLAIFGIQANLAWAFIKKVPLQISIYLLAGALVTATISAIFLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y8B6</accession>
    <name>A0A0P6Y8B6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_08420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ROK (NagC/XylR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77918.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08420"/>
    <dbReference type="EnsemblBacteria" id="KPL77918">
        <property type="protein sequence ID" value="KPL77918"/>
        <property type="gene ID" value="ADN00_08420"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01125">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77918.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="379" mass="40085" checksum="D046523015486708" modified="2016-01-20" version="1">MGGIARVDLARELNLTRAAVTSIIQDLSKAGLVREVGSQPSGRKPVVLEINPNFGKVIGIDLGATHMTLIVANYAGQVIREVETPLEINDGPQVCLTHVIRQVRQTLHDLGVPLSEVKAVGMGVPGPVVSEKGMVSSPPIMPNWDHFPIRDYMAEQLGVPVTLGNDAELGALGEWAYGAGRGEKVLAYIKVGTGIGAGLLIDGKIFHGATGTAGEIGHIVIDRKGPKCTCGNYGCLEAFAGGRAIARRAQDFVRKNQRSRLAEIQPVEAIRAKDVIAAARRGDLPAQQIIKEVGYAVGSALSSLVNLFNPSMIVVGGQVSQCGDLFLEPMRKAVDEKSLRVAADHVCIAAAYLGRRSSGIGAVVEALTIALHQFADDNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YA39</accession>
    <name>A0A0P6YA39_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Acetyl xylan esterase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061952.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05400"/>
    <dbReference type="EnsemblBacteria" id="KPL78686">
        <property type="protein sequence ID" value="KPL78686"/>
        <property type="gene ID" value="ADN00_05400"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1554"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008391">
        <property type="entry name" value="AXE1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039069">
        <property type="entry name" value="CE7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40111">
        <property type="entry name" value="PTHR40111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05448">
        <property type="entry name" value="AXE1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AXE1" evidence="1">
        <location>
            <begin position="1"/>
            <end position="319"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="323" mass="36095" checksum="3DDE4D1E672D0374" modified="2016-01-20" version="1">MSQFDFPLSELEVYKPERTEPADFDAFWQKTLEAARAFPLDARFVPAEFGLETLDVWDVTFNGYAGQPIKAWMMIPKGQKSKLPCVVEFIGYGGGRSFPYHWLSFPSCGYAYLVMDTRGQGSVWSHGDTPDMDDSTSSPQVPGFMTRGILSPETYYYRRLMTDAVRAVETAASHPLVDADRVVVTGGSQGGGISLAVAGLAPSVLAAMPDVPFLCHYRRAVQIIDSYPYGEIVKFCHTHRDKVETVFHTLSYFDGLNFAVRAKAKALFSVGLRDETCPPSTVFAAYNHYAGEKEIRVYEFNNHEGGELFHLRQQIAFLKTIFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YAI9</accession>
    <name>A0A0P6YAI9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">FAD-binding FR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_06320</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="4">Binds 1 [2Fe-2S] cluster per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PyrK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06320"/>
    <dbReference type="EnsemblBacteria" id="KPL78887">
        <property type="protein sequence ID" value="KPL78887"/>
        <property type="gene ID" value="ADN00_06320"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006221">
        <property type="term" value="P:pyrimidine nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.240.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012165">
        <property type="entry name" value="Cyt_c3_hydrogenase_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037117">
        <property type="entry name" value="Dihydroorotate_DH_ele_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019480">
        <property type="entry name" value="Dihydroorotate_DH_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10418">
        <property type="entry name" value="DHODB_Fe-S_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006816">
        <property type="entry name" value="Cyc3_hyd_g"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3" id="KW-0249">Electron transport</keyword>
    <keyword evidence="4" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="FAD-binding FR-type" evidence="5">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="204"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="226"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR006816-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL78887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="241" mass="25712" checksum="0E5FAD29EE2FAF55" modified="2016-01-20" version="1">MENERARSLVFDRPLTHAQPGQYLMAWLPEVGEKPFSIAGSDPLKITVVAVGPVSQALCQLKIGERVWVRGPLGSGYQPGGRRHLLVGGGYGAAPLFYLAQTLLARGEEVQVCLGARGQADLMLVSAFESAGCRTRITTDDGSAGEKGLVTQAVQAAIETFSPDTVYACGPVPMLVAVARLCEEKSINCQLSWEALIRCGMGLCGSCELDPEICQQTGVPQGWLTCKDGPVFQKNNQNSLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YAZ8</accession>
    <name>A0A0P6YAZ8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_04320</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79097">
        <property type="protein sequence ID" value="KPL79097"/>
        <property type="gene ID" value="ADN00_04320"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="132"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="191"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="219"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="250"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="9"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="159"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="297" mass="32478" checksum="0C92348772D81848" modified="2016-01-20" version="1">MAAGMHKRWAYFLLTVFILGAAIKEVYAKLVLNVLDPFPFTLITSVVAQITALGVVGARALAWRQEEPRWDGPVWLRVTLLCLATFGALLFNNIATDLIGPVSYKIIDGISYPVFLVILAFFFLGEVISRRTLLAALIALAGFGVYYADQVPYLRVNLPGLMAAVISPFFFAISMVQIKWLLTRKIAPEKIVAARFSAITLAALFWLPGHFPRLAGETWLLVVLIGSVGLAGLFLILFEALKHIPATHMTVFSASTPLFSAITAYLLIPGTVYQLNHYLGLGIIVVGLASKVVEAEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YFL4</accession>
    <name>A0A0P6YFL4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SsrA-binding protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Small protein B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">smpB</name>
        <name evidence="4" type="ORF">ADN00_00030</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for rescue of stalled ribosomes mediated by trans-translation. Binds to transfer-messenger RNA (tmRNA), required for stable association of tmRNA with ribosomes. tmRNA and SmpB together mimic tRNA shape, replacing the anticodon stem-loop with SmpB. tmRNA is encoded by the ssrA gene; the 2 termini fold to resemble tRNA(Ala) and it encodes a 'tag peptide', a short internal open reading frame. During trans-translation Ala-aminoacylated tmRNA acts like a tRNA, entering the A-site of stalled ribosomes, displacing the stalled mRNA. The ribosome then switches to translate the ORF on the tmRNA; the nascent peptide is terminated with the 'tag peptide' encoded by the tmRNA and targeted for degradation. The ribosome is freed to recommence translation, which seems to be the essential function of trans-translation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="3">The tmRNA-SmpB complex associates with stalled 70S ribosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SmpB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL80981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060910.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00030"/>
    <dbReference type="EnsemblBacteria" id="KPL80981">
        <property type="protein sequence ID" value="KPL80981"/>
        <property type="gene ID" value="ADN00_00030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3402"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070929">
        <property type="term" value="P:trans-translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09294">
        <property type="entry name" value="SmpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00023">
        <property type="entry name" value="SmpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023620">
        <property type="entry name" value="SmpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000037">
        <property type="entry name" value="SsrA-bd_prot"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020081">
        <property type="entry name" value="SsrA-bd_prot_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30308">
        <property type="entry name" value="PTHR30308"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01668">
        <property type="entry name" value="SmpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74982">
        <property type="entry name" value="SSF74982"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00086">
        <property type="entry name" value="smpB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01317">
        <property type="entry name" value="SSRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL80981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="151" mass="17462" checksum="4F0B502C5C056B90" modified="2016-01-20" version="1">MGIKIVSRNRKANFEFFLLETYEAGIALMGSEIKSIRAGQMSLGEAYVRIDDGKEAWLVNAHIAPYEMANRFNHDPLRPRRLLLHRKEIRGIWNAVRQKGVTVIPVQVYLKDGRAKVEIAIAKGKKLYDKRQDIAKRDAERDLNRKFNIKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YFS2</accession>
    <name>A0A0P6YFS2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">PMT_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ADN00_00465</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060988.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00465"/>
    <dbReference type="EnsemblBacteria" id="KPL81045">
        <property type="protein sequence ID" value="KPL81045"/>
        <property type="gene ID" value="ADN00_00465"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038731">
        <property type="entry name" value="RgtA/B/C-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13231">
        <property type="entry name" value="PMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="16"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="85"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="110"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="173"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="197"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="258"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="290"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="314"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="341"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="domain" description="PMT_2" evidence="9">
        <location>
            <begin position="60"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL81045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="513" mass="57097" checksum="6F82144BAEAA6945" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GL46</accession>
    <name>A0A0N8GL46_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">tRNA-guanine transglycosylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_17545</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064348.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17545"/>
    <dbReference type="EnsemblBacteria" id="KPL71482">
        <property type="protein sequence ID" value="KPL71482"/>
        <property type="gene ID" value="ADN00_17545"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.576"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008479">
        <property type="term" value="F:queuine tRNA-ribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0101030">
        <property type="term" value="P:tRNA-guanine transglycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.105">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004803">
        <property type="entry name" value="TGT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036511">
        <property type="entry name" value="TGT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002616">
        <property type="entry name" value="tRNA_ribo_trans-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01702">
        <property type="entry name" value="TGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51713">
        <property type="entry name" value="SSF51713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00430">
        <property type="entry name" value="Q_tRNA_tgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00449">
        <property type="entry name" value="tgt_general"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TGT" evidence="4">
        <location>
            <begin position="6"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL71482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="368" mass="41845" checksum="29F73476D29CAA7F" modified="2016-01-20" version="1">MSRFPSELNLAHGRLDFPVFLPDATFGVVRAVDASDLEDCRVQALVMNTFHLMQKPGSSTISALGGLHRMSGWPRPIITDSGGFQAYSLIRQNAQFGQLTDKGLFFQPEGSSRKYQLTPEKTVQLQMSYGADVVICLDDCTHAENDPAEQRKSVDRTVAWAKRCKSEYARLVEQKKLNEQDRPRIFAVVQGGGSRDLRRECAERLLEIGFDGYGYGGWPLDGQGNLLEDMLAWTRELIPAEYPMHALGIGHPENVLACYKMGYGMFDCAMPTRDARHGRLYVFNFPADGDQSGLNEKWFKYLYIHDEKHLKGDQPLSPYCDCLTCRRYSAGYLRHLFKMNDSLYMRLATVHNLRFMTQLTERIRAGEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GLA9</accession>
    <name>A0A0N8GLA9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_15895</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL71986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064025.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15895"/>
    <dbReference type="EnsemblBacteria" id="KPL71986">
        <property type="protein sequence ID" value="KPL71986"/>
        <property type="gene ID" value="ADN00_15895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005077">
        <property type="entry name" value="Peptidase_C11"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37835">
        <property type="entry name" value="PTHR37835"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03415">
        <property type="entry name" value="Peptidase_C11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006025798" evidence="2">
        <location>
            <begin position="24"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL71986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="740" mass="81619" checksum="2D0FEC7732F67BD6" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GM54</accession>
    <name>A0A0N8GM54_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13675</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063585.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000032.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13675"/>
    <dbReference type="EnsemblBacteria" id="KPL74346">
        <property type="protein sequence ID" value="KPL74346"/>
        <property type="gene ID" value="ADN00_13675"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="215"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="291"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="323"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="351"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="376"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="541" mass="59588" checksum="FE28C3049FD72AE0" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMK2</accession>
    <name>A0A0N8GMK2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Helicase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_12880</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12880"/>
    <dbReference type="EnsemblBacteria" id="KPL75530">
        <property type="protein sequence ID" value="KPL75530"/>
        <property type="gene ID" value="ADN00_12880"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase C-terminal" evidence="2">
        <location>
            <begin position="636"/>
            <end position="801"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="494"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL75530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="880" mass="98059" checksum="F20B0EC64C43B2BB" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMR9</accession>
    <name>A0A0N8GMR9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_12015</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063258.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76066">
        <property type="protein sequence ID" value="KPL76066"/>
        <property type="gene ID" value="ADN00_12015"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="144"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="213"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="281"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="316"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="349"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="378"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="539" mass="58343" checksum="F318E22E1A306453" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GN42</accession>
    <name>A0A0N8GN42_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_10860</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063019.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10860"/>
    <dbReference type="EnsemblBacteria" id="KPL77050">
        <property type="protein sequence ID" value="KPL77050"/>
        <property type="gene ID" value="ADN00_10860"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007887">
        <property type="entry name" value="MecA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032710">
        <property type="entry name" value="NTF2-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005311">
        <property type="entry name" value="PBP_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036138">
        <property type="entry name" value="PBP_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05223">
        <property type="entry name" value="MecA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03717">
        <property type="entry name" value="PBP_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54427">
        <property type="entry name" value="SSF54427"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56519">
        <property type="entry name" value="SSF56519"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006025819" evidence="2">
        <location>
            <begin position="28"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="domain" description="MecA_N" evidence="5">
        <location>
            <begin position="53"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="domain" description="PBP_dimer" evidence="4">
        <location>
            <begin position="175"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="3">
        <location>
            <begin position="376"/>
            <end position="702"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF05223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL77050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="738" mass="80966" checksum="639E660001786858" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNJ1</accession>
    <name>A0A0N8GNJ1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">R3H domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_07145</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062295.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07145"/>
    <dbReference type="EnsemblBacteria" id="KPL78242">
        <property type="protein sequence ID" value="KPL78242"/>
        <property type="gene ID" value="ADN00_07145"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3247"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02414">
        <property type="entry name" value="jag_KH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02644">
        <property type="entry name" value="R3H_jag"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.30.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038008">
        <property type="entry name" value="Jag_KH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038247">
        <property type="entry name" value="Jag_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039247">
        <property type="entry name" value="KhpB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032782">
        <property type="entry name" value="KhpB_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001374">
        <property type="entry name" value="R3H_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036867">
        <property type="entry name" value="R3H_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034079">
        <property type="entry name" value="R3H_KhpB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35800">
        <property type="entry name" value="PTHR35800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14804">
        <property type="entry name" value="Jag_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01424">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01245">
        <property type="entry name" value="Jag_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00393">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82708">
        <property type="entry name" value="SSF82708"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51061">
        <property type="entry name" value="R3H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0133">Cell shape</keyword>
    <keyword evidence="5" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="R3H" evidence="7">
        <location>
            <begin position="184"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="68"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL78242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="251" mass="28339" checksum="8A711860FE520EF8" modified="2016-01-20" version="1">MSQEKTTLEIIAPTVEEAVQNGAAQLGLPVESMEVEVLDAGSKGIFGLGGRQARVRLSIKVLEQEPKAAQPVKSKPAAEPEIEEDEYEEPESEVTDEALAVSKKVVEDLLTRMKVHAQVKAMYQEQEEGEEPVLLVDVQGKDLSILIGRRSETLNALQYIANLIVGKQLGRWVPLVIDIQGYRSRRERQLRQLARRMADQAIHTNRRQILEPMPANERRLIHLELRNHPKVTTQSVGEEPYRKVSIFIKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNQ6</accession>
    <name>A0A0N8GNQ6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_05875</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="8">Binds 2 divalent metal cations per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the peptidase M42 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062037.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78762">
        <property type="protein sequence ID" value="KPL78762"/>
        <property type="gene ID" value="ADN00_05875"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008007">
        <property type="entry name" value="Peptidase_M42"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023367">
        <property type="entry name" value="Peptidase_M42_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05343">
        <property type="entry name" value="Peptidase_M42"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001123">
        <property type="entry name" value="PepA_GA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="206"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="207"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="229"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="323"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR001123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001123-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001123-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL78762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="350" mass="38160" checksum="FA54B866FCE3AD99" modified="2016-01-20" version="1">MPEFSVDLALLQTLTAIPGVSGREQPVAEFIQKNLPREFDCAIDGLGNLTAHLPGSGPKLVLLTHMDEVGLIVQQIKPNGFLSVERIGGISIRALPGSRMDLWTETGKLPAQIGLLPGHLDKGDPPKLESLYVDIGARSAQQAAEMGVQIGDVLTWPHQFQQTSPNRVSCKALDDRLGCFALMLLAQRVSNLQLNVDLTLAFSVQEENMLSGSLPIMRRIEPDIVIGIDGTLVFDTPDLDHQQSGIQLGCGPVLKWMDAIRGKLAAYLPDLRLSRQIRRLAINHNLPLQQEVMTGLTTAITPVPYQANGIRTAALSLPIRYHHTPIESADLDDLAVLIDLVQLVILENSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNS0</accession>
    <name>A0A0N8GNS0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">LacI family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05635</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05635"/>
    <dbReference type="EnsemblBacteria" id="KPL78874">
        <property type="protein sequence ID" value="KPL78874"/>
        <property type="gene ID" value="ADN00_05635"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1604"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025997">
        <property type="entry name" value="SBP_2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13407">
        <property type="entry name" value="Peripla_BP_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peripla_BP_4" evidence="1">
        <location>
            <begin position="30"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="316" mass="33099" checksum="8F8D306A7D8EA688" modified="2016-01-20" version="1">MLLSACQPAAPAPEEAAAPAAAEGKKLMCIIVPPVENPFFGTQQEIAAKKAEEMGYEALKLVHDDDANKQMELIETCIGKGAAAIILDNAGADATVAAVQKAKDAGIPTFLIDREITKEGVAVAQIVSNNYQGATILAEYFAQLMGEEGGYIELTGKDTDTNAHVRSQGYHDVLDQIPGMTMLAQQTANWSQTEGYSVMESLLQAHPEVKGVICGNDTMALGAQAALIAAGRTDVIVVGFDGSDDVNESILKGEIDAGALQPVAELATQAVIQADAFIKTGSTGKPEKQTIDMVLLTPENACQYTGFAPNGKTSCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNY4</accession>
    <name>A0A0N8GNY4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_02840</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000013">
        <property type="protein sequence ID" value="KPL79386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061446.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000013.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02840"/>
    <dbReference type="EnsemblBacteria" id="KPL79386">
        <property type="protein sequence ID" value="KPL79386"/>
        <property type="gene ID" value="ADN00_02840"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2201"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="109" mass="12303" checksum="BF02E070E7018043" modified="2016-01-20" version="1">MDMKNFTFVVTDWSRVEVTQHAGETGMATWRTQQFDGIRVRMVEYSPGYLADHWCAKGHILLVLEGELHTELKDGRKFVLSAGMTYQVGDNAEPHRSGAPFGAKLFIVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="36" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GPG5</accession>
    <name>A0A0N8GPG5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Bifunctional NAD(P)H-hydrate repair enzyme</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="16">Nicotinamide nucleotide repair protein</fullName>
        </alternativeName>
        <domain>
            <recommendedName>
                <fullName evidence="16">ADP-dependent (S)-NAD(P)H-hydrate dehydratase</fullName>
                <ecNumber evidence="16">4.2.1.136</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="16">ADP-dependent NAD(P)HX dehydratase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="16">NAD(P)H-hydrate epimerase</fullName>
                <ecNumber evidence="16">5.1.99.6</ecNumber>
            </recommendedName>
        </domain>
    </protein>
    <gene>
        <name evidence="14" type="primary">nnrD</name>
        <name evidence="15" type="synonym">nnrE</name>
        <name evidence="18" type="ORF">ADN00_01195</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="18 19" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="18 19">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13 16">Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.</text>
    </comment>
    <comment type="function">
        <text evidence="14">Catalyzes the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. Together with NAD(P)HX epimerase, which catalyzes the epimerization of the S- and R-forms, the enzyme allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration.</text>
    </comment>
    <comment type="function">
        <text evidence="15">Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epimers of NAD(P)HX.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(6R)-NADHX = (6S)-NADHX</text>
            <dbReference type="Rhea" id="RHEA:32215"/>
            <dbReference type="ChEBI" id="CHEBI:64074"/>
            <dbReference type="ChEBI" id="CHEBI:64075"/>
            <dbReference type="EC" id="5.1.99.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>(6R)-NADPHX = (6S)-NADPHX</text>
            <dbReference type="Rhea" id="RHEA:32227"/>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
            <dbReference type="ChEBI" id="CHEBI:64077"/>
            <dbReference type="EC" id="5.1.99.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>(6S)-NADHX + ADP = AMP + H(+) + NADH + phosphate</text>
            <dbReference type="Rhea" id="RHEA:32223"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:64074"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.2.1.136"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>(6S)-NADPHX + ADP = AMP + H(+) + NADPH + phosphate</text>
            <dbReference type="Rhea" id="RHEA:32235"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="4.2.1.136"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15 16">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="15 16">Binds 1 potassium ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="14">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="14">Belongs to the NnrD/CARKD family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="15">Belongs to the NnrE/AIBP family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 16">In the C-terminal section; belongs to the NnrD/CARKD family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 16">In the N-terminal section; belongs to the NnrE/AIBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.136" evidence="16"/>
    <dbReference type="EC" id="5.1.99.6" evidence="16"/>
    <dbReference type="EMBL" id="LGCL01000003">
        <property type="protein sequence ID" value="KPL80834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061135.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01195"/>
    <dbReference type="EnsemblBacteria" id="KPL80834">
        <property type="protein sequence ID" value="KPL80834"/>
        <property type="gene ID" value="ADN00_01195"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1987"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052855">
        <property type="term" value="F:ADP-dependent NAD(P)H-hydrate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052856">
        <property type="term" value="F:NADHX epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052857">
        <property type="term" value="F:NADPHX epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046496">
        <property type="term" value="P:nicotinamide nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01171">
        <property type="entry name" value="YXKO-related"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01965">
        <property type="entry name" value="NADHX_dehydratase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01966">
        <property type="entry name" value="NADHX_epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017953">
        <property type="entry name" value="Carbohydrate_kinase_pred_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000631">
        <property type="entry name" value="CARKD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030677">
        <property type="entry name" value="Nnr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004443">
        <property type="entry name" value="YjeF_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036652">
        <property type="entry name" value="YjeF_N_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01256">
        <property type="entry name" value="Carb_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03853">
        <property type="entry name" value="YjeF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017184">
        <property type="entry name" value="Nnr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64153">
        <property type="entry name" value="SSF64153"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00196">
        <property type="entry name" value="yjeF_cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01050">
        <property type="entry name" value="YJEF_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51383">
        <property type="entry name" value="YJEF_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51385">
        <property type="entry name" value="YJEF_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 14 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 15 16" id="KW-0413">Isomerase</keyword>
    <keyword evidence="12 14 16" id="KW-0456">Lyase</keyword>
    <keyword evidence="15 16" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10 14 16" id="KW-0520">NAD</keyword>
    <keyword evidence="9 14 16" id="KW-0521">NADP</keyword>
    <keyword evidence="7 14 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15 16" id="KW-0630">Potassium</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YjeF N-terminal" evidence="17">
        <location>
            <begin position="9"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="NADPHX" evidence="15">
        <location>
            <begin position="58"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="NADPHX" evidence="15">
        <location>
            <begin position="130"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="59"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="329"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="405"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="442"/>
            <end position="446"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="471"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="472"/>
        </location>
        <ligand>
            <name>(6S)-NADPHX</name>
            <dbReference type="ChEBI" id="CHEBI:64076"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00009524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00025153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRNR" id="PIRNR017184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="EMBL" id="KPL80834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="532" mass="55365" checksum="01F7D7C2E8B2A9F6" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GPK0</accession>
    <name>A0A0N8GPK0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_00905</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061066.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00905"/>
    <dbReference type="EnsemblBacteria" id="KPL81114">
        <property type="protein sequence ID" value="KPL81114"/>
        <property type="gene ID" value="ADN00_00905"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="20"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="607"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="1512"/>
            <end position="1545"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="1716"/>
            <end position="1749"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="1750"/>
            <end position="1783"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL81114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="1802" mass="202707" checksum="B5D5C40391032441" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WMR5</accession>
    <name>A0A0P6WMR5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_18800</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064578.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70094">
        <property type="protein sequence ID" value="KPL70094"/>
        <property type="gene ID" value="ADN00_18800"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="87" mass="10134" checksum="EB3AA55A5BE12549" modified="2016-01-20" version="1">MIGNIPLKILLLIWWLQRKYVIGIKPLNIEKRLRMLNEIYYSLPVVQLNDWLGGRCVEKVITWIDCEKQSLIELQSLGVQASGVIKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WN12</accession>
    <name>A0A0P6WN12_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">ADN00_16935</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064234.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16935"/>
    <dbReference type="EnsemblBacteria" id="KPL71387">
        <property type="protein sequence ID" value="KPL71387"/>
        <property type="gene ID" value="ADN00_16935"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.446"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd04590">
        <property type="entry name" value="CBS_pair_CorC_HlyC_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002550">
        <property type="entry name" value="CNNM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044751">
        <property type="entry name" value="Ion_transp-like_CBS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005170">
        <property type="entry name" value="Transptr-assoc_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03471">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01595">
        <property type="entry name" value="DUF21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01091">
        <property type="entry name" value="CorC_HlyC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51846">
        <property type="entry name" value="CNNM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0129">CBS domain</keyword>
    <keyword evidence="6 8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 8 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="60"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="104"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="domain" description="CNNM transmembrane" evidence="11">
        <location>
            <begin position="1"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="10">
        <location>
            <begin position="220"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="10">
        <location>
            <begin position="281"/>
            <end position="340"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KPL71387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="444" mass="48341" checksum="95569028F5089694" modified="2016-01-20" version="1">MNDILVQILIIAVLIVLNGIFAMSEIALVSARKIRLQQRADDGDASAAVALEMAESPNRLLSTVQVGISLVGVFSGAVGGATLAKYLAPQIARIQILAPYSEGLSLVIVVLIITYFSLVVGELIPKRLAMGNPEKIATTVARPMRTLSALTAPIVNLLSASTELGLRLLGAKPNQEPPITEEEIKVLIEQGTQSGIFIEQEQDFVESVFRLANRRVDAIMTPYTEIEWLDINDSFEENLSLLLENRFTRWPVARGGLDNVIGILNARDLLAATLQEDPVEIEPLLLPALFVPESMPALKAFEEIKANPANVALVIDEFGGLIGMVTLLDILEAIVGEIPQAGKKEDPQIVQRADGSWLLDGLLQVDELKELLDIEDLPDEDRVGYQTLGGMVMAQFGSIPAAGDVFRWQEYKFEVVDMDGRRVDKVLVTLIADEENGKIVAGTD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WPU2</accession>
    <name>A0A0P6WPU2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Sugar ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_16600</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064159.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72091">
        <property type="protein sequence ID" value="KPL72091"/>
        <property type="gene ID" value="ADN00_16600"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3762"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="6"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="255"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL72091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="502" mass="56115" checksum="6DD339AEC2144014" modified="2016-01-20" version="1">MSSAIVQMQGITKSFNNIPVLNQVNFELLTGEVHALLGENGAGKSTLMKILRGVYEADAGEIVIQGQPVQFHSSKDARASGISMVFQEFSLIPTLTVAQNIFLTREARGKFGLLDDRECERRSKLLFDDMEVAIDPRATVETLSTGFRQLTEIATALSQEARILILDEPTASLAHTETLALFKLIRRLKEKGISIIYISHRMEEIFQIADRITVLRDGHNIITDEVSKLTIQEVIEHILGRKAEKTLQWEESAQVENPKILLNVKNLSCNRGVNDVSFSLYKGEVLGLAGLMGSGRTELVQAIFGMNPAKSGEVHVNGRKENIESPEGAMRARIALIPEDRRLQGLILMHSIKDNFVLPMIQLNRLTRRKLIVDDQKGNQLSQYYLEKLKIRSDSINKIVGLLSGGNQQKVVISKWLCTEPDILLMDEPTAGVDIGTKSEIIEMIRQLAREGKGVIFISSELQELLAVCDRILVIKQGKIEQELHRKEISSEERLHQILQGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WSM9</accession>
    <name>A0A0P6WSM9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_15975</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL71996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064039.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL71996">
        <property type="protein sequence ID" value="KPL71996"/>
        <property type="gene ID" value="ADN00_15975"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="130"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="210"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="239"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="324"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="382"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="432"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="453"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="604"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="628"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="659"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="703"/>
            <end position="723"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL71996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="870" mass="96914" checksum="34136220BED7B00A" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WSU5</accession>
    <name>A0A0P6WSU5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_16640</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064165.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72096">
        <property type="protein sequence ID" value="KPL72096"/>
        <property type="gene ID" value="ADN00_16640"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3771"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13477">
        <property type="entry name" value="Glyco_trans_4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="2"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="184"/>
            <end position="350"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL72096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="375" mass="41724" checksum="AB4D45A9E6B3F964" modified="2016-01-20" version="1">MKIVLFSNTAWYLYNFRLPLAKALRQRGDEVIFLSPPSEEGDYDQRLLNAGFRWMPFEFSRKGMNPLQDGMSIFRLARLYLGLQPDLVHQFTIKPVLYGSIAARMARIPHVVNSITGLGYIFADSSLKVKIVRQLVKLLYKFGTRGALMIFQNPEDQELFVSKGWTSPRRSVLIRGSGADTARFQPSSIPTGVPVVVMAARLIYDKGVTDFIEAAALLKQRGVQARFQLVGTPDLDNPNSVRPDEIQAWEQAGLVEYLGWQEDMAPIYQSATIICQPSAYREGVPKTLLEAAASARPLVATDIPGCREIVRQGENGFLVPVHDAPALANALQALIESPELCAQMGLKGREIVEHEFSQDINISQTIEVYRALTAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WVP5</accession>
    <name>A0A0P6WVP5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pseudouridine synthase</fullName>
            <ecNumber evidence="3">5.4.99.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_13585</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the pseudouridine synthase RsuA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.-" evidence="3"/>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063568.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000032.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13585"/>
    <dbReference type="EnsemblBacteria" id="KPL74331">
        <property type="protein sequence ID" value="KPL74331"/>
        <property type="gene ID" value="ADN00_13585"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1293"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120159">
        <property type="term" value="F:rRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042092">
        <property type="entry name" value="PsdUridine_s_RsuA/RluB/E/F_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000748">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB/E/F"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018496">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01479">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00093">
        <property type="entry name" value="TIGR00093"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01149">
        <property type="entry name" value="PSI_RSU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S4" evidence="5">
        <location>
            <begin position="3"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="237"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="296"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008348"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL74331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="315" mass="34986" checksum="2BDCED3A647042BE" modified="2016-01-20" version="1">MEERVQKILAQLGYGSRRSCEELIIQGRVTVNGAIVEIGSKAESGRDKIAVDGKDVPATAPKPVYIMVHKPQYVLSVQDESDQRRKVFDLVPDFGHLFAVGRLDFDSEGLMLLTNDGELANRLTHPRYGHEKEYKVLVIGEPDGQQLRAWRSGVVLEDGYRTQPATVEVNHTDRGETWLTVTMKEGRKRQIREVGARIGLPVKRIIRVRLANLELGKLKVGQWRHLTAQEELSLKRTAGIKPESMAGRKTARPVGPARKPMGKPGAKPAGKPTGKPAEKPARRPVGKPTSKPDGKPVAKPTDKPGERTKRFRRDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WVS2</accession>
    <name>A0A0P6WVS2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Lactamase_B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_18450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064520.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18450"/>
    <dbReference type="EnsemblBacteria" id="KPL70041">
        <property type="protein sequence ID" value="KPL70041"/>
        <property type="gene ID" value="ADN00_18450"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="14"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="215" mass="23383" checksum="8D864DEAFC7193B3" modified="2016-01-20" version="1">MPLEIIERTFGPVQNNTYLLADTGQKRAVIIDPTFRPVMLQADLENHGLHLDAIWLTHAHFDHLGGVEALLAENPPPVQVGLHPADLPLWQSDAGAGLFGQPFSMNVEPDLLLTDGQELYVGEYPVKVLHTPGHSPGHVIFYIPSLSTAIVGDLIFRGGVGRTDLPGGDSYTLIKSIQEKILTLPDETVLLPGHGPSTTVELERDSNPYLNGFAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WVU0</accession>
    <name>A0A0P6WVU0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">3'-5' exonuclease DinG</fullName>
            <ecNumber evidence="5">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">dinG</name>
        <name evidence="8" type="ORF">ADN00_18595</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">3'-5' exonuclease.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the helicase family. DinG subfamily. Type 2 sub-subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="5"/>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064541.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18595"/>
    <dbReference type="EnsemblBacteria" id="KPL70060">
        <property type="protein sequence ID" value="KPL70060"/>
        <property type="gene ID" value="ADN00_18595"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3028"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008408">
        <property type="term" value="F:3'-5' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016818">
        <property type="term" value="F:hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02206">
        <property type="entry name" value="DinG_exonucl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006555">
        <property type="entry name" value="ATP-dep_Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010614">
        <property type="entry name" value="DEAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006310">
        <property type="entry name" value="DinG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045028">
        <property type="entry name" value="DinG/Rad3-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006054">
        <property type="entry name" value="DnaQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Exonuclease_RNaseT/DNA_pol3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014013">
        <property type="entry name" value="Helic_SF1/SF2_ATP-bd_DinG/Rad3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006554">
        <property type="entry name" value="Helicase-like_DEXD_c2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11472">
        <property type="entry name" value="PTHR11472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06733">
        <property type="entry name" value="DEAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13307">
        <property type="entry name" value="Helicase_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00488">
        <property type="entry name" value="DEXDc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00491">
        <property type="entry name" value="HELICc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01407">
        <property type="entry name" value="dinG_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00573">
        <property type="entry name" value="dnaq"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51193">
        <property type="entry name" value="HELICASE_ATP_BIND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="1 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="247"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="6">
        <location>
            <begin position="269"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="282"/>
            <end position="289"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL70060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="931" mass="103717" checksum="FABECA04A0BA21CF" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WX14</accession>
    <name>A0A0P6WX14_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_13290</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74815.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063508.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000031.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13290"/>
    <dbReference type="EnsemblBacteria" id="KPL74815">
        <property type="protein sequence ID" value="KPL74815"/>
        <property type="gene ID" value="ADN00_13290"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1240.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003759">
        <property type="entry name" value="Cbl-bd_cap"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006158">
        <property type="entry name" value="Cobalamin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036724">
        <property type="entry name" value="Cobalamin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036594">
        <property type="entry name" value="Meth_synthase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02310">
        <property type="entry name" value="B12-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02607">
        <property type="entry name" value="B12-binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52242">
        <property type="entry name" value="SSF52242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51332">
        <property type="entry name" value="B12_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="1">
        <location>
            <begin position="12"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="B12-binding" evidence="2">
        <location>
            <begin position="193"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL74815.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="324" mass="36949" checksum="1F4C73A98135E1B0" modified="2016-01-20" version="1">MSSIVELPDDPKYRIKAVSSKTGIRPVTLRAWERRHEILEPHRADNQYRLYSDRDIAILRWIKSRVDRGIPISSAVAELKSMQRIGSWPDALPQSPLIQRQKDNSVPPEFYSTHLFDALINHEEERVNELFDEMIKSFDLNSLLHEIICPTLVQIGEAWYHGRIRISTEHYASNIIQGKLLNLMDTFPTNRSAPLILVGSGPDERHEIGSLMLGLLLRQSGFRVEYLGADLPLEDLAEYAAYEKPRMIILSATLKETAIRLKPMQALLKKIRPKVYFGYGGSAFNEHPELQQEVPGIFLGNSMQLAVENVLKLFDIKVKEAQPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X031</accession>
    <name>A0A0P6X031_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_12965</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75547.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063443.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000027.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL75547">
        <property type="protein sequence ID" value="KPL75547"/>
        <property type="gene ID" value="ADN00_12965"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL75547.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="87" mass="9396" checksum="ADCD5EB3DAA0057E" modified="2016-01-20" version="1">MQISSPLSLRATPETGQASYLYDGDGNLARGIVNGVVTFYPGRHYNRAVDGANVTVKKFYTLGSTTVAVRTVQGSTDTLNWILSDCH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X0K2</accession>
    <name>A0A0P6X0K2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">3-oxoacyl-ACP reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063609.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000032.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13810"/>
    <dbReference type="EnsemblBacteria" id="KPL74364">
        <property type="protein sequence ID" value="KPL74364"/>
        <property type="gene ID" value="ADN00_13810"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1339"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="232"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="263" mass="27966" checksum="1B34188C3BD0F7DF" modified="2016-01-20" version="1">MDLKLKDKVALITGSSKGLGYATALKLAEEGARVAINSRNPEALQTAANQIRQQTGAEVLALPGDVTQPDLPAHLVEQVLGHFGRLDLLVCNAGGPPSGEFESFTDEQWHQAVELSFLSQVRLIRAALPALRQSECASVLTITSYSVKQPIPNLVLSNSVRAATVGLTKSLALELGSEGIRFNSILPAWTETQRVYDLMNARAASTGRSVEEEIALQAVSSPMGRMATPEEFANAAVFLLSPAASYITGVMLSVDGGMYKGTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X175</accession>
    <name>A0A0P6X175_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Probable dual-specificity RNA methyltransferase RlmN</fullName>
            <ecNumber evidence="11">2.1.1.192</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">23S rRNA (adenine(2503)-C(2))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">23S rRNA m2A2503 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Ribosomal RNA large subunit methyltransferase N</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">tRNA (adenine(37)-C(2))-methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">tRNA m2A37 methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">rlmN</name>
        <name evidence="13" type="ORF">ADN00_14815</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Specifically methylates position 2 of adenine 2503 in 23S rRNA and position 2 of adenine 37 in tRNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>adenosine(2503) in 23S rRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 2-methyladenosine(2503) in 23S rRNA + 5'-deoxyadenosine + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42916"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10152"/>
            <dbReference type="Rhea" id="RHEA-COMP:10282"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74497"/>
            <dbReference type="EC" id="2.1.1.192"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>adenosine(37) in tRNA + 2 reduced [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = 2-methyladenosine(37) in tRNA + 5'-deoxyadenosine + L-methionine + 2 oxidized [2Fe-2S]-[ferredoxin] + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:43332"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10485"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74497"/>
            <dbReference type="EC" id="2.1.1.192"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="11">Binds 1 [4Fe-4S] cluster. The cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="11">Reaction proceeds by a ping-pong mechanism involving intermediate methylation of a conserved cysteine residue.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the radical SAM superfamily. RlmN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.192" evidence="11"/>
    <dbReference type="EMBL" id="LGCL01000036">
        <property type="protein sequence ID" value="KPL73064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063812.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000036.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14815"/>
    <dbReference type="EnsemblBacteria" id="KPL73064">
        <property type="protein sequence ID" value="KPL73064"/>
        <property type="gene ID" value="ADN00_14815"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1826"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070040">
        <property type="term" value="F:rRNA (adenine-C2-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002935">
        <property type="term" value="F:tRNA (adenine-C2-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070475">
        <property type="term" value="P:rRNA base methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01849">
        <property type="entry name" value="RNA_methyltr_RlmN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040072">
        <property type="entry name" value="Methyltransferase_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027492">
        <property type="entry name" value="RNA_MTrfase_RlmN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004383">
        <property type="entry name" value="rRNA_lsu_MTrfase_RlmN/Cfr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30544">
        <property type="entry name" value="PTHR30544"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006004">
        <property type="entry name" value="CHP00048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00275">
        <property type="entry name" value="adenosine_C2_methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00048">
        <property type="entry name" value="rRNA_mod_RlmN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 11" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="3 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="9 11" id="KW-0408">Iron</keyword>
    <keyword evidence="10 11" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 11 13" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="7 11" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 11 13" id="KW-0808">Transferase</keyword>
    <keyword evidence="11" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="Radical SAM core" evidence="12">
        <location>
            <begin position="102"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="11">
        <location>
            <begin position="166"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="11">
        <location>
            <begin position="221"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="11">
        <location>
            <position position="96"/>
        </location>
    </feature>
    <feature type="active site" description="S-methylcysteine intermediate" evidence="11">
        <location>
            <position position="340"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="116"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="198"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="297"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KPL73064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="359" mass="40708" checksum="446E82E23D90E974" modified="2016-01-20" version="1">METNRKLLIYDLSLEELAELLQAWGEPKFRAAQIWNGLYQQLWSSWDEFTNLPLGLRQKLQANLSIQSLTPDRVLRSSDGETVKTLFKLEDQLAIEAVLMHYDERRTLCISTQAGCAMGCVFCATGQMGFKRNLSSGEIIEQVLYYARELQKMGEKVTNIVYMGMGEPFHNYQATMDSIDRLNHPQGMNLGERRFTISTVGLVSKIRRFADEKRQINLAISLHAADNPTRSALLPVNRRWPIETLMDAVRYYIEQTHRRVTFEWALIENQTDTPEQARQLAALLKGTLCHVNAIPLNPTRQFTGQAAGRERAETFRAILEKAGVPCTIRMRRGIDIQAGCGQLATESLNNPSSNVIISD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X265</accession>
    <name>A0A0P6X265_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">DUF2179 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_14750</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000035">
        <property type="protein sequence ID" value="KPL73604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14750"/>
    <dbReference type="EnsemblBacteria" id="KPL73604">
        <property type="protein sequence ID" value="KPL73604"/>
        <property type="gene ID" value="ADN00_14750"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019264">
        <property type="entry name" value="DUF2179"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003740">
        <property type="entry name" value="YitT"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10035">
        <property type="entry name" value="DUF2179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02588">
        <property type="entry name" value="YitT_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006483">
        <property type="entry name" value="Membrane_protein_YitT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2179" evidence="8">
        <location>
            <begin position="216"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF10035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL73604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="284" mass="30739" checksum="CAC5C5B3B54031DA" modified="2016-01-20" version="1">MQDYLLIFLGALVQALAMRLFLVPALLVSGGISGLAQVINYFTGWSIGIMVLIGNAPLFLLGWRYLGGRRFATRTVWAIVIFSVLTDLLAWVIPPAGVTDDLVLNSLYGGLVFGVGLGLVYRGKGTSGGSDILGLILYRRKGISMTQAYLLTDAITVLAGGLAWNWELALYGMVVIYVSGIAAELASEGLGTLRTAMIVTNMPDEISARVMEVLERGVTILPGTGAYTHQSRPVLYCVITRSEVNQLKELVREVDAKAFMVIGQAHEALGEGFKPLKPEERMEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X2E7</accession>
    <name>A0A0P6X2E7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_14495</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000034">
        <property type="protein sequence ID" value="KPL73768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063743.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000034.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL73768">
        <property type="protein sequence ID" value="KPL73768"/>
        <property type="gene ID" value="ADN00_14495"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL73768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="277" mass="31572" checksum="5F4AABF12E1B39E5" modified="2016-01-20" version="1">MNMPGEDWKQTDAGGLSVYFHAEDALDAQVIAQACRDSLPLLQEEWGLALARGCRVYVMTDWREFIFNSAPPLRRLIYALGYPLWARRMRAMWTYVGGWTVPYPGRPVVGVKPARLVAASDRTIGQSIFVEQPDSQLKIRSLAAHELAHAAAAHLRLPAWLNEGLAMRTADLALGRDTVRTDTLQLLKKPRRGPRAWLLMNTNLYFRGTDDIIYRYARGYWLTRYLQAVNSPALKAALRRRLPRRILYARLAEAVGLTAGMFWKRIDRLVYDHFSGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X2F8</accession>
    <name>A0A0P6X2F8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_14615</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000035">
        <property type="protein sequence ID" value="KPL73571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14615"/>
    <dbReference type="EnsemblBacteria" id="KPL73571">
        <property type="protein sequence ID" value="KPL73571"/>
        <property type="gene ID" value="ADN00_14615"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011249">
        <property type="entry name" value="Metalloenz_LuxS/M16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011765">
        <property type="entry name" value="Pept_M16_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007863">
        <property type="entry name" value="Peptidase_M16_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00675">
        <property type="entry name" value="Peptidase_M16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05193">
        <property type="entry name" value="Peptidase_M16_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63411">
        <property type="entry name" value="SSF63411"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M16" evidence="1">
        <location>
            <begin position="19"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M16_C" evidence="2">
        <location>
            <begin position="170"/>
            <end position="358"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05193"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL73571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="429" mass="48673" checksum="6D5A03F5DBCD77F4" modified="2016-01-20" version="1">MMKNGVTKIQLANGLTVHLKEIHSAPLISHWVWYKVGARDEETGRTGLSHWVEHMQFKGTHKYPAGELDKAISREGGEWNAMTSLDWTAFYEKLPTDRIDLALDLEADRMVNSRFDPEEVESERTVIISEREGHENEPLFRLDEAVQRLAFDRHPYRIEVIGEMEDLRRITRDDLYNHYRRYYTPDNAVLALAGDFSTDEMLKKVEQVYGSLPAGGAVKRAVECEPPLQEERRVTVTGPELTSYLRISYRSPQATHSDFFPFLIADSLLAGPAGLNRFGGGGITNKTSRLYQALVERELAVVVGAGLQATLDPYLYDVTAIVHPAQTPETVLAVYDDEIKRLQDQPVSAEEIARAVKQARAMFVYGSENISNQAFWMGYAEMFASYAWFENYLDELEKTTPADVQRIAQTYLLPERRVVGAYLPEGKEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X2Q7</accession>
    <name>A0A0P6X2Q7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltransf_11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10405</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062935.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10405"/>
    <dbReference type="EnsemblBacteria" id="KPL76982">
        <property type="protein sequence ID" value="KPL76982"/>
        <property type="gene ID" value="ADN00_10405"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2547"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="27"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="203" mass="23017" checksum="FE48790DF79E92CC" modified="2016-01-20" version="1">MNNTLYPAPLYTFLSLCQREALPKEVLDCGAGGANPPLNLFCAYGYRAAGVEIDPQRAQLAREAARQHGFTVDIREADMRRLPFADQSFSFVYSYNSVFHLSKADIAAAIAEMRRVLRPGGLFYVNFLSVDDGGFGEGQPLEKGEFLQEEDRGLVLHSYFEDDEGDCYFDGMQTLIKEKRARRQLHSDGQVYRMAFLDYMLRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X3X3</accession>
    <name>A0A0P6X3X3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_12005</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063256.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12005"/>
    <dbReference type="EnsemblBacteria" id="KPL76064">
        <property type="protein sequence ID" value="KPL76064"/>
        <property type="gene ID" value="ADN00_12005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="273" mass="29340" checksum="30988FCFAC3C5F43" modified="2016-01-20" version="1">MGTIMDKFDLSGRTAVVTGGVGLLGKGFCRTLAEAGANVVVADLNEEKAAAYAEELKESGYSALGVGLDVTQPESNDKMVARSVEKFGRLDVVVCSAAMDPKFDASQAGQHNNSFEDYPLAAWQSALDVNLTGMFLSVQASVKPMVKQGKGSIILICSTYGLVGPDQRIYEKPGQPKQYKPIFYTVTKAGVLGMCKYLSTYYAGTDIRVNCLTPGGVYNSHDETFTRNYSYRAVMGRMANLDEMNGGLLFLASDASSYMTGSNLVIDGGWTAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5D8</accession>
    <name>A0A0P6X5D8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_18960</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18960"/>
    <dbReference type="EnsemblBacteria" id="KPL70123">
        <property type="protein sequence ID" value="KPL70123"/>
        <property type="gene ID" value="ADN00_18960"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029432">
        <property type="entry name" value="Sipho_Gp37"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14594">
        <property type="entry name" value="Sipho_Gp37"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="286" mass="32144" checksum="1D4FAF809A99F668" modified="2016-01-20" version="1">MVGGPDENAFLSDRIVYPAPDGNFISQAHDSASGPLETVLKHFVTNNLGPGALPTRQILSIQVDLARGNYVERNGRFQNLLELLQETVLQSGTELGFQVRNRVFEVFLPSDKRGEVVFSLGLGTMLEFDYTLESAKANAVICGASGELTSRIVREVSWNQSVNQFGRIESFRDRRDTDQEDEIHQTLTEELVKNSERFSLQFRVAELEGLKAFDHWNIGDLVTVMIDGQRIEQAIREIHVKVDQKNGETIIPVVGTPGMGAVNFMSGLFERMRDIRRRVDHLEVIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5T3</accession>
    <name>A0A0P6X5T3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_12660</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063386.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000027.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12660"/>
    <dbReference type="EnsemblBacteria" id="KPL75496">
        <property type="protein sequence ID" value="KPL75496"/>
        <property type="gene ID" value="ADN00_12660"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014942">
        <property type="entry name" value="AbiEii"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08843">
        <property type="entry name" value="AbiEii"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL75496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="277" mass="31906" checksum="131784D15FBC77C5" modified="2016-01-20" version="1">MATLIQLMQNVLSKKDPLLPNETKRVILKEFLQAYTLDFLYNHPVYRKLNFYGGTCLHVIYNLNRLSEDIDLDNSSGIDLSVLENDLLTFYRSTIGYADVTAKTQIGEWGVRRTTLKLPILYALGLTSHANEPLHLKVEVSQHRQISIIRKTPVLLFGRSFVAAHFSLETMMAGKMLACLERNFQKGEGSAIKGRDFYDLLWFMQQKIMPLEEKLAKDGRQSYTIPSAMELLGEKVAEMKLSDLAEDLLPLFEQRSFIEAWLEGFKENFRAYVKSYY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5U3</accession>
    <name>A0A0P6X5U3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Flavodoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_12775</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Low-potential electron donor to a number of redox enzymes.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the flavodoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063408.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000027.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12775"/>
    <dbReference type="EnsemblBacteria" id="KPL75515">
        <property type="protein sequence ID" value="KPL75515"/>
        <property type="gene ID" value="ADN00_12775"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1252"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009399">
        <property type="term" value="P:nitrogen fixation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001094">
        <property type="entry name" value="Flavdoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001226">
        <property type="entry name" value="Flavodoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010086">
        <property type="entry name" value="Flavodoxin_lc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038996">
        <property type="entry name" value="FldA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00369">
        <property type="entry name" value="FLAVODOXIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01752">
        <property type="entry name" value="flav_long"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00201">
        <property type="entry name" value="FLAVODOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0288">FMN</keyword>
    <keyword evidence="4" id="KW-0535">Nitrogen fixation</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="6">
        <location>
            <begin position="4"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005267"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRNR" id="PIRNR038996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL75515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="172" mass="18613" checksum="88621FA1243FF37D" modified="2016-01-20" version="1">MAKIGLFYGSTTGNTEQDAQLIQKEFDKHQPGLVDLFNVAGDPLTKMNDYSLLIWGCSSWGAGEMQDDWDSAWKTLKTLSFAGKKVALFGLGDSVGFSDTFQDALALLAEAARKQGAELVGMWPTDDYSFDASAAVEGDMFVGLALDDDNEAGKTPQRVAAWVQQLIAEFGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5V6</accession>
    <name>A0A0P6X5V6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_09320</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062720.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77317">
        <property type="protein sequence ID" value="KPL77317"/>
        <property type="gene ID" value="ADN00_09320"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL77317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="260" mass="30228" checksum="0400BCD6A3C48557" modified="2016-01-20" version="1">MIKDNIKFELDKGYIKKSPVNNGASLEIASSISAYSLAKRSGLFSVPEVLEFDLEANEIVFEYIQNISPVGSLLHHLGDEKLAEIFFRVGQILRYIHLSLEPDCGRYLIPKSIDFEGWKTFLHGDFNLINVQYDLLRDHIVILDWSLTPLLKKSANWGTHFWDIAWMINSIFCSPPYLTNDYLYRKMLAESFLLGYQQNSSNVIDKKAFSLYCQNVFELFLKKFQQRTDFLHQIVQLPNRFMFEKFSLSLGKEVNSLLCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X715</accession>
    <name>A0A0P6X715_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_06425</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062135.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06425"/>
    <dbReference type="EnsemblBacteria" id="KPL78847">
        <property type="protein sequence ID" value="KPL78847"/>
        <property type="gene ID" value="ADN00_06425"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="5">
        <location>
            <begin position="7"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="4">
        <location>
            <begin position="118"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL78847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="334" mass="37961" checksum="91F9B52DA6BA32D2" modified="2016-01-20" version="1">MNETTPLSLQDAIQNYLTLVEQSRSKRTFLTYQNALKSFCETLEAYQLNPQKTTAADLPEDAISWFAENLKIFAPATERLYLTAASNLYEYLSAENLSQPNLARVRQLIRQRSRRPGLRLPQFPASDIDQLLEKIDQLKGKPCENVEEHLRNLRDRAFLLTLADTGLRVHEACALRRGDLDWTDYRAVVIGKGDQQAVVRFSERAMEALRDYLKARADLDGSTGRPLASLPLFTRHDKGAGKKKVKGMNTNTGRNIVTERVKEFLGADAAGTITPHSFRHYFVTRVLQATNNLRIAQLLARHKSIAVTQRYSHLTDSELDQGYWDAIGRKEKEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X737</accession>
    <name>A0A0P6X737_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_06560</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062162.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06560"/>
    <dbReference type="EnsemblBacteria" id="KPL78865">
        <property type="protein sequence ID" value="KPL78865"/>
        <property type="gene ID" value="ADN00_06560"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="14"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="171" mass="20005" checksum="8D84BC3BAB1056CB" modified="2016-01-20" version="1">MAKKTVAPAENDRIRLRLLAEEDLEQTLSWRNQDDIRKWFFFQDRIEPANHRAWFEKYQARDNDFVFIIEAKDLDGIPIGQIALYDIDWEQRRGEYGRLMIGEPAAKGKGYAQDATQLVLEVAAEQFGLKEVYLEVYTHNQAARRVYEKSGFIVTESGPEVTKMSYFTHHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7C0</accession>
    <name>A0A0P6X7C0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_08050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062475.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77829">
        <property type="protein sequence ID" value="KPL77829"/>
        <property type="gene ID" value="ADN00_08050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL77829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="72" mass="8083" checksum="45FA021F10E2A2B9" modified="2016-01-20" version="1">MEKQLLDKICEQIYRRFPEVNGKKPTVKSQPNEQVLLVFSAVAKTSDGHSIPRTVRVLVSSNGKVLKTTTSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7H0</accession>
    <name>A0A0P6X7H0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_18880</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70108">
        <property type="protein sequence ID" value="KPL70108"/>
        <property type="gene ID" value="ADN00_18880"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="107" mass="12483" checksum="8B42F6F0400DD830" modified="2016-01-20" version="1">MDVMKRVFRLRLPAISGLWMYEVGETPEDAIRQVEREFEGKFAFCGDGSEWEIEPCPMDDLSRVCKDYRHLHRKVNELSVALKSKNIVLESRNKTINTLVKKIDNVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7T1</accession>
    <name>A0A0P6X7T1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Sugar ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_04235</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061713.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04235"/>
    <dbReference type="EnsemblBacteria" id="KPL79085">
        <property type="protein sequence ID" value="KPL79085"/>
        <property type="gene ID" value="ADN00_04235"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.204"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025997">
        <property type="entry name" value="SBP_2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13407">
        <property type="entry name" value="Peripla_BP_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132904" evidence="2">
        <location>
            <begin position="22"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="domain" description="Peripla_BP_4" evidence="3">
        <location>
            <begin position="62"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL79085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="367" mass="39612" checksum="C6FD7741EE403406" modified="2016-01-20" version="1">MKKLLGLIMVLSMVLALAACAAPVEETAAPEAAAPAEQAAAPTEAPAAEEAAPAAETPKVMGIVMPNATHGFTGESIKHAEAAAKELAAQYGFEYKFLTAGEASEQNNHIDTLLNEQVDVVVLWPMNGDELRSAAQKVMDAGIPLVIYDRLITDFTPTVEFMGDNVKIGEMTGEYFNNYFADEIAAGETINILEFKGDLSTVPTQRTDGFLSTASEQFNIVQSFTTDWQRAKAMEQMETFLNTSTDEEISSIQAIFTHDDEVVLGVLDAIAAYNGAAELNIRLISGVGARRENIDTFAPVKEQYGIDQVTYAFSPALIRQAVELGAEILNGGSPSGLILGETVEVDNSNGEEFRNHPIYITRYSLED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7T3</accession>
    <name>A0A0P6X7T3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">LuxR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_17580</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000042">
        <property type="protein sequence ID" value="KPL71211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064360.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000042.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17580"/>
    <dbReference type="EnsemblBacteria" id="KPL71211">
        <property type="protein sequence ID" value="KPL71211"/>
        <property type="gene ID" value="ADN00_17580"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="6"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="151"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL71211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="218" mass="24084" checksum="B08151603C5047C7" modified="2016-01-20" version="1">MIKKIRILLVDDQSLFREGMKTLLSVQEDFDVVGEAANGEEALRLAARYQPDVVLMDVRMPVMDGIQATRRLQETLPECKVIVLTTFEDDDNVFEGLRAGAVGYLLKDVSSEKLYEALRAAARGEYFMLPSITAKVMAEFSRLSRPSYSGASELAAPLSAREMEILALLATGVSNKEIAAHLVIAEGTVKNHVTSILSKLEVKDRMQAVLRAKELNLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X860</accession>
    <name>A0A0P6X860_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10945</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76484.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063051.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10945"/>
    <dbReference type="EnsemblBacteria" id="KPL76484">
        <property type="protein sequence ID" value="KPL76484"/>
        <property type="gene ID" value="ADN00_10945"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.881"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="1">
        <location>
            <begin position="15"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76484.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="324" mass="36517" checksum="18E5FC2F5D8FEC35" modified="2016-01-20" version="1">MDYRNMGRTGLKVSPLCMGSMQFGWTADEDTSFSILNAAFRAGINFIDTANVYSRWVPGNPGGVSEEIIGNWMKKFKIPRGKLVIATKVRGPMGDGPNDQGLSRGHILREVEESLRRLQTDYIDLYQTHYFDEQTPIEETLSTLDDLVRQGKVRYVGCSNYPVWRLVQSFWTADRLRLGRYDTLQPHYNLVHRQEFELELEEVCLNFGLGVIPYSPLAGGFLTGKYRPNQTDVDSARAGGAARYFTERNWALLDKMEAMGVELGGRSISQVALAWLLTRPSVTSPIIGPRTLEQLEDNLGALAFELPPGMVEELDQASEWRNQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X8B6</accession>
    <name>A0A0P6X8B6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_07735</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78332">
        <property type="protein sequence ID" value="KPL78332"/>
        <property type="gene ID" value="ADN00_07735"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="70" mass="7681" checksum="4E247496AD4CA040" modified="2016-01-20" version="1">MGFYGHTFPILMESLTPQAGCWAGRKNGLCRIPLELLFPKKMKIIPGQAASLNLPQSASSQTLPLKGLRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X932</accession>
    <name>A0A0P6X932_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_12185</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063291.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12185"/>
    <dbReference type="EnsemblBacteria" id="KPL76094">
        <property type="protein sequence ID" value="KPL76094"/>
        <property type="gene ID" value="ADN00_12185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="219" mass="24155" checksum="EF95C5B62396379A" modified="2016-01-20" version="1">MQQDKWAIIWDMDGVIVQSAKLHYTALKQVFAARGYPYEWDVFISQFGRNNKSIVRDVIPTATPQEVDQMDSELISIFLSLVPGNVALLPGVLDWLQRFQAWGFAQGIASSSPIENINLITATTGIQSYFDIMNSGGELPPKPNPDIYLQVAQSVHVPPQRCVIIEDAPVGVQGAQRAGMRCIAVETNHPANRLQGATIIVPDLSHLTVEEFTSRVIAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X978</accession>
    <name>A0A0P6X978_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">UDP-N-acetylmuramyl-tripeptide synthetase</fullName>
            <ecNumber evidence="7">6.3.2.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">UDP-MurNAc-tripeptide synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">murE</name>
        <name evidence="12" type="ORF">ADN00_12415</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the addition of an amino acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="7 8">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="7">Carboxylation is probably crucial for Mg(2+) binding and, consequently, for the gamma-phosphate positioning of ATP.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the MurCDEF family. MurE subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.-" evidence="7"/>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12415"/>
    <dbReference type="EnsemblBacteria" id="KPL76176">
        <property type="protein sequence ID" value="KPL76176"/>
        <property type="gene ID" value="ADN00_12415"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016881">
        <property type="term" value="F:acid-amino acid ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00208">
        <property type="entry name" value="MurE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036565">
        <property type="entry name" value="Mur-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004101">
        <property type="entry name" value="Mur_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036615">
        <property type="entry name" value="Mur_ligase_C_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013221">
        <property type="entry name" value="Mur_ligase_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000713">
        <property type="entry name" value="Mur_ligase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035911">
        <property type="entry name" value="MurE/MurF_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005761">
        <property type="entry name" value="UDP-N-AcMur-Glu-dNH2Pim_ligase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01225">
        <property type="entry name" value="Mur_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02875">
        <property type="entry name" value="Mur_ligase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08245">
        <property type="entry name" value="Mur_ligase_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53244">
        <property type="entry name" value="SSF53244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53623">
        <property type="entry name" value="SSF53623"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63418">
        <property type="entry name" value="SSF63418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01085">
        <property type="entry name" value="murE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7 8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 7 8" id="KW-0132">Cell division</keyword>
    <keyword evidence="3 7 8" id="KW-0133">Cell shape</keyword>
    <keyword evidence="6 7 8" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0436">Ligase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 7 8" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Mur_ligase" evidence="9">
        <location>
            <begin position="16"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_M" evidence="11">
        <location>
            <begin position="101"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="domain" description="Mur_ligase_C" evidence="10">
        <location>
            <begin position="333"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="UDP-MurNAc-L-Ala-D-Glu binding" evidence="7">
        <location>
            <begin position="147"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="23"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="103"/>
            <end position="109"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="174"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="180"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>UDP-N-acetyl-alpha-D-muramoyl-L-alanyl-D-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:83900"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-carboxylysine" evidence="7">
        <location>
            <position position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF08245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KPL76176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="511" mass="55195" checksum="CE48A4ED483CE8E8" modified="2016-01-20" version="1">MPIEVLSLKEIPAVSITGVQQNSRKVTPGNLFVAQVGDMVDGHKYIPEAIKKGAAAIVGSEALEGKFDVPYIQVSDSRAASAYLSAAFFGFPARQLTVIGVTGTDGKTTTSNLIYNILLQAGYPTGIISTVNAVIGDEILDTGFHVTTPDAPEIQRLLSRMVTAGLRYVVLETTSHGLAQDRVTGCEFDVAVVTNITHEHLDYHGTYEAYRAAKGRLLDYLAETAPKKHGNPRVAVINRDDMSYEYLRQKPVENLVCYGQTSNQATIWSENICFDACGLHFDLVSDTFRLPIVSPLVGDYNVSNILAAAAAAIYGLGIDPPVAARGVAAVHGIPGRMERINLGQKFTALVDFAHTPNALRKALETARRLTKGRVIAVFGSAGLRDREKRHLMAEESARLADISIFTAEDPRTESLDDILAEMAAAAAKVGAEEGISFFRVPDRGDAIRFALQMAKDGDLVIACGKGHEQSMCFGTTEYAWDDRIAMRAALAEFLHQPGPQMPSLPTSRKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XA55</accession>
    <name>A0A0P6XA55_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_03380</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061554.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78953">
        <property type="protein sequence ID" value="KPL78953"/>
        <property type="gene ID" value="ADN00_03380"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="752" mass="85041" checksum="EFE1EB8F64722617" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAH5</accession>
    <name>A0A0P6XAH5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Single-stranded-DNA-specific exonuclease RecJ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_15105</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RecJ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063870.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15105"/>
    <dbReference type="EnsemblBacteria" id="KPL72161">
        <property type="protein sequence ID" value="KPL72161"/>
        <property type="gene ID" value="ADN00_15105"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.723"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008409">
        <property type="term" value="F:5'-3' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001667">
        <property type="entry name" value="DDH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038763">
        <property type="entry name" value="DHH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003156">
        <property type="entry name" value="DHHA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004610">
        <property type="entry name" value="RecJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041122">
        <property type="entry name" value="RecJ_OB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01368">
        <property type="entry name" value="DHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02272">
        <property type="entry name" value="DHHA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17768">
        <property type="entry name" value="RecJ_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64182">
        <property type="entry name" value="SSF64182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00644">
        <property type="entry name" value="recJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHH" evidence="6">
        <location>
            <begin position="81"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="domain" description="DHHA1" evidence="7">
        <location>
            <begin position="318"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="domain" description="RecJ_OB" evidence="8">
        <location>
            <begin position="455"/>
            <end position="556"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF17768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL72161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="771" mass="84712" checksum="486FDD0CC236B61F" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAM7</accession>
    <name>A0A0P6XAM7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_02145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000009">
        <property type="protein sequence ID" value="KPL79807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02145"/>
    <dbReference type="EnsemblBacteria" id="KPL79807">
        <property type="protein sequence ID" value="KPL79807"/>
        <property type="gene ID" value="ADN00_02145"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2751"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010945">
        <property type="term" value="F:CoA pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03426">
        <property type="entry name" value="CoAse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045121">
        <property type="entry name" value="CoAse"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12992">
        <property type="entry name" value="PTHR12992"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="22"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="184" mass="21028" checksum="74EA663539AA12D4" modified="2016-01-20" version="1">MDAWVQQHLPVVGVSTRTAQDLRRAAVLIPLLQADGQWNLLFTRRTDTVLDHKGQVSFPGGAREAFDLSDEETALREAQEEIGLDPACVKVLGKLEPFETISRYEVIPIVARLDWPVRLTLSPQEVNRVFTIPVGWLGDCKNWTEVAYNHHQVIQYERYDGELLWGITASITHQFLRKMDWMGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAU6</accession>
    <name>A0A0P6XAU6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N6_N4_Mtase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_15560</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72299">
        <property type="protein sequence ID" value="KPL72299"/>
        <property type="gene ID" value="ADN00_15560"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006306">
        <property type="term" value="P:DNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002941">
        <property type="entry name" value="DNA_methylase_N4/N6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001091">
        <property type="entry name" value="RM_Methyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01555">
        <property type="entry name" value="N6_N4_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00508">
        <property type="entry name" value="S21N4MTFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N6_N4_Mtase" evidence="3">
        <location>
            <begin position="14"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL72299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="87" mass="9673" checksum="87F7BE55847BD293" modified="2016-01-20" version="1">MTGVYDDRLVLPPIHPYEKPLSLIERLIRIYTNPGAVVLDPFCGSGTTLVACMNLKRKAIGIEKDHSKYLLAQDRLLGLLPGRLKGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XB28</accession>
    <name>A0A0P6XB28_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_02740</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000013">
        <property type="protein sequence ID" value="KPL79374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061429.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000013.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79374">
        <property type="protein sequence ID" value="KPL79374"/>
        <property type="gene ID" value="ADN00_02740"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="188"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="229"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="262"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="287"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="10"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="158"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="324" mass="35042" checksum="B67C09D5741CFA9B" modified="2016-01-20" version="1">MNQPSTNLARGYPIALLSTVFLSTTAIFIRYLITTYQPPALLLAFWRAALAAVVLITVLALVKPALLRVTRAQLGYLVLYGLLLCAFNSLWTLSVAINGAAVSNVLVYCSTAFTALLGWWLLKERLTPLRLLVVVICFSGCVFVSQAYTPQVWSANLSGILAGLLSGLGYAAYSLMGRSASQRGLNPWSTLAYTFFFAAFFLGLLNLLPFPIPATLDDPARFLWFGSAWQGWGLLFLLAAVPTLMGYGLYMVSLSFLPSSTANLIATVEPVLTIFIAFFFLGERLSLDQIFGSALIIGGVVLLRVFEGRRAPSPAAVEPASLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBC6</accession>
    <name>A0A0P6XBC6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">PMT_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ADN00_15995</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064043.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15995"/>
    <dbReference type="EnsemblBacteria" id="KPL72000">
        <property type="protein sequence ID" value="KPL72000"/>
        <property type="gene ID" value="ADN00_15995"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038731">
        <property type="entry name" value="RgtA/B/C-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13231">
        <property type="entry name" value="PMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="29"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="57"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="106"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="186"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="212"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="240"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="282"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="307"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="429"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="455"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="510"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="domain" description="PMT_2" evidence="9">
        <location>
            <begin position="192"/>
            <end position="315"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL72000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="651" mass="73022" checksum="2B8051D139A1F564" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBJ1</accession>
    <name>A0A0P6XBJ1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HTH tetR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_16495</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064140.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72073">
        <property type="protein sequence ID" value="KPL72073"/>
        <property type="gene ID" value="ADN00_16495"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041490">
        <property type="entry name" value="KstR2_TetR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17932">
        <property type="entry name" value="TetR_C_24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="5">
        <location>
            <begin position="13"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="4">
        <location>
            <begin position="36"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL72073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="197" mass="22467" checksum="243122E6266F8ACC" modified="2016-01-20" version="1">MPKGIPLTEEEQARRRKEIAQVAIQLILKKGFNETSMREIAEAAGTGKSTLYDYFATKDDILISYFEDEIQTITQSAQEIDQLPITAFEKLRRVMQKHLAYLLENKQLYMRLTIEAQRLGLESQQRMAASRHAYQDLICRMIEKGIQEGSFRPIDPVLAMRIILGTMTPVAFTTRPTGTPEEMLDVSMDIILKGIQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBV1</accession>
    <name>A0A0P6XBV1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_15680</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063973.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15680"/>
    <dbReference type="EnsemblBacteria" id="KPL72256">
        <property type="protein sequence ID" value="KPL72256"/>
        <property type="gene ID" value="ADN00_15680"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.841"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008841">
        <property type="entry name" value="Siphovirus-type_tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05709">
        <property type="entry name" value="Sipho_tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="287" mass="31370" checksum="5981114F94E968CA" modified="2016-01-20" version="1">MSYNVAFTNANGISINLNDRVNTYSMVGISNDLMPGFEFQESSSPLIHGSIVNAARISQRDYLLPIMVIDADRGSVMSRIRTMLSILDPRKGDGQLRITNEGVTRVLNCRYRSGLSSDGTGPDQFTNWIRGVIDFYASDPYFYAASPITLQVSGDWSPYNFFPILPVRFAASSSTVTATLTNSGDVEAWPVITITGPGTHFHVTNHTSGKFIVVDTTLLTGESLIIDTRPRTRSIRDGDGVNRFAYLTPASSLFPMKQGNNQVEVEIVGGNGNTSVTVMYTPAYLTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XCF2</accession>
    <name>A0A0P6XCF2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_07985</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77910.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77910">
        <property type="protein sequence ID" value="KPL77910"/>
        <property type="gene ID" value="ADN00_07985"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002830">
        <property type="entry name" value="UbiD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30108">
        <property type="entry name" value="PTHR30108"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01977">
        <property type="entry name" value="UbiD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00148">
        <property type="entry name" value="TIGR00148"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="362"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="375"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77910.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="421" mass="46633" checksum="E7D2A993AD8CA8D9" modified="2016-01-20" version="1">MLEVSAPISKTYQIAGVLKQIEPRPAIFSHVIESKFPVMGNLFCSKASFASYFGVPVHQIIPLLAGAIENRSACERVSAAPCQEVVNLSPDLDELPILRHCEKDGGNYISSGVFVTRHPQYGQNLDFHRCMQLSKTEMSVRVVKSRHFDAFLEDLRDLDVAICIGNAPNVLAAAATSVELGVDELEIANALEPLQVVKAKTVDVWVPAECEFVIEGTVHLDRLREEGPFVDLTETYDIVRQQPVLEVKAITHRRDAIWHALLPGALEHKLLMGMPREPTIFRKVNQVARCLDVNISPGGTSWLHAIVQIDKQHEDDGRKAIEAAFAGHTSCKHVFVVDSDIDIYNPLEVEWAMATRFQGDRDLIIKPPSPGSSLDPSAEPGTKNTTRVGFDLTKPLETQGKSFDRAAFPQVDLNQFVKDTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XCY0</accession>
    <name>A0A0P6XCY0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Glyco_trans_2-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_01490</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01490"/>
    <dbReference type="EnsemblBacteria" id="KPL80544">
        <property type="protein sequence ID" value="KPL80544"/>
        <property type="gene ID" value="ADN00_01490"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="205"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="258"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_trans_2-like" evidence="2">
        <location>
            <begin position="18"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL80544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="314" mass="34917" checksum="369DA1E354AF9E6E" modified="2016-01-20" version="1">MFNEEAAAALFHQQLSEAIAGLPYTFNILYVNDGSRDQTQAVLEQLVQADARVRVIELSRNFGHQAALTAGLDRACGDYTITLDGDGQHPPALISEMLALAEQGYDIVLTQRVEEQGLTPFKRLTSALFYRVINRLGETQILPGGADFRLMSRVVVEKLRGMREYHRFLRGMVAWMGFKTIILPFTPPQRLAGASKYSLRKMLRLGMNAIFSFSLMPLYAAVSIGALFLVLALIEAVYVLSFWVTGNTAQLAPGWSSLMFMLLIIGGSLMVTLGLIGIYIGYIFQEVKQRPIYLIRKAISQKPPHDENPLDPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDG6</accession>
    <name>A0A0P6XDG6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Cell division protein FtsA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ftsA</name>
        <name evidence="8" type="ORF">ADN00_07415</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Cell division protein that is involved in the assembly of the Z ring. May serve as a membrane anchor for the Z ring.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Self-interacts. Interacts with FtsZ.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
            <orientation evidence="5">Cytoplasmic side</orientation>
        </subcellularLocation>
        <text evidence="5">Localizes to the Z ring in an FtsZ-dependent manner. Targeted to the membrane through a conserved C-terminal amphipathic helix.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the FtsA/MreB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78285.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062347.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07415"/>
    <dbReference type="EnsemblBacteria" id="KPL78285">
        <property type="protein sequence ID" value="KPL78285"/>
        <property type="gene ID" value="ADN00_07415"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3306"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009898">
        <property type="term" value="C:cytoplasmic side of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02033">
        <property type="entry name" value="FtsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020823">
        <property type="entry name" value="Cell_div_FtsA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003494">
        <property type="entry name" value="SHS2_FtsA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02491">
        <property type="entry name" value="SHS2_FTSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003101">
        <property type="entry name" value="FtsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00842">
        <property type="entry name" value="FtsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01174">
        <property type="entry name" value="ftsA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 6" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2 5 6" id="KW-0132">Cell division</keyword>
    <keyword evidence="1 5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FtsA" evidence="7">
        <location>
            <begin position="6"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR003101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL78285.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="409" mass="44001" checksum="D0FF1744AA8DCD36" modified="2016-01-20" version="1">MDESIVVGIDIGTTKVCTLVARIEGERNLRILGVGIAPSQGIRKGNIIDLAAASQAIARSVEKAQRTSGLEITSALVSLAGSHVSSVNSRGVVGISGRVIDQYDVDRALESAQAVAIPHNREIIHVIQRGFTVDGQDGIRMPVGMHGYRLEVEAHIITAAAATVENLRQCVQAAGVQVSQFVLNPLASAEVVLTETERQMGCVVVDIGGGTTDMAIYIDGDVWHTMVIAIGGNLVTSDIAQGLRLPISQAEEVKKEHAFAVESAISADDVFTTRPFGEDQPIQFSRKDLAMITEARLEEIFTFVMQEIKRSGYDGLLPAGMILTGGSSLIPGIKDLASRVMNMPTRVARPENLIGLVDQLNSPAYSTSVGLLYWAMFLNETAPKTHRKPGPQINVNWDTIKNIFKNLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDM3</accession>
    <name>A0A0P6XDM3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FMN_red domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_07665</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062391.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07665"/>
    <dbReference type="EnsemblBacteria" id="KPL78321">
        <property type="protein sequence ID" value="KPL78321"/>
        <property type="gene ID" value="ADN00_07665"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FMN_red" evidence="1">
        <location>
            <begin position="6"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="197" mass="20898" checksum="057635940E865C8E" modified="2016-01-20" version="1">MNEQVRILGIGGTLAEKSTSLASLKKALSAAEKAGAVVELLDLRELDLPMFVPGKPLEAYGENVKRLVESARNADAMIWSTAAYNGSMAGSFKNAMDFLVFLKQGGQSFLENRVVGLIASSAGDQASINTIRAMTDVAHSLRAVVSPLSVPLHFAARKVDVEMGAMEEAAATRLELLGSVVTDLAVRMKGVAYPTMN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDT2</accession>
    <name>A0A0P6XDT2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">ABC_transp_aux domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_00595</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00595"/>
    <dbReference type="EnsemblBacteria" id="KPL81065">
        <property type="protein sequence ID" value="KPL81065"/>
        <property type="gene ID" value="ADN00_00595"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019196">
        <property type="entry name" value="ABC_transp_unknown"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09822">
        <property type="entry name" value="ABC_transp_aux"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="425"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="domain" description="ABC_transp_aux" evidence="2">
        <location>
            <begin position="37"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL81065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="455" mass="50307" checksum="CBF8689CD4DC1635" modified="2016-01-20" version="1">MKKSNQSHWVNLLLTVVLFAGIVGVSNLISVQLDWQLDLTQDKLNTLSDSTLQVIQSLPHPVKASAFYSKNYPTTTVIALLENFSRNSQGKFSYELIDYQRNPLAAREMDVVQDATIVVTMQDRRELVRFGSEQELLASILRLLDPSERSVYFLTGHGEYSLETSGKVTGYAALRKTLQAKNYIVRELSLLDAAKIPTDAQAIVIAGYQSALTTREVDLIANYLNNGGSLVLLLEPPSLTQIQDGQDPVVEYLDKEWGITAGSNMIIDPNADPPLIAITNAYKDHPIVNVLNDQRLTTIFPTARSIEIARVPETISHSVLAVTSKSAWAETNMDSITNSTAIPDVGVDPQGPITLGIAAQEFNADGRIVVIGDADFANDEYFDRFGNGDLMVNAISWAVKQEDRLNLNPKNQTVRIMVTPTRTSMVMLFIGSVLLIPGLIILFGFINWNRRKRKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XEX4</accession>
    <name>A0A0P6XEX4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_14230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000034">
        <property type="protein sequence ID" value="KPL73725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063696.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000034.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL73725">
        <property type="protein sequence ID" value="KPL73725"/>
        <property type="gene ID" value="ADN00_14230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL73725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="90" mass="10217" checksum="B420BFB53E12F5E7" modified="2016-01-20" version="1">MDYINDPGWDDEPLYDDQSNDYPPGWDNQPPYHPPSKAFDNNPTTRKPSAPPPQSSPGCLASLFGFALIDRIMFPSDEEGFDDFLDDLFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XFX8</accession>
    <name>A0A0P6XFX8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_14245</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000034">
        <property type="protein sequence ID" value="KPL73728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063699.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000034.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL73728">
        <property type="protein sequence ID" value="KPL73728"/>
        <property type="gene ID" value="ADN00_14245"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1369"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015093">
        <property type="entry name" value="DUF1887"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09002">
        <property type="entry name" value="DUF1887"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL73728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="303" mass="33898" checksum="D4E52DE08BDE23FE" modified="2016-01-20" version="1">MILLSLIGEQPIPNLLPLWQSGAVYTGTRFAVTQQTMRVAQSLREALARDAALKHLAVLDPLLLDAYDIDGDRRALVQAIQTLQERGEEVCVNLTGGTKLMSLAALQAAQDTLAPMLYVSTQSGEIIHLDLDGSQARREPIRVRVSVSQYLGAHGFETSLNPNFHLPQLRSFAPPKEGDPLENQVERLARDSGYFDDVQRGLFIRKRAKKQESRNELDLLVTRNGRLAVCSCKSGVKITKEMIYELDSIFSREDTGIYCAKVLVCAQEELPQAIRDRARNQNVHLVYGEHIQQIADVLLRVLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XI56</accession>
    <name>A0A0P6XI56_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Macro domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13165</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000030">
        <property type="protein sequence ID" value="KPL75179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063484.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000030.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13165"/>
    <dbReference type="EnsemblBacteria" id="KPL75179">
        <property type="protein sequence ID" value="KPL75179"/>
        <property type="gene ID" value="ADN00_13165"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.220.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002589">
        <property type="entry name" value="Macro_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043472">
        <property type="entry name" value="Macro_dom-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01661">
        <property type="entry name" value="Macro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00506">
        <property type="entry name" value="A1pp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52949">
        <property type="entry name" value="SSF52949"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51154">
        <property type="entry name" value="MACRO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Macro" evidence="1">
        <location>
            <begin position="3"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL75179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="189" mass="20166" checksum="50E3BCF475A092C7" modified="2016-01-20" version="1">MSQCIRSTNLSPQASLEICQGDITLEAVDAVVNAANAHLIHGGGVAAAIARRAGLPLDKESREWVQQHGPVTHTAPALTSAGAMPARYVIHAVGPIWGEGSEEPRLAETIHAVLALASQNGFASLAFPAISTGIYGFPKQLAAPIFFNTIQSYFTAEPESSIKLVRIVLYDQATLDAFLGEFDRWTANR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XK36</accession>
    <name>A0A0P6XK36_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 4">Imidazolonepropionase</fullName>
            <ecNumber evidence="1 4">3.5.2.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Imidazolone-5-propionate hydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">hutI</name>
        <name evidence="6" type="ORF">ADN00_01390</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the hydrolytic cleavage of the carbon-nitrogen bond in imidazolone-5-propanoate to yield N-formimidoyl-L-glutamate. It is the third step in the universal histidine degradation pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>4-imidazolone-5-propanoate + H2O = N-formimidoyl-L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:23660"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58928"/>
            <dbReference type="ChEBI" id="CHEBI:77893"/>
            <dbReference type="EC" id="3.5.2.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="4">
            <name>Fe(3+)</name>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
        </cofactor>
        <text evidence="4">Binds 1 zinc or iron ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">Amino-acid degradation; L-histidine degradation into L-glutamate; N-formimidoyl-L-glutamate from L-histidine: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the metallo-dependent hydrolases superfamily. HutI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.2.7" evidence="1 4"/>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061172.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01390"/>
    <dbReference type="EnsemblBacteria" id="KPL80528">
        <property type="protein sequence ID" value="KPL80528"/>
        <property type="gene ID" value="ADN00_01390"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1030"/>
    <dbReference type="UniPathway" id="UPA00379">
        <property type="reaction ID" value="UER00551"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050480">
        <property type="term" value="F:imidazolonepropionase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019556">
        <property type="term" value="P:histidine catabolic process to glutamate and formamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019557">
        <property type="term" value="P:histidine catabolic process to glutamate and formate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00372">
        <property type="entry name" value="HutI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005920">
        <property type="entry name" value="HutI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42752">
        <property type="entry name" value="PTHR42752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01224">
        <property type="entry name" value="hutI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0369">Histidine metabolism</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 4" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="5">
        <location>
            <begin position="65"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="74"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="76"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>4-imidazolone-5-propanoate</name>
            <dbReference type="ChEBI" id="CHEBI:77893"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="146"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>4-imidazolone-5-propanoate</name>
            <dbReference type="ChEBI" id="CHEBI:77893"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="251"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>4-imidazolone-5-propanoate</name>
            <dbReference type="ChEBI" id="CHEBI:77893"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="326"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="328"/>
        </location>
        <ligand>
            <name>N-formimidoyl-L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:58928"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="330"/>
        </location>
        <ligand>
            <name>N-formimidoyl-L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:58928"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL80528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="420" mass="44793" checksum="207A327916047770" modified="2016-01-20" version="1">MLIHSASQLVTLAGGPRRGADMNRLEIIADGAMLMEAGRIAAVGESAALLARYPRAERLDARGRVVMPGLVDPHTHLVWAGDRAAEFEMRLQGKSYMEIMAAGGGIAATVRATRQASRDELLAQTRQRARRMLAHGTTTVEAKTGYGLDLASELAQLEVLLALDEEGPLEIAPTFMGAHAVAPEFNGDAQAFTDHICAVMLPAVRDWWQQNAAARALPFVDVFSEKGVFDLEQTRQILLAARALGFPLKLHVDEFENIGAASLAAELGAVSADHLVKTSPRDIEALARSDTVAVSLPCTPFGLGQHEYTPAQQIIAAGGMLALATDLNPGPAWCENMQFVLALACRAMRLTPAEALCAATINAAAAVRRDGLVGSLEAGKQADALVLQSGDFRDLAYRFGVNQVQTVIKKGEVVYNAPII</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKS1</accession>
    <name>A0A0P6XKS1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_15285</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063905.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15285"/>
    <dbReference type="EnsemblBacteria" id="KPL72193">
        <property type="protein sequence ID" value="KPL72193"/>
        <property type="gene ID" value="ADN00_15285"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.759"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03408">
        <property type="entry name" value="SPFH_like_u1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041657">
        <property type="entry name" value="HTH_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010093">
        <property type="entry name" value="SinI_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033880">
        <property type="entry name" value="SPFH_YdjI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13421">
        <property type="entry name" value="Band_7_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12728">
        <property type="entry name" value="HTH_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01764">
        <property type="entry name" value="excise"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Band_7_1" evidence="2">
        <location>
            <begin position="19"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="domain" description="HTH_17" evidence="1">
        <location>
            <begin position="301"/>
            <end position="348"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL72193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="349" mass="37111" checksum="2D772057AACC8579" modified="2016-01-20" version="1">MARIFDVVEYPNEMKDEIVHRFPETGVADLRIGSQVIVRESQQVVFFRDGKALDIFGPGRHTIVTANVPKLIDFIGKAFNDRTPFTAEVYYVSMKEFADHKWGTPQPIIVRNPGMGLGVALLQGFGTYSFQVADAQQFITQVVGAQGIYRMSDIENRLRTMLLSKLQDLLGETAAAKSVVDLIGLTEELGAGVRAKAQDDFAAIGLLLKSFYIGNLKPSSKSAEELRAMGMLDMQTYTQLQAADAMRDAAQNPSGGAGLTAGIGAGMGIGNVLGQSLSGMTNAAAGAAAASQNGTPAMPDVMTPAEAAGIMRVSEEDVIAAINAGDLKARKIGSAFRISKAALEDFLKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XL47</accession>
    <name>A0A0P6XL47_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Zinc permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_10090</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76934.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062877.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76934">
        <property type="protein sequence ID" value="KPL76934"/>
        <property type="gene ID" value="ADN00_10090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2481"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046873">
        <property type="term" value="F:metal ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003689">
        <property type="entry name" value="ZIP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02535">
        <property type="entry name" value="Zip"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="70"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="128"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="165"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="224"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL76934.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="244" mass="26197" checksum="BE7ABEF4DE5CE7D4" modified="2016-01-20" version="1">MFLNTFGAVTLASFLACLVTSIGIYTISAHEQWGNRNVIYFMSFAAGVLISVSFIHIIPKSIEMTSQAPIYLLVGFMGLYIINRFVSRFVCRETDCRNISIGVIPMVGIGLHSFIDGVIYSVTFNVSIFTGVLAAIGMVLHEFPEGVVTFLLLEQAGFPRKKAAVMAFLAAALTTPLGTLISFPVINQINQRSLGNLLGLSAGALVYVGATHLLPAVENEKKQHSMISLGAGILIAILIVISKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XLX6</accession>
    <name>A0A0P6XLX6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062722.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77318">
        <property type="protein sequence ID" value="KPL77318"/>
        <property type="gene ID" value="ADN00_09330"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="SSF54106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LysM" evidence="1">
        <location>
            <begin position="191"/>
            <end position="235"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="293" mass="31243" checksum="BD6AC15BACD6CEDC" modified="2016-01-20" version="1">MGKTLIEPAKPIPTADTPALAMDTLTSFNVCPYLGLKNDPLTHSLTAEVPNYCYHCQPPRRVPSAQLRLCFEGGSSTCTFAATRPPRKTPSLRRLLRRFALPAGGLVILSGAAAALLNSTPRADQPLPPQPPAPTVQSALMAAPAEPSTPFNPLPTYTVIEPTPTFTLLPTEPPTPGPLAETPFGPGSKLLVHVVLEGETLESLAERHNTSVDVLLALNPRGGRASLWTGEPLVIAANLTDPALAQPLRAFWVESALPLADLARDLGVSADSLRVWNDLQGDWVEGNRWVVGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XLY8</accession>
    <name>A0A0P6XLY8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sugar ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_09455</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062744.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77336">
        <property type="protein sequence ID" value="KPL77336"/>
        <property type="gene ID" value="ADN00_09455"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="71"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="154"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="200"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="271"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="68"/>
            <end position="287"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL77336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="294" mass="33630" checksum="C18F784C56F9ED3E" modified="2016-01-20" version="1">MKYWLRKTYKHYLMLLPFFIFFSIFFLYPILKGLNTSFYKWDSVNPAVFVGFQNYIHLLKSRDFIISFTNILKYVSITVPLGITVAFALALFVNSLTGPVANFFRSAYFVPTMMPLFLAASVWRWMYAPEVGIINTAIQALGLESVNWLKDPSVMIYALIVVDVWRSAGWNMVILLAGLKNIPNDYYDAAKVDGANQWQELIYITIPLLESVLFFVIAQGFIFALQVFDAPWLLTLSTTQGYGGRLKALLFPVMDMFGRAFGVYKFGEASAYGFLLTVLIMMITAILFLLRRKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XM33</accession>
    <name>A0A0P6XM33_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF58 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_18040</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL69973.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064439.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18040"/>
    <dbReference type="EnsemblBacteria" id="KPL69973">
        <property type="protein sequence ID" value="KPL69973"/>
        <property type="gene ID" value="ADN00_18040"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002881">
        <property type="entry name" value="DUF58"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01882">
        <property type="entry name" value="DUF58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="DUF58" evidence="2">
        <location>
            <begin position="202"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL69973.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="402" mass="44857" checksum="37F717F9E5A56484" modified="2016-01-20" version="1">MSLHRSWPIFVTLFLAGAMLRQEWLVIFSGAFLLILLAASLSRRFAFRGVTYRRHWHYRRGFPGEETTLRVEIENRKLLPLTWLRASDQWPLDAAPVDKNALSPSNIAGQGQLVNALSLKPDEKVTRTYPLRFRKRGVYTVGPVDLETSDIFGLAPLEKRLSYPETLTVFPQILPLNALRLPADDPFGERAAPRRLFEDPTQPMGVRPYQPEDDFRHVHWPATARSGAVQVKVYQPVTSHVLTVCLNVSTSYHAWLGTNQHLLEALINVAASACYHAFNSGCSVGLVSNGCLSHADRPFQIAPGRSSNQLATLLQSLAAVTVYTTAPFEDFLIRSLPKIPYGSTLMIVTALLPDSLVESLMRLKKYRPHTTLISLAESAPPTLPGIQTIHLPYSEDLLAHAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XMB7</accession>
    <name>A0A0P6XMB7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_00085</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL80991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00085"/>
    <dbReference type="EnsemblBacteria" id="KPL80991">
        <property type="protein sequence ID" value="KPL80991"/>
        <property type="gene ID" value="ADN00_00085"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05729">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="domain" description="NACHT" evidence="2">
        <location>
            <begin position="141"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL80991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="828" mass="92733" checksum="AE3647C829D57484" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XNI6</accession>
    <name>A0A0P6XNI6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UvrABC system protein C</fullName>
            <shortName evidence="6">Protein UvrC</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Excinuclease ABC subunit C</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">uvrC</name>
        <name evidence="10" type="ORF">ADN00_14520</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Interacts with UvrB in an incision complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the UvrC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000035">
        <property type="protein sequence ID" value="KPL73601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063753.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000035.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14520"/>
    <dbReference type="EnsemblBacteria" id="KPL73601">
        <property type="protein sequence ID" value="KPL73601"/>
        <property type="gene ID" value="ADN00_14520"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2070"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009380">
        <property type="term" value="C:excinuclease repair complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009381">
        <property type="term" value="F:excinuclease ABC activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00203">
        <property type="entry name" value="UvrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041663">
        <property type="entry name" value="DisA/LigA_HHH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035901">
        <property type="entry name" value="GIY-YIG_endonuc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003583">
        <property type="entry name" value="Hlx-hairpin-Hlx_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001943">
        <property type="entry name" value="UVR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036876">
        <property type="entry name" value="UVR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004791">
        <property type="entry name" value="UvrC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001162">
        <property type="entry name" value="UvrC_RNase_H_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038476">
        <property type="entry name" value="UvrC_RNase_H_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01541">
        <property type="entry name" value="GIY-YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12826">
        <property type="entry name" value="HHH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08459">
        <property type="entry name" value="UvrC_HhH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00465">
        <property type="entry name" value="GIYc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00278">
        <property type="entry name" value="HhH1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46600">
        <property type="entry name" value="SSF46600"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82771">
        <property type="entry name" value="SSF82771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00194">
        <property type="entry name" value="uvrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50151">
        <property type="entry name" value="UVR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50165">
        <property type="entry name" value="UVRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3 6" id="KW-0228">DNA excision</keyword>
    <keyword evidence="5 6" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4 6" id="KW-0267">Excision nuclease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="GIY-YIG" evidence="8">
        <location>
            <begin position="16"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="UVR" evidence="7">
        <location>
            <begin position="205"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="UVRC" evidence="9">
        <location>
            <begin position="256"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL73601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="620" mass="69920" checksum="F2C2F0A84542BC56" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XNQ9</accession>
    <name>A0A0P6XNQ9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">30S ribosomal protein S7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpsG</name>
        <name evidence="10" type="ORF">ADN00_06870</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Part of the 30S ribosomal subunit. Contacts proteins S9 and S11.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the universal ribosomal protein uS7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062244.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06870"/>
    <dbReference type="EnsemblBacteria" id="KPL78205">
        <property type="protein sequence ID" value="KPL78205"/>
        <property type="gene ID" value="ADN00_06870"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3190"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.455.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00480_B">
        <property type="entry name" value="Ribosomal_S7_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000235">
        <property type="entry name" value="Ribosomal_S5/S7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005717">
        <property type="entry name" value="Ribosomal_S7_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020606">
        <property type="entry name" value="Ribosomal_S7_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023798">
        <property type="entry name" value="Ribosomal_S7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036823">
        <property type="entry name" value="Ribosomal_S7_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11205">
        <property type="entry name" value="PTHR11205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00177">
        <property type="entry name" value="Ribosomal_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002122">
        <property type="entry name" value="RPS7p_RPS7a_RPS5e_RPS7o"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47973">
        <property type="entry name" value="SSF47973"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01029">
        <property type="entry name" value="rpsG_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00052">
        <property type="entry name" value="RIBOSOMAL_S7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 6 8" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="6" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_S7" evidence="9">
        <location>
            <begin position="2"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003619"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003620"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00177"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL78205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="155" mass="17540" checksum="51C7D295705AF7AD" modified="2016-01-20" version="1">MRRTKPEKREIAPDVRFNSVTVSFLINRIMKNGKKSGATSMMYEAMDIVKAKTGKEPMEVLETALKNVGPIMEVRPRRVGGATYQVPMEVPSHRRMTLAMRWILDASRARSGKSFAEKLAAEILDAASNQGSAIRKREETHKMAEANRAFSHYRM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XNT6</accession>
    <name>A0A0P6XNT6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Thymidine phosphorylase</fullName>
            <ecNumber evidence="6">2.4.2.4</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">deoA</name>
        <name evidence="6" type="ORF">ADN00_07140</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.4" evidence="6"/>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78241.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062294.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07140"/>
    <dbReference type="EnsemblBacteria" id="KPL78241">
        <property type="protein sequence ID" value="KPL78241"/>
        <property type="gene ID" value="ADN00_07140"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3246"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004645">
        <property type="term" value="F:1,4-alpha-oligoglucan phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016154">
        <property type="term" value="F:pyrimidine-nucleoside phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009032">
        <property type="term" value="F:thymidine phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006206">
        <property type="term" value="P:pyrimidine nucleobase metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006213">
        <property type="term" value="P:pyrimidine nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1030.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1170.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000312">
        <property type="entry name" value="Glycosyl_Trfase_fam3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017459">
        <property type="entry name" value="Glycosyl_Trfase_fam3_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036320">
        <property type="entry name" value="Glycosyl_Trfase_fam3_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035902">
        <property type="entry name" value="Nuc_phospho_transferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036566">
        <property type="entry name" value="PYNP-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013102">
        <property type="entry name" value="PYNP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018090">
        <property type="entry name" value="Pyrmidine_PPas_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000053">
        <property type="entry name" value="Thymidine/pyrmidine_PPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10515">
        <property type="entry name" value="PTHR10515"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02885">
        <property type="entry name" value="Glycos_trans_3N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00591">
        <property type="entry name" value="Glycos_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07831">
        <property type="entry name" value="PYNP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000478">
        <property type="entry name" value="TP_PyNP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00941">
        <property type="entry name" value="PYNP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47648">
        <property type="entry name" value="SSF47648"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52418">
        <property type="entry name" value="SSF52418"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54680">
        <property type="entry name" value="SSF54680"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02644">
        <property type="entry name" value="Y_phosphoryl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PYNP_C" evidence="5">
        <location>
            <begin position="345"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL78241.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="434" mass="46179" checksum="2693BF9CA92826BA" modified="2016-01-20" version="1">MRAVDIIIKKRDHEVLTREEIDFFVSGFSKNEIPDYQVAAWAMAVLLNGMTDQETTDLTLAMVRSGEMLDFSHVVDTVVDKHSTGGVGDKTTLVVAPIVAACGLPVGKMSGRGLGFSGGTLDKMESIPGYRVDLTRDEFVRQLKEVGIVLSGQSADLAPADGKLYALRDVTGTVPSMPLIASSVMSKKIAAGANAILLDVKTGVGAFMETEEDARKLAELMVAIGKLSGRKVIGMISDMNQPLGFAVGNALEVKEAIDALHGEGPDDFMEHCLVVSSYMLLMAKRAETLDDAREMCERSIADGSALEMFKKLVAAQGGDVSYVDHPEKLPQASLVETITASQDGFVQQINAREIGETSVELGAGRARKGDPVDHAVGIVVHCKVGDAVKQGEELASVHANDEAKLSAAVERVKGAFVVGSEACEPLPLFYGVIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XNZ5</accession>
    <name>A0A0P6XNZ5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_07685</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062395.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78324">
        <property type="protein sequence ID" value="KPL78324"/>
        <property type="gene ID" value="ADN00_07685"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="413" mass="44855" checksum="BF4D47ED32EBB63C" modified="2016-01-20" version="1">MQEKENQTAQPRSFQSLLPTLGIGFLLTIVLISLGLSIWMTAPSYLAKVRGTPTPSPLPPTATLLPTTTATITPLPSDTPLPSATPYPASAWKVEDLSQVNPPIPGPALEAIVLNNDTSVTVDPPFSSILWTNSADLGLGIDFEDDFYATYSAGSATWALDKPLAPGYYQIYVLDTAYSSGGVLDYVVSNSTGQIGPISGRTRVLFSSSFTTPPQTNSTWESIGIYKLDQPDLLTISTAWEDRNEYTIVAIDRVLITRLPDSTGQLLSELPHSGLNYVYDDLSANLTVRDPLFEREGRSWGDRYQSILNPEYDVTLTWKSDNVIPVANYEIFAYLPATKGSVEGEFHFLVNGDEFLKDPETISLNTDTAGWVSLGTLEIPEVYGVAVNFEMSMKVPAGSVGEVPLDAVGLAQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XP21</accession>
    <name>A0A0P6XP21_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_07590</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07590"/>
    <dbReference type="EnsemblBacteria" id="KPL78360">
        <property type="protein sequence ID" value="KPL78360"/>
        <property type="gene ID" value="ADN00_07590"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="95"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="123"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="233"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="272"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="315"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="360"/>
            <end position="378"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL78360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="401" mass="42466" checksum="892CC313182BB1F7" modified="2016-01-20" version="1">MEEVAEKKSFWQVVLIPLLAVITGLLIGGIFIVLTTESVYASFGESFGAGMKAAWETVKGAYVALFTGSIGDPARIIAALQSGDAMDIRRAFNPFLESLVASTPYIFAGLAVALGFRAGVFNIGAEGQIFVGALAGTFIGYSIKGLPAVIHMPLTFLAGAAGGALWGYIPGWLKAKTGGHEVINTIMMNYIAFRLSDWLLTGPMKRPESFNPVTPNIEPSAVFPKFFADPIRFHLGFFVALTVAYLVYWFLFKTTWGFNLRTVGANPDAAKYSGMNVVGNTILAMALSGALAGMAGINEVMGVSGNLAMAFSSGYGFDAIALALLGNNHPAGVVLAALLFGTLRNGATRMQVTAGIPIDIISILQAVILMFIAAPAIIRTIYRLKESRAGEGISIRSWGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XPQ5</accession>
    <name>A0A0P6XPQ5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">L-lysine 2,3-aminomutase</fullName>
            <ecNumber evidence="5">5.4.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">ADN00_17610</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>L-lysine = (3S)-3,6-diaminohexanoate</text>
            <dbReference type="Rhea" id="RHEA:19177"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:57434"/>
            <dbReference type="EC" id="5.4.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 14">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the radical SAM superfamily. KamA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.3.2" evidence="5"/>
    <dbReference type="EMBL" id="LGCL01000042">
        <property type="protein sequence ID" value="KPL71216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064365.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000042.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17610"/>
    <dbReference type="EnsemblBacteria" id="KPL71216">
        <property type="protein sequence ID" value="KPL71216"/>
        <property type="gene ID" value="ADN00_17610"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2785"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050066">
        <property type="term" value="F:lysine 2,3-aminomutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025895">
        <property type="entry name" value="LAM_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003739">
        <property type="entry name" value="Lys_aminomutase/Glu_NH3_mut"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022459">
        <property type="entry name" value="Lysine_aminomutase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30538">
        <property type="entry name" value="PTHR30538"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12544">
        <property type="entry name" value="LAM_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004911">
        <property type="entry name" value="DUF160"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00283">
        <property type="entry name" value="L-lysine_2_3-aminomutase_(LAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01070">
        <property type="entry name" value="PLP-dependent"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03820">
        <property type="entry name" value="lys_2_3_AblA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00238">
        <property type="entry name" value="TIGR00238"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="10" id="KW-0408">Iron</keyword>
    <keyword evidence="11 13" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="9 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="16">
        <location>
            <begin position="113"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="413"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="131"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="134"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="14">
        <location>
            <position position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00012144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR004911-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR603739-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KPL71216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="443" mass="50186" checksum="0AF769E2CA43B471" modified="2016-01-20" version="1">MEPFPSRRAPLYKDIPDEKWNDWRWQLSHRLNSLEDFEPVLNLTDSERKALSSKGLFRVDITPYYASLINPDDPHDPIRLQVIPTAGEMVEFTGMMEDSLAEDRHSPVPGLVHRYPDRVLMLVTTQCASYCRYCTRSRIVGDPSATFSRQDFEAQLDYLRRTPQVRDVLLSGGDPLALAPRVLEELLTQLRAIPHIEIIRIGSRIPVFMPMRITDELTDMLQRFHPLWMNIHVNHPNEITAELEQACDKLTRAGIPLGNQSVLLAGVNDCVHIQRKLVQDLVRIRVRPYYLYQCDLVEGAGHFRTPVGKGIEIIEGLRGHTSGYAVPTYVIDAPGGGGKIPLMPNYLVSYSDHKVVVRNYEGYITTYEEPLSYATHDPKTCSFCQNKRVEPGQSGVMGLLDSEDLAIKPQGFDELHNRGGGQHRLRADSHKWKPLGIGSGEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQ03</accession>
    <name>A0A0P6XQ03_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">pre-crRNA processing endonuclease</fullName>
            <ecNumber evidence="2">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_06180</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CRISPR-associated protein Cas5 family. Subtype I-C/Dvulg subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="2"/>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062092.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06180"/>
    <dbReference type="EnsemblBacteria" id="KPL78808">
        <property type="protein sequence ID" value="KPL78808"/>
        <property type="gene ID" value="ADN00_06180"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1737"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043571">
        <property type="term" value="P:maintenance of CRISPR repeat elements"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021124">
        <property type="entry name" value="CRISPR-assoc_prot_Cas5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013422">
        <property type="entry name" value="CRISPR-assoc_prot_Cas5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010155">
        <property type="entry name" value="CRISPR-assoc_prot_Cas5d"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09704">
        <property type="entry name" value="Cas_Cas5d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029950">
        <property type="entry name" value="Cas_CT1134"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01876">
        <property type="entry name" value="cas_Cas5d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02593">
        <property type="entry name" value="CRISPR_cas5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="2" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRNR" id="PIRNR029950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="220" mass="25305" checksum="6E67DCBD167BB680" modified="2016-01-20" version="1">MSYGITIRVSGPYALFTRPEMKVERVSYDVITPSAARGIIEAVYWKPAIRWVIDKIHVLNPIQFTNIRRNEVSEKASTSIATQIMNGSEKPFYISAVDNRQQRASMVLRDVDYVIEAHFELTDKAGEEDTEDKHYPIAMRRLREGQYFHTPCLGTREFAAKVQLVEDKRDIPKSALAGSRSLGWMLYDLDFSNPRDIRPVFFKAEMNEGIIDLTNVEVRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQ62</accession>
    <name>A0A0P6XQ62_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_06115</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78881">
        <property type="protein sequence ID" value="KPL78881"/>
        <property type="gene ID" value="ADN00_06115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="432" mass="46949" checksum="C11CCB911750654B" modified="2016-01-20" version="1">MGLTACGGETAATPEVEAPAAEPVVEATATTASVSEPAAETKEPVKLTFWNNWDSKNGETIQALVDEFNAQNPDIVVENVFQPYGEMTTLLQTSVVSGTNPDLVALDLILIPQLVATGAVEPLDGYIAADAEFDINDFYPLLAEYDVMDGARYAIPMSTNNMQLIWNKDLFAAAGLDPEVPPATWDEMKAMAEQCQNKEQGIVGFEYYTQPTGEGITWQFQVWLWANGGEFLNADNTAAAFNTPEGLGALTFVSDMLAGNGSQPGPWGLFGEQKACMQLDGSWLFGYRADAPFEWGIAPVPAPEGGQTASNVGGEHIFMFNNAKDKEAAWKFIKFMTSAETQLKWDMATGFLPVRKAVGENPEYLQWVNDTEPRMLPFVEGMPYAHTRPATPYYFEVSDAFSREIQLSLLGEKSPADALAAAEAAVNEVLSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQD1</accession>
    <name>A0A0P6XQD1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_03460</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061571.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78964">
        <property type="protein sequence ID" value="KPL78964"/>
        <property type="gene ID" value="ADN00_03460"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="63" mass="7294" checksum="744990890B6E6655" modified="2016-01-20" version="1">MKDNQDPITGTIVETENYIAWKADEPDGETTYHLELNNVTVHFFQEEWEELLQLASLLVKASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQG3</accession>
    <name>A0A0P6XQG3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">ATPase P</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_03715</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061619.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03715"/>
    <dbReference type="EnsemblBacteria" id="KPL79009">
        <property type="protein sequence ID" value="KPL79009"/>
        <property type="gene ID" value="ADN00_03715"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.95"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00371">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017969">
        <property type="entry name" value="Heavy-metal-associated_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006121">
        <property type="entry name" value="HMA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036163">
        <property type="entry name" value="HMA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027256">
        <property type="entry name" value="P-typ_ATPase_IB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00403">
        <property type="entry name" value="HMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55008">
        <property type="entry name" value="SSF55008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01525">
        <property type="entry name" value="ATPase-IB_hvy"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01047">
        <property type="entry name" value="HMA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50846">
        <property type="entry name" value="HMA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="93"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="124"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="322"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="346"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="650"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="domain" description="HMA" evidence="8">
        <location>
            <begin position="6"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50846"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL79009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="704" mass="74707" checksum="D89E0E8E4D1D45AC" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XRD8</accession>
    <name>A0A0P6XRD8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_15475</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15475"/>
    <dbReference type="EnsemblBacteria" id="KPL72222">
        <property type="protein sequence ID" value="KPL72222"/>
        <property type="gene ID" value="ADN00_15475"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="183" mass="20306" checksum="1FC118284B141B8C" modified="2016-01-20" version="1">MLRELALHLLDIAENSVAAQAKNIRITIEEDTCQDTLRMLVVDDGVGMSPELVAKVIDPFTTSRTTRKVGLGIPLLKAAAEACEGWLKIDSAPGAGTTVEVVFKRSHIDRMPLGNLAETFLTLFICTPDVHWLFEYRIDSQEFLFDDVVIKDELQGVPLSEPDVISFVRDYIQSGIESVKSQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XRJ4</accession>
    <name>A0A0P6XRJ4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_15800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063996.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72277">
        <property type="protein sequence ID" value="KPL72277"/>
        <property type="gene ID" value="ADN00_15800"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="95" mass="10699" checksum="C1E70F74B881B337" modified="2016-01-20" version="1">MSDTGSKPKNHTHSTIAGLEELTAFLLSLKWATQIFDGHLRTMQDELEVMKKKIDQALEIVNTVRKGPYAYSDDEVNSAPKNQPKFRIRPGGNSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XSW1</accession>
    <name>A0A0P6XSW1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Arginine--tRNA ligase</fullName>
            <ecNumber evidence="8">6.1.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Arginyl-tRNA synthetase</fullName>
            <shortName evidence="8">ArgRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">argS</name>
        <name evidence="12" type="ORF">ADN00_11625</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg)</text>
            <dbReference type="Rhea" id="RHEA:20301"/>
            <dbReference type="Rhea" id="RHEA-COMP:9658"/>
            <dbReference type="Rhea" id="RHEA-COMP:9673"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78513"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.19"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8 9">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.19" evidence="8"/>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063185.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11625"/>
    <dbReference type="EnsemblBacteria" id="KPL76006">
        <property type="protein sequence ID" value="KPL76006"/>
        <property type="gene ID" value="ADN00_11625"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3800"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004814">
        <property type="term" value="F:arginine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006420">
        <property type="term" value="P:arginyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00671">
        <property type="entry name" value="ArgRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1360.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00123">
        <property type="entry name" value="Arg_tRNA_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001278">
        <property type="entry name" value="Arg-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005148">
        <property type="entry name" value="Arg-tRNA-synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036695">
        <property type="entry name" value="Arg-tRNA-synth_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035684">
        <property type="entry name" value="ArgRS_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008909">
        <property type="entry name" value="DALR_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009080">
        <property type="entry name" value="tRNAsynth_Ia_anticodon-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11956">
        <property type="entry name" value="PTHR11956"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05746">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00750">
        <property type="entry name" value="tRNA-synt_1d"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01038">
        <property type="entry name" value="TRNASYNTHARG"/>
    </dbReference>
    <dbReference type="SMART" id="SM01016">
        <property type="entry name" value="Arg_tRNA_synt_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00836">
        <property type="entry name" value="DALR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47323">
        <property type="entry name" value="SSF47323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55190">
        <property type="entry name" value="SSF55190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00456">
        <property type="entry name" value="argS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Arg_tRNA_synt_N" evidence="11">
        <location>
            <begin position="7"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="DALR_1" evidence="10">
        <location>
            <begin position="470"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="'HIGH' region" evidence="8">
        <location>
            <begin position="133"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001766"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00836"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM01016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KPL76006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="585" mass="66519" checksum="869B08D98FD964ED" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XSW6</accession>
    <name>A0A0P6XSW6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">2,3-bisphosphoglycerate-dependent phosphoglycerate mutase</fullName>
            <shortName evidence="4">BPG-dependent PGAM</shortName>
            <shortName evidence="4">PGAM</shortName>
            <shortName evidence="4">Phosphoglyceromutase</shortName>
            <shortName evidence="4">dPGM</shortName>
            <ecNumber evidence="4 5">5.4.2.11</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">gpmA</name>
        <name evidence="6" type="ORF">ADN00_11730</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">Catalyzes the interconversion of 2-phosphoglycerate and 3-phosphoglycerate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 5">
            <text>(2R)-2-phosphoglycerate = (2R)-3-phosphoglycerate</text>
            <dbReference type="Rhea" id="RHEA:15901"/>
            <dbReference type="ChEBI" id="CHEBI:58272"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="EC" id="5.4.2.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 5">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 3/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the phosphoglycerate mutase family. BPG-dependent PGAM subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.2.11" evidence="4 5"/>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063205.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11730"/>
    <dbReference type="EnsemblBacteria" id="KPL76024">
        <property type="protein sequence ID" value="KPL76024"/>
        <property type="gene ID" value="ADN00_11730"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3821"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00186"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046538">
        <property type="term" value="F:2,3-bisphosphoglycerate-dependent phosphoglycerate mutase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01039">
        <property type="entry name" value="PGAM_GpmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001345">
        <property type="entry name" value="PG/BPGM_mutase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005952">
        <property type="entry name" value="Phosphogly_mut1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11931">
        <property type="entry name" value="PTHR11931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01258">
        <property type="entry name" value="pgm_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00175">
        <property type="entry name" value="PG_MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="2 4" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="8"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="21"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="87"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="114"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="183"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="4">
        <location>
            <position position="9"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="4">
        <location>
            <position position="87"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="4">
        <location>
            <position position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU004512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL76024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="251" mass="29383" checksum="82EC81E735221F10" modified="2016-01-20" version="1">MSRLVLLRHGESVWNRENRFTGWTDVDLTRRGVDEAWQAGRLLRDLNFHFDCAFTSCLKRAVQTLWMVLDAMDLLWVPTCNSWRLNERHYGALQGFNKAEMGERLGKEKVFTWRRTFRGQPPQLSVGDPRHPRFDARYKDVPANLLPAGESLEDTLQRVLPYWQDVICKEVQQNKNVLVVAHGNSLRALVTYLNQIDEEQVPDLQIPTGIPLVYEMDGPNRIERYTYLKNPDQERHLPISHFFAPVRQKNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XT31</accession>
    <name>A0A0P6XT31_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Magnesium chelatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_07285</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Mg-chelatase subunits D/I family. ComM subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062320.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07285"/>
    <dbReference type="EnsemblBacteria" id="KPL78263">
        <property type="protein sequence ID" value="KPL78263"/>
        <property type="gene ID" value="ADN00_07285"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3278"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032508">
        <property type="term" value="P:DNA duplex unwinding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045006">
        <property type="entry name" value="CHLI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001208">
        <property type="entry name" value="MCM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004482">
        <property type="entry name" value="Mg_chelat-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025158">
        <property type="entry name" value="Mg_chelat-rel_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000523">
        <property type="entry name" value="Mg_chelatse_chII-like_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32039">
        <property type="entry name" value="PTHR32039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32039:SF7">
        <property type="entry name" value="PTHR32039:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01078">
        <property type="entry name" value="Mg_chelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13335">
        <property type="entry name" value="Mg_chelatase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01657">
        <property type="entry name" value="MCMFAMILY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00368">
        <property type="entry name" value="TIGR00368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="2">
        <location>
            <begin position="212"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006354"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="511" mass="55313" checksum="5CB8B9E325530CFA" modified="2016-01-20" version="1">MLARVNSCAVIGLEGTIIEVEVDTNPGLPVMVIVGLPDTAVQESRERVQSAIKNAGLVYPRKRVTVNLAPASVRKEGPSYDLPIALGVLAATQQIPLPALENTLVIGELSLDGSLRHVRGVLPMAAIAREQGFQRVIVPEMDAREAALIPGLSVIPAASLGDIVRFLTNQTPIAPFPPVDLSEVPPGLVQTDFSEIKGQEHVKRALEIAAAGGHNLLMVGPPGAGKTLLARALPAILPGMSIEEALDVTRVYSVADQLPGDLPLIRTRPFRAPHHTISHAGLIGGGNWPHPGEVSLAHRGVLFLDELPEFNRRVLEVMRQPLEDKVVTISRAQGSLTFPASFMLIAAMNPCPCGYYGDNLKPCTCSPSTITKYQKRISGPLLDRIDIHITVPRVEFDKLSANRQSESSSTVRQRVESARALQTRRFAGSDGVTPIYCNADMRPAEVRQHCALDETGQNLMRTAMSQLQLSARAFHRVLKLARTIADLAASPSILPQHLAEALQYRPRLEDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XT42</accession>
    <name>A0A0P6XT42_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_07340</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062331.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07340"/>
    <dbReference type="EnsemblBacteria" id="KPL78272">
        <property type="protein sequence ID" value="KPL78272"/>
        <property type="gene ID" value="ADN00_07340"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133210" evidence="2">
        <location>
            <begin position="32"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="317" mass="34941" checksum="78BC014D718DD719" modified="2016-01-20" version="1">MRNHNTLKWMIGGLVCGLVMMACSLSGLAPADTGDSEVDLQKTQLALQATQLSIQADQLAATQTAMAVPAAPAEPAAPPTSAPAEVPTADETKRVNNVNGVYFEYPAWLASDVAASIYDAPPPNADDPYFLIEVDHRVFEFQNYSLADHFLTPLINVYPLEEYQRVNPGAAAQITLLKDLISWQSLGASRPDGLPFLPIFNAAQSFFTKVEFINTDSVNGLRYLTQFQQATYPIQNGQMIYTFQGITTDGKYYISAVFPESHAILEPYDDFEYTAEFEENFLGYLMEIGEQLRAEPDESFNPGLDALDGVIESLRVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XTL3</accession>
    <name>A0A0P6XTL3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">DNA mismatch repair protein MutT</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">ADN00_11320</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063124.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11320"/>
    <dbReference type="EnsemblBacteria" id="KPL76545">
        <property type="protein sequence ID" value="KPL76545"/>
        <property type="gene ID" value="ADN00_11320"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.963"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015577">
        <property type="term" value="F:galactitol transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013853">
        <property type="entry name" value="GatC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013014">
        <property type="entry name" value="PTS_EIIC_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004703">
        <property type="entry name" value="PTS_sugar-sp_permease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37324">
        <property type="entry name" value="PTHR37324"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03611">
        <property type="entry name" value="EIIC-GAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006304">
        <property type="entry name" value="GatC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51104">
        <property type="entry name" value="PTS_EIIC_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0598">Phosphotransferase system</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="6 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="44"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="84"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="129"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="182"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="221"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="263"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="303"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="339"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="363"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="426"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="domain" description="PTS EIIC type-2" evidence="10">
        <location>
            <begin position="9"/>
            <end position="452"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL76545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="461" mass="48823" checksum="78744A85018F7108" modified="2016-01-20" version="1">MDAFLTALKGVIDSLGATVMLPVIIFIIAVAMGAKVGKAFRAGVTIGIAFIGINLVVGLMWGSLSEVGQAMVTNLNIQRDVVDVGWPSAAAIAFGTRVGLWVIPIAILVNVVLLALRLTRTLNVDIWNFWHFAFVGSLVSIASGSLALGLVAAALAAGLALLLADWTAKAVQSFYNLPGISIPHLTTAPGVPFAIVTNWIIDRIPGLRDIEIDPEGIQKRLGVMGEPVILGLIIGLVLGLLAFSNLGDFQTVLVKVLQTGMNLAAVMLLLPRMVQILMEGLIPVSEAAREFMQKRASGREIYIGLDSAILIGHPAALSTSLLLVPVAILLSIILPGNRVILFADLAIIPFVVALFAPLMRGNIFRMVIAGTLELLAGFYIATGMAPLFTSAATEAGFAMPENALQITSIGDGFLWPAWLFTTLGKLGVIGVAIAAVLIVVAWFFYMKNQKAWEVMAGAPQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUL3</accession>
    <name>A0A0P6XUL3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_06435</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062137.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06435"/>
    <dbReference type="EnsemblBacteria" id="KPL78848">
        <property type="protein sequence ID" value="KPL78848"/>
        <property type="gene ID" value="ADN00_06435"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1450">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004680">
        <property type="entry name" value="Cit_transptr-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031312">
        <property type="entry name" value="Na/sul_symport_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03600">
        <property type="entry name" value="CitMHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02080">
        <property type="entry name" value="TrkA_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01271">
        <property type="entry name" value="NA_SULFATE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="28"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="148"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="191"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="422"/>
            <end position="455"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="467"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="498"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="524"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="551"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="590"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="7">
        <location>
            <begin position="231"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="7">
        <location>
            <begin position="320"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL78848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="612" mass="66392" checksum="94C0C65E2F7A8726" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUV4</accession>
    <name>A0A0P6XUV4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 6">Pyruvate dehydrogenase E1 component subunit beta</fullName>
            <ecNumber evidence="3 6">1.2.4.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_03525</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>(R)-N(6)-lipoyl-L-lysyl-[dihydrolipoyllysine-residue acetyltransferase] + H(+) + pyruvate = (R)-N(6)-(S(8)-acetyldihydrolipoyl)-L-lysyl-[dihydrolipoyllysine-residue acetyltransferase] + CO2</text>
            <dbReference type="Rhea" id="RHEA:19189"/>
            <dbReference type="Rhea" id="RHEA-COMP:10480"/>
            <dbReference type="Rhea" id="RHEA-COMP:10481"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83111"/>
            <dbReference type="EC" id="1.2.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="2">Heterodimer of an alpha and a beta chain.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.4.1" evidence="3 6"/>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061584.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03525"/>
    <dbReference type="EnsemblBacteria" id="KPL78976">
        <property type="protein sequence ID" value="KPL78976"/>
        <property type="gene ID" value="ADN00_03525"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.56"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004739">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006086">
        <property type="term" value="P:acetyl-CoA biosynthetic process from pyruvate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027110">
        <property type="entry name" value="PDHB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11624">
        <property type="entry name" value="PTHR11624"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 6 8" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0786">Thiamine pyrophosphate</keyword>
    <feature type="domain" description="Transket_pyr" evidence="7">
        <location>
            <begin position="4"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00016138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU364074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL78976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="323" mass="35364" checksum="45EB810E40A3571B" modified="2016-01-20" version="1">MARITMREAISQALWEEMERDPKVFIMGEEVGVWGGTYAVTKGFYDHFGPDRVRDTPIAEAAIIGAGIGAALTGLRPVTELMTINFAFSAMDHIVNEAAKLHYMFGGQFVLPMVIRTVGGGGRQLGATHSQTPDAIFAHFPGLKVVAPGTPADAKGLLKAAIRSDDPVFFIEHATLYQTRGEVPEGDYIVPIGKSTVQRPGKDVTIVTYSKMLQVSMQAADELSKEGIEVEIVDLRSLRPLDMDPVLESFKKTNRAVVVEEGWRSFGVGSEIASRIYEEAFDYVDAPIKRVAQAEVPLPYNRKLEQMALPQVADVVKAVKEVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XV17</accession>
    <name>A0A0P6XV17_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Uronate isomerase</fullName>
            <ecNumber evidence="4">5.3.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_09230</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>D-glucuronate = D-fructuronate</text>
            <dbReference type="Rhea" id="RHEA:13049"/>
            <dbReference type="ChEBI" id="CHEBI:58720"/>
            <dbReference type="ChEBI" id="CHEBI:59863"/>
            <dbReference type="EC" id="5.3.1.12"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism; pentose and glucuronate interconversion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallo-dependent hydrolases superfamily. Uronate isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.12" evidence="4"/>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062704.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09230"/>
    <dbReference type="EnsemblBacteria" id="KPL77304">
        <property type="protein sequence ID" value="KPL77304"/>
        <property type="gene ID" value="ADN00_09230"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4080"/>
    <dbReference type="UniPathway" id="UPA00246"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008880">
        <property type="term" value="F:glucuronate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006064">
        <property type="term" value="P:glucuronate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003766">
        <property type="entry name" value="Uronate_isomerase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02614">
        <property type="entry name" value="UxaC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL77304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="467" mass="52809" checksum="2586917A5D577F90" modified="2016-01-20" version="1">MMNPNRLFSPEPQLTKLARELYDSVAALPLVCPHGHIDPRLFSDPRATFGSPVDLFIIPDHYVIRMLYSQGIALESLGVPRVDGGSTETDHRSIWRLFCENFCLFRGTPTGIWIQHALSEEFGIQEKPTLANADQLYNAISQKLATPEYTPRALFNRFHIEVLCTTDAATDTLEAHQALQALGWGGRIRPTFRPDAVINLDTPDWRQQIEQLSEVSGVNVIDYSSFLQALEQRRAFFKKMGAVAADHAALTPFTRELPRTDAEAIFQRALKGQFNPEDAVRFTAHMLIEMARMSIEDGLVMQLHPGSLRNHNALIHKRFGADRGSDIPMQTEYTRSLLPLLHKYGNDPRLTLVLFTLDESTYSRELAPLAGHYPAVKLGPPWWFHDSLNGMARYFDQVMETAGLYNTVGFNDDTRAFCSIPARHDVWRRSSANWVAGLVARHIIDLEDARQMMADLAVNLAKRAYHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XV23</accession>
    <name>A0A0P6XV23_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_04160</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061701.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04160"/>
    <dbReference type="EnsemblBacteria" id="KPL79077">
        <property type="protein sequence ID" value="KPL79077"/>
        <property type="gene ID" value="ADN00_04160"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.188"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003777">
        <property type="entry name" value="XdhC_CoxI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027051">
        <property type="entry name" value="XdhC_Rossmann_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13478">
        <property type="entry name" value="XdhC_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02625">
        <property type="entry name" value="XdhC_CoxI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="XdhC_CoxI" evidence="1">
        <location>
            <begin position="11"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="XdhC_C" evidence="2">
        <location>
            <begin position="200"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="350" mass="37816" checksum="594DBC5354DB6648" modified="2016-01-20" version="1">MRDVIDAIRGWHEQGLRMALATVVKVYGSAPRGLGSKMVVNERGEFAGSVSAGCVEGAVIEEARSVLKGGQPRLLEYGISDDLAFSVGLTCGGIIHVFLESLDWEPDEHRVGVKALMEAVEKDETVARVTALAGPLAGRDCLLRMDGSRLGMLPFGEENETVERLALERLRAQQTARLEVALASGAQDVWVEVHAPRPVLVVVGGVHLAIPLVDFAAKLGFHTVVVDARKAFANRERFPHADEVQIGWPAEVLEGMKLHENTFIAVVSHDDKLDIPALKAALNSPARYVGALGSKKTQERRREELRQMGVTEENLRRIHGPIGMDIGAATPGEIAVAILAEMIAARRGKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XWQ4</accession>
    <name>A0A0P6XWQ4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">GMP synthase [glutamine-hydrolyzing]</fullName>
            <ecNumber evidence="9">6.3.5.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">GMP synthetase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Glutamine amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9 12" type="primary">guaA</name>
        <name evidence="12" type="ORF">ADN00_02070</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Catalyzes the synthesis of GMP from XMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + H2O + L-glutamine + XMP = AMP + diphosphate + GMP + 2 H(+) + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:11680"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.5.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Purine metabolism; GMP biosynthesis; GMP from XMP (L-Gln route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.2" evidence="9"/>
    <dbReference type="EMBL" id="LGCL01000008">
        <property type="protein sequence ID" value="KPL79927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02070"/>
    <dbReference type="EnsemblBacteria" id="KPL79927">
        <property type="protein sequence ID" value="KPL79927"/>
        <property type="gene ID" value="ADN00_02070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2845"/>
    <dbReference type="UniPathway" id="UPA00189">
        <property type="reaction ID" value="UER00296"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003922">
        <property type="term" value="F:GMP synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016462">
        <property type="term" value="F:pyrophosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01742">
        <property type="entry name" value="GATase1_GMP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01997">
        <property type="entry name" value="GMP_synthase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00344">
        <property type="entry name" value="GMP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001674">
        <property type="entry name" value="GMP_synth_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004739">
        <property type="entry name" value="GMP_synth_GATase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022955">
        <property type="entry name" value="GMP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025777">
        <property type="entry name" value="GMPS_ATP_PPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00958">
        <property type="entry name" value="GMP_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00884">
        <property type="entry name" value="guaA_Cterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00888">
        <property type="entry name" value="guaA_Nterm"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51553">
        <property type="entry name" value="GMPS_ATP_PPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 9 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 9" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="5 9 10" id="KW-0332">GMP biosynthesis</keyword>
    <keyword evidence="3 9 12" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 9 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 9 10" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GMPS ATP-PPase" evidence="11">
        <location>
            <begin position="193"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="166"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="168"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="220"/>
            <end position="226"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00344"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KPL79927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="518" mass="56627" checksum="04F961703A81615B" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XWU5</accession>
    <name>A0A0P6XWU5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_01980</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000007">
        <property type="protein sequence ID" value="KPL80064.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061287.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000007.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80064">
        <property type="protein sequence ID" value="KPL80064"/>
        <property type="gene ID" value="ADN00_01980"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL80064.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="77" mass="8138" checksum="35A388CDC69E5AEB" modified="2016-01-20" version="1">MSRAAVCPGCQRSYTYPLELEAVRMVGLALLGTCPNCGASVGLNLTWSCRARFIYQPPDPAADPVPADPAASQQSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XXD1</accession>
    <name>A0A0P6XXD1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PadR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01470</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80540.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061186.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80540">
        <property type="protein sequence ID" value="KPL80540"/>
        <property type="gene ID" value="ADN00_01470"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1049"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005149">
        <property type="entry name" value="Tscrpt_reg_PadR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03551">
        <property type="entry name" value="PadR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PadR" evidence="1">
        <location>
            <begin position="21"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80540.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="109" mass="12339" checksum="F588869599503064" modified="2016-01-20" version="1">MNLNQHLPLTEATYYILLSLTQPLHGYGIMQNVKSLSNERVNLAPGTLYGALDNLKKQKLIELLEDEGDSRRKVYTLTNLGRQVMELEYQRLQHLVAISAAVLEGDTNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XXD7</accession>
    <name>A0A0P6XXD7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_01515</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80549.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061195.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01515"/>
    <dbReference type="EnsemblBacteria" id="KPL80549">
        <property type="protein sequence ID" value="KPL80549"/>
        <property type="gene ID" value="ADN00_01515"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1059"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="65"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="149"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="196"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="230"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="275"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL80549.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="310" mass="32703" checksum="135FD61D970EE7FC" modified="2016-01-20" version="1">MSNLFTLPVLLGILYSGIRLATPYLYAAIGETFAQRSGVLNLGVEGIMLMGAYTGFLVAQKSGNLWLGLLAAAATGLLMGLMMAVVSVTLQAEQGISGIGLQLFGLGLSTLLYKKTLGGVESITGFQPIKIPLLGDLPYVGDVLFRHNLLVYGAFLLVPVAAFILNKTTFGLKVRAVGQNPQAADTLGVNVTRIRYTTVMIGGTLAGIAGASLSIALINLFQENMTNGMGFIAVALVYFGSWRPLGVLGGALLFSFVNALQLWVQVLGIPLPSDIAVMMPYLLTIFALAVSVNRTSKPAALTKPFQRGES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XY38</accession>
    <name>A0A0P6XY38_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13955</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74105">
        <property type="protein sequence ID" value="KPL74105"/>
        <property type="gene ID" value="ADN00_13955"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="125" mass="14347" checksum="68625EE194385465" modified="2016-01-20" version="1">MSGRDIYRWVARGAADCPICARLDGEERSLGAWQLTRMPGFHRHCDCRLEPVIDGMPAPPTRPRKREETHPEKKAAPRYENFRGQVAGRKAALKPRIARMSRPRVGKLARRKPYRAPTYKKGAKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XZ10</accession>
    <name>A0A0P6XZ10_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_13715</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063593.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000032.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74352">
        <property type="protein sequence ID" value="KPL74352"/>
        <property type="gene ID" value="ADN00_13715"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL74352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="79" mass="9165" checksum="635089AED9A6BA1D" modified="2016-01-20" version="1">MPSIIIHIHNEDPVLCEVEDLPTPTDQIITVRNPRKRDGKDLTYIDARVTTVIWPISRINFIEVLPGEEEEQIISFVRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y5R7</accession>
    <name>A0A0P6Y5R7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_10190</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76949">
        <property type="protein sequence ID" value="KPL76949"/>
        <property type="gene ID" value="ADN00_10190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="80" mass="9171" checksum="3006A0B842E92A91" modified="2016-01-20" version="1">MMNKSTFLPKHMNLRSLRAGIMKLISAFTCRNSLLEMTAKRPEVSEHPPEVGLPRLTEKGRAAFKAYKRNMQQVLDDLPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y5V8</accession>
    <name>A0A0P6Y5V8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ADN00_10375</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10375"/>
    <dbReference type="EnsemblBacteria" id="KPL76976">
        <property type="protein sequence ID" value="KPL76976"/>
        <property type="gene ID" value="ADN00_10375"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004014">
        <property type="term" value="F:adenosylmethionine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008295">
        <property type="term" value="P:spermidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003826">
        <property type="entry name" value="AdoMetDC_fam_prok"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016067">
        <property type="entry name" value="S-AdoMet_deCO2ase_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017716">
        <property type="entry name" value="S-AdoMet_deCOase_pro-enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33866">
        <property type="entry name" value="PTHR33866"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02675">
        <property type="entry name" value="AdoMet_dc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56276">
        <property type="entry name" value="SSF56276"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03330">
        <property type="entry name" value="SAM_DCase_Bsu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="2" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="9" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0704">Schiff base</keyword>
    <keyword evidence="4" id="KW-0745">Spermidine biosynthesis</keyword>
    <keyword evidence="6" id="KW-0865">Zymogen</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL76976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="102" mass="11669" checksum="28AE20C9617B7863" modified="2016-01-20" version="1">MDARRSRDLFYQAVFESGLTIVSEGYYEFSPHGFTCFLLLAESHASLHAWPEHGYCAIDLFTCNLDLDIQPLINRLQVMFGAADISVRKIEREAEVREPCLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y6R5</accession>
    <name>A0A0P6Y6R5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062679.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09080"/>
    <dbReference type="EnsemblBacteria" id="KPL77278">
        <property type="protein sequence ID" value="KPL77278"/>
        <property type="gene ID" value="ADN00_09080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025495">
        <property type="entry name" value="DUF4386"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14329">
        <property type="entry name" value="DUF4386"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="146"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="168"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="191"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="220" mass="23384" checksum="0B5B104C01844466" modified="2016-01-20" version="1">MKKLQKWGGAAALYQAAAYLAAIVFFLFIANYPSITDPHEKLAFLLENQLGMYGMYTAAYVVFGLALVVLNLALYDRLKTGSPAVMQTAAALGLIWAGTLIASGMVFTMGMKTVLDLYPKDAGQALTIWLTIESVSSGLSSGNGEILGGLWTLLVSLAALRSARLPKALNYLGLAVGFVGLLSAVPPLNDLTAVFGLTQLVWFIGLGITLLQKNSNVFDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y833</accession>
    <name>A0A0P6Y833_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_07990</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062463.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07990"/>
    <dbReference type="EnsemblBacteria" id="KPL77817">
        <property type="protein sequence ID" value="KPL77817"/>
        <property type="gene ID" value="ADN00_07990"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017039">
        <property type="entry name" value="Virul_fac_BrkB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30213">
        <property type="entry name" value="PTHR30213"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03631">
        <property type="entry name" value="Virul_fac_BrkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF035875">
        <property type="entry name" value="RNase_BN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00765">
        <property type="entry name" value="yihY_not_rbn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="53"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="154"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="232"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="273"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL77817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="318" mass="36237" checksum="0395BA4BA6CF2A40" modified="2016-01-20" version="1">MKSLNAIKTAHILSTLEDAYRLTKKGLGSLFLVLRTAYRSFNITMSGETTASLAYYSLFSIFPLALLLIAVASNWLTAQTAQQRVIEYISEIIPISQDLIFNVIKEVVHRRGAFTLISLGSLVWSSSGFFNLLVRNINRPWIGMKPRHFVKTRLQALSIVLVLGSLFLVSILSTTGFEMLNKINFPLWREFLAQTTLRSFLSQFLPQIVRLALLWSLYYWVPNTQIPRLSALAGAVFVSVSWWLLNNAFTWYLNSGFAHYDLVYGSLGRTITLMLWFYFGNYILVFGNHLSAAIARLTRKDNITRSSMVNFDEDDESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y896</accession>
    <name>A0A0P6Y896_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uridine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_08445</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062547.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08445"/>
    <dbReference type="EnsemblBacteria" id="KPL77891">
        <property type="protein sequence ID" value="KPL77891"/>
        <property type="gene ID" value="ADN00_08445"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.691"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004812">
        <property type="term" value="F:aminoacyl-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012675">
        <property type="entry name" value="Beta-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006083">
        <property type="entry name" value="PRK/URK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004095">
        <property type="entry name" value="TGS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012676">
        <property type="entry name" value="TGS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00485">
        <property type="entry name" value="PRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="SSF55186"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81271">
        <property type="entry name" value="SSF81271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51880">
        <property type="entry name" value="TGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TGS" evidence="2">
        <location>
            <begin position="15"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="576" mass="65599" checksum="CEA429C2059D71F9" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y931</accession>
    <name>A0A0P6Y931_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">SAM-dependent methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_07240</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062312.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07240"/>
    <dbReference type="EnsemblBacteria" id="KPL78256">
        <property type="protein sequence ID" value="KPL78256"/>
        <property type="gene ID" value="ADN00_07240"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3268"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019614">
        <property type="entry name" value="SAM-dep_methyl-trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10672">
        <property type="entry name" value="Methyltrans_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltrans_SAM" evidence="4">
        <location>
            <begin position="76"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF10672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL78256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="300" mass="33839" checksum="BC27B3D714EFC365" modified="2016-01-20" version="1">MKPVIEICASPDWRSYELLDSGDGMKLERFGKVVLARPEAEAIWKKALPEKAWEQADGLFISTGEEHGGHWKALKNLPERWQVDYKGLKCWAQLSGSRHLGLFPEQASQWDWVEDQIKAARRPVRVLNLFGYTGMATLSAARAGADVTHVDASRKAILWAKENQTLSGLEHFPVRWLVDDALKFVQREARRGSAYEGLILDPPKFGRGPKGEVWEFYKLIPELLAACQQVMSKEALFVVLTAYSVKASALTLHYAVDEMMKAWEGQTSAGEVVLEEKSAGRLLSTAMFARWRNNSYKEGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YAX3</accession>
    <name>A0A0P6YAX3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_04050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061680.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04050"/>
    <dbReference type="EnsemblBacteria" id="KPL79061">
        <property type="protein sequence ID" value="KPL79061"/>
        <property type="gene ID" value="ADN00_04050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="178" mass="20001" checksum="A2EA4E45D50B705A" modified="2016-01-20" version="1">MQRCKLRQCRAACCLHGVWVGILEAEKILQSAYQIIPYAPPVLQDPASWFEDAQESDPFLPGGMAVHTRVLDNPKHWGGTACGFLRADHKCALQVAANAAGLHPWHFKPLYCILHPLDLDEQGRITLDQTSLLLDEPGSCLRPAPSPIPLWVTFEEELRYFLGDARYDELKNQLNEPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GKL4</accession>
    <name>A0A0N8GKL4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase family 1</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_18350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064502.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70026">
        <property type="protein sequence ID" value="KPL70026"/>
        <property type="gene ID" value="ADN00_18350"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13579">
        <property type="entry name" value="Glyco_trans_4_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="1">
        <location>
            <begin position="15"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="394" mass="43945" checksum="D8E976CBADB3F461" modified="2016-01-20" version="1">MNILYTLTAYPPSTGGAQIHTHQLAQRMNEEHAVSVICQWSQNRTDWLLGTTLRAPGEPHSYEMDGIPVRQIGISQAEKIKLAPWVLAYPVFQGAAIERISETILKEMNAAAPQFDLAHNVRIGREGISAATNKLAKQRNVPFVMTPVHHPAWSGWFHRYYHELYRAADALIALTEAEKQTLAGLGVNETKIHVTGIGPILSEEYDPHRFMEKYGLRQAPAVLFLGQKYAYKGIASLLEATEMVWKKYPETQFWFIGPRTDFSRKLFQQVADPRILELDAVPLQEKTDALAACTLLCVPSAQESFGGVYTEAWSLGKPVIGCPIPAVSEVVNAGENGLLAEQSGEAIAKAILQLLGEPRGAEKMGQRGKMKVDMNFTWEQIVRKTCRVYESLMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GLP7</accession>
    <name>A0A0N8GLP7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sugar ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_14985</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000036">
        <property type="protein sequence ID" value="KPL73090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063843.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000036.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL73090">
        <property type="protein sequence ID" value="KPL73090"/>
        <property type="gene ID" value="ADN00_14985"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1861"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="156"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="192"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="225"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="273"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="328"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="157"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL73090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="364" mass="41155" checksum="AD246BB30D0B548C" modified="2016-01-20" version="1">MSQSKRKFWSKFFVNFTLLLICLVWTVPTIGLLVSSIRTREDIVNSGWWTIFPHREFKTVESVSLPKEVDLEQPIQVAGATVTDRQLRDGYVTPNGQKLIWENRRQRIVSVQDRVWAANTNFTLDNYQNVLSGKEYQYVAPDGSTKTEKGDDLSQAFINTIVVTVPSTVIPILIAAFAAYGFAWMRFPGRKFFFIIVVALLVVPLQLALIPILRDYVKLDLNGTFLAVWLAHTGFGLPLATYLLYNYISTIPRDIFESAFIDGASHFTIFQRLVLPLSVPALASFAIFQFIWVWNDYLVSLVFIGSKPAVQVMTMRLADMVGSRGQDWHVLTAGAFVSMILPLVVFFSLQRYFVRGLMAGSVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMH2</accession>
    <name>A0A0N8GMH2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_13095</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000029">
        <property type="protein sequence ID" value="KPL75290.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063473.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000029.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL75290">
        <property type="protein sequence ID" value="KPL75290"/>
        <property type="gene ID" value="ADN00_13095"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL75290.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="95" mass="10872" checksum="C022A94215258F61" modified="2016-01-20" version="1">MEIKISELSQVCTKLFLHLQELGIETIEISEDFYWNIPKGEVYNPYQRPTQLDLGQLSGDWNDLIKVLINEKEPYANGLVDLAPILRAIGEKVIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMR7</accession>
    <name>A0A0N8GMR7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">POLIIIAc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_11890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063235.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11890"/>
    <dbReference type="EnsemblBacteria" id="KPL76050">
        <property type="protein sequence ID" value="KPL76050"/>
        <property type="gene ID" value="ADN00_11890"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004013">
        <property type="entry name" value="PHP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003141">
        <property type="entry name" value="Pol/His_phosphatase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02811">
        <property type="entry name" value="PHP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00481">
        <property type="entry name" value="POLIIIAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="SSF89550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="POLIIIAc" evidence="1">
        <location>
            <begin position="6"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="354" mass="39368" checksum="BCB11C8422D9AC2D" modified="2016-01-20" version="1">MQELVTNLHIHTQYSDGTGTPSEVLEAATQAGLDVVITTDHNVYISGIDRYLQTGQQRTLLIAGEEIHNPTRDPQKSHLLVMGVNKDLSHFAEDPQELINQVKKNGGICFLAHPYENALALFNESDISWDDWQVTGYTGLELWNGLSEIKNVIHSPLSALFYALNPRLIAHGPDLRTLARWDDLLKQGQRVYAVGGADAHALKMSMGPLKRTIFPYAFHFSAINTHIFTPTGLTGDLARDKQMVFQAFRSGHTFVGYDLAASTRGFRFSAQGKDCTAWMGDEIKLNGGVTLQARLPFAADVRLMVNGAALRTWRNTTTATLIVNEPGAYRIEAYTQYQGKMRGWIFSNPIFVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GN27</accession>
    <name>A0A0N8GN27_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_10070</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76930.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062873.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10070"/>
    <dbReference type="EnsemblBacteria" id="KPL76930">
        <property type="protein sequence ID" value="KPL76930"/>
        <property type="gene ID" value="ADN00_10070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="10"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="84"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL76930.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="138" mass="15614" checksum="5DA8BF6598404ACF" modified="2016-01-20" version="1">MESHRVKDWMTKNPITVSSSVTIPDAYWLMINNKIRRLLVVDDGKLVGIVTIEDLRQKIPFTTFAIDAVKASDILSRCPVRQVMSTEPKTTTPDTQLIEAAQFMLEQKISTLPVMEGKQVVGIITEGDFFRAFVELMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GN46</accession>
    <name>A0A0N8GN46_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ABC transmembrane type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_10810</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10810"/>
    <dbReference type="EnsemblBacteria" id="KPL77082">
        <property type="protein sequence ID" value="KPL77082"/>
        <property type="gene ID" value="ADN00_10810"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2640"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025966">
        <property type="entry name" value="OppC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12911">
        <property type="entry name" value="OppC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="100"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="140"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="178"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="292"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="98"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL77082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="324" mass="35447" checksum="570AE68C4B7F72E5" modified="2016-01-20" version="1">MTQKRESLFADAFRRLLRNRAAVIGGSIIIILIALAVLAPYIAPAPFDKQVLEDQNTIPQWLTSVFPTMAPYARISNNYPLGADYVGRDLLSRIIYGARISLTVAFIGPIISLIIGVTYGSIAGFFGGRVDNIMMRFVDVLYAFPSLLFIILLMAFFRSTFSKPDPGSITYAISQLDAKMGGMLFIFIGIGLTAWETMARLTRGQVLSVREKEYVEAARTIGATNGRIMFNHILPNIVGPLVVAETLAIPSYISTEAFLSFIGLGVNPPTPSWGAMISDGAQMVRTYPNQTIFPALGLAITMFAFNFLGDGLRDALDPRLRGTQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GPJ0</accession>
    <name>A0A0N8GPJ0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_00385</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060973.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00385"/>
    <dbReference type="EnsemblBacteria" id="KPL81034">
        <property type="protein sequence ID" value="KPL81034"/>
        <property type="gene ID" value="ADN00_00385"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="5">
        <location>
            <begin position="6"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="4">
        <location>
            <begin position="118"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL81034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="328" mass="37147" checksum="D8B7FA1F687829DE" modified="2016-01-20" version="1">MTEQTPTIKQVISDYIDMVAQARSEKTARTYQNGLSVFASVLDVNGIDPFKAGIEQLPEDSITWFTAALKDYAPATERLYLTAATNFFEFLVSDNILEINLPRIRMLVRQRARKPGIRLPQFPTFEIEKVLDYAERLNTKPAEGEEERLRNYRDRAFLLLLADSGLRVHEACNLRRGDINWDSGQALVIGKGNREAVARFSTRSLKALSEYLRMRATVDGISGKELLSLPLFARHDRGAGKKIKPISTVTGRNIVKERVTEALGPDAVGRITPHSFRHFFVTKVLKASGNLKLAQELARHKNIAVTQRYAHLMDEELDQGYRAIFEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WQ96</accession>
    <name>A0A0P6WQ96_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_15525</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063943.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72228">
        <property type="protein sequence ID" value="KPL72228"/>
        <property type="gene ID" value="ADN00_15525"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="194" mass="21960" checksum="FFFABA3DF8C20B08" modified="2016-01-20" version="1">MTKKATITTEATANKIQKLAAKLRSVAYKFSRSTGVYVDPEDIYSDLVTAILNQAQVDPEFINQTDAYIIQFAKFQASHICQKAQVYLRFVDELGNVVDPEDEDQAEDLEMTAEVREKLLQNIQAVETEVLYNEMVETFVQTATSNLKQSELETVYMLYMGYKPAEIAREANISRAAVSMRIDKIAKKLKGVEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WR76</accession>
    <name>A0A0P6WR76_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_17030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064252.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17030"/>
    <dbReference type="EnsemblBacteria" id="KPL71401">
        <property type="protein sequence ID" value="KPL71401"/>
        <property type="gene ID" value="ADN00_17030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.170">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005186">
        <property type="entry name" value="FlaG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035924">
        <property type="entry name" value="FlaG-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03646">
        <property type="entry name" value="FlaG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF160214">
        <property type="entry name" value="SSF160214"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL71401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="113" mass="12658" checksum="75B09F6E50F39508" modified="2016-01-20" version="1">METPPIQSIHSSDTSDRETAAVTLKQAQQALARQAAARQNDQAAAETERQKDQQAEVSQARMQMNVQLKFKVDAETNDVTILILDRQSHRVIRTIPSEEISKLKEGDLVELFA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WSS2</accession>
    <name>A0A0P6WSS2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">4Fe-4S ferredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_16420</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064125.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16420"/>
    <dbReference type="EnsemblBacteria" id="KPL72060">
        <property type="protein sequence ID" value="KPL72060"/>
        <property type="gene ID" value="ADN00_16420"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3726"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00037">
        <property type="entry name" value="Fer4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13247">
        <property type="entry name" value="Fer4_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="3"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="43"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="77"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="107"/>
            <end position="136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL72060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="159" mass="17555" checksum="0579A848B54459D0" modified="2016-01-20" version="1">MGKFIMIHPDKCTGCKNCVIACSFEKEKQFRPAAARIHVYTWEREGISVPMMCQQCSDAPCVSVCPTGAMHRVSGSSLIEYDASKCIRCRMCVQACPFGNAVYDSVTDAILKCDTCNDNPACVAACPVNAIEYIEENISTRSRKKAFAKKFKDAFQEVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WSS7</accession>
    <name>A0A0P6WSS7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_16470</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064135.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72069">
        <property type="protein sequence ID" value="KPL72069"/>
        <property type="gene ID" value="ADN00_16470"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="117" mass="13500" checksum="39CA5BFED17E6941" modified="2016-01-20" version="1">MWFFDGLMTVREYNKANPYNIYFIRYWFCNFVIRIQFLKSNSCFLVNNDGGIEDEKTVDMAGWNLDLLSNCVWRPNPRQARADPFANAHPSAAGFIANSAPHFNRCYPPAIKPASKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WSV4</accession>
    <name>A0A0P6WSV4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH arsR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_18210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064475.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70001">
        <property type="protein sequence ID" value="KPL70001"/>
        <property type="gene ID" value="ADN00_18210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01022">
        <property type="entry name" value="HTH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="5"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="130" mass="15248" checksum="64989319D3E7AC20" modified="2016-01-20" version="1">MSAKSVENPFDSAAKFFKLFSHPARLQILNEISKEEACVCHLEAILGYRQAYISQHLMALREAGLIHDRRDGWNVYYQVSDPRVKELMDLIHLRFLDDDDLQSLRKTKICHCPKCTHETLPEKWIPEHEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WSY4</accession>
    <name>A0A0P6WSY4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Putative pre-16S rRNA nuclease</fullName>
            <ecNumber evidence="2">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_15150</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Could be a nuclease involved in processing of the 5'-end of pre-16S rRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the YqgF HJR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="2"/>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063879.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15150"/>
    <dbReference type="EnsemblBacteria" id="KPL72169">
        <property type="protein sequence ID" value="KPL72169"/>
        <property type="gene ID" value="ADN00_15150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004518">
        <property type="term" value="F:nuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000967">
        <property type="term" value="P:rRNA 5'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16964">
        <property type="entry name" value="YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00651">
        <property type="entry name" value="Nuclease_YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005227">
        <property type="entry name" value="YqgF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006641">
        <property type="entry name" value="YqgF/RNaseH-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037027">
        <property type="entry name" value="YqgF/RNaseH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33317">
        <property type="entry name" value="PTHR33317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03652">
        <property type="entry name" value="RuvX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00732">
        <property type="entry name" value="YqgFc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00250">
        <property type="entry name" value="RNAse_H_YqgF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0540">Nuclease</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0690">Ribosome biogenesis</keyword>
    <feature type="domain" description="YqgFc" evidence="4">
        <location>
            <begin position="3"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="96"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00732"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL72169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="139" mass="14707" checksum="2D14F2BF225FC899" modified="2016-01-20" version="1">MSGRILAVDPGEKRIGLAISDETACIANPLGVVTHTARDADAQTVAQIAAENQAARIIVGQALDASGEVGPAARKAQRFADALRLHTDLPVELWDESGSTKAAQSARREMGVSRKKRSGHLDDLAAAIILQTYLDAKHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WVN4</accession>
    <name>A0A0P6WVN4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Intracellular sulfur oxidation protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_18110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DsrF/TusC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL69987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064454.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18110"/>
    <dbReference type="EnsemblBacteria" id="KPL69987">
        <property type="protein sequence ID" value="KPL69987"/>
        <property type="gene ID" value="ADN00_18110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027396">
        <property type="entry name" value="DsrEFH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003787">
        <property type="entry name" value="Sulphur_relay_DsrE/F-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017462">
        <property type="entry name" value="Sulphur_relay_TusC/DsrF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38780">
        <property type="entry name" value="PTHR38780"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02635">
        <property type="entry name" value="DrsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75169">
        <property type="entry name" value="SSF75169"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL69987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="117" mass="13654" checksum="A7C037B9C8084F05" modified="2016-01-20" version="1">MKKILFVIYQAPCGTIWPNEGFRTAFGMYGEDIEPEVLFIDQGVVSVAKETEPSKLGLFSLKMVQKYIKKYGTKVFAEKESLEKFKVRELDENFQSEVISRHQAKEMIHNYDFVIFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WVP9</accession>
    <name>A0A0P6WVP9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutaredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_18235</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064479.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18235"/>
    <dbReference type="EnsemblBacteria" id="KPL70005">
        <property type="protein sequence ID" value="KPL70005"/>
        <property type="gene ID" value="ADN00_18235"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2951"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005243">
        <property type="entry name" value="Redox_disulphide_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36450">
        <property type="entry name" value="PTHR36450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13192">
        <property type="entry name" value="Thioredoxin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037031">
        <property type="entry name" value="Redox_disulphide_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00412">
        <property type="entry name" value="redox_disulf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin-like_fold" evidence="3">
        <location>
            <begin position="2"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="11"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="14"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="2">
        <location>
            <begin position="11"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR037031-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR037031-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL70005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="79" mass="8828" checksum="6353BDE2D7ED72AD" modified="2016-01-20" version="1">MVNIKILGMGCANCKRLEAVTRKVVEKLEIEAEFEKVTEMDQILSYSILSTPGLVINEKLFAAGRIPSESEITEWLKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WVQ9</accession>
    <name>A0A0P6WVQ9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13695</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74349">
        <property type="protein sequence ID" value="KPL74349"/>
        <property type="gene ID" value="ADN00_13695"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1315"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="30"/>
            <end position="261"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="270" mass="30514" checksum="8417D8DE6BE595FC" modified="2016-01-20" version="1">MKPYLNYTGLWKERLGIAYLDPAPDRQRVIVLLHGLGADAESWVFQYPVLIAAGFRPLAPDLPGFGRSAAYAQRWSVKRTAEKLAAWLAALGVERFSLVGHSMGGAVAQELALICAERVEKLVLVNTFAHLRIRFSGETRYLTRRFVTLNFRGLDQQAAQVAERVFPREDQTIWRELVVEKILQASPRVYRQAMLSLAVFDARRKAKKLSMPALVVTSEEDTTIAPSIQTELASRLPNARQVRIEQSGHAVLIDQAEEFNRTLLTFLRER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WVR8</accession>
    <name>A0A0P6WVR8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_18385</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064509.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70032">
        <property type="protein sequence ID" value="KPL70032"/>
        <property type="gene ID" value="ADN00_18385"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024623">
        <property type="entry name" value="YtxH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12732">
        <property type="entry name" value="YtxH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="72" mass="7901" checksum="E0172ACA80746C60" modified="2016-01-20" version="1">MKKIENFIFGAMLGGLIGAGLAILLAPTSGKSLRDEVQGYIDNTVSEVRNAGIQRRQELEIELTRLREPKSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WX39</accession>
    <name>A0A0P6WX39_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_13475</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SorC transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74843">
        <property type="protein sequence ID" value="KPL74843"/>
        <property type="gene ID" value="ADN00_13475"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007324">
        <property type="entry name" value="Sugar-bd_dom_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04198">
        <property type="entry name" value="Sugar-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r4_2" evidence="3">
        <location>
            <begin position="9"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar-bind" evidence="2">
        <location>
            <begin position="56"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL74843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="315" mass="34233" checksum="DC78AFD73523D031" modified="2016-01-20" version="1">MGTLIQIATLYYLEDRSQQEIADELGVSRSLVALYLKKARDQGIIRFSIINPQDNLEDLACGIQELAGLHHVVVVPSSHNSSTLTRRSLAGVVARHLEDSLKDGDVIGLGWGRTVAEVINLLAPSRPRLVDVVPLLGESSSGISGSFSQINQMVMNTAHAFNGRAHFLLVPLLVSSNTLRTSLYEDEAVKGVSSLWDRLDYAIMGVGSIVPQDGEVVYIGPENLSMFEQQGAVGDVVVRYFNIQGSYIQTDFHDRLIGIDLPQLTRAKHRIALASGIEKARATVGVLRSGVCTDLFVDEILARAVLEELSSAEKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WXB1</accession>
    <name>A0A0P6WXB1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Band 7 protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_17905</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000043">
        <property type="protein sequence ID" value="KPL70907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064410.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000043.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70907">
        <property type="protein sequence ID" value="KPL70907"/>
        <property type="gene ID" value="ADN00_17905"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2163"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="SSF117892"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="domain" description="PHB" evidence="2">
        <location>
            <begin position="37"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL70907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="300" mass="34016" checksum="F81CB99B87C295C8" modified="2016-01-20" version="1">MSDFMQFLFAAAITFMAMWLVMPIFLFLLRRIGLYTIVQEGTCQVFILFGRVIGILREPGLHILPFKLGLNAFLVNWLGNRRVLDMRLDQQYLRSNPVNSEEGAPMGVGIWYEMYISDPVAYLFKNVDPRGSLAANVSNAVVRSLSNMPLENMLINRHYMSHAVREEVSPRSHEWGYKLGSVYIRKVHFRDAGMIHQIEAKVVNRLRQVTSAIKQDGANQVNIITSTAERLAAVEFAKAAAIRPRILGEAMKAIAEDPEISNVMFEILETQRILESKSKLTLVPPRSELLTQLIAARKPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WXZ2</accession>
    <name>A0A0P6WXZ2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase_C39_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_16925</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064232.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16925"/>
    <dbReference type="EnsemblBacteria" id="KPL71385">
        <property type="protein sequence ID" value="KPL71385"/>
        <property type="gene ID" value="ADN00_16925"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039564">
        <property type="entry name" value="Peptidase_C39-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13529">
        <property type="entry name" value="Peptidase_C39_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_C39_2" evidence="2">
        <location>
            <begin position="108"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="73"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL71385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="429" mass="48210" checksum="BE10F6550836BE1E" modified="2016-01-20" version="1">MVKNKQQLILIGAAIVAAALLVIAFTPLGESLTFHLNQWKYRIDYALNPPEEVVFVPRTTNPAVRVETFTPTALPAETQNAATPTVGQSPTPAATPTPPPAQANITGIRYIDQHYGQNKCAPATLAMALSYWGWDENPSVMDPFLMPFEFDKNVMPYELVSFVAEQTQQSVISRTGGTIELLERLISAGFPVMVEKGVYERDLSGKVSWMGHYQVVSGYDRAQQRFTTQDSYHTANYIVSYEDMQRGWRSFNYTFLVIYNPEKEADLFQVLGSYADVNAANQAAMQIAQTESASLEGQAKFFALFNYGSSLVSLQDYYGASQAYDQAWAYYAGLPAEDRPWRIMWYQTGPYFAYYYSGRYQDLIDLATQTIDAASQPYLEESWYWRARGYAAAGMVEEAVSDLRTSLQYHPEFSPSVAMLQELGYTAEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WY00</accession>
    <name>A0A0P6WY00_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">Glutamate racemase</fullName>
            <ecNumber evidence="2 7">5.1.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">murI</name>
        <name evidence="8" type="ORF">ADN00_14540</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Provides the (R)-glutamate required for cell wall biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>L-glutamate = D-glutamate</text>
            <dbReference type="Rhea" id="RHEA:12813"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:29986"/>
            <dbReference type="EC" id="5.1.1.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="7">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the aspartate/glutamate racemases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.1.3" evidence="2 7"/>
    <dbReference type="EMBL" id="LGCL01000035">
        <property type="protein sequence ID" value="KPL73559.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14540"/>
    <dbReference type="EnsemblBacteria" id="KPL73559">
        <property type="protein sequence ID" value="KPL73559"/>
        <property type="gene ID" value="ADN00_14540"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2074"/>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008881">
        <property type="term" value="F:glutamate racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00258">
        <property type="entry name" value="Glu_racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015942">
        <property type="entry name" value="Asp/Glu/hydantoin_racemase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001920">
        <property type="entry name" value="Asp/Glu_race"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018187">
        <property type="entry name" value="Asp/Glu_racemase_AS_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033134">
        <property type="entry name" value="Asp/Glu_racemase_AS_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004391">
        <property type="entry name" value="Glu_race"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21198:SF2">
        <property type="entry name" value="PTHR21198:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01177">
        <property type="entry name" value="Asp_Glu_race"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53681">
        <property type="entry name" value="SSF53681"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00067">
        <property type="entry name" value="glut_race"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00923">
        <property type="entry name" value="ASP_GLU_RACEMASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00924">
        <property type="entry name" value="ASP_GLU_RACEMASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0133">Cell shape</keyword>
    <keyword evidence="6 7" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="5 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4 7" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="15"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="47"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="79"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="7">
        <location>
            <begin position="190"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="7">
        <location>
            <position position="78"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="7">
        <location>
            <position position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023316"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL73559.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="277" mass="29832" checksum="F4F552C25EDEA608" modified="2016-01-20" version="1">MSVEKETSLAVGVFDSGVGGLSVLRELQAQLPNQEMIYFADQAHVPYGPRPLDEVRDFSEEITRFLIEQGARLVVVACNTASAAALHFLRQRFAGVPFVGMEPAVKPAAEQTRSGLVGVLATPATFQGELYASVVERFARGVRVLQDTCPGLVEEIEAGNLNGEKTRQILERALRPMLEQGVDTIVLGCTHYPFVIPLIETITGPAVRVINPAPAVARQAGRLLAERGWLNTAQGGTRYFTSGEASLLAGQVRGMLGQPGAVDARKAVWAGKRLRVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WYA7</accession>
    <name>A0A0P6WYA7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Flagellar motor switch protein FliM</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">ADN00_17215</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Bacterial flagellum basal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the FliM family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71428.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064288.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17215"/>
    <dbReference type="EnsemblBacteria" id="KPL71428">
        <property type="protein sequence ID" value="KPL71428"/>
        <property type="gene ID" value="ADN00_17215"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17908">
        <property type="entry name" value="FliM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028976">
        <property type="entry name" value="CheC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001689">
        <property type="entry name" value="Flag_FliM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001543">
        <property type="entry name" value="FliN-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036429">
        <property type="entry name" value="SpoA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02154">
        <property type="entry name" value="FliM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01052">
        <property type="entry name" value="FliMN_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002888">
        <property type="entry name" value="FliM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00955">
        <property type="entry name" value="FLGMOTORFLIM"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101801">
        <property type="entry name" value="SSF101801"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103039">
        <property type="entry name" value="SSF103039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01397">
        <property type="entry name" value="fliM_switch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="7" id="KW-0283">Flagellar rotation</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FliMN_C" evidence="10">
        <location>
            <begin position="269"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL71428.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="343" mass="38347" checksum="7FB3ABDBB18CA3BA" modified="2016-01-20" version="1">MLSQQEIDALLSGAIEIEGNEGEERVNLAELIGSEPGAVGKSAKTKEGKKVQPYNFWSPNRFSKEQMRAVELVHEDLAERLTTSLPTFLRFNLRPRLVHTEQGRFHDFLKDSGAGTLFHMITLAPLPGQIVLTISPNVSLMILEQRLGGRIEGQVQERDLTDIDQSLLRGLVEHMLNDLKGAWSKVASIEPALEDSTVNSNWVQMMMGTERVMLLTFELTLMETTGTMSVFIPFRTLKPIANELNPHVWISGRKEQTQDPAVRENAMKSLSNVKLPVKVIMGSANLTVREVLELSVGDVIRLDTGVEQLFKMQIANQTLFNVRIGKANNRLVAKVHSVARDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WYR8</accession>
    <name>A0A0P6WYR8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Xylose isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_14380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000034">
        <property type="protein sequence ID" value="KPL73751.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063722.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000034.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL73751">
        <property type="protein sequence ID" value="KPL73751"/>
        <property type="gene ID" value="ADN00_14380"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0413">Isomerase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="1">
        <location>
            <begin position="42"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL73751.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="324" mass="36110" checksum="FEE50B052C33F0E1" modified="2016-01-20" version="1">MMKGLGVGVWTFGMGSERYVSDGYKPYLTLEERIAKVSTLKGISGIEVTFPNDVNADTAHKFRALINQYGLSLCGMGVELVCDKEWQSGSFASPDPRRREKAISLTRAAMDMAAEFGVSNVSLWLGQDGFDYVFQDDYAAAWQRLVEGVREAANHRSDVTLGLEYKTSEPKMACYINSGGKALALAQATGKANVGITLDVGHAINARENPAEIAAVLLAEKRLFHIHLNDNYSWSDDDMPVGSVHFLQYVELLYWLKKLNYAGWLSLDLYPYRDDPIEACQTSIHFVSKMQNLVNQPNFDRLIEENRASGSRSVRAVYELLLGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZ95</accession>
    <name>A0A0P6WZ95_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH luxR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_16350</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72049">
        <property type="protein sequence ID" value="KPL72049"/>
        <property type="gene ID" value="ADN00_16350"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3711"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041617">
        <property type="entry name" value="TPR_MalT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17874">
        <property type="entry name" value="TPR_MalT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="807"/>
            <end position="872"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL72049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="874" mass="98252" checksum="055C493FB627D47C" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-08-12" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZC2</accession>
    <name>A0A0P6WZC2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_16680</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064173.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72104">
        <property type="protein sequence ID" value="KPL72104"/>
        <property type="gene ID" value="ADN00_16680"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3781"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="415" mass="46900" checksum="F715BF366C892887" modified="2016-01-20" version="1">MKERPFILAVLPGLAPSTLMDVVTPLKQLQQAGQIHARVTLDWLTTTEEVNQADLVVFCRNNNPAYDWSGFCVEKCIPYIYDLDDNLFAIPASTPLGQYANRPDVIETLKGYLRGAALVRVYSPALREVVAPLNANTRLVQPPIDWGVLDGLTRKSGRGLKMVYPTSRGSADDLAEIFVPAIQQILKDHPRGVEIYFLGAPVPRELKAFRQVRHWKFDLDYEQYLRRFYQEGFDIGLAPLKDDLFHQCKTNNKYREFAACGIAGIYSKTTLYQQSVRHEQTGLLVENTAAAWHQAIRTLIENPELRRSIQASALQDAQNTYPREAFAGEWLAQIRHVLEEQPIPMAAPADQKQPAAPQGVEAPTSRFGRVKNLAGRLRQNGIGYLVESIRWKMVKAQHQAALKRINRDRKSSINL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZI2</accession>
    <name>A0A0P6WZI2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_15520</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063942.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72227">
        <property type="protein sequence ID" value="KPL72227"/>
        <property type="gene ID" value="ADN00_15520"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="84" mass="9373" checksum="5692796AE5CAF029" modified="2016-01-20" version="1">MLRLQIKGSEILKMSGEANNHRLALKARVSYPTVDRWINRSQNVQSIDLAALANLLLDGIGLSPDELLARPLGDFFELVEVDQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZV6</accession>
    <name>A0A0P6WZV6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_13925</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063636.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000033.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13925"/>
    <dbReference type="EnsemblBacteria" id="KPL74099">
        <property type="protein sequence ID" value="KPL74099"/>
        <property type="gene ID" value="ADN00_13925"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL74099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="329" mass="36953" checksum="1216DB545D192B1F" modified="2016-01-20" version="1">MDSNVCVWRGQAVFIWQVKQCALPLPAHSAEAHEHLAVTARQAGLAYVPVKVADGPYRYNQVAGGSGGLGWRDEILPGLLNAFTRAGLRRVGWHYLYGAEPEREADTAAERMVTLGLEGYILDAESEYKLAGADAARRFMRRLRKLAGNIPLALCSYRFPSYHREFPWQAFLDEMDGQRGDAHMPQVYWVGDARPDGPALQLQRSMKELRALKDLPVAPIGAAYGQQLESGYWRPSPDQMRAFSRAAQSAGCAGLSWWSWDSLRAKDGSAPGAEGKLGWWDAIAGLGADGAKRRLRFPSRWSSAWCAWRRRRARQVGRYEQEERQNEFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X1M5</accession>
    <name>A0A0P6X1M5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 8 10">Uracil-DNA glycosylase</fullName>
            <shortName evidence="8">UDG</shortName>
            <ecNumber evidence="4 8 10">3.2.2.27</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">ung</name>
        <name evidence="12" type="ORF">ADN00_13455</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 8 10">Excises uracil residues from the DNA which can arise as a result of misincorporation of dUMP residues by DNA polymerase or due to deamination of cytosine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>Hydrolyzes single-stranded DNA or mismatched double-stranded DNA and polynucleotides, releasing free uracil.</text>
            <dbReference type="EC" id="3.2.2.27"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 8 10">Belongs to the uracil-DNA glycosylase (UDG) superfamily. UNG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.2.27" evidence="4 8 10"/>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74839.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063539.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000031.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13455"/>
    <dbReference type="EnsemblBacteria" id="KPL74839">
        <property type="protein sequence ID" value="KPL74839"/>
        <property type="gene ID" value="ADN00_13455"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1179"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004844">
        <property type="term" value="F:uracil DNA N-glycosylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006284">
        <property type="term" value="P:base-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd10027">
        <property type="entry name" value="UDG-F1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00148">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002043">
        <property type="entry name" value="UDG_fam1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018085">
        <property type="entry name" value="Ura-DNA_Glyclase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005122">
        <property type="entry name" value="Uracil-DNA_glycosylase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036895">
        <property type="entry name" value="Uracil-DNA_glycosylase-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11264">
        <property type="entry name" value="PTHR11264"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03167">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00986">
        <property type="entry name" value="UDG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52141">
        <property type="entry name" value="SSF52141"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00628">
        <property type="entry name" value="ung"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00130">
        <property type="entry name" value="U_DNA_GLYCOSYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8 10" id="KW-0227">DNA damage</keyword>
    <keyword evidence="7 8 10" id="KW-0234">DNA repair</keyword>
    <keyword evidence="6 8 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDG" evidence="11">
        <location>
            <begin position="48"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="8 9">
        <location>
            <position position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KPL74839.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="223" mass="25383" checksum="76ABE10F7B0243DB" modified="2016-01-20" version="1">MPIPDSWLPALVGETTQPYYEQLYRFVSEERRKYRVYPPAEDVFNALRYTPFERVRVVIIGQDPYHDENQAHGLAFSVRPGVAVPPSLLNIYKELRDDVQFRIPNHGCLIPWAEQGVLLLNAVLTVRAHQANSHQGKGWESFTDAVLRAINARESRVVFLLWGSYAQRKAEWIDSNRHTVLKAPHPSPLSASRGFFGCRHFSKANLALQSAGLPPINWQLADL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X2W8</accession>
    <name>A0A0P6X2W8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Pyruvate-flavodoxin oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">ADN00_14330</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="12">Binds 3 [4Fe-4S] clusters per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000034">
        <property type="protein sequence ID" value="KPL73744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063715.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000034.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14330"/>
    <dbReference type="EnsemblBacteria" id="KPL73744">
        <property type="protein sequence ID" value="KPL73744"/>
        <property type="gene ID" value="ADN00_14330"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1385"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
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    <sequence length="1182" mass="129087" checksum="6C11C5445605EA59" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X3X0</accession>
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        <name type="scientific">Ornatilinea apprima</name>
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            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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    <proteinExistence type="predicted"/>
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            <begin position="900"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="domain" description="Cation_ATPase_N" evidence="8">
        <location>
            <begin position="11"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL76055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="934" mass="101252" checksum="806ADEB62978077E" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X3Y3</accession>
    <name>A0A0P6X3Y3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HTH tetR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_12120</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063279.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76083">
        <property type="protein sequence ID" value="KPL76083"/>
        <property type="gene ID" value="ADN00_12120"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3900"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025996">
        <property type="entry name" value="TetR_C_WHG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13305">
        <property type="entry name" value="TetR_C_33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="5">
        <location>
            <begin position="12"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="4">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL76083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="229" mass="24715" checksum="283A5E1F7F34B207" modified="2016-01-20" version="1">MSPRPRRSEQIQDLSEQILAAAWQQIAESGAPALSLRAIARALGITAPAIYNYYPDRDALVTALIVDAFTSFGDSQAAALQGIPAADHQQRLHALGAAYRQWAIDHPERYHLIFGTPIAGYVAPAEITMPAAACALNILIGELDAAHRAGKLNTTHLSPITSDLAAMFTAWQAERGAASEVALYQAFCVWSAIHGLVFLEISHQFPPMITDPSAFCQSAIQTLVRQTIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X4I2</accession>
    <name>A0A0P6X4I2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Peptidase S54</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_11105</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063082.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11105"/>
    <dbReference type="EnsemblBacteria" id="KPL76512">
        <property type="protein sequence ID" value="KPL76512"/>
        <property type="gene ID" value="ADN00_11105"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.917"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1540.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022764">
        <property type="entry name" value="Peptidase_S54_rhomboid_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035952">
        <property type="entry name" value="Rhomboid-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01694">
        <property type="entry name" value="Rhomboid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144091">
        <property type="entry name" value="SSF144091"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="100"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="123"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="155"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="domain" description="Rhomboid" evidence="6">
        <location>
            <begin position="58"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL76512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="232" mass="25762" checksum="C93A3D6CB4AFC458" modified="2016-01-20" version="1">MLPIRDTIRSRSFPLVTWMLIALNALVFFLELGMGPAELDALISGFGLVPARLSVFNPFTWLPLLTHMFLHGGWVHFLGNVWTLAIFGDNVEDRLGSGRFLLFYLIGGVAAGLIQSWSTPNSLIPSIGASGAIAAVMGAYFFYYPRARVITLVPLFVLPWFVEIPALIYLGFWFVSQLFSGLLSLAAAQGMQMGGIAWWAHIGGFLFGLLLAGPLQARQKKPAWYQDEYYPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X4J6</accession>
    <name>A0A0P6X4J6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_13685</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063587.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000032.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74348">
        <property type="protein sequence ID" value="KPL74348"/>
        <property type="gene ID" value="ADN00_13685"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039968">
        <property type="entry name" value="YghO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41368">
        <property type="entry name" value="PTHR41368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL74348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="375" mass="43640" checksum="E4524294F2737BB8" modified="2016-01-20" version="1">MIQVKVVDTRNKQDVNQFISVPFNLYKNCPQWVPPFISDVKFMLNRDKHPFFERSDGDFLIATKGNEVVGRLMVMEHKPFNAYHQCKKMSFTMFDSIDDQEVANALFEYGFEWGRKRGLNEVVGPKGMCSFDGYGILESGFDQRQMMTMSSYNYPYYPKLMENMGFEKEVDFVSCSLPMEKFILPEKIHEVARRVQERGTLKVKNFKSRRELIDYAPTIGEAYNNTFVNNWEYYPLSPAEVKYLLSQLMSVLDYRLIKIITHEEKMIGFLVAFPDISDALQRQKGRITPWGIVDLLTTMKRTKYVTLNGAGILPDFQGRGGNALLYSEMYKTIHDFGFVHAELTQVAETTRQMRKDLINVGGVEYKNHRVYHRAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X545</accession>
    <name>A0A0P6X545_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alkylhydroperoxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_18170</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL69995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064467.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18170"/>
    <dbReference type="EnsemblBacteria" id="KPL69995">
        <property type="protein sequence ID" value="KPL69995"/>
        <property type="gene ID" value="ADN00_18170"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2937"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051920">
        <property type="term" value="F:peroxiredoxin activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029032">
        <property type="entry name" value="AhpD-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004675">
        <property type="entry name" value="AhpD_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003779">
        <property type="entry name" value="CMD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02627">
        <property type="entry name" value="CMD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69118">
        <property type="entry name" value="SSF69118"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00778">
        <property type="entry name" value="ahpD_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CMD" evidence="1">
        <location>
            <begin position="26"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02627"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL69995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="115" mass="12259" checksum="7BFFEDA34D60242B" modified="2016-01-20" version="1">MTDYVGLYQHANERLEQLGSEAPGPMSGFARLHKKTVENGALDTKTKELMALAIGIAVHCEGCIAYHTHDAIEAGATREELIETISVAIMMGGGPASVYAAHAMDAIEQFLAISE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X546</accession>
    <name>A0A0P6X546_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peptide ABC transporter ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_10250</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062907.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10250"/>
    <dbReference type="EnsemblBacteria" id="KPL76960">
        <property type="protein sequence ID" value="KPL76960"/>
        <property type="gene ID" value="ADN00_10250"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="15"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="62"/>
            <end position="69"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL76960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="341" mass="38641" checksum="DF3ECC631355C044" modified="2016-01-20" version="1">MNEQTPTPISDDILVKVENIKKWYPVQTTFLDQLFTQQRDFVRAVDGVSFTIKRGEAFGLAGESGSGKSTIGRLTLGLEELTEGRAIFDGIDYSTLSVDENRKLRRRMQVIFQDPMASLNPRMSIGSAITQPLRIHYPEKAAEHRDMVLSIMDKVGLTPPLFFYNKYPHQISGGQRQRIVIARALVTQPELVLADEPIAMADVSVRAQLLDLMVQLKKEFNLTYLFITHDLATAKYICDRIGVLYLGRMAEVGPLREVYANPLHPYTQALMAAVPKPNPHKRRTYPMPEGEIPNPINPPSGCRFHPRCPFAKDECSRVEPELRELRPDHLVACHFAEQFVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="39" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X596</accession>
    <name>A0A0P6X596_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 20">Methionine synthase</fullName>
            <ecNumber evidence="6 20">2.1.1.13</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="19 20">5-methyltetrahydrofolate--homocysteine methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="30" type="ORF">ADN00_18645</name>
    </gene>
    <organism evidence="30 31">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="30 31" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="30 31">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="18 20">Catalyzes the transfer of a methyl group from methyl-cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 20">
            <text>(6S)-5-methyl-5,6,7,8-tetrahydrofolate + L-homocysteine = (6S)-5,6,7,8-tetrahydrofolate + L-methionine</text>
            <dbReference type="Rhea" id="RHEA:11172"/>
            <dbReference type="ChEBI" id="CHEBI:18608"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:58199"/>
            <dbReference type="EC" id="2.1.1.13"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 20 23">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 20 22">
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 20">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-methionine from L-homocysteine (MetH route): step 1/1.</text>
    </comment>
    <comment type="domain">
        <text evidence="20">Modular enzyme with four functionally distinct domains. The isolated Hcy-binding domain catalyzes methyl transfer from free methylcobalamin to homocysteine. The Hcy-binding domain in association with the pterin-binding domain catalyzes the methylation of cob(I)alamin by methyltetrahydrofolate and the methylation of homocysteine. The B12-binding domain binds the cofactor. The AdoMet activation domain binds S-adenosyl-L-methionine. Under aerobic conditions cob(I)alamin can be converted to inactive cob(II)alamin. Reductive methylation by S-adenosyl-L-methionine and flavodoxin regenerates methylcobalamin.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the vitamin-B12 dependent methionine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="30">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.13" evidence="6 20"/>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064549.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18645"/>
    <dbReference type="EnsemblBacteria" id="KPL70068">
        <property type="protein sequence ID" value="KPL70068"/>
        <property type="gene ID" value="ADN00_18645"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3038"/>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00081"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008705">
        <property type="term" value="F:methionine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042558">
        <property type="term" value="P:pteridine-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1240.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.196.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003759">
        <property type="entry name" value="Cbl-bd_cap"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006158">
        <property type="entry name" value="Cobalamin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036724">
        <property type="entry name" value="Cobalamin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011005">
        <property type="entry name" value="Dihydropteroate_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003726">
        <property type="entry name" value="HCY_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036589">
        <property type="entry name" value="HCY_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011822">
        <property type="entry name" value="MetH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036594">
        <property type="entry name" value="Meth_synthase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000489">
        <property type="entry name" value="Pterin-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004223">
        <property type="entry name" value="VitB12-dep_Met_synth_activ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037010">
        <property type="entry name" value="VitB12-dep_Met_synth_activ_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02310">
        <property type="entry name" value="B12-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02607">
        <property type="entry name" value="B12-binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02965">
        <property type="entry name" value="Met_synt_B12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00809">
        <property type="entry name" value="Pterin_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02574">
        <property type="entry name" value="S-methyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000381">
        <property type="entry name" value="MetH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01018">
        <property type="entry name" value="B12-binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47644">
        <property type="entry name" value="SSF47644"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51717">
        <property type="entry name" value="SSF51717"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52242">
        <property type="entry name" value="SSF52242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56507">
        <property type="entry name" value="SSF56507"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82282">
        <property type="entry name" value="SSF82282"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02082">
        <property type="entry name" value="metH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50974">
        <property type="entry name" value="ADOMET_ACTIVATION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51332">
        <property type="entry name" value="B12_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51337">
        <property type="entry name" value="B12_BINDING_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50970">
        <property type="entry name" value="HCY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50972">
        <property type="entry name" value="PTERIN_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 20" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 20 22" id="KW-0846">Cobalamin</keyword>
    <keyword evidence="17 20 21" id="KW-0170">Cobalt</keyword>
    <keyword evidence="13 20 21" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16 20" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="8 20 24" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="31" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0677">Repeat</keyword>
    <keyword evidence="12 20 22" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="11 20 24" id="KW-0808">Transferase</keyword>
    <keyword evidence="15 20 21" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Hcy-binding" evidence="25">
        <location>
            <begin position="7"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="Pterin-binding" evidence="26">
        <location>
            <begin position="347"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="domain" description="B12-binding N-terminal" evidence="29">
        <location>
            <begin position="636"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="domain" description="B12-binding" evidence="28">
        <location>
            <begin position="736"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="domain" description="AdoMet activation" evidence="27">
        <location>
            <begin position="879"/>
            <end position="1174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Methylcob(III)alamin binding" evidence="22">
        <location>
            <begin position="746"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="22">
        <location>
            <begin position="1159"/>
            <end position="1160"/>
        </location>
    </feature>
    <feature type="binding site" evidence="21 23">
        <location>
            <position position="235"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21 23">
        <location>
            <position position="301"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="21 23">
        <location>
            <position position="302"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" description="axial binding residue" evidence="21">
        <location>
            <position position="749"/>
        </location>
        <ligand>
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </ligand>
        <ligandPart>
            <name>Co</name>
            <dbReference type="ChEBI" id="CHEBI:27638"/>
        </ligandPart>
    </feature>
    <feature type="binding site" evidence="22">
        <location>
            <position position="794"/>
        </location>
        <ligand>
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="22">
        <location>
            <position position="854"/>
        </location>
        <ligand>
            <name>methylcob(III)alamin</name>
            <dbReference type="ChEBI" id="CHEBI:28115"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="22">
        <location>
            <position position="1104"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001956"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010398"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022628"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00023285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00025552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00031040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="PIRNR" id="PIRNR000381"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="21">
        <source>
            <dbReference type="PIRSR" id="PIRSR000381-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="22">
        <source>
            <dbReference type="PIRSR" id="PIRSR000381-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="23">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="24">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="25">
        <source>
            <dbReference type="PROSITE" id="PS50970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="26">
        <source>
            <dbReference type="PROSITE" id="PS50972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="27">
        <source>
            <dbReference type="PROSITE" id="PS50974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="28">
        <source>
            <dbReference type="PROSITE" id="PS51332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="29">
        <source>
            <dbReference type="PROSITE" id="PS51337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="30">
        <source>
            <dbReference type="EMBL" id="KPL70068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="31">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="1174" mass="129831" checksum="49097DE476E7111D" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5F9</accession>
    <name>A0A0P6X5F9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphoserine aminotransferase</fullName>
            <ecNumber evidence="6">2.6.1.52</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Phosphohydroxythreonine aminotransferase</fullName>
            <shortName evidence="6">PSAT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">serC</name>
        <name evidence="9" type="ORF">ADN00_07440</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the reversible conversion of 3-phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4-phosphonooxybutanoate to phosphohydroxythreonine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>2-oxoglutarate + 4-(phosphooxy)-L-threonine = (R)-3-hydroxy-2-oxo-4-phosphooxybutanoate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:16573"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58452"/>
            <dbReference type="ChEBI" id="CHEBI:58538"/>
            <dbReference type="EC" id="2.6.1.52"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 6 7">
            <text>2-oxoglutarate + O-phospho-L-serine = 3-phosphooxypyruvate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:14329"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:18110"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57524"/>
            <dbReference type="EC" id="2.6.1.52"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
        <text evidence="6">Binds 1 pyridoxal phosphate per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 6 7">Amino-acid biosynthesis; L-serine biosynthesis; L-serine from 3-phospho-D-glycerate: step 2/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Cofactor biosynthesis; pyridoxine 5'-phosphate biosynthesis; pyridoxine 5'-phosphate from D-erythrose 4-phosphate: step 3/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 6">Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.52" evidence="6"/>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062352.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07440"/>
    <dbReference type="EnsemblBacteria" id="KPL78289">
        <property type="protein sequence ID" value="KPL78289"/>
        <property type="gene ID" value="ADN00_07440"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3312"/>
    <dbReference type="UniPathway" id="UPA00135">
        <property type="reaction ID" value="UER00197"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00244">
        <property type="reaction ID" value="UER00311"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004648">
        <property type="term" value="F:O-phospho-L-serine:2-oxoglutarate aminotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006564">
        <property type="term" value="P:L-serine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008615">
        <property type="term" value="P:pyridoxine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00160">
        <property type="entry name" value="SerC_aminotrans_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020578">
        <property type="entry name" value="Aminotrans_V_PyrdxlP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022278">
        <property type="entry name" value="Pser_aminoTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43247">
        <property type="entry name" value="PTHR43247"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000525">
        <property type="entry name" value="SerC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01364">
        <property type="entry name" value="serC_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00595">
        <property type="entry name" value="AA_TRANSFER_CLASS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-0664">Pyridoxine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0718">Serine biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_5" evidence="8">
        <location>
            <begin position="5"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="6">
        <location>
            <begin position="75"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="6">
        <location>
            <begin position="231"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>L-glutamate</name>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="99"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="6">
        <location>
            <position position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL78289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="356" mass="39813" checksum="D9C867DDA788B6D7" modified="2016-01-20" version="1">MKKHNFYAGPSILPQYTIDESIAAMKDFAGTGLSILEVSHRSKEFDAVMAETEALFKDLLNVPQEYRVIFVGGGASTQFFTVPYNLLQTRAAYLNTGEWATKAIEEAEIFGEVVVVASSKNKNFTYIPRDFTIPTDVDYFHFTSNNTIYGTEIREDFDSPVTLVSDMSSDILSRPVDVSKYGLIYGGAQKNLGPAGVTFVILKESILGKVERRIPTMVDYRTHIKKNSLFNTPPVAAVYSCLMTLRWLKNLGGVEVMEKINIAKSSLLYETIESSKFFRPTIPNPQDRSRMNVCFVLKDEYKDLEKPFLEFASGRGMVGIKGHRSVGGFRASLYNALPLESVQALVDCMKEFEAAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X6T9</accession>
    <name>A0A0P6X6T9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sporulation initiation inhibitor Soj</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_11815</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063220.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76036">
        <property type="protein sequence ID" value="KPL76036"/>
        <property type="gene ID" value="ADN00_11815"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_31" evidence="1">
        <location>
            <begin position="3"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="263" mass="28423" checksum="C19E545B8028B224" modified="2016-01-20" version="1">MAKIYTLVNQKGGVGKTTSAINLGAYLGYYGQKVLLIDLDPQSNATSSLGIDKNTVRTGTYEVLLGSAPISPHILHNPRLKISLLPSSPALAGAEVELADLDHQEKRLSTAIEPVLSRYDYILIDCPPSLSMLTINGLVAAKDGVLIPVQCEYLALEGLGMLTQTLDRVRSSFSMNLPVRGVLLTMFDGRTRLALDVVTEVKKYFPDQVFQTVIPRSIRVAEAPSYGQPLSTYAPESSAAKAYANLAREVLGQDGIMIPEGME</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X771</accession>
    <name>A0A0P6X771_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">30S ribosomal protein S21</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpsU</name>
        <name evidence="5" type="ORF">ADN00_17760</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bS21 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000043">
        <property type="protein sequence ID" value="KPL70891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064392.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000043.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70891">
        <property type="protein sequence ID" value="KPL70891"/>
        <property type="gene ID" value="ADN00_17760"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.1150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00358">
        <property type="entry name" value="Ribosomal_S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001911">
        <property type="entry name" value="Ribosomal_S21"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038380">
        <property type="entry name" value="S21_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01165">
        <property type="entry name" value="Ribosomal_S21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00030">
        <property type="entry name" value="S21p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL70891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="63" mass="7659" checksum="B7F6196FE0FB2FF3" modified="2016-01-20" version="1">MATVVLRANESQDQLLKRFRKKVVKSGVLSTVRRKRWFVSKSELRRVEKKKAIRRIKRRQIEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7W4</accession>
    <name>A0A0P6X7W4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_04425</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HAD-like hydrolase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061745.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04425"/>
    <dbReference type="EnsemblBacteria" id="KPL79112">
        <property type="protein sequence ID" value="KPL79112"/>
        <property type="gene ID" value="ADN00_04425"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006357">
        <property type="entry name" value="HAD-SF_hydro_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13344">
        <property type="entry name" value="Hydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000915">
        <property type="entry name" value="PGP-type_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01460">
        <property type="entry name" value="HAD-SF-IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="12"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR000915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000915-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="265" mass="28959" checksum="6FA622044385E2AC" modified="2016-01-20" version="1">MKLSHVKGLLIDVDGTLLRSKAALPGVELFFPFLRSKGVKFCIATNNSVVTAEQYQRFFEQLGAPISEAEILTSSAAMRYYLERHFPQGGKAYVIGREGLRQAVRQAGFEVLEGMEAAADVAVVGGDPHFTYDHLKYACLHIQNGAVFLGTNPDVLYPSDEGLLPEVGTTLAALKAATGVEARVIGKPEKHLFEAALQRLGLEARETAMLGDRLDTDIAGAKRIGMASILVETGVDNRDSAQQHNIHPDMIVRDLPELMARWEDQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X8H7</accession>
    <name>A0A0P6X8H7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH cro/C1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_06775</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000018">
        <property type="protein sequence ID" value="KPL78423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06775"/>
    <dbReference type="EnsemblBacteria" id="KPL78423">
        <property type="protein sequence ID" value="KPL78423"/>
        <property type="gene ID" value="ADN00_06775"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="19"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="79" mass="9162" checksum="D2C7850E3E3E1D75" modified="2016-01-20" version="1">MLRGEKEPSRRFQLDSLDIKNIREKYNLTQQQFAAMLGISVRTLRNWEQGRRVPKGPAMVLLRVADKHPKAVLDVVSEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X8I3</accession>
    <name>A0A0P6X8I3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SHSP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_06835</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000018">
        <property type="protein sequence ID" value="KPL78432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062234.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000018.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78432">
        <property type="protein sequence ID" value="KPL78432"/>
        <property type="gene ID" value="ADN00_06835"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00011">
        <property type="entry name" value="HSP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="SSF49764"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SHSP" evidence="4">
        <location>
            <begin position="34"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="137"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL78432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="157" mass="18437" checksum="C1BD8168FF574E96" modified="2016-01-20" version="1">MSEITRYNPFREMLELSRAMDDLFYRDYPSLRGEVDFDWKLPLDVVEREDGYIVRASVPGIDPKDLEITYSEHTLTIKGETQMEESKENERYHMRERRFGRFLRSISLPDPVAQDKIEASYENGVLELHLPKAEEARPRRISVLDKGSGKRIEAKTK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X8V0</accession>
    <name>A0A0P6X8V0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Tryptophan--tRNA ligase</fullName>
            <ecNumber evidence="2">6.1.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_03215</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.2" evidence="2"/>
    <dbReference type="EMBL" id="LGCL01000014">
        <property type="protein sequence ID" value="KPL79359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061530.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000014.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03215"/>
    <dbReference type="EnsemblBacteria" id="KPL79359">
        <property type="protein sequence ID" value="KPL79359"/>
        <property type="gene ID" value="ADN00_03215"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2054"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004830">
        <property type="term" value="F:tryptophan-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006436">
        <property type="term" value="P:tryptophanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00806">
        <property type="entry name" value="TrpRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002306">
        <property type="entry name" value="Trp-tRNA-ligase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01039">
        <property type="entry name" value="TRNASYNTHTRP"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00233">
        <property type="entry name" value="trpS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL79359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="329" mass="36936" checksum="2FA8300DCC982304" modified="2016-01-20" version="1">MSNKKGRVFSGARPTGRQHLGNYLGAIKNYVALQDEYNCVYCIVDVHALTTVETTQNLRQNTIEMALDWLAAGIRPEESIVFIQSHVPEVMELHTYLSMVTPLGKLTDLPTFKEKIRLHPNNVNYGLVGYPVLMSADILLYRASAVPVGVDQAPHIEFARETVRSFNFRYNCDVLVEPQMKITQVPKVIGIDGVQKMSKSLDNHIEIAATAEETQKRVMQMVTDPQRQRRSDPGNPDVCNVFSFHKIFSTPEEVEMVNTECRKAGIGCVDCKKMLAKNLNASLAPFRARRAELEKDTDAVWDVLMDGAKRARVIAEETMTDVRQAIGLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X8X4</accession>
    <name>A0A0P6X8X4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF190 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_02765</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0166 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000013">
        <property type="protein sequence ID" value="KPL79377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061434.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000013.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02765"/>
    <dbReference type="EnsemblBacteria" id="KPL79377">
        <property type="protein sequence ID" value="KPL79377"/>
        <property type="gene ID" value="ADN00_02765"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2186"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003793">
        <property type="entry name" value="DUF190"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02641">
        <property type="entry name" value="DUF190"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="SSF54913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF190" evidence="2">
        <location>
            <begin position="9"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="113" mass="12744" checksum="25C2DCD2054B718B" modified="2016-01-20" version="1">MRLEENGYLLRIFIGEADKHEGKLLYEWLVIQARQAGLAGATVLRGIMGFGPSSRIQTSKILMLSEDMPVVVEIVDSKENLEEFLARVENAIVEGLVTLEKATVRLYRGRPRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X8Y0</accession>
    <name>A0A0P6X8Y0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_11655</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063191.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11655"/>
    <dbReference type="EnsemblBacteria" id="KPL76012">
        <property type="protein sequence ID" value="KPL76012"/>
        <property type="gene ID" value="ADN00_11655"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13492">
        <property type="entry name" value="GAF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAC" evidence="3">
        <location>
            <begin position="251"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="308"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL76012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="531" mass="58870" checksum="1AE12D2F397D7157" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9I3</accession>
    <name>A0A0P6X9I3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_09850</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062830.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09850"/>
    <dbReference type="EnsemblBacteria" id="KPL76895">
        <property type="protein sequence ID" value="KPL76895"/>
        <property type="gene ID" value="ADN00_09850"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="358" mass="40087" checksum="BD7E0D095CA94F9C" modified="2016-01-20" version="1">MFVGGEFYADARWLLDEASISTGKMIFLNGGKACLIVIADYLRAHGVEKILLPAYLCPTIVNTLEGRGLACAYYPIRPDFSIDLDALAHKSAGYQAVYFINYFGFSQPAPARGFLADLRQKGVLVIEDNAQAGFVEQSTGDFIFNSVRKLAAFNGGYLSTALDVTASIEKYRGLPNRHLPLIREYRERLADYLYRGAGSHTELEQMLRLAETYYESDLVVEGDPQERRQIERLDWKGIKQARRQNYAYLLSLIAGVEELAPVFPALQEDNMPLGLPVYVRGISRDWLLDELGNAGIGLTIHWDELLRDPRLNGDPAAVGMASQILTLVIDQRTSHKQMDYLVQTCLDCIRKAKGKPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9Z5</accession>
    <name>A0A0P6X9Z5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_16825</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064214.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL71369">
        <property type="protein sequence ID" value="KPL71369"/>
        <property type="gene ID" value="ADN00_16825"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132952" evidence="1">
        <location>
            <begin position="18"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL71369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="272" mass="29952" checksum="4D6EE58DA85A0627" modified="2016-01-20" version="1">MKKMLYFVAILALMAMACNLGGTPKPSATQIAPTMVVVQEQPTIAPTFTLVPTLVEPTIAPMEQPTEVPAVAPTEIPPAEPEAQWVSWVVAGDASKNFTTFYDNKIVLDLPKAETYSYVRLEGIEYDDVYAEVTAETMTGSAMNGIAVICRASEAGWYELRVTTVGQNAGSWMMYFYNYRLKEQGKNPYERLIKTIDRINSIDIVNGYRVNTIGLSCEGNEIRPYINGVEQIYNKTIVTDDNLTSGMVGFGGMSYNVGPVKMEFTDFAAGMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAP7</accession>
    <name>A0A0P6XAP7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ROK (NagC/XylR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062689.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09140"/>
    <dbReference type="EnsemblBacteria" id="KPL77288">
        <property type="protein sequence ID" value="KPL77288"/>
        <property type="gene ID" value="ADN00_09140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="401" mass="42681" checksum="1A2CAA555F5904E0" modified="2016-01-20" version="1">MPHTKATHQQTKLLNRDLVLKMIFEHDEISRAEVARLTKLTRATVSDMVASLIGEGLVEEIGFGSSIGGKAPILLRLVADSRYLIGLNLGQDKFIGAVVNLRGEIKETIEMPVDGIDGEEALQLVYHILDQLTGKGWQPLVGIGIGTPGLVNTQEGVVVNAVNLDWRDLPLASLLEARYNLPVSILNDSQATAIGEFVYGRTLSSDGSLIVITARHGIGAGILISGRLFQGDGGGAGEIGHVVVQENGSLCRCGKHGCLETLASASAVVRRARALAGDYPGSSLAASSSAITLDTVRQAWDAQDPLAEQVVLDSARYLGASLAGLISVLNIHRIVITGDMECFGKRWLQAVGESMTAHALARMAQETILEFGTLNFKACILGASAYMLLESYSLLFLNPAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAV5</accession>
    <name>A0A0P6XAV5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_09815</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062824.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76889">
        <property type="protein sequence ID" value="KPL76889"/>
        <property type="gene ID" value="ADN00_09815"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="69" mass="8040" checksum="4591F2856ABA5A7F" modified="2016-01-20" version="1">MSTDSDRPHIIAKYTGEIAYQNGSTGKFEALLEKNDGEWKIFNITFLEPPKKLHKYETPNLKTLFHEKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XB69</accession>
    <name>A0A0P6XB69_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA pseudouridine synthase B</fullName>
            <ecNumber evidence="4">5.4.99.25</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridine(55) synthase</fullName>
            <shortName evidence="4">Psi55 synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridylate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA-uridine isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">truB</name>
        <name evidence="7" type="ORF">ADN00_02685</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Responsible for synthesis of pseudouridine from uracil-55 in the psi GC loop of transfer RNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>uridine(55) in tRNA = pseudouridine(55) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:42532"/>
            <dbReference type="Rhea" id="RHEA-COMP:10101"/>
            <dbReference type="Rhea" id="RHEA-COMP:10102"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="EC" id="5.4.99.25"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the pseudouridine synthase TruB family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.25" evidence="4"/>
    <dbReference type="EMBL" id="LGCL01000012">
        <property type="protein sequence ID" value="KPL79438.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061417.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000012.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02685"/>
    <dbReference type="EnsemblBacteria" id="KPL79438">
        <property type="protein sequence ID" value="KPL79438"/>
        <property type="gene ID" value="ADN00_02685"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2365"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106029">
        <property type="term" value="F:tRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02573">
        <property type="entry name" value="PseudoU_synth_EcTruB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01080">
        <property type="entry name" value="TruB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002501">
        <property type="entry name" value="PsdUridine_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014780">
        <property type="entry name" value="tRNA_psdUridine_synth_TruB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032819">
        <property type="entry name" value="TruB_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13767">
        <property type="entry name" value="PTHR13767"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16198">
        <property type="entry name" value="TruB_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01509">
        <property type="entry name" value="TruB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00431">
        <property type="entry name" value="TruB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="TruB_N" evidence="5">
        <location>
            <begin position="35"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="domain" description="TruB_C_2" evidence="6">
        <location>
            <begin position="183"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01509"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL79438.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="303" mass="33540" checksum="9067EB5F9F7C524F" modified="2016-01-20" version="1">MSDMENYEIKNTVSGVLVIDKPVGMTSHDVVQVVRKGTNIRRAGHTGTLDPRASGVLVVLIGPAVRLSEYVSASDKRYQGIIRLGSRTDTYDADGTVTDTSPVDITEEQFENALSQFIGEIEQVPPPYSAVKIKGKKAYQLARQGEEVDLEPRKITVHSLELLEWAPPEAVVDIYCSSGTYVRSLAHDLGNVLGCGAHLIGLRRTKSGRFTLRDAVPLQKLREAFDDGSWYQYLIPAAEALSEWPALELDDDQLDVVRHGHRIPAEEKLGNMVRGVSAQGELVALLSYEEDTNEYQPRKVFFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBC2</accession>
    <name>A0A0P6XBC2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SUI1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_10890</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SUI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063025.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10890"/>
    <dbReference type="EnsemblBacteria" id="KPL77054">
        <property type="protein sequence ID" value="KPL77054"/>
        <property type="gene ID" value="ADN00_10890"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2657"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11567">
        <property type="entry name" value="YciH_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001950">
        <property type="entry name" value="SUI1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005872">
        <property type="entry name" value="SUI1_arc_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036877">
        <property type="entry name" value="SUI1_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01253">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037511">
        <property type="entry name" value="Transl_init_SUI1_pro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55159">
        <property type="entry name" value="SSF55159"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01158">
        <property type="entry name" value="SUI1_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50296">
        <property type="entry name" value="SUI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0810">Translation regulation</keyword>
    <feature type="domain" description="SUI1" evidence="4">
        <location>
            <begin position="54"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL77054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="122" mass="12857" checksum="1183D0202E40E538" modified="2016-01-20" version="1">MKMTPRREDARTVYSTELGRVCPDCGRPIDACACRKKPAAAAGDGNVRVRLEKKGRGGKAVSLVSGLPLAEEDLRKLAAELKKRCGAGGAVKDGQIEIQGDHRDTLVAALLALGYRAKKAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBP3</accession>
    <name>A0A0P6XBP3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein-methionine-sulfoxide reductase heme-binding subunit MsrQ</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Flavocytochrome MsrQ</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">msrQ</name>
        <name evidence="9" type="ORF">ADN00_15125</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, using the quinone pool of the respiratory chain.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="7">Binds 1 FMN per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
        <text evidence="7">Binds 1 heme b (iron(II)-protoporphyrin IX) group per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Heterodimer of a catalytic subunit (MsrP) and a heme-binding subunit (MsrQ).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the MsrQ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063874.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15125"/>
    <dbReference type="EnsemblBacteria" id="KPL72165">
        <property type="protein sequence ID" value="KPL72165"/>
        <property type="gene ID" value="ADN00_15125"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.727"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030091">
        <property type="term" value="P:protein repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01207">
        <property type="entry name" value="MsrQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022837">
        <property type="entry name" value="MsrQ-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36964">
        <property type="entry name" value="PTHR36964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0249">Electron transport</keyword>
    <keyword evidence="7" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="7" id="KW-0288">FMN</keyword>
    <keyword evidence="7" id="KW-0349">Heme</keyword>
    <keyword evidence="5 7" id="KW-0408">Iron</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="116"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="154"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="177"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="domain" description="Ferric oxidoreductase" evidence="8">
        <location>
            <begin position="49"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL72165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="220" mass="25005" checksum="988D2E91F44B9B70" modified="2016-01-20" version="1">MVLSIGRHRFSGIQVLVHAASWLPLVWIFLTYKFDPIKVNPIQTVTQQTGRIALIWFLLSLACTPAVTLLGFNPALKVRRALGLYAFFYAVLHFLTFSVLDYRLDLPQIFDLLVSKRYLIAGTLAFLILIALAITSTQQSMRLLGKIWQRLHQLAYPGAVLVILHYLWAAKAGTPGPYFYGAVLFGLLLLRVPLIKRWITTHKPPWLRQISQRLARPASK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBQ7</accession>
    <name>A0A0P6XBQ7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Elongation factor P</fullName>
            <shortName evidence="7">EF-P</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">efp</name>
        <name evidence="11" type="ORF">ADN00_15230</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Protein biosynthesis; polypeptide chain elongation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7 8">Belongs to the elongation factor P family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063894.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15230"/>
    <dbReference type="EnsemblBacteria" id="KPL72183">
        <property type="protein sequence ID" value="KPL72183"/>
        <property type="gene ID" value="ADN00_15230"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00345"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04470">
        <property type="entry name" value="S1_EF-P_repeat_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05794">
        <property type="entry name" value="S1_EF-P_repeat_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00141">
        <property type="entry name" value="EF_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015365">
        <property type="entry name" value="Elong-fact-P_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020599">
        <property type="entry name" value="Transl_elong_fac_P/YeiP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013185">
        <property type="entry name" value="Transl_elong_KOW-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001059">
        <property type="entry name" value="Transl_elong_P/YeiP_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013852">
        <property type="entry name" value="Transl_elong_P/YeiP_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011768">
        <property type="entry name" value="Transl_elongation_fac_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30053">
        <property type="entry name" value="PTHR30053"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01132">
        <property type="entry name" value="EFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08207">
        <property type="entry name" value="EFP_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09285">
        <property type="entry name" value="Elong-fact-P_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005901">
        <property type="entry name" value="EF-P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01185">
        <property type="entry name" value="EFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00841">
        <property type="entry name" value="Elong-fact-P_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00038">
        <property type="entry name" value="efp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01275">
        <property type="entry name" value="EFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7 11" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="6 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EFP" evidence="10">
        <location>
            <begin position="67"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="Elong-fact-P_C" evidence="9">
        <location>
            <begin position="129"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL72183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="187" mass="20941" checksum="62B3175BDAC350AE" modified="2016-01-20" version="1">MIDVNDLRKGVTFLLDGSLYKVLDYHHNKPGRGNATIRVKAKDLRTGTTLEKTFNSGFRVEDVRLDYHNVQYLYNDGAFYYFMDVETFEQPAIPAKIVEEAAGYLTENLEVKLTFFNNEAIDIELPTSVDLVVTEAEAAVRGDTATGVTKKVKVETGIYVDVPAFIVQGQKIRISTSTGEYVTRVSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-04-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XC11</accession>
    <name>A0A0P6XC11_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chemotaxis protein CheY</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_09395</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062734.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77328">
        <property type="protein sequence ID" value="KPL77328"/>
        <property type="gene ID" value="ADN00_09395"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="5"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="145" mass="16422" checksum="5AB463206CCDE022" modified="2016-01-20" version="1">MNEKIILLVEDNPSDIELTKRALAKAHIMNELVVAENGLEALEYLFGLEKNGEHPEPLPAIVLLDLKLPGVDGLEVLRKIRENPYTHRQPVVILTSSREEQDIAASYDLGVNSYIRKPVDFYQFAEAIQQLGLYWLVLNENPPSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XC41</accession>
    <name>A0A0P6XC41_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_08975</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08975"/>
    <dbReference type="EnsemblBacteria" id="KPL77356">
        <property type="protein sequence ID" value="KPL77356"/>
        <property type="gene ID" value="ADN00_08975"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004671">
        <property type="term" value="F:protein C-terminal S-isoprenylcysteine carboxyl O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007269">
        <property type="entry name" value="ICMT_MeTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04140">
        <property type="entry name" value="ICMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="54"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="84"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="143"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL77356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="203" mass="22792" checksum="494A0902B0D0FAB6" modified="2016-01-20" version="1">MTRRWSWWEAWVYAAINILGFVASRAIAGRKHPDLLAERARMLHHDDPEPWDRWLAPLVGLGGGLIPLTAGLDGLFSTLPNFSILVKIAALVLMLAGFALGSYALVENRFFSGMVRIQTDRGHKVISSGPYAWIRHPGYTGALVSYIAAPVLLDAVWAFIPAILLSIVLVIRTHLEDETLQDRLVGYREYAEQVRFRLFPGIW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XCE3</accession>
    <name>A0A0P6XCE3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Alpha-glucan phosphorylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_01960</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[(1-&gt;4)-alpha-D-glucosyl](n) + phosphate = [(1-&gt;4)-alpha-D-glucosyl](n-1) + alpha-D-glucose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:41732"/>
            <dbReference type="Rhea" id="RHEA-COMP:9584"/>
            <dbReference type="Rhea" id="RHEA-COMP:9586"/>
            <dbReference type="ChEBI" id="CHEBI:15444"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="2.4.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycogen phosphorylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000007">
        <property type="protein sequence ID" value="KPL80060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061283.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000007.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01960"/>
    <dbReference type="EnsemblBacteria" id="KPL80060">
        <property type="protein sequence ID" value="KPL80060"/>
        <property type="gene ID" value="ADN00_01960"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2318"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008184">
        <property type="term" value="F:glycogen phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011834">
        <property type="entry name" value="Agluc_phsphrylas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000811">
        <property type="entry name" value="Glyco_trans_35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024517">
        <property type="entry name" value="Glycogen_phosphorylase_DUF3417"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11897">
        <property type="entry name" value="DUF3417"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00343">
        <property type="entry name" value="Phosphorylase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000460">
        <property type="entry name" value="Pprylas_GlgP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02094">
        <property type="entry name" value="more_P_ylases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3417" evidence="5">
        <location>
            <begin position="14"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="4">
        <location>
            <position position="607"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000460-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF11897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL80060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="717" mass="83227" checksum="E313A5A7916E8A0A" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XCU8</accession>
    <name>A0A0P6XCU8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_07815</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000020">
        <property type="protein sequence ID" value="KPL78075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062430.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000020.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78075">
        <property type="protein sequence ID" value="KPL78075"/>
        <property type="gene ID" value="ADN00_07815"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="117" mass="12554" checksum="145E2E846B14AA06" modified="2016-01-20" version="1">MKESMKKQSWKLIPKTASGRWSVVLIVAMPILFSIGSSFAKGLYQSVPAGDSILADISARPALAFTMLAGMAAGISAFITGLLAILRQKEKALLVYVATVIGALFLFFLAGEFMFPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XCY8</accession>
    <name>A0A0P6XCY8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">dNK domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_01590</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061209.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01590"/>
    <dbReference type="EnsemblBacteria" id="KPL80563">
        <property type="protein sequence ID" value="KPL80563"/>
        <property type="gene ID" value="ADN00_01590"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1077"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019136">
        <property type="term" value="F:deoxynucleoside kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01673">
        <property type="entry name" value="dNK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002624">
        <property type="entry name" value="DCK/DGK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031314">
        <property type="entry name" value="DNK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01712">
        <property type="entry name" value="dNK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000705">
        <property type="entry name" value="DNK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="dNK" evidence="3">
        <location>
            <begin position="3"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="7"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="43"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="77"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="134"/>
            <end position="138"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000705-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000705-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL80563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="217" mass="25331" checksum="0B12C4EA43D72AE7" modified="2016-01-20" version="1">MYFVIEGVIGVGKTTLARLLQPSFEANLLLEVFEENPFLNDFYSDRARYAFQTQIFFLLSRYHQQNKGVPALMEQGRHIIGDYTFDKDSLFARINLHGDELEMYYRVHEALGEKITPPDLVVYLRASTRTLMQRIALRDRPYERQMERDYIADLNQAYEDYFVHQAEKLSIPVLAIDTNDIDFVRNPEDLSAIENRIRQVLHLPPFQPELPLVGDAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDE5</accession>
    <name>A0A0P6XDE5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_07305</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062324.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78267">
        <property type="protein sequence ID" value="KPL78267"/>
        <property type="gene ID" value="ADN00_07305"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="507"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="109"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="169"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="265"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="355"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="302"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="362"/>
            <end position="386"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="667" mass="74498" checksum="60CE995005A4A492" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDR7</accession>
    <name>A0A0P6XDR7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Gamma-glutamyl phosphate reductase</fullName>
            <shortName evidence="8">GPR</shortName>
            <ecNumber evidence="8">1.2.1.41</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Glutamate-5-semialdehyde dehydrogenase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Glutamyl-gamma-semialdehyde dehydrogenase</fullName>
            <shortName evidence="8">GSA dehydrogenase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">proA</name>
        <name evidence="10" type="ORF">ADN00_00415</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the NADPH-dependent reduction of L-glutamate 5-phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>L-glutamate 5-semialdehyde + NADP(+) + phosphate = H(+) + L-glutamyl 5-phosphate + NADPH</text>
            <dbReference type="Rhea" id="RHEA:19541"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58066"/>
            <dbReference type="ChEBI" id="CHEBI:58274"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.2.1.41"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 8">Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the gamma-glutamyl phosphate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.41" evidence="8"/>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060978.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00415"/>
    <dbReference type="EnsemblBacteria" id="KPL81038">
        <property type="protein sequence ID" value="KPL81038"/>
        <property type="gene ID" value="ADN00_00415"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3476"/>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004350">
        <property type="term" value="F:glutamate-5-semialdehyde dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd07079">
        <property type="entry name" value="ALDH_F18-19_ProA-GPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.309.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.605.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00412">
        <property type="entry name" value="ProA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016161">
        <property type="entry name" value="Ald_DH/histidinol_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016163">
        <property type="entry name" value="Ald_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016162">
        <property type="entry name" value="Ald_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015590">
        <property type="entry name" value="Aldehyde_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020593">
        <property type="entry name" value="G-glutamylP_reductase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012134">
        <property type="entry name" value="Glu-5-SA_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000965">
        <property type="entry name" value="GPR_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00171">
        <property type="entry name" value="Aldedh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000151">
        <property type="entry name" value="GPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53720">
        <property type="entry name" value="SSF53720"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00407">
        <property type="entry name" value="proA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01223">
        <property type="entry name" value="PROA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="3 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0521">NADP</keyword>
    <keyword evidence="7 8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5 8" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldedh" evidence="9">
        <location>
            <begin position="5"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL81038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="418" mass="45558" checksum="623885A8722D3DE7" modified="2016-01-20" version="1">MLIEMAKKAKAASKLLALSETAAKNSFLTGLADALWEGREELLKANSEDVNHARADGLTNALIDRLTVDEDRLKGIIADLTNVLHAEDPIGKVFEKSVQPSGLNLYKQRVPLGVIAVIYESRPNVTVDVASLAIKSGNAVILRGGKETLRTNQVFVSIIHKAMLQAGLPEDAVQFIDQPDRALVFELLKLHQYVDMVIPRGGAQLHQICRENSTIPVITGGIGICHLFVDESANLPASIDVIRNAKIQRPSVCNALDTVLIHERIAQKFLPDLIHQLCQDGVIFHVDSILMDRCGLVETSNVLRASQSDFDIEWLSLNLSIKSVGSLDEAVAHIQAHSTAHSDGILTENASHADRFVKTIDSSVVYVNASTRFTDGAQLGLGSEVAVSTQRLHARGPMGLEELTTYKWVASGDYLTRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDU3</accession>
    <name>A0A0P6XDU3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF126 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_00720</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061032.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00720"/>
    <dbReference type="EnsemblBacteria" id="KPL81084">
        <property type="protein sequence ID" value="KPL81084"/>
        <property type="gene ID" value="ADN00_00720"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3542"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002840">
        <property type="entry name" value="AcnX_swivel_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01989">
        <property type="entry name" value="DUF126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF126" evidence="1">
        <location>
            <begin position="49"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL81084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="148" mass="15970" checksum="18EF19DB5BBF6BE3" modified="2016-01-20" version="1">MTERIFKGRPVLSGACQGEALVSRQGFNTLASFQKSVILRSKKAICSDQNNSDLFQKEMTGKILCIPQTIGSTTGGLVLQTIARLGNGPKAILFSEHIDSLAAAGVILADIWDNHRFIVVDQLGQEFLHSVQQGQTITIAEDGTVTVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XG45</accession>
    <name>A0A0P6XG45_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_18355</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064503.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18355"/>
    <dbReference type="EnsemblBacteria" id="KPL70027">
        <property type="protein sequence ID" value="KPL70027"/>
        <property type="gene ID" value="ADN00_18355"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2978"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06533">
        <property type="entry name" value="Glyco_transf_WecG_TagA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004629">
        <property type="entry name" value="WecG_TagA_CpsF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34136">
        <property type="entry name" value="PTHR34136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03808">
        <property type="entry name" value="Glyco_tran_WecG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00696">
        <property type="entry name" value="wecG_tagA_cpsF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="262" mass="29554" checksum="2E63E5BF309D81A6" modified="2016-01-20" version="1">MGVKKPSESPPLFPRHNILGVAISAINMQDALTTIRGWVEREEPNYVCVTPAHAVMECVKDGGLRPVYNQAGLVTPDGMAIVWLLKLAGFSRVNRVYGPDLLRAVCAESLSRGWRHYFFGGAPQVTERLVARLRGGFPGLQVAGWDCPAFEGFDAAQEAAAIERIRESKADIVWVALGSPRQERWMAENYRRCGGVLVGVGAAFDFLSGNKPQAPRWMQRAGLEWLFRLASEPRRLWRRYLQYPRFVWLVFLQRLGLRKFPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XG87</accession>
    <name>A0A0P6XG87_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_18785</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064575.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70091">
        <property type="protein sequence ID" value="KPL70091"/>
        <property type="gene ID" value="ADN00_18785"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3067"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="96" mass="11109" checksum="3D713E0A2DA6D62D" modified="2016-01-20" version="1">MNNPTTTDQFVTIPTVLGEVELSEINYRMGGPSRAQQCRNMLEILKPQKATIFEMRDKKEAEDYRSMLYTMAILKFSESGRIGTRIVDNLLYVWLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGL8</accession>
    <name>A0A0P6XGL8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">CRISPR-associated endonuclease Cas1</fullName>
            <ecNumber evidence="8">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">cas1</name>
        <name evidence="9" type="ORF">ADN00_06160</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer, forms a heterotetramer with a Cas2 homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the CRISPR-associated endonuclease Cas1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="8"/>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062175.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06160"/>
    <dbReference type="EnsemblBacteria" id="KPL78883">
        <property type="protein sequence ID" value="KPL78883"/>
        <property type="gene ID" value="ADN00_06160"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1733"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004520">
        <property type="term" value="F:endodeoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043571">
        <property type="term" value="P:maintenance of CRISPR repeat elements"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09721">
        <property type="entry name" value="Cas1_I-C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.100.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01470">
        <property type="entry name" value="Cas1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002729">
        <property type="entry name" value="CRISPR-assoc_Cas1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042206">
        <property type="entry name" value="CRISPR-assoc_Cas1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019856">
        <property type="entry name" value="CRISPR-assoc_Cas1_DVULG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042211">
        <property type="entry name" value="CRISPR-assoc_Cas1_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01867">
        <property type="entry name" value="Cas_Cas1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00287">
        <property type="entry name" value="cas1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03640">
        <property type="entry name" value="cas1_DVULG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="7 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 8" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="2 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 8" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="8">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="249"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL78883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="343" mass="38608" checksum="508E4F1C3F9891B7" modified="2016-01-20" version="1">MKQLANVLYITSADAYLSLDGENIVIKKEEHVSTRLPLHNLENVVCFNYLGVSPALMGACSERNIGLCFLTPNGRFLARVSGKVKGNVLLRKKQYQVSEREAESVPIAASFLLGKIYNSRKVLERALRDHAMLVDVDALTKASSFLKQTLAVIPECNTVSELMAFEGSAAKIYFGVFDHLILQQHEDFSFRERSRRPPLDNMNSLLSFLYTLLTNETVSALDAVGLDPYVGFLHADRPGRPSLALDLMEEMRPLFADRLALTLVNRKQISGKGFTQKESGGILMDDDTRKAVLGAWQDRKKEEIVHPYLKERIPFGLILHVQAMLLARYLRGDLDAYPPFFWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGQ4</accession>
    <name>A0A0P6XGQ4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_03030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000014">
        <property type="protein sequence ID" value="KPL79318.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061484.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000014.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79318">
        <property type="protein sequence ID" value="KPL79318"/>
        <property type="gene ID" value="ADN00_03030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="135"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="187"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="229"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="294"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="321"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="377"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79318.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="536" mass="60385" checksum="26AC4C952AD0B5DA" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XIL4</accession>
    <name>A0A0P6XIL4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidyl-prolyl cis-trans isomerase</fullName>
            <ecNumber evidence="4">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_13295</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 3 4">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the FKBP-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="4"/>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063509.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000031.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74816">
        <property type="protein sequence ID" value="KPL74816"/>
        <property type="gene ID" value="ADN00_13295"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1141"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="5">
        <location>
            <begin position="11"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL74816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="170" mass="18034" checksum="6772AD2BA279FB98" modified="2016-01-20" version="1">MNESAVVVANDMVVTLDYTLTVDGEIVDTGSLDYLQGHQNIVPGLENRLLGMAEGEVKEVLVPAAEGYGEIDPEAFATVEKDKFPADFPFELGRELRVANTYGQVMLARICEIAEDSVRLDLNHPLAGKDLLFYAKIAGLRVATDEEMANGRLGGGCSSCSGGSCSSGCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XIX5</accession>
    <name>A0A0P6XIX5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_12905</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063431.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000027.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL75535">
        <property type="protein sequence ID" value="KPL75535"/>
        <property type="gene ID" value="ADN00_12905"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL75535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="180" mass="20686" checksum="6F7939FC86FEEC38" modified="2016-01-20" version="1">MDFQMSRLRIPVPPASILERAVGYQNHHTPKVGRSHARYLALWWEPCGDEVMVSDGIVSFTGHWPGYLTYIQHPLVAPALFNYNLGSSEDFATYHLLIDLDTHQAFVVLVPEAERILSLQWEQQPRNPLVTLFMEDLEPLLREWARNLQADVSMEAVMSRMAEDQKAVDTLRAWMDAQIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKN0</accession>
    <name>A0A0P6XKN0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Proton_antipo_M domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_16400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16400"/>
    <dbReference type="EnsemblBacteria" id="KPL72120">
        <property type="protein sequence ID" value="KPL72120"/>
        <property type="gene ID" value="ADN00_16400"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3722"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008137">
        <property type="term" value="F:NADH dehydrogenase (ubiquinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042773">
        <property type="term" value="P:ATP synthesis coupled electron transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003918">
        <property type="entry name" value="NADH_UbQ_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001750">
        <property type="entry name" value="ND/Mrp_mem"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00361">
        <property type="entry name" value="Proton_antipo_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01437">
        <property type="entry name" value="NUOXDRDTASE4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="24"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="51"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="75"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="111"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="214"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="271"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="306"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="354"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_M" evidence="3">
        <location>
            <begin position="72"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL72120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="378" mass="39665" checksum="A6F601D86EF1655F" modified="2016-01-20" version="1">MAFSAVSVVILAAAEYYAKLIPQGKRFGVISLISAGLILTGVWMPSELVRIILLSAAGLLLVCLIWPQNQLAGRWFLAASATGSLLVAGGLALSGMFSGALIEPAGIISKVVVCLVFIGYAVKLALLPFSLWLVSISENCSVMSAVLVVSLLDMAEFGELAALRVEVPWMFEQTLGVWIGLDVLCMLGGALLALAQTNVRRMLAYSTIDDMGYLILGLAAGSAGGVMGALVGALSHALCKFLLFGALGIAEHDLGHPLTTSDRGVSNRQPAASAAFIAGSLGMVGVPPLLGFIGRWRLYLGGMEMGGVWLAVLMASATTLALLYYVRIIHKVWLGQITEGPVTAPKRFRALEGILIGFIFLLVIGGFSPTIFAVLGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XLM5</accession>
    <name>A0A0P6XLM5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cys-tRNA(Pro)/Cys-tRNA(Cys) deacylase</fullName>
            <ecNumber evidence="3">4.2.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_11895</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the prolyl-tRNA editing family. YbaK/EbsC subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.-.-" evidence="3"/>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063236.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11895"/>
    <dbReference type="EnsemblBacteria" id="KPL76051">
        <property type="protein sequence ID" value="KPL76051"/>
        <property type="gene ID" value="ADN00_11895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.960.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004369">
        <property type="entry name" value="Prolyl-tRNA_editing_YbaK/EbsC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036754">
        <property type="entry name" value="YbaK/aa-tRNA-synt-asso_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007214">
        <property type="entry name" value="YbaK/aa-tRNA-synth-assoc-dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04073">
        <property type="entry name" value="tRNA_edit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006181">
        <property type="entry name" value="EbsC_YbaK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55826">
        <property type="entry name" value="SSF55826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA_edit" evidence="4">
        <location>
            <begin position="31"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR006181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL76051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="161" mass="17213" checksum="FD9458E848C331BB" modified="2016-01-20" version="1">MPVNNVTRLLDSRKIPYQAFELPAEKLGALETARQLNVPPEQVFKTIVILRPKPSKPLLAMVPGGYEVDLKKVAAALNEKKVSLPTQAEAEKLTGLQAGGISPLALLNKGFQVLLDSSASSFLEIHISGGQRGLNVRLPVAALVELTKARQADISIPSQSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XLZ4</accession>
    <name>A0A0P6XLZ4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glutamine amidotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_09520</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C56 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062755.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09520"/>
    <dbReference type="EnsemblBacteria" id="KPL77345">
        <property type="protein sequence ID" value="KPL77345"/>
        <property type="gene ID" value="ADN00_09520"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4143"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006286">
        <property type="entry name" value="C56_PfpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002818">
        <property type="entry name" value="DJ-1/PfpI"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42733">
        <property type="entry name" value="PTHR42733"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01965">
        <property type="entry name" value="DJ-1_PfpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51276">
        <property type="entry name" value="PEPTIDASE_C56_PFPI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DJ-1_PfpI" evidence="2">
        <location>
            <begin position="6"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01965"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="176" mass="19313" checksum="3CBC560DE8C79C78" modified="2016-01-20" version="1">MSLKGKKILYLIGPGFEELEFYVPIMRLQEEHAEVVVAGEKAGKVYFGKHGNCLDGKADIGFDQVDTGQFDAVIVPGGWAPDKIRRDEHVKRILREMNAQKKIIGMICHAGLVGISAGIVKGHDSTGSEGIKDDLLNAGANWRDEPAFRSGNLVWGRVVADIPDFNRELVKALQES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XME2</accession>
    <name>A0A0P6XME2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_18790</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70092">
        <property type="protein sequence ID" value="KPL70092"/>
        <property type="gene ID" value="ADN00_18790"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="91" mass="9980" checksum="C93101C95A1EF657" modified="2016-01-20" version="1">MTKRLRWPNTAEHARQAALGDANRGLIALSTVIHGKCAGRSEEMRQVAIANDCLHRIRFELEAVGPGKEKTQAEGGSRGFLQEVAQATRKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XMG2</accession>
    <name>A0A0P6XMG2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Glutamate 5-kinase</fullName>
            <ecNumber evidence="8">2.7.2.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Gamma-glutamyl kinase</fullName>
            <shortName evidence="8">GK</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">proB</name>
        <name evidence="10" type="ORF">ADN00_00410</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>ATP + L-glutamate = ADP + L-glutamyl 5-phosphate</text>
            <dbReference type="Rhea" id="RHEA:14877"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58274"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.2.11"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="8">Amino-acid biosynthesis; L-proline biosynthesis; L-glutamate 5-semialdehyde from L-glutamate: step 1/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the glutamate 5-kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.2.11" evidence="8"/>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060977.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00410"/>
    <dbReference type="EnsemblBacteria" id="KPL81037">
        <property type="protein sequence ID" value="KPL81037"/>
        <property type="gene ID" value="ADN00_00410"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3475"/>
    <dbReference type="UniPathway" id="UPA00098">
        <property type="reaction ID" value="UER00359"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004349">
        <property type="term" value="F:glutamate 5-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055129">
        <property type="term" value="P:L-proline biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04242">
        <property type="entry name" value="AAK_G5K_ProB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1160.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00456">
        <property type="entry name" value="ProB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036393">
        <property type="entry name" value="AceGlu_kinase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001048">
        <property type="entry name" value="Asp/Glu/Uridylate_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041739">
        <property type="entry name" value="G5K_ProB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001057">
        <property type="entry name" value="Glu/AcGlu_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011529">
        <property type="entry name" value="Glu_5kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005715">
        <property type="entry name" value="Glu_5kinase/COase_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019797">
        <property type="entry name" value="Glutamate_5-kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002478">
        <property type="entry name" value="PUA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00696">
        <property type="entry name" value="AA_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01472">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000729">
        <property type="entry name" value="GK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00474">
        <property type="entry name" value="GLU5KINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00359">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53633">
        <property type="entry name" value="SSF53633"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01027">
        <property type="entry name" value="proB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00902">
        <property type="entry name" value="GLUTAMATE_5_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 8" id="KW-0641">Proline biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PUA" evidence="9">
        <location>
            <begin position="279"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="49"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="136"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="168"/>
            <end position="169"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="212"/>
            <end position="218"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL81037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="369" mass="39800" checksum="9DBDD728669C3F44" modified="2016-01-20" version="1">MSSKRIVIKLGTSTITAGSAKISYPGLIDLARQVSILRQMGYEVIIISSGAIAAGRQILAQKDLPRQIPAKQMLAAIGQSKLMGIYTQIFGMYDLIVGQVLLTKDDLLDRRRYLNARNTLNALLSYRVIPIINENDTVATEEIRFGDNDNLSALVTNVLEADLLVLLTDQDGLYTSDPRSDPQARMISEVATEHIPEDLWQAAGGSVSGLGTGGMHTKLSAADLARKSGATVFIANGNTPDIIIKIVNGAARGTKFLPSNSTLESRKRYMLAGVQASTGILYIDPGAEKAIKKGGSLLPVGLVKIAGSFERGDIVRVRSAKLQEIAIGITNYSSDDLERIQGKNSTLIEDIVGYSYGDEVIHHNNMMLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XMZ9</accession>
    <name>A0A0P6XMZ9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 11 12">Uridine kinase</fullName>
            <ecNumber evidence="7 11 12">2.7.1.48</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="11">Cytidine monophosphokinase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Uridine monophosphokinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="primary">udk</name>
        <name evidence="14" type="ORF">ADN00_07955</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 12">
            <text>ATP + cytidine = ADP + CMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:24674"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17562"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.48"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 11 12">
            <text>ATP + uridine = ADP + H(+) + UMP</text>
            <dbReference type="Rhea" id="RHEA:16825"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16704"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.48"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5 11 12">Pyrimidine metabolism; CTP biosynthesis via salvage pathway; CTP from cytidine: step 1/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 11 12">Pyrimidine metabolism; UMP biosynthesis via salvage pathway; UMP from uridine: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 11 12">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 11 12">Belongs to the uridine kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.48" evidence="7 11 12"/>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77812.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062456.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07955"/>
    <dbReference type="EnsemblBacteria" id="KPL77812">
        <property type="protein sequence ID" value="KPL77812"/>
        <property type="gene ID" value="ADN00_07955"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.591"/>
    <dbReference type="UniPathway" id="UPA00574">
        <property type="reaction ID" value="UER00637"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00579">
        <property type="reaction ID" value="UER00640"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004849">
        <property type="term" value="F:uridine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044211">
        <property type="term" value="P:CTP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044206">
        <property type="term" value="P:UMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd02023">
        <property type="entry name" value="UMPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00551">
        <property type="entry name" value="Uridine_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006083">
        <property type="entry name" value="PRK/URK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026008">
        <property type="entry name" value="Uridine_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000764">
        <property type="entry name" value="Uridine_kinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00485">
        <property type="entry name" value="PRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00235">
        <property type="entry name" value="udk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11 12" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 12" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11 12 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="10 11 12" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 11 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PRK" evidence="13">
        <location>
            <begin position="9"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="14"/>
            <end position="21"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00005408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00021478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KPL77812.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="207" mass="23404" checksum="B55A924A03CBF9FC" modified="2016-01-20" version="1">MNYSKTPLVVAIAGGSGSGKTTVANVVLQRVGPQRISFLPHDAYYRELTGLPPAQRALVNFDHPDSLETELLIDHIQQLKNWQAVDLPVYNFTTHSRTGETVRVEPKRVILVEGILIFAEPKLRELFDIKIFVDTDSDIRFIRRLQRDIAERGRTTESVVQQYLTTVRPMHLEFVEPSKRYADVIIPEGGLNAVALDMVIARIESLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XN60</accession>
    <name>A0A0P6XN60_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_08525</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062561.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77903">
        <property type="protein sequence ID" value="KPL77903"/>
        <property type="gene ID" value="ADN00_08525"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL77903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="184" mass="21093" checksum="F449378296D35F18" modified="2016-01-20" version="1">MNPEKVSFLPFHAINEFMLVDYRQSVVQDVFSHLDPVSAETRRELLRMVKELVQVPGFRNSSQAPLPLKVRGAVSVFQKSADFCGATLQAWSDIHADLREHVYQLLKGRSWEVLPAEANRAKLPGFLTVWPKEETYEVLENAFQEQVENASQYVDDDIRLMLVWVSGRLPYDLMTGEENQPAQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XN74</accession>
    <name>A0A0P6XN74_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">PspC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_08520</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77921.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062577.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77921">
        <property type="protein sequence ID" value="KPL77921"/>
        <property type="gene ID" value="ADN00_08520"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007168">
        <property type="entry name" value="Phageshock_PspC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04024">
        <property type="entry name" value="PspC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="15"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="39"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="domain" description="PspC" evidence="7">
        <location>
            <begin position="7"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL77921.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="64" mass="7265" checksum="0FF7009EACB92F42" modified="2016-01-20" version="1">MAESHALRRSRRNRVLAGVCGGFSEFFGINVFWFRLAFLILFIPGGLPGVIPYTVLWLVIPKEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XNS9</accession>
    <name>A0A0P6XNS9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphatidylglycerol--prolipoprotein diacylglyceryl transferase</fullName>
            <ecNumber evidence="2">2.5.1.145</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">lgt</name>
        <name evidence="3" type="ORF">ADN00_07070</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the transfer of the diacylglyceryl group from phosphatidylglycerol to the sulfhydryl group of the N-terminal cysteine of a prolipoprotein, the first step in the formation of mature lipoproteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol) + L-cysteinyl-[prolipoprotein] = H(+) + S-1,2-diacyl-sn-glyceryl-L-cysteinyl-[prolipoprotein] + sn-glycerol 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:56712"/>
            <dbReference type="Rhea" id="RHEA-COMP:14679"/>
            <dbReference type="Rhea" id="RHEA-COMP:14680"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:57685"/>
            <dbReference type="ChEBI" id="CHEBI:64716"/>
            <dbReference type="ChEBI" id="CHEBI:140658"/>
            <dbReference type="EC" id="2.5.1.145"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein modification; lipoprotein biosynthesis (diacylglyceryl transfer).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the Lgt family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.145" evidence="2"/>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78232.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062282.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07070"/>
    <dbReference type="EnsemblBacteria" id="KPL78232">
        <property type="protein sequence ID" value="KPL78232"/>
        <property type="gene ID" value="ADN00_07070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3232"/>
    <dbReference type="UniPathway" id="UPA00664"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008961">
        <property type="term" value="F:phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042158">
        <property type="term" value="P:lipoprotein biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01147">
        <property type="entry name" value="Lgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001640">
        <property type="entry name" value="Lgt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30589">
        <property type="entry name" value="PTHR30589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01790">
        <property type="entry name" value="LGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00544">
        <property type="entry name" value="lgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01311">
        <property type="entry name" value="LGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="44"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="92"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="241"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>1,2-diacyl-sn-glycero-3-phospho-(1'-sn-glycerol)</name>
            <dbReference type="ChEBI" id="CHEBI:64716"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78232.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="283" mass="31514" checksum="4D3A53219C5F31EC" modified="2016-01-20" version="1">MVREGFSIGPLFVHWYGVIIMFGTVLAAFMAEREAKKRNMDSEFIWDALPYILITGIIGARLWHVFTPPDSMQAAGLTTSYYFQNPIEILKIWRGGLGIPGAVMGGMVAVYVYCKRHNIRFGDFGDIVAPGLALAQAIGRWGNFVNQELYGAPSNLPWAISIDEAHRLPEYMDVARYHPLFLYEFLWNLMNMGLLLWIGKKFAGRLKPGDILLTYLIVYPVGRFLLEYLRLDASSIGTINANQTLMAVVALGSALALFLRHRLGGKTSAEKSGGSEEESQAEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XNU5</accession>
    <name>A0A0P6XNU5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_14485</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000034">
        <property type="protein sequence ID" value="KPL73766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14485"/>
    <dbReference type="EnsemblBacteria" id="KPL73766">
        <property type="protein sequence ID" value="KPL73766"/>
        <property type="gene ID" value="ADN00_14485"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL73766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="455" mass="50202" checksum="03E93199732057DA" modified="2016-01-20" version="1">MPVLLAVLAGMLALVWGVGYVSTRYTTWLPAPYRKAAQVAPTKGSREKKWIADIDYYATQLPRLHINAFHSLSAEQFAQEIESLKASVPQLSDNQIGLELVRLTAAIGDAHTRAVPAQWRQASLLPLRLYWFDDGLVVTGVMPQSQEALGARLVSVEDTPLDEVVERLEPYISSENEMSLRSNIANLLLTADVLEALGLAESAQQVRLGFERADGTPFELSLAAVSAEEYREGIDNGMSGQEKPLYLSKTDQVYWFEFLPDTNTLFFQYNSCVDSPERPMQTFANELFAALDANPVERLVIDLRFNGGGNSAVLDPLIERLSQHPISQEGRMFVLISRNTFSSAILNALDLQSMAGATLVGEPTADRPDHFGEVRSFTLPNSGLLVTYSTKFFSIARGEANDQGDNMARMGIWLADNPPDDSGIRSLQPDVAVPFTSQDYFGLRDPLLEAVIQLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XPS3</accession>
    <name>A0A0P6XPS3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_08950</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77257.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77257">
        <property type="protein sequence ID" value="KPL77257"/>
        <property type="gene ID" value="ADN00_08950"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL77257.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="418" mass="48470" checksum="E20CC5176D32AF31" modified="2016-01-20" version="1">MSSKSALAEVKEMGKKIVPAPIRRFFWRAKEFILDHTEFTEKLLGIWKEALFQAEFVRNPSLRTFLLRTIRFSGDLVLVLRDFPMTKAYSLEGQTTRVVFVGREVEEFTHLFFSGDLVKREEPISVWSWQLPKKTKEWLAGGVDMVVHGVSRFFPWRAKAAFQATTPKWISQYFPIPDNCDEPPAGPKMRTLRKIYRDHAGCIGFRYSEQVSDFDVFYHRMYRPYVSNRHGSFVYVEPYEYLYKWFKKGGLILVNCKDELVSAMLVVKNGKWVYAAEAGVMDGNPELHAAGFPRVSVWSTAQWGNSQGCRKFQMGGTYSFRSNGVFQYKTFWNTIVTDFYGFIRNQWQFYLEQPGPALLNDLNEWGIIHEHRHQFYGVVFEGAQEPDAVEIARNLKTAHQDGLAGILRVSPGKMEYLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XPT4</accession>
    <name>A0A0P6XPT4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05415</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061955.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78689">
        <property type="protein sequence ID" value="KPL78689"/>
        <property type="gene ID" value="ADN00_05415"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="392" mass="44550" checksum="4CCF8BAC289B6D69" modified="2016-01-20" version="1">MATSKRKRFSAFDDFQAPQDEPLPAPDPSNVSSLFSSQLRVEPVQQVERIERLKPSQMLPDRFQPRRLLPAALRDAFFAGELDCYETAAEWFTLSRQDAGHRTIVDRLLAMGSSFEEHGQIKPITGSWVPAEDGSYIFLIETGERRFWAACLQMIKEQRKDEPLLRVEVVEKPTRQRQVLENRHAENPSAVSQACEVASLILAELGKNPDGSYTDEYEYFRQARAQRMPAGLWDQIKPIMQLTRPRMVQLLNILQFPSTLLDMADRYRLPERVLREVLAFPPEQWEEMLKVSIQNELTSDEVSALAENDQARPGQAQAARPAKNAKGKTSPGKIATSGIRRFSNALVELDRMLQEEVMDQVADDLAASEEASDTLTFLEELVALIRVRIHSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQF6</accession>
    <name>A0A0P6XQF6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Aspartate carbamoyltransferase</fullName>
            <ecNumber evidence="3">2.1.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_03665</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>carbamoyl phosphate + L-aspartate = H(+) + N-carbamoyl-L-aspartate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20013"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:32814"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="EC" id="2.1.3.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the aspartate/ornithine carbamoyltransferase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.2" evidence="3"/>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061610.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03665"/>
    <dbReference type="EnsemblBacteria" id="KPL79000">
        <property type="protein sequence ID" value="KPL79000"/>
        <property type="gene ID" value="ADN00_03665"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.85"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00116"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016597">
        <property type="term" value="F:amino acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004070">
        <property type="term" value="F:aspartate carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1370">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006132">
        <property type="entry name" value="Asp/Orn_carbamoyltranf_P-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006130">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036901">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002082">
        <property type="entry name" value="Asp_carbamoyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006131">
        <property type="entry name" value="Asp_carbamoyltransf_Asp/Orn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11405:SF16">
        <property type="entry name" value="PTHR11405:SF16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00185">
        <property type="entry name" value="OTCace"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02729">
        <property type="entry name" value="OTCace_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00100">
        <property type="entry name" value="AOTCASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53671">
        <property type="entry name" value="SSF53671"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00670">
        <property type="entry name" value="asp_carb_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="OTCace_N" evidence="8">
        <location>
            <begin position="7"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="OTCace" evidence="7">
        <location>
            <begin position="157"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL79000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="316" mass="35826" checksum="7E04AA36952D77B3" modified="2016-01-20" version="1">MRSFLGRDILSLKEFERNEFFHIFEVADEMAPIAKSRQNSDMLKDKTMVTAFYQPSTRTRLAHEAAMHRLGGHVTGFSDAKMTRAGDWYQESIKDTVKMLEFYGDVIVMRHFQQGAPQEAAKWASVPIINGGDGWGEHPTQILTDLYTVLTEKGRLDGLKWLAVGDMRMRTMHSLGYALSQFDCPVTFVAPPDMSLTDEFKAELKQYCVDFKEAEHVEQAIADADVILVEPVVQPDYTKARQEAGEHGMTPANYKITRELLSTKAKSDAILLHSLPRMDEIPPDVDITRWSRYWQEAFNGVVMRMALLGLVLGAME</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQJ2</accession>
    <name>A0A0P6XQJ2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">4-vinyl reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_04010</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061674.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04010"/>
    <dbReference type="EnsemblBacteria" id="KPL79055">
        <property type="protein sequence ID" value="KPL79055"/>
        <property type="gene ID" value="ADN00_04010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024096">
        <property type="entry name" value="NO_sig/Golgi_transp_ligand-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004096">
        <property type="entry name" value="V4R"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02830">
        <property type="entry name" value="V4R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00989">
        <property type="entry name" value="V4R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111126">
        <property type="entry name" value="SSF111126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="V4R" evidence="1">
        <location>
            <begin position="144"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="210" mass="22922" checksum="0591969BB65BC6A0" modified="2016-01-20" version="1">MEPIPKSGLYYPNKIPRILLMALEDVMGKNGVNAILNLAQLQHLIGNYPPDNLNREFDFADFSAINGALEEMYGPRGGRGLALRAGRAAFAEGLRNFGALAGAGDLAFKVLKLEAKLRIGLPAMAKVFTTTSDQLSTVQEFEDHYLYTIHRCPVCWGRTVDKPACFMAVGLLQEGLKWVSGGNEFRVSQSACHAAGDEVCNFVVFKEPIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XR41</accession>
    <name>A0A0P6XR41_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_13255</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063501.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000031.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13255"/>
    <dbReference type="EnsemblBacteria" id="KPL74808">
        <property type="protein sequence ID" value="KPL74808"/>
        <property type="gene ID" value="ADN00_13255"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.90.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035328">
        <property type="entry name" value="DUF3048_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021416">
        <property type="entry name" value="DUF3048_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023158">
        <property type="entry name" value="YerB-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11258">
        <property type="entry name" value="DUF3048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17479">
        <property type="entry name" value="DUF3048_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159774">
        <property type="entry name" value="SSF159774"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133186" evidence="1">
        <location>
            <begin position="29"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3048" evidence="2">
        <location>
            <begin position="90"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3048_C" evidence="3">
        <location>
            <begin position="262"/>
            <end position="382"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL74808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="407" mass="45401" checksum="C5480D305EE5F4E0" modified="2016-01-20" version="1">MNNNKIKPLIFFCVLLIAAGCTTGPNSAVDAGQTGLSQDLFASAEAPAAVENTPFVVAVPPASAEEEETTFTYPPEGVGPESYPQGINPLTGLPPAQASLLNRRPVIVKVENMPRERSRPQWGLPQADLVFEYYIEYGDTRFSVVYYGQQPEQVGPIRSARHVDKQLIQMYRSFFVFGGAYPELYDEMVQADYGDRIIREGPNTSPALFRFEPDQNNELMVNLGLLEEVYATYGMDNSRQPLQGLAFNPVAPQGGQPASRVYARFSGAVYNRWDYDPQSGTYLRFADAQNDVNNVEEVYAPLMDAASGQQVAMENVVIILTRYYQLNGAEVYDIPLQGNGPAFVARDGQIYAARWERADQEMPLRLMLDNGKAFPLKPGRTWFELMGESTQQSVVEEAGWRFVLRMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XRL4</accession>
    <name>A0A0P6XRL4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Hydantoin utilization protein A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_15405</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SIMIBI class G3E GTPase family. HypB/HupM subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064014.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15405"/>
    <dbReference type="EnsemblBacteria" id="KPL72295">
        <property type="protein sequence ID" value="KPL72295"/>
        <property type="gene ID" value="ADN00_15405"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.783"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051604">
        <property type="term" value="P:protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003495">
        <property type="entry name" value="CobW/HypB/UreG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004392">
        <property type="entry name" value="Hyd_mat_HypB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30134">
        <property type="entry name" value="PTHR30134"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02492">
        <property type="entry name" value="cobW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00073">
        <property type="entry name" value="hypB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="cobW" evidence="2">
        <location>
            <begin position="22"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL72295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="208" mass="22583" checksum="0C1916F9B2C75450" modified="2016-01-20" version="1">MDANDQVASVNQKMLDDHNIFAINIMAAPGSGKTSVILKTIEALRGKLRIGVIEGDTAPVTIDADKIMAAGMPAVQINTGGNCHLDAMMVKRGLEAMNLDEIDLLIIENVGNLICPAGFALGNHANVVVASIPEGDDKPYKYPNIYRGLDVLIINKTDLLPYINFNMDYFRQGVELLNPGLTTFEVSCQTGEGIQAWADWLLAKILNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUA4</accession>
    <name>A0A0P6XUA4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transketolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05610</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78720.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061990.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05610"/>
    <dbReference type="EnsemblBacteria" id="KPL78720">
        <property type="protein sequence ID" value="KPL78720"/>
        <property type="gene ID" value="ADN00_05610"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1599"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005475">
        <property type="entry name" value="Transketolase-like_Pyr-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02779">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00861">
        <property type="entry name" value="Transket_pyr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transket_pyr" evidence="1">
        <location>
            <begin position="9"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78720.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="321" mass="34192" checksum="785DDA678D16E415" modified="2016-01-20" version="1">MSAVLSSGKANLEVFADILLETGVQDRDLVVVTSDSRGSGKLTGFGKKLPAQMVEIGIAEQNLVGVAAGLAAAGKKTFAVSPACFLTARSLEQIKNDVAYSDQPVRLVGISAGVSYGALGTTHHSLHDLAVLQAINNITIVVPADNYETREAVRAAYEQNKPVYLRFGKKSMPALPHNPGDFEIGKGRVLREGDDVLFVATGEAVLPAFQAAEELELHGIMSTVISMHTVKPLDTDLLKTYADRCRAVITVEEHSIHGGLGSACASYLLQVGYHKPFHIVAIPDEPTVSGSQGEIFNHYGISAEGLSQLAMNMLVEKEQIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-12-02" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUD4</accession>
    <name>A0A0P6XUD4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ADN00_10420</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062938.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76984">
        <property type="protein sequence ID" value="KPL76984"/>
        <property type="gene ID" value="ADN00_10420"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019264">
        <property type="entry name" value="DUF2179"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044035">
        <property type="entry name" value="DUF5698"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022930">
        <property type="entry name" value="UPF0316"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40060">
        <property type="entry name" value="PTHR40060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10035">
        <property type="entry name" value="DUF2179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18955">
        <property type="entry name" value="DUF5698"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="64"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5698" evidence="9">
        <location>
            <begin position="25"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2179" evidence="8">
        <location>
            <begin position="117"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF10035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF18955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL76984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="184" mass="19960" checksum="3A6962C641F306E3" modified="2016-01-20" version="1">MMELNPIYAGILVFFLRVIDMSLDTLRLLFVMRGKKLLAGAVGSIQAAVFVVAIGAVLTGPLNVWTVLGYAGGFGTGVILGIYLEQRLAIGFGMLQVFSAERGAEIAARLREAGYAATISTATGMKGEVFIIHCAVQRKEIGRVQLLITQVDPDAFITLDDVQPLHSGYFKPSDRRKWGRSARV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUE1</accession>
    <name>A0A0P6XUE1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_10480</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062950.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10480"/>
    <dbReference type="EnsemblBacteria" id="KPL76993">
        <property type="protein sequence ID" value="KPL76993"/>
        <property type="gene ID" value="ADN00_10480"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004427">
        <property type="term" value="F:inorganic diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006796">
        <property type="term" value="P:phosphate-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036649">
        <property type="entry name" value="Pyrophosphatase_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50324">
        <property type="entry name" value="SSF50324"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="127" mass="14345" checksum="464B0F7B688D58B0" modified="2016-01-20" version="1">MQKADAFQFLGRRLRAVIDRPLGWQDARFKWAYPLNYGYIPGVFSADGEELDAYVLGPRQPLAEFDGVCAAVIERLDDVECKLVLVEPGARWSEAQIRREVDFIEQYFCSRLKMAPGLDGVGKDADS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUG2</accession>
    <name>A0A0P6XUG2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Sugar-bind domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_14865</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SorC transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000036">
        <property type="protein sequence ID" value="KPL73072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063820.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000036.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL73072">
        <property type="protein sequence ID" value="KPL73072"/>
        <property type="gene ID" value="ADN00_14865"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007324">
        <property type="entry name" value="Sugar-bd_dom_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04198">
        <property type="entry name" value="Sugar-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sugar-bind" evidence="2">
        <location>
            <begin position="67"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL73072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="330" mass="36269" checksum="9AF2787BADF34483" modified="2016-01-20" version="1">MAKLTTKEEMRLLSKVGKLYYEEGLTQNEIVDRLQLSRAKISRLLQAARDRGVVQIMVISPPGIYPDLEMQIETRYQLKEAIVVEVTEPESSESVSRELGVAAANYLQRIIREDETLGVSWGTTLSHMAASLQPNIFPEAQVVQLLGGLGAPESEVHATDICRRMARMLGCRLTLMPSPGIVDRQEIKDIILSDSHVQKAFDSFRDLSTVFLGIGAPNDQSVMLTSGTILTQKDLQELLECGAVGDIALRFFDKFGQPVRSELDSRVIGIGLDQLCKVDRVVGVAGGSHKVEAILGALRGKLVNVLITDQVTARRLLEPFGNFNGARGRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUI3</accession>
    <name>A0A0P6XUI3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH cro/C1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10115</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10115"/>
    <dbReference type="EnsemblBacteria" id="KPL77067">
        <property type="protein sequence ID" value="KPL77067"/>
        <property type="gene ID" value="ADN00_10115"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2486"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="22"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="208" mass="23174" checksum="F99DD3783BE22CB6" modified="2016-01-20" version="1">MQVMQSSVTSHEPAEINVGRRLQELRALRGLSIRSLAEISGLNFNTLSLIENEKSSPNVLTLQQLASALQVPITAFFEVSFLPKDFVFQKAGQRPRTSFPHGELEDMGGGLALGEATPLLMTSKPKTNSGADTIVHTGQEFVYCLEGSLVYWVGQQEYHLEPGDSLIFQAHIPHRWENRSNEINRCILVVCPSDQEDRSVGQHLMNEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XV95</accession>
    <name>A0A0P6XV95_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01385</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80527.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061171.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01385"/>
    <dbReference type="EnsemblBacteria" id="KPL80527">
        <property type="protein sequence ID" value="KPL80527"/>
        <property type="gene ID" value="ADN00_01385"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006675">
        <property type="entry name" value="HDIG_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00277">
        <property type="entry name" value="HDIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51831">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD" evidence="1">
        <location>
            <begin position="19"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80527.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="211" mass="23580" checksum="F00EE01FA1BB31AE" modified="2016-01-20" version="1">MPTLEQARQWYQSAESVHNFDHVLRVYRTAERLAQAENADLEIVRAAALLHDVADSAAGSQQRKEHHIASAEFAAGVLAEEGWPPERIAAVQHCIRAHRFRHNGDEPQTVEAKVLFDADKLDVLGAIGVVRVVAYATLAGQPIYAEPSARFLASGEKEPGEPHSAYHEHLFKLVKIKERLFTHAAKKLAEERDAYIRAFFERLIAESNGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XW81</accession>
    <name>A0A0P6XW81_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_08830</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000022">
        <property type="protein sequence ID" value="KPL77679.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062626.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000022.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77679">
        <property type="protein sequence ID" value="KPL77679"/>
        <property type="gene ID" value="ADN00_08830"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="SSF48239"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL77679.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="319" mass="35632" checksum="291288E62196FEB8" modified="2016-01-20" version="1">MDVILQQLLDSPEAALRYKARRFVLGEDPQSPAMLALQAEIAKSPAARALLSERAADGRIERPPYQKWRGAHWVLAQLADLYYPPGDRELIPLREQVAAWLPSLTPHVVLAGRERFCASIPANALFAMLRLGIATPFAEELVHLLMDGQWPDGGWNCDKRPAAHTSSLHESLIPLRALALYARHSGDPRARTCAERAAEFFLARRLFHRLSDGSVIAPQFIQLHYPYYWRYNFLLALVVMMEGGWLDDPHCADALDLLASKRLPDGGFAAETAYYRVRGSDDPLSGCTPMPWGGVRKNRSNPWVSVDALSVLRAAGRYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y0P6</accession>
    <name>A0A0P6Y0P6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Peptide permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_06380</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062127.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06380"/>
    <dbReference type="EnsemblBacteria" id="KPL78840">
        <property type="protein sequence ID" value="KPL78840"/>
        <property type="gene ID" value="ADN00_06380"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1779"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045621">
        <property type="entry name" value="BPD_transp_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19300">
        <property type="entry name" value="BPD_transp_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="97"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="130"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="241"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="293"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="95"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL78840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="320" mass="35686" checksum="289CA501BDEBEA2F" modified="2016-01-20" version="1">MRSYILKRLLQAIPILIGITLLTFMIMQLAPGNPMQTMINPRISPEELARAEQRLGLDKPLIVQYFNWLNEIFKGNLGYTVKTGQPVGKLIMERLPATLLLTGTAFILSFMIGIPLGVFSATHKYSPSDYVLTVFAFIGISIPSFFFGIALIYILGVKLSWLPTSGMVTINMAGTEFELFIDRVKHLIMPAFVLALPQMATVMRFTRSSMIEVMTHDYIRTARSKGLSNQAVRFKHALRNAAIPVITIFGLSIPFLFGGAYITETIFNWPGMGQLGISAITSREYPVIMGLNLFTSMLVLAGNLIADILYAFVDPRIRYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y0S1</accession>
    <name>A0A0P6Y0S1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">PMT_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ADN00_06450</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06450"/>
    <dbReference type="EnsemblBacteria" id="KPL78849">
        <property type="protein sequence ID" value="KPL78849"/>
        <property type="gene ID" value="ADN00_06450"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1793"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038731">
        <property type="entry name" value="RgtA/B/C-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13231">
        <property type="entry name" value="PMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="73"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="312"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="335"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="364"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="406"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="486"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="513"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="538"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="568"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="domain" description="PMT_2" evidence="9">
        <location>
            <begin position="283"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL78849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="741" mass="82286" checksum="A31FAFEE9435E147" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y4F0</accession>
    <name>A0A0P6Y4F0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_10940</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76483.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063050.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10940"/>
    <dbReference type="EnsemblBacteria" id="KPL76483">
        <property type="protein sequence ID" value="KPL76483"/>
        <property type="gene ID" value="ADN00_10940"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.90.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035328">
        <property type="entry name" value="DUF3048_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021416">
        <property type="entry name" value="DUF3048_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023158">
        <property type="entry name" value="YerB-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11258">
        <property type="entry name" value="DUF3048"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17479">
        <property type="entry name" value="DUF3048_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159774">
        <property type="entry name" value="SSF159774"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133377" evidence="2">
        <location>
            <begin position="24"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3048" evidence="3">
        <location>
            <begin position="59"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="DUF3048_C" evidence="4">
        <location>
            <begin position="250"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="50"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="126"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF11258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL76483.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="436" mass="47722" checksum="F11844C6DCFFF834" modified="2016-01-20" version="1">MKKKYWFVWSLLLVSLLFSTAAAPMPASGVGEGPAGEPQQDPPPTHPTGGSSPSAINPLTGLPVENPQNLDVPPALVSVTNWPPNARPQAGLSFSPMVFELYIGEGMSRFLAMFYGDFPTTITKEEGNSPVGPGSSSPTVQGAEAAVGPIRSGRLPYESLRSIYNGFLVMASAYKGVAANLSQHTNVFGSDNDDINSALIPVNQLETIAQSTQRQLGDAALSGMVFDAKAPAGGVKLDRLWFIYNAMDMILWQYDPAIESFRRYQDQADGKTFNQFTDRLNGESLTYENIILLYANHHGCTETAFDIDLMYINRAPALLLRDGKAYKIFWTTANGEYEKTTGKLRPIRFVDANGDPFPLKPGQTWVYLLPTGTQAWEAPNKEEIPVNTPQWVAPNAQALLYNLLNNKEAGSGNWVTRYYASMITYDKAVCDKITGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y5P8</accession>
    <name>A0A0P6Y5P8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hydrogenase expression/formation protein HypE</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_10075</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HypE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76931.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062874.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10075"/>
    <dbReference type="EnsemblBacteria" id="KPL76931">
        <property type="protein sequence ID" value="KPL76931"/>
        <property type="gene ID" value="ADN00_10075"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.650.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011854">
        <property type="entry name" value="HypE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010918">
        <property type="entry name" value="PurM-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036676">
        <property type="entry name" value="PurM-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016188">
        <property type="entry name" value="PurM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036921">
        <property type="entry name" value="PurM-like_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30303">
        <property type="entry name" value="PTHR30303"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00586">
        <property type="entry name" value="AIRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02769">
        <property type="entry name" value="AIRS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005644">
        <property type="entry name" value="Hdrgns_mtr_HypE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55326">
        <property type="entry name" value="SSF55326"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56042">
        <property type="entry name" value="SSF56042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AIRS" evidence="2">
        <location>
            <begin position="46"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="AIRS_C" evidence="3">
        <location>
            <begin position="151"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL76931.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="334" mass="36072" checksum="B4DCA91E9FBFF2DE" modified="2016-01-20" version="1">MSKFSLEVLERYVHPFIQNNDPDVILGSVFGEDVAITRVHEGVLVSHVDPIVGAVKDIGWLAVHVACNDIATSGTPPRWILVLVLVPRREDEHLLEEIMRDASRAAAELGVTIIGGHSGYSSNLARPLVAVTALGTITDLQPVQTRGARLGDHVLITKGVALEGTAILANDFSDTAIELGLNQADLEAARQLMKSVSIVPEALILAKHGATSMHDVTRGGLLETLLEMAKLSQVKILVEEGQISLSPIVERFAKAFDFNPLKMISSGTLAATVPPGQVEAASEQLRQAGISFSDIGQIVAGEGVQINHGETMRLYHDIHCEEDELARIWELYPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y6F6</accession>
    <name>A0A0P6Y6F6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">F420-0--gamma-glutamyl ligase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_00250</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060950.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00250"/>
    <dbReference type="EnsemblBacteria" id="KPL81016">
        <property type="protein sequence ID" value="KPL81016"/>
        <property type="gene ID" value="ADN00_00250"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3444"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043773">
        <property type="term" value="F:coenzyme F420-0 gamma-glutamyl ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008225">
        <property type="entry name" value="F420-0_g-glutamyl_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002847">
        <property type="entry name" value="F420-0_gamma-glut_ligase-dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01996">
        <property type="entry name" value="F420_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01916">
        <property type="entry name" value="F420_cofE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="1 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="4" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0464">Manganese</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0630">Potassium</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F420_ligase" evidence="8">
        <location>
            <begin position="11"/>
            <end position="232"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01996"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL81016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="256" mass="28115" checksum="C2B6E4440C96F56A" modified="2016-01-20" version="1">MPLTLTTLRNMPEIHPGDNLVELILEAMDADHVPVEDGDILVLAQKIVSKAEGRLVNLVDVEAGDQALQVAQVAQKDPRLVELILQESREVLRMRPGVIIVEHRNGFVCANAGIDHSNVRGEGKDPQLWYLLLPKDADQSAREFRAEVWRLIGVNVGVLIIDSHGRAWRNGTVGITIGLAGVPGIVDMRGMQDMYGYRLQNTLIAAADELAGAASLMMGQADEKSPVVIVKGFPYPLKESSSLKELIRSKDQDLFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y6L8</accession>
    <name>A0A0P6Y6L8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Pyrimidine reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_00635</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061016.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00635"/>
    <dbReference type="EnsemblBacteria" id="KPL81071">
        <property type="protein sequence ID" value="KPL81071"/>
        <property type="gene ID" value="ADN00_00635"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3522"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008703">
        <property type="term" value="F:5-amino-6-(5-phosphoribosylamino)uracil reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.430.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024072">
        <property type="entry name" value="DHFR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002734">
        <property type="entry name" value="RibDG_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01872">
        <property type="entry name" value="RibD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53597">
        <property type="entry name" value="SSF53597"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RibD_C" evidence="1">
        <location>
            <begin position="37"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL81071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="287" mass="32136" checksum="E4301DE1765EBE2D" modified="2016-01-20" version="1">MDELITQLYPLPSSERQLKGLYLSHNLRQYSHVSKKPFVYANFIVSLDGRIAVPHEDGNGQAVPTSIANERDWRLFQELATQSDLLISSGRYLRDWAAGRAQEILRVDDPRFSDLKGWRLDHNLPPQPDIAIISSSLEFPIPEVLTKSRRKVIVFTTNNPDLERVKEIEATAGKVFVAGDSSVSGEKMVQQMHELGYHTIYSAAGPKILHLLLKGGVLDRLYLTQTNRLLGGQPFSSIVEGDLFDAPIGVNLHTLYFDSHGLDGLGQLFMSYNLANQPIPKSEMNPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YAD9</accession>
    <name>A0A0P6YAD9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">CRISPR-associated exonuclease Cas4</fullName>
            <ecNumber evidence="6">3.1.12.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_06165</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA).</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="6">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="6">Mg(2+) or Mn(2+) required for ssDNA cleavage activity.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>iron-sulfur cluster</name>
            <dbReference type="ChEBI" id="CHEBI:30408"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the CRISPR-associated exonuclease Cas4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.12.1" evidence="6"/>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062089.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06165"/>
    <dbReference type="EnsemblBacteria" id="KPL78805">
        <property type="protein sequence ID" value="KPL78805"/>
        <property type="gene ID" value="ADN00_06165"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1734"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013343">
        <property type="entry name" value="CRISPR-assoc_prot_Cas4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022765">
        <property type="entry name" value="Dna2/Cas4_DUF83"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01930">
        <property type="entry name" value="Cas_Cas4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00372">
        <property type="entry name" value="cas4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0408">Iron</keyword>
    <keyword evidence="3 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5 6" id="KW-0464">Manganese</keyword>
    <keyword evidence="1 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cas_Cas4" evidence="7">
        <location>
            <begin position="13"/>
            <end position="202"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL78805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="222" mass="25385" checksum="75C3CC672AFEDF94" modified="2016-01-20" version="1">MKPEYTPDELLPLSGIQHFLFCRRQWALIHVERQWQENVLTVEGKLLHKRVDDPFFTETRSGTIIARSVPVASYILGFSGVCDVVEFTKSPQGVKLPGRQGLYLPVPVEYKRGKPKSDPVDEAQLCAQAICLEEMLAVSIPRGYLYYGETRHRVEVEMTTELRTLVKQMAVEMHAYFQRGYTPRVKTSRACQSCSLADICLPALQEKTMTASQYIRQQLEKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YBA3</accession>
    <name>A0A0P6YBA3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_05020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061858.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79207">
        <property type="protein sequence ID" value="KPL79207"/>
        <property type="gene ID" value="ADN00_05020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="192" mass="21192" checksum="ED8714DCDA95C704" modified="2016-01-20" version="1">MRKWIIIAALGAAILFAALLLLDFHLSISSTAQNISVSRISGGAGDAQNPNPLPPQTSPLRLYTPDPKLSQLLARQIKEAPGIDQIEIVSELPEHTGQAVLVVTLPEHNRLWLGFFATAETNAQMTFASDGQWQSNHIEMRDGQPPVVRVEACLALRDRSAGLMSRPWYLRHLREQIAEEVVKTLSEQLASQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YDG2</accession>
    <name>A0A0P6YDG2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000007">
        <property type="protein sequence ID" value="KPL80048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061271.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000007.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01900"/>
    <dbReference type="EnsemblBacteria" id="KPL80048">
        <property type="protein sequence ID" value="KPL80048"/>
        <property type="gene ID" value="ADN00_01900"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="141"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="195"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="322"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="356"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="379"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="411"/>
            <end position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="452" mass="49557" checksum="A6393BB4DFE13A72" modified="2016-01-20" version="1">MKQRLTDALKGLRQDRLLQGVIKNTGYLFSSSTVSMVLGMLQSIFAARLLGVELLGVLGTITSFASTINRLLSFRMSELVVKYLGRDLTEERRERAKGVVALAALTEASASVIAFGVLYWLAPLAAEFLAKDASFTPLFRIYGVSILAGLVVETATGILQIDNRFRAQAVINVAQSVLTAAMILAAFVLKGGLFWVMLAYLVGKVILGIGPVGLALGSLRRLFGPDWWRISAEHMPKLKEVMHFAVSTNLSATINLLVRDSELLWISYFLSPLEAGYYKIAMAVVNLVVMPITPFISTTYPEISRSVAAKQWQRLRHLLRRVTLFSGAWTLVTTLGLLVLGRWVIGLMYGVEYIPAYPALMVLLVGYGLANVFFWNRPLLLALGLPGFPVAAMLAGGLVKVGLAFPLVPRYGYVCEALLLTSFFIISVIPILWKGMRELRAAERQNPEGAAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YEM9</accession>
    <name>A0A0P6YEM9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_01525</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061197.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80551">
        <property type="protein sequence ID" value="KPL80551"/>
        <property type="gene ID" value="ADN00_01525"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="15"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="267"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="47"/>
            <end position="54"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL80551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="541" mass="59826" checksum="3EF3FF432A1227AE" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GL40</accession>
    <name>A0A0N8GL40_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_17245</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064294.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17245"/>
    <dbReference type="EnsemblBacteria" id="KPL71434">
        <property type="protein sequence ID" value="KPL71434"/>
        <property type="gene ID" value="ADN00_17245"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="5"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="161"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="161"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL71434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="265" mass="29805" checksum="F8DFB89ED6F187AA" modified="2016-01-20" version="1">MEKANVLIIEDDDIVARTIERLLRGAEFHTYVAGTGVDGLQLARRRVPDLVILDVIMPGMNGYEVCQEMRADPLLKDVPILFLTAKAKDEDRISGFKAGADDYLSKPFNMEELILRVRAILKRARGARAAEPENDKKPAGGFSALLNIFAKKEEEPPEQPPNTISACGYILNTQTFELDTPHIGKIRLTPVQFDLLYHLMCHPNEIFSPARLLDEVWNYPSNTGSPDLVRVHIKNLRERVEIDAKNPNFIKTVSGYGYTISTEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMB1</accession>
    <name>A0A0N8GMB1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13215</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063493.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000031.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74802">
        <property type="protein sequence ID" value="KPL74802"/>
        <property type="gene ID" value="ADN00_13215"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="170" mass="18567" checksum="C0AEE8DF875F0745" modified="2016-01-20" version="1">MIEIRPECSSDVTAIHLVNAAAFQQENEARLVDQLRDQGGLTLSMVCIQDDQIIGHIAYSPVVVEFDDGGSLQALALAPVAILPEHQNSGVGTHLIQVSLDILKAQGHHLVIVLGHPDYYPRFGFKPASGFNIRSPYPVPNEAFMLLELTAGTLENRPGVVRYRPEFDGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GN25</accession>
    <name>A0A0N8GN25_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_09965</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76914">
        <property type="protein sequence ID" value="KPL76914"/>
        <property type="gene ID" value="ADN00_09965"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="13"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="304"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="96"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL76914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="331" mass="34196" checksum="D1B949B8C0FD0C8A" modified="2016-01-20" version="1">MITMPWADILTDIFLTVALLLVVGGCGVLVSVLLRRVLQVKADREHALKLTNQGNCRSHYRLSIVQPHPELAFTFLSNHIPLAPIVEPVALPNAEEVERSSAQIDPTPAPQAAGKPALPQPPAIKPDGALKAGQNVAAKSGVAAGLLGTLGSLLPGKAGAGLKAQAGAARQVQAGASKAVQAPQAMQRKASALGQAGGRLGVQVPAPAGTSAAQASPAYAVKTSAPTAPAAGNKPLVVQTPALEPGESLLLTLRIGKTQKRYPSGSFHYTLESLPVPEDASLVSPDAVSRQGMVYFRPVGAWRYWLPGIASGLMLLGALLGILYGLVFIWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GN34</accession>
    <name>A0A0N8GN34_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76986">
        <property type="protein sequence ID" value="KPL76986"/>
        <property type="gene ID" value="ADN00_10430"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="10"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="68" mass="7942" checksum="B565CCC6A9F0335F" modified="2016-01-20" version="1">MNPVESAASPDKLSRRRQERFNRVDQNRDTDEEFELEEFGGVKRGKPAKRGHKTGKLRKPSFDDEFGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GN40</accession>
    <name>A0A0N8GN40_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aspartate racemase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10755</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the aspartate/glutamate racemases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062999.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10755"/>
    <dbReference type="EnsemblBacteria" id="KPL77034">
        <property type="protein sequence ID" value="KPL77034"/>
        <property type="gene ID" value="ADN00_10755"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2629"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047661">
        <property type="term" value="F:amino-acid racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015942">
        <property type="entry name" value="Asp/Glu/hydantoin_racemase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001920">
        <property type="entry name" value="Asp/Glu_race"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004380">
        <property type="entry name" value="Asp_race"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21198:SF7">
        <property type="entry name" value="PTHR21198:SF7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01177">
        <property type="entry name" value="Asp_Glu_race"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53681">
        <property type="entry name" value="SSF53681"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00035">
        <property type="entry name" value="asp_race"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="235" mass="25649" checksum="5B35EAF03AB3E339" modified="2016-01-20" version="1">MKTIGMIGGMSWESSIEYYRITNQRVREKLGGLHSAKSVMVSVDFAEIEVLQSSGRWDEATQMMVDAALQVQRGGADFLMICTNTMHRMAEEVRAALQIPLLHIADATAARVKQTGMTKIGLLGTRFTMEEDFYCGRLESLHGLQVLVPNAAGRGLVHRVIYDELVLGQTKPASRAEFARIISQMQAEGAQGVILGCTEIGLLVKQGDVDLPLFDTTRIHAEAAVDAALGELDLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNH1</accession>
    <name>A0A0N8GNH1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GntR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_07855</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000020">
        <property type="protein sequence ID" value="KPL78082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062438.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000020.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78082">
        <property type="protein sequence ID" value="KPL78082"/>
        <property type="gene ID" value="ADN00_07855"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2864"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="1">
        <location>
            <begin position="11"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="124" mass="13813" checksum="10EA45C79459A9B5" modified="2016-01-20" version="1">MDIVISNTSGDPIYQQIFDQISAQIIKGQLPSETCLPPIRTVAKELRISVITVKRAWEELEHAGLIYTMAGKGCFVSSLQPNVLNAKRDQLAGEKLAKDLEYYKTLGLSLDEIIAMLKKIYDEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNJ4</accession>
    <name>A0A0N8GNJ4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_07300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062323.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78266">
        <property type="protein sequence ID" value="KPL78266"/>
        <property type="gene ID" value="ADN00_07300"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="678" mass="75618" checksum="D8BE6AF6099C5B04" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNV7</accession>
    <name>A0A0N8GNV7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NifU domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_04800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79170.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061818.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04800"/>
    <dbReference type="EnsemblBacteria" id="KPL79170">
        <property type="protein sequence ID" value="KPL79170"/>
        <property type="gene ID" value="ADN00_04800"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001075">
        <property type="entry name" value="NIF_FeS_clus_asmbl_NifU_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01106">
        <property type="entry name" value="NifU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="SSF117916"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NifU" evidence="1">
        <location>
            <begin position="18"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79170.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="83" mass="9372" checksum="7C49D5E9B592190F" modified="2016-01-20" version="1">MSEKPTEKFTIEEQLKGLIETLDSYIAQYHGGSVELVEFKDNKVKVHMGGACEECPVSPEIGIRWVAGTIKQFFPEIESIERV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNX9</accession>
    <name>A0A0N8GNX9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_03195</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000014">
        <property type="protein sequence ID" value="KPL79346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061516.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000014.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79346">
        <property type="protein sequence ID" value="KPL79346"/>
        <property type="gene ID" value="ADN00_03195"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032688">
        <property type="entry name" value="ABC2_membrane_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011397">
        <property type="entry name" value="YhfC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12679">
        <property type="entry name" value="ABC2_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10086">
        <property type="entry name" value="YhfC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="71"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="111"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="165"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="198"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="231"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="286"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="340"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="379"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="416"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="449"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="491"/>
            <end position="516"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL79346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="521" mass="56614" checksum="4661894F05B6E951" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GP36</accession>
    <name>A0A0N8GP36_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_02240</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000009">
        <property type="protein sequence ID" value="KPL79802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061334.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000009.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02240"/>
    <dbReference type="EnsemblBacteria" id="KPL79802">
        <property type="protein sequence ID" value="KPL79802"/>
        <property type="gene ID" value="ADN00_02240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009002">
        <property type="term" value="F:serine-type D-Ala-D-Ala carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005311">
        <property type="entry name" value="PBP_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036138">
        <property type="entry name" value="PBP_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017790">
        <property type="entry name" value="Penicillin-binding_protein_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03717">
        <property type="entry name" value="PBP_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56519">
        <property type="entry name" value="SSF56519"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03423">
        <property type="entry name" value="pbp2_mrdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="domain" description="PBP_dimer" evidence="4">
        <location>
            <begin position="58"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="3">
        <location>
            <begin position="301"/>
            <end position="675"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF03717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL79802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="690" mass="76524" checksum="5CB95D1151DE4FE8" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GP51</accession>
    <name>A0A0N8GP51_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_02045</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000008">
        <property type="protein sequence ID" value="KPL79922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061300.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000008.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79922">
        <property type="protein sequence ID" value="KPL79922"/>
        <property type="gene ID" value="ADN00_02045"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2838"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="220"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="254"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="286"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="315"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="350"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="379"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="416" mass="43892" checksum="0F85ABD72126F24D" modified="2016-01-20" version="1">MTTIKTLLKNRDLLTLGFSESISNIGNWITMMAVFAMVVFRGDGGLLQSSAIYLAGLLPTLLASPLVGWLVDRVERRRLMVMSEAASGLVIAGLFFTDDFVWICVLLALQAVSIAVMSPARQAVLPQLVAREELTRANAFLQQLNGMVKIAAPMLAGGLLAALEPRQAILINVATFGCSALILSRLPLLPAAQEKTSRESAAQPAEGGGRVLKGIPGLRLLYGTMFFSVLVLIGFDVIGAVYVRDILQGGEALMGLLIGLVGAGTLAAGAFLMLSKRRQPRLWRDILLGLGLLACIPLAFSLAPLLGDARWMRLLAQAGCLAGGVGNGLLVIQSAVLLQTLTPARWLGRAGGLLQSVVVAGQIAGIVLTPLLVPAFLKMGSYFLLSALVLALVGVYSMLSLKMGQAGQPILSSERP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GPD4</accession>
    <name>A0A0N8GPD4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF1648 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_01720</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061233.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01720"/>
    <dbReference type="EnsemblBacteria" id="KPL80586">
        <property type="protein sequence ID" value="KPL80586"/>
        <property type="gene ID" value="ADN00_01720"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1106"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012867">
        <property type="entry name" value="DUF1648"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026272">
        <property type="entry name" value="SdpI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025962">
        <property type="entry name" value="SdpI/YhfL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37810:SF5">
        <property type="entry name" value="PTHR37810:SF5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07853">
        <property type="entry name" value="DUF1648"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13630">
        <property type="entry name" value="SdpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038959">
        <property type="entry name" value="SdpI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="187"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1648" evidence="2">
        <location>
            <begin position="12"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL80586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="217" mass="24153" checksum="77FF9C97D9DB51B9" modified="2016-01-20" version="1">MKTKTTLIISLLIIALVFVSGWLVYSQMPGPVITHWNAQGQPDGYSSKTTAMVLMPLMMLFTSALLFGVPLIDPLRKNVESFRGIYNQTILVVNGFLLVVHVVSLAWNMGWRININVVMLVAVGLMLFLLGRLMSHARRNYFFGIRTPWTLSSDLVWEKTHRFGGKVFQVACGALLLGALIPDAAFAVIMLVVLGSALVPVVYSYVVWRQIEQQVGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GPG6</accession>
    <name>A0A0N8GPG6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01245</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000003">
        <property type="protein sequence ID" value="KPL80842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061145.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01245"/>
    <dbReference type="EnsemblBacteria" id="KPL80842">
        <property type="protein sequence ID" value="KPL80842"/>
        <property type="gene ID" value="ADN00_01245"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="326"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="333"/>
            <end position="362"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="362" mass="41058" checksum="E3FA933BED9D60C7" modified="2016-01-20" version="1">MQDYDQEENNRQIPFSEVIEALLNNQQPFPAIMLPSFSDLSEENLAALQTIWLQIQPQRRAALLEDLDEIQDRDTLSDFSSLSQFALEDPLPKVRTQAIDMLWDWPQKQLARQFMRMLENDPDENVRAAAATALGNYIYLGELDEFPSDLSVQIVETLVRVIKGKDDKTVRMRALESVSYSSNEAIPALIQAAFQDSDREWLISALFAMGRSGDEAWNPNVLSCLDHSVPEVQAEAVRAAGELEIQEARQPLIDMLEEYETLDDNVRIAAVVSLSRIGGEGVRQSLEAMLEEINDDEEADIISAALENLDFVDLGLLPGMFDFSPIRPHEDDEDDSDYLEDWELDDENEEDWDLDNGAEEDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GPK3</accession>
    <name>A0A0N8GPK3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_00310</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81138.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00310"/>
    <dbReference type="EnsemblBacteria" id="KPL81138">
        <property type="protein sequence ID" value="KPL81138"/>
        <property type="gene ID" value="ADN00_00310"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3455"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00085">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002711">
        <property type="entry name" value="HNH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003615">
        <property type="entry name" value="HNH_nuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018973">
        <property type="entry name" value="MZB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09369">
        <property type="entry name" value="DUF1998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01844">
        <property type="entry name" value="HNH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00507">
        <property type="entry name" value="HNHc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="1">
        <location>
            <begin position="49"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="2">
        <location>
            <begin position="269"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL81138.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="821" mass="91046" checksum="40EECE5CBD5F30E2" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WMZ5</accession>
    <name>A0A0P6WMZ5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_16760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064201.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL71359">
        <property type="protein sequence ID" value="KPL71359"/>
        <property type="gene ID" value="ADN00_16760"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="248"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL71359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="271" mass="29483" checksum="3016118AA6D9F05E" modified="2016-01-20" version="1">MVLPTQLTFPNRAAAAAPLIDTPAAIRQPAGQSHPAPGTASLSSLAAFSYQNQLTELSLSAHKTDLVYRKDNSLLLKATSRFDVTLKAQNTQLDLVVTADRLGLTQADFDALGGKPIEIRFSFSEMNAQIEFHSETRVVKKTRTVQEILQDLTEALTDIFSRRGDKSIAVLMDEEAFGVLTGDPKIAGLLDEVFALIEVINHLKLEEGQRDLYAILLSGKGKPYIDHQESTTANIESHTESVSLTILPPAEPLPAGEAPLPEPQESKEESL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WN23</accession>
    <name>A0A0P6WN23_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ATP synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_17065</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71405.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064259.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17065"/>
    <dbReference type="EnsemblBacteria" id="KPL71405">
        <property type="protein sequence ID" value="KPL71405"/>
        <property type="gene ID" value="ADN00_17065"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.475"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030257">
        <property type="term" value="C:type III protein secretion system complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046961">
        <property type="term" value="F:proton-transporting ATPase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030254">
        <property type="term" value="P:protein secretion by the type III secretion system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004100">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000194">
        <property type="entry name" value="ATPase_F1/V1/A1_a/bsu_nucl-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005714">
        <property type="entry name" value="ATPase_T3SS_FliI/YscN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022425">
        <property type="entry name" value="FliI_clade2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040627">
        <property type="entry name" value="T3SS_ATPase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00006">
        <property type="entry name" value="ATP-synt_ab"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02874">
        <property type="entry name" value="ATP-synt_ab_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18269">
        <property type="entry name" value="T3SS_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03497">
        <property type="entry name" value="FliI_clade2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01026">
        <property type="entry name" value="fliI_yscN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="AAA" evidence="6">
        <location>
            <begin position="161"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="118"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL71405.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="439" mass="47483" checksum="C080C0FAB977BFB7" modified="2016-01-20" version="1">MINPTLPDLSRFQDAIARLDTARVSGRVVQVVGLTIQAVGLDCQIGEVCEIVTNRHNRILSEVVGFQDDRILLMALGDMQGIQNDSPVVPIQKEFLTPVGEMLLGRVLDGLGRPIDGGPAIDSAPRRSTHANPPSPLQRPPITDPLITGVRVIDGMLTCGKGQRMGIFAGSGVGKSTLLGSIARNSKSDISVIALVGERGRELREFIERDLGPEGLARSVVVVSTSDQPALIRMRAAMVAMSIAEYFRDHGKDVTFLMDSVTRFAMAQREIGLAIGEPPASKGYTPSVFAMLPRLLERAGTSESGSITGYFTVLVEGDDFNEPISDAVRGILDGHIILSRELAARNHYPAIDVLSSVSRVMSAITPREHREVAAMARRHLATYEKARDLVNIGAYVSGSDPEIDAALKVMPDLTRFLQQNSNDVSSFEDTLMMLSSIKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WPN7</accession>
    <name>A0A0P6WPN7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH marR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_16195</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72027">
        <property type="protein sequence ID" value="KPL72027"/>
        <property type="gene ID" value="ADN00_16195"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01047">
        <property type="entry name" value="MarR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="144" mass="16348" checksum="9A389960EFB482D4" modified="2016-01-20" version="1">MLMGNISRLHATRADQSLEAIGLFRGQAILLMLLSHQDGLTHSEIAEKLEISPAAATKVIKRMEALHYLQRRPDPADERISRVFLEEESWTVIRQIKNAFQQIDQILLTDLSPDEKDMLIKLLNKVYANLLEQPAGPPEIQPDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WRE5</accession>
    <name>A0A0P6WRE5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphohydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_17335</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71493.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17335"/>
    <dbReference type="EnsemblBacteria" id="KPL71493">
        <property type="protein sequence ID" value="KPL71493"/>
        <property type="gene ID" value="ADN00_17335"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.531"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037522">
        <property type="entry name" value="HD_GYP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51832">
        <property type="entry name" value="HD_GYP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAC" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="domain" description="HD-GYP" evidence="2">
        <location>
            <begin position="21"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL71493.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="204" mass="23494" checksum="BF96D6C645F64B55" modified="2016-01-20" version="1">MRDITERRQSEDYILKANFELNLAYKETLDGWGRALELRDDETEGHTRRVTEATVRLAMIMNASVEEIVHIRRGALLHDIGKIGIPDSILLKPGPLTEEEWAIMKMHPVFAYQLLSPISYLKPALDIPLYHHERWDGSGYPKGLSGKDIPLAARIFAIIDVWDALLSNRPYRKAWPREKVVQYITEQSGIQFDPDIVPVFLKNF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WSX7</accession>
    <name>A0A0P6WSX7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Purine nucleoside phosphorylase</fullName>
            <shortName evidence="1">PNP</shortName>
            <ecNumber evidence="1">2.4.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_18265</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Purine nucleoside phosphorylase involved in purine salvage.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a purine D-ribonucleoside + phosphate = a purine nucleobase + alpha-D-ribose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:19805"/>
            <dbReference type="ChEBI" id="CHEBI:26386"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57720"/>
            <dbReference type="ChEBI" id="CHEBI:142355"/>
            <dbReference type="EC" id="2.4.2.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; purine nucleoside salvage.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homohexamer. Dimer of a homotrimer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="1">Although this enzyme belongs to the family of MTA phosphorylases based on sequence homology, it lacks several conserved amino acids in the substrate binding pocket that confer specificity towards MTA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PNP/MTAP phosphorylase family. MTAP subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.1" evidence="1"/>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064486.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18265"/>
    <dbReference type="EnsemblBacteria" id="KPL70011">
        <property type="protein sequence ID" value="KPL70011"/>
        <property type="gene ID" value="ADN00_18265"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2959"/>
    <dbReference type="UniPathway" id="UPA00606"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017061">
        <property type="term" value="F:S-methyl-5-thioadenosine phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09010">
        <property type="entry name" value="MTAP_SsMTAPII_like_MTIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01963">
        <property type="entry name" value="MTAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010044">
        <property type="entry name" value="MTAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42679">
        <property type="entry name" value="PTHR42679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="SSF53167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="1" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PNP_UDP_1" evidence="2">
        <location>
            <begin position="38"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphate binding" evidence="1">
        <location>
            <begin position="48"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
        </ligand>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="1">
        <location>
            <position position="163"/>
        </location>
    </feature>
    <feature type="site" description="Important for substrate specificity" evidence="1">
        <location>
            <position position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL70011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="262" mass="28383" checksum="DDA1D796F1AF1E79" modified="2016-01-20" version="1">MLSAIIGGTGVYGIPGGVFTEEIMVTPFGKAKVYRGEGEYADLVFLARHGVNHSVPPHKINYKANIKALSMLGVKNVLATFAVGSLRESVPPLGLVALDQFLDFTSGRDFTFYEGGKWGFDHCVMTHPYCTSLRKRLLEVAKEKALPIQSAGTYVCTNGPRLETAAEVRMYAQLGGDVVGMTGVPEAPLARELGLHYAAVAFSINWCAGLKSEVMEMHEDGLEALKASILDLFITTLRSVQISGCECEHASLGYHPPVEEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WTX9</accession>
    <name>A0A0P6WTX9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Phosphate-specific transport system accessory protein PhoU</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_18295</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Plays a role in the regulation of phosphate uptake.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PhoU family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064660.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18295"/>
    <dbReference type="EnsemblBacteria" id="KPL70166">
        <property type="protein sequence ID" value="KPL70166"/>
        <property type="gene ID" value="ADN00_18295"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2965"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030643">
        <property type="term" value="P:cellular phosphate ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045936">
        <property type="term" value="P:negative regulation of phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.220">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028366">
        <property type="entry name" value="P_transport_PhoU"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038078">
        <property type="entry name" value="PhoU-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026022">
        <property type="entry name" value="PhoU_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42930">
        <property type="entry name" value="PTHR42930"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01895">
        <property type="entry name" value="PhoU"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003107">
        <property type="entry name" value="PhoU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02135">
        <property type="entry name" value="phoU_full"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PhoU" evidence="2">
        <location>
            <begin position="19"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="PhoU" evidence="2">
        <location>
            <begin position="120"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR003107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL70166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="224" mass="25624" checksum="DF57DE8A08396BA7" modified="2016-01-20" version="1">MPRETLDRRIHHIQEEILLLGSMVEQAMLNSIDALKRRDVEASKQIYEDDYLVNEKRFAIENAILIIIATQQPIAHDLRLLAAMLEVITELERMGDYAKGIAKVNIKLADSDLSIPMREINRMCELSVSMLHRALSAFVSENPKEASKIPEEDKAVDELYNVIYRILVNNMIANPACIDHANLLMWVAHNLERMADRVTNICERTVFIATGEVLEMDTSDDENY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WVX2</accession>
    <name>A0A0P6WVX2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_18810</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064580.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70096">
        <property type="protein sequence ID" value="KPL70096"/>
        <property type="gene ID" value="ADN00_18810"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="75" mass="8566" checksum="479B8D464948B62E" modified="2016-01-20" version="1">MTTTKVYPFETVEEQRARIEYEDALISAYVPESDTMTREEALALANERDLQAAMALRDDVITLENLQIAISRSRT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WX96</accession>
    <name>A0A0P6WX96_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="14">Pyruvate-flavodoxin oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">ADN00_17745</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="12">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="12">Binds 3 [4Fe-4S] clusters per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the pyruvate:ferredoxin/flavodoxin oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000043">
        <property type="protein sequence ID" value="KPL70888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064389.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000043.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17745"/>
    <dbReference type="EnsemblBacteria" id="KPL70888">
        <property type="protein sequence ID" value="KPL70888"/>
        <property type="gene ID" value="ADN00_17745"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2141"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016903">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022900">
        <property type="term" value="P:electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07034">
        <property type="entry name" value="TPP_PYR_PFOR_IOR-alpha_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.920.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033412">
        <property type="entry name" value="PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037112">
        <property type="entry name" value="Pyrv-flavodox_OxR_EKR_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019456">
        <property type="entry name" value="Pyrv-flavodox_OxRtase_EKR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019752">
        <property type="entry name" value="Pyrv/ketoisovalerate_OxRed_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002880">
        <property type="entry name" value="Pyrv_Fd/Flavodoxin_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011895">
        <property type="entry name" value="Pyrv_flavodox_OxRed"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002869">
        <property type="entry name" value="Pyrv_flavodox_OxRed_cen"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10371">
        <property type="entry name" value="EKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17147">
        <property type="entry name" value="PFOR_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01558">
        <property type="entry name" value="POR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01855">
        <property type="entry name" value="POR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000159">
        <property type="entry name" value="NifJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00890">
        <property type="entry name" value="EKR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53323">
        <property type="entry name" value="SSF53323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02176">
        <property type="entry name" value="pyruv_ox_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 12" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5 9" id="KW-0249">Electron transport</keyword>
    <keyword evidence="7 12" id="KW-0408">Iron</keyword>
    <keyword evidence="8 12" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="14" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 9" id="KW-0813">Transport</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="13">
        <location>
            <begin position="689"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="13">
        <location>
            <begin position="745"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="region of interest" description="Thiamine pyrophosphate binding" evidence="10">
        <location>
            <begin position="980"/>
            <end position="983"/>
        </location>
    </feature>
    <feature type="region of interest" description="Thiamine pyrophosphate binding" evidence="10">
        <location>
            <begin position="1009"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="114"/>
        </location>
        <ligand>
            <name>pyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="698"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="701"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="704"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="708"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="754"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="757"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="760"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="764"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="828"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="831"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="833"/>
        </location>
        <ligand>
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10 12">
        <location>
            <position position="856"/>
        </location>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="1089"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>3</label>
        </ligand>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="11">
        <location>
            <position position="31"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="11">
        <location>
            <position position="64"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="11">
        <location>
            <position position="114"/>
        </location>
    </feature>
    <feature type="site" description="Important for catalytic activity" evidence="11">
        <location>
            <position position="1014"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR000159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000159-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000159-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000159-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KPL70888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="1192" mass="130856" checksum="1F9AF5C0895D22D4" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZ50</accession>
    <name>A0A0P6WZ50_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">LacI family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_15890</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL71985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064175.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL71985">
        <property type="protein sequence ID" value="KPL71985"/>
        <property type="gene ID" value="ADN00_15890"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3611"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00036">
        <property type="entry name" value="HTHLACI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="2"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL71985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="334" mass="36593" checksum="6F788A28A1F9CB47" modified="2016-01-20" version="1">MPTIREVAQKAGVSYTTVSHVINNTRRVSTPVRERVLAAMQELGYRPNALARSLRSGETKTIGLILPDSANPFFAEVGRAIENAAFRSQYSVILCNTEGDQAKERVYTEVLQNKQVDGLIFVAAGDQPDALQEIATRGLPVVVIDRDCSQLELDTVITDNLSGGRQAGSHLAQIPNLRAACITGPSNLTPSAQRLVGFQQALHEAGIELREEWVLRGDFHPHSGYQAALHWLKAAQRPNAIFCCNDMMAIGVLRAAAELGVMVPQELEVIGFDDIELASYTHPPLTTVAQPKAQIGETAVRLLLERIADGWLPARREILPTTLIIRKTTHEEKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZI1</accession>
    <name>A0A0P6WZI1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Formate transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_15430</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FNT transporter (TC 2.A.44) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063928.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15430"/>
    <dbReference type="EnsemblBacteria" id="KPL72214">
        <property type="protein sequence ID" value="KPL72214"/>
        <property type="gene ID" value="ADN00_15430"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.788"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015499">
        <property type="term" value="F:formate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000292">
        <property type="entry name" value="For/NO2_transpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024002">
        <property type="entry name" value="For/NO2_transpt_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023999">
        <property type="entry name" value="Formate_transptr_FocA_put"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30520">
        <property type="entry name" value="PTHR30520"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01226">
        <property type="entry name" value="Form_Nir_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00790">
        <property type="entry name" value="fnt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04060">
        <property type="entry name" value="formate_focA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01005">
        <property type="entry name" value="FORMATE_NITRITE_TP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="36"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="70"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="112"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="162"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="196"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="252"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL72214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="284" mass="30411" checksum="E37FF0C5E20D1873" modified="2016-01-20" version="1">MAENNIRIDSLVPAEMAQKAEDVGVKKASLDFWTMFALAILAGAFISLGAVFATTVGTGGGDLPFGVNKLLMGLVFTVGLIMVIVGGAELFTGNNLIVMAFMSGKVSLGKLLRNWAIVYFGNLVGSVLTAYFMFLTKQYTFAKGALGLTILNIGESKTALEFVPALALGVMCNALVCMAVWLTFSARTTTDKILAIIPPISAFVAAGMEHSVANMYFIPIALFVKYFGDPSFFEAIGKTAADFPHLTVNNFFIANLLPVTIGNIIGGVVLVGVVYWFIYLRKKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X0I5</accession>
    <name>A0A0P6X0I5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13670</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063584.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000032.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13670"/>
    <dbReference type="EnsemblBacteria" id="KPL74345">
        <property type="protein sequence ID" value="KPL74345"/>
        <property type="gene ID" value="ADN00_13670"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="206"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="262"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="362"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="508" mass="56834" checksum="F7355DF269C3A4FB" modified="2016-01-20" version="1">MSVKSSPQNNEQQVEGLMLVICLLLVWIISARAPLDTDMWWHLRAGESTLASGKPLLMDIFSFTRGGEGWMNHSWFSEVLMALAYRGLGYSGLAGWVALTACATMLMVWTRLEGPPLYRAVWLLAAAIFSSLAWAPRPQIMSLLFLAVLEELIETSRQGKPKWLWALPLLFAVWSNLHAGYSLGFILIAAILTGDGLDWLLTGKSLKPASALALWAGLAGLATLINPNGLNTWRVVFSTVDVQALQQFISEWASPDFHQLDQLLFLLFFLFCTVILVLCKERVSGADLAKFFAFSLLAFYARRNIAPFAVIAAPAAARALHRGLDGLIAPGSPLKRVSLAMRQWFQQANRPQHPFLLRARKWLNLGMAAVLGVVGLGKLYSVSHPVMMDRYLSESYPVKAVEWLRSQSDMGNLLNEYDWGGYLIWFARDVPVFIDGRTDLYGDKILGDWIRLVQGGEGADELLERYEIETLLLRPNRPLARLLVAEDWKTVYADDQAVILQREAKNQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X2E9</accession>
    <name>A0A0P6X2E9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13150</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000030">
        <property type="protein sequence ID" value="KPL75177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063481.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000030.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL75177">
        <property type="protein sequence ID" value="KPL75177"/>
        <property type="gene ID" value="ADN00_13150"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2881"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL75177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="246" mass="26119" checksum="0AD2006C5C3288BF" modified="2016-01-20" version="1">MIDYGNDEVKPNRGGWFLNFLTIVLLLGIIAAIALTVLIFQNPQAVYNPFPPPTLPAAIVLPSATPTVIALPPTWTPVVTETPAPTATVATPTRVPDVATPIPNDSDLLFTATPTEKASSIYPFATQSAPAAIDATVLFPERVCNWMGVGGQVVDMEARPLTGVGVQLGGSIGGKTVSLTSLTGTALQYGTAGYEFTISDVPTATQGSFWIRLVDQANLPLSGRIYFDTYAECEKNLTIINLKQVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X2K2</accession>
    <name>A0A0P6X2K2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_09675</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062798.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76863">
        <property type="protein sequence ID" value="KPL76863"/>
        <property type="gene ID" value="ADN00_09675"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="170" mass="19540" checksum="52E1CC9E6C84335B" modified="2016-01-20" version="1">MPSLPEAMQEFKAQLQRGVVQQAYRGLMDYLMTLKTYLKTRYPDYFVSGGLYQGYMDMAYFSFHPEAFKRRGLKIAVVFNFDTFAFEVWLGGYNKQVQAQYWALFQQSGWNQYPLVPSLKGEDAIVTHTLVETPDFNDLDALTQRIEAGTLTFIGEIEAFLSAQNDLPRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X2K5</accession>
    <name>A0A0P6X2K5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_09730</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062809.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09730"/>
    <dbReference type="EnsemblBacteria" id="KPL76872">
        <property type="protein sequence ID" value="KPL76872"/>
        <property type="gene ID" value="ADN00_09730"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00037">
        <property type="entry name" value="Fer4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12641">
        <property type="entry name" value="Flavodoxin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="4">
        <location>
            <begin position="3"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="193"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="227"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL76872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="274" mass="30552" checksum="7A9E929FC1016203" modified="2016-01-20" version="1">MKVYLIYFSQTNNTRSVAEAIAESLEQQGAVTQMVPLKKANELEVIDADLLGIGTACFSSQAPTPVKRFLKTLPRLDQKKASVFATSGSAPGRVLYDLAHLLRRKGADVIGGFLTYGEVHHPAPCLLGRMANRPDTQDLAQARRFAEAVFEHIAKGRPGVVAASRPETDHPKWGFYDFVALISSDSVLRLLLPKPRLNENQCKQCQWCVSECPMNAIVMDAYPRIGDQCIRCYHCFNGCPQKAFQVNWVPSNLVVSLFYNKTFARWFGELKPDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X2X6</accession>
    <name>A0A0P6X2X6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Methionine gamma-lyase</fullName>
            <ecNumber evidence="4">4.4.1.11</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_14390</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the trans-sulfuration enzymes family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.4.1.11" evidence="4"/>
    <dbReference type="EMBL" id="LGCL01000034">
        <property type="protein sequence ID" value="KPL73753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063724.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000034.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14390"/>
    <dbReference type="EnsemblBacteria" id="KPL73753">
        <property type="protein sequence ID" value="KPL73753"/>
        <property type="gene ID" value="ADN00_14390"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1397"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018826">
        <property type="term" value="F:methionine gamma-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019346">
        <property type="term" value="P:transsulfuration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00614">
        <property type="entry name" value="CGS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000277">
        <property type="entry name" value="Cys/Met-Metab_PyrdxlP-dep_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11808">
        <property type="entry name" value="PTHR11808"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01053">
        <property type="entry name" value="Cys_Met_Meta_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001434">
        <property type="entry name" value="CGS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00868">
        <property type="entry name" value="CYS_MET_METAB_PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="209"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR001434-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL73753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="395" mass="43462" checksum="9C834389750F9F47" modified="2016-01-20" version="1">METKDKKFATRVVHAGQHPDHETGALVSPMYLTSTFVFTPEKMERYMAGDKEGIYTYGRSRNPTQNMFQEKIASLEGGEMALATASGMAAISTALLGTVHAGDHIIACKTVYGGTHALFTSIFPELNIEVTFLPEMTPAALDAAKRPNTKAVYVETVLNPTLEVLDLQPVFDWARANKVRSFVDNTFTTPYLYRPIEHGADVVLHSTTKYINGHGDHIGGAIVCDAVYHEKLRSSVYQEFGPVPSPFACWLGLRGLKTLHLRMRAHCENAMKLAEWLEQHPKVVSVSYPGLKSHPQHDVAARQFENGFGGMVGFCVEGGIREAQKVINAMQMAYYAVSLGDLDTLVEQPATMTHGKMGPEARKAMGIEDSYIRLSVGVEDVDDIIADIDNALKQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X302</accession>
    <name>A0A0P6X302_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_13965</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063644.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000033.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74107">
        <property type="protein sequence ID" value="KPL74107"/>
        <property type="gene ID" value="ADN00_13965"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1891"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL74107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="423" mass="44674" checksum="549083A8E866C24E" modified="2016-01-20" version="1">MSYPLSSEVSPGQPTAAAHYNNLRADALRLGCADADAVTLAALLARWEDGLRLDVLGSNRVRVPASPAEPVSLVIDGAPLQITQPADLSVSSAPSGAACDYFVFALRSPGSSGFCLDVNTSSLESSGRRRIGRFYWDGTRITPGSLRSERGQFLQGVLGSLAAQSAGGRLSLSAGEGLPPQDIAAAGTVYYGPWRGNRVGLYSEGFGWREWEFAELSLSLQGLAANTNADIFLRHDGSALVLEKTAWSSSTQRAAALRRQDGVLVKDGAPGWRYLGTLRTTAEAGKCDDSGLKRFVWNAENRAPRGLRWSSETLHTYDAGVYRAWNNDASQCAQAVVGLAGEAAWLYATVDATPASMAVYGVGLNSTNLPAFETGMLTGSARQRAACGGYASPQAGLNTVCVLEYSSGVSTFTRAQINGLLMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X411</accession>
    <name>A0A0P6X411_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 8">Adenylate kinase</fullName>
            <shortName evidence="6">AK</shortName>
            <ecNumber evidence="6 8">2.7.4.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">ATP-AMP transphosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">ATP:AMP phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Adenylate monophosphate kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">adk</name>
        <name evidence="10" type="ORF">ADN00_12500</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP. Plays an important role in cellular energy homeostasis and in adenine nucleotide metabolism.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 8">
            <text>AMP + ATP = 2 ADP</text>
            <dbReference type="Rhea" id="RHEA:12973"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Purine metabolism; AMP biosynthesis via salvage pathway; AMP from ADP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6 8">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="6">Consists of three domains, a large central CORE domain and two small peripheral domains, NMPbind and LID, which undergo movements during catalysis. The LID domain closes over the site of phosphoryl transfer upon ATP binding. Assembling and dissambling the active center during each catalytic cycle provides an effective means to prevent ATP hydrolysis. Some bacteria have evolved a zinc-coordinating structure that stabilizes the LID domain.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the adenylate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.3" evidence="6 8"/>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063349.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12500"/>
    <dbReference type="EnsemblBacteria" id="KPL76147">
        <property type="protein sequence ID" value="KPL76147"/>
        <property type="gene ID" value="ADN00_12500"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3981"/>
    <dbReference type="UniPathway" id="UPA00588">
        <property type="reaction ID" value="UER00649"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004017">
        <property type="term" value="F:adenylate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044209">
        <property type="term" value="P:AMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01428">
        <property type="entry name" value="ADK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00235">
        <property type="entry name" value="Adenylate_kinase_Adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006259">
        <property type="entry name" value="Adenyl_kin_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000850">
        <property type="entry name" value="Adenylat/UMP-CMP_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033690">
        <property type="entry name" value="Adenylat_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007862">
        <property type="entry name" value="Adenylate_kinase_lid-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23359">
        <property type="entry name" value="PTHR23359"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05191">
        <property type="entry name" value="ADK_lid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00094">
        <property type="entry name" value="ADENYLTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01351">
        <property type="entry name" value="adk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00113">
        <property type="entry name" value="ADENYLATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0545">Nucleotide biosynthesis</keyword>
    <keyword evidence="4 6 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="ADK_lid" evidence="9">
        <location>
            <begin position="127"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="NMP" evidence="6">
        <location>
            <begin position="30"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="LID" evidence="6">
        <location>
            <begin position="126"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="10"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="57"/>
            <end position="59"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="85"/>
            <end position="88"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="127"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="130"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>structural</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="133"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>structural</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="136"/>
            <end position="137"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
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    <feature type="binding site" evidence="6">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>structural</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>structural</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="160"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
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        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="199"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007220"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF05191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL76147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="216" mass="23766" checksum="DBEB2FE957C9D43D" modified="2016-01-20" version="1">MYVVLLGPPGAGKGTQAQAISQELKLAHISSGDIFRENLKKETELGKLAKGYMDRGELVPDDVTISMIEERLSRPDCAEGALLDGFPRTPAQAEALSVMLAKQGKQIDVVPLITVPAEVLVERLSGRWTCPTCGYVYHSVFNPPKQTGVCDTDGAALYQREDDKPETVKNRIRVYESQTAPLIEYYQKRNLLAEVDGTLPIEHVTQSLLEVIKKVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X447</accession>
    <name>A0A0P6X447_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_08020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062469.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08020"/>
    <dbReference type="EnsemblBacteria" id="KPL77823">
        <property type="protein sequence ID" value="KPL77823"/>
        <property type="gene ID" value="ADN00_08020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.604"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000801">
        <property type="entry name" value="Esterase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00756">
        <property type="entry name" value="Esterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL77823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="260" mass="30386" checksum="9C396491E0A2AA6C" modified="2016-01-20" version="1">MNISYHRWFSENLNQDMEIKVYGSKGVALLAFPTLGGRFYDFENFGMIAAVEDQIEAGNLTCFTVDSFDHQSWLNTSLEPAERARLHEQYATYIFEEVVPFIHRQSTDQVKILLTGCDMGGYHAANFFFRRPDLFAGFICLSGFFDLQRFTDNFVDETIYYNSPLHYLPRLTDIWYLDLYRQSHLVVCTGQGMWERQMVANAHALKRVLQEKDISCRVDFWGFEADHDWSWWRKQLPYYLKPILAAIASSENTGEMNNPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X561</accession>
    <name>A0A0P6X561_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Metallophos domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10325</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062922.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76969">
        <property type="protein sequence ID" value="KPL76969"/>
        <property type="gene ID" value="ADN00_10325"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2531"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP_ApaH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos" evidence="1">
        <location>
            <begin position="49"/>
            <end position="249"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="324" mass="36140" checksum="0B6D3A80CF605261" modified="2016-01-20" version="1">MKTRFFPLLWILLAAIILTAAYTYFDNQRVILVRQQVEIENLPPEFEGFTILQVSDLHGKRFGANQQRLLELINNTPYDMLAISGDMDSGYQPDSQPFFELLDGLENKENIFYTSGNSGPYAFEELTGALTESGQVLQSKGVKPLNQLYTLQRGESRLYVGEFWLLDVIKIYNLGFSQQQLDQPGLSAADREYYQAAQQYGQELLAQLQPIQPGDTLIGITHVPFSIDSVSEMPAIAPSYDLVLAGHYHGGQIRLPLIGAVYIPDGASERGGFFPARDEVSGLKDWGDFQQYVSRGLGASSGIPLLNFRLFNTPEINLITLTAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X575</accession>
    <name>A0A0P6X575_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Branched-chain amino acid ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_10390</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AzlC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062932.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10390"/>
    <dbReference type="EnsemblBacteria" id="KPL76979">
        <property type="protein sequence ID" value="KPL76979"/>
        <property type="gene ID" value="ADN00_10390"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2544"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011606">
        <property type="entry name" value="Brnchd-chn_aa_trnsp_permease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34979">
        <property type="entry name" value="PTHR34979"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03591">
        <property type="entry name" value="AzlC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="195"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="219"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL76979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="241" mass="25580" checksum="04EB3D551D539948" modified="2016-01-20" version="1">MSTPELTEEKIHSPAARWMSGMASALPIVIGYVTIGFAYGVLANKAGLSMLNTLLMSLIVFAGSAQFIAVGLFAAGAPLLSIIATTFVVNLRHLLMSASIAPKLQGWGKARLAWYAFELTDETFGLHSAHFAQHTPDPLWVFAANLTSQVAWVAGSWLGAAFGQLISDVRPYALDYALPAMFIALLVMQLRGLNTLLVAAAAGVVSTGLMLAGMDQWSVILATLLGATLGMGLELWINKES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5B8</accession>
    <name>A0A0P6X5B8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF2202 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13195</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000030">
        <property type="protein sequence ID" value="KPL75185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13195"/>
    <dbReference type="EnsemblBacteria" id="KPL75185">
        <property type="protein sequence ID" value="KPL75185"/>
        <property type="gene ID" value="ADN00_13195"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019243">
        <property type="entry name" value="DUF2202"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012347">
        <property type="entry name" value="Ferritin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009078">
        <property type="entry name" value="Ferritin-like_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09968">
        <property type="entry name" value="DUF2202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47240">
        <property type="entry name" value="SSF47240"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF2202" evidence="1">
        <location>
            <begin position="14"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL75185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="109" mass="12053" checksum="F62B031300769F1D" modified="2016-01-20" version="1">MQTYLSISAQLGDESVFDEIAASEQRHLDTLIRQAEKYGVELPAMNEISPVEFGSLEEACAIGAAAEIADAELYDVLMAQTERSDLLRVYTNLQRASLEQHLPAFESCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5J1</accession>
    <name>A0A0P6X5J1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N_BRCA1_IG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_07695</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062397.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78326">
        <property type="protein sequence ID" value="KPL78326"/>
        <property type="gene ID" value="ADN00_07695"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032350">
        <property type="entry name" value="N_BRCA1_central"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16158">
        <property type="entry name" value="N_BRCA1_IG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132852" description="N_BRCA1_IG domain-containing protein" evidence="1">
        <location>
            <begin position="27"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="N_BRCA1_IG" evidence="2">
        <location>
            <begin position="135"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="230" mass="24595" checksum="765EA9CC2D95ACD0" modified="2016-01-20" version="1">MNIQRTRAAIVLAFITILLLAGCGPAAPQAAPTLNPTEMEQQVILLRTAAAETVAVQLTEQAALFPSATVTATATEAPTHTAQPAQAESTPITLPDATQAPTTSVVLVPTATARPAANTTPAECKVVSVSPVYNNQFRPSTDFDVRITVQNTGTFTWSDDDMELRYITGDKYETASDSYKLTKEAKPGENVEFAIDMITPKDAGQYSAAWGLFRGSKNLCVIYINLQVVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X666</accession>
    <name>A0A0P6X666_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Thiamine ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_13525</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063552.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000031.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13525"/>
    <dbReference type="EnsemblBacteria" id="KPL74851">
        <property type="protein sequence ID" value="KPL74851"/>
        <property type="gene ID" value="ADN00_13525"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="82"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="113"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="253"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="78"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL74851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="289" mass="32298" checksum="444A332FEBBFBDD8" modified="2016-01-20" version="1">MRKPIPTPRWMQKNVPRMIQYIILTVTSTMVFIPIVILLFGSVKTTGQMYSNPYSIPNPPNWDNIINILSTSSFWRLMKNSLIVMLSTTAITVLVCSLVAFIFARMEFRGKNFFFNLFTLGLMFPINVAILPVYFVLRQMTQFGINMIDSLAGVILVQTAFQLSGNIMILRGFFTAVPQDLQDAAYIDGCTNFDFFWRVMIPLVKPSLAAVAALVMIASWNDLLVPLVVLNSDSLWTLPLGVMQFQGQYGQDLALISAFVALSSIPTIIFYFFAEKQIVSGLTAGAVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7A2</accession>
    <name>A0A0P6X7A2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Glycosyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_07945</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062455.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77811">
        <property type="protein sequence ID" value="KPL77811"/>
        <property type="gene ID" value="ADN00_07945"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.590"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="27"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="214"/>
            <end position="393"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="425" mass="47266" checksum="3241DF586F0097A6" modified="2016-01-20" version="1">MSQSPLRIAMISYHTCPLATLGGKNTGGMNVYVRELTHYLGRAGVHVDVFTRSENEHVPHVLHDLGYGNRVVHIPAGPEHPLPKEELASHIPQFAEGILTFTREKNLQYDLVHSHYWMSGIASIDLQKEWRVPIISMFHTLQKLKNQIARSAEEREGQYRIDGEERVIQHSACIVTATPAEEKQLTALYHADPQKLCSIPPGVDTSHFYPIPADEAKAVVGIPEKDRMLLFVGRIEPLKGVDTLVRAIAHMRKLGVLGKCPHYLAIIGGEPDVSPENMDAEMKRLQELCQTLGIGDLVLFLGKRDQNLLPYYYSASEVVIMPSHYESFGMVALEAMACGKPVVASQVGGLAYLVQNNVTGILIPDGDPIALGETLTRLIRNDHLREQLGNQANQYAQAYSWEIIAEKMKKLYDEICLGQPVSGIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7H3</accession>
    <name>A0A0P6X7H3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Cell division protein FtsZ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ftsZ</name>
        <name evidence="7" type="ORF">ADN00_08055</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="4">Assembles at midcell at the inner surface of the cytoplasmic membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the FtsZ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08055"/>
    <dbReference type="EnsemblBacteria" id="KPL77911">
        <property type="protein sequence ID" value="KPL77911"/>
        <property type="gene ID" value="ADN00_08055"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.611"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051258">
        <property type="term" value="P:protein polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02201">
        <property type="entry name" value="FtsZ_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00909">
        <property type="entry name" value="FtsZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000158">
        <property type="entry name" value="Cell_div_FtsZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020805">
        <property type="entry name" value="Cell_div_FtsZ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045061">
        <property type="entry name" value="FtsZ/CetZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024757">
        <property type="entry name" value="FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30314">
        <property type="entry name" value="PTHR30314"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12327">
        <property type="entry name" value="FtsZ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00423">
        <property type="entry name" value="CELLDVISFTSZ"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="SSF52490"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="SSF55307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00065">
        <property type="entry name" value="ftsZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01134">
        <property type="entry name" value="FTSZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0717">Septation</keyword>
    <feature type="domain" description="Tubulin" evidence="5">
        <location>
            <begin position="17"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin_C" evidence="6">
        <location>
            <begin position="211"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="25"/>
            <end position="29"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="112"/>
            <end position="114"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="147"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL77911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="378" mass="39512" checksum="845B9FB7D24FB200" modified="2016-01-20" version="1">MSTNPVERTPLVARQPVLKVIGLGGGGSNAINRMIELGLTGVDFIAANTDAQALSRSLAPRKIQLGPSLTRGLGAGGNPEIGAAAAEESVRELKEAMTGADMVFLTAGMGGGTGTGSISVAARVARSLGAVTIAVVTTPFGFEVGRRQTNARNGLNMLRPHTDTLITVPNDRLLQVAPRDLTLELAFRLADDILRQGIQGITELITQTGVINVDFSHIQNLMRNGGGAILSIGYGQGENKALKAVHQALHHPILDSIPVENASGIIANFSGANDLSFIEVSEALCHLQEMAGAAIEIIPGVMSDENLHDRCQVILVITGLGATAVENVPAQVTQRAAASPAASVFPSSRPAKTPVPEMQLAAAQSDLDIPAFMRRRMH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7X1</accession>
    <name>A0A0P6X7X1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">AFOR_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_04480</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AOR/FOR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061757.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04480"/>
    <dbReference type="EnsemblBacteria" id="KPL79121">
        <property type="protein sequence ID" value="KPL79121"/>
        <property type="gene ID" value="ADN00_04480"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009055">
        <property type="term" value="F:electron transfer activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016625">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, iron-sulfur protein as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.569.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.599.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.9.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013984">
        <property type="entry name" value="Ald_Fedxn_OxRdtase_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013985">
        <property type="entry name" value="Ald_Fedxn_OxRdtase_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013983">
        <property type="entry name" value="Ald_Fedxn_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036503">
        <property type="entry name" value="Ald_Fedxn_OxRdtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001203">
        <property type="entry name" value="OxRdtase_Ald_Fedxn_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036021">
        <property type="entry name" value="Tungsten_al_ferr_oxy-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01314">
        <property type="entry name" value="AFOR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02730">
        <property type="entry name" value="AFOR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00790">
        <property type="entry name" value="AFOR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48310">
        <property type="entry name" value="SSF48310"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56228">
        <property type="entry name" value="SSF56228"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0408">Iron</keyword>
    <keyword evidence="7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AFOR_N" evidence="8">
        <location>
            <begin position="4"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL79121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="628" mass="69250" checksum="039F0215CB32D121" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X8B4</accession>
    <name>A0A0P6X8B4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">MarR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_07680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062394.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78323">
        <property type="protein sequence ID" value="KPL78323"/>
        <property type="gene ID" value="ADN00_07680"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3366"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000835">
        <property type="entry name" value="HTH_MarR-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01047">
        <property type="entry name" value="MarR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00598">
        <property type="entry name" value="HTHMARR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00347">
        <property type="entry name" value="HTH_MARR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50995">
        <property type="entry name" value="HTH_MARR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH marR-type" evidence="1">
        <location>
            <begin position="11"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="155" mass="17183" checksum="312937039C30D656" modified="2016-01-20" version="1">MATHYQGTEEEIRSLNAFIKLTRAANSVMSYLAANGAYSDLTITQFGVLETLYHLGPLPHCEISAKQLKSTGNMTLVIDNLEKRGLVKRVRSQDDRRVVTVHLTSEGKALISAIFPQHVERIVELMGALNAEEQEELGRLCKKLGISLAERVHPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X913</accession>
    <name>A0A0P6X913_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_17980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000044">
        <property type="protein sequence ID" value="KPL70766.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70766">
        <property type="protein sequence ID" value="KPL70766"/>
        <property type="gene ID" value="ADN00_17980"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70766.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="157" mass="17910" checksum="4CB48996CCD9DABC" modified="2016-01-20" version="1">MNTLRRLFGQKQSAPKKTSGPLDTHQAEKLWQEAYDFFRSDNKKDHIKAVEIALRLIEDGPNDAFTKSKLQCFIADIYSQKLEEHDKAIKYYQDALESDPGNSLAGSNLGFVYLNYKKDYESAAKVLQQTLDRGVSSAFVRESTKDWLAEAKQKLGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X956</accession>
    <name>A0A0P6X956_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DnaB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_02645</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000012">
        <property type="protein sequence ID" value="KPL79432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061411.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000012.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02645"/>
    <dbReference type="EnsemblBacteria" id="KPL79432">
        <property type="protein sequence ID" value="KPL79432"/>
        <property type="gene ID" value="ADN00_02645"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.860.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036185">
        <property type="entry name" value="DNA_heli_DnaB-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007693">
        <property type="entry name" value="DNA_helicase_DnaB-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016136">
        <property type="entry name" value="DNA_helicase_N/primase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00772">
        <property type="entry name" value="DnaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48024">
        <property type="entry name" value="SSF48024"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0235">DNA replication</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DnaB" evidence="3">
        <location>
            <begin position="6"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL79432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="486" mass="54038" checksum="9E6B1726A677D07D" modified="2016-01-20" version="1">MPDPIPPRDIDAEQALLGSIMIAPYLFEDLVTIVKAEYFYRNSHRWIWEAMNHLLESEQQIDHVTLCNALNTSGKLKEIGGPAYIMGLLNATPTSMHAESYAKIVREKAFKRKALEVATNLAQNAIQDKPLSEALQQMEKFFVSSSALSGVTERMVMTAEKLCLSEMGELTWILKDWIMAGGINLIAGMPAAGKSFLALDLAIGMASSGVAWDNQPVTQGKVLYHFLDGSYRGMRSRVLKLCHARGIQPPANLIFDFSPLNLKVPSEVLALRQRIHRLDASVVIFDVMAKFMPGADENSVAEISPMMNTLREIANQTGTTFILIHHLNKGGNTDLSYRVRGSSDILGSVDTAIVITHENQHSAHSMRTIIPQKVRESLPPAQLQFQIESTEDSIALRFSEANASELLRAPGQAELIFADILEYLQSVPAQEFKKNELISALQINSSARTIERAFSKLNNDPRIRVTKRGSFNTYQWEEDTPATPFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9F8</accession>
    <name>A0A0P6X9F8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061986.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78716">
        <property type="protein sequence ID" value="KPL78716"/>
        <property type="gene ID" value="ADN00_05590"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="164"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="307" mass="34422" checksum="9BC910585C01432A" modified="2016-01-20" version="1">MLQIRPCTEADIPALLNLIDAANQVDQAGWYYTTADLAEALQKDQPIPPDQRIHLLYHGDQLAGYYRLDAEDTLEGVKVLCFGCVHPAFRRQGLGARLLEQAAHTAQAAAPRGAKILFQVPARRNVPGIYALCEKSGLQMARQFSVLKRDTRQPIPPCQTKLSAQLNAFDPAHDGADLLAAFDQCFPGHSYKPEILDKEWRKTRENLGYWWVARDPTGLLTGFCLAGVEKEAEEEPIGLIDYLGVLPAARRQGLGRCLLYTAMHYLQMIGLPAIKLATEVDNLRALSLYYEAGFETWREARLYQKRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XA23</accession>
    <name>A0A0P6XA23_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_17130</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71415.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064271.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL71415">
        <property type="protein sequence ID" value="KPL71415"/>
        <property type="gene ID" value="ADN00_17130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007809">
        <property type="entry name" value="FlgN-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036679">
        <property type="entry name" value="FlgN-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05130">
        <property type="entry name" value="FlgN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140566">
        <property type="entry name" value="SSF140566"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL71415.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="172" mass="19652" checksum="C1B5ECA1DF00D879" modified="2016-01-20" version="1">MDHQQQTIKVNSLEALLVKQFRTLETLINISKIERELILDHRTDELMNVVEQKESVLDQLGLMEEDRRMLTEELAAALGLKLQRAGLDEILTVLETVAAERFYRLNEGILALVEQARELNMGNQVMARTAIEWLEATQMFLLNVSAPEVAYSYPGAARRVDSWATRAIDQRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XA86</accession>
    <name>A0A0P6XA86_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ald_Xan_dh_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_03615</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061601.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03615"/>
    <dbReference type="EnsemblBacteria" id="KPL78990">
        <property type="protein sequence ID" value="KPL78990"/>
        <property type="gene ID" value="ADN00_03615"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.75"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000674">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036856">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016208">
        <property type="entry name" value="Ald_Oxase/xanthine_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008274">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037165">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11908">
        <property type="entry name" value="PTHR11908"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01315">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02738">
        <property type="entry name" value="Ald_Xan_dh_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01008">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54665">
        <property type="entry name" value="SSF54665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56003">
        <property type="entry name" value="SSF56003"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ald_Xan_dh_C" evidence="1">
        <location>
            <begin position="21"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="752" mass="79581" checksum="637CF0BEC4898AF4" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAA5</accession>
    <name>A0A0P6XAA5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ABC transmembrane type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_16580</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72088">
        <property type="protein sequence ID" value="KPL72088"/>
        <property type="gene ID" value="ADN00_16580"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="27"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="101"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="178"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="240"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="292"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="97"/>
            <end position="310"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL72088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="321" mass="36024" checksum="C18DDA45F380C3C3" modified="2016-01-20" version="1">MSNISSSSLKRALGRRWNSLPSQEARLAWLLILPTALIVLGLVLFPAIFSIWISFREVGLTNLNDVFHAPFVGFENYVKVFDDFAFKAQSWRNWGAALTSIVYSFTATIVTMLIGLGAALLLNRPFRGRGLARALFLFPYIAPVVSVAFVWRWILDPTPAGVLNDILMRLDLIQIPKAYLASPGLALILVIAFQGWRYFPFAMLMILARLQAIDNTLYEAADVDGASNWQKFLFITVPELRYVLGALFLLRLMWTFNKFDDIYLLTGGGFGTKVLPVLTYEFSFRLHDFGRGSASAMILLAILVVFILVYAQTVMRGGEES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAB1</accession>
    <name>A0A0P6XAB1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Dihydrolipoyllysine-residue acetyltransferase</fullName>
            <ecNumber evidence="3">2.3.1.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_03815</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + acetyl-CoA = (R)-N(6)-(S(8)-acetyldihydrolipoyl)-L-lysyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:17017"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:10478"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="ChEBI" id="CHEBI:83111"/>
            <dbReference type="EC" id="2.3.1.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.12" evidence="3"/>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061638.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03815"/>
    <dbReference type="EnsemblBacteria" id="KPL79027">
        <property type="protein sequence ID" value="KPL79027"/>
        <property type="gene ID" value="ADN00_03815"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045254">
        <property type="term" value="C:pyruvate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006086">
        <property type="term" value="P:acetyl-CoA biosynthetic process from pyruvate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045257">
        <property type="entry name" value="E2/Pdx1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23151">
        <property type="entry name" value="PTHR23151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="4">
        <location>
            <begin position="2"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL79027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="81" mass="8647" checksum="86698464485BA6F4" modified="2016-01-20" version="1">MEMQVRMPAFGPKTEKGTLTEWLVKEGQQVRAGDALAELEADKQAHTLSAPLDGVIAELTVEDVPCEVAVGAVLCVIRVGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAN3</accession>
    <name>A0A0P6XAN3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77270.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77270">
        <property type="protein sequence ID" value="KPL77270"/>
        <property type="gene ID" value="ADN00_09020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="152"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77270.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="183" mass="20997" checksum="5F8EA3CB198AEEA0" modified="2016-01-20" version="1">MRHDLIAMLQRMQTTSAPAYRRLPIFAAGVFLFMQAALNLLMFPLLIGLQMQTFSISITEIYDDLTQPGSQILSALNRPAADHLTFLFNSQTVTIPKAQVLSALFIPFAFFAVPIVLTFWLRRRRAWTMALMLQVLILTLCMYLHFNHPAEYLYPLMAASVFQVVYLNLYDIRAAFQQLMANK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAP4</accession>
    <name>A0A0P6XAP4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">XRE family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09085</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062680.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09085"/>
    <dbReference type="EnsemblBacteria" id="KPL77279">
        <property type="protein sequence ID" value="KPL77279"/>
        <property type="gene ID" value="ADN00_09085"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00093">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01381">
        <property type="entry name" value="HTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00530">
        <property type="entry name" value="HTH_XRE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="10"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="76" mass="8645" checksum="075728C9B0FCB34D" modified="2016-01-20" version="1">MEKRKVRNNIRKLRFLHNEMTQEQLAEAVGVTRQTINAIESAKYAPSLELAFRIALVFGAPLEEVFSYTSEEDSTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBB4</accession>
    <name>A0A0P6XBB4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01840</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000007">
        <property type="protein sequence ID" value="KPL80036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061259.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000007.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80036">
        <property type="protein sequence ID" value="KPL80036"/>
        <property type="gene ID" value="ADN00_01840"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013784">
        <property type="entry name" value="Carb-bd-like_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49452">
        <property type="entry name" value="SSF49452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="148" mass="15344" checksum="E9D4CF227D5C38E0" modified="2016-01-20" version="1">MSLDNSPSLKDFANGLPASPPPDSVTRKRRLRLVIVVLAVVALLFGAINFFSSSTGSILRGVGSLQGRVTDARGNPLAQAEIYWIPAGASTFTAADGSFILNSVPAGENSLVAAYKGTGSEILVNLQPGQTVDVGTITVVVMETPEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XCA8</accession>
    <name>A0A0P6XCA8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_08325</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062523.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08325"/>
    <dbReference type="EnsemblBacteria" id="KPL77873">
        <property type="protein sequence ID" value="KPL77873"/>
        <property type="gene ID" value="ADN00_08325"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.667"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022791">
        <property type="entry name" value="L-PG_synthase/AglD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03706">
        <property type="entry name" value="LPG_synthase_TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00374">
        <property type="entry name" value="TIGR00374"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="128"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="155"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="217"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="257"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="292"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL77873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="339" mass="37068" checksum="0679B193231F475C" modified="2016-01-20" version="1">MSSSKGAMIRKAGRWLPGVFISVVLLVVVFRVAEWNDLGDAFTYIRWPYIAAALALTLASLLTKSAAWRTLLDNAPGYWQTFFIVNEGYFLNNILPFRAGEVGRAIFMGQSSKKGTMHVISTIVIERAFDVAMAASLLLATLPLTLGMAEAKSAAVTTIILVVAGFGALFLMARFNEQVKDLVNRVGGRWPLVQKWIVPRIDSLLDGLKVLTRPSQFFAAVAWSLVTWVFWVGIYYVMLLSIAPNAPLWWGAFVDSFLAMGMAIPSAPAGLGVFEASIVFALSLLKVDAAKALAYAISLHFMQFVTTAIFGLIGLLREGRSISALFEGMEKKEQPDTIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDE1</accession>
    <name>A0A0P6XDE1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase_M28 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_01040</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000003">
        <property type="protein sequence ID" value="KPL80809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061108.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01040"/>
    <dbReference type="EnsemblBacteria" id="KPL80809">
        <property type="protein sequence ID" value="KPL80809"/>
        <property type="gene ID" value="ADN00_01040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1952"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045175">
        <property type="entry name" value="M28_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007484">
        <property type="entry name" value="Peptidase_M28"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12147">
        <property type="entry name" value="PTHR12147"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04389">
        <property type="entry name" value="Peptidase_M28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M28" evidence="2">
        <location>
            <begin position="174"/>
            <end position="377"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL80809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="387" mass="41627" checksum="EF1D9A46B6275E69" modified="2016-01-20" version="1">MLFPVESNRPPHPYQSKKKLFFVPIALVLLLIGLAVISCSRQPQPQNAYPTAGRLVITQQFRPTATRIPIDHKAEKEHIATLHAAHAATPQPPGLPGVEQLSAQVNLERMLADLTWLAADARQGRLAGTPSEDEVGQWLVERMVALGLQPFTDAGFDQYLQPFDSAIPGQQAENVIAVLPAGQQPPAGYLIIGAHYDHIGVSPQGQVFNGADDDASGVIVVLETARILSESGISPRASIVFVLFSSEESGLLGSEAFARQLSEAGLVEKSAFINLEMLGAVKGTDTFIDLWDQDNTISDPLAEVVLAAGQQMSIPIQHLGVDPGSDAWQMLAYGIPSITLSTAWEDGANHPYYHSPADDVENIEPQGLLDAAKIILASAWRIAYDTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDP7</accession>
    <name>A0A0P6XDP7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ABC transmembrane type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_07775</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78340.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062412.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07775"/>
    <dbReference type="EnsemblBacteria" id="KPL78340">
        <property type="protein sequence ID" value="KPL78340"/>
        <property type="gene ID" value="ADN00_07775"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3388"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="48"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="73"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="96"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="140"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="220"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="251"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="93"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL78340.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="281" mass="30298" checksum="27B225C12BB7E668" modified="2016-01-20" version="1">MFEFPEFIYLPLDRWTSALVDWLTVNGEAFFDVVGDVLLSPMLGLEQFLLWIPWWVIILAAAGLAWKQKGWRMALGVTAGLFFIGTLGLWDMAMKTLAIVIAAALLALMIGVPIGIGMARSEKMRGIVRPILDMMQTMPSFVYLIPALMLFGLGKVPALLSTLIYAIPPVIRLTDLGIRQVPADVIEASRAFGATGRQMLLKVQLPLAAPTIMTGVNQTIMMALAMVVIASMIGAGGLGTEVLNGIARLDVGRGFNGGISIVVMAIIIDRLTQSAAQPRTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDR4</accession>
    <name>A0A0P6XDR4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CheW-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_07555</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07555"/>
    <dbReference type="EnsemblBacteria" id="KPL78358">
        <property type="protein sequence ID" value="KPL78358"/>
        <property type="gene ID" value="ADN00_07555"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3338"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039315">
        <property type="entry name" value="CheW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036061">
        <property type="entry name" value="CheW-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002545">
        <property type="entry name" value="CheW-lke_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22617">
        <property type="entry name" value="PTHR22617"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01584">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00260">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50341">
        <property type="entry name" value="SSF50341"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50851">
        <property type="entry name" value="CHEW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CheW-like" evidence="1">
        <location>
            <begin position="9"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78358.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="153" mass="16515" checksum="4A4ADACD2A268C69" modified="2016-01-20" version="1">MSSQLDDAVEQLVIFSLANEFFGLKIDKVDGIIKPQAITPVPHTKKHIIGVTNLRGTVLPVIDLRLRFGLHSASLDDNTRVVVIKAGDLNAGLMVDEVTQVAQIPLSAIDLTPQITVSLDSNYVRGLAKTDERIVILLDLEKVLAASAPRQAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XEW4</accession>
    <name>A0A0P6XEW4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_05640</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061994.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78724">
        <property type="protein sequence ID" value="KPL78724"/>
        <property type="gene ID" value="ADN00_05640"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="62" mass="6618" checksum="0E44C74EE030BF80" modified="2016-01-20" version="1">MNMVVVGLNGSDGAIQSIMQGEVKAASLQPVAERACMTSQFAPNDNAGPCQSSCWKQYHYPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XF76</accession>
    <name>A0A0P6XF76_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peptide ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_06395</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062130.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06395"/>
    <dbReference type="EnsemblBacteria" id="KPL78843">
        <property type="protein sequence ID" value="KPL78843"/>
        <property type="gene ID" value="ADN00_06395"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1782"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="6"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="42"/>
            <end position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL78843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="329" mass="36278" checksum="145F70D8B17E21A0" modified="2016-01-20" version="1">MEDTILEVKDLRTHFFTDEGVAAAVDGVSFSLSRGKTLGIVGESGCGKSVTSLSILRLVEEPAGKIIGGEIIFKDQDLLKLSEEEMRDIRGNEISMIFQEPMTSLNPVFTVGDQIAEVLRLHQGLSKNDAIQKSIEMLRLVGIPLPERRVQEYPHQLSGGMRQRVMIAMALSCNPALLIADEPTTALDVTIQAQILELMKDLKDKLGTAIMMITHDLGVVAEVADEVMIMYAGKVVEHGPVQAVFSNPLHPYTEGLMNSIPDITLDLEALETIEGLVPSIYAMPKGCRFHPRCKYAMDICKDTQPGLVSHEDRKVRCFRYSPITEEAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XFQ8</accession>
    <name>A0A0P6XFQ8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Beta-glucosidase</fullName>
            <ecNumber evidence="3 11">3.2.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">ADN00_03755</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>Hydrolysis of terminal, non-reducing beta-D-glucosyl residues with release of beta-D-glucose.</text>
            <dbReference type="EC" id="3.2.1.21"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the glycosyl hydrolase 1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.21" evidence="3 11"/>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061626.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="SMR" id="A0A0P6XFQ8"/>
    <dbReference type="STRING" id="1134406.ADN00_03755"/>
    <dbReference type="EnsemblBacteria" id="KPL79016">
        <property type="protein sequence ID" value="KPL79016"/>
        <property type="gene ID" value="ADN00_03755"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.104"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008422">
        <property type="term" value="F:beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102483">
        <property type="term" value="F:scopolin beta-glucosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030245">
        <property type="term" value="P:cellulose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001360">
        <property type="entry name" value="Glyco_hydro_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018120">
        <property type="entry name" value="Glyco_hydro_1_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017736">
        <property type="entry name" value="Glyco_hydro_1_beta-glucosidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033132">
        <property type="entry name" value="Glyco_hydro_1_N_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10353">
        <property type="entry name" value="PTHR10353"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00232">
        <property type="entry name" value="Glyco_hydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00131">
        <property type="entry name" value="GLHYDRLASE1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03356">
        <property type="entry name" value="BGL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00572">
        <property type="entry name" value="GLYCOSYL_HYDROL_F1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00653">
        <property type="entry name" value="GLYCOSYL_HYDROL_F1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="4" id="KW-0136">Cellulose degradation</keyword>
    <keyword evidence="6 11" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0624">Polysaccharide degradation</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="408"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="167"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8 10">
        <location>
            <position position="354"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="21"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="296"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="401"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010838"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR617736-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR617736-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KPL79016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="444" mass="51013" checksum="992A2CBEB86E31ED" modified="2016-01-20" version="1">MPKRSDFPKDFLWGVSTSAYQIEGAAREDGRGESIWDRFSHTPGKTRDGHTGDIACDHYHRYREDVQLMRDLGVNTYRFSLSWPRLIPTGDGPLNPQGVDFYDRLIDSLLEAGIQPFLTLYHWDLPQTLQERGGWENRQTAFDFARYASLAASRFGDRVESWITHNEPWCSAFLGYQIGLFAPGYQNLKAALQVSHHLLLSHGLAVKEIRAACSRPVEVGAALNHNPAYPYTNDPADVDAARRFDGYFNRWFLDPLAGQGYPADMLAYYADDAPEIQPGDLDIIAEPCDFLGINYYEREWVQDAPANLPPQTRRHTDPARPHTADREVYPEGLFELLQRIQRDYPKLSPIYITENGANFPDQIAPDGRVRDPQRQQYLEAHLDQALRAIQAGIDLRGYYLWSLLDNFEWALGYHGRYGIVYVDFDTQQRTPKDSARWFQQFLRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XH32</accession>
    <name>A0A0P6XH32_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Nitroreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_02915</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the flavin oxidoreductase frp family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000013">
        <property type="protein sequence ID" value="KPL79409.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061474.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000013.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02915"/>
    <dbReference type="EnsemblBacteria" id="KPL79409">
        <property type="protein sequence ID" value="KPL79409"/>
        <property type="gene ID" value="ADN00_02915"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2218"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.109.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016446">
        <property type="entry name" value="Flavin_OxRdtase_Frp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029479">
        <property type="entry name" value="Nitroreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000415">
        <property type="entry name" value="Nitroreductase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43425">
        <property type="entry name" value="PTHR43425"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00881">
        <property type="entry name" value="Nitroreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005426">
        <property type="entry name" value="Frp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55469">
        <property type="entry name" value="SSF55469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0288">FMN</keyword>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="2 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitroreductase" evidence="4">
        <location>
            <begin position="10"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR005426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL79409.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="261" mass="29736" checksum="563339235DA28316" modified="2016-01-20" version="1">MNPTLDVLYQRRSVRSYRDEPLAAEHREAILQAAFRAPTAGNMMLYSIIEVEDQVLKDRLAETCDHQPFIARAPWVLVFLADYQRWMDAFAYTAAPQRAAELGLPQRAPQEGDLLLAMSDTIIAAQNAVVAAESLGVGSCYIGDILEQYEVHRQLFNLPRYALPVCMLCFGYPKREDPPALSPRFPAEYILHRDQYHRLEPQDVQAMTAPIEERYHANGNYIAGAQNLPQHVYLRKFTADFSVEMSRSARAMLRAWCGEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XHN7</accession>
    <name>A0A0P6XHN7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_03115</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000014">
        <property type="protein sequence ID" value="KPL79331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061500.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000014.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79331">
        <property type="protein sequence ID" value="KPL79331"/>
        <property type="gene ID" value="ADN00_03115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="226"/>
            <end position="248"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="252" mass="26503" checksum="8ED84933D61A29E6" modified="2016-01-20" version="1">MSVDKLIGLGIIFLSAALIFLFSVLKRPGNGLRAIPGVQRLRRAIGLAVEDGKRLHISLGKASIVSPQSASALVGLSVLERLAEVSTVSDKPPVATSGDGGLALLSQDSLRAVYRESNQLDQYNRDLGRLAGPTDFSYIAGSLPVIRGEEVYTNVLVGHFGPEAALMCEEVERVDGFSLAASDSLPAQAALFAAAQEPLIGEELFALPAYLQSGPMHQASVRAQDVVRWVLIGVLVLGSLARLALAVMGGGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XHR9</accession>
    <name>A0A0P6XHR9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_02280</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000010">
        <property type="protein sequence ID" value="KPL79647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061341.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000010.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79647">
        <property type="protein sequence ID" value="KPL79647"/>
        <property type="gene ID" value="ADN00_02280"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="137" mass="15914" checksum="094C8A09B59FB8B0" modified="2016-01-20" version="1">MKKNMFLALAFLLIVCVLISSLLRENQKDERMKLAQTLGVRLEDHPPETDFPVSYFSAQLIEGMTLDEVHNLIIGFDQVYNCSNSVEVYYYFGANENMAFRFRVFYDENLSFKRLESEDPDSSYLSIEECKTGLLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XHU5</accession>
    <name>A0A0P6XHU5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PNP_UDP_1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_02320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000010">
        <property type="protein sequence ID" value="KPL79675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02320"/>
    <dbReference type="EnsemblBacteria" id="KPL79675">
        <property type="protein sequence ID" value="KPL79675"/>
        <property type="gene ID" value="ADN00_02320"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2680"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="SSF53167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNP_UDP_1" evidence="1">
        <location>
            <begin position="27"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="309" mass="33140" checksum="D79FF24A111636B5" modified="2016-01-20" version="1">MCFCACRPQAVPQAAAPSPPRLDDTPRIAVISAFELEFNALLDLASPDKAYEMQGRLVYTAELGGQPVVLAASGVSMVNAAMTTQWLLDHFDIQAVVVSGIAGGANPQLAVGDVVVPARWAQYQEAVFARETGDGWDTAWYGDDYGNFGMIFPQPVEAHSPEGQKSIFWFDVDPALLEAARQAAETVNLDRCTYLVVCLEEEPRVEIGGSGVSGQAFINNKSYREWVWNSLAASAMDMESAAVAQVAYSNQVPFIAFRALSDLAGGEEGDNQMLLYMKLAAKNSASLVEQFLIAWGETQPVGVNGGGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XIG9</accession>
    <name>A0A0P6XIG9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13085</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000029">
        <property type="protein sequence ID" value="KPL75288.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL75288">
        <property type="protein sequence ID" value="KPL75288"/>
        <property type="gene ID" value="ADN00_13085"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="13"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL75288.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="65" mass="7509" checksum="5817267B28294775" modified="2016-01-20" version="1">MAILLNSIPFLDLFSGTIILLALITISILVYLCGKNYLSKRNAYYDDLYKKVVKKPVEKNRKKED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XIV9</accession>
    <name>A0A0P6XIV9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_12785</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TPP enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75517.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063410.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000027.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12785"/>
    <dbReference type="EnsemblBacteria" id="KPL75517">
        <property type="protein sequence ID" value="KPL75517"/>
        <property type="gene ID" value="ADN00_12785"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012000">
        <property type="entry name" value="Thiamin_PyroP_enz_cen_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012001">
        <property type="entry name" value="Thiamin_PyroP_enz_TPP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045229">
        <property type="entry name" value="TPP_enz"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18968">
        <property type="entry name" value="PTHR18968"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00205">
        <property type="entry name" value="TPP_enzyme_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02776">
        <property type="entry name" value="TPP_enzyme_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TPP_enzyme_N" evidence="3">
        <location>
            <begin position="8"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="TPP_enzyme_M" evidence="2">
        <location>
            <begin position="172"/>
            <end position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL75517.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="480" mass="49648" checksum="26520A329A7935A8" modified="2016-01-20" version="1">MPFTNGWEAFTTALKSEKIQFVFSPPTLAGGLRAALGQEPALRLVAAAQPAQMALGCALASGEPAVCLGSLPDLLPALAQARESCAPLLAVCLDDPTGADAGGAAKWTDRVSSPQQIPWSLRRAFSLAANGQPGPVLLHLPPTVAGVQAEISAYQPAQRGIRSSGDLARVIAAAFLLVEAKNPVLLAGVGALRSNAGDDARALAELLGMPVLTTSGGRGILPEDHPLSLGWASAAAQNALQAADLVLTVGAREVEHRPGPRWIQIDIDSFELGRDWLPDLPILGDAKLVLADILSAILSEVQPKPEWQIRGAHWARVKLQSEAAALAADPPGALTPAAALSALRQAMGRETTLLYETGSPYLSALAAPHYPVDEPAGVLPLARLDWAAMQGAQAARPTWQMVAVHHTLPVGEPGPASLPAAGGLLWVALCQPGGAASPQALARLQAAGLTVERVSRAEDLPAALAALRGKAALLEITLKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XJQ8</accession>
    <name>A0A0P6XJQ8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Queuine tRNA-ribosyltransferase</fullName>
            <ecNumber evidence="4">2.4.2.29</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Guanine insertion enzyme</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA-guanine transglycosylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">tgt</name>
        <name evidence="6" type="ORF">ADN00_11705</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the base-exchange of a guanine (G) residue with the queuine precursor 7-aminomethyl-7-deazaguanine (PreQ1) at position 34 (anticodon wobble position) in tRNAs with GU(N) anticodons (tRNA-Asp, -Asn, -His and -Tyr). Catalysis occurs through a double-displacement mechanism. The nucleophile active site attacks the C1' of nucleotide 34 to detach the guanine base from the RNA, forming a covalent enzyme-RNA intermediate. The proton acceptor active site deprotonates the incoming PreQ1, allowing a nucleophilic attack on the C1' of the ribose to form the product. After dissociation, two additional enzymatic reactions on the tRNA convert PreQ1 to queuine (Q), resulting in the hypermodified nucleoside queuosine (7-(((4,5-cis-dihydroxy-2-cyclopenten-1-yl)amino)methyl)-7-deazaguanosine).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>7-aminomethyl-7-carbaguanine + guanosine(34) in tRNA = 7-aminomethyl-7-carbaguanosine(34) in tRNA + guanine</text>
            <dbReference type="Rhea" id="RHEA:24104"/>
            <dbReference type="Rhea" id="RHEA-COMP:10341"/>
            <dbReference type="Rhea" id="RHEA-COMP:10342"/>
            <dbReference type="ChEBI" id="CHEBI:16235"/>
            <dbReference type="ChEBI" id="CHEBI:58703"/>
            <dbReference type="ChEBI" id="CHEBI:74269"/>
            <dbReference type="ChEBI" id="CHEBI:82833"/>
            <dbReference type="EC" id="2.4.2.29"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="4">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4">tRNA modification; tRNA-queuosine biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer. Within each dimer, one monomer is responsible for RNA recognition and catalysis, while the other monomer binds to the replacement base PreQ1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the queuine tRNA-ribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.29" evidence="4"/>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063200.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11705"/>
    <dbReference type="EnsemblBacteria" id="KPL76020">
        <property type="protein sequence ID" value="KPL76020"/>
        <property type="gene ID" value="ADN00_11705"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3816"/>
    <dbReference type="UniPathway" id="UPA00392"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008479">
        <property type="term" value="F:queuine tRNA-ribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0101030">
        <property type="term" value="P:tRNA-guanine transglycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.105">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00168">
        <property type="entry name" value="Q_tRNA_Tgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004803">
        <property type="entry name" value="TGT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036511">
        <property type="entry name" value="TGT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002616">
        <property type="entry name" value="tRNA_ribo_trans-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01702">
        <property type="entry name" value="TGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51713">
        <property type="entry name" value="SSF51713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00430">
        <property type="entry name" value="Q_tRNA_tgt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00449">
        <property type="entry name" value="tgt_general"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 6" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 4" id="KW-0819">tRNA processing</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="TGT" evidence="5">
        <location>
            <begin position="19"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="4">
        <location>
            <begin position="97"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="RNA binding" evidence="4">
        <location>
            <begin position="250"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="RNA binding; important for wobble base 34 recognition" evidence="4">
        <location>
            <begin position="274"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="97"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4">
        <location>
            <position position="269"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="151"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="307"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="309"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="312"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="338"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01702"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL76020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="373" mass="41351" checksum="C2E14B3B4F7B09EC" modified="2016-01-20" version="1">MLSQVSPAFQFELIAQDGNARAGVFHTPHGDILTPVFAPVGTQATVKAVSSRQLTELGASLILANTYHLYLRPGSDLIAEFGGLHQFMNWHGPILTDSGGYQVFSLSSIRKVDEDGVTFRSHIDGSTHRLTPEKAISIQEQLGSDIIMAFDECPDPYDPKYNQKAMERTHRWAERCLAAQTRRDQALFGIVQGGVFPDLRARSAEFISSLGFPGHAIGGLSVGETKEEMHAMLEVVTPILPADRPRYLMGVGSPEDLVNGVLRGVDIFDCVLPTRLARHKAALTMTGRINLLNSVNTRSQSPIEEGCQCYTCQHYSRAYLRHMLVAKEILGATLISIHNLHVLLELMRQARQAIIEHRYSAFASNFLENYRLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKG3</accession>
    <name>A0A0P6XKG3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="5">PPIase</shortName>
            <ecNumber evidence="5">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_01310</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="5"/>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061243.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01310"/>
    <dbReference type="EnsemblBacteria" id="KPL80516">
        <property type="protein sequence ID" value="KPL80516"/>
        <property type="gene ID" value="ADN00_01310"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1013"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000413">
        <property type="term" value="P:protein peptidyl-prolyl isomerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024936">
        <property type="entry name" value="Cyclophilin-type_PPIase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020892">
        <property type="entry name" value="Cyclophilin-type_PPIase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044666">
        <property type="entry name" value="Cyclophilin_A-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45625">
        <property type="entry name" value="PTHR45625"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001467">
        <property type="entry name" value="Peptidylpro_ismrse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="SSF50891"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00170">
        <property type="entry name" value="CSA_PPIASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="6">
        <location>
            <begin position="29"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL80516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="162" mass="17821" checksum="86BA846CFA6B6CC3" modified="2016-01-20" version="1">MNAKQWKTPPAMQIDPAKTYRVTMKTNKGTIELDLYPEHAPKTVNNFVFLVKEGFYDGVTFHRVINNFVIQGGDPTGTGMGGPGYRFEDELVGNPLKHETGVMSMANAGPNTNGSQFFITHSPQPHLNGKHTVFGRVVNGMDVVNAIKQGDRMLEVTASEVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKH2</accession>
    <name>A0A0P6XKH2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_11170</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the MIP/aquaporin (TC 1.A.8) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063095.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11170"/>
    <dbReference type="EnsemblBacteria" id="KPL76523">
        <property type="protein sequence ID" value="KPL76523"/>
        <property type="gene ID" value="ADN00_11170"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.930"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015267">
        <property type="term" value="F:channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1080.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023271">
        <property type="entry name" value="Aquaporin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000425">
        <property type="entry name" value="MIP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00230">
        <property type="entry name" value="MIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00783">
        <property type="entry name" value="MINTRINSICP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81338">
        <property type="entry name" value="SSF81338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="81"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="140"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="174"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="222"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL76523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="250" mass="25848" checksum="D147DE9A090EF29D" modified="2016-01-20" version="1">MKPKEFIAVVVSTFVLIILGDGVVANVGLAPRLAGSAYNWNTITLGWAFAVIAAGVIAGADNNPAVTFAMAVRGQTPWSKLLPIILAEFIGAFLGAVAVYLVYRDGLIAAGMPNVWSTGPGSVFGNTFWGGDSSGALGSYSLLTACVAEFFGTVILMWGVLAVGDSRNASISNLGPFIVGGIVLVIGLCLGGPSGYSINPARDLGPRLFGLLAGTKGLFDGIYWLLPPVLIPMVAAPVGGYLYDLFFGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKI3</accession>
    <name>A0A0P6XKI3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Cysteine synthase</fullName>
            <ecNumber evidence="4 10">2.5.1.47</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">ADN00_16135</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>hydrogen sulfide + O-acetyl-L-serine = acetate + L-cysteine</text>
            <dbReference type="Rhea" id="RHEA:14829"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:58340"/>
            <dbReference type="EC" id="2.5.1.47"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 8 10">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the cysteine synthase/cystathionine beta-synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.47" evidence="4 10"/>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064072.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16135"/>
    <dbReference type="EnsemblBacteria" id="KPL72020">
        <property type="protein sequence ID" value="KPL72020"/>
        <property type="gene ID" value="ADN00_16135"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3662"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004124">
        <property type="term" value="F:cysteine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005856">
        <property type="entry name" value="Cys_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005859">
        <property type="entry name" value="CysK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001216">
        <property type="entry name" value="P-phosphate_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01139">
        <property type="entry name" value="cysK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01136">
        <property type="entry name" value="cysKM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00901">
        <property type="entry name" value="CYS_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 10" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="6 8 10" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PALP" evidence="11">
        <location>
            <begin position="8"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="8">
        <location>
            <begin position="175"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="263"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="9">
        <location>
            <position position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR605856-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR605856-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KPL72020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="298" mass="32070" checksum="5C69156110908C3A" modified="2016-01-20" version="1">MPVSSILDVIGNVPMVILRRMSSGKVFAKAEFLNPGGSIKDRVAKFILDKAVEEGRLRPGMVVIEATSGNTGIGLCLAGVQSGFAVVCVMPDNVSEERKRIIEALGGETILIPAKENLSGCVKKMQEMAKLEPDKYFVVNQFQNPDNTRAHYLQTGPEIWQDTGGEIDIFVAGIGSGGTLQGVGQYLKDQKPEIKIAAVEPRNATSLLGREPGLHQIQGIGDGFVPEVLDVGLIDMVFSVSDKDAIDTTRRLAREEGLLVGTSSGANIFAALQMDNGKNRIVTVLPDRAERYFSTALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XL74</accession>
    <name>A0A0P6XL74_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Nitroreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_10340</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062924.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76971">
        <property type="protein sequence ID" value="KPL76971"/>
        <property type="gene ID" value="ADN00_10340"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2534"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.109.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029479">
        <property type="entry name" value="Nitroreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000415">
        <property type="entry name" value="Nitroreductase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13187">
        <property type="entry name" value="Fer4_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00881">
        <property type="entry name" value="Nitroreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55469">
        <property type="entry name" value="SSF55469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="230"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="12"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="5">
        <location>
            <begin position="41"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL76971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="305" mass="34029" checksum="DBD1C2DD91721299" modified="2016-01-20" version="1">MAIKTSRAEGVAEVRIDDEKCSGCGLCVKVCKGAPLIMREGKPFVDQTRLFGCIACGKCVVVCPEDAITVEGRDLFAADVLPIAPREQRASYAQLHNLMLARRSTREFSSRPVERELVDQIIEAAASAPMGLPPSDVSALVLHGRGRVRELRDAMMVDLKKIKPFVTRTSLSLMRPFMKREEFESFDTFIVPTMDTFLQMEAEGADWWLYDAPLAVYFYCSPYSDPADPFIAATYAMLAGEALGLGSIMIGTAGYFFKYSRRLRQQFNIPHNAQQGLMVLFGHPAVKYRKAIRRRLARVEVLGEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XL94</accession>
    <name>A0A0P6XL94_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Peptidase S58</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_00560</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S58 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061098.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00560"/>
    <dbReference type="EnsemblBacteria" id="KPL81059">
        <property type="protein sequence ID" value="KPL81059"/>
        <property type="gene ID" value="ADN00_00560"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3507"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016117">
        <property type="entry name" value="ArgJ-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005321">
        <property type="entry name" value="Peptidase_S58_DmpA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36512">
        <property type="entry name" value="PTHR36512"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03576">
        <property type="entry name" value="Peptidase_S58"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56266">
        <property type="entry name" value="SSF56266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL81059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="331" mass="34063" checksum="300FD30FD779B4AB" modified="2016-01-20" version="1">MENDTLTAIPGIKVGHAQNETAITGCTVILCEKGAIAGVDQRGGAPGTRETDLLRPMHLVEKVHAIMLAGGSAFGLDAASGAMRFLEEKGVGVNIGVARVPIVPAAILLDLAIGDPSIRPDAKMGYAACQAASEKAVDQGNFGAGMGATVGKMLGHDQAMKSGIGSACIDLGNGLMVGALIAVNAFGDVVDPHTNQIIAGARTLKKGPVQVGKEDYFADTLFTMRTFAGKSILQIAGSQNTVIGVIATNAKLNKEEANKVAQMAHNGLARTIRPAHTMFDGDTIFCLATGQKNADVNLIGAYAVEAVCQAIVNAVKYAEPMGGLPSAKTRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XLD2</accession>
    <name>A0A0P6XLD2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SBP_bac_5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_10820</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial solute-binding protein 5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063011.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10820"/>
    <dbReference type="EnsemblBacteria" id="KPL77044">
        <property type="protein sequence ID" value="KPL77044"/>
        <property type="gene ID" value="ADN00_10820"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023765">
        <property type="entry name" value="SBP_5_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002741">
        <property type="entry name" value="MppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01040">
        <property type="entry name" value="SBP_BACTERIAL_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133114" description="SBP_bac_5 domain-containing protein" evidence="3">
        <location>
            <begin position="22"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="domain" description="SBP_bac_5" evidence="4">
        <location>
            <begin position="82"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL77044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="602" mass="66401" checksum="43FA17390412AC0F" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XLI7</accession>
    <name>A0A0P6XLI7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_11565</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL75996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063174.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL75996">
        <property type="protein sequence ID" value="KPL75996"/>
        <property type="gene ID" value="ADN00_11565"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="165"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="110"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL75996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="188" mass="19462" checksum="FBA6E3792B9608B9" modified="2016-01-20" version="1">MFTPVMFIQFGGAVVLILLGAWVIIQGVNLITEFYPRTLELTPQVMRRGAAAQPVPPRATFLASLDELISAEIRAINLAPQTRLQSEAAADEEHPAALSGAGDPPEDADILPVEPAPPAGEQPAAPPADSSAQHGKPPAPTDRIEAIARIVEALPSILNANFGPAAVLCLVGLALCAGGFVLILNLGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XLN7</accession>
    <name>A0A0P6XLN7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_12030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063261.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12030"/>
    <dbReference type="EnsemblBacteria" id="KPL76069">
        <property type="protein sequence ID" value="KPL76069"/>
        <property type="gene ID" value="ADN00_12030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043148">
        <property type="entry name" value="TagF_C"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="484" mass="55074" checksum="BD0117D9FEE45AD8" modified="2016-01-20" version="1">MAKQTVFISADHGLAIVYFLQSDVVPTLLDAGVEVVILTDDGLKEQIEQRFGREGLHIEGLRLGEARKYYDTVSPTQQWWLNFLRRVGSSNRINTEAMDSHIRQVDAEAVGKRKLLMPFMKVAISILRRSKTARQWLVRQQYAFSPDLYTDLFEKYQPSLVLASTPGWRYDRYLLRQAARRGVKTAAVVVGWDNPSSYSLPGAPMDWITCWSEEQKRELILGSDWEAERVHVGGIPSYDGYFRREWLMDRDEYFKLHNLDPNRKLLGYACSFITFSPNYQNVEAIARLVAEDKLSQPSQLLVRLHPNHFMDEPLFAGEREKIRQLAREVPNVHVVEPVPLGGSLGYYSGEDMPEKTSMMAYSDVFLTVYSTMVVEAAIHERPILAVCIDAPGGWNTPGRFDLPLTEIGNWPTHQRFRQAGAGRVATNATQLQQAINLYLEQPTVDLEACRKFIRDEVTYTDAQAGKRTGQFILSCLEKSQGSGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XPW9</accession>
    <name>A0A0P6XPW9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">2-hydroxy-acid oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78753.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062025.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05810"/>
    <dbReference type="EnsemblBacteria" id="KPL78753">
        <property type="protein sequence ID" value="KPL78753"/>
        <property type="gene ID" value="ADN00_05810"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.45.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-linked_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016171">
        <property type="entry name" value="Vanillyl_alc_oxidase_C-sub2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="SSF55103"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="1">
        <location>
            <begin position="41"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78753.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="464" mass="50554" checksum="6BCDE582C1D1550B" modified="2016-01-20" version="1">MVYKKIDSADVAVLQQICGGEYVKAGDAINEDFSHDELSGIHVFPEVLVEPANTEQVSAIMRYAHQQNIPVTPRGQGTGLVGGSVAVNGGIMLSLCRMNRIVELDPSTMTLTVEPGVLLMDIYKYVEPLGLFYPADPGEKSATIGGNINTNAGGMRAVKYGVTRDYVRGLEVVLADGSILMLNGKNAKNSSGYSLKDLVIGSEGTLAIVTKAILKLIPLPTRVVSLLVPFPDLSTAIRAVPEVARLKAMPTSIEFMEKQVIIAAEEYLGKKFPDKSADAFLLLTFDGNQKEAIEAAYTEAAETCLAAGAIDAFIADTLERRDAIWTARGAFLEAIKASTTEMDECDVVVPRDRIAAFVEYTRELQNELKVRIRSFGHAGDGNMHIYVLRDDLDEKTWQSILAQAFERLYQRARQYGGQVSGEHGIGFAKKSYLAESLGETTIGLMRGIKHVFDPKNILNPDKIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQ51</accession>
    <name>A0A0P6XQ51_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">FGE-sulfatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_17255</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17255"/>
    <dbReference type="EnsemblBacteria" id="KPL71491">
        <property type="protein sequence ID" value="KPL71491"/>
        <property type="gene ID" value="ADN00_17255"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016187">
        <property type="entry name" value="CTDL_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005532">
        <property type="entry name" value="SUMF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042095">
        <property type="entry name" value="SUMF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03781">
        <property type="entry name" value="FGE-sulfatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56436">
        <property type="entry name" value="SSF56436"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FGE-sulfatase" evidence="1">
        <location>
            <begin position="7"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL71491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="255" mass="29227" checksum="B3AF3A737F1DA17A" modified="2016-01-20" version="1">MEDTGMLPQMILIPAGEFIMGTSERQIRELLGKEDWALEWYEKDMFQIEQPQHRLNLPDYWIGRTPVTNVEYYKFTFETGHRVPRDWVGFHFKMETDDLPVTGISKADAEAYCAWVSKRTNKRYRLPTEPEWEKAARGTDGRIYPWGGMFNPWRCNTLESGKNATSEVGVYSPAGDSPYGCADVVGNVWEWTSTALKPYPYDSDDGREQPARSDKIVVRGGAWYYSRKLARCAAREGVLADYISPALGFRVVLEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XRE3</accession>
    <name>A0A0P6XRE3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MFS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_02750</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000013">
        <property type="protein sequence ID" value="KPL79375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061431.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000013.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79375">
        <property type="protein sequence ID" value="KPL79375"/>
        <property type="gene ID" value="ADN00_02750"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2183"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001958">
        <property type="entry name" value="Tet-R_TetA/multi-R_MdtG"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01035">
        <property type="entry name" value="TCRTETA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="16"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="82"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="106"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="141"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="167"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="209"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="255"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="285"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="308"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="347"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="374"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="15"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL79375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="414" mass="45217" checksum="8F5D6006949AE1A9" modified="2016-01-20" version="1">MIGTLQRTFREYPKKFWIVVGVSFIDHIGGTLLFPFFSLYITQKFGVGMTQAGMVLGLFSIFGLLGGFIGGALTDKFGRRKLILFGLIFSALSTLSLGLVNEFSMLIPLAVVIGLLSDMAGPAHSAMIADILPENQRQEGFGILRVVSNMSWIIGPTIGGIVANQSFFALFVIDAAVSCLVALLFFLFMPETKPQSSEESQRESMLDTFKGYAVALRDFAFMAFLFAGILMGLVYQQLYNSLSVYLRDQHGIDPQGYGFLLTASAVVVILFQFSISRWMKYRPPFAMMAAGTLFYMVGFGMFGVVSHYVLFVLAVMIITLGEMLVVPTSQALAANFAPEEMRGRYMAVFGLMWMLPATIGPGMAGVILDNYNPNLLWYIGAVLCAAAALAFYALHVRLGAQARFAPAEQESAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XSD9</accession>
    <name>A0A0P6XSD9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF2154 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_02290</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000010">
        <property type="protein sequence ID" value="KPL79649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061343.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000010.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02290"/>
    <dbReference type="EnsemblBacteria" id="KPL79649">
        <property type="protein sequence ID" value="KPL79649"/>
        <property type="gene ID" value="ADN00_02290"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024425">
        <property type="entry name" value="DUF2154"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09922">
        <property type="entry name" value="DUF2154"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="30"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="domain" description="DUF2154" evidence="2">
        <location>
            <begin position="66"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="178" mass="19571" checksum="955058CB5845DE83" modified="2016-01-20" version="1">MAKKPALWVGGAMIALGIILFIGTLTRVNIWLYVWPSLIILLGVLLLVRPRMLGSQTNVDFHLLGDVNLGSDWPVHSQEIWNVIGDTVLDLSRADFPEGETNLRVMGFVGDVKVRLPEAVGVKLNATGLVVDGNLFGMKDTGIFTPVQLESDNYASAAQRVNIETGYFIHEINLERSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XT07</accession>
    <name>A0A0P6XT07_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_12360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063322.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12360"/>
    <dbReference type="EnsemblBacteria" id="KPL76125">
        <property type="protein sequence ID" value="KPL76125"/>
        <property type="gene ID" value="ADN00_12360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="16"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="182" mass="21121" checksum="22BAF22BB05944CD" modified="2016-01-20" version="1">MTASPSSHPPSFLSKIIFRSIREEDLPQLEWEGEYSHFRQVYAAAYRRSLTGHTLIWVIEIPEKQIIGQVFVQLNSDRPELADGSSRAYLYAFRIRPEYRNLGLGSIVLDLVEESMAQMGFLYLTLNVAKNNLDAQRLYRRKGYAVMAHEPGRWSYTDHQGVLRHVVEPAWRMEKKLKPPKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XTD3</accession>
    <name>A0A0P6XTD3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Clp protease ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_06955</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the ClpA/ClpB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062420.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06955"/>
    <dbReference type="EnsemblBacteria" id="KPL78345">
        <property type="protein sequence ID" value="KPL78345"/>
        <property type="gene ID" value="ADN00_06955"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3207"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036628">
        <property type="entry name" value="Clp_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004176">
        <property type="entry name" value="Clp_R_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018368">
        <property type="entry name" value="ClpA/B_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028299">
        <property type="entry name" value="ClpA/B_CS2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041546">
        <property type="entry name" value="ClpA/ClpB_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17871">
        <property type="entry name" value="AAA_lid_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02861">
        <property type="entry name" value="Clp_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81923">
        <property type="entry name" value="SSF81923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51903">
        <property type="entry name" value="CLP_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00870">
        <property type="entry name" value="CLPAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00871">
        <property type="entry name" value="CLPAB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0143">Chaperone</keyword>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Clp R" evidence="8">
        <location>
            <begin position="3"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="425"/>
            <end position="455"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL78345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="821" mass="92613" checksum="DDD5406733956772" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XTK9</accession>
    <name>A0A0P6XTK9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_11270</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063114.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11270"/>
    <dbReference type="EnsemblBacteria" id="KPL76536">
        <property type="protein sequence ID" value="KPL76536"/>
        <property type="gene ID" value="ADN00_11270"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.952"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_supfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="SSF50998"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133219" evidence="3">
        <location>
            <begin position="23"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="338"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="22"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="30"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL76536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="373" mass="38960" checksum="3AE1EA975A4C24EA" modified="2016-01-20" version="1">MNLWLVLVMLLAAGCTLPGAGATPSAAPSALPTSAPPTPTPLPAPPLPTAAPTEAASPAPTLAPKNPSVITLQNAASLTQTALVEAASPYRLAWSADSARLGVLTLSGLELLDGKTLQTLANVQIQDPYFLLSFSPQANLMAVTADMLTIELRDVYSGEVLKTIERATPAYFTEFSPDGTRLAVGSTDQFAVEMWSVDTAVLEKTLSGFTTAAPVYAATFSADGKFLIWYARASVQVMHIASGQLGPALSHEDFVSGLALAPDDRLLAAGVAAQIGEDYTPIIQLWDSNAGQAVGRLVSSQGVPVSLSFSPDGSLLAAGAAREVVLWDVQNQREVTRLRGFNDALNAVVFSPDGKTLATSASDGTVRLWQVLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUK1</accession>
    <name>A0A0P6XUK1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Dihydroorotate dehydrogenase</fullName>
            <shortName evidence="9">DHOD</shortName>
            <shortName evidence="9">DHODase</shortName>
            <shortName evidence="9">DHOdehase</shortName>
            <ecNumber evidence="9">1.3.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">pyrD</name>
        <name evidence="11" type="ORF">ADN00_06325</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the conversion of dihydroorotate to orotate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>(S)-dihydroorotate + A = AH2 + orotate</text>
            <dbReference type="Rhea" id="RHEA:18073"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
            <dbReference type="ChEBI" id="CHEBI:30864"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="9">Binds 1 FMN per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Pyrimidine metabolism; UMP biosynthesis via de novo pathway.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the dihydroorotate dehydrogenase family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.-.-" evidence="9"/>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062117.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06325"/>
    <dbReference type="EnsemblBacteria" id="KPL78830">
        <property type="protein sequence ID" value="KPL78830"/>
        <property type="gene ID" value="ADN00_06325"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00070"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004152">
        <property type="term" value="F:dihydroorotate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd04740">
        <property type="entry name" value="DHOD_1B_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00224">
        <property type="entry name" value="DHO_dh_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033888">
        <property type="entry name" value="DHOD_1B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005720">
        <property type="entry name" value="Dihydroorotate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024920">
        <property type="entry name" value="Dihydroorotate_DH_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012135">
        <property type="entry name" value="Dihydroorotate_DH_1_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001295">
        <property type="entry name" value="Dihydroorotate_DH_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01180">
        <property type="entry name" value="DHO_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000164">
        <property type="entry name" value="DHO_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01037">
        <property type="entry name" value="pyrD_sub1_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00912">
        <property type="entry name" value="DHODEHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 9" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 9" id="KW-0288">FMN</keyword>
    <keyword evidence="8 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7 9" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHO_dh" evidence="10">
        <location>
            <begin position="5"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="69"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="195"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="9">
        <location>
            <position position="132"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="21"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="45"/>
            <end position="46"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="129"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="194"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="220"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="246"/>
            <end position="247"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="268"/>
            <end position="269"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL78830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="307" mass="31222" checksum="8B991656EEEB0B01" modified="2016-01-20" version="1">MTDLSCAFLNLHLKNPTVLASGILGTSPTLLERVARAGAGAVTSKSCGPEPRAGHPNPVCLDWGGGLINAIGLTNPGIEEETRHLTASAQRLRPLGVPLIASIFAPSVEAFAEVARKVSAALPDLIEVNISCPNVGDEFGTPFAGLPETAAAVTAAVKAATDIPISVKLAPNVPVIARIARAVVEAGADAITAVNTMPGMVIDADAGRPVLANKMGGISGPALKPIALRCVAEIARAVKVPIIGTGGITTGRDAAEMIMAGASAVGIGSAAWYRGPEVFDAIVSELAEWMQAAGYSSIEEMRGIAIQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUT5</accession>
    <name>A0A0P6XUT5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">PMT_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ADN00_03360</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78949.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061550.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03360"/>
    <dbReference type="EnsemblBacteria" id="KPL78949">
        <property type="protein sequence ID" value="KPL78949"/>
        <property type="gene ID" value="ADN00_03360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038731">
        <property type="entry name" value="RgtA/B/C-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13231">
        <property type="entry name" value="PMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="40"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="78"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="142"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="298"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="333"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="412"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="441"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="471"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="500"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="domain" description="PMT_2" evidence="9">
        <location>
            <begin position="220"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL78949.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="663" mass="73522" checksum="266EB956E0B91308" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XVD7</accession>
    <name>A0A0P6XVD7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05065</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061867.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79214">
        <property type="protein sequence ID" value="KPL79214"/>
        <property type="gene ID" value="ADN00_05065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="142" mass="16515" checksum="957E297B22A2D344" modified="2016-01-20" version="1">MIRLALQKDVSQIYQLMKRVPGFWRDDWRDDVVERGIDVSDGLAFVWEEEKQIKGFVCAHDLGFRCYMSALVVSPDVQGRSIGTHLVRYVERELCARGCTVLIADVWNEAESYFFKELGWVRPTSVLMQQNLFGRDMDCDDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XZ25</accession>
    <name>A0A0P6XZ25_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cell shape-determining protein MreB</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">mreB</name>
        <name evidence="3" type="ORF">ADN00_13855</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Forms membrane-associated dynamic filaments that are essential for cell shape determination. Acts by regulating cell wall synthesis and cell elongation, and thus cell shape. A feedback loop between cell geometry and MreB localization may maintain elongated cell shape by targeting cell wall growth to regions of negative cell wall curvature.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Forms polymers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="2">Membrane-associated.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the FtsA/MreB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74371.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063616.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000032.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13855"/>
    <dbReference type="EnsemblBacteria" id="KPL74371">
        <property type="protein sequence ID" value="KPL74371"/>
        <property type="gene ID" value="ADN00_13855"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000902">
        <property type="term" value="P:cell morphogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd10225">
        <property type="entry name" value="MreB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02207">
        <property type="entry name" value="MreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004753">
        <property type="entry name" value="MreB"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01652">
        <property type="entry name" value="SHAPEPROTEIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0133">Cell shape</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="157"/>
            <end position="159"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="205"/>
            <end position="208"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL74371.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="335" mass="35789" checksum="4F92AB8EBB152F78" modified="2016-01-20" version="1">MPFLTREFGIDLGTTHITVAEGNQILVREPTVVAIIVDEQKMVEWGQAAKDMLGRVPDSIEVVRPLQHGVIAEYDVTETLLSFLVKKLSGPMLLARPRLMLTVPFGVTSVESRAVQEAGLGARSREVYLIQQPLAAALGVDLPIGTPSGNMILSLGGGTSQAAVLAMNGIVTAETSRTGGIKLDEAIIGYVRKKYGLIIGQPTAEQLKIRIGAALPQDTQDVMEIQGQDQVSGLPRPLTLTTDDIIDALQEPLGEIVQTARRVLEKTPPELISDIIDRGVALTGGGAMLRGLDRFLTKSLGIPAYLVDNPTTCTAEGAARALVMRESIRRSLIAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y0A7</accession>
    <name>A0A0P6Y0A7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ANAPC4_WD40 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_05840</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78758.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78758">
        <property type="protein sequence ID" value="KPL78758"/>
        <property type="gene ID" value="ADN00_05840"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1644"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024977">
        <property type="entry name" value="Apc4_WD40_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12894">
        <property type="entry name" value="ANAPC4_WD40"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="SSF50978"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133295" description="ANAPC4_WD40 domain-containing protein" evidence="2">
        <location>
            <begin position="23"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="domain" description="ANAPC4_WD40" evidence="3">
        <location>
            <begin position="206"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="213"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL78758.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="381" mass="41193" checksum="EB9D17995AC4FF9C" modified="2016-01-20" version="1">MKHRWILVTALFLSACAQPTQTQNNPVASKPAAPMPTCTPPILPTSTVTPLPQPTSTPEPLPPAPISPKNLADLTQVYNISLADIRRVHFSQDGSQIAAATGNQENFGAFTFASPSGEPLYTYQPYDGIVWDLDISKDDLWMATAANSADGQGIAVWNLVNQTLDQKIGQPAQPDCVAFSPDGSVLAAGGLTTWPDGEIWLYEAATWTPLLNMEAPGQNILALEYSPDGSMLVSAGTDGIIRIWRSRDGSLLHTLDYAPQASRITFSPGGELLASTFCTDFDSGGCTTGGVVVWRTADWSILQVFEDLAQDVIFSPDGQLMITASGYHDPLIRFRRTIDWSEIYTISDNAQALAMNRLGNQLVVANQSGIQVWMVKPQPVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y1S2</accession>
    <name>A0A0P6Y1S2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SWIM-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_12935</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75541.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063437.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000027.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12935"/>
    <dbReference type="EnsemblBacteria" id="KPL75541">
        <property type="protein sequence ID" value="KPL75541"/>
        <property type="gene ID" value="ADN00_12935"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006259">
        <property type="term" value="P:DNA metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041247">
        <property type="entry name" value="Rad52_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042525">
        <property type="entry name" value="Rad52_Rad59_Rad22_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007527">
        <property type="entry name" value="Znf_SWIM"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04098">
        <property type="entry name" value="Rad52_Rad22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50966">
        <property type="entry name" value="ZF_SWIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="SWIM-type" evidence="3">
        <location>
            <begin position="52"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="277"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="279"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL75541.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="359" mass="39781" checksum="C8B1068F954BFCAC" modified="2016-01-20" version="1">MNDELIPRSGDPNAAQLERTERAKSAIRAGLFHISRAGPQQWTVKNGEKLPYAVSLQGDTWVCTCMDYQQRGPQILCKHIEGVRLSEAAQNEVLQANYKEQQMDQPDSNNLSERFNRILWELRQPLDMSRVKRRQAPGMGSVPYLEGYDVIDRANAIFGFAWSFDLISEPLIVRWHKKILAWNQQERRKVPVTDANGNFQTEEVGLVYITGKVTVELDGKEYSHADLGRCIFTGDTPEALDMALAGSATDCLKRCFRQLGSQFGNDLYDKEIAQTAGMETSRDGGSNTPVAAQSTHSPAASQASTNANGRKYGDGTSVNGNVSEQEAYDTYKKATGSAPDSKDSLRFWIASQRTSTVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y3A8</accession>
    <name>A0A0P6Y3A8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_02950</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000013">
        <property type="protein sequence ID" value="KPL79398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061462.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000013.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79398">
        <property type="protein sequence ID" value="KPL79398"/>
        <property type="gene ID" value="ADN00_02950"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045466">
        <property type="entry name" value="DUF6498"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20108">
        <property type="entry name" value="DUF6498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="126"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="181"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="222"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="261"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="286"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="24"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="315" mass="35093" checksum="F1C77F303847E19A" modified="2016-01-20" version="1">MPAKKLPPQYQSLVYQVKRDPANADAWEALGDRLSEAGDTRRAEECYRRVLALRPDDLEARISYQHLQTGGAGDSLNGVDALVSGLEKLSLDHLPLWFQVFLAFFSFLVTLMLARLQNWQTTDLVWSLWISSLTLGYAYLLTGIAAKALRGGMGLDASPGGKVIQELAPAPLRWSLSIGGALFTLAFFTIHFGMFHLVHSVFLNQFFPLVRESGGFPNVFEFIRVCIVNYWPVILLSALSQLPNFIRAAETQQDRMLMMPYLNVVKMHLSIFVFAGLSALQVSSAALAYLLVLYFFPFGALATLFKRPKPAPENA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y4G8</accession>
    <name>A0A0P6Y4G8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Xanthine phosphoribosyltransferase</fullName>
            <shortName evidence="1">XPRTase</shortName>
            <ecNumber evidence="1">2.4.2.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">xpt</name>
        <name evidence="3" type="ORF">ADN00_02075</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Converts the preformed base xanthine, a product of nucleic acid breakdown, to xanthosine 5'-monophosphate (XMP), so it can be reused for RNA or DNA synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>diphosphate + XMP = 5-phospho-alpha-D-ribose 1-diphosphate + xanthine</text>
            <dbReference type="Rhea" id="RHEA:10800"/>
            <dbReference type="ChEBI" id="CHEBI:17712"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="EC" id="2.4.2.22"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; XMP biosynthesis via salvage pathway; XMP from xanthine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the purine/pyrimidine phosphoribosyltransferase family. Xpt subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.22" evidence="1"/>
    <dbReference type="EMBL" id="LGCL01000008">
        <property type="protein sequence ID" value="KPL79928.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02075"/>
    <dbReference type="EnsemblBacteria" id="KPL79928">
        <property type="protein sequence ID" value="KPL79928"/>
        <property type="gene ID" value="ADN00_02075"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2846"/>
    <dbReference type="UniPathway" id="UPA00602">
        <property type="reaction ID" value="UER00658"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000310">
        <property type="term" value="F:xanthine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046110">
        <property type="term" value="P:xanthine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032265">
        <property type="term" value="P:XMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01184">
        <property type="entry name" value="XPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010079">
        <property type="entry name" value="Xanthine_PRibTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01744">
        <property type="entry name" value="XPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="1" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="2">
        <location>
            <begin position="37"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="region of interest" description="5-phospho-alpha-D-ribose 1-diphosphate binding" evidence="1">
        <location>
            <begin position="128"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="20"/>
        </location>
        <ligand>
            <name>xanthine</name>
            <dbReference type="ChEBI" id="CHEBI:17712"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>xanthine</name>
            <dbReference type="ChEBI" id="CHEBI:17712"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>xanthine</name>
            <dbReference type="ChEBI" id="CHEBI:17712"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79928.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="192" mass="20828" checksum="9BF66386DD3CA00F" modified="2016-01-20" version="1">MQLLKDRILSDGKYLGNGILKVDGFINHQVDPVLMDACGKELAECFKDSGATRVLTAEISGIAPAIMAARYLNLPVVYARKTKPVTMPNTVYLTIAPSHTKGRMVELIVSPEYLPRGEKVLIIDDFLASGETILGLVRLVEAAGCELVGVGTLIEKTFEKGRTMLEQFNVPVVSLAMISAMNEDGTIAFLDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y5N0</accession>
    <name>A0A0P6Y5N0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CIS_tube domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09905</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062840.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09905"/>
    <dbReference type="EnsemblBacteria" id="KPL76903">
        <property type="protein sequence ID" value="KPL76903"/>
        <property type="gene ID" value="ADN00_09905"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045361">
        <property type="entry name" value="CIS_tube_prot_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19266">
        <property type="entry name" value="CIS_tube"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CIS_tube" evidence="1">
        <location>
            <begin position="19"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF19266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="234" mass="26252" checksum="FF9ABE5463C97E85" modified="2016-01-20" version="1">MALEKAKLQWSSLIPPLKGEIECQFNPAELTIKKEVSWEETTIPSFNAHRLKFGGGKPATYNLSLFFDSYTTDPPKPGQDPKPPQDVREYTNQLLRLTLRGAGALPAMYLIPFASPPSVTLVWGKITLFTAVVESVQVTFTLFAQDGTPIRAKADVAFKQHELFGDDVLPAQNPTSRSDPRKTRFVHARQRLDQIAFEEYGDARYWRMLAEANGMDDPFNLADGQLLVIPQNLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y6S1</accession>
    <name>A0A0P6Y6S1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">LuxR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_00195</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061092.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00195"/>
    <dbReference type="EnsemblBacteria" id="KPL81135">
        <property type="protein sequence ID" value="KPL81135"/>
        <property type="gene ID" value="ADN00_00195"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="5"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="147"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL81135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="217" mass="23950" checksum="F2BD0C574F62A66C" modified="2016-01-20" version="1">MAKQRILLVDDHEVVRLGLKALLGHHSQFDVVGEAVNAKEAVEQVERLRPDIVLMDIRLPGASGIEACEEITHKFPETRVVMLTSYAEDEMLFSAIRAGASGYVLKQIAGDDLIRALEAVGRGEALLDTAVTQRVFQEVRRAVREEEASAFANLSQQERHVLLLVSEGKTNREIAKALFLGEGTVRNYVSSILSKLGVSNRAEAAAYAVEHNLRDYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y6X5</accession>
    <name>A0A0P6Y6X5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Aconitate hydratase</fullName>
            <shortName evidence="8">Aconitase</shortName>
            <ecNumber evidence="8">4.2.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">ADN00_09440</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the isomerization of citrate to isocitrate via cis-aconitate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 8">
            <text>citrate = D-threo-isocitrate</text>
            <dbReference type="Rhea" id="RHEA:10336"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16947"/>
            <dbReference type="EC" id="4.2.1.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <text evidence="8">Binds 1 [4Fe-4S] cluster per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Carbohydrate metabolism; tricarboxylic acid cycle; isocitrate from oxaloacetate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the aconitase/IPM isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.3" evidence="8"/>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062741.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09440"/>
    <dbReference type="EnsemblBacteria" id="KPL77333">
        <property type="protein sequence ID" value="KPL77333"/>
        <property type="gene ID" value="ADN00_09440"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4126"/>
    <dbReference type="UniPathway" id="UPA00223">
        <property type="reaction ID" value="UER00718"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003994">
        <property type="term" value="F:aconitate hydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047780">
        <property type="term" value="F:citrate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01580">
        <property type="entry name" value="AcnA_IRP_Swivel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.19.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.499.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044137">
        <property type="entry name" value="AcnA_IRP_Swivel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015931">
        <property type="entry name" value="Acnase/IPM_dHydase_lsu_aba_1/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001030">
        <property type="entry name" value="Acoase/IPM_deHydtase_lsu_aba"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015928">
        <property type="entry name" value="Aconitase/3IPM_dehydase_swvl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006249">
        <property type="entry name" value="Aconitase/IRP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018136">
        <property type="entry name" value="Aconitase_4Fe-4S_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036008">
        <property type="entry name" value="Aconitase_4Fe-4S_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000573">
        <property type="entry name" value="AconitaseA/IPMdHydase_ssu_swvl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11670">
        <property type="entry name" value="PTHR11670"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00330">
        <property type="entry name" value="Aconitase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00694">
        <property type="entry name" value="Aconitase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00415">
        <property type="entry name" value="ACONITASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53732">
        <property type="entry name" value="SSF53732"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01341">
        <property type="entry name" value="aconitase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00450">
        <property type="entry name" value="ACONITASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01244">
        <property type="entry name" value="ACONITASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5 8" id="KW-0408">Iron</keyword>
    <keyword evidence="6 8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 11" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aconitase" evidence="9">
        <location>
            <begin position="76"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="domain" description="Aconitase_C" evidence="10">
        <location>
            <begin position="699"/>
            <end position="826"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL77333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="900" mass="97697" checksum="A656F10761247905" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y8B1</accession>
    <name>A0A0P6Y8B1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Chromosome partition protein Smc</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">smc</name>
        <name evidence="5" type="ORF">ADN00_08560</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Required for chromosome condensation and partitioning.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="3">Contains large globular domains required for ATP hydrolysis at each terminus and a third globular domain forming a flexible hinge near the middle of the molecule. These domains are separated by coiled-coil structures.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SMC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062567.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08560"/>
    <dbReference type="EnsemblBacteria" id="KPL77909">
        <property type="protein sequence ID" value="KPL77909"/>
        <property type="gene ID" value="ADN00_08560"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.716"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030261">
        <property type="term" value="P:chromosome condensation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007062">
        <property type="term" value="P:sister chromatid cohesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01894">
        <property type="entry name" value="Smc_prok"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003395">
        <property type="entry name" value="RecF/RecN/SMC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024704">
        <property type="entry name" value="SMC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010935">
        <property type="entry name" value="SMC_hinge"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036277">
        <property type="entry name" value="SMC_hinge_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011890">
        <property type="entry name" value="SMC_prok"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06470">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02463">
        <property type="entry name" value="SMC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005719">
        <property type="entry name" value="SMC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00968">
        <property type="entry name" value="SMC_hinge"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75553">
        <property type="entry name" value="SSF75553"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02168">
        <property type="entry name" value="SMC_prok_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SMC hinge" evidence="4">
        <location>
            <begin position="525"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="176"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="243"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="686"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="817"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL77909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="1201" mass="136795" checksum="28455B9C877AF7A3" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YA11</accession>
    <name>A0A0P6YA11_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">E1_dh domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_05165</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061907.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05165"/>
    <dbReference type="EnsemblBacteria" id="KPL78649">
        <property type="protein sequence ID" value="KPL78649"/>
        <property type="gene ID" value="ADN00_05165"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1505"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016624">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="E1_dh" evidence="3">
        <location>
            <begin position="34"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL78649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="339" mass="37348" checksum="6FABE3EC0780374A" modified="2016-01-20" version="1">MSTNNQIYEPLSEKRRKEITKSLSKDVMVEALQKMWKIRAFEEKAEELYMLGKIHGTMHLSIGMEASAMGSILPLRQDDLILSTHRGHGHCIAKNADLKLMMAEFLGKECGYCRGRGGSMHIADVEGGNLGANGVVAGGIPMAVGVGLGLKLQKTDKVIVCFFGDGAANEGAFHEALNMAAIYDLPVVFVCENNQYGMSGSFKRMFRIPRISDRAAGYGIPGVTVDGNDLLAVYDAVNTAVDRARNQRIPTLVENITYRWRGHSKSDANRYRTKEEIEEWKTKDPNTRFADWLVESKVITSDEAEQIRQAAYAEINAAAEFAEGCADPALESIEEGVYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YAB6</accession>
    <name>A0A0P6YAB6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_05965</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062055.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05965"/>
    <dbReference type="EnsemblBacteria" id="KPL78777">
        <property type="protein sequence ID" value="KPL78777"/>
        <property type="gene ID" value="ADN00_05965"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008324">
        <property type="term" value="F:cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1450">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004680">
        <property type="entry name" value="Cit_transptr-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006037">
        <property type="entry name" value="RCK_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036721">
        <property type="entry name" value="RCK_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03600">
        <property type="entry name" value="CitMHS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02080">
        <property type="entry name" value="TrkA_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF116726">
        <property type="entry name" value="SSF116726"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51202">
        <property type="entry name" value="RCK_C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="108"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="152"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="188"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="424"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="468"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="507"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="553"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="592"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="7">
        <location>
            <begin position="231"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="domain" description="RCK C-terminal" evidence="7">
        <location>
            <begin position="322"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL78777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="615" mass="65415" checksum="67B19A1D9A3B4391" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YAW7</accession>
    <name>A0A0P6YAW7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA small subunit methyltransferase A</fullName>
            <ecNumber evidence="6">2.1.1.182</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">16S rRNA dimethyladenosine transferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">16S rRNA dimethylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">S-adenosylmethionine-6-N', N'-adenosyl(rRNA) dimethyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rsmA</name>
        <name evidence="6" type="synonym">ksgA</name>
        <name evidence="9" type="ORF">ADN00_03995</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Specifically dimethylates two adjacent adenosines (A1518 and A1519) in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>adenosine(1518)/adenosine(1519) in 16S rRNA + 4 S-adenosyl-L-methionine = 4 H(+) + N(6)-dimethyladenosine(1518)/N(6)-dimethyladenosine(1519) in 16S rRNA + 4 S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:19609"/>
            <dbReference type="Rhea" id="RHEA-COMP:10232"/>
            <dbReference type="Rhea" id="RHEA-COMP:10233"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74493"/>
            <dbReference type="EC" id="2.1.1.182"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.182" evidence="6"/>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061671.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03995"/>
    <dbReference type="EnsemblBacteria" id="KPL79052">
        <property type="protein sequence ID" value="KPL79052"/>
        <property type="gene ID" value="ADN00_03995"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.154"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052908">
        <property type="term" value="F:16S rRNA (adenine(1518)-N(6)/adenine(1519)-N(6))-dimethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00607">
        <property type="entry name" value="16SrRNA_methyltr_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001737">
        <property type="entry name" value="KsgA/Erm"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023165">
        <property type="entry name" value="rRNA_Ade_diMease-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020596">
        <property type="entry name" value="rRNA_Ade_Mease_Trfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020598">
        <property type="entry name" value="rRNA_Ade_methylase_Trfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011530">
        <property type="entry name" value="rRNA_adenine_dimethylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11727">
        <property type="entry name" value="PTHR11727"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00398">
        <property type="entry name" value="RrnaAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00650">
        <property type="entry name" value="rADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00755">
        <property type="entry name" value="ksgA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01131">
        <property type="entry name" value="RRNA_A_DIMETH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51689">
        <property type="entry name" value="SAM_RNA_A_N6_MT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6 7" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="4 6 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3 6 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="rADc" evidence="8">
        <location>
            <begin position="37"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="30"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="32"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6 7">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00650"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL79052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="286" mass="31360" checksum="CC3D71287F553AF8" modified="2016-01-20" version="1">MDSSLDIPPLNPVALLKAHQLNPKKGLGQNFLIDASALKKIVTAAEVSPDDCVLEIGPGLGSLTRYLAQSCRRLVAVELDHHLVPILREVVSPWPNVEIVEGDILQQDPVQLINEDGYLVVANIPYYITSAVIRHLLESQVKPARMVLTMQLEVAQRICAQPGDLSLLALSIQVYGAPRSVLRIPAGAFYPAPKVDSATLRVDLYPQPLIPTDQIEVFFRLAKAGFSQKRKTLRNAMSGGLALPREQVEQFLANANIDPQRRAETLSIPEWKDVTAAFINAKNPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YCA5</accession>
    <name>A0A0P6YCA5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DEDD_Tnp_IS110 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_02275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000010">
        <property type="protein sequence ID" value="KPL79646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79646">
        <property type="protein sequence ID" value="KPL79646"/>
        <property type="gene ID" value="ADN00_02275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002525">
        <property type="entry name" value="Transposase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01548">
        <property type="entry name" value="DEDD_Tnp_IS110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEDD_Tnp_IS110" evidence="1">
        <location>
            <begin position="5"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="125" mass="13920" checksum="CF3CA26AB21907E2" modified="2016-01-20" version="1" fragment="single">MTFYCGIDVAKRKHAVAILNESGQVCKPVFVTENTRAGLEYLLEHLSQLGNEVSIGLEATGHYWLSLYDVLTSQGYPVSVINPLQISAYRKSGVRKVKNDRSDAVWIADFMRISNTPASSRDIPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YEP8</accession>
    <name>A0A0P6YEP8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0047 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061215.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01620"/>
    <dbReference type="EnsemblBacteria" id="KPL80569">
        <property type="protein sequence ID" value="KPL80569"/>
        <property type="gene ID" value="ADN00_01620"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001602">
        <property type="entry name" value="UPF0047"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035917">
        <property type="entry name" value="YjbQ-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30615">
        <property type="entry name" value="PTHR30615"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01894">
        <property type="entry name" value="UPF0047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004681">
        <property type="entry name" value="UCP004681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111038">
        <property type="entry name" value="SSF111038"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00149">
        <property type="entry name" value="TIGR00149_YjbQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01314">
        <property type="entry name" value="UPF0047"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="139" mass="16026" checksum="56807FFA910430A3" modified="2016-01-20" version="1">MNWYKDTLTIRTHGKGLYPFTPLVTERLRRWGAREGLCCLYVQHTSASLVISENYDPTAKMDLETFMERLVPENQTWFRHTLEGADDSPSHIRAMLTQPSLTIPIDDGALSLGTWQGIYLFEHRNHPQARSVLLRVLDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YFP6</accession>
    <name>A0A0P6YFP6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_00255</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00255"/>
    <dbReference type="EnsemblBacteria" id="KPL81017">
        <property type="protein sequence ID" value="KPL81017"/>
        <property type="gene ID" value="ADN00_00255"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009097">
        <property type="entry name" value="Cyclic_Pdiesterase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55144">
        <property type="entry name" value="SSF55144"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL81017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="150" mass="17068" checksum="23DBD65193A92BCF" modified="2016-01-20" version="1">MDGISISPIPHFSWFVGESLLSGEVEQALIAAAKNYPPFEVNVVDIGIFTGDHPIVYLGLQKDKTLVRLHQTMRQAISQKTNGTSLFYEPDQWIPHITLAYHEHDVERLACTVRQLVFRFRPMKLSVKEIGLIYQNLDQYGVAMKYAFTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GLB1</accession>
    <name>A0A0N8GLB1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">SBP_bac_5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_16005</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial solute-binding protein 5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72002.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064045.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16005"/>
    <dbReference type="EnsemblBacteria" id="KPL72002">
        <property type="protein sequence ID" value="KPL72002"/>
        <property type="gene ID" value="ADN00_16005"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3635"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023765">
        <property type="entry name" value="SBP_5_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002741">
        <property type="entry name" value="MppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01040">
        <property type="entry name" value="SBP_BACTERIAL_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006025790" description="SBP_bac_5 domain-containing protein" evidence="4">
        <location>
            <begin position="23"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="domain" description="SBP_bac_5" evidence="5">
        <location>
            <begin position="112"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="32"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL72002.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="552" mass="60979" checksum="CDFA2BB14A2467BB" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GLE4</accession>
    <name>A0A0N8GLE4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_15730</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063983.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72266">
        <property type="protein sequence ID" value="KPL72266"/>
        <property type="gene ID" value="ADN00_15730"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="131" mass="12979" checksum="8B3304762F9CAFB6" modified="2016-01-20" version="1">MAEITKTTSKIAQVYPGKSEVLGYKTAVAVTAGQAVTLNTSGLLVVADANDAAANTFIGIALESVGAGVACPVLMAGYVSGFTVSSLNAMAPVYLSDDAGKVDTAAGTVSVVVGFVGSLPDGTKCLYVAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GLY0</accession>
    <name>A0A0N8GLY0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_14395</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FGGY kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000034">
        <property type="protein sequence ID" value="KPL73754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL73754">
        <property type="protein sequence ID" value="KPL73754"/>
        <property type="gene ID" value="ADN00_14395"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000577">
        <property type="entry name" value="Carb_kinase_FGGY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="Carb_kinase_FGGY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018483">
        <property type="entry name" value="Carb_kinase_FGGY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018484">
        <property type="entry name" value="Carb_kinase_FGGY_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02782">
        <property type="entry name" value="FGGY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00370">
        <property type="entry name" value="FGGY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000538">
        <property type="entry name" value="GlpK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00445">
        <property type="entry name" value="FGGY_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FGGY_N" evidence="2">
        <location>
            <begin position="7"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="FGGY_C" evidence="3">
        <location>
            <begin position="266"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL73754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="473" mass="51972" checksum="F0647933FAD31183" modified="2016-01-20" version="1">MLAFAGRPMTVLHPFDGACEMDMRAVWDGLVEVCQELSERAPREWQALAGVAITGQGDGMWPLDENGEPVGNAILWNDSRCKRLELQNEAEITAYGVAHSLSPLFVGAVPSILRWLMELEPQRFAKIRHALHCKDWLVYRLTGRIMTDRSDASTALMNILQDRYEFDQLELMGLPRETRQVFPEIVDSLEIVGQTSPAAEAACRLPAGLPVMAGSLDVAATTFGAGARQPGDAVTILGTTFSNQVILDASQVSHTDVAGSTLCYLYPGTFMRVMATTNGASAIEWARRTLLPQASLEEMEQGIAAAPEGCEGVFFQPYLNGERAPFRESRAAGAFHGITPRHTPQHLMRAVFEGLAYSLRHCYDHLPKGDPPVILAGGASASRAMCQICANVLNRPMLRVPDQEFGLYGMASALLEKLGYVSARGAAVQEGEFFSPQAASVRRYADGFGIYRQLRDSELEFWKARDRFLERAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GLY1</accession>
    <name>A0A0N8GLY1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">zf-HC2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_14465</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000034">
        <property type="protein sequence ID" value="KPL73762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063737.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000034.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14465"/>
    <dbReference type="EnsemblBacteria" id="KPL73762">
        <property type="protein sequence ID" value="KPL73762"/>
        <property type="gene ID" value="ADN00_14465"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041916">
        <property type="entry name" value="Anti_sigma_zinc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027383">
        <property type="entry name" value="Znf_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13490">
        <property type="entry name" value="zf-HC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="162"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="196"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="224"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="269"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="zf-HC2" evidence="2">
        <location>
            <begin position="6"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL73762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="297" mass="32395" checksum="31C4B89FEDD9DFA2" modified="2016-01-20" version="1">MNAHEKFRENLPFYVTGALDANERRALEDHLQTCAECQVDLALWRNTAQEVTEQSASLRVSDRVIESALGQIRAEQRQPGALRRAVDLLLSQIPLVRHEIWPASALIFLIGYSAAVLVKMEFLIQLIAPMVAAWGIASLYGPENDQAFELAAATPTHQAQILLARLAAVFGYNLALAVTVSLAATPFIPTLSLSGLILSWLAPMTFLAALALLLSLWMSTGSAVVIPYLLWLGKFILGNMLVGESSGPVFVGSAAEGITLFIRFWENPLLLFGLAAVLLAGALLSLRWPDRRLPRLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMB4</accession>
    <name>A0A0N8GMB4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74826.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063524.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000031.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74826">
        <property type="protein sequence ID" value="KPL74826"/>
        <property type="gene ID" value="ADN00_13380"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000639">
        <property type="entry name" value="Epox_hydrolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00111">
        <property type="entry name" value="ABHYDROLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00412">
        <property type="entry name" value="EPOXHYDRLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="25"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74826.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="279" mass="31502" checksum="E07023C88926245A" modified="2016-01-20" version="1">MNPEQTACLAGEAYARVSDGDGKPVILIHGLPSSLDEWNDFFDDLSGAGYKPMAMDLLGHGRSHRPVSARCYTVENFNAFFCHWMDSQKLAGPVTLVGHSFGGHLALRYAAEHPDRVERLVLINPFLSFDQMTLVNRLVFRFPLFAAALYSRVPAFLIRCFVWLGSLENGRFLHSSLTKADFESMLLDYHRCSPQVVYLPLSVWDEAIPYPQIQMPVLLLWGVKDMTLKVSWFERASRKMPNCQTARVAGGHYPHRSNYGEVKPVIFDFLQRSASSVEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GN37</accession>
    <name>A0A0N8GN37_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_10600</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062970.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10600"/>
    <dbReference type="EnsemblBacteria" id="KPL77010">
        <property type="protein sequence ID" value="KPL77010"/>
        <property type="gene ID" value="ADN00_10600"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="8"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="95"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="159" mass="17559" checksum="1DFB9A53A80B2913" modified="2016-01-20" version="1">MNSVSKCMKRKVVCISQDAPVREAISLVVENKVGTLPVLDEAGRLVGVVKLRHLLSLAMPNFLNFMEHFEFVHGFGAIDLRMPLPEDLNRKVREIMDEPVYAEENFSLMHAAAILNQNGLKDLPVVNLEGKLIGLASHVDIGTALMKSWLNAPSNTLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNE5</accession>
    <name>A0A0N8GNE5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">CDP-paratose 2-epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_08330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062524.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08330"/>
    <dbReference type="EnsemblBacteria" id="KPL77874">
        <property type="protein sequence ID" value="KPL77874"/>
        <property type="gene ID" value="ADN00_08330"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.668"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="6"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="341" mass="37828" checksum="DCB736E01DA8E6B4" modified="2016-01-20" version="1">MSKRTLITGGAGFIGSNYVARLLSRGEDVKVLDNLSRGGAERNLSWLRETYGKDSFELIQADVRDASAVKSAAQDADIIVHLAAQVAVTTSVTDPRTDFEINALGTFNVMEAARASGRAPVVVYASTNKVYGGMEDVEVVEKATRYEYGTLPYGVSEQEPLDFHSPYGCSKGTGDQYVRDYARIYGLPTVVMRQSCIYGPRQFGIEDQGWVAWFIIATVLNRPMTIYGDGKQVRDLLYIDDLLNAYDAAIQRIDITAGQVYNLGGGMVNTISVWKEFGPMLEELAGRDMPVQVGDWRPGDQKVYVSDIRKAKSQLNWSPDVSVQQGVQKLYDWVKQNQNLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNL3</accession>
    <name>A0A0N8GNL3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Isoprenylcysteine carboxyl methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_06750</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000018">
        <property type="protein sequence ID" value="KPL78418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062219.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000018.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06750"/>
    <dbReference type="EnsemblBacteria" id="KPL78418">
        <property type="protein sequence ID" value="KPL78418"/>
        <property type="gene ID" value="ADN00_06750"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007318">
        <property type="entry name" value="Phopholipid_MeTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04191">
        <property type="entry name" value="PEMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="44"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="144"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL78418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="209" mass="24410" checksum="5A7350CC7FB1AA98" modified="2016-01-20" version="1">MITEDIWSHFGSWWAVALWIVLYGVFLLFMPFYKKSQRKPSTAYMAFVVAYALEMFGIPMSMFIIGWAFGITLPEGVLWGHTLGQWIGYWGMYLGIATSLLGGMLIFFGWRRIYKEYWSRNEGTGKIVTGGIYRYIRHPQYTGFMLVTLGMMMEWATLPLLIMWPILGVIYYRLALREEKDMLAEFGEAYAQYRQQTGMFLPRWGKAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNS2</accession>
    <name>A0A0N8GNS2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transport permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_06460</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the ABC-2 integral membrane protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06460"/>
    <dbReference type="EnsemblBacteria" id="KPL78890">
        <property type="protein sequence ID" value="KPL78890"/>
        <property type="gene ID" value="ADN00_06460"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1795"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000412">
        <property type="entry name" value="ABC_2_transport"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51012">
        <property type="entry name" value="ABC_TM2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="41"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="81"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="114"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="151"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="204"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="7">
        <location>
            <begin position="2"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00442"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU361157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL78890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="236" mass="26569" checksum="D84A1C9835ECE9FF" modified="2016-01-20" version="1">MKLRYKGSLLGVIWSLLLPLTQLLVFTFLFRRVIQLDIPNYPIFVFIGVLAWNWFQTSLVAASGSITDNRDLIKRPGFPTLLLPVITVATNLIQFLLALPVLLVFLYLSGGQLTLAFLLLPLILLIQFLFTVSLGYLTATFQVSFRDTQHLLGVVLLLLFYLTPVFYDAGFVPTRFLPIYRLNPMMHIIGAYRNILSKGEPPDFAAIGIVFAASALLLWIGLAVFRRASDTFVEEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNU5</accession>
    <name>A0A0N8GNU5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_04140</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061697.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04140"/>
    <dbReference type="EnsemblBacteria" id="KPL79074">
        <property type="protein sequence ID" value="KPL79074"/>
        <property type="gene ID" value="ADN00_04140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="InterPro"/>
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            <begin position="17"/>
            <end position="42"/>
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            <end position="403"/>
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            <begin position="16"/>
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        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
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    </evidence>
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        <source>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
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    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL79074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="412" mass="44661" checksum="F1576B59F48B8721" modified="2016-01-20" version="1">MTNKTVKTTLKNLPRNVWAVSVTSFLMDISSEMVINVLPLFLSNVLGVKTNLIGLIEGVAEATASLLKMFSGWLSDKLGNRKWLAVLGYVFSALAKPFFYFSSTWGHIAAIRWTDRVGKGIRTAPRDALVADSIREEQRGMAFGFHRAADTAGAVLGLLIALLIVWLGQKSSLTLTASTFQTIVLASLLPAFLAVLALAFGAKEPFVKKKSELPRFAFKSLGKPFMIFMLIMMVFDIGNSSDAFLVLRAQERGLSVTGILGMLVTFNLVYTLVSAPAGSLSDRIGRRTIIIGGWVMYALIYLGFALAQSAAHVWILYTFYGFYYGLSYGTAKAFVADLVPLHLRGTAYGTYNGLLGLLDFPASLIAGILWQGVGSWNGFGAPAPFYFGAAAALLAALLMLLWMPKTAVQSQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNV8</accession>
    <name>A0A0N8GNV8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_04855</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79178">
        <property type="protein sequence ID" value="KPL79178"/>
        <property type="gene ID" value="ADN00_04855"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.338"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="36"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="134" mass="14267" checksum="1C8B2DFC7B6AD8E1" modified="2016-01-20" version="1">MFNRDSKRERTRTVLAIIILATLPCYCLGILMLGSTRSTREPTLTPTLTGTETPLPATGTVTPTLFLSPTPTETVTPTPTFTSSPTPTEFMTPTRTPTATFTATIPPTETTAPPPTETPNLEPSATEQTSESPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNW0</accession>
    <name>A0A0N8GNW0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_04950</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
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            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
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            <taxon>Anaerolineaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79194.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061844.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79194">
        <property type="protein sequence ID" value="KPL79194"/>
        <property type="gene ID" value="ADN00_04950"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="3"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
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        <property type="entry name" value="MEDS_domain"/>
    </dbReference>
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        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
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    </dbReference>
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        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
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    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="3"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
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    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="345"/>
            <end position="391"/>
        </location>
    </feature>
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        <location>
            <begin position="416"/>
            <end position="471"/>
        </location>
    </feature>
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            <end position="542"/>
        </location>
    </feature>
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        <location>
            <begin position="544"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="4">
        <location>
            <begin position="625"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="687"/>
            <end position="714"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL79194.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="760" mass="87205" checksum="8DA871F99938DC1F" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GP67</accession>
    <name>A0A0N8GP67_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01910</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000007">
        <property type="protein sequence ID" value="KPL80050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80050">
        <property type="protein sequence ID" value="KPL80050"/>
        <property type="gene ID" value="ADN00_01910"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="240"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="280"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="329"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="361"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="395"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="420"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="448"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="480"/>
            <end position="501"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="515" mass="57536" checksum="CB9107DC22ED8153" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GPJ2</accession>
    <name>A0A0N8GPJ2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Radical SAM core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_00495</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060994.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00495"/>
    <dbReference type="EnsemblBacteria" id="KPL81050">
        <property type="protein sequence ID" value="KPL81050"/>
        <property type="gene ID" value="ADN00_00495"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3493"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034466">
        <property type="entry name" value="Methyltransferase_Class_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01123">
        <property type="entry name" value="methyltransferase_(Class_B)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Radical SAM core" evidence="2">
        <location>
            <begin position="270"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL81050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="551" mass="63671" checksum="430A6E7DA11EE0DE" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WK98</accession>
    <name>A0A0P6WK98_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_18970</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064612.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70125">
        <property type="protein sequence ID" value="KPL70125"/>
        <property type="gene ID" value="ADN00_18970"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="123" mass="13944" checksum="A80ECC32FCA39522" modified="2016-01-20" version="1">MAKLLGSEYEKLSQLSQNGEFLGVIKIALVKAVREKLTWTVKSGQFQSEEQKTQQQMYAKVTLNDLDNQARRWANVLASWDEYISTVDCEEDLDGSLAFSNFNENGALDYTIRTSLWGVLSNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WM42</accession>
    <name>A0A0P6WM42_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_17935</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000043">
        <property type="protein sequence ID" value="KPL70911.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064414.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000043.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70911">
        <property type="protein sequence ID" value="KPL70911"/>
        <property type="gene ID" value="ADN00_17935"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2169"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="3"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="35"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL70911.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="291" mass="31694" checksum="7D7044909C1D468F" modified="2016-01-20" version="1">MNLHIENLSKQYRAGVWGLKDFNLELGAGVLGLLGPNGAGKSTLMRMLATITRPTRGSISWNGVDVVKSPDALRAVLGYLPQNFGVYPNLSALEFLEYMAAIKGLDGKAARRRIDELLQVVNLTEAARRPLGGYSGGMRQRVGIAQALLNDPQLLIVDEPTVGLDPEERVRFRNLLADLAGERIIVLSTHIVSDVEAIATDIVLINQGQLLDRAAPEDLLRMLDGKVWQWVVPSAELPALKQNFRVSGAIRRVEGVQVRVVSERAPSAEAQAIAPSLEDVYLHRVGMGAHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WQ25</accession>
    <name>A0A0P6WQ25_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH tetR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_17910</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000043">
        <property type="protein sequence ID" value="KPL70908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064411.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000043.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70908">
        <property type="protein sequence ID" value="KPL70908"/>
        <property type="gene ID" value="ADN00_17910"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2164"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041479">
        <property type="entry name" value="TetR_CgmR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17937">
        <property type="entry name" value="TetR_C_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="6"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL70908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="182" mass="20097" checksum="973AD2592E4A9BC1" modified="2016-01-20" version="1">MPKSGENTRTAILDAASRIVQQQGVERLTLDLTAREAGISKGGLLYHFPSKEALIEGMIRYYLEVFTRDLNEAARQQPEDAPGRWTRAYLQTTYEDRQRVPRMSSGLLAAVATNPALLAPMQESFGEWVRLLEDDGIDPTTAAIVRLAVDGLWLVELFGLAAPDADTRARVLAALEAMIRPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WR73</accession>
    <name>A0A0P6WR73_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_16970</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064241.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL71392">
        <property type="protein sequence ID" value="KPL71392"/>
        <property type="gene ID" value="ADN00_16970"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL71392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="339" mass="36950" checksum="63B96376347BE854" modified="2016-01-20" version="1">MNASTQPVELNTAMLEALSRVTPGSRGPLSPLAPHEYSFEVDEPIRQLVDQGFLNLSGEPQDWFLPLLETLLNPTRVIELDASTGQDISLAIFLREDSPVVTLRQLEGQRLQLVAPDQPEECMQILRTLPAPADAAFSANLNLSESRLLGALIDIQRQTALVSAIRGRQQTAEILPVQSRVSSLQRALKDSQANLLSLAWSASACLNSLLSATTESDPSLERDLQNLATTRLISFDRGEYQLDPLVASWANHLLLPQAGLSLTLRQQNLEGKVQIESLISLLSPDTHFTIMARGGGVVSFNPLNPSSLPEISIRLLRGEGSLYDLTGLGNLLTDVAVFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WSZ5</accession>
    <name>A0A0P6WSZ5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Response regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_15260</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063900.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15260"/>
    <dbReference type="EnsemblBacteria" id="KPL72188">
        <property type="protein sequence ID" value="KPL72188"/>
        <property type="gene ID" value="ADN00_15260"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="8"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL72188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="411" mass="45429" checksum="EE23F97D016502F9" modified="2016-01-20" version="1">MPAEEKIRVLIVDDIDETRENVRRLLQFDRDIEVVGSARSGKEAIQLTQQIKPDVVVMDINMPDMDGITATEEILKKMPFVQVVILSVQGDPSYMRRAMLAGARDFLTKPPSIDELTAAIKRAGKMAQEERERSAGTFPSGAAVPGASHGHPVGPLGRIIVVYSPKGGTGVTTIATNLALSLNDPQNEVLLIDASLQFGDVMVFLNEQSKNSVADLSPRAEELDPDIVKDVCFKHSSGISVLAAPPRPEIAEGVEADHFFKMLQYLKQIYRYIIIDTNSYMTEVVQTALELADLIVLVTTQNIPAIKNANLFLSLSDKVGIAREKIIFVMNLFDKHNSISPEKVGETLRQKIHYVIPFDEKVVNLSITRGVPLMVDNKIHPISKTIIMLAEGIRERAAKMDDIGMDLHLKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WT49</accession>
    <name>A0A0P6WT49_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_15810</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063998.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72279">
        <property type="protein sequence ID" value="KPL72279"/>
        <property type="gene ID" value="ADN00_15810"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="164"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="226"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="257"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="281"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="22"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="165"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL72279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="331" mass="36049" checksum="2030F1B5CF4A71DF" modified="2016-01-20" version="1">MNGSQVIAETARKIKERSSRNTGILAALSSALFLGFTPIFGKQALFAGFSPLALVTLRTAIAAGMLFVSMLILHRQFFYIYPVGLIGCALAGLFNGLGSILYYSALNRLDASIAHLIYSFYPIFLAVWQMLDSQPVNRITFIRLGVAIPGVYLLVATGSQNADLPGALLMIGSAILYALHILINQRVLLEVPAPTVTFYTLLSMTVTVTTAFLLFNRQLPPGGTPWWPVLGMAAITFFSRITLFLGVKHLGGMQTTLLGLGELLITVSVAAIWLGERLSPLQWLGALLISCSMLLIGFDRYTPQKRRSTGWLAWLNPPAVNATDLTWPSEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WTM8</accession>
    <name>A0A0P6WTM8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PhageMin_Tail domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_18945</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064608.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18945"/>
    <dbReference type="EnsemblBacteria" id="KPL70120">
        <property type="protein sequence ID" value="KPL70120"/>
        <property type="gene ID" value="ADN00_18945"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3101"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010090">
        <property type="entry name" value="Phage_tape_meas"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10145">
        <property type="entry name" value="PhageMin_Tail"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01760">
        <property type="entry name" value="tape_meas_TP901"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="382"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="420"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="446"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="domain" description="PhageMin_Tail" evidence="2">
        <location>
            <begin position="89"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10145"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL70120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="964" mass="100475" checksum="8F84E8954AA86657" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WV54</accession>
    <name>A0A0P6WV54_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_14155</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063678.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000033.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74139">
        <property type="protein sequence ID" value="KPL74139"/>
        <property type="gene ID" value="ADN00_14155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="184"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="223"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="252"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="280"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="305"/>
            <end position="324"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="356" mass="39234" checksum="4B627BAB9B0A3D05" modified="2016-01-20" version="1">MRLQFSSNKISNQARAAFGFALGLVLMLAVVQVFLVNHFDFDNMRRGTGLLLSGVNPWAPQTRIPHYYNPPFSVLFLWPLLFTTPHLMLVIGGALIFAVIFYQKTWAALAWFATNTFLWLVAAGGVDLYLIGAGLLLLFASDRAPRRWLQTALRVLGYGFLMVKPQGGLFICVFYALKRRDWAGVLVSGLLYGVLFAPLYPHWLRVLISDPPQAQNEASQSLLIQFGPWACAALAGLVLVSRRWKYWQIGGALAGILMPYGMPGIPALLTLSAAGNLAAAPAYVLFSAGLAWLTWTGIPTPQIMGIYHLGMIGLALVLACLLPAPEESDADTIDLRLTTLLKHARRWKNRRGLPTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WVQ4</accession>
    <name>A0A0P6WVQ4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Cupin_5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_18280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064489.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70014">
        <property type="protein sequence ID" value="KPL70014"/>
        <property type="gene ID" value="ADN00_18280"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2962"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06121">
        <property type="entry name" value="cupin_YML079wp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009327">
        <property type="entry name" value="Cupin_DUF985"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039935">
        <property type="entry name" value="YML079W-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33387">
        <property type="entry name" value="PTHR33387"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06172">
        <property type="entry name" value="Cupin_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_5" evidence="1">
        <location>
            <begin position="8"/>
            <end position="146"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="171" mass="19315" checksum="EAB9A29780580433" modified="2016-01-20" version="1">MNAQTIKDILGLEPLPLEGGLYRQSYRSSDILSPACLPSRYPPEAKPISTAIYYLLTNEPDSFSAFHTLPTDEVFHFYLGDPLELHLLYPNGQSQTILLGHNLSEGQHVQYVVPRGVWQGSLVLPGGQYSLIGTTMAPGWSQEDFILASRDELFQRYPHKKEIILRLTRED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WVU5</accession>
    <name>A0A0P6WVU5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_18650</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70069">
        <property type="protein sequence ID" value="KPL70069"/>
        <property type="gene ID" value="ADN00_18650"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="62" mass="7351" checksum="4689B2F13EF8A745" modified="2016-01-20" version="1">MWGKFIRIELLSIVTQEERIGRWFAEPQKKHFGNDRRELVLPSKLVKAVKPQLRGMGYNLLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WYE2</accession>
    <name>A0A0P6WYE2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CheR-type methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_17300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17300"/>
    <dbReference type="EnsemblBacteria" id="KPL71492">
        <property type="protein sequence ID" value="KPL71492"/>
        <property type="gene ID" value="ADN00_17300"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.523"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022642">
        <property type="entry name" value="CheR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000780">
        <property type="entry name" value="CheR_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022641">
        <property type="entry name" value="CheR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01739">
        <property type="entry name" value="CheR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03705">
        <property type="entry name" value="CheR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00996">
        <property type="entry name" value="CHERMTFRASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00138">
        <property type="entry name" value="MeTrc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50123">
        <property type="entry name" value="CHER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CheR-type methyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL71492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="264" mass="30771" checksum="E8DDE7B592048354" modified="2016-01-20" version="1">MQVYSSIKVSVKKLLNIDLEHYKDEQMRRRLDSWLIRTGMKDWESYFGLVSTNPNELLRFRNYLTINVSEFFRDNNRWDALQRSVMPRLLADAQAKRPSKPLKLWSAGCSIGAEPYSLAMMLQEIAPTQEYSILATDLDRGAIENAKNRGPYLDNIVQNMPAFYREKYMEPGGPPYFVKPKVGTRIQFKEHNMLTENFDQNFDLIICRNVIIYFTNEAKSLLYKKFQQALRPGGILFLGGTEIIPRPQEIGFKNLEVSFYIKTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZ32</accession>
    <name>A0A0P6WZ32_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Redox-sensing transcriptional repressor Rex</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rex</name>
        <name evidence="8" type="ORF">ADN00_16060</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Modulates transcription in response to changes in cellular NADH/NAD(+) redox state.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the transcriptional regulatory Rex family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064057.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16060"/>
    <dbReference type="EnsemblBacteria" id="KPL72007">
        <property type="protein sequence ID" value="KPL72007"/>
        <property type="gene ID" value="ADN00_16060"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3647"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051775">
        <property type="term" value="P:response to redox state"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01131">
        <property type="entry name" value="Rex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003781">
        <property type="entry name" value="CoA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009718">
        <property type="entry name" value="Rex_DNA-bd_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022876">
        <property type="entry name" value="Tscrpt_rep_Rex"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35786">
        <property type="entry name" value="PTHR35786"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02629">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06971">
        <property type="entry name" value="Put_DNA-bind_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00881">
        <property type="entry name" value="CoA_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0520">NAD</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0678">Repressor</keyword>
    <keyword evidence="5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="3 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="CoA_binding" evidence="7">
        <location>
            <begin position="80"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="6">
        <location>
            <begin position="16"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="90"/>
            <end position="95"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL72007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="228" mass="24865" checksum="C702855A33F904F9" modified="2016-01-20" version="1">MNNMGIPIPSLRRLLAYYRHLKSASQKGLEFLSSGDLALAAGTTPEQVRKDFSFLPSQGRSRVGYPTQKFAEIIEDYLGLMNDKEAVLVGAGNLGRALALYPGFEQVGLRIVVLFDNDPEKIGNKVGDLQVLPVDALPSLVERMLIRIGIITTTADAAQAVADAMVAGGIKAIWNFSTLRPKVPDDVMVRNMDLSSELIVLSHYIRSLGAQEPPKSLDDDLDRLEQAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZ63</accession>
    <name>A0A0P6WZ63_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_16030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72004">
        <property type="protein sequence ID" value="KPL72004"/>
        <property type="gene ID" value="ADN00_16030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="89" mass="10178" checksum="422495712F81F1E1" modified="2016-01-20" version="1">MKNFNHSSRLAKLWVPNTHKTIGYTYTRYTKYLIPNQDPLTIGATLSGSTVKFPFKGVMTNIQYFNKEINMDDIGKMENYGICVPAIEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZB7</accession>
    <name>A0A0P6WZB7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">NADH oxidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_16630</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064164.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16630"/>
    <dbReference type="EnsemblBacteria" id="KPL72095">
        <property type="protein sequence ID" value="KPL72095"/>
        <property type="gene ID" value="ADN00_16630"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3769"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016156">
        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="SSF55424"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyr_redox_2" evidence="3">
        <location>
            <begin position="3"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="Pyr_redox_dim" evidence="2">
        <location>
            <begin position="333"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL72095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="444" mass="48382" checksum="E4DCA35308074316" modified="2016-01-20" version="1">MSKIVVVGANHAGTAAIKTILSNHPGHQVSVYDSNSNISFLGCGMALWIGAQIDGPEGLFYSSKEQLESMGAVIHMESKVEDINFEQKKIFARAKDGSALEENYDKLILATGSWPIVPNIPGKDLENVQLVKLYQHAGDVIEKIKSPDIKNVVVVGAGYIGVELAEAFQRHGKNTTLIDIEKTCLPVYYDDEFTSLMNQNLQDHGIHLAFGERVVEIRGSGKVEEVVTDKGAYPADMVVLCIGFRPNTNLGGEKVERFKNGAYLVNKKQETSVKDVFAIGDCATVYDNSVNAPNYIALATNAVRSGIVAAHNACGTEIESVGVQGSNGINIYDLKMVSTGLTLKKARSLGINALATDFEDLQKPEFMKSENPPVKIRIVYDADSRVILGAQMASTYDISMGIHLFSLAIQEKVTIEKLALTDIFFLPHFNKPYNYITMAAISAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZN1</accession>
    <name>A0A0P6WZN1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Exonuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_15615</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15615"/>
    <dbReference type="EnsemblBacteria" id="KPL72300">
        <property type="protein sequence ID" value="KPL72300"/>
        <property type="gene ID" value="ADN00_15615"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013520">
        <property type="entry name" value="Exonuclease_RNaseT/DNA_pol3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012337">
        <property type="entry name" value="RNaseH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036397">
        <property type="entry name" value="RNaseH_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00929">
        <property type="entry name" value="RNase_T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00479">
        <property type="entry name" value="EXOIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53098">
        <property type="entry name" value="SSF53098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Exonuclease" evidence="1">
        <location>
            <begin position="10"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="183" mass="20517" checksum="7DF5EEC6B16608A4" modified="2016-01-20" version="1">MAKDLVSCSNAVFFDTETTGFGMDAEIVEITALDNEGKTMLDTLVKPLKPIPPEVSQITHITNEMVAFAPSLQSLKNALEFTFSRKVWVAYNASFDVRMFYQSHQISGIRFAPNFFAVYDAMLIVSNILQMPNPYGGFKWVKLGEAAKLLQVDLGDADLHRAKADTTLMLQILYKISKLERVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X2T3</accession>
    <name>A0A0P6X2T3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ABC transmembrane type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_10720</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062992.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77028">
        <property type="protein sequence ID" value="KPL77028"/>
        <property type="gene ID" value="ADN00_10720"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2619"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="72"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="108"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="142"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="185"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="243"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="73"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL77028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="279" mass="31124" checksum="0FF699F3570383CA" modified="2016-01-20" version="1">MNAKTEKKLKIALSVGLLLLGLACVALPFWYMFVTSLKPQSYVFEFPPRLWPTTPSLDNYVEAVNRDSFGVYFLNSLVVATATTASTVLVSAMLAYAFARFKFPGRNVLFYLLLLGMMIPPVMLIIPQFLVATSLGLREKLIGLVVVYVTMNLSMQTFLLRGFFANIPRDLEEAALIDGASPWQIFTRIILPLSKPGLATVTIFTFLYSWDEFPWANVAIKEATKRTLPIAIALFQSQHLTRWGLVFAASIIALTPVVIVFLVFQKYFVQGISTTGMKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X2W0</accession>
    <name>A0A0P6X2W0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CRISPR system single-strand-specific deoxyribonuclease Cas10/Csm1 (subtype III-A)</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Cyclic oligoadenylate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">ADN00_14280</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CRISPR-associated Cas10/Csm1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000034">
        <property type="protein sequence ID" value="KPL73735.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063706.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000034.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14280"/>
    <dbReference type="EnsemblBacteria" id="KPL73735">
        <property type="protein sequence ID" value="KPL73735"/>
        <property type="gene ID" value="ADN00_14280"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1376"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004527">
        <property type="term" value="F:exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd09680">
        <property type="entry name" value="Cas10_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013408">
        <property type="entry name" value="Cas10/Csm1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041062">
        <property type="entry name" value="Csm1_B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18211">
        <property type="entry name" value="Csm1_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02578">
        <property type="entry name" value="cas_TM1811_Csm1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="7" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0540">Nuclease</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GGDEF" evidence="11">
        <location>
            <begin position="559"/>
            <end position="702"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00014333"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KPL73735.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="820" mass="92072" checksum="47C469418DE6DCB9" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X3U0</accession>
    <name>A0A0P6X3U0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_08610</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000022">
        <property type="protein sequence ID" value="KPL77649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062588.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000022.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77649">
        <property type="protein sequence ID" value="KPL77649"/>
        <property type="gene ID" value="ADN00_08610"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL77649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="280" mass="30178" checksum="E93417D6E77D9AFF" modified="2016-01-20" version="1">MLKIFSTSAQGRSPAKIRAILGLIVVIWLAACAPQPLPLEEVLPSATPSPQPTATIVWFPPTDTPTQLPTRAITPTPDRMVALGDMLVQDGFAQQKSWTTLSSADGNIAFGNQELSLAVASPRITLKSLRAGDIYSDFYMELTAQVNLCRGEDAYGVLARAASEYNAYRLWVRCDGQLRLERLRNGEVALLKDWTPSGQVRPGAPVTNRIGILASGDVLRVFVDGVFQFETRDPVWQSGTFGVLARSSGETSVSVSFRDLSVYSLEGAAIPAAALTPTPN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X3U1</accession>
    <name>A0A0P6X3U1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Deoxynucleoside kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_11590</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063179.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11590"/>
    <dbReference type="EnsemblBacteria" id="KPL76000">
        <property type="protein sequence ID" value="KPL76000"/>
        <property type="gene ID" value="ADN00_11590"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3793"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019136">
        <property type="term" value="F:deoxynucleoside kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01673">
        <property type="entry name" value="dNK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002624">
        <property type="entry name" value="DCK/DGK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031314">
        <property type="entry name" value="DNK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01712">
        <property type="entry name" value="dNK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000705">
        <property type="entry name" value="DNK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="dNK" evidence="4">
        <location>
            <begin position="6"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="81"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="10"/>
            <end position="18"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="46"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="139"/>
            <end position="143"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="148"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="183"/>
            <end position="185"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000705-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000705-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000705-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL76000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="216" mass="25175" checksum="AF634977C1702CFA" modified="2016-01-20" version="1">MAKKLILVAGNIGSGKTSLTERIGERLGWRTAYESVADNPYLSHFYADMRQWSFHLQVFFLGHRAKQHLELWQDPRSAIIDRSIYEDAYIFARALHHMGNLNEIDYQSYRSVFDLVVRSLPAPSLLVYLKAPVPILMERIHRRARNMETGISQDYLSLLESYYDDWLTNFDLCPVLTIRTDDLDFVNQPKHLDIVVERIQEKLSGKEEIIFPKTAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X583</accession>
    <name>A0A0P6X583_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Formate--tetrahydrofolate ligase</fullName>
            <ecNumber evidence="6">6.3.4.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Formyltetrahydrofolate synthetase</fullName>
            <shortName evidence="6">FHS</shortName>
            <shortName evidence="6">FTHFS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">fhs</name>
        <name evidence="7" type="ORF">ADN00_18585</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>(6S)-5,6,7,8-tetrahydrofolate + ATP + formate = (6S)-10-formyltetrahydrofolate + ADP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20221"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 6">One-carbon metabolism; tetrahydrofolate interconversion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the formate--tetrahydrofolate ligase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.3" evidence="6"/>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18585"/>
    <dbReference type="EnsemblBacteria" id="KPL70059">
        <property type="protein sequence ID" value="KPL70059"/>
        <property type="gene ID" value="ADN00_18585"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3026"/>
    <dbReference type="UniPathway" id="UPA00193"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004329">
        <property type="term" value="F:formate-tetrahydrofolate ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00477">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01543">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000559">
        <property type="entry name" value="Formate_THF_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020628">
        <property type="entry name" value="Formate_THF_ligase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01268">
        <property type="entry name" value="FTHFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00721">
        <property type="entry name" value="FTHFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00722">
        <property type="entry name" value="FTHFS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 6 7" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 6" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="88"/>
            <end position="95"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL70059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="642" mass="69533" checksum="C00A14A4C7334468" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="35" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5A0</accession>
    <name>A0A0P6X5A0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 8">DNA-directed RNA polymerase subunit beta</fullName>
            <shortName evidence="6">RNAP subunit beta</shortName>
            <ecNumber evidence="6 8">2.7.7.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">RNA polymerase subunit beta</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Transcriptase subunit beta</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rpoB</name>
        <name evidence="15" type="ORF">ADN00_06880</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 8">DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6 8">
            <text>a ribonucleoside 5'-triphosphate + RNA(n) = diphosphate + RNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:21248"/>
            <dbReference type="Rhea" id="RHEA-COMP:14527"/>
            <dbReference type="Rhea" id="RHEA-COMP:17342"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:140395"/>
            <dbReference type="EC" id="2.7.7.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="6 8">The RNAP catalytic core consists of 2 alpha, 1 beta, 1 beta' and 1 omega subunit. When a sigma factor is associated with the core the holoenzyme is formed, which can initiate transcription.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the RNA polymerase beta chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.6" evidence="6 8"/>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062246.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06880"/>
    <dbReference type="EnsemblBacteria" id="KPL78207">
        <property type="protein sequence ID" value="KPL78207"/>
        <property type="gene ID" value="ADN00_06880"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3192"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003899">
        <property type="term" value="F:DNA-directed 5'-3' RNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032549">
        <property type="term" value="F:ribonucleoside binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00653">
        <property type="entry name" value="RNA_pol_B_RPB2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.270.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01321">
        <property type="entry name" value="RNApol_bact_RpoB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042107">
        <property type="entry name" value="DNA-dir_RNA_pol_bsu_ext_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019462">
        <property type="entry name" value="DNA-dir_RNA_pol_bsu_external_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015712">
        <property type="entry name" value="DNA-dir_RNA_pol_su2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007120">
        <property type="entry name" value="DNA-dir_RNAP_su2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037033">
        <property type="entry name" value="DNA-dir_RNAP_su2_hyb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010243">
        <property type="entry name" value="RNA_pol_bsu_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007121">
        <property type="entry name" value="RNA_pol_bsu_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007644">
        <property type="entry name" value="RNA_pol_bsu_protrusion"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007642">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037034">
        <property type="entry name" value="RNA_pol_Rpb2_2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007645">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007641">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014724">
        <property type="entry name" value="RNA_pol_RPB2_OB-fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20856">
        <property type="entry name" value="PTHR20856"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04563">
        <property type="entry name" value="RNA_pol_Rpb2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04561">
        <property type="entry name" value="RNA_pol_Rpb2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04565">
        <property type="entry name" value="RNA_pol_Rpb2_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10385">
        <property type="entry name" value="RNA_pol_Rpb2_45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00562">
        <property type="entry name" value="RNA_pol_Rpb2_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04560">
        <property type="entry name" value="RNA_pol_Rpb2_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01166">
        <property type="entry name" value="RNA_POL_BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6 8" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="3 6 8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6 8" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="RNA_pol_Rpb2_1" evidence="12">
        <location>
            <begin position="22"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb2_2" evidence="11">
        <location>
            <begin position="142"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb2_3" evidence="13">
        <location>
            <begin position="413"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb2_45" evidence="14">
        <location>
            <begin position="556"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb2_6" evidence="9">
        <location>
            <begin position="675"/>
            <end position="1198"/>
        </location>
    </feature>
    <feature type="domain" description="RNA_pol_Rpb2_7" evidence="10">
        <location>
            <begin position="1200"/>
            <end position="1274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00024550"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF04561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF04563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF04565"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF10385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KPL78207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="1310" mass="147528" checksum="2901E9F58258CE7F" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5E3</accession>
    <name>A0A0P6X5E3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Probable inosine/xanthosine triphosphatase</fullName>
            <shortName evidence="3">ITPase/XTPase</shortName>
            <ecNumber evidence="3">3.6.1.73</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Non-canonical purine NTP phosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Non-standard purine NTP phosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Nucleoside-triphosphate phosphatase</fullName>
            <shortName evidence="3">NTPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_07335</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Phosphatase that hydrolyzes non-canonical purine nucleotides such as XTP and ITP to their respective diphosphate derivatives. Probably excludes non-canonical purines from DNA/RNA precursor pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>H2O + ITP = H(+) + IDP + phosphate</text>
            <dbReference type="Rhea" id="RHEA:28330"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58280"/>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
            <dbReference type="EC" id="3.6.1.73"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>H2O + XTP = H(+) + phosphate + XDP</text>
            <dbReference type="Rhea" id="RHEA:28406"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:59884"/>
            <dbReference type="ChEBI" id="CHEBI:61314"/>
            <dbReference type="EC" id="3.6.1.73"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="3">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="3">Binds 1 divalent metal cation per subunit; can use either Mg(2+) or Mn(2+).</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the YjjX NTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.73" evidence="3"/>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062330.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07335"/>
    <dbReference type="EnsemblBacteria" id="KPL78271">
        <property type="protein sequence ID" value="KPL78271"/>
        <property type="gene ID" value="ADN00_07335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103023">
        <property type="term" value="F:ITPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017111">
        <property type="term" value="F:nucleoside-triphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00648">
        <property type="entry name" value="Non_canon_purine_NTPase_YjjX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002786">
        <property type="entry name" value="Non_canon_purine_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026533">
        <property type="entry name" value="NTPase/PRRC1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01931">
        <property type="entry name" value="NTPase_I-T"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52972">
        <property type="entry name" value="SSF52972"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00258">
        <property type="entry name" value="TIGR00258"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 3" id="KW-0464">Manganese</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NTPase_I-T" evidence="4">
        <location>
            <begin position="7"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL78271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="177" mass="19696" checksum="AE3AA4CC6BFB7046" modified="2016-01-20" version="1">MKKIVMASANPVKAKAVLQGFQRMFTEETFEIQTLEVPSGVSDQPMTDEETLQGALNRSQRARELISNADYWVGIEGGVYEHENDLHAFAWVVVRSPDGIGKSRSGSFELPSVIRDLVHSGVELGKADDMVFQRYNSKQSNGAIGILTQDVIDRTALYEHAVILALVPFRNRELFGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5W9</accession>
    <name>A0A0P6X5W9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sugar ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_09450</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062743.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77335">
        <property type="protein sequence ID" value="KPL77335"/>
        <property type="gene ID" value="ADN00_09450"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="85"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="114"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="150"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="189"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="245"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="79"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL77335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="284" mass="32064" checksum="1C1D04E40A86443F" modified="2016-01-20" version="1">MNLFRYLRKHFNIGEMLKWILAVNFMVMALFPIWWMFNIVFSEPGIPIAINPRLYPSSFTAGIENIKQVLSEANVLAAYAHSLEYSFLTMLGSLLLTSMAAFEFALFDFPGKKILFGIVLVALMIPTAVTLVPTYLLVANFGWVNKMQGLVVPGLASAFGLFMLTQFFKDIPRELMDAALIDGDNHFGVYWHIVLPLSRNALATMAILTFMTTWGNYVWPMVIAKNNDIITVSQMINWYNDPNSFMTVNLMMTAFFLAALLPIVVYVIFQRQIIQGISITGLKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X6K8</accession>
    <name>A0A0P6X6K8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05430</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78692">
        <property type="protein sequence ID" value="KPL78692"/>
        <property type="gene ID" value="ADN00_05430"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="90" mass="10102" checksum="5849927B97A12F79" modified="2016-01-20" version="1">MITEIEVSRTPGRPPSPVPRRKIGTTLSQGEIHELNKWQKRLSDLLDRKVSTGETVGILARVCSARLARIQDQGNPKTLEDLVQRMIGEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X6S5</accession>
    <name>A0A0P6X6S5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_08590</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000022">
        <property type="protein sequence ID" value="KPL77646.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062584.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000022.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77646">
        <property type="protein sequence ID" value="KPL77646"/>
        <property type="gene ID" value="ADN00_08590"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.400.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045857">
        <property type="entry name" value="O16G_dom_2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL77646.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="543" mass="60133" checksum="2882C077824EA8A1" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X6Z8</accession>
    <name>A0A0P6X6Z8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Tungstate transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_12160</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063287.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12160"/>
    <dbReference type="EnsemblBacteria" id="KPL76091">
        <property type="protein sequence ID" value="KPL76091"/>
        <property type="gene ID" value="ADN00_12160"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3908"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="98"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="154"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="201"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="26"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL76091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="233" mass="25122" checksum="09C29679CE640804" modified="2016-01-20" version="1">MELIWQGVLEAIRLLFSGDAEVFEITLLSLKISGIATGISLLIGLPLGTLLALGQFPSRKFWISLINTGMALPPVVVGLGVSILLWRSGPLGDLRWMYTTQAIIIAQIIIAAPVVTGLTVAALQQLDLRLQFQLLGLGASRWQMVLMLWREARLPLLAALMAGFGSVISEVGASMMVGGNLRYQTRVLTTAIVLETSKGNFALAIALSLLLLALAYAVNLVLTSIQQSRSNRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X881</accession>
    <name>A0A0P6X881_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Histidine kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_11050</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11050"/>
    <dbReference type="EnsemblBacteria" id="KPL76502">
        <property type="protein sequence ID" value="KPL76502"/>
        <property type="gene ID" value="ADN00_11050"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="43"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="74"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="110"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="139"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="172"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="207"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="276"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="306"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="505"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="436"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL76502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="736" mass="80871" checksum="F6B3A744DE7A29D4" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X8D5</accession>
    <name>A0A0P6X8D5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_07565</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07565"/>
    <dbReference type="EnsemblBacteria" id="KPL78359">
        <property type="protein sequence ID" value="KPL78359"/>
        <property type="gene ID" value="ADN00_07565"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3340"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.180.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02469">
        <property type="entry name" value="Fasciclin"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00554">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="SSF82153"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50213">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAS1" evidence="1">
        <location>
            <begin position="23"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="1">
        <location>
            <begin position="156"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="1">
        <location>
            <begin position="288"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="1">
        <location>
            <begin position="420"/>
            <end position="550"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="554" mass="57540" checksum="2EFEBCD38B2AC1C2" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X8F6</accession>
    <name>A0A0P6X8F6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BTAD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_17395</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71457.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064319.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17395"/>
    <dbReference type="EnsemblBacteria" id="KPL71457">
        <property type="protein sequence ID" value="KPL71457"/>
        <property type="gene ID" value="ADN00_17395"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005158">
        <property type="entry name" value="BTAD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03704">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01043">
        <property type="entry name" value="BTAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="620"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="domain" description="BTAD" evidence="2">
        <location>
            <begin position="932"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="989"/>
            <end position="1022"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL71457.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="1074" mass="123273" checksum="DCFC47EDB1ED0E94" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X8H2</accession>
    <name>A0A0P6X8H2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Cobalamin biosynthesis protein CbiM</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_06720</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000018">
        <property type="protein sequence ID" value="KPL78414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06720"/>
    <dbReference type="EnsemblBacteria" id="KPL78414">
        <property type="protein sequence ID" value="KPL78414"/>
        <property type="gene ID" value="ADN00_06720"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000041">
        <property type="term" value="P:transition metal ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002751">
        <property type="entry name" value="CbiM/NikMN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025937">
        <property type="entry name" value="PDGLE_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01891">
        <property type="entry name" value="CbiM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13190">
        <property type="entry name" value="PDGLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="72"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="103"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="137"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="176"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="220"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="278"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="PDGLE" evidence="8">
        <location>
            <begin position="231"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL78414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="312" mass="31780" checksum="D7DEA3679F5200F8" modified="2016-01-20" version="1">MHIPDGFLSVLVSALFWVISVLVIAVALRRVSRDLGEREAPLMGVLAAAIFAGQMLNFSVSGGTSGHLLGAALAAILVGPWAAVLVMTAVVATQALIFQDGGLVVMGANLFNMAVVGVAVGYAVYRLAQKLTGGQRWGILASGFLAAWASIFIASLSCALQLALSGTSPVQVAVPAMAGIHALIGVGEGLITIGALAFVLAARPDLLSAAQTPAKHSRGLLVGGLGIATLLAVLSPLASSHPDGLEWVAEQAGFLEAARGPWFEIIPDYVLPGIQNEALATILAGVIGVMIVLAAVSGVTLARRKQAVSEQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X941</accession>
    <name>A0A0P6X941_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_12285</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76112">
        <property type="protein sequence ID" value="KPL76112"/>
        <property type="gene ID" value="ADN00_12285"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="109" mass="12838" checksum="930CCF0EC0C416F9" modified="2016-01-20" version="1">MPKSQEQEVRKVYIYSRVAELEKFAVKDGAIMAYSGHVNQQADAYIRENFYHWFVMIPGEDITKGFHTEDEFNRYIETIGIQDPDWQTPDDAFDTFLKTGCLDWFPDCK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9U9</accession>
    <name>A0A0P6X9U9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ATP-dependent 6-phosphofructokinase</fullName>
            <shortName evidence="9">ATP-PFK</shortName>
            <shortName evidence="9">Phosphofructokinase</shortName>
            <ecNumber evidence="9">2.7.1.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Phosphohexokinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">pfkA</name>
        <name evidence="11" type="ORF">ADN00_10445</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + beta-D-fructose 6-phosphate = ADP + beta-D-fructose 1,6-bisphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16109"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 9">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer or homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="9">Belongs to the phosphofructokinase type A (PFKA) family. Mixed-substrate PFK group III subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.11" evidence="9"/>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062943.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10445"/>
    <dbReference type="EnsemblBacteria" id="KPL76987">
        <property type="protein sequence ID" value="KPL76987"/>
        <property type="gene ID" value="ADN00_10445"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2560"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00182"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003872">
        <property type="term" value="F:6-phosphofructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047334">
        <property type="term" value="F:diphosphate-fructose-6-phosphate 1-phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006002">
        <property type="term" value="P:fructose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.460">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01976">
        <property type="entry name" value="Phosphofructokinase_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022953">
        <property type="entry name" value="ATP_PFK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012003">
        <property type="entry name" value="ATP_PFK_prok-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000023">
        <property type="entry name" value="Phosphofructokinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012829">
        <property type="entry name" value="Phosphofructokinase_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035966">
        <property type="entry name" value="PKF_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00365">
        <property type="entry name" value="PFK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000532">
        <property type="entry name" value="ATP_PFK_prok"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00476">
        <property type="entry name" value="PHFRCTKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53784">
        <property type="entry name" value="SSF53784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 9" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="6 9 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="7 9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PFK" evidence="10">
        <location>
            <begin position="6"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="134"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="178"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="297"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="9">
        <location>
            <position position="136"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="13"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="75"/>
            <end position="76"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="291"/>
        </location>
        <ligand>
            <name>substrate</name>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="site" description="Important for substrate specificity; cannot use PPi as phosphoryl donor" evidence="9">
        <location>
            <position position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL76987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="373" mass="39443" checksum="7CC32C7E5B83414A" modified="2016-01-20" version="1">MTGKMVGVLTAGGDTPGLNAALRGLGKAALGEYGMHLIGFQDGFRGLMQNRMVRLDEHALSGILTIGGTILGTSRDKPHKMPVGGKLVDMTDEIVAVYQSHHLDYLVCLGGGGTQKSALRLKNKGLNVVTLPKTIDNDVAGTDTTFGFDTALSIATEAIDRLHSTAHSHHRIIVVEIMGHNAGWLALGAGLAGGADVILVPEIPYDVEKIAEAILQRSRGGKRFSIVAVSEGALSVEDAQVKGALLKQLEKGDKADRKKAEEDLAQFELAHVGNTMRLSAKLEELTALESRVTILGYLQRGGAPSAADRLLATKLGTSAACFIHEGKAGVMASVRGEKVIPVPLEEVAGQRKLVPLDHVWLDSARKVGTCFGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9X8</accession>
    <name>A0A0P6X9X8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062974.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77014">
        <property type="protein sequence ID" value="KPL77014"/>
        <property type="gene ID" value="ADN00_10620"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="60" mass="6455" checksum="826FF2D99726247C" modified="2016-01-20" version="1">MNKDESIKKIVTLVLKAVGLAMPVAVIVLNALKVMDIESQVPLLAIGLFCLALAMMQSEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9Z9</accession>
    <name>A0A0P6X9Z9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminotransferase</fullName>
            <ecNumber evidence="1">2.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_06405</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.-" evidence="1"/>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78889.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06405"/>
    <dbReference type="EnsemblBacteria" id="KPL78889">
        <property type="protein sequence ID" value="KPL78889"/>
        <property type="gene ID" value="ADN00_06405"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="2">
        <location>
            <begin position="15"/>
            <end position="356"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78889.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="372" mass="41792" checksum="A307830A95283FD9" modified="2016-01-20" version="1">MLVGADPFFPDPCIPDHIIEATKKALDGGHTHYALDNSYAVPPLKETLVKKLKVFNHLDVDPENELIVVPSSAFGLYAGIRICVRPNMGDEVLNIDPGFAENFNDVVQIGATSVSVPVYPEDGFQIRREELEKAVTPNTRCLVLTHPNNPTSTVYKREVLEDVAAFLEDHDLMVVVDQSFERNIYDNREYITFATLKGMKERTISVFGTSKDLGLTGFRVAYMVAPKQIIDILKIATFNYVGPTNTFAQYGVAAGYQDPSYVDEWMKVFNYRRQYGYNLLKQIPGVKCQLPEGGYFFWVDIRALGTSTEVRDFLIKDANVGVSPGNWFGSHGEGYLRIMFSTMRDTAKYEEAMQRIHQSLMKLAELKGVAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XA03</accession>
    <name>A0A0P6XA03_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_15915</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL71988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064029.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL71988">
        <property type="protein sequence ID" value="KPL71988"/>
        <property type="gene ID" value="ADN00_15915"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL71988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="159" mass="17132" checksum="791EE86F7A67F328" modified="2016-01-20" version="1">MIKKGILIGLLVLVSGFLVLGGINRTLAKTRGITLFHFIPGMAVADEPSQGNGVRLNLSESREGSSSSDWVTLEGLVTSVNELAIQVKMPDGSSIVLEDRAWEYAQLQGFGANAGDTLELTGFYEDDDFETAILSNLSSGEKLWLRNNSGRPMWAGKGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAK9</accession>
    <name>A0A0P6XAK9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Flavodoxin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_08970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77261.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062659.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08970"/>
    <dbReference type="EnsemblBacteria" id="KPL77261">
        <property type="protein sequence ID" value="KPL77261"/>
        <property type="gene ID" value="ADN00_08970"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026816">
        <property type="entry name" value="Flavodoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12724">
        <property type="entry name" value="Flavodoxin_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="1">
        <location>
            <begin position="5"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77261.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="171" mass="19682" checksum="A4F5302B7C919B3A" modified="2016-01-20" version="1">MPDTLLVGYASQSGSTEEVAEFIALNLAEHGYMIDLLSVNYIRKLTGYRLIVLGAPLYYSHLHRDMRRFLKAHQSELTVTPVAFYALGPVHKTDEEYNGAKNQLAKELAKLNWFKPFDVQLFTGMIDPAKLGFPYKLIPRIRELEMTDERNWDQISAWVESLAKKLENDIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBK4</accession>
    <name>A0A0P6XBK4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">3-phosphoshikimate 1-carboxyvinyltransferase</fullName>
            <ecNumber evidence="7">2.5.1.19</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">5-enolpyruvylshikimate-3-phosphate synthase</fullName>
            <shortName evidence="7">EPSP synthase</shortName>
            <shortName evidence="7">EPSPS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">aroA</name>
        <name evidence="9" type="ORF">ADN00_02465</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the transfer of the enolpyruvyl moiety of phosphoenolpyruvate (PEP) to the 5-hydroxyl of shikimate-3-phosphate (S3P) to produce enolpyruvyl shikimate-3-phosphate and inorganic phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>3-phosphoshikimate + phosphoenolpyruvate = 5-O-(1-carboxyvinyl)-3-phosphoshikimate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21256"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57701"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
            <dbReference type="EC" id="2.5.1.19"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 6/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the EPSP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.19" evidence="7"/>
    <dbReference type="EMBL" id="LGCL01000011">
        <property type="protein sequence ID" value="KPL79566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061375.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000011.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02465"/>
    <dbReference type="EnsemblBacteria" id="KPL79566">
        <property type="protein sequence ID" value="KPL79566"/>
        <property type="gene ID" value="ADN00_02465"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2803"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00089"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003866">
        <property type="term" value="F:3-phosphoshikimate 1-carboxyvinyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd01556">
        <property type="entry name" value="EPSP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.65.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00210">
        <property type="entry name" value="EPSP_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001986">
        <property type="entry name" value="Enolpyruvate_Tfrase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036968">
        <property type="entry name" value="Enolpyruvate_Tfrase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006264">
        <property type="entry name" value="EPSP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023193">
        <property type="entry name" value="EPSP_synthase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013792">
        <property type="entry name" value="RNA3'P_cycl/enolpyr_Trfase_a/b"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00275">
        <property type="entry name" value="EPSP_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000505">
        <property type="entry name" value="EPSPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55205">
        <property type="entry name" value="SSF55205"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01356">
        <property type="entry name" value="aroA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00885">
        <property type="entry name" value="EPSP_SYNTHASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="6 7" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="EPSP_synthase" evidence="8">
        <location>
            <begin position="7"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Shikimate-3-phosphate binding" evidence="7">
        <location>
            <begin position="22"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="314"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="342"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>3-phosphoshikimate</name>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="341"/>
        </location>
        <ligand>
            <name>3-phosphoshikimate</name>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="345"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="387"/>
        </location>
        <ligand>
            <name>phosphoenolpyruvate</name>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00210"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00275"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL79566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="429" mass="45117" checksum="E361C1ED6682F311" modified="2016-01-20" version="1">MKSLTIHPSANLQGQCRLPGDKSISHRALLFNAIAEGEARITNFLPGEDCQATLGCLRDLGVRVEQEDATTLIVHGVGLRGLRAPAAPLNCIRSGTTMRLLMGLLAGQAFDTTLTGDEQLLRRPMERVAAPLRQLGARMETTNGRAPLWIQGGPLNGGQVEIAVASAQIKSALLLAGLYAQSAVTVVEPGPSRDHSERMLSAMGASVEKNGLRVTIQPAARLNALSIQIPGDVSSAAFLIAAAVLAPHSQVKLLDVGVNPTRTGLPDMLRNMGAQISIEDAHMQGGEAVANIHVQTSQLKAVTVSGETVVRMIDEFPIFAVLATQAKGATIVRDAAELRVKETDRIATTAEELNRLGADVTPTPDGFIIKGPTPLRGGEADSHGDHRLAMALAVAGLITSEPLTVTNTHCIGDSFPGFEGLLRGLGARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBU1</accession>
    <name>A0A0P6XBU1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_15585</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72238.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063954.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72238">
        <property type="protein sequence ID" value="KPL72238"/>
        <property type="gene ID" value="ADN00_15585"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72238.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="235" mass="27213" checksum="0F8EA1B6A8D37132" modified="2016-01-20" version="1">MSDDALRVLVDLRDLTIQKIRIGFGNRIMAIEGGRDQADEATIDILDRYNYLFSELEDELNKDISKLVAKYPIINKMMEVRGIGPTLAAKLVSLIDIRKADSVSALWRYCGYGVQDGKRERLVKGERAHFNQRAKTACYLIGSSFLKSRSPYRRVYDDARQYYEANRKDWTKAHIHNAALRKMVKVFLAHLWNEWRILEGLPTKPLYVNEKLGHTTEFLPEEFGWKTDEAVLETV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDV2</accession>
    <name>A0A0P6XDV2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">Glutamine--fructose-6-phosphate aminotransferase [isomerizing]</fullName>
            <ecNumber evidence="2 8">2.6.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">D-fructose-6-phosphate amidotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">GFAT</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Glucosamine-6-phosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Hexosephosphate aminotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">L-glutamine--D-fructose-6-phosphate amidotransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">glmS</name>
        <name evidence="11" type="ORF">ADN00_00830</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>D-fructose 6-phosphate + L-glutamine = D-glucosamine 6-phosphate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:13237"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:58725"/>
            <dbReference type="ChEBI" id="CHEBI:61527"/>
            <dbReference type="EC" id="2.6.1.16"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.16" evidence="2 8"/>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061052.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00830"/>
    <dbReference type="EnsemblBacteria" id="KPL81102">
        <property type="protein sequence ID" value="KPL81102"/>
        <property type="gene ID" value="ADN00_00830"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3564"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004360">
        <property type="term" value="F:glutamine-fructose-6-phosphate transaminase (isomerizing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901137">
        <property type="term" value="P:carbohydrate derivative biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd05008">
        <property type="entry name" value="SIS_GlmS_GlmD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05009">
        <property type="entry name" value="SIS_GlmS_GlmD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00164">
        <property type="entry name" value="GlmS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017932">
        <property type="entry name" value="GATase_2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035466">
        <property type="entry name" value="GlmS/AgaS_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035490">
        <property type="entry name" value="GlmS/FrlB_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005855">
        <property type="entry name" value="GlmS_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10937:SF0">
        <property type="entry name" value="PTHR10937:SF0"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01380">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01135">
        <property type="entry name" value="glmS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51278">
        <property type="entry name" value="GATASE_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 8" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 11" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 8 11" id="KW-0808">Transferase</keyword>
    <feature type="initiator methionine" description="Removed" evidence="8">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <feature type="domain" description="Glutamine amidotransferase type-2" evidence="9">
        <location>
            <begin position="2"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="10">
        <location>
            <begin position="290"/>
            <end position="429"/>
        </location>
    </feature>
    <feature type="domain" description="SIS" evidence="10">
        <location>
            <begin position="462"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; for GATase activity" evidence="8">
        <location>
            <position position="2"/>
        </location>
    </feature>
    <feature type="active site" description="For Fru-6P isomerization activity" evidence="8">
        <location>
            <position position="608"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012916"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00016090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL81102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="613" mass="67120" checksum="65A66C2AB6E88806" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XE22</accession>
    <name>A0A0P6XE22_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Ald_Xan_dh_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_14960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000036">
        <property type="protein sequence ID" value="KPL73107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14960"/>
    <dbReference type="EnsemblBacteria" id="KPL73107">
        <property type="protein sequence ID" value="KPL73107"/>
        <property type="gene ID" value="ADN00_14960"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1855"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000674">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036856">
        <property type="entry name" value="Ald_Oxase/Xan_DH_a/b_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016208">
        <property type="entry name" value="Ald_Oxase/xanthine_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008274">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037165">
        <property type="entry name" value="AldOxase/xan_DH_Mopterin-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11908">
        <property type="entry name" value="PTHR11908"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01315">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02738">
        <property type="entry name" value="Ald_Xan_dh_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01008">
        <property type="entry name" value="Ald_Xan_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54665">
        <property type="entry name" value="SSF54665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56003">
        <property type="entry name" value="SSF56003"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ald_Xan_dh_C" evidence="1">
        <location>
            <begin position="21"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL73107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="766" mass="84320" checksum="E8B46477B6C054F5" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XEQ0</accession>
    <name>A0A0P6XEQ0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PTS EIIB type-2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_05225</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78660.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061919.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05225"/>
    <dbReference type="EnsemblBacteria" id="KPL78660">
        <property type="protein sequence ID" value="KPL78660"/>
        <property type="gene ID" value="ADN00_05225"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022877">
        <property type="term" value="F:protein-N(PI)-phosphohistidine-fructose phosphotransferase system transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05569">
        <property type="entry name" value="PTS_IIB_fructose"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036095">
        <property type="entry name" value="PTS_EIIB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013011">
        <property type="entry name" value="PTS_EIIB_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003501">
        <property type="entry name" value="PTS_EIIB_2/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003353">
        <property type="entry name" value="PTS_IIB_fruc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02302">
        <property type="entry name" value="PTS_IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52794">
        <property type="entry name" value="SSF52794"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00829">
        <property type="entry name" value="FRU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51099">
        <property type="entry name" value="PTS_EIIB_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PTS EIIB type-2" evidence="2">
        <location>
            <begin position="1"/>
            <end position="99"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78660.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="108" mass="11472" checksum="E2E5C21E425AA88B" modified="2016-01-20" version="1">MKIVAVTACAGGIAHSYMAAEAIKKSAKKAGDEAKVEIQGSMGLENRLKQSEIDEADMVLLVANIAVREIGRFKGKKIVEIDPGKFVADGDKSLLLAKEKGGFIPTNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XF17</accession>
    <name>A0A0P6XF17_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">ADN00_06045</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the organic radical-activating enzymes family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062069.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06045"/>
    <dbReference type="EnsemblBacteria" id="KPL78788">
        <property type="protein sequence ID" value="KPL78788"/>
        <property type="gene ID" value="ADN00_06045"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1688"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040074">
        <property type="entry name" value="BssD/PflA/YjjW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034457">
        <property type="entry name" value="Organic_radical-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012839">
        <property type="entry name" value="Organic_radical_activase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001989">
        <property type="entry name" value="Radical_activat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30352">
        <property type="entry name" value="PTHR30352"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000371">
        <property type="entry name" value="PFL_act_enz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01118">
        <property type="entry name" value="activating_enzymes__group_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01087">
        <property type="entry name" value="RADICAL_ACTIVATING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="10">
        <location>
            <begin position="14"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="9">
        <location>
            <begin position="45"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="9">
        <location>
            <begin position="75"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL78788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="302" mass="34168" checksum="166306DD5396995E" modified="2016-01-20" version="1">MTGVVFSIERYALQDGPGIRTLVFLKGCPLNCQWCANPESQSCAPEILYFQNRCASCGRCIANCPQGAIKVDDEFGLITDPDRCMLCGLCVDACYYGARELSGEEMEVCDVMNIIERDKMFYDATQGGVTLSGGEPLLQTAFVRELTRECKERGIHTAIETTLFADKEIVKRALEYIDLVFVDVKHFDPYKHAEFTGVRNELIINNIEMIDNLGKQFIIRIPFIPGVNDDDETQKQIYQWASRLRNLKWIEVLPYHRLGMTKYRGLGRMYPLADVKPVSKQSLTYLKDLGAQIGVDVRIGAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XFA9</accession>
    <name>A0A0P6XFA9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Aspartate carbamoyltransferase</fullName>
            <ecNumber evidence="5">2.1.3.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Aspartate transcarbamylase</fullName>
            <shortName evidence="5">ATCase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">pyrB</name>
        <name evidence="9" type="ORF">ADN00_06335</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>carbamoyl phosphate + L-aspartate = H(+) + N-carbamoyl-L-aspartate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20013"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:32814"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="EC" id="2.1.3.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; (S)-dihydroorotate from bicarbonate: step 2/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.2" evidence="5"/>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062180.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06335"/>
    <dbReference type="EnsemblBacteria" id="KPL78888">
        <property type="protein sequence ID" value="KPL78888"/>
        <property type="gene ID" value="ADN00_06335"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1769"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00116"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016597">
        <property type="term" value="F:amino acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004070">
        <property type="term" value="F:aspartate carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1370">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00001">
        <property type="entry name" value="Asp_carb_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006132">
        <property type="entry name" value="Asp/Orn_carbamoyltranf_P-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006130">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036901">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002082">
        <property type="entry name" value="Asp_carbamoyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006131">
        <property type="entry name" value="Asp_carbamoyltransf_Asp/Orn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11405:SF16">
        <property type="entry name" value="PTHR11405:SF16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00185">
        <property type="entry name" value="OTCace"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02729">
        <property type="entry name" value="OTCace_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00100">
        <property type="entry name" value="AOTCASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53671">
        <property type="entry name" value="SSF53671"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00670">
        <property type="entry name" value="asp_carb_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00097">
        <property type="entry name" value="CARBAMOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="OTCace_N" evidence="8">
        <location>
            <begin position="14"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="OTCace" evidence="7">
        <location>
            <begin position="164"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00001"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL78888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="317" mass="35426" checksum="54F4FE75B8670B63" modified="2016-01-20" version="1">MSRKPGFQNGFFKKDILSVDQFDRDGLAYIFTRTDEMSEMVETVGACDLLHGYTLACVFYEPSTRTSASFIAAMERLGGNVIPITQGIQYSSVSKGESLVDTIITLEQYSDVIVLRHPEIGSVAKTAKYSGVPVINAGDGAGEHPTQALLDLYTIRKELGSLNGLRVAMVGDLRNGRTVHSLTKLLMNYDISLRLVSPDVLRLPLGMMNELIDKGIDVRETDRVEDVIKDVDVLYVTRIQKERFTDMAQYEEVKNYFEITPEVMANAKDKMVVMHPLPRVGEIHYTVDKDPRAAYFRQVKNGMYVRMALLAAVLGQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XFZ3</accession>
    <name>A0A0P6XFZ3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">bPH_1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_14140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063675.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000033.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74136">
        <property type="protein sequence ID" value="KPL74136"/>
        <property type="gene ID" value="ADN00_14140"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1929"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012544">
        <property type="entry name" value="PHb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037063">
        <property type="entry name" value="PHb_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08000">
        <property type="entry name" value="bPH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="bPH_1" evidence="1">
        <location>
            <begin position="2"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="123" mass="13875" checksum="4ED4CCFDFD9BD385" modified="2016-01-20" version="1">MLQALFGNASEVDSKNLQRDLNAILCEGEQVVKAFRVLRDLFIFTDKRLVLVDKQGLTGSKVEYHSIPYRAISHFAVESPGTFDLDSEVKIYLIGEPNPIVREFKRGTDITGFQKALAQFVLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGS6</accession>
    <name>A0A0P6XGS6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_03085</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000014">
        <property type="protein sequence ID" value="KPL79327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061495.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000014.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79327">
        <property type="protein sequence ID" value="KPL79327"/>
        <property type="gene ID" value="ADN00_03085"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="3"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL79327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="257" mass="28236" checksum="56782C1DA9E30A07" modified="2016-01-20" version="1">MRLQVMSVSHEFRNGSVRPALEGVSLTVEEGQFVALVGPSGCGKSTLLRLCANLLQPTRGQITLDGQPPAHAVTQRQIAWLAQSPALLPWLTALQNVELAGRFHNVQRETRLSPREALEMVGLADAAGVYPHALSGGMQQRLALARLLTQEAALWLMDEPFAALDELTRERLTLELAEIWGRLRPTVVWVTHNIHEALRLADRVVVFSPAPGRLRADVAVDLPRPRVESDAAYQALLRQLRAALQGLPAADELLEAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGY6</accession>
    <name>A0A0P6XGY6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fuculose phosphate aldolase</fullName>
            <ecNumber evidence="2">4.1.2.17</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_03255</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.2.17" evidence="2"/>
    <dbReference type="EMBL" id="LGCL01000014">
        <property type="protein sequence ID" value="KPL79355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061524.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000014.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03255"/>
    <dbReference type="EnsemblBacteria" id="KPL79355">
        <property type="protein sequence ID" value="KPL79355"/>
        <property type="gene ID" value="ADN00_03255"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2062"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008738">
        <property type="term" value="F:L-fuculose-phosphate aldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.225.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001303">
        <property type="entry name" value="Aldolase_II/adducin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036409">
        <property type="entry name" value="Aldolase_II/adducin_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00596">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01007">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53639">
        <property type="entry name" value="SSF53639"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldolase_II" evidence="1">
        <location>
            <begin position="8"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="216" mass="24076" checksum="89220A80FD93876D" modified="2016-01-20" version="1">MRLQNEREQLVAYGKRLITSHLTTGSGGNLSILNREEGLVAITPSGMDYFTTQPEDIVVLDLDGNIVEGKRKPSSEWRFHLDLLQHRDNINAVVHTHQVYATTFACLNWEIPAVHYLVGFSGDKVPVAPYATYGTQELSDNILKTIGDYNVVLLANHGLIAVGHSMERAFAAAEEIELVAQLYYQTKCIGQPVILNNEQMGEVLMSFQGYGQGRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XH17</accession>
    <name>A0A0P6XH17_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_04230</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061712.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04230"/>
    <dbReference type="EnsemblBacteria" id="KPL79084">
        <property type="protein sequence ID" value="KPL79084"/>
        <property type="gene ID" value="ADN00_04230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="295" mass="33530" checksum="5F4E3FA4F70BBBA7" modified="2016-01-20" version="1">MQHLKDIFAGYPCLALTNGLLTLHVMQNAGPRIIGLQAAEGPNLMAEVPLAGEQPNEFIPRGGQRLWHAPEDLRRTYIADNEPVSFAFNAESVLVTQNIEKETGIQKSMEISMPTGRAEVRVKYGLQNHNLWPVTFAAWPIAQMRMGGFAILPQSARATGLLPNRRLVIWPYTDIQSENIVLGNRYIFVQARYQGEQKAKIGWLNDRGWMGYYLDNTLIIKQARFEPQGQYVDMGCNMECYCDRRFLEMETLSPLTSVQPGGTLEYEEKWLVFSNLNVSMSEESIEEVIRDLNIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XHJ2</accession>
    <name>A0A0P6XHJ2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Fatty acid hydroxylase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">ADN00_02525</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Endoplasmic reticulum membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000011">
        <property type="protein sequence ID" value="KPL79574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061385.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000011.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02525"/>
    <dbReference type="EnsemblBacteria" id="KPL79574">
        <property type="protein sequence ID" value="KPL79574"/>
        <property type="gene ID" value="ADN00_02525"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0080132">
        <property type="term" value="F:fatty acid alpha-hydroxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006694">
        <property type="entry name" value="Fatty_acid_hydroxylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014430">
        <property type="entry name" value="Scs7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12863">
        <property type="entry name" value="PTHR12863"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04116">
        <property type="entry name" value="FA_hydroxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="8" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="6" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="113"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="141"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="domain" description="Fatty acid hydroxylase" evidence="10">
        <location>
            <begin position="65"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL79574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="211" mass="24831" checksum="D660D7028E249EB9" modified="2016-01-20" version="1">MSTIQVDNSENPIRLFKSDFLEFFTHISPLAVVIIWLPVVFFFLVRGILQRPAQSGWVFIPAAYALGLFLWTLAEYLLHRFLFHHHPKNPAHERIFFLFHGVHHAQPRVKTRLVMPPVVSIPLALLFYGLFWLVLGVLLSAGHWVGPMFSGFITGYLMYDLTHYATHHFNFRSGYFKMVRKHHMHHHFQTPEQRFGVSSPLWDYVFKTYPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XIH4</accession>
    <name>A0A0P6XIH4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_12970</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000028">
        <property type="protein sequence ID" value="KPL75297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063447.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000028.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12970"/>
    <dbReference type="EnsemblBacteria" id="KPL75297">
        <property type="protein sequence ID" value="KPL75297"/>
        <property type="gene ID" value="ADN00_12970"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL75297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="526" mass="58622" checksum="6AD7734C0EF84748" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKI0</accession>
    <name>A0A0P6XKI0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_16080</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064061.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16080"/>
    <dbReference type="EnsemblBacteria" id="KPL72011">
        <property type="protein sequence ID" value="KPL72011"/>
        <property type="gene ID" value="ADN00_16080"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3651"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.45.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.43.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.465.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016166">
        <property type="entry name" value="FAD-bd_PCMH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036318">
        <property type="entry name" value="FAD-bd_PCMH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016167">
        <property type="entry name" value="FAD-bd_PCMH_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016169">
        <property type="entry name" value="FAD-bd_PCMH_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016164">
        <property type="entry name" value="FAD-linked_Oxase-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004113">
        <property type="entry name" value="FAD-linked_oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006094">
        <property type="entry name" value="Oxid_FAD_bind_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016171">
        <property type="entry name" value="Vanillyl_alc_oxidase_C-sub2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02913">
        <property type="entry name" value="FAD-oxidase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01565">
        <property type="entry name" value="FAD_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55103">
        <property type="entry name" value="SSF55103"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56176">
        <property type="entry name" value="SSF56176"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51387">
        <property type="entry name" value="FAD_PCMH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD-binding PCMH-type" evidence="1">
        <location>
            <begin position="119"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="578" mass="65850" checksum="CE50E61F31F23F7E" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XL10</accession>
    <name>A0A0P6XL10_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glyco_transf_28 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09715</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76870.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062806.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09715"/>
    <dbReference type="EnsemblBacteria" id="KPL76870">
        <property type="protein sequence ID" value="KPL76870"/>
        <property type="gene ID" value="ADN00_09715"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008194">
        <property type="term" value="F:UDP-glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030259">
        <property type="term" value="P:lipid glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033072">
        <property type="term" value="P:vancomycin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd03784">
        <property type="entry name" value="GT1_Gtf-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004276">
        <property type="entry name" value="GlycoTrans_28_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002213">
        <property type="entry name" value="UDP_glucos_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03033">
        <property type="entry name" value="Glyco_transf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00201">
        <property type="entry name" value="UDPGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_transf_28" evidence="1">
        <location>
            <begin position="3"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76870.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="421" mass="45452" checksum="0B4875F9420013AF" modified="2016-01-20" version="1">MKITIFAAGSQGDIQPCVALGKGLQRAGYQVSLAAPEDFAEFVQRHALEFRPLRGDVQKIMASDTGREFMQTGGQNPLTSIRTMRVLLAPVIREMTADAYTACQDADGLICLGVVSAFGKSIAEALQIPMLNIEPTPLLPSRSFPAPSWPIQRNLGGLHNTLSGRAMLQVVWYWYQPFVNDLRRRLGLPPFSGSRFYRALRDTPLIGAYSPGIIPQPPDWPEHAHVSGYLFLDSLADWQPPAGLTEFLEAGEPPVYIGFGSMSGQSPEVLAELVINALAQSGQRGVLLTGWGGLRPEMLADNIFVLNSAPHNWLFPRMAAVVHHGGAGTTAEGLRAGVPSIIVPFILDQPFWGARVQSMGLGPAPIPQKNLTAESLAAAITSAVTDTAMRERARLTGEAIRAEDGVGSAVKLVQRYFGDPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XL42</accession>
    <name>A0A0P6XL42_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">2-dehydropantoate 2-reductase</fullName>
            <ecNumber evidence="2">1.1.1.169</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Ketopantoate reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_10030</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>(R)-pantoate + NADP(+) = 2-dehydropantoate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:16233"/>
            <dbReference type="ChEBI" id="CHEBI:11561"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15980"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.169"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; (R)-pantothenate biosynthesis; (R)-pantoate from 3-methyl-2-oxobutanoate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the ketopantoate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.169" evidence="2"/>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062865.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10030"/>
    <dbReference type="EnsemblBacteria" id="KPL76925">
        <property type="protein sequence ID" value="KPL76925"/>
        <property type="gene ID" value="ADN00_10030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2468"/>
    <dbReference type="UniPathway" id="UPA00028">
        <property type="reaction ID" value="UER00004"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008677">
        <property type="term" value="F:2-dehydropantoate 2-reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003710">
        <property type="entry name" value="ApbA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013752">
        <property type="entry name" value="KPA_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013332">
        <property type="entry name" value="KPR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02558">
        <property type="entry name" value="ApbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08546">
        <property type="entry name" value="ApbA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00745">
        <property type="entry name" value="apbA_panE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0566">Pantothenate biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ApbA" evidence="3">
        <location>
            <begin position="7"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="ApbA_C" evidence="4">
        <location>
            <begin position="179"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL76925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="306" mass="33465" checksum="F4B497CDB9A72F45" modified="2016-01-20" version="1">MPDIHNVAILGAGAMGAYFAAQFASAPGFSTTLIASGERRERLNRDGLTVNGQTYHIPAIDPAQATTTADLILVALKHHQLADAVSQLDRLVGEQTIFLSVMNGLESEEIIAARYGAEKVLYAISLGIDAVREGNRVTYTRPGTHYFGEARNEQISPRVHRVQQAFDRAGIRHQTPTDMLRMLWWKFMINVGVNQASAVMRAPYGVFHNNPHAQALMEALMREVVALAQVAGVNLSEQDITDWYPVLRQLSPLGKTSMLQDVEAGRKTEVEMFGGKVVALGKAHSVPTPVNETVVQIIRVLEETGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XL51</accession>
    <name>A0A0P6XL51_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_00105</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL80995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060925.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80995">
        <property type="protein sequence ID" value="KPL80995"/>
        <property type="gene ID" value="ADN00_00105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="229"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="260"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="305"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="335"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="358"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="386"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="534" mass="59710" checksum="9BA242B087BE264B" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XLU1</accession>
    <name>A0A0P6XLU1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062670.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09030"/>
    <dbReference type="EnsemblBacteria" id="KPL77272">
        <property type="protein sequence ID" value="KPL77272"/>
        <property type="gene ID" value="ADN00_09030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="1">
        <location>
            <begin position="2"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="154" mass="17729" checksum="3A399DA1033C8CF3" modified="2016-01-20" version="1">MPLLKYTLCFLTHQDSILMLKRNRPPNRGLWNGVGGHIEAGETPSQSILREVKEETGIEIPAARYAGILTWSGFEIEDGGLYIFTAQAPSFNIQQSEEGWLAWKPKDWVFTSPEVVSNIHVFGPEVFQNSHTRQYHFIYDRGQIKEYSFRELPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XML9</accession>
    <name>A0A0P6XML9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_18920</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70174">
        <property type="protein sequence ID" value="KPL70174"/>
        <property type="gene ID" value="ADN00_18920"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3095"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010064">
        <property type="entry name" value="HK97-gp10_tail"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04883">
        <property type="entry name" value="HK97-gp10_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01725">
        <property type="entry name" value="phge_HK97_gp10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="125" mass="13566" checksum="995419461A5B28C7" modified="2016-01-20" version="1">MAAQFPVATEAVVKKTTQEIEKISKESMEGPKSGRLYSRGKKTHHASAPGEPPAVDSGNLANSIQSEVSMQANGPRGVVFTNTEYAVGLEFGTRKMAARPFMKPAADRMRPIYLSALKKIEESLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XNU4</accession>
    <name>A0A0P6XNU4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">VOC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_07205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78251.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062306.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07205"/>
    <dbReference type="EnsemblBacteria" id="KPL78251">
        <property type="protein sequence ID" value="KPL78251"/>
        <property type="gene ID" value="ADN00_07205"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="2"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78251.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="225" mass="25169" checksum="7BD7D14A0BE4A25A" modified="2016-01-20" version="1">MRFESLTLETRDVQAITTFYTEIMGLVATRAESEQTSFQIGATELTFKQFTGDQASSYHFAIEIPPNQIYEAGAWLASRVPILPFQGKTLVEHQAWNAKAYYFTDAGGNVVELIARGAAVKSARKKAFNQTSLLRVSEVGLVVPSVKRFCEQLNVLMEIPYYQEPSEDFAAMGDEEGLLIVSVSGRGWIPINLPARPHTIILRMKGNVNRRWIPNGLPYILDSHT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XPZ0</accession>
    <name>A0A0P6XPZ0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_16785</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064206.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16785"/>
    <dbReference type="EnsemblBacteria" id="KPL71363">
        <property type="protein sequence ID" value="KPL71363"/>
        <property type="gene ID" value="ADN00_16785"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.416"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL71363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="251" mass="27846" checksum="FFB8E92E33468C6A" modified="2016-01-20" version="1">MSKLDEYQRVLSALTDWEPYLLEQSGLPGPRGNIELAMAFSKEGTLVDFQRLLDENPAQTAPVNDPCEFLAFCGAVGLGRCLAQGDLSQTARLRELANDPRWRMREAVCMALQCWGDVNMDALLDEMRLWAAGTCLEKRAAAAAICEPRLLKQAGHAGRVFDILERAMEGITTGAERKSEGYIALRKGLAYCWSVAVAAYPEVGKAAFERWLTCADQDARWVLKQNLTKNRLVKMDAGWVKAMQMRLAEGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XPZ6</accession>
    <name>A0A0P6XPZ6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sugar ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_06125</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78799.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062083.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78799">
        <property type="protein sequence ID" value="KPL78799"/>
        <property type="gene ID" value="ADN00_06125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="68"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="137"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="180"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="237"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="69"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL78799.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="273" mass="31646" checksum="F5BBD2348CE560BA" modified="2016-01-20" version="1">MKKITFSQVLNFAVILLFAFIMLAPYLWMITTSLKPRNMMGEPPYLFPTYFRFENYQIAWKAAPFLRYYINTLIVAVAVIASRIVLASLAAYSFAIMKFKGRDLIFLLFLGTMMIPFQSIIIPSYQLARDFNWFNTYQVLIVPRMVDAFSIFLLRQNFISIPKDYLDAAKMDGCNDWQTLWKIVFPLATPTVLTMSLFTFLFIWNDFLWPLLVANAEKMRVIQVGLQAFSGRYQVEWTYMMAGTVMATILPILLFFLAQKQFISGIMKSGIKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQ40</accession>
    <name>A0A0P6XQ40_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Macrolide ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_06495</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062149.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78854">
        <property type="protein sequence ID" value="KPL78854"/>
        <property type="gene ID" value="ADN00_06495"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="11"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="47"/>
            <end position="54"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL78854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="230" mass="25102" checksum="8476AD55E803E4A2" modified="2016-01-20" version="1">MIESQPNNDVIIANDLRKIYKMGEIEVRALDGVTFNIQKGEVVAIMGPSGSGKSTMMNILGCLALPSSGDYILDGERVSDLDDDQLADIRNRKVGFVFQSFNLLSKQTALANVELPMRYAGIPAKERVDRATAALFAVGLGNRLHHKPTELSGGQQQRVAVARALINDPAIIMADEPTGNLDSKSGVEIMDLILSLNRDRGTTIIIVTHDPRIGEQAQRVIRLVDGRRVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQP7</accession>
    <name>A0A0P6XQP7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FlpD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_04460</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061752.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04460"/>
    <dbReference type="EnsemblBacteria" id="KPL79119">
        <property type="protein sequence ID" value="KPL79119"/>
        <property type="gene ID" value="ADN00_04460"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003813">
        <property type="entry name" value="MvhD/FlpD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02662">
        <property type="entry name" value="FlpD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FlpD" evidence="2">
        <location>
            <begin position="9"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="147" mass="16723" checksum="EABBF65CF947E78E" modified="2016-01-20" version="1">MTSTWKPRIVLFQCQWCLFSEADQKWVDTQRPRNVRLVKVPCTGRISPLYILNALQGGADGVLVSGCKPEMCHFKEGNLGARRQLDEFANFLEYAGLEEGRVHFAWLDVQERGRIQQELADMEARLVEMGPSERMKTRAPLKEGGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XR27</accession>
    <name>A0A0P6XR27_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_16210</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064086.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16210"/>
    <dbReference type="EnsemblBacteria" id="KPL72030">
        <property type="protein sequence ID" value="KPL72030"/>
        <property type="gene ID" value="ADN00_16210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="6"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="40"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL72030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="266" mass="29460" checksum="AB5B6CAAB3FA3DF5" modified="2016-01-20" version="1">MSTPILSFENVVFRYQPQDHTVLNELSLQIEPASITAILGPNGVGKTTLLLLGLGWRRPQSGQVLLDGKDLLSYRRNELGQRIGLVPQTEHIAYDYSILEYVLLGRAPYLMPLEMPGEADCRAAQRALATVGLAGISDRPVTELSGGERQLVLVARALAQQPRLLLLDEPTNHLDLGNKIHLLELLRDLKDSGVTVVFTTHEPEVAAVLADQLVLMRDGKVQHAGSLQEQFTSERLSETYDTPVEVHEVAGRRVVIWRNGADKKHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XSV8</accession>
    <name>A0A0P6XSV8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphoesterase</fullName>
            <ecNumber evidence="2">3.1.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_06885</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the metallophosphoesterase superfamily. YfcE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.-" evidence="2"/>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78208.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062247.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06885"/>
    <dbReference type="EnsemblBacteria" id="KPL78208">
        <property type="protein sequence ID" value="KPL78208"/>
        <property type="gene ID" value="ADN00_06885"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110165">
        <property type="term" value="C:cellular anatomical entity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024654">
        <property type="entry name" value="Calcineurin-like_PHP_lpxH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000979">
        <property type="entry name" value="Phosphodiesterase_MJ0936/Vps29"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11124">
        <property type="entry name" value="PTHR11124"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12850">
        <property type="entry name" value="Metallophos_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00040">
        <property type="entry name" value="yfcE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallophos_2" evidence="3">
        <location>
            <begin position="16"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008950"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF12850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL78208.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="207" mass="23638" checksum="18010EE155344205" modified="2016-01-20" version="1">MSDVEILNLPDGGVLRIGVVADTHVPDRVVGLHPALLSTLQQEKVDYIFHAGDICDEQIETQLSKVAPVRAVLGNRDWLYGRKLPHVYRFEVNGTRGVLMHGQGTFLDYWWDKVWYTLEGYRFARYRKTLEKMAPDCDLFIFGHTHRAENMVEDGRWFFNPGCASSPKYRRGPSIGVLQFELGKAPQGKIITLDGAFLEGRNWKTNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XT36</accession>
    <name>A0A0P6XT36_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Copper-sensing transcriptional repressor CsoR family protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_02200</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000009">
        <property type="protein sequence ID" value="KPL79796.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061327.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000009.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79796">
        <property type="protein sequence ID" value="KPL79796"/>
        <property type="gene ID" value="ADN00_02200"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2762"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003735">
        <property type="entry name" value="Metal_Tscrpt_repr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038390">
        <property type="entry name" value="Metal_Tscrpt_repr_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33677">
        <property type="entry name" value="PTHR33677"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02583">
        <property type="entry name" value="Trns_repr_metal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79796.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="90" mass="10269" checksum="A1E66FBBD7C5B37B" modified="2016-01-20" version="1">MHQKDTVVRRLKTIEGHIRGISRMVEEDTYCVDVLNQINAVQASLNKISNLILDDHLRHCLTTAVRGDNPEDTERVLKEITQLFEAATKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XU59</accession>
    <name>A0A0P6XU59_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09840</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062828.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76893">
        <property type="protein sequence ID" value="KPL76893"/>
        <property type="gene ID" value="ADN00_09840"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2426"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133229" evidence="1">
        <location>
            <begin position="34"/>
            <end position="1130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="1130" mass="121459" checksum="56B1B05D3CC12B60" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUX9</accession>
    <name>A0A0P6XUX9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_09010</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062666.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09010"/>
    <dbReference type="EnsemblBacteria" id="KPL77268">
        <property type="protein sequence ID" value="KPL77268"/>
        <property type="gene ID" value="ADN00_09010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="7"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="86"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="144" mass="15798" checksum="5DB21F70A94C9DC8" modified="2016-01-20" version="1">MIVKDVMRSKFLCISPKSSLRLAAEIMVREGVETLFVVNGEQLVGAIGIRDLFTSPVPASYGRPMQRQIENTLIQKWDNAPVENLMTPYVLGVTEESPLMSAATLMINQGKHPLAVTKDQKIVGIIDRIDIVKYLLGLGASASE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-04-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XV07</accession>
    <name>A0A0P6XV07_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Response regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_04035</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79059">
        <property type="protein sequence ID" value="KPL79059"/>
        <property type="gene ID" value="ADN00_04035"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="110" mass="11886" checksum="439BC91887B92CAA" modified="2016-01-20" version="1">MKMAADVLGHQIVTATCVSEAIQLAGSQTPDLIFADLGCLQDMEGNAFIHQFCHSATIEGVPVIIVSAGWSGDDAQRVEKNGHCCFMNKPVTMDQMDKTVKKYVQSASRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XV28</accession>
    <name>A0A0P6XV28_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_04240</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79086.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061714.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79086">
        <property type="protein sequence ID" value="KPL79086"/>
        <property type="gene ID" value="ADN00_04240"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.205"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="3"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="250"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="35"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL79086.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="505" mass="56893" checksum="EFC27FCB3D3DD682" modified="2016-01-20" version="1">MLLEMKGITKFFGPVKALDNVDFTVADSEIHGLLGENGAGKSTLMNILAGAIHPTQGEIFIDGNRIEEMSITKSNELGIRFIHQELNLVNDLTVFENLFLGQELLTKGGFLDKKQMIARSAEVLKRIKLDIDPLTLVDDLEASRKQLVEIAKALLFESKLIIMDEPTTALTNKEIEILFDIMRSLKDHGLSIIFISHKMPELFEICDKYTVLRDGQFIDSGYFKDIDEQKATNLLVGRSIVDSQLVKEDVRGDVIFTAQSLTCKGYFENVSFDLRKGEVLAITGLHGDGRSELSEALFGARALTSGSITLHGKELKLHSIRQVMKAGIGMIPRNRKERSIIKDLSILNNLSIAYFISKHNKVFISRKEELERFRRNQKITDIKVDDPDNYITSLSGGNQQKVIVSRWLELDSDVYIMDNPTQGIDVGAKFEIYKLINELARRGKSLIIFSAEFPEIYKIADRCIVMYKGHINAQLNRDELNEVNVMYYATGSNSEGFNGKSVKKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-08-12" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XWI1</accession>
    <name>A0A0P6XWI1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SpoU_methylase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_02165</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000009">
        <property type="protein sequence ID" value="KPL79808.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79808">
        <property type="protein sequence ID" value="KPL79808"/>
        <property type="gene ID" value="ADN00_02165"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008173">
        <property type="term" value="F:RNA methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001537">
        <property type="entry name" value="SpoU_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00588">
        <property type="entry name" value="SpoU_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SpoU_methylase" evidence="1">
        <location>
            <begin position="13"/>
            <end position="157"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79808.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="163" mass="17789" checksum="CEDA5BAA21C144FB" modified="2016-01-20" version="1">MTRTSQTAPVPRIEVMLDNIRSTFNVGAMFRSCDGAQIAHIHLCGTSPTPEHPKIAKTSLGAELSVPWSYHRNGLQAAQHLKDRGYLVWSLEGGENAVSLFKSRFPSVQPPLLLVVGNEVTGVDPGILRISDQIVYLPMSGAKESLNVAIAFGIAVYFLRFKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XXC2</accession>
    <name>A0A0P6XXC2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01345</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061164.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01345"/>
    <dbReference type="EnsemblBacteria" id="KPL80521">
        <property type="protein sequence ID" value="KPL80521"/>
        <property type="gene ID" value="ADN00_01345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13673">
        <property type="entry name" value="Acetyltransf_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="121"/>
            <end position="264"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="264" mass="29736" checksum="B83DBC78B28C4AFB" modified="2016-01-20" version="1">MKLEELREIFDHQQRVDVDYPDIQREDGPLTVRHINLRPAERGFVIYSRLDESNADAAIEAEIARFRAAGQDFTWKVYDHDTPPDLKARLTTRGFSAQELEAVLVLDMDSAPPAFFHPPAQTARRLSDPEAVLAAFEAVEVPVWQDEGMRELGALLVDEMLANPQELSFFAVYAQEQPVSLAWIRYHPGTQFASLWGGSTLEAYRGQGAYQALLAARAIEARQRGARFLTVDASPMSEPILLRRGFQPISRAQDFEYTFEAGPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XY36</accession>
    <name>A0A0P6XY36_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">F420-dependent NADP reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_00245</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060949.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00245"/>
    <dbReference type="EnsemblBacteria" id="KPL81015">
        <property type="protein sequence ID" value="KPL81015"/>
        <property type="gene ID" value="ADN00_00245"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3443"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070967">
        <property type="term" value="F:coenzyme F420 binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006740">
        <property type="term" value="P:NADPH regeneration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010185">
        <property type="entry name" value="NpdG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028939">
        <property type="entry name" value="P5C_Rdtase_cat_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03807">
        <property type="entry name" value="F420_oxidored"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01915">
        <property type="entry name" value="npdG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F420_oxidored" evidence="1">
        <location>
            <begin position="11"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL81015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="227" mass="23765" checksum="C3A6FF93852D062A" modified="2016-01-20" version="1">MKDPILDNIKTISIIGGTGKEGKGLAYRWAKAGYQIIIGSRSNEKAETAAAAVRELLDGVGVVVGKENAAAAQEGDIVVLTVPFAAHVSMLEYLKPYLQGKTLIDVTVPLVPPKVTRVQMPPAGSAGLEAQQVLGEGVAVVTAFQNISYENLLEGEDVDCDILVCGSSKEARETVLALVKEAGLIGWDAGPLENSVVVEGLTSILIGINKRYGVTSSGIRITGVPLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XY49</accession>
    <name>A0A0P6XY49_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_00450</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060985.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL81043">
        <property type="protein sequence ID" value="KPL81043"/>
        <property type="gene ID" value="ADN00_00450"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL81043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="419" mass="48156" checksum="A75232D34E933570" modified="2016-01-20" version="1">MRILFLSQIVPWPLDAGPKIKSWNVLQHLKEAGHEVWFVSFVRAEEEKYIPKVKELLDHAWFVPIRRSRINDLYFLIKSRFTGKPFLVERDHLGSMRDLVKKLIGENHFDILHADQLTMAQFFTMPVGDSDGGSNVDSPKRVFDAHNATWKILERAADESKAPMKWFYQDEMRRLQQFERKIITDFDHTFTVSEIDKRSFLELSDNPQAISPKITPIPIGINSRSYERATNGSPSTPNQIVTLGSLNYPPNADGIRWFIREVYPFVLQKKTDAFLWVIGKNPPSDFFEYEKEYSDHLKVTGYVDDLDSYFNQAALAVVPVKVGGGMRVRILECFARNVPVITTTIGAEGIEVSDGDNIFIEDEEEKFAQRIIDVLGNEPLRHKVVGNAKDLLLKKYDWSVVLRELERVYCDLVSTQVGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XY98</accession>
    <name>A0A0P6XY98_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_07455</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062355.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07455"/>
    <dbReference type="EnsemblBacteria" id="KPL78292">
        <property type="protein sequence ID" value="KPL78292"/>
        <property type="gene ID" value="ADN00_07455"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="4"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="132" mass="14449" checksum="77F29090393F55FF" modified="2016-01-20" version="1">MEPRISIITLGVADLERSIRFYRDGLGLPMRAGSVGIAFFETKGTWLALYPREALAEDANQSPAGSGFNGFTLAHNLRSKEEVDALLAQAASAGAQIVKPAQDTDWGGYSGYFKDPDGFLWEIAWNPYFSIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y090</accession>
    <name>A0A0P6Y090_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sugar ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_05730</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062010.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78740">
        <property type="protein sequence ID" value="KPL78740"/>
        <property type="gene ID" value="ADN00_05730"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1622"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="161"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="207"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="267"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="69"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL78740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="299" mass="33740" checksum="3342E34CC817116B" modified="2016-01-20" version="1">MRYSRKDRATSIALVLPTIVVMFIFIYGFIGFTGYASFSNWKKLKPDFTFIGFENYIKLFENQRFIIDMRNTFTFTVLFLIATILLGFFLAFLLEQKVKGESIFRNIYLFPMALSYIVTGVVWRWLLSPGTESTGPLGVNLLFDNLGLGFLKNGWYTDPNIGIRAVVIAATWQMAGYVMALYLAGMRGIPDELKEAARVDGANEFDVYRYIIIPLLRPITLSAVIILGHMSLKIYDLVVSMTGPGTGFSTDVPALFMFDTTFRGNRFAQGSSIAMVLLIMVAVLVVPYLVSSYRKEVVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y106</accession>
    <name>A0A0P6Y106_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nitro_FeMo-Co domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_06270</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06270"/>
    <dbReference type="EnsemblBacteria" id="KPL78886">
        <property type="protein sequence ID" value="KPL78886"/>
        <property type="gene ID" value="ADN00_06270"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003731">
        <property type="entry name" value="Di-Nase_FeMo-co_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036105">
        <property type="entry name" value="DiNase_FeMo-co_biosyn_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02579">
        <property type="entry name" value="Nitro_FeMo-Co"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53146">
        <property type="entry name" value="SSF53146"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitro_FeMo-Co" evidence="2">
        <location>
            <begin position="9"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="132" mass="14473" checksum="7D4AF9EA934DF9C4" modified="2016-01-20" version="1">MKIAVITDDGKTISQHFGRAQYYLILTIEEGQVVAREMRNKMGHSHFVSQSPAEESHGAGHGMDASSHNKHVSMAETIADCKVLLCGGMGMGAYQSMTQLNIQPVVTTHRDIDEAVQAFIDGKLIDHTELLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y1P7</accession>
    <name>A0A0P6Y1P7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">MurNAc-LAA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_03425</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061563.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03425"/>
    <dbReference type="EnsemblBacteria" id="KPL78959">
        <property type="protein sequence ID" value="KPL78959"/>
        <property type="gene ID" value="ADN00_03425"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008745">
        <property type="term" value="F:N-acetylmuramoyl-L-alanine amidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009253">
        <property type="term" value="P:peptidoglycan catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02696">
        <property type="entry name" value="MurNAc-LAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002508">
        <property type="entry name" value="MurNAc-LAA_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01520">
        <property type="entry name" value="Amidase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="MurNAc-LAA" evidence="2">
        <location>
            <begin position="84"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="269" mass="29629" checksum="422E6DD89B76D2A8" modified="2016-01-20" version="1">MDENPTSASPAPRPAQRGSINFSIIQSFQSVILVGMILATLFTLWTPSTLFSSQSIREILTSVQATEMVQASTPTPGAATNQRIGIVAGHWGNDPGAVCPDGLTEAEINLRIATLVKQILVEQGYQVDLLQEFDEKLYQYQAIALISIHADTCQYIDDSKTGFKVAAAQSSAYPEKSQRLNSCLIHRYQQATNLPFDFNTITTDMREYHTFSEIHSNTTAAIIEVGFMNLDREFLTKHPDIAAQGIANGILCYTRNESIPEAELPINSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y2A8</accession>
    <name>A0A0P6Y2A8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_04105</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061690.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04105"/>
    <dbReference type="EnsemblBacteria" id="KPL79069">
        <property type="protein sequence ID" value="KPL79069"/>
        <property type="gene ID" value="ADN00_04105"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.176"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018658">
        <property type="entry name" value="DUF2089"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09862">
        <property type="entry name" value="DUF2089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="131" mass="14698" checksum="DA54888EEA1DCD33" modified="2016-01-20" version="1">MYPQPAQCPVCGAELLVTRLHCRNCDTVIEGHFHAPVDHFENLSDEQVSFVLSFIRCEGRFNRLEEELGVSYPTLRNRLNEVVRALGFEPGKEEAQAVKVSADERMKILDDLAAGRISSQDAKELLRGRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y3X1</accession>
    <name>A0A0P6Y3X1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_02375</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000010">
        <property type="protein sequence ID" value="KPL79663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061358.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000010.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02375"/>
    <dbReference type="EnsemblBacteria" id="KPL79663">
        <property type="protein sequence ID" value="KPL79663"/>
        <property type="gene ID" value="ADN00_02375"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2692"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010349">
        <property type="entry name" value="Asparaginase_II"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42110">
        <property type="entry name" value="PTHR42110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06089">
        <property type="entry name" value="Asparaginase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="345" mass="37271" checksum="FD8C2D4AA83875AF" modified="2016-01-20" version="1">MPNSFIPVMEVTRGTLVESVHFGAAAVVDPAGRLIASLGDPGLVTYLRSSAKPFQALHFLELGGAQHFHWSDAEVALMCASHSGTDLHYQTVSSMQAKTGLQEADLQCGTHPPFHKPTALALAARGEAPTPNRHNCSGKHTGMLAQCVLRGLSKQNYLDFNHPVQQANLQTIAEMCDVPAEQIGLDIDGCSAPVHALPLYNAALGYARLSDPAGLPAERAEACRLITRAMRAHPEMVAGPDRLDTHLMRAAQGKLFSKMGAEGYQAVGVLPQAIPGRPALGITIKIADGDSDGRARNVVTLEILRQLGLTVPAVEGLEAFWDWKVRNWRKMEVGELRPCFQLQFH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y5J8</accession>
    <name>A0A0P6Y5J8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Pyridine nucleotide-disulfide oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_09695</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062802.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09695"/>
    <dbReference type="EnsemblBacteria" id="KPL76867">
        <property type="protein sequence ID" value="KPL76867"/>
        <property type="gene ID" value="ADN00_09695"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2396"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028261">
        <property type="entry name" value="DPD_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00037">
        <property type="entry name" value="Fer4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14691">
        <property type="entry name" value="Fer4_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="284"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="826"/>
            <end position="855"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL76867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="896" mass="98335" checksum="D16B943F68FC6EB0" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y5Z8</accession>
    <name>A0A0P6Y5Z8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Histidine kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_10615</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062973.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10615"/>
    <dbReference type="EnsemblBacteria" id="KPL77013">
        <property type="protein sequence ID" value="KPL77013"/>
        <property type="gene ID" value="ADN00_10615"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="entry name" value="HATPase_C"/>
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        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017205">
        <property type="entry name" value="Sig_transdc_His_kinase_ChrS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037434">
        <property type="entry name" value="STHK_ChrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
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    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="52"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
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            <begin position="89"/>
            <end position="112"/>
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    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="124"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
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            <begin position="148"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="319"/>
            <end position="409"/>
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    </feature>
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            <begin position="173"/>
            <end position="214"/>
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    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="244"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL77013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="412" mass="45396" checksum="468A2FFE46AD6C4C" modified="2016-01-20" version="1">MPKQNWLRTLLSLDDPEVRTVRPFFWLLTVVLLGLFGMTLAQNPQMLRRPGLFAVFSLLFALHLLLHWLSPWVIYIQKQAFTYLALQGVLAFTLSLIPPVPSLGQGLFLALVGETVGIFRRSRVTVVGLVIFLALSSISIWVKGGWDAARGWLILAGPMTLFVVVYVLLYVRQSELREEAQALAAELAKANQQLKEYAEQIETLTLAAERQRMARELHDTLAQGLVGLTLQLEAADSHLGHQNLERAQAIIRQAMERARTTLAEARQVIDALRSDLPGGPNLEAALRDEINRFCVATGIHCEVSLDLPPSLPQAAREHLPRIVGEGLANIARHARAKNAWVRLETTETRLSLEIGDDGEGFDTLAVEGSSGHYGLVGMRERARLAGGSLEVFSQPGQGTRLAAQFPLSAEDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y6P8</accession>
    <name>A0A0P6Y6P8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_08965</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77260.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08965"/>
    <dbReference type="EnsemblBacteria" id="KPL77260">
        <property type="protein sequence ID" value="KPL77260"/>
        <property type="gene ID" value="ADN00_08965"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4027"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
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    <feature type="transmembrane region" description="Helical" evidence="1">
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    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="607"/>
            <end position="628"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77260.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="634" mass="70810" checksum="BF2501D82B8F95A0" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YA94</accession>
    <name>A0A0P6YA94_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SIS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05790</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
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        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78750.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062021.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78750">
        <property type="protein sequence ID" value="KPL78750"/>
        <property type="gene ID" value="ADN00_05790"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1634"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901135">
        <property type="term" value="P:carbohydrate derivative metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05013">
        <property type="entry name" value="SIS_RpiR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035472">
        <property type="entry name" value="RpiR-like_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
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    </dbReference>
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    </dbReference>
    <dbReference type="Pfam" id="PF13580">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
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        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SIS" evidence="1">
        <location>
            <begin position="32"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78750.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="245" mass="26516" checksum="8A8334899AF9F219" modified="2016-01-20" version="1">MAGLKYFDEIMPILQKAMKTQAENVRRLGEWMADAIANDHLIYVFGAGHAGIISEEMCYRAGGLVPVNAILAPGLTLNTRPLTLETQLERLPGLAKLVFESAGVKAGDVLIVHSNSGRNTVAIEMAEIARDNGVRVVALTSIAHSQSVESRHLKGYRLMDVADLVIDNCGIPGDAVVKLDQFDQRCGATSTVVGATLMNAAICEAVELLLQRGIVPPVTKSANLDNSDEHNQKIWDHYAGRLIYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YBD2</accession>
    <name>A0A0P6YBD2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Radical SAM core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_04120</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04120"/>
    <dbReference type="EnsemblBacteria" id="KPL79235">
        <property type="protein sequence ID" value="KPL79235"/>
        <property type="gene ID" value="ADN00_04120"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.180"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023874">
        <property type="entry name" value="DNA_rSAM_put"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21180:SF9">
        <property type="entry name" value="PTHR21180:SF9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01102">
        <property type="entry name" value="Uncharacterised_Radical_SAM_Su"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Radical SAM core" evidence="5">
        <location>
            <begin position="25"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL79235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="362" mass="40585" checksum="24C451ED094D13E0" modified="2016-01-20" version="1">MEVESPGACPLKQAGDLPIQMAALPNGKRIPLLKTLLTAVCENNCTYCAFRRERDFRRESFQPDELADAVMRLWRAKVIEGVFLSSGVAGGGARTQERLIAAAEILRHRRGFTGYLHLKIMPGSEYAQVLRSMQLADRVSVNLEAPNQSRLNQLAPDKTFLGQLLQPLKWVDEIRHNQEPQAGWKGRWPSSTTQFVVGAVGESDLELLETSAHLHHGLHLSRVYFSGFSPVRGTPLEDHPALDSWREHRLYQADFLLRDYGFELEDLPFEGAGELPRDIDPKLAWARAHLIDAPVEVNQADLQDLMKVPGIGPQGARAIVSARRQERLRFLGDLRRLGIAAERAAPFVAFSGKRAAYQLRLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YBL7</accession>
    <name>A0A0P6YBL7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_03075</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000014">
        <property type="protein sequence ID" value="KPL79326.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061493.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000014.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79326">
        <property type="protein sequence ID" value="KPL79326"/>
        <property type="gene ID" value="ADN00_03075"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="45"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79326.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="63" mass="6962" checksum="24AA35FEDA935549" modified="2016-01-20" version="1">MAKKEKRSVSRVEESAAPVASRGRVSVSSEFNPDYSYIIKDLKRIGTLAVVFFVVLVALSFVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YBR2</accession>
    <name>A0A0P6YBR2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ADN00_02795</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase M29 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000013">
        <property type="protein sequence ID" value="KPL79381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061439.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000013.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02795"/>
    <dbReference type="EnsemblBacteria" id="KPL79381">
        <property type="protein sequence ID" value="KPL79381"/>
        <property type="gene ID" value="ADN00_02795"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2192"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1830.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035097">
        <property type="entry name" value="M29_N-terminal"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000787">
        <property type="entry name" value="Peptidase_M29"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02073">
        <property type="entry name" value="Peptidase_M29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0031">Aminopeptidase</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL79381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="367" mass="41278" checksum="84EC42FAA1812457" modified="2016-01-20" version="1">MTDIRLTKLADVLVNYSTKVRNGDWVHIRAGLPAMPLVQELYSSILKAGGKPTFSIVSDELEALVHEQASDEQLKWLSPLDEKIISEADVYMVIVAPENIRAMSRIDPARQQVRQSGRRKWMDTYLSRSANGDLRWVLTNYPCLSLAQDSGKSLRQYEDFFYAATFIDQPDPVKCWQQVHDDQARLINWLTGRKQVRIQGVNADLTLSIDGRRFLNSDGDCNMPSGEIFTSPVETSANGWVRFTYPAIHLGMEVESVRLEFKDGKVVSASAEKNQDFLLKMLDMDEGSRFLGELGIGTNFGIQEFSKDILFDEKIGGSFHLALGAGFGEAGGKNQSSLHWDLICDARVDTEMRVDGDLFYQNGKFMV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YF97</accession>
    <name>A0A0P6YF97_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Diphosphomevalonate decarboxylase</fullName>
            <ecNumber evidence="2">4.1.1.33</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ADN00_01255</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the diphosphomevalonate decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.33" evidence="2"/>
    <dbReference type="EMBL" id="LGCL01000003">
        <property type="protein sequence ID" value="KPL80844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061147.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01255"/>
    <dbReference type="EnsemblBacteria" id="KPL80844">
        <property type="protein sequence ID" value="KPL80844"/>
        <property type="gene ID" value="ADN00_01255"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1999"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004163">
        <property type="term" value="F:diphosphomevalonate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019287">
        <property type="term" value="P:isopentenyl diphosphate biosynthetic process, mevalonate pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005935">
        <property type="entry name" value="Mev_decarb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029765">
        <property type="entry name" value="Mev_diP_decarb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041431">
        <property type="entry name" value="Mvd1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18376">
        <property type="entry name" value="MDD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015950">
        <property type="entry name" value="Mev_P_decrbx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="SSF55060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01240">
        <property type="entry name" value="mevDPdecarb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP_kinases_N" evidence="8">
        <location>
            <begin position="92"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="domain" description="MDD_C" evidence="9">
        <location>
            <begin position="179"/>
            <end position="303"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF18376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL80844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="327" mass="35122" checksum="9E9B838DE7DE62CA" modified="2016-01-20" version="1">MSNLTATAVANANIAFIKYWGNRDAALRLPSNGSISMNLGGLQTRTTVYFDSSLTADTLTLNGQRATGPALERVSAFLDHFRHRAGVQTHARVESENNFPMGAGIASSASAFAALALAAASALDLNLSESQLSRLARLGSGSACRSVPGGFVEWHMGDSEAGSFAETIAPPSHWPLVDVIAVVQEHHKEVGSFQGQQLAHTSPFQQARVESAEERLQICRAAIQQRDFDALARVVELDSNMLHAVMCTSTPPLLYWQPISLQLMKEVIHLREQGLPVCYTLDAGPNVHILCEPSAVSSLRERLVQIPGILTILTAHPGGPARLVKST</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YFT3</accession>
    <name>A0A0P6YFT3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_00585</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061009.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00585"/>
    <dbReference type="EnsemblBacteria" id="KPL81063">
        <property type="protein sequence ID" value="KPL81063"/>
        <property type="gene ID" value="ADN00_00585"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3512"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL81063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="310" mass="34663" checksum="D27436F7F3B05E54" modified="2016-01-20" version="1">MIKVFDLTKAYGDRIAVDRVNFSIEAGKIIGFLGPNGAGKTTTMRMLTGFIPSTDGKIHIGDYDLDTHPLEAKKLIGYLPENVPLYTDMTVLEYLGFMAEIRQVKKNRNACMETLEKVQLENRANSLIGSLSKGMRQRVGLVQAILHNPPVLILDEPTVGLDPAQISEIRKLIQSLGEQHTILLSTHILPEVQQVCDRVLIINKGKLVAEDTPEQLQKQLHGNLCVKVQIANLNQELISTVEQLPGVLSARETAPNWLEITLQADTEIRPHIIRELVQNGAEILEFKHSVMDLEQIFLELTREELPAETN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GLD1</accession>
    <name>A0A0N8GLD1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PDDEXK_1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_15110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063871.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15110"/>
    <dbReference type="EnsemblBacteria" id="KPL72162">
        <property type="protein sequence ID" value="KPL72162"/>
        <property type="gene ID" value="ADN00_15110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038726">
        <property type="entry name" value="PDDEXK_AddAB-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12705">
        <property type="entry name" value="PDDEXK_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDDEXK_1" evidence="1">
        <location>
            <begin position="8"/>
            <end position="242"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="274" mass="32428" checksum="67170C94A5AEAE0E" modified="2016-01-20" version="1">MPLLPDFQFSQSSLQDYADCPRRFELRYILRQNWPALKSEPVLEMENWMDQGRQYHQMVQQYLLGIPEELLRPLITQPEGLQWWEQFIKVNPLAGLPDQVRLPEYRLSAPFHGFRLVAQYDLVCANPGEKAVIVDWKTSRHRPKKGWRERLQTRVYLFLLAEAGMRLNHNQPWQPEQMEMLYWFPAFPHEPERIPYSTARYQADREFLTDLINQIQSTPDGSFEKTADEKRCLYCPYRSLCERGDAAGNFLEEPSLSSGDLLELNLDEIEELEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GLE5</accession>
    <name>A0A0N8GLE5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">MPN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_15785</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the UPF0758 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063993.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72274">
        <property type="protein sequence ID" value="KPL72274"/>
        <property type="gene ID" value="ADN00_15785"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.862"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08071">
        <property type="entry name" value="MPN_DUF2466"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025657">
        <property type="entry name" value="RadC_JAB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001405">
        <property type="entry name" value="UPF0758"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020891">
        <property type="entry name" value="UPF0758_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30471">
        <property type="entry name" value="PTHR30471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04002">
        <property type="entry name" value="RadC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00608">
        <property type="entry name" value="radc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01302">
        <property type="entry name" value="UPF0758"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MPN" evidence="7">
        <location>
            <begin position="96"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL72274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="220" mass="24400" checksum="8C1B9EAEEC441646" modified="2016-01-20" version="1">MKYADLPKSEQPSHKIHEYGGKVLTPAELLALATFGMPSTSEKLGELYKEYGGLSRIPRHRILEIDGLGEKTADAIQAIVELTRREIVARKPDRVSIHCPQDAADLVMYEMSQLEVEQLRVILINTRNEVMRVVNLYQGTANSSNVRISEVFRDAIRENATGIILVHNHPSGNPDPSPEDVQLTRAAAESGKMLDIRVFDHIIVGANGTYRSLKEAGLGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GLV9</accession>
    <name>A0A0N8GLV9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Serine acetyltransferase</fullName>
            <ecNumber evidence="4">2.3.1.30</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ADN00_14700</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetyl-CoA + L-serine = CoA + O-acetyl-L-serine</text>
            <dbReference type="Rhea" id="RHEA:24560"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:58340"/>
            <dbReference type="EC" id="2.3.1.30"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-cysteine biosynthesis; L-cysteine from L-serine: step 1/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the transferase hexapeptide repeat family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.30" evidence="4"/>
    <dbReference type="EMBL" id="LGCL01000035">
        <property type="protein sequence ID" value="KPL73586.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063787.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000035.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14700"/>
    <dbReference type="EnsemblBacteria" id="KPL73586">
        <property type="protein sequence ID" value="KPL73586"/>
        <property type="gene ID" value="ADN00_14700"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2106"/>
    <dbReference type="UniPathway" id="UPA00136">
        <property type="reaction ID" value="UER00199"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009001">
        <property type="term" value="F:serine O-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03354">
        <property type="entry name" value="LbH_SAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001451">
        <property type="entry name" value="Hexapep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018357">
        <property type="entry name" value="Hexapep_transf_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045304">
        <property type="entry name" value="LbH_SAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010493">
        <property type="entry name" value="Ser_AcTrfase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042122">
        <property type="entry name" value="Ser_AcTrfase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005881">
        <property type="entry name" value="Ser_O-AcTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011004">
        <property type="entry name" value="Trimer_LpxA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00132">
        <property type="entry name" value="Hexapep"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06426">
        <property type="entry name" value="SATase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51161">
        <property type="entry name" value="SSF51161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01172">
        <property type="entry name" value="cysE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00101">
        <property type="entry name" value="HEXAPEP_TRANSFERASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="SATase_N" evidence="9">
        <location>
            <begin position="5"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF06426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL73586.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="254" mass="27401" checksum="C178A31D7145BB3F" modified="2016-01-20" version="1">MIGKFIELIREDVRSVYERDPAARSTLEILLTYPGLQAIWGYRIAHWLWTHRMKLAGRMLSNLMRGLTGVEIHPGAKIGRRFFIDHGMGVVIGETTTIGSDVTLYHGVTLGGVSTEKGKRHPDIGDGVVIGAGAKVLGAIEVGEYSRVGANAVVVKPVPANSVVVGVPGQVVMRSKPHPVSPDLHHEQLPDTIGASLTAVMARMEKMERKLRALEMGQAAVLVNGNGNGNGLSNGELVPHAPEHGMWRGEDFMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMY0</accession>
    <name>A0A0N8GMY0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_11385</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76554.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063137.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11385"/>
    <dbReference type="EnsemblBacteria" id="KPL76554">
        <property type="protein sequence ID" value="KPL76554"/>
        <property type="gene ID" value="ADN00_11385"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="154"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76554.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="235" mass="26194" checksum="4093AB431B868F6C" modified="2016-01-20" version="1">MKRLLATLRADVILQYRNGFYYAVLFVAALWVGLLSQVRGLDFGVILPLMVLMNLILGTFYFMAAMLLLEKGEGTLEAQVVSPLRAGEYLGSKVISLAALSLAENLAIVVVLRGLRFHPLPLVLGLLLAAAMYTLLGFLTAARYDSINSYFIPSIGWLLLLCLPVLRPLGIFDHWLMYLHPLQAPLTLMQAALEPLAAWQWLYGAGYALLWLGLVVWWSRKAFVRFVVIKEGVKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GN28</accession>
    <name>A0A0N8GN28_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062883.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76938">
        <property type="protein sequence ID" value="KPL76938"/>
        <property type="gene ID" value="ADN00_10120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="332"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="349" mass="40399" checksum="24A694369322B981" modified="2016-01-20" version="1">MASKLNQIVFQRKPEPTENAATLLVPQGWQMQGGILRANLYAERVSAQNIEAKVDLTVQKDAQGSVMLRVVPEMKYCDPRFLMGGFFPVGSNYGGMTVCPLMPPAQFLAQMMFPWAHPQAANAQMLDAQPWEEYANKYRAETAQYGLPTTYDGAQVTFAYEERGVRYKEKACVIIENLGQMAMGQWSNKSTYFYRAPFDEFEDWDPVLFLISRSWQFNPQWLAQERASQQMLTGSYNQALAAERQRGKKLLETQHHIQNTLNEMLDHQRVTNEEIRNDAYLTMTNQEEYINPYTNLVDYGSNQFNYRWVTEQGDEFYTNNESDNPNDADGVLNKNDWKRTQVRPRRPLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNJ2</accession>
    <name>A0A0N8GNJ2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_07200</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062305.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78250">
        <property type="protein sequence ID" value="KPL78250"/>
        <property type="gene ID" value="ADN00_07200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="281"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="465" mass="51531" checksum="0E6A923C77B3A608" modified="2016-01-20" version="1">MQERISFALAARIILPLCLLVALQIQPTPVAIQQSLAAQTQPDASPQDQAYGLEQALAREPWRAQLWEQVGFLRAQTGDDQRAVEAWEKSTFLSARGKEALAASYLRLGNREKALALWLDEIHRGRASESAFRQAVGLLREEGRFDEALQLVEDWRQARPESAEAAYTWAVLRLGAGEEPANLLDSLQTGRSYSPQAADALTAAIQALPAERDLAYQKMRLASVLARFGEWDAARGLLEQAVELEGASAEAWALLGEAIFQTGGDGWDAFERAQALNPTSAEIKVLLGLRYRQSGQPEIALGYLQEAARLQPYEGRWQVEIAETLADLGRISSALEHYTQAVAIAPRDSEIAKSLVRFTGNTSVGIQTVGIPAARNLILLDEQDPESQDLMGWLLMKQGDTTSAERFFHQALRLQADYLPAHYHLGQLYLLLNRRADAAYHLMLVIEELPEGEDMRANAERLLKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNQ5</accession>
    <name>A0A0N8GNQ5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05815</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78754.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062026.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78754">
        <property type="protein sequence ID" value="KPL78754"/>
        <property type="gene ID" value="ADN00_05815"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1639"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="80"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="216"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="258"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="296"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="333"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="366"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="392"/>
            <end position="413"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78754.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="674" mass="76339" checksum="D80465C9E9283829" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GP08</accession>
    <name>A0A0N8GP08_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glyco_trans_2-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_02545</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000011">
        <property type="protein sequence ID" value="KPL79578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061389.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000011.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02545"/>
    <dbReference type="EnsemblBacteria" id="KPL79578">
        <property type="protein sequence ID" value="KPL79578"/>
        <property type="gene ID" value="ADN00_02545"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2820"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="16"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="239" mass="27145" checksum="8925657DFA6EAD31" modified="2016-01-20" version="1">MEITTLSSDVRPTCAAIVCAYNEEKTLANLLDNLLASPYLDEIIVVNDGSTDQTAAILDHYAWKTEIQAVHLPGNHGKGYALAEGISRARSEALLFIDADLQNWHCGYELDLLRPLLQDQADMVIGYPIEGSDLFEPVDPLGLLHWISGERAVWRRDALPLVELIRDSRFGVETHINLHYRQSRQRVQFVRLNNLKHPIKLQKSSLLPALRGYAQEGAEILQTCGYWTRKMVRGWVENW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WMU3</accession>
    <name>A0A0P6WMU3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_19035</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064623.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70131">
        <property type="protein sequence ID" value="KPL70131"/>
        <property type="gene ID" value="ADN00_19035"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012427">
        <property type="entry name" value="DUF1622"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38468">
        <property type="entry name" value="PTHR38468"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07784">
        <property type="entry name" value="DUF1622"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="123" mass="14202" checksum="C8AE42CE3301B52E" modified="2016-01-20" version="1">MDQLSEVFVNISLLVDAAGVFLIIAGILTATIRYFYRLFNHHIENNNYALYRKELGRSLLLCLEFLIAADIIRTVAVEPTLQGLSTLALLILIRTFLSATVELEITGLWPWQKWQHRREIEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WPS0</accession>
    <name>A0A0P6WPS0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_18010</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000044">
        <property type="protein sequence ID" value="KPL70771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064433.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000044.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70771">
        <property type="protein sequence ID" value="KPL70771"/>
        <property type="gene ID" value="ADN00_18010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="83" mass="9457" checksum="DCFE814BE5CAD24E" modified="2016-01-20" version="1">MGISSEIIEENSERIVLKTGRCPIYKATQAVGMDNEGIEVECQANAIYYKDVMLKQWDPNLSYRLWEFRSSADAHCIEEVVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WTZ9</accession>
    <name>A0A0P6WTZ9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_14240</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000034">
        <property type="protein sequence ID" value="KPL73727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063698.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000034.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14240"/>
    <dbReference type="EnsemblBacteria" id="KPL73727">
        <property type="protein sequence ID" value="KPL73727"/>
        <property type="gene ID" value="ADN00_14240"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1368"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL73727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="128" mass="14490" checksum="3ACB0F40B938B512" modified="2016-01-20" version="1">MILLNFSHPISAEQIRQVEGLSGQPLERVLDLPTQFDNNQPFQPQLDALLAAIPLNAQEWQTAAILVNLPSLNFIAGLLLASLHGRMGYFPPILRTRPVPDSLPPRFEIAEILNLQKVRERARETRYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WU07</accession>
    <name>A0A0P6WU07_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH luxR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_14285</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000034">
        <property type="protein sequence ID" value="KPL73736.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14285"/>
    <dbReference type="EnsemblBacteria" id="KPL73736">
        <property type="protein sequence ID" value="KPL73736"/>
        <property type="gene ID" value="ADN00_14285"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019092">
        <property type="entry name" value="CRISPR-assoc_prot_NE0113/Csx12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09623">
        <property type="entry name" value="Cas_NE0113"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="213"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00421"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL73736.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="297" mass="33708" checksum="B217829B123CAA2D" modified="2016-01-20" version="1">MHQSNATLFSTLGTEPQVVTAFVDLITRQGISIDSLHILHTIGGDKRIDQATETLREEFANSSSIYKIHFHAIANLQGHPYPDIDSSESVEAFFRLLYLLIWQEKQANHIVHVCIAGGRKTMAVYGMSAAQLLFDERDRLWHLFSAGKFLESKRLHPQPGDDVRLVPIPVIPWSSLSPVLTNLSGIQDPYAALDQVAHLRLRERYDEARIFVLSLLTPAEQRVVRLLALEGLSDQEIAERLVVSPRTVEQQLRAAYAKAEEHWQVEKITRTQLIALLQYFFSTQIGENPHDKPMRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WV44</accession>
    <name>A0A0P6WV44_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Mrr_cat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_14105</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063669.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000033.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74129">
        <property type="protein sequence ID" value="KPL74129"/>
        <property type="gene ID" value="ADN00_14105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007560">
        <property type="entry name" value="Restrct_endonuc_IV_Mrr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011856">
        <property type="entry name" value="tRNA_endonuc-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04471">
        <property type="entry name" value="Mrr_cat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="domain" description="Mrr_cat" evidence="2">
        <location>
            <begin position="118"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL74129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="249" mass="27901" checksum="AB234BD9BE3B053F" modified="2016-01-20" version="1">MNAESNFPGLSAQIAVFWPLLGLAAIPLWWIGRDDRVRSLRLTFSILLGLWLLFFALRFTAWVASEPLPAFIPSWIETVLFFAAGLGLAAALLIVFSLRLQPPKPAYQRVKKAADLLALSNDGFERLVQYTYQNIGYTLEKPANPSQARLINFIATGANSPTHLVHSHRYAGRVGEPVLRELIRMLDIYPDARIDVITTSTFSPQAETYAQNKPFHLIDADELIRLFQRAQKAQLSAAAKKKTKKTARP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WVQ8</accession>
    <name>A0A0P6WVQ8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_14820</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HAD-like hydrolase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000036">
        <property type="protein sequence ID" value="KPL73065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063813.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000036.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14820"/>
    <dbReference type="EnsemblBacteria" id="KPL73065">
        <property type="protein sequence ID" value="KPL73065"/>
        <property type="gene ID" value="ADN00_14820"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1827"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006357">
        <property type="entry name" value="HAD-SF_hydro_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13344">
        <property type="entry name" value="Hydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000915">
        <property type="entry name" value="PGP-type_phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01460">
        <property type="entry name" value="HAD-SF-IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="14"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="2">
        <location>
            <position position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR000915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000915-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL73065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="264" mass="28501" checksum="57828EA7A7C2ED51" modified="2016-01-20" version="1">MPTFTPPIKGIIFDMDGVLWREDTPLADLPALFKRLDQHGIRYAFATNNATRSVEMYIQKFLTFGVQVEPQQIITSAMATAYLLKKHFPSGGPVYVAGEKGLINTLAEAGFHHNEENVLAVVAGLDRSLNYEKLSKATLLINNGAMFVGTNPDPSYPTPLGLQPGAGAMIGFISIATGVTPQYAGKPAPVMVNMALEHLKLTPQEVLVVGDRLDTDILTGQNAGCRTGLVLSGVTSRQDLETWPQAPDLVCDHVSELIATLLED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WYN7</accession>
    <name>A0A0P6WYN7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">CRISPR-associated endonuclease Cas1</fullName>
            <ecNumber evidence="8">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">cas1</name>
        <name evidence="9" type="ORF">ADN00_14225</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="8">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homodimer, forms a heterotetramer with a Cas2 homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the CRISPR-associated endonuclease Cas1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="8"/>
    <dbReference type="EMBL" id="LGCL01000034">
        <property type="protein sequence ID" value="KPL73724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063695.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000034.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14225"/>
    <dbReference type="EnsemblBacteria" id="KPL73724">
        <property type="protein sequence ID" value="KPL73724"/>
        <property type="gene ID" value="ADN00_14225"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1365"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043571">
        <property type="term" value="P:maintenance of CRISPR repeat elements"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.100.10.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01470">
        <property type="entry name" value="Cas1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002729">
        <property type="entry name" value="CRISPR-assoc_Cas1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042206">
        <property type="entry name" value="CRISPR-assoc_Cas1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042211">
        <property type="entry name" value="CRISPR-assoc_Cas1_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01867">
        <property type="entry name" value="Cas_Cas1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00287">
        <property type="entry name" value="cas1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="7 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 8" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="4 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="8" id="KW-0464">Manganese</keyword>
    <keyword evidence="2 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 8" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="8">
        <location>
            <position position="166"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01470"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL73724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="340" mass="37916" checksum="5ACDEA702980D0E3" modified="2016-01-20" version="1">MPPLYLVQQGAKIRINNRRVRVEMDPSEADGSQPELLLQVPIGQVSQVILFGNIGLTTPAIATFLESGIDVIFLTQNGEYRGQLSGGLTPHVPIRRAQYKSLADPQFSLHTAQGIVSAKLQHQRALLQRRGRELNNPEITSAAERLSESMQTVERKTSLSSLRGLEGAASAAYFSGFRRLFDPAWNFNTRQRRPPGDPVNVLLSFGYTLLAHAASGAAQAAGLDPYAGFFHEVVYNRPALGLDLMEEFRPVVDGVVLWACRSEVLTPADFTPGPPERPVVMSDDAKKRFIKAFEERMNREFLHPIRQLRLPLRQCMLEQARQIAARVVEERPGYQGMGFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZM3</accession>
    <name>A0A0P6WZM3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_15805</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72278.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72278">
        <property type="protein sequence ID" value="KPL72278"/>
        <property type="gene ID" value="ADN00_15805"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011010">
        <property type="entry name" value="DNA_brk_join_enz"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013762">
        <property type="entry name" value="Integrase-like_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002104">
        <property type="entry name" value="Integrase_catalytic"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00589">
        <property type="entry name" value="Phage_integrase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56349">
        <property type="entry name" value="SSF56349"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51898">
        <property type="entry name" value="TYR_RECOMBINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="5">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="Tyr recombinase" evidence="4">
        <location>
            <begin position="102"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL72278.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="294" mass="33383" checksum="42DC8EC0826D0C02" modified="2016-01-20" version="1">MYHLSMIEAEVLKMLALTEMSTATKQSYEFYCRDFFRWWFENNPDLDPILVSVDDVMLWLSTHPKWTSSTKHIAGSALKKFYRWKYGEHPLELLKIKRVDPGPQRTLDRGELLDVLSSIDTTTIGGIRDLAILSLMVDTGIRATEICNLEMDRLNLDKKRFTVKVKGGGIAEKLFFDYTGLCLRNWLVLRDEIVMKGVKNVFVSVGGKRPGTPLTRSGIRYLSKKMSALSGIARFSPHCLRRTFATLATENGAPSRVVQVAGGWKSIRMVERYTKALKPEAIAPFSPIDKLMND</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X023</accession>
    <name>A0A0P6X023_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">MPN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_12915</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the UPF0758 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063433.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000027.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL75537">
        <property type="protein sequence ID" value="KPL75537"/>
        <property type="gene ID" value="ADN00_12915"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1278"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08071">
        <property type="entry name" value="MPN_DUF2466"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025657">
        <property type="entry name" value="RadC_JAB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010994">
        <property type="entry name" value="RuvA_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001405">
        <property type="entry name" value="UPF0758"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30471">
        <property type="entry name" value="PTHR30471"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04002">
        <property type="entry name" value="RadC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47781">
        <property type="entry name" value="SSF47781"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00608">
        <property type="entry name" value="radc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="1" id="KW-0645">Protease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="MPN" evidence="7">
        <location>
            <begin position="115"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL75537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="239" mass="26254" checksum="87247B7A93A85102" modified="2016-01-20" version="1">MNEQQPYLLQESTPQTYTLPRLKHLPVCEQPGYRVAKDSDACSLAELLAVIIGGSTQIEIAERLLAQYGTVQKIAHAHVMEIAKVQGVGNQTALRLKASLALGRKLLQPEDERPAIHSPGDAAQILMPMLAHREQEYMIVMPLDTRNRMLDVVEIYHGSLNSSMVRIGELFKPALQRNAAGIIIAHNHPSTDPTPSPEDVSVTRAIVQAGKLLDVPVLDHLVIGLSRWVSLKEKGLGFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X167</accession>
    <name>A0A0P6X167_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_12190</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063292.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76095">
        <property type="protein sequence ID" value="KPL76095"/>
        <property type="gene ID" value="ADN00_12190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007060">
        <property type="entry name" value="FtsL/DivIC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04977">
        <property type="entry name" value="DivIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="127" mass="14677" checksum="27EE5686FF2A5A80" modified="2016-01-20" version="1">MEKRRFPIEKRQLLLGGLILLFIVLIADLNSRLMELDRLNQERNRMATRYYWVTSTEAVLKTQIAYAQSDAAVEEWAREEGHMMKEGDVVIVPMVPKDATEQPEIIPTATPQVVEEIDAWRAIFFGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X2D1</accession>
    <name>A0A0P6X2D1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CRISPR system Cms endoribonuclease Csm3</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">CRISPR type III A-associated RAMP protein Csm3</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_14265</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CRISPR-associated Csm3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000034">
        <property type="protein sequence ID" value="KPL73732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063703.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000034.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14265"/>
    <dbReference type="EnsemblBacteria" id="KPL73732">
        <property type="protein sequence ID" value="KPL73732"/>
        <property type="gene ID" value="ADN00_14265"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1373"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013412">
        <property type="entry name" value="CRISPR-assoc_RAMP_Csm3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005537">
        <property type="entry name" value="RAMP_III_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03787">
        <property type="entry name" value="RAMPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02582">
        <property type="entry name" value="cas7_TM1809"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="4" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00033183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL73732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="263" mass="28593" checksum="ED3F46754CB31BDA" modified="2016-01-20" version="1">MSDKKVQLCGRVFIEATIEAVTGLHIGGSSEGMEIGGVDNPVIRDVLTQKPYIPGSSLRGKMRSQLEKSLGLQQNNRIGQVSIHTCKTAQEYNKDGGCLVCHIFGVPGEVEATGPTLLVVRDTFLSEDSAEKLEKAHTDAAYSELKTEVAIDRVTSAASPRNIERVPAGAEFGPAELVFSIYEDADVQRLKTVLDGLLLVEDDYLGGSGSRGSGKVKFKNVKVSARGSRNYSLKKEYKTVASVQELADQFDDLQGWIRETIQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X2G4</accession>
    <name>A0A0P6X2G4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_14670</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000035">
        <property type="protein sequence ID" value="KPL73580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063781.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000035.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14670"/>
    <dbReference type="EnsemblBacteria" id="KPL73580">
        <property type="protein sequence ID" value="KPL73580"/>
        <property type="gene ID" value="ADN00_14670"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043726">
        <property type="entry name" value="DUF5668"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18917">
        <property type="entry name" value="DUF5668"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5668" evidence="2">
        <location>
            <begin position="19"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5668" evidence="2">
        <location>
            <begin position="71"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL73580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="363" mass="39216" checksum="BB789EFD38F7CB5A" modified="2016-01-20" version="1">MSNTSFESKPEHRSKRPSLFGPLLLIGLGVVLLLNTLNIVEGATWQTLLNLWPLLLIAAGLDGLWRGEGFVGSMVVMGLGAIFMLANLNILAVSPWSFIIRFWPLIIIGFGLDLIIGQRSSISALISVLIGLAIVGGMVALAFFGPVSLASSQAMQNYTFEQPLEGATSARLIIDSVGGNIFLSPGAQNQTLIEGDLALNPRENAYPHYTVQAGRGIFNLDTRNVVSVTSRFDEANWKLRVNQQVPLEIETKHSVGNQTIDLRVLNVEKIDLENVLGNALVYLPEDSVMEGSASSVIGDLSVVVPEGVDARLEVETGITSVSFPPSFIREGDFIYSSESARANPDIDLRLEQTIGSIRISLAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X321</accession>
    <name>A0A0P6X321_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_12665</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75497.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063387.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000027.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12665"/>
    <dbReference type="EnsemblBacteria" id="KPL75497">
        <property type="protein sequence ID" value="KPL75497"/>
        <property type="gene ID" value="ADN00_12665"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="8"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="263"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="40"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL75497.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="533" mass="59400" checksum="9B3D624A3A758CB9" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X3I9</accession>
    <name>A0A0P6X3I9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ATP synthase epsilon chain</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">ATP synthase F1 sector epsilon subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">F-ATPase epsilon subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 10" type="primary">atpC</name>
        <name evidence="10" type="ORF">ADN00_13860</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Produces ATP from ADP in the presence of a proton gradient across the membrane.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6 7">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the ATPase epsilon chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13860"/>
    <dbReference type="EnsemblBacteria" id="KPL74372">
        <property type="protein sequence ID" value="KPL74372"/>
        <property type="gene ID" value="ADN00_13860"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12152">
        <property type="entry name" value="F1-ATPase_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00530">
        <property type="entry name" value="ATP_synth_epsil_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001469">
        <property type="entry name" value="ATP_synth_F1_dsu/esu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020547">
        <property type="entry name" value="ATP_synth_F1_dsu/esu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020546">
        <property type="entry name" value="ATP_synth_F1_dsu/esu_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036771">
        <property type="entry name" value="ATPsynth_dsu/esu_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13822">
        <property type="entry name" value="PTHR13822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00401">
        <property type="entry name" value="ATP-synt_DE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02823">
        <property type="entry name" value="ATP-synt_DE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51344">
        <property type="entry name" value="SSF51344"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01216">
        <property type="entry name" value="ATP_synt_epsi"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6 7" id="KW-0139">CF(1)</keyword>
    <keyword evidence="6" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 6 7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ATP-synt_DE_N" evidence="9">
        <location>
            <begin position="6"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="domain" description="ATP-synt_DE" evidence="8">
        <location>
            <begin position="87"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00530"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003656"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF02823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL74372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="149" mass="16376" checksum="B52C8F658573D22F" modified="2016-01-20" version="1">MGMTIRCEIVSLENIIFEGDVDMVVLPGVHGEIGVLPNHSPFLTMLSYGIITIKQGDKENVFTVYGGVAEVQPDQVTVLAEGAESVESIDVERAEMARKRAEELLKSGIPQISEQYASMQASLLRSNLRLSAARRYRRRGQSPLSPGEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X456</accession>
    <name>A0A0P6X456_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_08125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77841.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062487.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08125"/>
    <dbReference type="EnsemblBacteria" id="KPL77841">
        <property type="protein sequence ID" value="KPL77841"/>
        <property type="gene ID" value="ADN00_08125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011055">
        <property type="entry name" value="Dup_hybrid_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016047">
        <property type="entry name" value="Peptidase_M23"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01551">
        <property type="entry name" value="Peptidase_M23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51261">
        <property type="entry name" value="SSF51261"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="SSF54106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LysM" evidence="1">
        <location>
            <begin position="94"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77841.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="520" mass="56331" checksum="CD0C4E648A4826C7" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X4M2</accession>
    <name>A0A0P6X4M2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">D-ribose transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_13565</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063561.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000031.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13565"/>
    <dbReference type="EnsemblBacteria" id="KPL74856">
        <property type="protein sequence ID" value="KPL74856"/>
        <property type="gene ID" value="ADN00_13565"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1208"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="12"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="268"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="44"/>
            <end position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL74856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="513" mass="56596" checksum="4B1C4B49248C6389" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5N5</accession>
    <name>A0A0P6X5N5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 2">Hypoxanthine phosphoribosyltransferase</fullName>
            <ecNumber evidence="1 2">2.4.2.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_07805</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>diphosphate + IMP = 5-phospho-alpha-D-ribose 1-diphosphate + hypoxanthine</text>
            <dbReference type="Rhea" id="RHEA:17973"/>
            <dbReference type="ChEBI" id="CHEBI:17368"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="EC" id="2.4.2.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Purine metabolism; IMP biosynthesis via salvage pathway; IMP from hypoxanthine: step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the purine/pyrimidine phosphoribosyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.8" evidence="1 2"/>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78363.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062429.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07805"/>
    <dbReference type="EnsemblBacteria" id="KPL78363">
        <property type="protein sequence ID" value="KPL78363"/>
        <property type="gene ID" value="ADN00_07805"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3395"/>
    <dbReference type="UniPathway" id="UPA00591">
        <property type="reaction ID" value="UER00648"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052657">
        <property type="term" value="F:guanine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004422">
        <property type="term" value="F:hypoxanthine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032264">
        <property type="term" value="P:IMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006166">
        <property type="term" value="P:purine ribonucleoside salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005904">
        <property type="entry name" value="Hxn_phspho_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01203">
        <property type="entry name" value="HGPRTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2" id="KW-0660">Purine salvage</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="3">
        <location>
            <begin position="13"/>
            <end position="159"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU364099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL78363.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="181" mass="20854" checksum="AFBE69A72FEA6AA2" modified="2016-01-20" version="1">MAGDIQSILISEKQIQQRVKELATQISEDYETLNPIIIGVLKGVLFFMSDLISHITIPIEVDFMSVSRYQAEARYKGVVRMVKDLDILVSDRHVIFVEDVIDTGLTCHYLLRLLHDRQPASLKVCAMFNKPQNRLIDIPIDYKGFDLPDRFVVGYGLDYRERYRNLPFIGLLKAEVLQRPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X637</accession>
    <name>A0A0P6X637_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_13285</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063507.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000031.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13285"/>
    <dbReference type="EnsemblBacteria" id="KPL74814">
        <property type="protein sequence ID" value="KPL74814"/>
        <property type="gene ID" value="ADN00_13285"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1240.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003759">
        <property type="entry name" value="Cbl-bd_cap"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006158">
        <property type="entry name" value="Cobalamin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036724">
        <property type="entry name" value="Cobalamin-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036594">
        <property type="entry name" value="Meth_synthase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02310">
        <property type="entry name" value="B12-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02607">
        <property type="entry name" value="B12-binding_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52242">
        <property type="entry name" value="SSF52242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51332">
        <property type="entry name" value="B12_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="1">
        <location>
            <begin position="12"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="B12-binding" evidence="2">
        <location>
            <begin position="189"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL74814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="320" mass="35787" checksum="A41982B525E7090B" modified="2016-01-20" version="1">MKDSEDSMLDPIYNIKAVARMTGLPPVTIRAWERRYGIPNPERGNQGYRLYSEEDLQVLQWLKERVDTGMSISRAVQLLTDLRAKGKDPLTAHPTIAQEQPTSLQQVRSALQAALIQFQDQRATDLLRHSLAIYPIDQVIEEVIEPVQRAIGEAWHRGEMNIASEHFVTNFFTQHLMGIISSSPPPVRPGIILAACAPNEMHQVGLLSLVVMLRWRGWDVKYLGADLSLERLDESIKTLRPWMLLFSATLPQSLNFISELPAFLQKLPHPHPLVVVGGQAFSALPDLPEGVHLVQAAGLQASTQKIESLMQANRSTPYAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7M1</accession>
    <name>A0A0P6X7M1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Flavin prenyltransferase UbiX</fullName>
            <ecNumber evidence="5">2.5.1.129</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">ubiX</name>
        <name evidence="7" type="ORF">ADN00_03830</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Flavin prenyltransferase that catalyzes the synthesis of the prenylated FMN cofactor (prenyl-FMN) for 4-hydroxy-3-polyprenylbenzoic acid decarboxylase UbiD. The prenyltransferase is metal-independent and links a dimethylallyl moiety from dimethylallyl monophosphate (DMAP) to the flavin N5 and C6 atoms of FMN.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>dimethylallyl phosphate + FMNH2 = phosphate + prenyl-FMNH2</text>
            <dbReference type="Rhea" id="RHEA:37743"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57618"/>
            <dbReference type="ChEBI" id="CHEBI:87467"/>
            <dbReference type="ChEBI" id="CHEBI:88052"/>
            <dbReference type="EC" id="2.5.1.129"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the UbiX/PAD1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.129" evidence="5"/>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061642.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03830"/>
    <dbReference type="EnsemblBacteria" id="KPL79030">
        <property type="protein sequence ID" value="KPL79030"/>
        <property type="gene ID" value="ADN00_03830"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.120"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106141">
        <property type="term" value="F:flavin prenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01984">
        <property type="entry name" value="ubiX_pad"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036551">
        <property type="entry name" value="Flavin_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003382">
        <property type="entry name" value="Flavoprotein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004507">
        <property type="entry name" value="UbiX-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43374">
        <property type="entry name" value="PTHR43374"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02441">
        <property type="entry name" value="Flavoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52507">
        <property type="entry name" value="SSF52507"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00421">
        <property type="entry name" value="ubiX_pad"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 5" id="KW-0288">FMN</keyword>
    <keyword evidence="7" id="KW-0456">Lyase</keyword>
    <keyword evidence="1 5" id="KW-0637">Prenyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Flavoprotein" evidence="6">
        <location>
            <begin position="6"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="14"/>
            <end position="16"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="91"/>
            <end position="94"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="126"/>
        </location>
        <ligand>
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="156"/>
        </location>
        <ligand>
            <name>dimethylallyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:88052"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>dimethylallyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:88052"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022602"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL79030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="190" mass="20264" checksum="C127E0B837778222" modified="2016-01-20" version="1">MNEKDKRLIIAITGASGAVYGIRALQILRAARVETHLVISAAAALTIPQETSWSVAQVLELADFTYSDSDTGARIASGSFSANGMLIAPCSIKTLSAVANSACDTLIARAADVCLKEGRPLLLAVRETPLHRGHLRLMDLAARSGAVIFPPVPAFYGHPQTLQDVIDASVGRMLARLGIENELYPRWTGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X8D1</accession>
    <name>A0A0P6X8D1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex</fullName>
            <ecNumber evidence="5">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_11335</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + acetyl-CoA = (R)-N(6)-(S(8)-acetyldihydrolipoyl)-L-lysyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:17017"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:10478"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="ChEBI" id="CHEBI:83111"/>
            <dbReference type="EC" id="2.3.1.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 5">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="5"/>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76548.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063127.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11335"/>
    <dbReference type="EnsemblBacteria" id="KPL76548">
        <property type="protein sequence ID" value="KPL76548"/>
        <property type="gene ID" value="ADN00_11335"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.966"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045254">
        <property type="term" value="C:pyruvate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006086">
        <property type="term" value="P:acetyl-CoA biosynthetic process from pyruvate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045257">
        <property type="entry name" value="E2/Pdx1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23151">
        <property type="entry name" value="PTHR23151"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="SSF47005"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4 5" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="6">
        <location>
            <begin position="2"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="7">
        <location>
            <begin position="108"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="7">
        <location>
            <begin position="156"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL76548.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="437" mass="45966" checksum="215800731980F91B" modified="2016-01-20" version="1">MAKEVIMPKFGFTQEDSQILAWLKNEGDPVEKGDPIAEVSTDKVSMEIEAPEDGILSGILYPVGAVVPVTQVVAYILQPGENLPAAASAPVGKPAPAAVVQKEEKLSGASPVAARMAKEAGVDLSGVEGSGPGGRILKQDVEFLLSHPQASAGKVNATPAARSLAAQAKLELNQVSGSGPEGRIQAADVRRASQAGPAATAPAVPAAARRTIPFTGMRRAIGLNLQASYQQIPHITLQVDVDMSASEALRVQANQMLPAGSKDKVSLTAVIARAVVWSLARNPILNSRLEEEEIVLLPDVNLGIAVALDEGLLVPVIQQAQGKGTLQLAAELREVTERARGGKLRQTDLQDGTFTISNLGMFGIDRFAAIINPPQTAILAVGQVRKQFVPDEHGQPVLHSVMTATLSADHRVIDGADAARFLADLRQALEKPEVMTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9T8</accession>
    <name>A0A0P6X9T8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_11020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063065.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76496">
        <property type="protein sequence ID" value="KPL76496"/>
        <property type="gene ID" value="ADN00_11020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132942" evidence="2">
        <location>
            <begin position="27"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="30"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL76496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="197" mass="21614" checksum="4BD0110F79827C98" modified="2016-01-20" version="1">MKKWIGIALAASLFLAGFAVVSPVYAQSGSTETGMPGGPWGGPGRGPGGMGQPEDAPEWGLMEDYLLQYLADTYGLDVEAAKARIDEGDMLSEILLDAGVEDVPQAMMDAREYAFEQMEAEGYGPAWSDDEDGLFGRMMDGMRGRFAGLTDEDRGNFPRGNWEDGEQPYYNYDEENCPMWDADDIPQAERQGRGGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9V3</accession>
    <name>A0A0P6X9V3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SBP_bac_5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_06355</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062122.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78835">
        <property type="protein sequence ID" value="KPL78835"/>
        <property type="gene ID" value="ADN00_06355"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1774"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002741">
        <property type="entry name" value="MppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132953" description="SBP_bac_5 domain-containing protein" evidence="2">
        <location>
            <begin position="21"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="domain" description="SBP_bac_5" evidence="3">
        <location>
            <begin position="113"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL78835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="586" mass="65154" checksum="F0ACD6C89E545807" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XA81</accession>
    <name>A0A0P6XA81_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 8 10">Thymidine kinase</fullName>
            <ecNumber evidence="2 8 10">2.7.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">tdk</name>
        <name evidence="12" type="ORF">ADN00_03560</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8 10">
            <text>ATP + thymidine = ADP + dTMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19129"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17748"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:63528"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.21"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="8">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8 11">Belongs to the thymidine kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.21" evidence="2 8 10"/>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061590.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03560"/>
    <dbReference type="EnsemblBacteria" id="KPL78981">
        <property type="protein sequence ID" value="KPL78981"/>
        <property type="gene ID" value="ADN00_03560"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.63"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004797">
        <property type="term" value="F:thymidine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071897">
        <property type="term" value="P:DNA biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00124">
        <property type="entry name" value="Thymidine_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001267">
        <property type="entry name" value="Thymidine_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020633">
        <property type="entry name" value="Thymidine_kinase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11441">
        <property type="entry name" value="PTHR11441"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00265">
        <property type="entry name" value="TK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF035805">
        <property type="entry name" value="TK_cell"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00603">
        <property type="entry name" value="TK_CELLULAR_TYPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 8 10" id="KW-0237">DNA synthesis</keyword>
    <keyword evidence="6 8 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 8 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="active site" description="Proton acceptor" evidence="8 9">
        <location>
            <position position="87"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="13"/>
            <end position="20"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="86"/>
            <end position="89"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR035805-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU004165"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KPL78981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="190" mass="20944" checksum="4556FB019151AC7D" modified="2016-01-20" version="1">MKHETGSLEVICGSMFCGKTEELIRRLRRAVIARQKVQVFKPAIDRRYAEEKVASHAGMVFDAIPVGHSSEVLAHLLPETTVVGVDEAQFFDEGIVDVVSQLADQGVRVIAAGLDLDFRGEPFGCMPVLMAKAERVDKLHAICMVCGESATRTQRLVNGEPARYDDPVVIVGASEMYEARCRLHHIVPRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XA95</accession>
    <name>A0A0P6XA95_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_16535</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064148.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72079">
        <property type="protein sequence ID" value="KPL72079"/>
        <property type="gene ID" value="ADN00_16535"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="372" mass="40939" checksum="6CF84FA71A77EB5E" modified="2016-01-20" version="1">MKNRSSRSLSHLACITLLLLMLAGSFLAGIVFQKSGGLSKLRLALAFTSASQPVAAPTEAPEPTQQPDQESIRQALTINPNRVSLNQVDLMSRPAGEYAFLAAGHVYGRPGEEHPHPASTFVEMVPTINAMDLDMLFLLGDTVPNPSMVYLEQLESSVLDRLEMPVYNAVGNHDVRDRAFYEQRYGPTYYTFQHGPAAFIILDTEIDPGKITESQKAFFEQAIEAALSDPQVKFFFVMMHKVLFIPAETITALFESGVAAAAPNAKENYGDPNFDSILNETLVPAARQKPVYLVAGDVGAWGGNFSPYYQKHPDVDLTMLAAGFGDTEQDAALWVRYNSEQVEIGFIHPNGQPVVDYSEKDLNYYLAKLPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XB48</accession>
    <name>A0A0P6XB48_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Histidine kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_10285</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062914.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10285"/>
    <dbReference type="EnsemblBacteria" id="KPL76963">
        <property type="protein sequence ID" value="KPL76963"/>
        <property type="gene ID" value="ADN00_10285"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2521"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04623">
        <property type="entry name" value="CBS_pair_bac_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044725">
        <property type="entry name" value="CBSX3_CBS_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0129">CBS domain</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="10"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="2">
        <location>
            <begin position="77"/>
            <end position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL76963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="144" mass="16291" checksum="F7B151B21E5DF8BC" modified="2016-01-20" version="1">MLNTIRHILQVKGWDTWFVRPDSSVFEALKQMADREIGALLVMEGDHLVGIFSERDYARKVILKGKASKDTPVAEIMTSTVFTIHPDQTVQEAMELMTEKHVRHLPVVEGDKVIGMVSIGDVVRSIIYQQKKIISEMENKIISG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBE6</accession>
    <name>A0A0P6XBE6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">M20_dimer domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_01975</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000007">
        <property type="protein sequence ID" value="KPL80063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061286.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000007.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01975"/>
    <dbReference type="EnsemblBacteria" id="KPL80063">
        <property type="protein sequence ID" value="KPL80063"/>
        <property type="gene ID" value="ADN00_01975"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00758">
        <property type="entry name" value="ARGE_DAPE_CPG2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="2">
        <location>
            <begin position="237"/>
            <end position="380"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL80063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="490" mass="54176" checksum="5B741D78EBE421DA" modified="2016-01-20" version="1">MLFQILLPVLVVLLFAAAFILIRTATFSTAGHPAEPAKPIPLEPRQAAMHLAQAIRCETVSTARGKPNRQALLDMHRFLELSYPLVHQRLERTQIAEYSLVYRWPGAQPELDPILLMAHLDVVPVDPATLPAWTYPPFDGAIEDGFVWGRGALDMKNQLVAIFEAVEHLLAAGYQPSRDVYISCGHDEEIGGIDGSRQVAAWFREQGTRFSLVLDEGPAIVLDGYPGIQSPVALVATGEKGYMTLELSVECEPGHSSIPPRQTAIGILSRAITRLEAHPMPAHIRALQPFYRAVGSAAPFSMQLSFANLWLFGAYCRGMMETNPQTNAAMRTTTAPTIISGGIKDNILPRQASARINFRILPGDTISSVCEHVRKVINDPRVKFQPYHGIAWEPSPVADINSPAFISIRHLIQQTFGSLPVAPFIMLGATDSRHFNDLAGQIFRFSPMRLTAEDQARIHGINERVAVDELAKMVQFFIQLVQAWSQPKIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-08-12" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBL0</accession>
    <name>A0A0P6XBL0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ABC transmembrane type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_16010</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72110">
        <property type="protein sequence ID" value="KPL72110"/>
        <property type="gene ID" value="ADN00_16010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3636"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="59"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="92"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="120"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="178"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="223"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="57"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL72110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="261" mass="27945" checksum="D9D0A60463DDF721" modified="2016-01-20" version="1">MIITFIVVITAIFAPLIAPYDPLKITLADRLQPPSEKYWLGTDHLGRDVFSRVVYGARISLQVGIVSVFLGTIVGLIAGAAAGYIGNGVDTVIMSIMDAIYAFPAILLALALVAAFEPGLVTVMTAIAIVRIPIFARTVRSSVLAEREKEYIEAARCIGLNGFGILTRHILPNITAPLIVVTTTYFAAAIVVEASLSFLGLGVPPPQASWGVMLNDGRKYMEAMPHVVLYPGIAISLTVLGFNLLGDGLRDVLDPRLRNIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XC20</accession>
    <name>A0A0P6XC20_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cell division topological specificity factor</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">minE</name>
        <name evidence="4" type="ORF">ADN00_02255</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 3">Prevents the cell division inhibition by proteins MinC and MinD at internal division sites while permitting inhibition at polar sites. This ensures cell division at the proper site by restricting the formation of a division septum at the midpoint of the long axis of the cell.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the MinE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000009">
        <property type="protein sequence ID" value="KPL79804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061337.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000009.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02255"/>
    <dbReference type="EnsemblBacteria" id="KPL79804">
        <property type="protein sequence ID" value="KPL79804"/>
        <property type="gene ID" value="ADN00_02255"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2773"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007049">
        <property type="term" value="P:cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032955">
        <property type="term" value="P:regulation of division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1070.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00262">
        <property type="entry name" value="MinE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005527">
        <property type="entry name" value="MinE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036707">
        <property type="entry name" value="MinE_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03776">
        <property type="entry name" value="MinE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55229">
        <property type="entry name" value="SSF55229"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01215">
        <property type="entry name" value="minE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="3" id="KW-0132">Cell division</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00025265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL79804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="87" mass="9726" checksum="84446478F32BEDF3" modified="2016-01-20" version="1">MANWLDKLLSEKPKSASQAKERLKLVLIHDRTSLSPKAVEALKNELLAVISRYVDIDPSAVNIAVAQDGREERLVADIPLNPSPRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XCD6</accession>
    <name>A0A0P6XCD6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Galactosyldiacylglycerol synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_01865</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000007">
        <property type="protein sequence ID" value="KPL80041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061264.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000007.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01865"/>
    <dbReference type="EnsemblBacteria" id="KPL80041">
        <property type="protein sequence ID" value="KPL80041"/>
        <property type="gene ID" value="ADN00_01865"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2299"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009247">
        <property type="term" value="P:glycolipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009695">
        <property type="entry name" value="Diacylglyc_glucosyltr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007235">
        <property type="entry name" value="Glyco_trans_28_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04101">
        <property type="entry name" value="Glyco_tran_28_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06925">
        <property type="entry name" value="MGDG_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MGDG_synth" evidence="6">
        <location>
            <begin position="22"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_tran_28_C" evidence="5">
        <location>
            <begin position="213"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF04101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL80041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="382" mass="42277" checksum="FE174110BF5670F7" modified="2016-01-20" version="1">MIHLQPDQPRIVFLFSDTGGGHRSASEAIIEAIQLEYPNQFTTEMVDIFLQYAPSPFNLAPRVYPPLSRMPDVWKFGYQISDGPRRANMVYNAIWPYVRRSIHRLIHENPCDLIVSVHPLINAPVLRALRKETVPYITVVTDMVSTHAAWYNPNADLVIVPTEAAKERAVKVGVAVEKVQVVGLPVADRFCQPVGDKLALREQLGWPQDRPVVLLVGGGEGMGPLEQVARAIEKRSPNAALVVITGRNRKLKATLEAHKWSIPTFVYGFVRDMPDFMRAADILVSKAGPGTICEAFIAGLPIILYSKMPGQEDGNVTYVVQQGAGIWAPEPNQVADAVCRWIESPEEREKAAQNCLRVARPDAARQIARILASAARKKQQGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XCE6</accession>
    <name>A0A0P6XCE6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_01660</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01660"/>
    <dbReference type="EnsemblBacteria" id="KPL80575">
        <property type="protein sequence ID" value="KPL80575"/>
        <property type="gene ID" value="ADN00_01660"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000801">
        <property type="entry name" value="Esterase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00756">
        <property type="entry name" value="Esterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132978" evidence="2">
        <location>
            <begin position="36"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL80575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="317" mass="34954" checksum="A3F97269F3258B73" modified="2016-01-20" version="1">MRQTSRKPFTRRNIALFLVSLAAVSLLSACRPPFAPRVIFARPAVLTQTASATLPVDTATPVPPTATPSPIPATPTPVGCQEPNGRVETRVFETELFPKPITVNLYLPPCYDPTAETPYPLVILLHGQSYTHEQWLDLNLPQAADHLITSKQAAPFIVAMPREEYYLQDYLDSKYGSALIQGLLPWLSAEANACGEARCRAIGGISRGAGWAALLAFENPGTVSAVGAHSIPNPPFSDYRLFYLLGLTPEGQVPRVYVDTGTSDRYFSGAQRFVRLLEEYEIDHLWLQADGAHNNEYWAAHMPEYMAWYAAQIAPPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XCG0</accession>
    <name>A0A0P6XCG0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 8">Methionyl-tRNA formyltransferase</fullName>
            <ecNumber evidence="4 8">2.1.2.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">fmt</name>
        <name evidence="11" type="ORF">ADN00_08500</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 8">Attaches a formyl group to the free amino group of methionyl-tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 8">
            <text>(6S)-10-formyltetrahydrofolate + L-methionyl-tRNA(fMet) = (6S)-5,6,7,8-tetrahydrofolate + H(+) + N-formyl-L-methionyl-tRNA(fMet)</text>
            <dbReference type="Rhea" id="RHEA:24380"/>
            <dbReference type="Rhea" id="RHEA-COMP:9952"/>
            <dbReference type="Rhea" id="RHEA-COMP:9953"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:57454"/>
            <dbReference type="ChEBI" id="CHEBI:78530"/>
            <dbReference type="ChEBI" id="CHEBI:78844"/>
            <dbReference type="EC" id="2.1.2.9"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3 8">Belongs to the Fmt family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.9" evidence="4 8"/>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062576.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08500"/>
    <dbReference type="EnsemblBacteria" id="KPL77919">
        <property type="protein sequence ID" value="KPL77919"/>
        <property type="gene ID" value="ADN00_08500"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.703"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004479">
        <property type="term" value="F:methionyl-tRNA formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd08646">
        <property type="entry name" value="FMT_core_Met-tRNA-FMT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08704">
        <property type="entry name" value="Met_tRNA_FMT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00182">
        <property type="entry name" value="Formyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005794">
        <property type="entry name" value="Fmt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005793">
        <property type="entry name" value="Formyl_trans_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002376">
        <property type="entry name" value="Formyl_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036477">
        <property type="entry name" value="Formyl_transf_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011034">
        <property type="entry name" value="Formyl_transferase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001555">
        <property type="entry name" value="GART_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044135">
        <property type="entry name" value="Met-tRNA-FMT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041711">
        <property type="entry name" value="Met-tRNA-FMT_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02911">
        <property type="entry name" value="Formyl_trans_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00551">
        <property type="entry name" value="Formyl_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50486">
        <property type="entry name" value="SSF50486"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53328">
        <property type="entry name" value="SSF53328"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00460">
        <property type="entry name" value="fmt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00373">
        <property type="entry name" value="GART"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Formyl_trans_N" evidence="9">
        <location>
            <begin position="4"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="Formyl_trans_C" evidence="10">
        <location>
            <begin position="205"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Tetrahydrofolate (THF) binding" evidence="8">
        <location>
            <begin position="110"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00016014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL77919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="304" mass="32811" checksum="B02B14397B736180" modified="2016-01-20" version="1">MAKRIVFMGSPDFSLPSLQYLAQNYPVVGVITQPDRPAGRGRALTPPPVKVLAQELGLPVFQPEKLRAPEAFEVLVSWKPDLIVVTAYGQILRRQVLDLPEYGCVNVHASLLPRWRGAAPIQAAILHGDEKTGVTIMKMDAGVDTGPMLAKWETTIGAEETAGSLSDRLAEQGGRLLVEVLPDYLSGKLTPHPQPQDGATYAPILSKEEGRLDFSQPAVALERKVRAFSPWPGAYMEWTGGLMKVHKASVSLAAGSSPELRAVLDGYPAVGTADGWLVLEEIQPAGKKAMQGKAYLAGTRNWVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDH8</accession>
    <name>A0A0P6XDH8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pyridoxal 5'-phosphate synthase subunit PdxT</fullName>
            <ecNumber evidence="4">4.3.3.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Pdx2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Pyridoxal 5'-phosphate synthase glutaminase subunit</fullName>
            <ecNumber evidence="4">3.5.1.2</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">pdxT</name>
        <name evidence="7" type="ORF">ADN00_07480</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 4">
            <text>H2O + L-glutamine = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="3.5.1.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>aldehydo-D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + L-glutamine = H(+) + 3 H2O + L-glutamate + phosphate + pyridoxal 5'-phosphate</text>
            <dbReference type="Rhea" id="RHEA:31507"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
            <dbReference type="EC" id="4.3.3.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4">Cofactor biosynthesis; pyridoxal 5'-phosphate biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">In the presence of PdxS, forms a dodecamer of heterodimers. Only shows activity in the heterodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the glutaminase PdxT/SNO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.3.6" evidence="4"/>
    <dbReference type="EC" id="3.5.1.2" evidence="4"/>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062358.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07480"/>
    <dbReference type="EnsemblBacteria" id="KPL78294">
        <property type="protein sequence ID" value="KPL78294"/>
        <property type="gene ID" value="ADN00_07480"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3321"/>
    <dbReference type="UniPathway" id="UPA00245"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004359">
        <property type="term" value="F:glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036381">
        <property type="term" value="F:pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006543">
        <property type="term" value="P:glutamine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042823">
        <property type="term" value="P:pyridoxal phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01749">
        <property type="entry name" value="GATase1_PB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01615">
        <property type="entry name" value="PdxT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002161">
        <property type="entry name" value="PdxT/SNO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021196">
        <property type="entry name" value="PdxT/SNO_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31559">
        <property type="entry name" value="PTHR31559"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01174">
        <property type="entry name" value="SNO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005639">
        <property type="entry name" value="Glut_amidoT_SNO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03800">
        <property type="entry name" value="PLP_synth_Pdx2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01236">
        <property type="entry name" value="PDXT_SNO_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51130">
        <property type="entry name" value="PDXT_SNO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 7" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="L-glutamine binding" evidence="4 6">
        <location>
            <begin position="46"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="L-glutamine binding" evidence="4 6">
        <location>
            <begin position="139"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4 5">
        <location>
            <position position="77"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="4 5">
        <location>
            <position position="176"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="4 5">
        <location>
            <position position="178"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 6">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008345"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01615"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR005639-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR005639-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL78294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="194" mass="21019" checksum="8D1CF44D9339833D" modified="2016-01-20" version="1">MKIGILALQGAFIEHQAILDRLGVDTSQVRLPQHLAGLDGLIIPGGESTTIGKLMVAFRLLEPLREFGREKAIWGTCAGAILLSKDAGRDQPLLGLMDITIQRNAFGRQVESFEAALDVPALKPFNSNGSNPPYQAVFIRAPLIAAAGPGVEVCASLPDSRIVAARQGKLLATSFHPELTEDDRFHRWFLELAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDN4</accession>
    <name>A0A0P6XDN4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FCD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_00795</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00795"/>
    <dbReference type="EnsemblBacteria" id="KPL81096">
        <property type="protein sequence ID" value="KPL81096"/>
        <property type="gene ID" value="ADN00_00795"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07729">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="FCD" evidence="4">
        <location>
            <begin position="57"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00895"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL81096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="195" mass="22853" checksum="AFB45E6A72B735E1" modified="2016-01-20" version="1">MGVSTASVREQLEVARALKLVEVKPRTGIKPLPYNFSDAIHISLNYAIEVNPELFRDFSDLRKKIEAAYWYEVAAQVTGEDIHYLNQLVDRAMEKLRSRPPQIPQWEHRELHITLYKRLRNPFVLGLLEAYWDMYEQAGLNSFVDLAYLEAVWQYHQSIVSALEKGDLVGGYKMLTEHMNLLYQRPHDDSRQKFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDX3</accession>
    <name>A0A0P6XDX3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_06715</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000018">
        <property type="protein sequence ID" value="KPL78413.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062211.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000018.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06715"/>
    <dbReference type="EnsemblBacteria" id="KPL78413">
        <property type="protein sequence ID" value="KPL78413"/>
        <property type="gene ID" value="ADN00_06715"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006824">
        <property type="term" value="P:cobalt ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003339">
        <property type="entry name" value="ABC/ECF_trnsptr_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012809">
        <property type="entry name" value="ECF_CbiQ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02361">
        <property type="entry name" value="CbiQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02454">
        <property type="entry name" value="ECF_T_CbiQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="44"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="247"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL78413.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="267" mass="28892" checksum="0543E72238144194" modified="2016-01-20" version="1">MSASVFAPPQPFSSPLHRLDARVKLALALAYILTTALAPQGAWAVYVLLLALITAAAVLSELGVGWVYRRSLIAVPFALAAMPLVFSLPGPAWFSLRLGSLSLTASLTGAERAASILLKVWLSVQAGILLSATTRQTALLAAMRALKLPRLLVAVMGLMWRYLDLMLAEARRLLRARASRSARSAQPGLRTGGTLAWRAKVTGGMAGSLMLRSLERSERVYQAMLARGYDGEAREAQHHPLAAADRWLLVGGLWVFLMVNLLALLWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XEK6</accession>
    <name>A0A0P6XEK6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_14710</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000035">
        <property type="protein sequence ID" value="KPL73588.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063789.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000035.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL73588">
        <property type="protein sequence ID" value="KPL73588"/>
        <property type="gene ID" value="ADN00_14710"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="SSF54106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="SSF55797"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133011" description="LysM domain-containing protein" evidence="3">
        <location>
            <begin position="34"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="328"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="4">
        <location>
            <begin position="217"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL73588.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="355" mass="37121" checksum="2EE6A717076943FC" modified="2016-01-20" version="1">MSISRFHGFQLLWFSSLLAVLVSLGFTARPARAQDENPPLPNAYDLIASVNALRNLHGLGSLNMDGSLMAAAQQQADDLAAGLAFGHTGAGGTSADDRARLNGYPFYEGIDVMECWASVPPGTGTGDVVFGFWSDEVHTNVMIHAYARDVGAGIAADENGAIFLVLDVGADYWGTSLRGRATATTLPGWMITPGGPTLTPEVIFPVFTATPQPDGSLKHHVEPGQALWTIAIAYEMKIDEIARLNGLDAQNPIIYAGQDLLLRQPGAAPPTAPAPLASAPTVDGSPPAAVTRAANLAAPTRTTSPSPEITLTATPAPARALPPSNRRVTGLLLLIFCAGGLLALGWSWFKPRAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XF79</accession>
    <name>A0A0P6XF79_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Sodium ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_07580</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062375.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07580"/>
    <dbReference type="EnsemblBacteria" id="KPL78307">
        <property type="protein sequence ID" value="KPL78307"/>
        <property type="gene ID" value="ADN00_07580"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3343"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025302">
        <property type="entry name" value="DUF4162"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13732">
        <property type="entry name" value="DUF4162"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="4"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL78307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="301" mass="33220" checksum="99CB82CF183997A1" modified="2016-01-20" version="1">MVSVVVEQITKTFGQQRAVDGVSFAVEPGEIFGLLGPNGAGKTTSIRIILDIFKPDSGSVSVLGGPMSEAKKNRIGYLPEERGLYQEIPLERCLNYLVSLKGLSPAAAQERIEPLMERFDLTEHRKKKVKELSKGMQQKAQLIVTLAHKPELIIIDEPFSALDPVNTQMVKDLLMEEREKGTCIVMCTHQMHQVEELCDRMVLINRGKSMLYGSVNEIRRQFAEQDLLVRALNPIPDTIPGVVKVEGHNGLTRLVLADGVSPQSVLKALLEMGVALEHFEVATPTLDEIFIQVVKGEGAQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XFV1</accession>
    <name>A0A0P6XFV1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_04055</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061681.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04055"/>
    <dbReference type="EnsemblBacteria" id="KPL79062">
        <property type="protein sequence ID" value="KPL79062"/>
        <property type="gene ID" value="ADN00_04055"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="279"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="324"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="369"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="21"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="309"/>
            <end position="401"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL79062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="408" mass="43563" checksum="9F98AB2683BBD544" modified="2016-01-20" version="1">MSITQAFLEALESLNANKMRSALTILGIVIGVAAVIAMLAVGQGAQDTITGSISGIGSNLLFVFSGNFQEEVRNVQELTLDDAEALSDVFQAPHVQSVAPVINSDLEITFAGESTRAEVNGVTPVFAEVRNYTISEGEFINQDHLLGQASVALIGVEVADNLFDRREAITGETIRIEGQPFRVIGVLEPKGGSSFGSQDNVVLVPFTTAQSRLIRRSRERVDVIYVQATSADTVKLATDEIAQILRSRHRIFLGPDDFTIFSQQDFVETAETITGVFTIFLGGVAGISLLVGGIGIMNIMLVSVTERTREIGLRKALGARKADILIQFLTESSLLSLFGGLIGIGLGWLLSFTVGQIAAANDTPINPAIGLNAVLLATLFSTAVGLFFGIYPANRAANLEPVEALRHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XG05</accession>
    <name>A0A0P6XG05_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_04450</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061750.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04450"/>
    <dbReference type="EnsemblBacteria" id="KPL79117">
        <property type="protein sequence ID" value="KPL79117"/>
        <property type="gene ID" value="ADN00_04450"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1060.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009051">
        <property type="entry name" value="Helical_ferredxn"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17179">
        <property type="entry name" value="Fer4_22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="220"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="296"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL79117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="334" mass="37894" checksum="E12CD6FA680C0A10" modified="2016-01-20" version="1">MNVQIAKKDLPALLQQWAQSAQVLAPVKKENFTAFEVIADVSEMDLEQAHNTRYPLKSLFLPQSEVLFRYQNGEYVPAVPQKGPRVIFGARPCDARALTLLDTVFEEEGSQDPYWKARREASTLVGMGCDQPCESCFCTTVGSGPFDRSGLDVLVTPVDGVYALEALTEKGQKLVQSLQPLPAETQKRVEEVQSRAAAEMKPAFEVKSIRDKLYGLFESEYWQQVQQSCLGCGVCTYLCPTCFCFDIVDETQRGERVRNWDTCMFSVYSLEASGHNPRPSRRERTRQRLMHKYAYWLDHIDQIGCTGCGRCVRYCPVGLDIRDMIRRAQAWEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGE8</accession>
    <name>A0A0P6XGE8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_06070</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062074.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06070"/>
    <dbReference type="EnsemblBacteria" id="KPL78791">
        <property type="protein sequence ID" value="KPL78791"/>
        <property type="gene ID" value="ADN00_06070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016116">
        <property type="term" value="P:carotenoid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045892">
        <property type="entry name" value="CrtISO-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46313">
        <property type="entry name" value="PTHR46313"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0934">Plastid</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="495" mass="55832" checksum="8AACB53F26556ABC" modified="2016-01-20" version="1">MAQQPVLVIIGAGIGGLAAGVYAQMSGFETHIFEQHTIPGGFCTSWKRKGYLFDGCIHDLAGAGSNSPLNHLWQELCPDRLENIHYHDVITQVEDSHGHHLTVYANIDRFEAHLKSIAPEDAGVIKEYCAAARYFLAHDFYALQEATPADFLQWFPHLPFLFRWGRQSLEQVARKFKNPFLREAFPKIQYNFAGCPALVQMGFLAAQHKKEMGWPAGGSLAFAQSIARRFTRLGGQLHYHSRVRKVLVENDQACGVELEDGQQQRADWVISAGDGHTTIFKLLEGKYTNKFLRHYYTCAPDENSMNLQVSLGINRNLSGLPRAIFYHLEQPVSIAGHEVKDLEIEIYNYDPSIAPQGKSVIRLLSTSPYSYWNALGYGSEAYQQEKQKVADAFIDLLLQRFPDIRQDIEVVDVATPITSERYTASYHGLQAWYPEGQFGRILMKGISPNLPGLKRFSMTGQWSNGMMGINSVAITSRNLIRSLCKKFKMRFETTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGF5</accession>
    <name>A0A0P6XGF5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79217.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061872.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05090"/>
    <dbReference type="EnsemblBacteria" id="KPL79217">
        <property type="protein sequence ID" value="KPL79217"/>
        <property type="gene ID" value="ADN00_05090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amino_oxidase" evidence="1">
        <location>
            <begin position="11"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79217.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="436" mass="49321" checksum="92E28BAA145488C9" modified="2016-01-20" version="1">MKIAVIGAGVGGMSAAYDLAKAGHQVTIFEAADHTGGLAAGFKQPHWNWSVEKFYHHWFQTDSSMLGLIAELGLSDKVMFPRPVTVMYHEGRFYPFDSILAALLYPGLGWGLGKIRFGLVGLYLRLTKNWRALEKTTVDAWMRKWAGDRVYEQMWEPMMVGKFGEKYAKQVNMAWMWARLHARTTRLGTFQGGFQAFCDQFADILRGMGVEIQLSTAVMNLSAAPEGKVSLQLTSESLVFDQVLNTTSPALMARMAPDLPPDYLKGLLNLRSMGAVVMVLSLRQQLSEQGYYWFNLPKSAGFPFLALVEHTNFLPTEHYGGDHILYCGDYLETDHEYFQLSKEELLQRFLPSFQRINPNFKPDWVKESWLFRTHYAQPIPLVNHSANIPSIRTPITGLYFASMSQVYPWDRGTNFAVKIGREAAQMMLKDSQAPAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGH5</accession>
    <name>A0A0P6XGH5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ATP synthase gamma chain</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">ATP synthase F1 sector gamma subunit</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">F-ATPase gamma subunit</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">atpG</name>
        <name evidence="10" type="ORF">ADN00_13870</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 9">Produces ATP from ADP in the presence of a proton gradient across the membrane. The gamma chain is believed to be important in regulating ATPase activity and the flow of protons through the CF(0) complex.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">F-type ATPases have 2 components, CF(1) - the catalytic core - and CF(0) - the membrane proton channel. CF(1) has five subunits: alpha(3), beta(3), gamma(1), delta(1), epsilon(1). CF(0) has three main subunits: a, b and c.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cell membrane</location>
            <topology evidence="9">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the ATPase gamma chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063619.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000032.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13870"/>
    <dbReference type="EnsemblBacteria" id="KPL74374">
        <property type="protein sequence ID" value="KPL74374"/>
        <property type="gene ID" value="ADN00_13870"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1351"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045261">
        <property type="term" value="C:proton-transporting ATP synthase complex, catalytic core F(1)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046933">
        <property type="term" value="F:proton-transporting ATP synthase activity, rotational mechanism"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042777">
        <property type="term" value="P:proton motive force-driven plasma membrane ATP synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12151">
        <property type="entry name" value="F1-ATPase_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00815">
        <property type="entry name" value="ATP_synth_gamma_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035968">
        <property type="entry name" value="ATP_synth_F1_ATPase_gsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000131">
        <property type="entry name" value="ATP_synth_F1_gsu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11693">
        <property type="entry name" value="PTHR11693"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00231">
        <property type="entry name" value="ATP-synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00126">
        <property type="entry name" value="ATPASEGAMMA"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52943">
        <property type="entry name" value="SSF52943"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01146">
        <property type="entry name" value="ATPsyn_F1gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0066">ATP synthesis</keyword>
    <keyword evidence="9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 9" id="KW-0139">CF(1)</keyword>
    <keyword evidence="4 9" id="KW-0375">Hydrogen ion transport</keyword>
    <keyword evidence="5 9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023196"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL74374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="299" mass="34451" checksum="0D0CDF2A149261DA" modified="2016-01-20" version="1">MNSTRDLRRRIRSVKNISQVTRALETVSARKVRQAMNLVQRSHPYTEKAWKVLLHLAREPERKNLHPLLTIRSKVEKILVVMISSDRGLAGAYNVNVVRQTLEHFRDVEQEVSYVPVGRKGRDMLLRRGMRILAEFSNLPTPPKFSDVSAIGFLLVDTYLQGEVDKIYLCYTEFESMVKQRVVIRDLLPVVLEYEKPPEKRSFNITHTSKAVFEYEPDRDTILDMIVPRFIALQVFEAILSSQASEHAARRMAMNNATNNAKDIIDSLQLDYNKMRQKTITDDIIEIASGAESLTQNTY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGI4</accession>
    <name>A0A0P6XGI4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Thioredoxin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_13705</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the thioredoxin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74383.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063627.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000032.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13705"/>
    <dbReference type="EnsemblBacteria" id="KPL74383">
        <property type="protein sequence ID" value="KPL74383"/>
        <property type="gene ID" value="ADN00_13705"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1317"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005746">
        <property type="entry name" value="Thioredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017937">
        <property type="entry name" value="Thioredoxin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000077">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01068">
        <property type="entry name" value="thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00194">
        <property type="entry name" value="THIOREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2 4" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="5">
        <location>
            <begin position="1"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="4">
        <location>
            <begin position="32"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000077-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL74383.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="117" mass="12936" checksum="ED986186DEDAE0E7" modified="2016-01-20" version="1">MQEPVHVSDESFEKVVLKSSIPVVVDFWAPWCGPCKMIAPALEKFAKEYSGKLLIAKVNTDEHPRWATQFNVQGIPTMLFVANGKVVHRQTGALPEGMLRDIVEQFLEVAGQAQTGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XHA0</accession>
    <name>A0A0P6XHA0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Aspartate--tRNA ligase</fullName>
            <ecNumber evidence="6">6.1.1.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Aspartyl-tRNA synthetase</fullName>
            <shortName evidence="6">AspRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">aspS</name>
        <name evidence="8" type="ORF">ADN00_04830</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the attachment of L-aspartate to tRNA(Asp) in a two-step reaction: L-aspartate is first activated by ATP to form Asp-AMP and then transferred to the acceptor end of tRNA(Asp).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + L-aspartate + tRNA(Asp) = AMP + diphosphate + L-aspartyl-tRNA(Asp)</text>
            <dbReference type="Rhea" id="RHEA:19649"/>
            <dbReference type="Rhea" id="RHEA-COMP:9660"/>
            <dbReference type="Rhea" id="RHEA-COMP:9678"/>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78516"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the class-II aminoacyl-tRNA synthetase family. Type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.12" evidence="6"/>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061823.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04830"/>
    <dbReference type="EnsemblBacteria" id="KPL79175">
        <property type="protein sequence ID" value="KPL79175"/>
        <property type="gene ID" value="ADN00_04830"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.332"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004815">
        <property type="term" value="F:aspartate-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006422">
        <property type="term" value="P:aspartyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02075">
        <property type="entry name" value="Asp_tRNA_synth_type2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004364">
        <property type="entry name" value="Aa-tRNA-synt_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006195">
        <property type="entry name" value="aa-tRNA-synth_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004523">
        <property type="entry name" value="Asp-tRNA_synthase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002312">
        <property type="entry name" value="Asp/Asn-tRNA-synth_IIb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004365">
        <property type="entry name" value="NA-bd_OB_tRNA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43450">
        <property type="entry name" value="PTHR43450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00152">
        <property type="entry name" value="tRNA-synt_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01336">
        <property type="entry name" value="tRNA_anti-codon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01042">
        <property type="entry name" value="TRNASYNTHASP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00458">
        <property type="entry name" value="aspS_nondisc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50862">
        <property type="entry name" value="AA_TRNA_LIGASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6 8" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 6" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II" evidence="7">
        <location>
            <begin position="135"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Aspartate" evidence="6">
        <location>
            <begin position="190"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="362"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="365"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="369"/>
        </location>
        <ligand>
            <name>L-aspartate</name>
            <dbReference type="ChEBI" id="CHEBI:29991"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="410"/>
            <end position="413"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005312"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL79175.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="439" mass="50313" checksum="069440847347ABEB" modified="2016-01-20" version="1">MERTLIGDLRQAIGQKVKISGWLQVLRDQKKMQFLVVRDRTGAVQVVFEKKADPELAEVISTLGSESAITLTGMVVDNPIVKLGGLELVLETLDVVNKAEAPLPFEPFNDTLPSVDFRMDWRYLDLRRQQSLLTFKVQTTAEMAMRDYWMKQGFIEMHSPKIMGTPSESGAELFELAYFDRKAYLAQSPQFFKQMAMAAGFEKVFEIGPVFRADPSFTSRHMTEFTGVDVEISWVDSHEDVMAFQERWLQYVYQQVKDAHGEEIKEVFGFDFEVPSVPFPRVTMAEAIEILRSVGYELPAERKGDIDPGGERALGDYIKQKYNHDFVFVTDWPISVRPFYHMRHPENPGLTRSYDLIAKGLEITTGAQREHRFEVLRTQAFEKGLTEGPIQFYLNYFRYGCPSHGGFGLGLSRLLMVMLNLPNVRDAVYLFRGPNRLEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XIL1</accession>
    <name>A0A0P6XIL1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4126 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_13245</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063499.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000031.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74807">
        <property type="protein sequence ID" value="KPL74807"/>
        <property type="gene ID" value="ADN00_13245"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025196">
        <property type="entry name" value="DUF4126"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13548">
        <property type="entry name" value="DUF4126"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4126" evidence="2">
        <location>
            <begin position="7"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL74807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="189" mass="19867" checksum="BF46E5E457F1F6E8" modified="2016-01-20" version="1">MELFGVFSAFGLSASAGLNAYIPLLVVAFLAKFTNLITLKTPWDALTSWWVIGLLIVLSLVEFFADKFPAVNHINDLIQTFVRPTAGAVAFAASANVITEIHPVLSLGLGLLIAGGVHATKTLAVRPAVTATTGGAGNIPVSILEDVVSTLLSILSVVVPVVIACVLVIVTSWIIFRLLRHSRSHTAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XIY1</accession>
    <name>A0A0P6XIY1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_12950</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL75544">
        <property type="protein sequence ID" value="KPL75544"/>
        <property type="gene ID" value="ADN00_12950"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL75544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="75" mass="8649" checksum="624A75F2A95F677D" modified="2016-01-20" version="1">MLYAAVASKEASNWFQMWQYFNHGLLKFSEILIDNYLPAVWTLFIMTSLGGAGLREPEKSPEKSLPIKGFFFRKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XJ41</accession>
    <name>A0A0P6XJ41_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">5_nucleotid_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_17605</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the 5'-nucleotidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000042">
        <property type="protein sequence ID" value="KPL71215.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064364.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000042.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17605"/>
    <dbReference type="EnsemblBacteria" id="KPL71215">
        <property type="protein sequence ID" value="KPL71215"/>
        <property type="gene ID" value="ADN00_17605"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110165">
        <property type="term" value="C:cellular anatomical entity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016791">
        <property type="term" value="F:phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009166">
        <property type="term" value="P:nucleotide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008334">
        <property type="entry name" value="5'-Nucleotdase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036907">
        <property type="entry name" value="5'-Nucleotdase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006146">
        <property type="entry name" value="5'-Nucleotdase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006179">
        <property type="entry name" value="5_nucleotidase/apyrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11575">
        <property type="entry name" value="PTHR11575"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02872">
        <property type="entry name" value="5_nucleotid_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01607">
        <property type="entry name" value="APYRASEFAMLY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55816">
        <property type="entry name" value="SSF55816"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00785">
        <property type="entry name" value="5_NUCLEOTIDASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="5_nucleotid_C" evidence="2">
        <location>
            <begin position="294"/>
            <end position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU362119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL71215.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="490" mass="53129" checksum="6768C4163C9DFCAD" modified="2016-01-20" version="1">MARKTISVTILHTNDMHADLPAMSRLSAFLRAYRAELLAEGRRVFYFDAGDAADRRVRWISATKGAAFPRVLAAMGCDLQTLGNGISVTYGLQAASDMAARADFPILAVNFFRNGQPLVAGFLPSITFALDDQVSLKVSGQAPYSPHIYALFGVDVPHFVECAREWARKLAGQPGPLVMVNHLGLREDREVAAAVPEVDVIIGGHSHSLLPDGEFVGGVLIAQAGQYAQYLGRVDLEIDAQTGVVLSKKARLLGIPADQAADPLVEAAIGQAEEEARQVLARPIARLPEALEADFFAESALGNYAADALRRRMNAEIGLLASGLLQKGLPAGLLTLGRLDEACFTTANPMLSLLSGRQVREGLEKGLKEENARAYHKSYRGSPVGIPQVSGLRVLWDPAAPDGNKIREVWVGENPLEEDRQYRVAHTDAECEGAGAFLTMEEGQVLRTEVPTILREVLEEDLKRGIPSLNELQGRWIQIFDSFCSIIGCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKQ0</accession>
    <name>A0A0P6XKQ0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">30S ribosomal protein S18</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rpsR</name>
        <name evidence="5" type="ORF">ADN00_15085</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 30S ribosomal subunit. Forms a tight heterodimer with protein S6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the bacterial ribosomal protein bS18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72157.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063866.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15085"/>
    <dbReference type="EnsemblBacteria" id="KPL72157">
        <property type="protein sequence ID" value="KPL72157"/>
        <property type="gene ID" value="ADN00_15085"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.719"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00270">
        <property type="entry name" value="Ribosomal_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001648">
        <property type="entry name" value="Ribosomal_S18"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036870">
        <property type="entry name" value="Ribosomal_S18_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13479">
        <property type="entry name" value="PTHR13479"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01084">
        <property type="entry name" value="Ribosomal_S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00974">
        <property type="entry name" value="RIBOSOMALS18"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46911">
        <property type="entry name" value="SSF46911"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00165">
        <property type="entry name" value="S18"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00270"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003910"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL72157.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="90" mass="10543" checksum="7021FBD283F322CE" modified="2016-01-20" version="1">MDEQSRSFTPGRRFVTRPKICQFCAEANVEIDYKNVDLLRRFVSENGKIRPRRQTGTCARHQREVAKAVKRARHIALLPYTGEPWEDAIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKQ1</accession>
    <name>A0A0P6XKQ1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Methyltransferase</fullName>
            <ecNumber evidence="7">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ADN00_01580</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a 2'-deoxyadenosine in DNA + S-adenosyl-L-methionine = an N(6)-methyl-2'-deoxyadenosine in DNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:15197"/>
            <dbReference type="Rhea" id="RHEA-COMP:12418"/>
            <dbReference type="Rhea" id="RHEA-COMP:12419"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90615"/>
            <dbReference type="ChEBI" id="CHEBI:90616"/>
            <dbReference type="EC" id="2.1.1.72"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the N(4)/N(6)-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="7"/>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80561.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061207.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="REBASE" id="132730">
        <property type="entry name" value="M.OapP3M1ORF1580P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80561">
        <property type="protein sequence ID" value="KPL80561"/>
        <property type="gene ID" value="ADN00_01580"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1075"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002941">
        <property type="entry name" value="DNA_methylase_N4/N6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040843">
        <property type="entry name" value="RAMA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001091">
        <property type="entry name" value="RM_Methyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01555">
        <property type="entry name" value="N6_N4_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18755">
        <property type="entry name" value="RAMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00508">
        <property type="entry name" value="S21N4MTFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N6_N4_Mtase" evidence="8">
        <location>
            <begin position="32"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="RAMA" evidence="9">
        <location>
            <begin position="263"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001279"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF18755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL80561.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="364" mass="41321" checksum="6A99FF9B5F88C28B" modified="2016-01-20" version="1">MSEQPPSSALPLNQVILGDCRQVLATLPKNSVDLIFADPPYNLQLRGELHRPDLSRVDRVDDEWDQFEGFDTYDQFTEEWLSACRRVLKPGGTLWVIGTYHNIYRVGGILQNLGFWILNDIVWVKTNPMPNFRGVRFTNAHETLIWAVKDRRAKYTFNYHAMKSLNDGLQMRSDWHLPICTGRKRLRVNGEKAHSTQKPESLLYRVLLAASNPGDVILDPFFGTGTSGAVAQQLGRQWIGIERDPQYVEIARQRIASLPAAPDETALRATPNPRRQPRIAFGTLLEAGLLRPGQTLYFGAEGSRSAQISADASLEYNGQRGSIHQIARAIQPGPRNGWLCWFYEDPHTGQRRPIDHLRQFIRNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKR7</accession>
    <name>A0A0P6XKR7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_01155</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000003">
        <property type="protein sequence ID" value="KPL80830.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061130.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01155"/>
    <dbReference type="EnsemblBacteria" id="KPL80830">
        <property type="protein sequence ID" value="KPL80830"/>
        <property type="gene ID" value="ADN00_01155"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1976"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032823">
        <property type="entry name" value="BCA_ABC_TP_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12399">
        <property type="entry name" value="BCA_ABC_TP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="5"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL80830.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="270" mass="29868" checksum="65B66314AE92AE8B" modified="2016-01-20" version="1">MQPILETHQLTKIFGGLTAVDSVDLTVPKETIASIIGPNGAGKTTFFNCTSGYYKPEKGEVIFDGKVINRLSTDQITHLGISRTYQNIRLFANMTAIENVMIGHHCRLKSSWLDAVLHTPRFAREERESIQEGRRLLKYVGLEGLGDNLARNLPYGAQRRLEIARALASEPKLLLLDEPTAGMNPQETAEMTTFIRSLRDSLGITILLIEHDMNVVMGISDQISVLDFGTKIAEGTPKEIQSNPRVIEAYLGPGGAALSEKFSRKKHHDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XLQ9</accession>
    <name>A0A0P6XLQ9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Histidine kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_12200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063293.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12200"/>
    <dbReference type="EnsemblBacteria" id="KPL76096">
        <property type="protein sequence ID" value="KPL76096"/>
        <property type="gene ID" value="ADN00_12200"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3916"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016772">
        <property type="term" value="F:transferase activity, transferring phosphorus-containing groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="19"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="49"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="86"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="111"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="147"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="173"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="538"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="421"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL76096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="768" mass="84218" checksum="A58D634FEE7C6097" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XMA7</accession>
    <name>A0A0P6XMA7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Phosphatidate cytidylyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_00035</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL80982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060911.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00035"/>
    <dbReference type="EnsemblBacteria" id="KPL80982">
        <property type="protein sequence ID" value="KPL80982"/>
        <property type="gene ID" value="ADN00_00035"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039606">
        <property type="entry name" value="Phytol/farnesol_kinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32523">
        <property type="entry name" value="PTHR32523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="39"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="103"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="127"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="166"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="193"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL80982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="237" mass="25424" checksum="EB433831E6B879A5" modified="2016-01-20" version="1">MLNNIWIAFGVTFAAALIWLRVNDFLAHRGFISGPLSRKLIHMGTGPIFVLCWLLFPDTLTSRFLAALIPLAITVQFALVGLGVVKDQAAVDAMSRTGQREEILRGPLFYGIVFVVLTLVYWRDSLIGIVALMLLCGGDGLADIVGKRIKSAAIPWARKKSVAGTLAMFAGGWLMSVGVGVVYQASGFLPGDLVNYLPAITVIALAGMMVESLPFSDIDNLTVPAVAVLLGHLLLPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XMC4</accession>
    <name>A0A0P6XMC4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Response regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_00140</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060931.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00140"/>
    <dbReference type="EnsemblBacteria" id="KPL81000">
        <property type="protein sequence ID" value="KPL81000"/>
        <property type="gene ID" value="ADN00_00140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="4"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL81000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="118" mass="13573" checksum="B3C673B70961CB55" modified="2016-01-20" version="1">MSKKILLVEDDRTMLNLLKTLLQIEGFEVVVIDEKSDTDLFSILQAERPDIVLMDVLLKFSNGLDLTQSIRNMEDFNSMKIILTSGIDYKHQAKNAGADYFLQKPYMPDILIHLLKEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XMF6</accession>
    <name>A0A0P6XMF6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Ornithine carbamoyltransferase</fullName>
            <shortName evidence="5">OTCase</shortName>
            <ecNumber evidence="3 5">2.1.3.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_15030</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>carbamoyl phosphate + L-ornithine = H(+) + L-citrulline + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19513"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:57743"/>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
            <dbReference type="EC" id="2.1.3.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.3" evidence="3 5"/>
    <dbReference type="EMBL" id="LGCL01000036">
        <property type="protein sequence ID" value="KPL73099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063852.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000036.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15030"/>
    <dbReference type="EnsemblBacteria" id="KPL73099">
        <property type="protein sequence ID" value="KPL73099"/>
        <property type="gene ID" value="ADN00_15030"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1870"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016597">
        <property type="term" value="F:amino acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004585">
        <property type="term" value="F:ornithine carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1370">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01109">
        <property type="entry name" value="OTCase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006132">
        <property type="entry name" value="Asp/Orn_carbamoyltranf_P-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006130">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036901">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006131">
        <property type="entry name" value="Asp_carbamoyltransf_Asp/Orn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002292">
        <property type="entry name" value="Orn/put_carbamltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024904">
        <property type="entry name" value="OTCase_ArgI"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00185">
        <property type="entry name" value="OTCace"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02729">
        <property type="entry name" value="OTCace_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00100">
        <property type="entry name" value="AOTCASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00102">
        <property type="entry name" value="OTCASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53671">
        <property type="entry name" value="SSF53671"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00658">
        <property type="entry name" value="orni_carb_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="OTCace_N" evidence="8">
        <location>
            <begin position="3"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="domain" description="OTCace" evidence="7">
        <location>
            <begin position="149"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Carbamoyl phosphate binding" evidence="5">
        <location>
            <begin position="130"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Ornithine binding" evidence="5">
        <location>
            <begin position="229"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Carbamoyl phosphate binding" evidence="5">
        <location>
            <begin position="265"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="103"/>
        </location>
        <ligand>
            <name>carbamoyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>L-ornithine</name>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="225"/>
        </location>
        <ligand>
            <name>L-ornithine</name>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="293"/>
        </location>
        <ligand>
            <name>carbamoyl phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58228"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007805"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL73099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="308" mass="33776" checksum="B87B0D640A09CCAC" modified="2016-01-20" version="1">MNKDFIAISDYAPQEIQDILDLAIRLKEEWKAGGNQPILKNKVLGMIFQKPSLRTRVSFDMAMRHLGGDALYLSPNEIGLGKRESIADIARVMSGYVSAIMARVFDHQHVVELAKWSSIPVINGLSDYNHPCQGMADAMTILEYKGTLKGKNVTFVGDGNNVAVSLLHVCSMLGANFTIAGPEGFDIPLNALEVGQKFAAQSGSKIRSMRDVHAAVADADVIYTDTWTSMGQEEETARREQAFASYQVNASLVAEAKPDVIVMHCLPAHRGQEITDEVADGPHSALFPQAHNRLHAQKAILVHLLRED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XMG6</accession>
    <name>A0A0P6XMG6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_14965</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000036">
        <property type="protein sequence ID" value="KPL73108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14965"/>
    <dbReference type="EnsemblBacteria" id="KPL73108">
        <property type="protein sequence ID" value="KPL73108"/>
        <property type="gene ID" value="ADN00_14965"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009943">
        <property type="entry name" value="DUF1475"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07343">
        <property type="entry name" value="DUF1475"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL73108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="98" mass="11449" checksum="66DD2A66DDBB3411" modified="2016-01-20" version="1">MTAVLIYAFTRGNFFTEGSQLLSMPWGIVSLVDLYVGFSLFSMWVIYREKSALKSIIWVAFIMVLGFFTVSFYIYIALQSSRDDWNRFFHGRRYSLSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XMN4</accession>
    <name>A0A0P6XMN4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable glycine dehydrogenase (decarboxylating) subunit 1</fullName>
            <ecNumber evidence="4">1.4.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Glycine cleavage system P-protein subunit 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Glycine decarboxylase subunit 1</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Glycine dehydrogenase (aminomethyl-transferring) subunit 1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">gcvPA</name>
        <name evidence="5" type="ORF">ADN00_00880</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 4">The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>(R)-N(6)-lipoyl-L-lysyl-[glycine-cleavage complex H protein] + glycine + H(+) = (R)-N(6)-(S(8)-aminomethyldihydrolipoyl)-L-lysyl-[glycine-cleavage complex H protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:24304"/>
            <dbReference type="Rhea" id="RHEA-COMP:10494"/>
            <dbReference type="Rhea" id="RHEA-COMP:10495"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83143"/>
            <dbReference type="EC" id="1.4.4.2"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the GcvP family. N-terminal subunit subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.4.2" evidence="4"/>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061061.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00880"/>
    <dbReference type="EnsemblBacteria" id="KPL81110">
        <property type="protein sequence ID" value="KPL81110"/>
        <property type="gene ID" value="ADN00_00880"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3574"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004375">
        <property type="term" value="F:glycine dehydrogenase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019464">
        <property type="term" value="P:glycine decarboxylation via glycine cleavage system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00613">
        <property type="entry name" value="GDC-P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00712">
        <property type="entry name" value="GcvPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023010">
        <property type="entry name" value="GcvPA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020581">
        <property type="entry name" value="GDC_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42806">
        <property type="entry name" value="PTHR42806"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02347">
        <property type="entry name" value="GDC-P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006815">
        <property type="entry name" value="GcvPA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00033655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00712"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL81110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="449" mass="49180" checksum="D65A9EFF001AE610" modified="2016-01-20" version="1">MFTPHTEKERAEMLKTIGVDKIEDLFTDVPEKVRFPKLDLPEALSEMEALQQVRELASANESAQDLACFLGAGAYHHYTPAAVDNLLRRGEFYTAYTPYQPEVSQGTLQAIFEFQSLIAGLTGMEVTNASHYDGATAVAEAGIMAFHHFRGKRTKFIASPALNPQYRDVLCTYVCGMGGAQVITPNLESPLSDPADLLSLVDDQTALVVVQYPDFFGRIFDYSAIAEKVHEAGALLAVAVNPLSLGLLKPPGEFGADIVIGEGQSLGLPLSYGGPYLGLFSTRKELVRKVAGRLVGETEDKNGNRGYVLTLTAREQHIRREKATSNICTNQGLMALAAAIYLSLLGKNGLRKVAELCYHKAHYAAKKINQIKGFKVLVDSPFFNEFIVETPIPVDELNLYLLDQGILGGYDLKKAYPNMKNAMLVAVTEMNSRGEIDLLCDVLREVSHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XMS8</accession>
    <name>A0A0P6XMS8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B</fullName>
            <shortName evidence="10">Asp/Glu-ADT subunit B</shortName>
            <ecNumber evidence="10">6.3.5.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="primary">gatB</name>
        <name evidence="12" type="ORF">ADN00_11195</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9 10">Allows the formation of correctly charged Asn-tRNA(Asn) or Gln-tRNA(Gln) through the transamidation of misacylated Asp-tRNA(Asn) or Glu-tRNA(Gln) in organisms which lack either or both of asparaginyl-tRNA or glutaminyl-tRNA synthetases. The reaction takes place in the presence of glutamine and ATP through an activated phospho-Asp-tRNA(Asn) or phospho-Glu-tRNA(Gln).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>ATP + H2O + L-aspartyl-tRNA(Asn) + L-glutamine = ADP + 2 H(+) + L-asparaginyl-tRNA(Asn) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14513"/>
            <dbReference type="Rhea" id="RHEA-COMP:9674"/>
            <dbReference type="Rhea" id="RHEA-COMP:9677"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78515"/>
            <dbReference type="ChEBI" id="CHEBI:78516"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 10">
            <text>ATP + H2O + L-glutamine + L-glutamyl-tRNA(Gln) = ADP + H(+) + L-glutamate + L-glutaminyl-tRNA(Gln) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:17521"/>
            <dbReference type="Rhea" id="RHEA-COMP:9681"/>
            <dbReference type="Rhea" id="RHEA-COMP:9684"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:78520"/>
            <dbReference type="ChEBI" id="CHEBI:78521"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4 10">Heterotrimer of A, B and C subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the GatB/GatE family. GatB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.5.-" evidence="10"/>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063100.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11195"/>
    <dbReference type="EnsemblBacteria" id="KPL76526">
        <property type="protein sequence ID" value="KPL76526"/>
        <property type="gene ID" value="ADN00_11195"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.935"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050566">
        <property type="term" value="F:asparaginyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050567">
        <property type="term" value="F:glutaminyl-tRNA synthase (glutamine-hydrolyzing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00121">
        <property type="entry name" value="GatB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004413">
        <property type="entry name" value="Apn/Gln-ADT_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017959">
        <property type="entry name" value="Asn/Gln-tRNA_amidoTrfase_suB/E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006075">
        <property type="entry name" value="Asn/Gln-tRNA_Trfase_suB/E_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018027">
        <property type="entry name" value="Asn/Gln_amidotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003789">
        <property type="entry name" value="Asn/Gln_tRNA_amidoTrase-B-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042114">
        <property type="entry name" value="GatB_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023168">
        <property type="entry name" value="GatB_Yqey_C_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017958">
        <property type="entry name" value="Gln-tRNA_amidoTrfase_suB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014746">
        <property type="entry name" value="Gln_synth/guanido_kin_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11659">
        <property type="entry name" value="PTHR11659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02934">
        <property type="entry name" value="GatB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02637">
        <property type="entry name" value="GatB_Yqey"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00845">
        <property type="entry name" value="GatB_Yqey"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55931">
        <property type="entry name" value="SSF55931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89095">
        <property type="entry name" value="SSF89095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00133">
        <property type="entry name" value="gatB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01234">
        <property type="entry name" value="GATB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 10" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 10" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GatB_Yqey" evidence="11">
        <location>
            <begin position="328"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KPL76526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="478" mass="53966" checksum="85DFF8F7EB08553F" modified="2016-01-20" version="1">MTEYEVVIGLETHIQLNTQTKIFCACKADSWEDAPNTNICPVCTGQPGVLPVMNKTAVEKAVLLATAMNAQPQPVSFFDRKNYFYPDLPKGYQISQYDQPIAKGGYLDLPMPDGSTRRVGIEKLHLEEDAGKTKNEHGRRLIDFNRCGVPLVEMVTKPDLRSADEAAQYLTRLRQLLRWLGVSEADMEKGHLRCDANVSIRPKCATHLNTKTEIKNVNSIDAVREAILKEVERQIREVEAGGTIKPWTLDWDDAKKRLTVMRSKETEADYRYFREPDLLPIYLDEAWKQRILASFPELPLQRRQRFIAEYQLPEYDAEVLTSERSLSEYFESAVKAYGGDPKKVSNILMNDVLRMLNDRGISAEQTRLQPAFLAEILKLVDARTINLNTGKKLITKVEETGKSPADLVKEEGLGQVSDDSEIRKACAEIVAANPGEVESYKAGKETLIGWFVGQVMRSMRGKANPQLARAIMEELLKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XNL3</accession>
    <name>A0A0P6XNL3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH tetR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_09680</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76864.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062799.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76864">
        <property type="protein sequence ID" value="KPL76864"/>
        <property type="gene ID" value="ADN00_09680"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="3"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL76864.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="206" mass="23569" checksum="4B2B830D86D15CC3" modified="2016-01-20" version="1">MNKDGKLKIIEAAQRLIACQGVEKTSMRDIAEEAGITTGAIYYYYKSKEELLYDVMDYATAVTAEIMKMRSRPDAKPEEVLDEIARKVTQQLKNHRHWNLRFYLALQAAQGDETLRARFASNYAAQTQRTADLFNYVFGTQAHPQDLDLAVLMVAALDGINFQQFIGALPVEIDELARVYNEFFAFAVPLYEKNREAIHRFQNSQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XPK1</accession>
    <name>A0A0P6XPK1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_13950</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063641.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000033.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74104">
        <property type="protein sequence ID" value="KPL74104"/>
        <property type="gene ID" value="ADN00_13950"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL74104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="216" mass="23372" checksum="F9C7829323142CAC" modified="2016-01-20" version="1">MSAYDEVSQRALQLLGDPLDGQYPAAVLAEAARRALEAFSRCAPRIESVAWVVESASARQALPLAGAWLVLDVEWRAASGILRAGRPWQIVWQDGQPLIEWLSAPYPQPGDGLLARCALNHSLEGLDGAPQSSVKAADLGLLAQGAAGYAAQMRAAQLTESYGSRASDLGQLAAWGGGQLQRFEQRLAEEARRSGVEIPWALPQRGWPCDRWEVCR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XPX2</accession>
    <name>A0A0P6XPX2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltransf_11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09285</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77312.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062713.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09285"/>
    <dbReference type="EnsemblBacteria" id="KPL77312">
        <property type="protein sequence ID" value="KPL77312"/>
        <property type="gene ID" value="ADN00_09285"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransf_11" evidence="1">
        <location>
            <begin position="80"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77312.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="226" mass="25886" checksum="D000E19F9E5026E3" modified="2016-01-20" version="1">MKFGIVRKTIHHVVQKNMGEMRRGKYQSVLQELQAGATVVDIGVWCKMPEPNVNENWLEKQAPGSGKLIAVGLDSMQAFQKKYPEVICVQANGMALPFKDGAVDIAISNAVLEHVPMEGHKDFVFEITRIVKRVAIFAVPDRAFPVEVHSRIPFLHWLPNWREVFRLVGEKNWASKEYLATIFTIRSLKNLIYSVRPKKTWQIKRQKFFGWPVSLIAAFSPQKQSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XPY4</accession>
    <name>A0A0P6XPY4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062060.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78781">
        <property type="protein sequence ID" value="KPL78781"/>
        <property type="gene ID" value="ADN00_05990"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133169" evidence="1">
        <location>
            <begin position="22"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="216" mass="22761" checksum="CA1C616B3A90C458" modified="2016-01-20" version="1">MKSLKISLLVTIIVSLSVLLAACDIRLTATPDTVSASENGGNGGNADAGEIAFLEEQLSNPELDEQTRASLQEKLDMAIRIATLQAATPVPGAQVQALDAVGGEGEEIPFNSGIFPGDEGLFKPSQALIENYWQEKVGEEYVQVFAGASGENPQQGLVIVVVTQADLVNSTTDFYPAAEASGSLHITEATPELVRMENQDGQAFCFKLAEGSFGCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQ04</accession>
    <name>A0A0P6XQ04_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_09415</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77331.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062737.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09415"/>
    <dbReference type="EnsemblBacteria" id="KPL77331">
        <property type="protein sequence ID" value="KPL77331"/>
        <property type="gene ID" value="ADN00_09415"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014757">
        <property type="entry name" value="Tscrpt_reg_IclR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005471">
        <property type="entry name" value="Tscrpt_reg_IclR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09339">
        <property type="entry name" value="HTH_IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01614">
        <property type="entry name" value="IclR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00346">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51077">
        <property type="entry name" value="HTH_ICLR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51078">
        <property type="entry name" value="ICLR_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH iclR-type" evidence="3">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="domain" description="IclR-ED" evidence="4">
        <location>
            <begin position="64"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51077"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL77331.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="251" mass="28103" checksum="FE5CFA9C91D705AA" modified="2016-01-20" version="1">MQTIERVNAILDCFTLERPELGVREAARLIGLSTSTTGRMLAAMKELGILTQNPTTHTYALGGKVLKWAGVYSETLDVRARSMPMLEELHRSTQETISLYVMEGNERVCVERLESPQNVRIVARVGRRLPLYAGSAGKVFLAFLPEARRDEIIRHTDFKPLTSNTIVDEHALRDELTKIRRQGYSLSRGEWLSDAAGVAAPIFDQSGLIVAAVTISGPAQRFTEEKVNQYIPEILHVGEQISRYLGYLGRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQ32</accession>
    <name>A0A0P6XQ32_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_06415</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062133.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78845">
        <property type="protein sequence ID" value="KPL78845"/>
        <property type="gene ID" value="ADN00_06415"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12710">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038375">
        <property type="entry name" value="NDUFAF7_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="493" mass="55893" checksum="01420AD91622F28B" modified="2016-01-20" version="1">MVGNGLEKNEVIDAELIEKNQRLSHSILWRLHSAFYQQSGVTAWNRGHVPHYITNNPTIAAAYAHLVLDYLQNLTIHSPQQPVFILELGGGSGRFAFYFLNYFLPETRHLFPQGTRFVYLLTDLAESNLNFWKTHPALQPFLRSGELELACFNPLTDHQISLTSSGTTLTRQDIANPLIVLGNYFFDSLPNDVFSIHGGILCEELVSLKTRKPLLDPVGPSILPSLEISFRPRFISAPYYHNQKYNRLLRQYLAAFSDSYVLMPIGALECLRNLLWLSRGKMYFLSADKGDFQLNALQGLNQPEISLHGSAISMKVNYHALAAFTRQSGGQAFQSKHRDEGLVFSTFLFGASANLLQSARRAFNMTFETASPDDFFVWKKALQPYYSQLPLEQLLAILRLSGYDPQIFGETFHLLLEYAQTADPRQKDWIAEAARRVFLLYYPIGEALNLYLPLARLFLSLSRQPEAQACQRASREFFGPSTEMDTLLAQTTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQS6</accession>
    <name>A0A0P6XQS6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_04710</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061802.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04710"/>
    <dbReference type="EnsemblBacteria" id="KPL79156">
        <property type="protein sequence ID" value="KPL79156"/>
        <property type="gene ID" value="ADN00_04710"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="211" mass="22659" checksum="8F396C58B14A0870" modified="2016-01-20" version="1">MTDTALIWGASGGIGRGLVESLVDHGWQVAAVARRGDSSVGPATWTAEADASDEAAVQRAVQELAQQAGEVNWWIYAAGDILSSPLEKMELKDWQRILQANLTGVYLTAKYSLPLLAPGAPLYILGAVSERMRLPGLSAYAAAKSGVEALAEVMKKDLRRTVVVVRPGAVKTALWDKVPFKAPPSAISPQDLAKKMLTAYQQGYKELKLDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XR82</accession>
    <name>A0A0P6XR82_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13555</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ROK (NagC/XylR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063559.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000031.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74854">
        <property type="protein sequence ID" value="KPL74854"/>
        <property type="gene ID" value="ADN00_13555"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="405" mass="43945" checksum="DE1A8AEB190ACCB3" modified="2016-01-20" version="1">MAKPKTANQTLVREMNASIVMDCIRLYAPLSRADLAARTGLMRSTISLIVDELIGHSFVREIHRQGSKVGRPGTLLEVNPNAGFAVGLEVGVDFLAVIVTNFVGEILWRRTQATPESQHQIAKLEQVEQVIAEALEAGKSLGLRPLGIGVGVPGLVDAEQGKLVFAPNLHWMDVPLRLIWTRRFGLPVFVENEANCACLGEYFYGNARNIENFIFLKTGVGLGGGVMIDGKLFRGANGYGGEIGHMALYKGGELCACGRHGCWETYVRPSNLYRDIILRLKDGNKSMIADLVGGDLYKITMDEVIEAAQQGDAVVLSVLEDYARHLAFGICNLINIFNPELVILGGTLSGAGQWLVPAINASMQQNVMPPLRNITRIEVSARGEDACLLGAIALVLDDILREPLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XRH3</accession>
    <name>A0A0P6XRH3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">30S ribosomal protein S16</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rpsP</name>
        <name evidence="4" type="ORF">ADN00_08250</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the bacterial ribosomal protein bS16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77861.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062511.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08250"/>
    <dbReference type="EnsemblBacteria" id="KPL77861">
        <property type="protein sequence ID" value="KPL77861"/>
        <property type="gene ID" value="ADN00_08250"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.652"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00385">
        <property type="entry name" value="Ribosomal_S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000307">
        <property type="entry name" value="Ribosomal_S16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023803">
        <property type="entry name" value="Ribosomal_S16_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12919">
        <property type="entry name" value="PTHR12919"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00886">
        <property type="entry name" value="Ribosomal_S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54565">
        <property type="entry name" value="SSF54565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00002">
        <property type="entry name" value="S16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL77861.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="114" mass="13147" checksum="DD830925609C51FB" modified="2016-01-20" version="1">MVRIRLRRVGLRKQASYRIIAADKESPRDGKFLEILGFYNPRTEPSTIEVKEDRVFDWMSKGAQPSESVEKLFKSIGLLDRFARYKGGESIEVLLSEAEARKASQKVDARTRRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XRL5</accession>
    <name>A0A0P6XRL5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_08480</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77897">
        <property type="protein sequence ID" value="KPL77897"/>
        <property type="gene ID" value="ADN00_08480"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="75" mass="8533" checksum="530A0EE92B54FCC4" modified="2016-01-20" version="1">MDLQNTLEATLKTHFQPVLPDQGFVNTLRTKLITPAPTFMEPQKNQHALWLVFVGLASGLALVWILGLFRKWSDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XSY3</accession>
    <name>A0A0P6XSY3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Acylneuraminate cytidylyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_11980</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063251.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11980"/>
    <dbReference type="EnsemblBacteria" id="KPL76061">
        <property type="protein sequence ID" value="KPL76061"/>
        <property type="gene ID" value="ADN00_11980"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3872"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003329">
        <property type="entry name" value="Cytidylyl_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02348">
        <property type="entry name" value="CTP_transf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="226" mass="26014" checksum="31EEDBDAF0E9B48E" modified="2016-01-20" version="1">MMKDKMKIAALVPMRHHSQRVPGKNYRPLAGRPLYQHILDTLLACPEIDDIVVDTDSPEILEGLDRQYPGVIALERPESLRADDIPMNEILLHDTAQVQADLYLQTHSTNPLLRAETISNAIQALVSSYPAFDSLFSATRLQTRLWDELTRPINHNPAILLQTQDLPPVYEENSCIYIFTRENLLRRRNRLGDRPLMFKMEADESWDIDEEIDFLIADAILSQRLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XT28</accession>
    <name>A0A0P6XT28_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_11935</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76171.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11935"/>
    <dbReference type="EnsemblBacteria" id="KPL76171">
        <property type="protein sequence ID" value="KPL76171"/>
        <property type="gene ID" value="ADN00_11935"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3863"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007156">
        <property type="term" value="P:homophilic cell adhesion via plasma membrane adhesion molecules"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006644">
        <property type="entry name" value="Cadg"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002126">
        <property type="entry name" value="Cadherin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015919">
        <property type="entry name" value="Cadherin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00028">
        <property type="entry name" value="Cadherin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00205">
        <property type="entry name" value="CADHERIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00112">
        <property type="entry name" value="CA"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00736">
        <property type="entry name" value="CADG"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49313">
        <property type="entry name" value="SSF49313"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50268">
        <property type="entry name" value="CADHERIN_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cadherin" evidence="1">
        <location>
            <begin position="31"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="1">
        <location>
            <begin position="137"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="1">
        <location>
            <begin position="232"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="1">
        <location>
            <begin position="339"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="domain" description="Cadherin" evidence="1">
        <location>
            <begin position="440"/>
            <end position="535"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76171.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="535" mass="57291" checksum="4834171F045E5CF9" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XTC0</accession>
    <name>A0A0P6XTC0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_07700</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78327.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062398.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78327">
        <property type="protein sequence ID" value="KPL78327"/>
        <property type="gene ID" value="ADN00_07700"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3370"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="181"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="213"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="238"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="267"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="31"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="152"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78327.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="310" mass="32694" checksum="8F3150EDFA2B88E8" modified="2016-01-20" version="1">MRDGKSILPYLALGGGVLALTLSSLFVRWAQAPGVVTSFYRMAIAALLLVPLGLRSWRGLPAFSPGLLVFPLIGGLFTSLDHGFWSTSIQFTRVANATLLNNIAPLWVALLSYLFWRQRLSGRFWVGLACALSGAAVVLASDLILHPHFSGGDALALLSSVFYAAYFLVTQQGRKKLPALAYIWLMTAASAVCLLAASLGMGYSLGGYSRETWLAFVGAAVISQVGGYFMVSYALGHLPAAVVSPTMIAQPVLTALAAIPLVGEHLAIWQLLGGGVVLLGVYLVNTAQPQKETSPAEAGLVEAQNDTAGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XTJ5</accession>
    <name>A0A0P6XTJ5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_11085</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76509.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063078.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76509">
        <property type="protein sequence ID" value="KPL76509"/>
        <property type="gene ID" value="ADN00_11085"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="44"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="117"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL76509.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="264" mass="28787" checksum="E6A5A4B6C49DDC58" modified="2016-01-20" version="1">MENKEMPSENELPAEGDASLSGQVEPAAEAVEAFETIETVETAQASATSESVVEEPRFTPPPVTEVGTQPSVLERFSHWLLDKETSRGRFMRSALRWTAVALAAFVVGLIVFYFWQYRPLQARLQDTQTQLEAAQAEAVSLQGDLDDANAANEDLSAANTALEEDVRIATARVLIAQIQSKALNARLQLNIRQGAAAQKSLKEAKDLLTDLDEVLGEDSAQVLEQMETRLAAATSSLISDPTVAIKDLETFDTLLAQQEKILSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUF9</accession>
    <name>A0A0P6XUF9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">bPH_5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_10665</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77021.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062982.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77021">
        <property type="protein sequence ID" value="KPL77021"/>
        <property type="gene ID" value="ADN00_10665"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027783">
        <property type="entry name" value="Bacterial_PH-related"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10882">
        <property type="entry name" value="bPH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="15"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="203"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="247"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="275"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="domain" description="bPH_5" evidence="2">
        <location>
            <begin position="74"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77021.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="300" mass="32609" checksum="384A661EF4F419CC" modified="2016-01-20" version="1">MPQATVFHPARRTGLLINIPAAVLLLGGSAAFIWLSAQQQVGSSFLLLLLLALALLAPLPLVAYRIYALLQSGYTLDRESLTLRWGLRSQVIPIYDVEWIRPADELGFHLPLPRLGWPGAYLGARSVEGLGLVEFMAAETDGMLLVATPERIYVISPTQPRDFINTFLRSAEMGSLSRVAAVSSRPAAFLQEVWSDHLARGMLLAGVGLTLALFILVTLLIPSRAQISLGFLPNGAPVEPGPSERLLLLPVLAGLVTAADVALGLYFYRHEDQRLAGYFIWSASGLTALLLIIATFFLIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUU1</accession>
    <name>A0A0P6XUU1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AMMECR1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_03420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061562.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03420"/>
    <dbReference type="EnsemblBacteria" id="KPL78958">
        <property type="protein sequence ID" value="KPL78958"/>
        <property type="gene ID" value="ADN00_03420"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.34"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.700.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023473">
        <property type="entry name" value="AMMECR1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036071">
        <property type="entry name" value="AMMECR1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002733">
        <property type="entry name" value="AMMECR1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027485">
        <property type="entry name" value="AMMECR1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027623">
        <property type="entry name" value="AmmeMemoSam_A"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13016">
        <property type="entry name" value="PTHR13016"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01871">
        <property type="entry name" value="AMMECR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143447">
        <property type="entry name" value="SSF143447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04335">
        <property type="entry name" value="AmmeMemoSam_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00296">
        <property type="entry name" value="TIGR00296"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51112">
        <property type="entry name" value="AMMECR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMMECR1" evidence="1">
        <location>
            <begin position="10"/>
            <end position="191"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="191" mass="21544" checksum="71F91CB9F1071007" modified="2016-01-20" version="1">MTIAHLLSPEDQQILLRLARLSIEAAVRDEDPPALKLEDYSPALQEEGAAFVTLTRSGKLRGCIGAIEAYQPLVQDVCEHAAAAATQDFRFEPVRPEELESLEIEISRLTRPMPLAYSSPEDLVSKLRPGIDGVVIKEGFRRATFLPQVWEKLPDPKDFLHNLCHKMGAPGNYWQTHTLEVLVYQVEEFHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUW3</accession>
    <name>A0A0P6XUW3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_08960</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08960"/>
    <dbReference type="EnsemblBacteria" id="KPL77259">
        <property type="protein sequence ID" value="KPL77259"/>
        <property type="gene ID" value="ADN00_08960"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4026"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901564">
        <property type="term" value="P:organonitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006796">
        <property type="term" value="P:phosphate-containing compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044238">
        <property type="term" value="P:primary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.350">
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR042240">
        <property type="entry name" value="CHASE_sf"/>
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        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037522">
        <property type="entry name" value="HD_GYP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03924">
        <property type="entry name" value="CHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01079">
        <property type="entry name" value="CHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50839">
        <property type="entry name" value="CHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51832">
        <property type="entry name" value="HD_GYP"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="193"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="235"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="CHASE" evidence="7">
        <location>
            <begin position="297"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="5">
        <location>
            <begin position="583"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="6">
        <location>
            <begin position="658"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="5">
        <location>
            <begin position="713"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="6">
        <location>
            <begin position="778"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="domain" description="HD-GYP" evidence="8">
        <location>
            <begin position="1160"/>
            <end position="1349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL77259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="1349" mass="153688" checksum="0A1D6C90E4A91AF6" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUX1</accession>
    <name>A0A0P6XUX1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 7">UDP-glucose 6-dehydrogenase</fullName>
            <ecNumber evidence="4 7">1.1.1.22</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">ADN00_03685</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>H2O + 2 NAD(+) + UDP-alpha-D-glucose = 3 H(+) + 2 NADH + UDP-alpha-D-glucuronate</text>
            <dbReference type="Rhea" id="RHEA:23596"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58052"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="EC" id="1.1.1.22"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Nucleotide-sugar biosynthesis; UDP-alpha-D-glucuronate biosynthesis; UDP-alpha-D-glucuronate from UDP-alpha-D-glucose: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.22" evidence="4 7"/>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061614.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03685"/>
    <dbReference type="EnsemblBacteria" id="KPL79004">
        <property type="protein sequence ID" value="KPL79004"/>
        <property type="gene ID" value="ADN00_03685"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.89"/>
    <dbReference type="UniPathway" id="UPA00038">
        <property type="reaction ID" value="UER00491"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003979">
        <property type="term" value="F:UDP-glucose 6-dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006065">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
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        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR014027">
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    </dbReference>
    <dbReference type="InterPro" id="IPR036220">
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    </dbReference>
    <dbReference type="InterPro" id="IPR014026">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_dimer"/>
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        <property type="entry name" value="UDP-Glc/GDP-Man_DH_N"/>
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        <property type="entry name" value="UDPglc_DH_bac"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00984">
        <property type="entry name" value="UDPG_MGDP_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03721">
        <property type="entry name" value="UDPG_MGDP_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500134">
        <property type="entry name" value="UDPglc_DH_bac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000124">
        <property type="entry name" value="UDPglc_GDPman_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00984">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF52413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03026">
        <property type="entry name" value="NDP-sugDHase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7 10" id="KW-0520">NAD</keyword>
    <keyword evidence="5 7" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDPG_MGDP_dh_C" evidence="11">
        <location>
            <begin position="315"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="154"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="9">
        <location>
            <begin position="251"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="8">
        <location>
            <position position="262"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="36"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="122"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="157"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="206"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="259"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="265"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="322"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="329"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000874"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR000124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR500134-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR500134-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR500134-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KPL79004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="441" mass="48539" checksum="438C375EB9BDE78B" modified="2016-01-20" version="1">MSKICVIGTGYVGLVTGTCFADLGNDVMCLDVDETRISKLNQNIMPIYEPGLEQVVSANRKAGRLTFTTNFEEALEDADFAFIAVGTPSGVDGEADLQYVRSAAEAVADLVNHPIVVVNKSTVPVGTGDWVADIIKKRRAGKPLEFSVVSNPEFLREGSALNDFMKPDRVVLGSTNRDAANQVAQLYNTLRCPILITDLRTAEMIKYASNAFLATRISFINEIANICEELGADVTEVATGMGYDNRIGRAFLDAGLGWGGSCFPKDVKALAHMAVLHGTQPQLLQAVMDINRNQRRRIIFKLRKALGNLNEKVIGVLGLSFKPNTDDIREAPSLEIVHLLQNEGAVVKAYDPQAMENASAMMKNIVLCDNPYQVAEGADAIILATEWNEFRQIDFERLHKAMRQPIIMDGRNLWDPNQLKEMGFVYFGVGRGTHMTNNNHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XWU7</accession>
    <name>A0A0P6XWU7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_14490</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the glycosyl hydrolase 5 (cellulase A) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000034">
        <property type="protein sequence ID" value="KPL73767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063742.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000034.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14490"/>
    <dbReference type="EnsemblBacteria" id="KPL73767">
        <property type="protein sequence ID" value="KPL73767"/>
        <property type="gene ID" value="ADN00_14490"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1418"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901136">
        <property type="term" value="P:carbohydrate derivative catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041036">
        <property type="entry name" value="GH5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001547">
        <property type="entry name" value="Glyco_hydro_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013780">
        <property type="entry name" value="Glyco_hydro_b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00150">
        <property type="entry name" value="Cellulase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18564">
        <property type="entry name" value="Glyco_hydro_5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cellulase" evidence="4">
        <location>
            <begin position="57"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="Cellulase" evidence="4">
        <location>
            <begin position="348"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_hydro_5_C" evidence="5">
        <location>
            <begin position="541"/>
            <end position="613"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361153"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF18564"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL73767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="627" mass="69905" checksum="04CF3490BAF92E37" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XXG8</accession>
    <name>A0A0P6XXG8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_07850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000020">
        <property type="protein sequence ID" value="KPL78081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062437.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000020.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07850"/>
    <dbReference type="EnsemblBacteria" id="KPL78081">
        <property type="protein sequence ID" value="KPL78081"/>
        <property type="gene ID" value="ADN00_07850"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025699">
        <property type="entry name" value="ABC2_memb-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13346">
        <property type="entry name" value="ABC2_membrane_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="35"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="183"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="217" mass="23999" checksum="ABE112D5D6E61D6F" modified="2016-01-20" version="1">MKALLLKELKLAMHPTTYLFMAIGSMLMIPSYPYYVAFVYTCLGIFFIFLSARENKDIFFTASLPVRKSDVVKSRVVTVAIIELLQLAIGIPFAIIGIRINPNAAGNLAGIEANMAFFGLVLIMYGLFNAIYLPLFYKTAVKVGIPLIFASIAVTIYVVAVELAVQMIPVLKTHLDTTDPAMAIYQFPILIAGLLTFALALWLTYRKSAANFEKVDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XXU7</accession>
    <name>A0A0P6XXU7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Lactamase_B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000003">
        <property type="protein sequence ID" value="KPL80814.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061114.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01070"/>
    <dbReference type="EnsemblBacteria" id="KPL80814">
        <property type="protein sequence ID" value="KPL80814"/>
        <property type="gene ID" value="ADN00_01070"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="20"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80814.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="281" mass="31501" checksum="A60E22D05467E5B0" modified="2016-01-20" version="1">MQRERVSENVYWFQSDVYAQVTAGVVVGPQWALVIDTLALPEETLAMRSFIEEHLNVPVRYIVNTHYHADHTWGNCFFPGATIIAHTLCRKFMLEKGQEALDQAKKQSNALRQVKLVLPHITFSSGNMNLRVGKKNLILMPFPGHSPDALSILIEEDRVFFAGDVFMNLPYIVDGDLEQMRGSIKTISEMGLENIIQGHGDIILRGEIDDAITENLRYLDCIEKAVHNALKRSDPGEYLAQIDVESCGKSRVLLGGLAQDLHQRNLVALYRKMAAQKSAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XY15</accession>
    <name>A0A0P6XY15_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_13905</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063632.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000033.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74096">
        <property type="protein sequence ID" value="KPL74096"/>
        <property type="gene ID" value="ADN00_13905"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL74096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="79" mass="7696" checksum="BC6CD5629498B67D" modified="2016-01-20" version="1">MQLSLLHPFPGLPAGEEVDAAGGWGLTTADFDPFPGLPAGEGVGAAGGWGLTTADFDPFPGFLAGEGVGAAGGWGVVDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XY19</accession>
    <name>A0A0P6XY19_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_00020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL80979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060908.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80979">
        <property type="protein sequence ID" value="KPL80979"/>
        <property type="gene ID" value="ADN00_00020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL80979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="239" mass="28107" checksum="5427E58B6B8AD668" modified="2016-01-20" version="1">MKDRSIFDTLLIIARPAAGKSEVIHYLKQTPLTDRINRFHIGQFSEIDDFPMLWTWFEEDDILEKMGKPRLHSDSDGYFLHPYLWDLLIERICLDYAKRKRDQAGEQSETILIEFSRGSQHGGYRSAFRHLSDAVLENLAILYIDVPFEESLRKNRRRFNPNRPDSILEHGLSDEKLVTLYEKIDWFELLDHPTHIVINGRRVPYVIMNNFDDVTTQGGEALGQRLQDALCQLWRLSME</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XY33</accession>
    <name>A0A0P6XY33_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_00190</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060939.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL81006">
        <property type="protein sequence ID" value="KPL81006"/>
        <property type="gene ID" value="ADN00_00190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL81006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="185" mass="21401" checksum="0B5C7C21086D5945" modified="2016-01-20" version="1">MIESSHTPKYLQKHQFQGQSNDCGPYCTAILLNYMQKTDIRGEQLGELMNKIAWKGLFPVIQRIKNWATFPWGVCEQFGAHGVKARWRLFTRPEILLSNLVRNIHTILIIGELRPKPWAHYLILSAYDAQKGWGFINSALSSPKVDWIPEAKFERMWRAYGRISISIEPVSPRPDEELPDSDPNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XYH1</accession>
    <name>A0A0P6XYH1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_07655</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062389.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78319">
        <property type="protein sequence ID" value="KPL78319"/>
        <property type="gene ID" value="ADN00_07655"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3361"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="252" mass="28451" checksum="79EF5037E822C0AF" modified="2016-01-20" version="1">MTVHLYLSLVPEALIASMLDPEEFGVYYAVGTEKKSRGQAIFFEIDPAYRNDFFAIEEGVQRCVPHEDGAPKASIYISVYRVLEHISMDAIQALYLTTQDGRTLKLETSSDIPAPTSRLHLYQEIAPVSPLVCSTLDPVKFYDLIVRNPASLLTLPAICFVDLRLGELAEDPMGGAVGDLPYDNIDHLREVLASMKTKHTKMVDRTHSATLAYRTIKTGVYVGNKEKLLFFPMPTQEELKAHHYNWWRSARM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y0G0</accession>
    <name>A0A0P6Y0G0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">CRISPR-associated endoribonuclease Cas2</fullName>
            <ecNumber evidence="9">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="primary">cas2</name>
        <name evidence="11" type="ORF">ADN00_06155</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homodimer, forms a heterotetramer with a Cas1 homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9 10">Belongs to the CRISPR-associated endoribonuclease Cas2 protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="9"/>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062088.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06155"/>
    <dbReference type="EnsemblBacteria" id="KPL78804">
        <property type="protein sequence ID" value="KPL78804"/>
        <property type="gene ID" value="ADN00_06155"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1732"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043571">
        <property type="term" value="P:maintenance of CRISPR repeat elements"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd09725">
        <property type="entry name" value="Cas2_I_II_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01471">
        <property type="entry name" value="Cas2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021127">
        <property type="entry name" value="CRISPR_associated_Cas2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019199">
        <property type="entry name" value="Virulence_VapD/CRISPR_Cas2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34405">
        <property type="entry name" value="PTHR34405"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09827">
        <property type="entry name" value="CRISPR_Cas2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF032582">
        <property type="entry name" value="Cas2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01573">
        <property type="entry name" value="cas2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9 10" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="5 9 10" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="6 9 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7 9 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4 9 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 9 10" id="KW-0540">Nuclease</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="9">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009959"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR032582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL78804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="96" mass="10977" checksum="4EFA43401F5985B0" modified="2016-01-20" version="1">MLVLITYDVNTETEAGKKRLRKVAKACQNYGQRVQNSVFECIIDPARFKQLQSNLEVLINKDVDSLRYYYLGDEENARVEHVGAKKPMDLKGTLIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y1P4</accession>
    <name>A0A0P6Y1P4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AP_endonuc_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_12715</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75504.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063395.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000027.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL75504">
        <property type="protein sequence ID" value="KPL75504"/>
        <property type="gene ID" value="ADN00_12715"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1236"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="1">
        <location>
            <begin position="41"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL75504.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="264" mass="29588" checksum="62011B464DF9BEA3" modified="2016-01-20" version="1">MSKIGMGLGSQQIADLAALTCQTDALELEDFLNPAEFDRLEPRLAEARAALRDYPGELLLSGPYIDLNPASPDALVQEACRQRFRQALDWAKQLGAREIIFCSTFIPIIYLEFYEADWARRSADFWSAFLDEVPGGVTISLCNTFEFDPRWLVWVAGQVNRPNFRLALDLGHFLVYARIGLEDWLRQTAPFLSTVYVHSNHGQVDEHLPPGEGLLSAEQVQMAARYAPAQARFVLKPFEKTALPASLAWLRRVLEAKSSTMGGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y2K7</accession>
    <name>A0A0P6Y2K7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">S-adenosylmethionine:tRNA ribosyltransferase-isomerase</fullName>
            <ecNumber evidence="5">2.4.99.17</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Queuosine biosynthesis protein QueA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">queA</name>
        <name evidence="6" type="ORF">ADN00_04730</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>7-aminomethyl-7-carbaguanosine(34) in tRNA + S-adenosyl-L-methionine = adenine + epoxyqueuosine(34) in tRNA + H(+) + L-methionine</text>
            <dbReference type="Rhea" id="RHEA:32155"/>
            <dbReference type="Rhea" id="RHEA-COMP:10342"/>
            <dbReference type="Rhea" id="RHEA-COMP:10346"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:82833"/>
            <dbReference type="ChEBI" id="CHEBI:82834"/>
            <dbReference type="EC" id="2.4.99.17"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">tRNA modification; tRNA-queuosine biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the QueA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.99.17" evidence="5"/>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061806.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04730"/>
    <dbReference type="EnsemblBacteria" id="KPL79160">
        <property type="protein sequence ID" value="KPL79160"/>
        <property type="gene ID" value="ADN00_04730"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.309"/>
    <dbReference type="UniPathway" id="UPA00392"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051075">
        <property type="term" value="F:S-adenosylmethionine:tRNA ribosyltransferase-isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00113">
        <property type="entry name" value="QueA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003699">
        <property type="entry name" value="QueA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042118">
        <property type="entry name" value="QueA_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042119">
        <property type="entry name" value="QueA_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036100">
        <property type="entry name" value="QueA_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30307">
        <property type="entry name" value="PTHR30307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02547">
        <property type="entry name" value="Queuosine_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF111337">
        <property type="entry name" value="SSF111337"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00113">
        <property type="entry name" value="queA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5 6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL79160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="339" mass="38060" checksum="D80E873363861925" modified="2016-01-20" version="1">MKTSDFDYDLPEEYIAQTPVEPRHASRLLVLHRASGELEHKQFWQIGEYLRPGDLLVINRTRVIPARLYAHKETGGKVELLLLRRVDELRWEALVGGKRMLPGKKVKLEDGLTAVIEAELDGARRMIRFEEAVEGHLERLGHMPLPPYIHERLDDPERYQTVYSQTPGSAAAPTAGLHFTPELIAQLEQQGVAFAGVTLHVGLDTFQPVHEDDPREHQIHTEWCELGEETAAAIRKTKQSGGRVIAVGTTSVRTLESAARHAKADEIVSPFAGPTDLFILPGYTFRAVDVMITNFHLPRSTLLMLVSAFAGRERVLAAYEIAKQHGYRFFSFGDAMLLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y2N8</accession>
    <name>A0A0P6Y2N8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Response regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_04910</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79188.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061836.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79188">
        <property type="protein sequence ID" value="KPL79188"/>
        <property type="gene ID" value="ADN00_04910"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1290">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002686">
        <property type="entry name" value="Transposase_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036515">
        <property type="entry name" value="Transposase_17_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01797">
        <property type="entry name" value="Y1_Tnp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143422">
        <property type="entry name" value="SSF143422"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="4"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="379"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="426"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="501"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="54"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL79188.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="711" mass="79032" checksum="DF62DC519B7B8C5F" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y332</accession>
    <name>A0A0P6Y332_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DZANK-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_11805</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063218.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11805"/>
    <dbReference type="EnsemblBacteria" id="KPL76035">
        <property type="protein sequence ID" value="KPL76035"/>
        <property type="gene ID" value="ADN00_11805"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025874">
        <property type="entry name" value="DZR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12773">
        <property type="entry name" value="DZR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="47"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="domain" description="DZANK-type" evidence="5">
        <location>
            <begin position="98"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF12773"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL76035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="168" mass="18594" checksum="237C9993FB9FC093" modified="2016-01-20" version="1">MKMDPAFFSNFLLVASAFAAAFAAALWLSLIIWTFRDIRRRSRDPLLRVLAALVVAVLFLPGIIIYLILRPPLTLDEEYQQALEEEALLQSIEDQALCPGCSRKVQSDWVACPNCHTRLKKACHNCGKAIELAWNICPYCGTSVPGARQGEDLLAPSSDYLSNPPSSI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y3G8</accession>
    <name>A0A0P6Y3G8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">50S ribosomal protein L6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rplF</name>
        <name evidence="7" type="ORF">ADN00_12530</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 5">This protein binds to the 23S rRNA, and is important in its secondary structure. It is located near the subunit interface in the base of the L7/L12 stalk, and near the tRNA binding site of the peptidyltransferase center.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the universal ribosomal protein uL6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063355.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12530"/>
    <dbReference type="EnsemblBacteria" id="KPL76153">
        <property type="protein sequence ID" value="KPL76153"/>
        <property type="gene ID" value="ADN00_12530"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3987"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.930.12">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01365_B">
        <property type="entry name" value="Ribosomal_L6_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000702">
        <property type="entry name" value="Ribosomal_L6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020040">
        <property type="entry name" value="Ribosomal_L6_a/b-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036789">
        <property type="entry name" value="Ribosomal_L6_a/b-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019906">
        <property type="entry name" value="Ribosomal_L6_bac-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655">
        <property type="entry name" value="PTHR11655"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11655:SF14">
        <property type="entry name" value="PTHR11655:SF14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00347">
        <property type="entry name" value="Ribosomal_L6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002162">
        <property type="entry name" value="Ribosomal_L6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00059">
        <property type="entry name" value="RIBOSOMALL6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56053">
        <property type="entry name" value="SSF56053"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03654">
        <property type="entry name" value="L6_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 5" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L6" evidence="6">
        <location>
            <begin position="11"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_L6" evidence="6">
        <location>
            <begin position="91"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL76153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="180" mass="19427" checksum="6638E9F25A19BCC9" modified="2016-01-20" version="1">MSRIGRMPVVIPAGVQVDIQGNAVSVKGPKGQLSYEHLPEVAVSVEDNILTVTRTNETPRARALHGTTRAVINNMVTGVSTGFEKSLEIQGVGYRAEMNGQNLVLYVGYSHPVVVEPKPGLSFDVDTKTRIVKVMGADKEVVGQAAAEVRKVRPPEPYHGKGIRYLGEQVRRKAGKTGKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y4L2</accession>
    <name>A0A0P6Y4L2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_11275</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063115.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76537">
        <property type="protein sequence ID" value="KPL76537"/>
        <property type="gene ID" value="ADN00_11275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="56"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL76537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="300" mass="32472" checksum="20462AD11364EFF4" modified="2016-01-20" version="1">MKSPRHWWLVGLAVSLMLLVVVALALAVAIILGINLVWWLPELRGSAALTQTVPSAVTATREPGSPTATQPARPTLMPSLTSTVLPATRTPTPVPTAGQAEPSTLGTPNPWQLIFEARFSDAASLVGGWEGIMAAANQSEFLLYRSRPALRLVFQEPVLVLSENIYTEDAPDRPDVQLETSLALEDNAAAQVELRCRVSGDAEGYALSLTRQEWRLVRLGPQEETVLGRGEPAEGFAAGGWGTFRLGCAGTTLFVWDDRGLIAEVEDDTYSDGASLLAFLPQEQAARSQVLIAWQRVFIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y7S0</accession>
    <name>A0A0P6Y7S0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_08765</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ABC transporter superfamily. Ycf16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000022">
        <property type="protein sequence ID" value="KPL77689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062635.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000022.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08765"/>
    <dbReference type="EnsemblBacteria" id="KPL77689">
        <property type="protein sequence ID" value="KPL77689"/>
        <property type="gene ID" value="ADN00_08765"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1471"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03217">
        <property type="entry name" value="ABC_FeS_Assembly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010230">
        <property type="entry name" value="FeS-cluster_ATPase_SufC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43204">
        <property type="entry name" value="PTHR43204"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="2"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006216"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL77689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="252" mass="27680" checksum="8E5A3D4D3F87E395" modified="2016-01-20" version="1">MLEIHDLHVEVRGEPILHGVDLAVPEGEVHALLGPNGSGKTSLMMTIMGFSGYKVTRGKILFMGQDITQASLTERARMGIAVAQQRPPTIPGVRLRQVVEYLTGSDEGHKSEVAALVEAVRVRPFMDREINAGLSGGEIRRSEMLQLLAMRPRFAMLDEIDSGVDVEALELIGAMANQLFSVEHGHPVRRRSGLIITHTGQVMEYVHADRAHIIMRGKISCTGNPGIIFDMVCDSGYEKCVECVNHIPEVHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YB82</accession>
    <name>A0A0P6YB82_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Aminoglycoside N(3)-acetyltransferase</fullName>
            <ecNumber evidence="5">2.3.1.81</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_04870</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a 2-deoxystreptamine antibiotic + acetyl-CoA = an N(3')-acetyl-2-deoxystreptamine antibiotic + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12665"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57921"/>
            <dbReference type="ChEBI" id="CHEBI:77452"/>
            <dbReference type="EC" id="2.3.1.81"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the antibiotic N-acetyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.81" evidence="5"/>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79180.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061828.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04870"/>
    <dbReference type="EnsemblBacteria" id="KPL79180">
        <property type="protein sequence ID" value="KPL79180"/>
        <property type="gene ID" value="ADN00_04870"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.341"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046353">
        <property type="term" value="F:aminoglycoside 3-N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003679">
        <property type="entry name" value="Amioglycoside_AcTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028345">
        <property type="entry name" value="Antibiotic_NAT-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11104">
        <property type="entry name" value="PTHR11104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02522">
        <property type="entry name" value="Antibiotic_NAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110710">
        <property type="entry name" value="SSF110710"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3 5" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5 6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU365031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL79180.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="272" mass="29966" checksum="5B8B9F74A764EAC3" modified="2016-01-20" version="1">MSEADVIARCDRGPVTRESLVHDLASLGVRPGMTLLVHSSLSALGWVCGGAVAVVLALEDALGEQGTLVMPTHSGDLSDPAEWAHPPVPADWIEVIRQSMPAYDPTLTPTRGMGAIVETFRRQPGVLRSAHPQLSFAARGPQAEKITANHSLHSSLGEQSPLARVYELDGFVLLLGVTHENNTSLHLCEHRANFPSRKIVRRGTPLMVNGQREWVWFEGVDENSDDFEQLGADYERETANVTVATTGYAQARLMRQRPLVDYGVQWMEKNRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YFP0</accession>
    <name>A0A0P6YFP0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">ADN00_00205</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the bacterial diacylglycerol kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060941.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00205"/>
    <dbReference type="EnsemblBacteria" id="KPL81008">
        <property type="protein sequence ID" value="KPL81008"/>
        <property type="gene ID" value="ADN00_00205"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3435"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14265">
        <property type="entry name" value="UDPK_IM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.3610">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000829">
        <property type="entry name" value="DAGK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036945">
        <property type="entry name" value="DAGK_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033717">
        <property type="entry name" value="UDPK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34299">
        <property type="entry name" value="PTHR34299"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01219">
        <property type="entry name" value="DAGK_prokar"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01069">
        <property type="entry name" value="DAGK_PROKAR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="10 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="29"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="53"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KPL81008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="125" mass="13475" checksum="D02095FC6C86A9E5" modified="2016-01-20" version="1">MDDFIISRIKSFKYAFSGLGYVIRTQKNAWIHALVSALVISLAFWLQCSSLEWAVLILSIGMVWMAEFINTALETAVDLATSKFHPLAKIGKDVGAAAVLIAASAAAVIGVLILGPRLIPFLLAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YFW3</accession>
    <name>A0A0P6YFW3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Response regulator SirA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_00820</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061050.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00820"/>
    <dbReference type="EnsemblBacteria" id="KPL81100">
        <property type="protein sequence ID" value="KPL81100"/>
        <property type="gene ID" value="ADN00_00820"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3562"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005144">
        <property type="entry name" value="ATP-cone_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006083">
        <property type="entry name" value="PRK/URK"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03477">
        <property type="entry name" value="ATP-cone"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00485">
        <property type="entry name" value="PRK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51161">
        <property type="entry name" value="ATP_CONE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-cone" evidence="4">
        <location>
            <begin position="5"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL81100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="446" mass="51511" checksum="7BF6CB26F51038E1" modified="2016-01-20" version="1">MSKLDFVIKRTGARVPFNPDRITNAIYRAAVAVGGRDRSTAENLTRQVVQMLEQTTPAGKDPTVEEIQDMVEKILIENGHARVAKAYILYREERARRRRETAKLASQPSENIPWSKIWKVLDWAVNHNLHTISTMNQRIGRGEFPQIVVESESAYQADLENAVELIFEKSSQLRLVIITGPSSSGKTTTTTKIAQRMSHAGFKLATLNVDNYFYDLAMHPKDEFGDYDFETPQALDLELINQHLLSLINGKKVLLPSYDFKTGTRRLEATPMQLKNNEIILIDSLHGLYREMTAGIPLENQFRLYLEPLLQMKDYNNQYIRWTDLRLIRRMLRDATHRAYDPRQTLEHWHYVRSSELRNIIPYINTTDYIINTAMPYEIALYRPKLLAHFTQWEHDYHGNPLRQDAYERAERVRGLLSSVIGVTDDSSVPGDSVLREFIGGSIYEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GKV6</accession>
    <name>A0A0N8GKV6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_17960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000044">
        <property type="protein sequence ID" value="KPL70762.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064424.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000044.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70762">
        <property type="protein sequence ID" value="KPL70762"/>
        <property type="gene ID" value="ADN00_17960"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70762.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="153" mass="16964" checksum="FC2EDFD10D37DE79" modified="2016-01-20" version="1">MIAGLFRFIWKIIETGMILLICTSLVFVGYKANQPMTVTGAPDGMTYVEFIQDRLDAAHTVKPSQCGWGMMLSLATLGPIYSVVYTEVAIHPDGFLDKVTAPDPDIPTGVAGAKWYEVPGIWWGVVERLSWTMLGKHTSFGCQFRPVMIPEIH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GKV7</accession>
    <name>A0A0N8GKV7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_18005</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000044">
        <property type="protein sequence ID" value="KPL70770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70770">
        <property type="protein sequence ID" value="KPL70770"/>
        <property type="gene ID" value="ADN00_18005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="184" mass="20590" checksum="A111164C2AC5AD9D" modified="2016-01-20" version="1">MDWNLARIRPTFKSHAIWIPNDVEIFWQRGGASLLADLLDAIGARVQRETSLPIAVHQPGVPRSPAEVCPGDLEFHHSFTPWSKKPYADRLPLNLEKAWRVDEFLGMQRAKSHCPGVSSTPCKIRMPLSTPFKKNRSYKYHIWSTSSGVKPKKRTAGATVSGGTANDEPIRTWFLASHCRTASG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GLD9</accession>
    <name>A0A0N8GLD9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_15515</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063941.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72226">
        <property type="protein sequence ID" value="KPL72226"/>
        <property type="gene ID" value="ADN00_15515"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="104" mass="11376" checksum="8C80A4917CA3EBA1" modified="2016-01-20" version="1">MALHEFNSFGLLFIKEDGITVNISAVKSTGTPIHRSYGEEFDEPIKLERPIMVSFAAEILPDGKTKTAFHEIGSNEYTPVAETIPQVGKALAKAFDLIRVAANI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GLP3</accession>
    <name>A0A0N8GLP3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_14780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000036">
        <property type="protein sequence ID" value="KPL73058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063805.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000036.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL73058">
        <property type="protein sequence ID" value="KPL73058"/>
        <property type="gene ID" value="ADN00_14780"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="41"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL73058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="78" mass="9184" checksum="4CB3DC90CDAFF45C" modified="2016-01-20" version="1">MPRIRCHYDDCAFLDEGYCSAAAVEIDPDNGCITYTPNDEPLTEDEWEEEEEELDEWEDLDLDEEDEEEDADETWSED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GM59</accession>
    <name>A0A0N8GM59_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Lon protease</fullName>
            <ecNumber evidence="5 6">3.4.21.53</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">ATP-dependent protease La</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">lon</name>
        <name evidence="14" type="ORF">ADN00_13795</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>Hydrolysis of proteins in presence of ATP.</text>
            <dbReference type="EC" id="3.4.21.53"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5 6">Homohexamer. Organized in a ring with a central cavity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="induction">
        <text evidence="5">By heat shock.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 6 9 10">Belongs to the peptidase S16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.53" evidence="5 6"/>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13795"/>
    <dbReference type="EnsemblBacteria" id="KPL74386">
        <property type="protein sequence ID" value="KPL74386"/>
        <property type="gene ID" value="ADN00_13795"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1336"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034605">
        <property type="term" value="P:cellular response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006515">
        <property type="term" value="P:protein quality control for misfolded or incompletely synthesized proteins"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01973">
        <property type="entry name" value="lon_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027543">
        <property type="entry name" value="Lon_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004815">
        <property type="entry name" value="Lon_bac/euk-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008269">
        <property type="entry name" value="Lon_proteolytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027065">
        <property type="entry name" value="Lon_Prtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003111">
        <property type="entry name" value="Lon_prtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046336">
        <property type="entry name" value="Lon_prtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008268">
        <property type="entry name" value="Peptidase_S16_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10046">
        <property type="entry name" value="PTHR10046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05362">
        <property type="entry name" value="Lon_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02190">
        <property type="entry name" value="LON_substr_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001174">
        <property type="entry name" value="Lon_proteas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00464">
        <property type="entry name" value="LON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00763">
        <property type="entry name" value="lon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51787">
        <property type="entry name" value="LON_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51786">
        <property type="entry name" value="LON_PROTEOLYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01046">
        <property type="entry name" value="LON_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword evidence="5 6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 5 6" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0720">Serine protease</keyword>
    <keyword evidence="4 5" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="Lon N-terminal" evidence="13">
        <location>
            <begin position="14"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="Lon proteolytic" evidence="12">
        <location>
            <begin position="596"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="776"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="776"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 7 9">
        <location>
            <position position="683"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 7 9">
        <location>
            <position position="726"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 8">
        <location>
            <begin position="360"/>
            <end position="367"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR001174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001174-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001174-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KPL74386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="804" mass="90364" checksum="1F35348C25238133" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GN44</accession>
    <name>A0A0N8GN44_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_09865</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09865"/>
    <dbReference type="EnsemblBacteria" id="KPL77066">
        <property type="protein sequence ID" value="KPL77066"/>
        <property type="gene ID" value="ADN00_09865"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2433"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0110165">
        <property type="term" value="C:cellular anatomical entity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002471">
        <property type="entry name" value="Pept_S9_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001375">
        <property type="entry name" value="Peptidase_S9"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00326">
        <property type="entry name" value="Peptidase_S9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00708">
        <property type="entry name" value="PRO_ENDOPEP_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S9" evidence="2">
        <location>
            <begin position="96"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="306" mass="34205" checksum="55BE81DBA99CB071" modified="2016-01-20" version="1">MPPSPTPTPHPMSIAGQRAASYPGSEIVIERELTAAYNHRRYYASYLSEGYKIYGLLTVPSDEMPPGGWPAIVFNHGYIPPDVYRTTERYVAYVNRLAQSGYIVFRIDYRGHDQSEGEAKGAYGDPGYLTDVLNAVAALQRFPDANPDKIGMWGHSMGGYLTLRAMVVSDQVKAGVIWAGVVASYPDMLYNWRHNDFARIPTPSSGARRWRDLWLETYGTPDENPEFWASVSANSYLADLSGPVQLHHGTADTDVPVAFSEGLYQQALAAGQNVELYTYEGDDHNLSGYFSLAMNRTIEFYDRYLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNV5</accession>
    <name>A0A0N8GNV5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">CTP synthase</fullName>
            <ecNumber evidence="9">6.3.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Cytidine 5'-triphosphate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">Cytidine triphosphate synthetase</fullName>
            <shortName evidence="9">CTP synthetase</shortName>
            <shortName evidence="9">CTPS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="9">UTP--ammonia ligase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">pyrG</name>
        <name evidence="12" type="ORF">ADN00_04700</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>ATP + H2O + L-glutamine + UTP = ADP + CTP + 2 H(+) + L-glutamate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:26426"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="6.3.4.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + NH4(+) + UTP = ADP + CTP + 2 H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:16597"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:46398"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>H2O + L-glutamine = L-glutamate + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:15889"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </reaction>
    </comment>
    <comment type="activity regulation">
        <text evidence="9">Allosterically activated by GTP, when glutamine is the substrate; GTP has no effect on the reaction when ammonia is the substrate. The allosteric effector GTP functions by stabilizing the protein conformation that binds the tetrahedral intermediate(s) formed during glutamine hydrolysis. Inhibited by the product CTP, via allosteric rather than competitive inhibition.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 9">Pyrimidine metabolism; CTP biosynthesis via de novo pathway; CTP from UDP: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Homotetramer.</text>
    </comment>
    <comment type="miscellaneous">
        <text evidence="9">CTPSs have evolved a hybrid strategy for distinguishing between UTP and CTP. The overlapping regions of the product feedback inhibitory and substrate sites recognize a common feature in both compounds, the triphosphate moiety. To differentiate isosteric substrate and product pyrimidine rings, an additional pocket far from the expected kinase/ligase catalytic site, specifically recognizes the cytosine and ribose portions of the product inhibitor.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the CTP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.2" evidence="9"/>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79154.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061800.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04700"/>
    <dbReference type="EnsemblBacteria" id="KPL79154">
        <property type="protein sequence ID" value="KPL79154"/>
        <property type="gene ID" value="ADN00_04700"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.302"/>
    <dbReference type="UniPathway" id="UPA00159">
        <property type="reaction ID" value="UER00277"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003883">
        <property type="term" value="F:CTP synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044210">
        <property type="term" value="P:'de novo' CTP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006541">
        <property type="term" value="P:glutamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03113">
        <property type="entry name" value="CTPS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01746">
        <property type="entry name" value="GATase1_CTP_Synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01227">
        <property type="entry name" value="PyrG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004468">
        <property type="entry name" value="CTP_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017456">
        <property type="entry name" value="CTP_synthase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017926">
        <property type="entry name" value="GATASE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033828">
        <property type="entry name" value="GATase1_CTP_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11550">
        <property type="entry name" value="PTHR11550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06418">
        <property type="entry name" value="CTP_synth_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00117">
        <property type="entry name" value="GATase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00337">
        <property type="entry name" value="PyrG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 9" id="KW-0315">Glutamine amidotransferase</keyword>
    <keyword evidence="4 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8 9" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CTP_synth_N" evidence="11">
        <location>
            <begin position="4"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="domain" description="GATase" evidence="10">
        <location>
            <begin position="304"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="region of interest" description="Amidoligase domain" evidence="9">
        <location>
            <begin position="1"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="L-glutamine binding" evidence="9">
        <location>
            <begin position="384"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile; for glutamine hydrolysis" evidence="9">
        <location>
            <position position="383"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="509"/>
        </location>
    </feature>
    <feature type="active site" evidence="9">
        <location>
            <position position="511"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="14"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="15"/>
            <end position="20"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="55"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="72"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="149"/>
            <end position="151"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <note>allosteric inhibitor</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="189"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="225"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="356"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="407"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="464"/>
        </location>
        <ligand>
            <name>L-glutamine</name>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000314"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF06418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KPL79154.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="550" mass="61654" checksum="2F56A3F73966A6CD" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNX5</accession>
    <name>A0A0N8GNX5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_03010</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000014">
        <property type="protein sequence ID" value="KPL79314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061480.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000014.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03010"/>
    <dbReference type="EnsemblBacteria" id="KPL79314">
        <property type="protein sequence ID" value="KPL79314"/>
        <property type="gene ID" value="ADN00_03010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2011"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016772">
        <property type="term" value="F:transferase activity, transferring phosphorus-containing groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="5">
        <location>
            <begin position="4"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="4">
        <location>
            <begin position="331"/>
            <end position="544"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL79314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="551" mass="60700" checksum="56107EC1AB462733" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNY5</accession>
    <name>A0A0N8GNY5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PlsC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_02910</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000013">
        <property type="protein sequence ID" value="KPL79394.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061457.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000013.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02910"/>
    <dbReference type="EnsemblBacteria" id="KPL79394">
        <property type="protein sequence ID" value="KPL79394"/>
        <property type="gene ID" value="ADN00_02910"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PlsC" evidence="1">
        <location>
            <begin position="37"/>
            <end position="155"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79394.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="237" mass="25755" checksum="D5297998AE757052" modified="2016-01-20" version="1">MFSSLWYQSGRILAKQYAQLAFHPNIEMRAPLADGAKILAANHPSTVDPVMMTTLTREPVSILISETLFKVPLLGTGLRWGGHITVQHSNGKACLEEALRRLNDGQTVGIFPEGAISPLKGGSPLKGGSHRAHTGVARLALASGAPVVPVGISIDRQRVWLTKTMVDGREETGTWYLSGPYAITVGEPMFFEGSVEDRARVREVADLIMQRINQLAYESELRAAEAAKTPARAWRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GP20</accession>
    <name>A0A0N8GP20_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">HAD family hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_02445</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000010">
        <property type="protein sequence ID" value="KPL79674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061368.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000010.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02445"/>
    <dbReference type="EnsemblBacteria" id="KPL79674">
        <property type="protein sequence ID" value="KPL79674"/>
        <property type="gene ID" value="ADN00_02445"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2707"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006357">
        <property type="entry name" value="HAD-SF_hydro_IIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13344">
        <property type="entry name" value="Hydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01460">
        <property type="entry name" value="HAD-SF-IIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="255" mass="27493" checksum="99DD2CA2A4699401" modified="2016-01-20" version="1">MGAKKNYLSDMDGVLIRGKEMVPGADLFIERLRKADAKFLVFTNNSLYTARDLSHNLKMTGLDVPENLIFTSAIATARFLQNQRPGGKAFVVGEVGLTAAIHEVGYIITEHDPDYVVLGETNYYNADAITKAIRLIAKGARFIATNPDTSGPTEAGIVPGCGAVAKLIEAATGIEPLYIGKPNPLMMRAALNYLGVHSEDTVMIGDRMDTDIITGVQSGMETILVLSGITSMAEVEKHPYQPTHILNSVADIVIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GPD5</accession>
    <name>A0A0N8GPD5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminotransferase</fullName>
            <ecNumber evidence="1">2.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_01770</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.-" evidence="1"/>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061241.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01770"/>
    <dbReference type="EnsemblBacteria" id="KPL80594">
        <property type="protein sequence ID" value="KPL80594"/>
        <property type="gene ID" value="ADN00_01770"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1116"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="3">
        <location>
            <begin position="43"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL80594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="402" mass="44025" checksum="C185F56E26C7E553" modified="2016-01-20" version="1">MSAAPSKPQTSTHSPRSYLSNRVTSLKPSGIRKFFDIVSTMDNVISLGIGEPDFTTPDPILEAGVRSLRKGETHYTSNHGLIELRRAIASHLKKLYGVEYDPQREIIVTVGGSEALYLTATGLLNPGDEMIIPTPCFVAYQAEAHMAGGVPVEVPSTMENNFALDPAAVRAAVTPRSRAILLGYPNNPTGAVAPREALTEVIEIAEEHDLIVVSDEIYDRLVYGDHQHVCVPTLPGAYHRTLLLGGFSKDYAMTGWRIGFIAGPPDIIEGLVRLHQYTIMSAPTTAQSAAITALQEGEPFVKQMVGEYDRRRRLMVEKFNAMGLPTFEPKGAFYTFPKVSVTGMTDEEFSEKLLHEERVAVVPGSAFGAGGEGFVRACYATAYDQIEEALERIARFVERHAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WMX1</accession>
    <name>A0A0P6WMX1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MFS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_18430</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18430"/>
    <dbReference type="EnsemblBacteria" id="KPL70167">
        <property type="protein sequence ID" value="KPL70167"/>
        <property type="gene ID" value="ADN00_18430"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024671">
        <property type="entry name" value="Atg22-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11700">
        <property type="entry name" value="ATG22"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="77"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="169"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="227"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="262"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="293"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="351"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="398"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="1"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL70167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="428" mass="46165" checksum="14B394E25CB9C510" modified="2016-01-20" version="1">MAKRARWAWYLYDFGNSAYAAVILLAVYSAYFKGTVVGGARGSWLWGLSIGIAMLIVTVLSPILGTIADFVAAKKRFLFVFTALSVTATSLLFFVEAGDILSGMIFFIIAEVGYRAAQVFYDALLPEISSQEDMAKVSGNGWAIGSAGGVVCLLIVLPLIILFKGALMVRVSMIITAVFYALSSIPLFLWVKEKAEPQALPAGENYLSLAYKRLSTTIKSTRQFRQFIRFIIAFLVYNDGILMILDFAAIIGAVLFGMNQQQLIILMIIVQVTSIGGAFLFGIIADRLGSKRAIVYSLVMMLVTVCSLVFIQSLVGFYLLAAVAGFALTGVQSVSRTMVGQISPEGKSGEFYGLFSVAGRTSSFIGPTVYGWVAVGAANYFHSVGQTLHVAEQSGQRAAVLSAAAFLVVGLILLFFVKDASRNKKETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WN89</accession>
    <name>A0A0P6WN89_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Imidazoleglycerol-phosphate dehydratase</fullName>
            <shortName evidence="5">IGPD</shortName>
            <ecNumber evidence="5 6">4.2.1.19</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hisB</name>
        <name evidence="7" type="ORF">ADN00_17440</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>D-erythro-1-(imidazol-4-yl)glycerol 3-phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + H2O</text>
            <dbReference type="Rhea" id="RHEA:11040"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:57766"/>
            <dbReference type="ChEBI" id="CHEBI:58278"/>
            <dbReference type="EC" id="4.2.1.19"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 5 6">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 6/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the imidazoleglycerol-phosphate dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.19" evidence="5 6"/>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71496.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17440"/>
    <dbReference type="EnsemblBacteria" id="KPL71496">
        <property type="protein sequence ID" value="KPL71496"/>
        <property type="gene ID" value="ADN00_17440"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.556"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00011"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004424">
        <property type="term" value="F:imidazoleglycerol-phosphate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07914">
        <property type="entry name" value="IGPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00076">
        <property type="entry name" value="HisB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038494">
        <property type="entry name" value="IGPD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000807">
        <property type="entry name" value="ImidazoleglycerolP_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020565">
        <property type="entry name" value="ImidazoleglycerP_deHydtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23133">
        <property type="entry name" value="PTHR23133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00475">
        <property type="entry name" value="IGPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00954">
        <property type="entry name" value="IGP_DEHYDRATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00955">
        <property type="entry name" value="IGP_DEHYDRATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5 6" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="4 5 6" id="KW-0456">Lyase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL71496.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="202" mass="22008" checksum="78EECB5C48C95384" modified="2016-01-20" version="1">MPSAPNRTAAITRSTRETSIRVSLDLDGSGKHQVSTGVPFFDHMLDQIAVHGLFDLQIAANGDVHIDPHHTMEDVGLTLGSAFREALGNKAGIIRMASFAVPMDESLARVTLDFSGRPYAVLHIQWSNPYLGGSIPTSLFEHFFESFAFEARCNLHIEVPYGRDDHHKAEAAFKALARALSAATRVDPRRAGSIPSSKGILM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WQ14</accession>
    <name>A0A0P6WQ14_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_15175</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72173">
        <property type="protein sequence ID" value="KPL72173"/>
        <property type="gene ID" value="ADN00_15175"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.737"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="66"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="193"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="236"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="263"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="291"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="2"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="162"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL72173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="313" mass="33016" checksum="94032D23D865B1B0" modified="2016-01-20" version="1">MAYLVLLVGVLAVSTASIFIRFAQSEVPSLVIATYRMALAGLLLAPAALWRGKQAQTSLEPAEKRQVLLAGVLLAFHFASWIASLELTSVVNSVVLVTTAPLWVAAASPVLLKEPVSGNAFIGLGLALVGGVLVGLSSICSITAGGFGCQEMGDFFQGKAALGNLLALMGAWFSAGYLVVGRRVRKKLHLMTYTFRVYGMAGLTLLVVTLFFGLVLNASSGTNVAELLFDYSPISFVWMILLALIPQLVGHTAFNWSLAYLPAAFVSVALLGEPVGSTILAILFLHESPTLLQFIGAGFILAGILLASRQTAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WSE4</accession>
    <name>A0A0P6WSE4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_15015</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000036">
        <property type="protein sequence ID" value="KPL73096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063849.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000036.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL73096">
        <property type="protein sequence ID" value="KPL73096"/>
        <property type="gene ID" value="ADN00_15015"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039968">
        <property type="entry name" value="YghO-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR41368">
        <property type="entry name" value="PTHR41368"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL73096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="375" mass="43455" checksum="A6AC84AC9061E388" modified="2016-01-20" version="1">MNFRKINTASSQDRQAFIHFPYQIYKDTPHWVPPLDSELHAAMNRSEHPFYRHSEADFFVVESEGQVLGRIQVIYNQNYCQHHQKQIAFVYYFECVDDPQVSQKLFDAAAVWARQRNLTGILGPKGMLRSAGHGLLQQGFEDDPAMGIPYNPQYYNALFEKYGFTKETDYFSGYLDTSMVLPDKLFEVAEKVKQRGNFWVKGFSSLAEMRKWIPELDSVHEQAFRTKANYYPSTPAEFTFMAKTMLQVMTPDLVKLIMKGDQIAGFILTYPDVSQALKRIKGKLFPFGWADVLMEQKRTRRLNINGLGILPEFQGLGANALLYAELDRTIRSANRFDRAEIVQVDERNFLSKSDMERMGVIWNKTHRSYTLQLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WY70</accession>
    <name>A0A0P6WY70_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nicotinamidase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_16790</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064207.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16790"/>
    <dbReference type="EnsemblBacteria" id="KPL71364">
        <property type="protein sequence ID" value="KPL71364"/>
        <property type="gene ID" value="ADN00_16790"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.417"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008936">
        <property type="term" value="F:nicotinamidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019365">
        <property type="term" value="P:pyridine nucleotide salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.850">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000868">
        <property type="entry name" value="Isochorismatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036380">
        <property type="entry name" value="Isochorismatase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044717">
        <property type="entry name" value="NIC1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47297">
        <property type="entry name" value="PTHR47297"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00857">
        <property type="entry name" value="Isochorismatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52499">
        <property type="entry name" value="SSF52499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Isochorismatase" evidence="1">
        <location>
            <begin position="39"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL71364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="236" mass="26068" checksum="54BFAD3ED41212FA" modified="2016-01-20" version="1">MKTSHLIDDSREYLEFVQNWVEALPAARMQDAKIHPASSALISVDVIKGFCSIGPLASPRVNTIVEPIARLMRRLWDLGLRHILLSQDTHEPDAVEFGAFPPHCVRGTEEAETVDAIQSLPFFDQMLLLEKNSIQSGLNTGLEQWISQHPEVDTFIVVGDCTDLCTYQLAMHLRLSANASQLQRRVIVPADCVQTYDMGVAAAAALGGVPHPGELLHHVFLHHMHLNGIEVVGSLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WY86</accession>
    <name>A0A0P6WY86_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_16965</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL71391">
        <property type="protein sequence ID" value="KPL71391"/>
        <property type="gene ID" value="ADN00_16965"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132697" evidence="3">
        <location>
            <begin position="29"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="44"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="202"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL71391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="235" mass="26519" checksum="4D74B6428436F747" modified="2016-01-20" version="1">MKSSQNRTPMPKRWLTTLFLALSAAAWAGCSPQNQSILPSPNRWSVYVPVLALVVIFFLFLTVALTLLALSVTIWIGWGRGWRPKDGFKQLLHTAYQARPESHTQPVRVRKASKEVAASAPAAAPSRAEVTQQIAVLKRAWRTRRLALEDLQRSQKQVILRQAVQHGQGTQAWLISQPPELETHSLDPILQRIFDSPEHPAFAQSLRAIQESKQELLEMQRQIRELLGQSRNGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WY91</accession>
    <name>A0A0P6WY91_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Flagellar hook-associated protein 2</fullName>
            <shortName evidence="5">HAP2</shortName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Flagellar cap protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_17025</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Required for morphogenesis and for the elongation of the flagellar filament by facilitating polymerization of the flagellin monomers at the tip of growing filament. Forms a capping structure, which prevents flagellin subunits (transported through the central channel of the flagellum) from leaking out without polymerization at the distal end.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 5">Homopentamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Secreted</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Bacterial flagellum</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the FliD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71400.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064251.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17025"/>
    <dbReference type="EnsemblBacteria" id="KPL71400">
        <property type="protein sequence ID" value="KPL71400"/>
        <property type="gene ID" value="ADN00_17025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009421">
        <property type="term" value="C:bacterial-type flagellum filament cap"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009424">
        <property type="term" value="C:bacterial-type flagellum hook"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007155">
        <property type="term" value="P:cell adhesion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010810">
        <property type="entry name" value="Flagellin_hook_IN_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040026">
        <property type="entry name" value="FliD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010809">
        <property type="entry name" value="FliD_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003481">
        <property type="entry name" value="FliD_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30288">
        <property type="entry name" value="PTHR30288"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07196">
        <property type="entry name" value="Flagellin_IN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07195">
        <property type="entry name" value="FliD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02465">
        <property type="entry name" value="FliD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0964">Secreted</keyword>
    <feature type="domain" description="FliD_N" evidence="6">
        <location>
            <begin position="14"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="domain" description="FliD_C" evidence="7">
        <location>
            <begin position="345"/>
            <end position="572"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU362066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF02465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL71400.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="583" mass="61900" checksum="6BABAA85463A41C1" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WYQ9</accession>
    <name>A0A0P6WYQ9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ANAPC5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_14320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000034">
        <property type="protein sequence ID" value="KPL73742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063713.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000034.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL73742">
        <property type="protein sequence ID" value="KPL73742"/>
        <property type="gene ID" value="ADN00_14320"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042802">
        <property type="term" value="F:identical protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026000">
        <property type="entry name" value="Apc5_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011717">
        <property type="entry name" value="TPR-4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12862">
        <property type="entry name" value="ANAPC5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07721">
        <property type="entry name" value="TPR_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ANAPC5" evidence="1">
        <location>
            <begin position="366"/>
            <end position="439"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL73742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="515" mass="58530" checksum="17C8C07038260ABD" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X229</accession>
    <name>A0A0P6X229_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Aminotran_1_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_11495</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063156.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11495"/>
    <dbReference type="EnsemblBacteria" id="KPL76571">
        <property type="protein sequence ID" value="KPL76571"/>
        <property type="gene ID" value="ADN00_11495"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004400">
        <property type="term" value="F:histidinol-phosphate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001917">
        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005861">
        <property type="entry name" value="HisP_aminotrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01141">
        <property type="entry name" value="hisC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00599">
        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="4">
        <location>
            <begin position="37"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL76571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="370" mass="41338" checksum="35E8D1FF8B1D3F3E" modified="2016-01-20" version="1">MDVTSKVSKAVKSAAAYNLEHFHQAWQRPELRRLMGNELLFPPSPRVISALVESLNQINYYPEDSGTHLRLREALAGYVGLAGRPDWITVGNGSMENIDMLPRTFIDEGDEILLPCPDYSPYTRRPQIFGAKVVDVTPDADFNYTLADFTAKVTPRTKMIILSRPNAPIGNMISRELLEDLCHLDCIVVVDEAYTEFSKQTVCDLVEKYDNLIISRTFSKAMGLGGIRLGFVVAQPAVIESINRVRVPINISLLTQVAAIAAVEDAEYIRANTLKVIENRESFIKSLRQIPGMQPIPSQGNFVMINCKKTRQPGKFFYDALLEAGYLVRCFDNARGLPGEGFFRVTIGTQQDIQGVLEVLHTQVVMSLTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X380</accession>
    <name>A0A0P6X380_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_09280</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77311">
        <property type="protein sequence ID" value="KPL77311"/>
        <property type="gene ID" value="ADN00_09280"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4090"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="2">
        <location>
            <begin position="16"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="Glycos_transf_1" evidence="1">
        <location>
            <begin position="189"/>
            <end position="338"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00534"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="368" mass="41409" checksum="1BC618A1D431EBED" modified="2016-01-20" version="1">MKIAMFGVKGVPVPAGAEYVVEEVGSRLAARGHEVVVYVRPHYTPREQHEYRGMRLVHLPSIPSKNFDAITHSFNAAMAVPGEKPDVVHIHSTGNSIFALPLRARGLSTVVTSHGLDWQRAKWGRLAKAYLRFTDFTTARFPNAATAVSQKMQHYYQDHFGRSVKYIPNGVKPVERVEPDEIHRLGLWGDDYILFAARLVPEKCAHHLIEAYCRIPYPTKKLVIAGDGSYGDLYAEKLKQSACDRIIFPGFVRGRLLEELLSNAYLYVLPSEIEGLSTGLLDAMNYENCVLVSDIEENLEVIADAGFSFRTNSVDDLSAKLTQLMLDEPLVREYRRKAGQSVRARYDWEKVTDQYLEIYSSLALSMAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X398</accession>
    <name>A0A0P6X398_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ABC transmembrane type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_09535</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062758.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77348">
        <property type="protein sequence ID" value="KPL77348"/>
        <property type="gene ID" value="ADN00_09535"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="164"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="203"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="231"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="259"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="69"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL77348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="291" mass="32908" checksum="5427B6C412C42F26" modified="2016-01-20" version="1">MISKSIRKRIETFQFLAPAIIVIAVVLVYPLLSTFRLSFFSYTIARGLRFIGLKNYLEILNDSTFYTALQNTFEFALIVILVEMTLGFIFANILNKDFPGRAIVRGLLMVPMLASPIVSGIMWRFMYNPDFGIINYFATQLNLPTQVWTGNPKTALLSCMIVDIWQYTPFVMLLLLAGLQSIPKEQYEAAEIDGAGAINKMRFITIPWLRPMILVVLLLRTMDSIKVFDQVYALTGGGPGISSLTLGVYAYTKGFRNFFLGYASAISWVLALITILISIFYIRSIKLPERE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X3A6</accession>
    <name>A0A0P6X3A6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09075</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062769.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77357">
        <property type="protein sequence ID" value="KPL77357"/>
        <property type="gene ID" value="ADN00_09075"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4049"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025495">
        <property type="entry name" value="DUF4386"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14329">
        <property type="entry name" value="DUF4386"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="49"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="138"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="170"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="230" mass="25248" checksum="39DE11E95F154808" modified="2016-01-20" version="1">MEENRKTAFMVGVLFIIGTVAGVLSLLVTGPVLNAPDYLVKIAEKQNQLILGSLLVLVMSFALAFVPVMMFPVFKKRNEIVALGYLIIRGALETVTYLGGAIGWLMLVALSQAYLQASPVNAASFEVLGNMLLKEAEISSQLTAIVFPLGALLFYYGLFQQRLIPRWLSVWGIIAVLMHLISTGLLGLFAMIDPMSPVQFALNFPIFLQEMVMAVWLIVKGFNPSASHRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X3Z2</accession>
    <name>A0A0P6X3Z2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_14145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063676.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000033.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74137">
        <property type="protein sequence ID" value="KPL74137"/>
        <property type="gene ID" value="ADN00_14145"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="198" mass="21129" checksum="96C439B7A28C0535" modified="2016-01-20" version="1">MSGCVHLAFAVSPAPGPSLAKSPLGGSGPAARQPLEELCFNPLAVELRTVKNEMERGFNLCCPDCRHVHFVVAEEIVEQLPYAYSGHRQPASARIQFSGAFARLFTPQTCRRVTPLIAALLAFTAGLAVGVHPLVSGWLALMVGMGGGLWISRALVEPLLRLVMAERMPIFLIPCPHCQQTAAVATDGKAFFLGAPGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X419</accession>
    <name>A0A0P6X419_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7 9">50S ribosomal protein L23</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rplW</name>
        <name evidence="10" type="ORF">ADN00_12590</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">One of the early assembly proteins it binds 23S rRNA. One of the proteins that surrounds the polypeptide exit tunnel on the outside of the ribosome. Forms the main docking site for trigger factor binding to the ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Part of the 50S ribosomal subunit. Contacts protein L29, and trigger factor when it is bound to the ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the universal ribosomal protein uL23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063368.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12590"/>
    <dbReference type="EnsemblBacteria" id="KPL76165">
        <property type="protein sequence ID" value="KPL76165"/>
        <property type="gene ID" value="ADN00_12590"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3999"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01369_B">
        <property type="entry name" value="Ribosomal_L23_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012678">
        <property type="entry name" value="Ribosomal_L23/L15e_core_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001014">
        <property type="entry name" value="Ribosomal_L23/L25_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013025">
        <property type="entry name" value="Ribosomal_L25/23"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11620">
        <property type="entry name" value="PTHR11620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00276">
        <property type="entry name" value="Ribosomal_L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54189">
        <property type="entry name" value="SSF54189"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00050">
        <property type="entry name" value="RIBOSOMAL_L23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7 8" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 7 8" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 7 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7 9" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021203"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL76165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="100" mass="11395" checksum="BBEC20E4A1789757" modified="2016-01-20" version="1">MNTIYDVLRRPLVTEKSNYQVSKLHQYVFEVAPNATRSMVKDAVSKLFDVKVLRVNIVNVPAKSTRRARSRRMAIRQSAYKKAIVTLAPEDSIAIFEGVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X6S8</accession>
    <name>A0A0P6X6S8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNase_PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05890</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062040.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05890"/>
    <dbReference type="EnsemblBacteria" id="KPL78765">
        <property type="protein sequence ID" value="KPL78765"/>
        <property type="gene ID" value="ADN00_05890"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1654"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001247">
        <property type="entry name" value="ExoRNase_PH_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027408">
        <property type="entry name" value="PNPase/RNase_PH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01138">
        <property type="entry name" value="RNase_PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RNase_PH" evidence="1">
        <location>
            <begin position="15"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="86" mass="9816" checksum="AA38CAB8791E1FB9" modified="2016-01-20" version="1">MPEQKMRQDGRRPDELRPLCFTTDYVDYPHGSVLVDMGKTRVLCNVCVEEKVPDWMAGRGVGWLTAEYSMLPQSMPVNILIQVGYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X6X3</accession>
    <name>A0A0P6X6X3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_06210</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062097.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06210"/>
    <dbReference type="EnsemblBacteria" id="KPL78811">
        <property type="protein sequence ID" value="KPL78811"/>
        <property type="gene ID" value="ADN00_06210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="251"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="304"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="354"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="429"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="658"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="709"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="756"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="288"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="695"/>
            <end position="785"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL78811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="796" mass="87147" checksum="FBB4131DBCE361E1" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X705</accession>
    <name>A0A0P6X705_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">M20_dimer domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_06370</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062125.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06370"/>
    <dbReference type="EnsemblBacteria" id="KPL78838">
        <property type="protein sequence ID" value="KPL78838"/>
        <property type="gene ID" value="ADN00_06370"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001261">
        <property type="entry name" value="ArgE/DapE_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00758">
        <property type="entry name" value="ARGE_DAPE_CPG2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="2">
        <location>
            <begin position="189"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="426" mass="47803" checksum="2FA2994086B3D747" modified="2016-01-20" version="1">MDLFDAEWEQQGKELFRDLIQFDSVNPPGNEAPVANYLAKRFAEAGITCQILEKSTGRCNLVARLSSESKRPPIALISHLDVVPADSEQWTYPPFSATERDGFIWGRGTLDTKQLTAMQAMAFLALKKYELNRDVIFVASADEEAGSHFGMEWLVKEMPDLQHSGLIISEGGGFPIVSNGRTYMLVAAGEKGVCQVTLRAEGDTGHASCPPLNQAIYHLAEALRRLTTHHFEEKYSQLTRHFLIETGLNPCEKQMDRSVLSSLMQYQLSDTLTINYLQVGDATNVIPKLTEAQIEFRLLPGTSRGEIEQLLNEKLVDLPVQWTITTFEEGYESDTDSEILRLFEENARLFGFQGDLLPFLALGRTDGRFLCAEGASIFGFSPVLLDDSYEEALKRVHNNDERISDQSFRFGLKVFVKSLLDLCVEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7A8</accession>
    <name>A0A0P6X7A8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_18345</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18345"/>
    <dbReference type="EnsemblBacteria" id="KPL70025">
        <property type="protein sequence ID" value="KPL70025"/>
        <property type="gene ID" value="ADN00_18345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="238" mass="26991" checksum="3A137B9BDB913A8D" modified="2016-01-20" version="1">MECHVCGLLRKKEVDFDEIDTQYKAGWESPSAHIQQTGATDMELSESYIAHLLKELRINSFLGLRILDFGAGRGNMAAALRHAGAEVVCIEPYGMEELERKGFKVFSSIPDLPEDLLFDGVVCLDVIEHLFDPWEDFKHLTNDLAPNGWIFVSTPNSASLNSKLSGENWRERKNPGHIFLFNPNNLSQTLEIAGYSGIHRLKWNIVYHRNLLIQLKDFVLLQSGLDGELRFLAYRGSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7X0</accession>
    <name>A0A0P6X7X0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_07875</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000020">
        <property type="protein sequence ID" value="KPL78085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062441.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000020.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78085">
        <property type="protein sequence ID" value="KPL78085"/>
        <property type="gene ID" value="ADN00_07875"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132909" evidence="2">
        <location>
            <begin position="30"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="162" mass="17911" checksum="EA03350559227625" modified="2016-01-20" version="1">MFQVSKLKTFGRVALLVLLLATTMGPWFADSHPATEESCSRPLVWLGDGYCACLIPLKDYVEGALGHDVMWLLCLPPALPVLSTLLLLLFGERQWLWICHLSAWGIAGIYAFLWFGGAWYAHRGVLILWGAGLGGVVAVALLIGEMLIARLQFSMNHREELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X896</accession>
    <name>A0A0P6X896_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glutaredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_07485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062359.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07485"/>
    <dbReference type="EnsemblBacteria" id="KPL78295">
        <property type="protein sequence ID" value="KPL78295"/>
        <property type="gene ID" value="ADN00_07485"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097573">
        <property type="term" value="F:glutathione oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011911">
        <property type="entry name" value="GlrX_YruB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002109">
        <property type="entry name" value="Glutaredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00462">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02196">
        <property type="entry name" value="GlrX_YruB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glutaredoxin" evidence="1">
        <location>
            <begin position="7"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="81" mass="9249" checksum="46E684BC6E9F7AF2" modified="2016-01-20" version="1">MDSQPRVIIFTTPTCRYCSTAKQYLQQKKIRFKEVDVTRDAAAARDMVRRSGQQGVPVIDIGGKIIVGFDRSKIDRYLNLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X8P2</accession>
    <name>A0A0P6X8P2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">30S ribosomal protein S2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsB</name>
        <name evidence="8" type="ORF">ADN00_03055</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uS2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000014">
        <property type="protein sequence ID" value="KPL79323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061489.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000014.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03055"/>
    <dbReference type="EnsemblBacteria" id="KPL79323">
        <property type="protein sequence ID" value="KPL79323"/>
        <property type="gene ID" value="ADN00_03055"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2022"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01425">
        <property type="entry name" value="RPS2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00291_B">
        <property type="entry name" value="Ribosomal_S2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001865">
        <property type="entry name" value="Ribosomal_S2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005706">
        <property type="entry name" value="Ribosomal_S2_bac/mit/plastid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018130">
        <property type="entry name" value="Ribosomal_S2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023591">
        <property type="entry name" value="Ribosomal_S2_flav_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12534">
        <property type="entry name" value="PTHR12534"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00318">
        <property type="entry name" value="Ribosomal_S2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00395">
        <property type="entry name" value="RIBOSOMALS2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52313">
        <property type="entry name" value="SSF52313"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01011">
        <property type="entry name" value="rpsB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00962">
        <property type="entry name" value="RIBOSOMAL_S2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00963">
        <property type="entry name" value="RIBOSOMAL_S2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="256"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL79323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="289" mass="32680" checksum="5D47061876B5861F" modified="2016-01-20" version="1">MASVVSMKALLESGVHFGHRTNKWDPKMKPFIFTERNGIHIIDLQQTVKLLNDAYNVVRDTVANGGSVLFVGTKRQAQETIAEEAIRSGSPYVTERWLGGTLTNWITIQQRIRELERLERMQETGEINQLTKKEGLLIQREINRLKLRLSGIRNMRNLPDLIFVVDISREMTAIHEANLKGIPVIALVDTNCDPTNIDYVIPSNDDAIRAIKLLVGKIADAVIEGRSMRKEEDMEAEEMAEQPKAEVARPRRRLVTEDMEMDDDDLLGESTLAKLGSREGGMEEGEDEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9W1</accession>
    <name>A0A0P6X9W1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_06400</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062131.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06400"/>
    <dbReference type="EnsemblBacteria" id="KPL78844">
        <property type="protein sequence ID" value="KPL78844"/>
        <property type="gene ID" value="ADN00_06400"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1783"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="17"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="50"/>
            <end position="57"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL78844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="322" mass="36195" checksum="145410C0936003D3" modified="2016-01-20" version="1">MNTNLVEVKNLKKYFPVNQTNLFSTQKQFVKAVDDISFAIQSGETMGFVGESGCGKSTVGRTILRLIEPTEGQVLFEGQDILKLPPNDLREMRKEMQIIFQDPYASLDPRKTVKEIVGEAFHIHKIGSSKEIESQVKELLLLVGMGPDQINRYPHEFSGGQRQRIGIARALALHPKFVVCDEPVSALDVSIQAQVVNLMKDLQQKLGLTYLFISHDLRIVKHICDRISVMYLGALVEIADKADLYKNPLHPYTQALLSAIPTTNPNAKRQRIILEGDVPSPMNPPSGCRFHTRCPEAQEICKLKAPELRDLDTNHMVACHMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XA10</accession>
    <name>A0A0P6XA10_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_11485</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76569.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063154.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11485"/>
    <dbReference type="EnsemblBacteria" id="KPL76569">
        <property type="protein sequence ID" value="KPL76569"/>
        <property type="gene ID" value="ADN00_11485"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.998"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032688">
        <property type="entry name" value="ABC2_membrane_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019196">
        <property type="entry name" value="ABC_transp_unknown"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12679">
        <property type="entry name" value="ABC2_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09822">
        <property type="entry name" value="ABC_transp_aux"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="53"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="100"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="133"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="161"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="216"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="254"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="912"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="domain" description="ABC_transp_aux" evidence="7">
        <location>
            <begin position="275"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="domain" description="ABC_transp_aux" evidence="7">
        <location>
            <begin position="435"/>
            <end position="687"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF09822"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL76569.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="954" mass="104896" checksum="8A0CF2426B170349" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XA40</accession>
    <name>A0A0P6XA40_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Polyphosphate kinase</fullName>
            <ecNumber evidence="6 7">2.7.4.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">ATP-polyphosphate phosphotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Polyphosphoric acid kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">ppk</name>
        <name evidence="12" type="ORF">ADN00_17365</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6 7">Catalyzes the reversible transfer of the terminal phosphate of ATP to form a long-chain polyphosphate (polyP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>[phosphate](n) + ATP = [phosphate](n+1) + ADP</text>
            <dbReference type="Rhea" id="RHEA:19573"/>
            <dbReference type="Rhea" id="RHEA-COMP:9859"/>
            <dbReference type="Rhea" id="RHEA-COMP:14280"/>
            <dbReference type="ChEBI" id="CHEBI:16838"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="PTM">
        <text evidence="6 7">An intermediate of this reaction is the autophosphorylated ppk in which a phosphate is covalently linked to a histidine residue through a N-P bond.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6 7">Belongs to the polyphosphate kinase 1 (PPK1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.1" evidence="6 7"/>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71452.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064315.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17365"/>
    <dbReference type="EnsemblBacteria" id="KPL71452">
        <property type="protein sequence ID" value="KPL71452"/>
        <property type="gene ID" value="ADN00_17365"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.537"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009358">
        <property type="term" value="C:polyphosphate kinase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008976">
        <property type="term" value="F:polyphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006799">
        <property type="term" value="P:polyphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1840.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00347">
        <property type="entry name" value="Polyphosphate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003414">
        <property type="entry name" value="PP_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041108">
        <property type="entry name" value="PP_kinase_C_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024953">
        <property type="entry name" value="PP_kinase_middle"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036830">
        <property type="entry name" value="PP_kinase_middle_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025200">
        <property type="entry name" value="PPK_C_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025198">
        <property type="entry name" value="PPK_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036832">
        <property type="entry name" value="PPK_N_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30218">
        <property type="entry name" value="PTHR30218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02503">
        <property type="entry name" value="PP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13090">
        <property type="entry name" value="PP_kinase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17941">
        <property type="entry name" value="PP_kinase_C_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13089">
        <property type="entry name" value="PP_kinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015589">
        <property type="entry name" value="PP_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140356">
        <property type="entry name" value="SSF140356"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03705">
        <property type="entry name" value="poly_P_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6 12" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1 6 7" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PP_kinase_N" evidence="9">
        <location>
            <begin position="16"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="PP_kinase" evidence="8">
        <location>
            <begin position="131"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="PP_kinase_C_1" evidence="11">
        <location>
            <begin position="349"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="domain" description="PP_kinase_C" evidence="10">
        <location>
            <begin position="522"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="active site" description="Phosphohistidine intermediate" evidence="6">
        <location>
            <position position="454"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="54"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="393"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="424"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="487"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="583"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="611"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00347"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02503"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF17941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KPL71452.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="710" mass="81881" checksum="374472C2DCFD4FB5" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XA47</accession>
    <name>A0A0P6XA47_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_17420</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064324.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17420"/>
    <dbReference type="EnsemblBacteria" id="KPL71461">
        <property type="protein sequence ID" value="KPL71461"/>
        <property type="gene ID" value="ADN00_17420"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.552"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004792">
        <property type="entry name" value="BaiN-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023166">
        <property type="entry name" value="HI0933-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42887">
        <property type="entry name" value="PTHR42887"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00275">
        <property type="entry name" value="TIGR00275"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL71461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="416" mass="45053" checksum="F405322912387958" modified="2016-01-20" version="1">MVSDLDRKVDLLIIGGGPAGFFGALACKAARPASSVLILEKSAKPLSKVLVSGGGRCNLTNATFDPAQLVHFYPRGGKALRGAFSRFAPQDTMQWFESHGVALKTEADGRVFPVSDDARTIVQCLLSEAERAGVELRTHSPVEALHCGQHGFQVRTSGTEILHARTLLLATGGDRNSFALAAACGHTLIPPVPSLFSFAIRDTRLEGLAGLSAENAEIRLAGTRLQTTGPFIITHTGISGPAVLKLSAWAARELNTAQYQMDIFINFLPGFNPETLYPRLLEIREQNPDQTAYPQALGLSLPRRLWARLLAAADIAAGTLWRNCSNTRLYQLAQQITRAEFHLQGRGEFKDEFVTAGGVDLNEVDFRAMQSKLVPGLFFAGEVLNIDGLTGGFNFQNAWTTSYIAGQAVADYLNRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XA77</accession>
    <name>A0A0P6XA77_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_02425</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000010">
        <property type="protein sequence ID" value="KPL79670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79670">
        <property type="protein sequence ID" value="KPL79670"/>
        <property type="gene ID" value="ADN00_02425"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="86" mass="9738" checksum="4538FD65FABEC040" modified="2016-01-20" version="1">MGLILLSEEEVDAPPSFWAKGNEQARLVSRMTAKKTNREIGFFIFISTRFLVRFTQQPNQTEPSESGRAFCLFLQATSMEETCSGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAB5</accession>
    <name>A0A0P6XAB5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_16645</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064166.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16645"/>
    <dbReference type="EnsemblBacteria" id="KPL72097">
        <property type="protein sequence ID" value="KPL72097"/>
        <property type="gene ID" value="ADN00_16645"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008963">
        <property type="term" value="F:phospho-N-acetylmuramoyl-pentapeptide-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000715">
        <property type="entry name" value="Glycosyl_transferase_4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22926">
        <property type="entry name" value="PTHR22926"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00953">
        <property type="entry name" value="Glycos_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="56"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="81"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="148"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="172"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="195"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="219"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="251"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="302"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="328"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL72097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="358" mass="39447" checksum="D1AC5F84CEB536EC" modified="2016-01-20" version="1">MEFSLKLFLNILQVLFISVVISLATSFFSLKTTPRLGLMDIPGSAPHKQHSRPTPLGGGISLVMALVITAFLFGFWRQSELRSLLLPALIIFAFALWDDKSGLGALPKLVGQIAASICMIWLGTRVRVLEYSGFFWGDFFSLKVALDWGITIFWMVGITNAFNLVDSMDGLVVGLSSWAAGFFLLVLISSGQTELALFTAALFGCLIALTFFNSAPAKMFLGDSGAQTIGFLMAGIAILYTPQGAFQESSWFTPIMFLAVPIFDTALVTFSRIRRGDKFYISHLDHTYHRLIKLGLDSNQGVMLMHLTGLILQAVAITALFLQPLYANLIFLLVLIVGAVLILVLDRYSFWPRINPPD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAG9</accession>
    <name>A0A0P6XAG9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_04405</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061741.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79109">
        <property type="protein sequence ID" value="KPL79109"/>
        <property type="gene ID" value="ADN00_04405"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="5"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="257"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="37"/>
            <end position="44"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL79109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="510" mass="55660" checksum="0B5F7BC1D23FC4F6" modified="2016-01-20" version="1">MPELLRLEKIQKTFPGVLANDNVDLTIQRGEIHALLGENGSGKTTLMNCVFGVYRPTRGQIYWKGQPMEIHQAHDAIALGMGMVHQHFMLIPQLTVAENVILGLKSPREPFLNLEAVARQIFETGQRFHLNVDPHAPVWSLPVGAQQRVEILKVLYRQAELLILDEPTAVLTPGEVEELFAVLKELARAGLSIIFITHKLEEVMAICDQVTVLRNGRVVASSPVDQTTPQDLARSMVGREVALNLQKPPAQPGEVVLSVQNLRALGSRGLPALNNISFEIRAGEILGIAGVDGNGQTELGDVIAGLRRAASGRVTIAGQDTLNRPPREILDLNFAYIPPDRQRTGLLMELPIAENLVAKTITRPPFSRRGFLQQAEINRFAAQAVSEYEIKTPQASLPVRLLSGGNQQKVVLAREVSRRPRLLIASQPTRGLDIGASEYVHRQMLAARAAGAAILLISTDLEEILSLSDRIAVLYEGQIMGILATADAPIHKIGEMMAGVFRQPGGQIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAJ3</accession>
    <name>A0A0P6XAJ3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_15265</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72189.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15265"/>
    <dbReference type="EnsemblBacteria" id="KPL72189">
        <property type="protein sequence ID" value="KPL72189"/>
        <property type="gene ID" value="ADN00_15265"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72189.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="286" mass="30612" checksum="7BE029CDFBDD902B" modified="2016-01-20" version="1">MVAGLFFTNMDEVIGAQVKFDLEQGVPLTRSMITDAKEGSYAAFEIPRGMVAISIPIDELTSLSYGLQPRDHINIIGTIQLVDLDTDFQTRLPNYTASVISPGPTDCNECAGDSLSAIISTGGAGSTQGRTELDPVFQQPVYVIPSEAQRPRMVSQTIVQDAIVLWVGDFPETGQLTTAAAHPTPTPLPEGQAPVEGQAVQAAPLPTRITLIVTPQDAVTLRYMLLSEADLALVLRGAGDTDRVATEAVTLQFIMDQYNFPYPAKLPYGLDNVTSITDLLAPAPLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAL6</accession>
    <name>A0A0P6XAL6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Hydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_15385</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HypE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72207.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063921.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15385"/>
    <dbReference type="EnsemblBacteria" id="KPL72207">
        <property type="protein sequence ID" value="KPL72207"/>
        <property type="gene ID" value="ADN00_15385"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.779"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02197">
        <property type="entry name" value="HypE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.650.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011854">
        <property type="entry name" value="HypE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010918">
        <property type="entry name" value="PurM-like_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036676">
        <property type="entry name" value="PurM-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016188">
        <property type="entry name" value="PurM-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036921">
        <property type="entry name" value="PurM-like_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30303">
        <property type="entry name" value="PTHR30303"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00586">
        <property type="entry name" value="AIRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02769">
        <property type="entry name" value="AIRS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005644">
        <property type="entry name" value="Hdrgns_mtr_HypE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55326">
        <property type="entry name" value="SSF55326"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56042">
        <property type="entry name" value="SSF56042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02124">
        <property type="entry name" value="hypE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AIRS" evidence="2">
        <location>
            <begin position="72"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="AIRS_C" evidence="3">
        <location>
            <begin position="183"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006243"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00586"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL72207.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="357" mass="37423" checksum="E90F1D36B1CEEDE5" modified="2016-01-20" version="1">MTTIQSFEGPSCPLPLQHNETIVMGHGSGGKMTQDLIKNVFYPYFNSTPLSEGNDFARAALPESANLKGRLSISTDCHSVSPIQFPGGDIGKLAVCGTVNDMCMSGALPLYLTAGFILEEGFPIATLQQIVASMAAAAQEAGVAIVAGDTKVVEHGKADGVYITTSGIGWIPESRTIGGQYAQPGDVVIISGSIGDHGMAVLTARGDLGFEADIQSDVAPLNLMIANLLQAAPNTHVLRDPTRGGLATTLNEIVQQSGVGMILNETEIPVRPVVRTACEMLGFDPLYVANEGKLIAILPAAEAQAGLQAIQDSPYGDQAAIIGEVVAQPLKRVLLRTEMGTTRILDTLAGEMLPRIC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XB18</accession>
    <name>A0A0P6XB18_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">D-aminoacyl-tRNA deacylase</fullName>
            <shortName evidence="1">DTD</shortName>
            <ecNumber evidence="1">3.1.1.96</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Gly-tRNA(Ala) deacylase</fullName>
            <ecNumber evidence="1">3.1.1.-</ecNumber>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">dtd</name>
        <name evidence="2" type="ORF">ADN00_03260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">An aminoacyl-tRNA editing enzyme that deacylates mischarged D-aminoacyl-tRNAs. Also deacylates mischarged glycyl-tRNA(Ala), protecting cells against glycine mischarging by AlaRS. Acts via tRNA-based rather than protein-based catalysis; rejects L-amino acids rather than detecting D-amino acids in the active site. By recycling D-aminoacyl-tRNA to D-amino acids and free tRNA molecules, this enzyme counteracts the toxicity associated with the formation of D-aminoacyl-tRNA entities in vivo and helps enforce protein L-homochirality.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a D-aminoacyl-tRNA + H2O = a D-alpha-amino acid + a tRNA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13953"/>
            <dbReference type="Rhea" id="RHEA-COMP:10123"/>
            <dbReference type="Rhea" id="RHEA-COMP:10124"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:59871"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:79333"/>
            <dbReference type="EC" id="3.1.1.96"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>glycyl-tRNA(Ala) + H2O = glycine + H(+) + tRNA(Ala)</text>
            <dbReference type="Rhea" id="RHEA:53744"/>
            <dbReference type="Rhea" id="RHEA-COMP:9657"/>
            <dbReference type="Rhea" id="RHEA-COMP:13640"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78522"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="1">A Gly-cisPro motif from one monomer fits into the active site of the other monomer to allow specific chiral rejection of L-amino acids.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the DTD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.96" evidence="1"/>
    <dbReference type="EC" id="3.1.1.-" evidence="1"/>
    <dbReference type="EMBL" id="LGCL01000014">
        <property type="protein sequence ID" value="KPL79356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061525.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000014.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03260"/>
    <dbReference type="EnsemblBacteria" id="KPL79356">
        <property type="protein sequence ID" value="KPL79356"/>
        <property type="gene ID" value="ADN00_03260"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2063"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051499">
        <property type="term" value="F:D-aminoacyl-tRNA deacylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106026">
        <property type="term" value="F:Gly-tRNA(Ala) hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043908">
        <property type="term" value="F:Ser(Gly)-tRNA(Ala) hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019478">
        <property type="term" value="P:D-amino acid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00563">
        <property type="entry name" value="Dtyr_deacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00518">
        <property type="entry name" value="Deacylase_Dtd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003732">
        <property type="entry name" value="Daa-tRNA_deacyls_DTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023509">
        <property type="entry name" value="DTD-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10472">
        <property type="entry name" value="PTHR10472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02580">
        <property type="entry name" value="Tyr_Deacylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69500">
        <property type="entry name" value="SSF69500"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00256">
        <property type="entry name" value="TIGR00256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="1" id="KW-0820">tRNA-binding</keyword>
    <feature type="short sequence motif" description="Gly-cisPro motif, important for rejection of L-amino acids" evidence="1">
        <location>
            <begin position="137"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="145" mass="15546" checksum="448AFF125BE7B0F4" modified="2016-01-20" version="1">MRAVVQRVKQGSVTIDGAVRASIGQGLVILLGVGPEDGPENASALARKIAMMRIFSDEQGKMNLSVLDVQGEVIVVSQFTLYADTRKGHRPSFVKAAPPDLASPLVDQFAALLREQGVPTQTGEFGADMLVKIENDGPVTIWLEM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBG8</accession>
    <name>A0A0P6XBG8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_16320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064106.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72046">
        <property type="protein sequence ID" value="KPL72046"/>
        <property type="gene ID" value="ADN00_16320"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132970" evidence="1">
        <location>
            <begin position="30"/>
            <end position="453"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="453" mass="49251" checksum="0F98124A4BA1EC57" modified="2016-01-20" version="1">MMPKKLNFVLVIFVAVAMILTACAPSAPAAPAASENQPAEAGQPAQPAEKVTLRVLVHQNPPMVEFMENFNAQFTEKYPNITVDMSVVNANDLATVTQTRLTANDVDVIDIFGFANGVQPYMKNVDKPNWQQLIEAGLLLDISDQPFLKNYDESANMDAGSFDGKVYAINLGRVSYSGIYYNKDLFAANNVTVPTTWSELVTACETFKAAGIPCMTAGGKDGWPIFVGAYGLIGSIYPDQAALVEGLWNGSIKWNDEKSMVMWERMKVYAQEMMEEGASGIAGDAAPGRFASGAVAMFSGGTWYASAIEAAEPAFEWGYIPFPGSDNPEDNKYLFGKYDQGWAVAANTPNKDASLLYLTEFSDPANYQAFVDAVGFIPTQPTATLNTQIGQEVAPYLQNFKVGYEQYWVNVKGAGQFANPWASYFVPFGTYDDAKELADKVQADLQSGLDAAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBK0</accession>
    <name>A0A0P6XBK0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_16610</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064160.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72092">
        <property type="protein sequence ID" value="KPL72092"/>
        <property type="gene ID" value="ADN00_16610"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="268" mass="29912" checksum="F93DB6B39773365C" modified="2016-01-20" version="1">MLHENPLMANIDVNHWRNMQALLLQSAKGKRRIVLIHENGELLKFVHSERAEIVKSVTRVDDPQMVAKKVYEDNPGLADFVFVVERNAADRYFYQVQDAWSATEDLDVYVHRMFALLDAYPDGIVTYPGSARTNLGLQWKFGAKYEDVQTAVENFVSVNTSMVLAVFDGDDLWGSLVMSFDDQKRITNLTTLDPTELTNTKGMKACAEEIVDWVSKTYSTCSLGVFIDLADAKAFIASDEKLAALKAAALKGNLLVDPMPKSLAKLLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBR8</accession>
    <name>A0A0P6XBR8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Aminoglycoside N(3)-acetyltransferase</fullName>
            <ecNumber evidence="5">2.3.1.81</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_02340</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a 2-deoxystreptamine antibiotic + acetyl-CoA = an N(3')-acetyl-2-deoxystreptamine antibiotic + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:12665"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:57921"/>
            <dbReference type="ChEBI" id="CHEBI:77452"/>
            <dbReference type="EC" id="2.3.1.81"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the antibiotic N-acetyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.81" evidence="5"/>
    <dbReference type="EMBL" id="LGCL01000010">
        <property type="protein sequence ID" value="KPL79657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061351.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000010.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02340"/>
    <dbReference type="EnsemblBacteria" id="KPL79657">
        <property type="protein sequence ID" value="KPL79657"/>
        <property type="gene ID" value="ADN00_02340"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046353">
        <property type="term" value="F:aminoglycoside 3-N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046677">
        <property type="term" value="P:response to antibiotic"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003679">
        <property type="entry name" value="Amioglycoside_AcTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028345">
        <property type="entry name" value="Antibiotic_NAT-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11104">
        <property type="entry name" value="PTHR11104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02522">
        <property type="entry name" value="Antibiotic_NAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110710">
        <property type="entry name" value="SSF110710"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="3 5" id="KW-0046">Antibiotic resistance</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU365031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL79657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="270" mass="29407" checksum="3383CC55671D58B9" modified="2016-01-20" version="1">MLSFRDLVSGFRKLNLDPQQPVMVHASFSSFGEDVRGGAETLLGALLATSNALIAPTFTYKTMVIPSDGPPDNGITYGSGKESNLMAEFYRSTMPADRLMGIFAETLRLHPNAERSSHPILSFSAINLDDALQAQTLQDPLAPIRVLAQKQAWIMLIGVDHTVNTAIHFAEKLAGRKQFLRWALTAQGVVECPGFPGCSNGFQDAEEWLSGITQSVKIGEALIEVLPLQPMLNLLTEKIKEDPLALLCNSSNCERCSAVWSGVTKMVENS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XC30</accession>
    <name>A0A0P6XC30_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ABC transmembrane type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_09530</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062757.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77347">
        <property type="protein sequence ID" value="KPL77347"/>
        <property type="gene ID" value="ADN00_09530"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="71"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="108"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="141"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="184"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="246"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="72"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL77347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="277" mass="30706" checksum="4AE2586CBBE7AC40" modified="2016-01-20" version="1">MQRKFTKLIGDTLSYTFLACALVFFMFPIFWMLMTSLKQPQDTFAIPPIWIFKPTLQNYIKTFVEGAYYKYLFVSLRVTTVSIFVATVISTLAAYATARFRFRGKTGLLMSLLVFYTIPGIAYAIPLYMLYGQLKIQDTPLGLMIIFTALTIPFSTWVLHGYFVSIPKDLEDSAMVDGCTKLGALTRVVLPLAAPGVASTAILTFITTWNSFLYPAILAGSRTKTLPVAVAAFITDTRIEWGQACAVASAVILPVLLLIMFAQRFIVMGLTSGAVKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XCC0</accession>
    <name>A0A0P6XCC0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase</fullName>
            <ecNumber evidence="2">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_08380</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="2"/>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77883.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062534.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08380"/>
    <dbReference type="EnsemblBacteria" id="KPL77883">
        <property type="protein sequence ID" value="KPL77883"/>
        <property type="gene ID" value="ADN00_08380"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="52"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="93"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="132"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="165"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="250"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="517"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="8">
        <location>
            <begin position="539"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="7">
        <location>
            <begin position="872"/>
            <end position="1089"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL77883.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="1098" mass="120720" checksum="EF3AA226A94425FF" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XCY5</accession>
    <name>A0A0P6XCY5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DNA_pol3_delta domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01535</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80553.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061199.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01535"/>
    <dbReference type="EnsemblBacteria" id="KPL80553">
        <property type="protein sequence ID" value="KPL80553"/>
        <property type="gene ID" value="ADN00_01535"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009360">
        <property type="term" value="C:DNA polymerase III complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008921">
        <property type="entry name" value="DNA_pol3_clamp-load_cplx_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010372">
        <property type="entry name" value="DNA_pol3_delta_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005790">
        <property type="entry name" value="DNA_polIII_delta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06144">
        <property type="entry name" value="DNA_pol3_delta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48019">
        <property type="entry name" value="SSF48019"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01128">
        <property type="entry name" value="holA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_pol3_delta" evidence="1">
        <location>
            <begin position="11"/>
            <end position="196"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80553.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="343" mass="38043" checksum="A6A491E77D922163" modified="2016-01-20" version="1">MAQQSQPVVCILHGDDTYAMAQKVNEAAQSLGDPGMADLNTARLDGRSVSEDEIHMAASSLPFLAERRLVILTHPLARLTSPAARERFTRLLDSLPPTTAFYLLIEDTYRNKKVGGEWTVVWDVLKDSHWLMKWVASTAQSVAVSEFRLPTGAGMRAWVQQKAVELGGTFHPAAAQALADQIGNDTRVATLEIEKLLTYVDFARAVEEDDVLLLTSAAHQASVFDLVDALGQGDERAAMRLLQTLLEQEDPFSVFGMIVRQFRLLLQAREVMDEGGGLDLIQKELGAARFVAEKMASQARRFSMKRLESVYHRLLDVDEAVKTSQMDFDLALDLLVSEVNRQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDF0</accession>
    <name>A0A0P6XDF0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosomal silencing factor RsfS</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rsfS</name>
        <name evidence="3" type="ORF">ADN00_01140</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Interacts with ribosomal protein L14 (rplN).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the Iojap/RsfS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000003">
        <property type="protein sequence ID" value="KPL80828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061128.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01140"/>
    <dbReference type="EnsemblBacteria" id="KPL80828">
        <property type="protein sequence ID" value="KPL80828"/>
        <property type="gene ID" value="ADN00_01140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042256">
        <property type="term" value="P:mature ribosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090071">
        <property type="term" value="P:negative regulation of ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01477">
        <property type="entry name" value="Iojap_RsfS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004394">
        <property type="entry name" value="Iojap/RsfS/C7orf30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21043">
        <property type="entry name" value="PTHR21043"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00090">
        <property type="entry name" value="rsfS_iojap_ybeB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="2" id="KW-0810">Translation regulation</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL80828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="105" mass="11783" checksum="E33C6AB9FAA8D966" modified="2016-01-20" version="1">MITALEEKKAEDILLLDIRGIADFADFFIICSGTSDRMLGALADAAIECARVDHGIKTRVRGLPSSGWLIADLGDIVIHFFSPDQREYYDLEELWKDGKVLVRLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XER9</accession>
    <name>A0A0P6XER9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78678.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061942.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78678">
        <property type="protein sequence ID" value="KPL78678"/>
        <property type="gene ID" value="ADN00_05350"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="216"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="255"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="294"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="325"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="362"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="388"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78678.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="686" mass="78620" checksum="32192B73F89FC654" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XG63</accession>
    <name>A0A0P6XG63_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_18535</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064532.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18535"/>
    <dbReference type="EnsemblBacteria" id="KPL70054">
        <property type="protein sequence ID" value="KPL70054"/>
        <property type="gene ID" value="ADN00_18535"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029401">
        <property type="entry name" value="Nudix_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14803">
        <property type="entry name" value="Nudix_N_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="3">
        <location>
            <begin position="35"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL70054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="168" mass="18799" checksum="0D71DA1AB7129986" modified="2016-01-20" version="1">MDACHYCCLCGAELELKWLEERAREVCPRCGWVHYPQLKVSAAALVESHGKLLLVQRAEEPWKGCWYLPAGYVEADESPMAAAEREAFEETGLRVAVTNLFNIYYFDDDPRGNGILIVYRCEIIGGTLAGNAEVMMCGYFSPEDLPEPLTGAGHLHAVHDWLAHQNLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGD2</accession>
    <name>A0A0P6XGD2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH gntR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05885</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062039.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05885"/>
    <dbReference type="EnsemblBacteria" id="KPL78764">
        <property type="protein sequence ID" value="KPL78764"/>
        <property type="gene ID" value="ADN00_05885"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028978">
        <property type="entry name" value="Chorismate_lyase_/UTRA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011663">
        <property type="entry name" value="UTRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07702">
        <property type="entry name" value="UTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00866">
        <property type="entry name" value="UTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64288">
        <property type="entry name" value="SSF64288"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="1">
        <location>
            <begin position="10"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="244" mass="27882" checksum="148CDA19418E8A79" modified="2016-01-20" version="1">MKKIVRSSYLPMYIQISDIIREAIQNGELCENDRVWSEREIMDRFDVSRNTAQSAIDELVKNGLLTRIQGKGTFVSNWRVNIGLQSLVSFSEATRIKGKTPSSKIISFTTEEPSKSVAQKLEIEPNAAVYKLERLRLADDLPMMHEVSYLPVSLFPDLTRFDFSQESLFAVLEKEYQAQIGWQKQIIHPLISTAYEAELLSVSAGVPLIETEGITYLEDNTPIEVNRLIYRSDLYELSVISKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGT6</accession>
    <name>A0A0P6XGT6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_03405</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061559.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03405"/>
    <dbReference type="EnsemblBacteria" id="KPL78956">
        <property type="protein sequence ID" value="KPL78956"/>
        <property type="gene ID" value="ADN00_03405"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025098">
        <property type="entry name" value="DUF4013"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13197">
        <property type="entry name" value="DUF4013"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="179"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="211" mass="22230" checksum="01642B00980145B6" modified="2016-01-20" version="1">MEFGLPFTYAFQDSDWFKKIALAGAVSLIPIIGQIFLLGWGLEIARRVINNDPNPLPDLDFGNQLGLGFKAWVVSLVYAIPMFILTIPSSLISAFAGSNGDDTMLTVMAVLSICTGLVSVIYGLLMGFVLPAAYGRVAMTNTIGAGLKFGEVFAMVKKAPMAFLIALLGSIVAGLIAPLGLIACVVGVVVTGAFSVAVLGHFYGQAYKQAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGZ1</accession>
    <name>A0A0P6XGZ1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_03950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79047">
        <property type="protein sequence ID" value="KPL79047"/>
        <property type="gene ID" value="ADN00_03950"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022453">
        <property type="entry name" value="Znf_MqsA-type"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03831">
        <property type="entry name" value="YgiT_finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="68" mass="7669" checksum="7148C2EC241402D6" modified="2016-01-20" version="1">MTWLGEEMVMVPDFPAWVCDVCGRREYDQLAMARLSMLLNSEAGKPVSRPRTIHPVKGHKSARPNVSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XH58</accession>
    <name>A0A0P6XH58_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_04520</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061765.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04520"/>
    <dbReference type="EnsemblBacteria" id="KPL79129">
        <property type="protein sequence ID" value="KPL79129"/>
        <property type="gene ID" value="ADN00_04520"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002197">
        <property type="entry name" value="HTH_Fis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002078">
        <property type="entry name" value="Sigma_54_int"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02954">
        <property type="entry name" value="HTH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00158">
        <property type="entry name" value="Sigma54_activat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01590">
        <property type="entry name" value="HTHFIS"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50045">
        <property type="entry name" value="SIGMA54_INTERACT_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="PAS" evidence="6">
        <location>
            <begin position="212"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma-54 factor interaction" evidence="5">
        <location>
            <begin position="340"/>
            <end position="569"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50045"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL79129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="656" mass="73693" checksum="76885655A2C50079" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XIE9</accession>
    <name>A0A0P6XIE9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">Homoserine kinase</fullName>
            <shortName evidence="11">HK</shortName>
            <shortName evidence="11">HSK</shortName>
            <ecNumber evidence="4 11">2.7.1.39</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">thrB</name>
        <name evidence="14" type="ORF">ADN00_17730</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="11">Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + L-homoserine = ADP + H(+) + O-phospho-L-homoserine</text>
            <dbReference type="Rhea" id="RHEA:13985"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57476"/>
            <dbReference type="ChEBI" id="CHEBI:57590"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.39"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 4/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the GHMP kinase family. Homoserine kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.39" evidence="4 11"/>
    <dbReference type="EMBL" id="LGCL01000043">
        <property type="protein sequence ID" value="KPL70886.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064386.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000043.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17730"/>
    <dbReference type="EnsemblBacteria" id="KPL70886">
        <property type="protein sequence ID" value="KPL70886"/>
        <property type="gene ID" value="ADN00_17730"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2137"/>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00064"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004413">
        <property type="term" value="F:homoserine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00384">
        <property type="entry name" value="Homoser_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006203">
        <property type="entry name" value="GHMP_knse_ATP-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000870">
        <property type="entry name" value="Homoserine_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08544">
        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000676">
        <property type="entry name" value="Homoser_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="SSF55060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00191">
        <property type="entry name" value="thrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00627">
        <property type="entry name" value="GHMP_KINASES_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0791">Threonine biosynthesis</keyword>
    <keyword evidence="6 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP_kinases_N" evidence="12">
        <location>
            <begin position="83"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP_kinases_C" evidence="13">
        <location>
            <begin position="205"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <begin position="91"/>
            <end position="101"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00017858"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KPL70886.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="302" mass="30988" checksum="72DA57550F2F7CC1" modified="2016-01-20" version="1">MSLQTVKVSVPATTANLGPGFDCLGVALDLWNEVTFSLQGSGIHVEVQGEGAGLVPASEQNLVAQSYLQFCALNGLPAPSGLRVVCRNHIPLGSGMGSSAAAVVAGMLGASQLTGVGASPDSILEYADQIEGHPDNAAAAIYGGLVIIAAGEQRLLTRRYDLPELHVAVALGEIDLPTRAARAALPKNVSLADAVFNISRTALVVEALRSGDLELLGQVMQDRLHQPYRLPLMPGAAQVIEAALQAGAQAAAISGAGPSLIAFTRQPAGAVANAMQRAYQDAGTPARAFALRTTNLGAQIES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XIG1</accession>
    <name>A0A0P6XIG1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">M20_dimer domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_17885</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000043">
        <property type="protein sequence ID" value="KPL70904.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17885"/>
    <dbReference type="EnsemblBacteria" id="KPL70904">
        <property type="protein sequence ID" value="KPL70904"/>
        <property type="gene ID" value="ADN00_17885"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036264">
        <property type="entry name" value="Bact_exopeptidase_dim_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011650">
        <property type="entry name" value="Peptidase_M20_dimer"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07687">
        <property type="entry name" value="M20_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55031">
        <property type="entry name" value="SSF55031"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="M20_dimer" evidence="1">
        <location>
            <begin position="171"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70904.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="394" mass="42053" checksum="B7E107A1CA31CE14" modified="2016-01-20" version="1">MGLSVEPQNEAVDLLRRLVQAPGLSGQEAAAAAVVEAQMLRLGFDRVWRDEVGNVIGERRGDLPGPRLVFEAHMDVVEMGRREDWSVDPFGAALRDGKVYGRGAADTKGSLAALITALGSLERAQIRGSLFAVGSVGEETLEGAGLRHALEALQPQGVVVGEPTGCRLAMGQKGRARIVFWARGRAAHSSTPQLGENALIKAAEIVRRVESLPLPEDAWLGRGVMAPLFIQSEPLPPLSSTLPHACQVVYDRRLVLGETEESVLGEYRRALADVPGWELAVEEVSFETYTGRVLRAPDFHPGWHMPPDSAWVRGAVSALEGAGIDPRPHAVPYCTNASTAAGEMGLPALIFGPGDIEQAHVPDEYLAVEDLLRGVEGYRALALGLPLALASQGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XIP4</accession>
    <name>A0A0P6XIP4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HTH lacI-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_13540</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063555.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000031.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13540"/>
    <dbReference type="EnsemblBacteria" id="KPL74853">
        <property type="protein sequence ID" value="KPL74853"/>
        <property type="gene ID" value="ADN00_13540"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1201"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00036">
        <property type="entry name" value="HTHLACI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="8"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL74853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="339" mass="37371" checksum="4A3CF0B4145936F9" modified="2016-01-20" version="1">MDQEKQSVTIQDVARTAGVSVSTVSRALNGKSDVAKETRGRILSIIEEMGFTTNLAARSMRSQKKNLIGLIMPDIAYPFAIEVMKGVNRAIAESEFDLLVYTTGNVRKSGRAHHERKYVSLLTKSITDGVIIVAPVVGEFNTDEPIVSIDPVMSNPTNPAVHATNYQGSMEAMEYLIGLGHKRIGYIGGRVELESSNRRLLGYRDSLKKANIPIDEKLIASGDFTTETGISCSRMLLSLPNRPTAIFASNDQMALGVFQVAEEMGLRIPEDLSLVGFDNIPESKYLGLTTVDQFISEMGYMGTQMLIKIINGIPLDEQTYRMQTRLVIRNSCRAIDARD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XIS1</accession>
    <name>A0A0P6XIS1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">ADN00_01860</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell membrane</location>
            <topology evidence="3">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the peptidase M50B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000007">
        <property type="protein sequence ID" value="KPL80040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061263.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000007.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80040">
        <property type="protein sequence ID" value="KPL80040"/>
        <property type="gene ID" value="ADN00_01860"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2298"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06158">
        <property type="entry name" value="S2P-M50_like_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044537">
        <property type="entry name" value="S2P-M50-like"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11 14" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="9"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="129"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="172"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KPL80040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="213" mass="23688" checksum="9E064B9574CC15C6" modified="2016-01-20" version="1">MFGLSVPTLLSRIITLVIAFTIHEFSHAWTANQFGDDTPRLNGRLTLNPAAHLDLMGTLMLLMAGFGWARPVPINPYALRRRSPSAVMWVSFAGPLSNLLLAILAAIPLRLGLVPLRYPTGMFPTLYSFLWDFISINLLLLLFNLIPLAPLDGDKMAEYLFPPRWARALETIRPYGPIILLAIVFVLPIIGIDLFAWILTPALYALRGLLIGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XIU5</accession>
    <name>A0A0P6XIU5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_12680</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063389.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000027.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12680"/>
    <dbReference type="EnsemblBacteria" id="KPL75499">
        <property type="protein sequence ID" value="KPL75499"/>
        <property type="gene ID" value="ADN00_12680"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1229"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="6"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="265"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL75499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="507" mass="56294" checksum="89EC57AF0974AD4F" modified="2016-01-20" version="1">MKPPILEMKNITKEFPGVKALSDVSFAVTEGEIHCLVGENGAGKSTLMKVLSGVYPHGEYSGEITFNGQVQKFSRINDSEKVGIAIIYQELALIPELTVYENIFLGNEIRKGMMVDWNETIKRATEMLKKVKLDINPAVKVKDLGVGQQQLVEIAKALSREVKLLILDEPTSALNEDDSQNLLQLLRDLKEQGVTCIMISHKLKEVIQIADTVTVLRDGKTICTLDAHKGEVNENVLIKHMVGREIENIYPPKEHQVFDEVVFEARNWNAYNPVLGRKVVKNANFKVKKGEIVGFAGLMGSGRTELALSLFGNPEGYHVEGEVYLKGKKQHFTHPQQAINAGIAYLSEDRKAKGLVLIQDVKENISLSNLAEIAKRGVVDKNAEIVVANEYKNSLNIKTPTVAQKVQNLSGGNQQKVCLGKWLFVKPDVLILDEPTRGIDVGAKYEIYTIMTQLVRQGMSIIMISSELPEILGMSDRIYVVSSGKIAGEMPVHEATQEKIMELATEY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKF9</accession>
    <name>A0A0P6XKF9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_12700</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063392.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000027.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL75502">
        <property type="protein sequence ID" value="KPL75502"/>
        <property type="gene ID" value="ADN00_12700"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1233"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="73"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="106"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="155"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="225"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="289"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="314"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="340"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="375"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL75502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="539" mass="60969" checksum="C5D26770D4A28081" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKT7</accession>
    <name>A0A0P6XKT7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">NADH dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_15470</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063936.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15470"/>
    <dbReference type="EnsemblBacteria" id="KPL72221">
        <property type="protein sequence ID" value="KPL72221"/>
        <property type="gene ID" value="ADN00_15470"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="122" mass="13136" checksum="6A540C64BD634068" modified="2016-01-20" version="1">MNKIKSLEDLKKIREEALHKREVRAAAGQIEIVVGMGTVGIAAGARETLKAILDFIEKENLTGVTVRQAGNIGLDSFEPVVQVTVGAEPKVTYGKVSPESAQRIMQEHIVGGSVVKDLMLNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKV1</accession>
    <name>A0A0P6XKV1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_15640</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72248.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72248">
        <property type="protein sequence ID" value="KPL72248"/>
        <property type="gene ID" value="ADN00_15640"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021375">
        <property type="entry name" value="DUF2997"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11211">
        <property type="entry name" value="DUF2997"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72248.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="64" mass="7143" checksum="033FB365C615E48C" modified="2016-01-20" version="1">MMNKPHKIEIQITPEGKVIGEVKGVSGPQCGPLTKWLEEIGSVQVDRSTPDYHKNSDQNLTVKR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XMA2</accession>
    <name>A0A0P6XMA2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_18485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064524.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70046">
        <property type="protein sequence ID" value="KPL70046"/>
        <property type="gene ID" value="ADN00_18485"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="140"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="140" mass="15861" checksum="4C8BB8A966E356ED" modified="2016-01-20" version="1">MTPIAYSIFQTEDYDEAAAFWQRTPYIGLSSADKCEAISIFLARNPGFSFTARDGDTLVGTVLLGHDGRRGYMYHLAVAAEYRGQGIARELIRLGLEALRGAGIEKCHLFVYTDNQNALEFYRHEGWQQREELVIFSMNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XMK4</accession>
    <name>A0A0P6XMK4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Formimidoyltransferase-cyclodeaminase</fullName>
            <ecNumber evidence="6">2.1.2.5</ecNumber>
            <ecNumber evidence="7">4.3.1.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="19">Formiminotransferase-cyclodeaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">ADN00_19190</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="22 23" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="22 23">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Folate-dependent enzyme, that displays both transferase and deaminase activity. Serves to channel one-carbon units from formiminoglutamate to the folate pool.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid degradation; L-histidine degradation into L-glutamate; L-glutamate from N-formimidoyl-L-glutamate (transferase route): step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="18">Homooctamer, including four polyglutamate binding sites. The subunits are arranged as a tetramer of dimers, and form a planar ring-shaped structure.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
            <location evidence="1">Centrosome</location>
            <location evidence="1">Centriole</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">In the C-terminal section; belongs to the cyclodeaminase/cyclohydrolase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">In the N-terminal section; belongs to the formiminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.5" evidence="6"/>
    <dbReference type="EC" id="4.3.1.4" evidence="7"/>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064651.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_19190"/>
    <dbReference type="EnsemblBacteria" id="KPL70156">
        <property type="protein sequence ID" value="KPL70156"/>
        <property type="gene ID" value="ADN00_19190"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00379">
        <property type="reaction ID" value="UER00555"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005814">
        <property type="term" value="C:centriole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005542">
        <property type="term" value="F:folic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030412">
        <property type="term" value="F:formimidoyltetrahydrofolate cyclodeaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030409">
        <property type="term" value="F:glutamate formimidoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019556">
        <property type="term" value="P:histidine catabolic process to glutamate and formamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019557">
        <property type="term" value="P:histidine catabolic process to glutamate and formate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035999">
        <property type="term" value="P:tetrahydrofolate interconversion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.680">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.670">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.990.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007044">
        <property type="entry name" value="Cyclodeamin/CycHdrlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013802">
        <property type="entry name" value="Formiminotransferase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037070">
        <property type="entry name" value="Formiminotransferase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004227">
        <property type="entry name" value="Formiminotransferase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012886">
        <property type="entry name" value="Formiminotransferase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037064">
        <property type="entry name" value="Formiminotransferase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022384">
        <property type="entry name" value="FormiminoTrfase_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036178">
        <property type="entry name" value="Formintransfe-cycloase-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02971">
        <property type="entry name" value="FTCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04961">
        <property type="entry name" value="FTCD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07837">
        <property type="entry name" value="FTCD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01221">
        <property type="entry name" value="FTCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01222">
        <property type="entry name" value="FTCD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101262">
        <property type="entry name" value="SSF101262"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55116">
        <property type="entry name" value="SSF55116"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02024">
        <property type="entry name" value="FtcD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="14" id="KW-0206">Cytoskeleton</keyword>
    <keyword evidence="12" id="KW-0290">Folate-binding</keyword>
    <keyword evidence="13" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="11" id="KW-0369">Histidine metabolism</keyword>
    <keyword evidence="15" id="KW-0456">Lyase</keyword>
    <keyword evidence="16" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FTCD_N" evidence="21">
        <location>
            <begin position="4"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="FTCD" evidence="20">
        <location>
            <begin position="182"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00008297"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00010825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012252"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00012998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00017787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00025506"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00025915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="ARBA" id="ARBA00030029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="SMART" id="SM01221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="SMART" id="SM01222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KPL70156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="510" mass="55114" checksum="94BA1FB50988C283" modified="2016-01-20" version="1">MARQIVECIPNFSEARRPEIVQAIAASVSSIQGVQILDQHSDLDHNRTVITFVGPKEAVEAAAYQSIETAARLIDLNQHTGEHPRIGAADVVPFVPISGVTMEECIEMAHRLAKRVASQLNIPVYLYEEAAQNPDRKNLENIRKGQYEGLKEEILTNPNRKPDYGPAELGPAGATVIGARNPLIAFNVYLTSDDVEIAQKIARTIRFSTGGLRFVKAMGVLVDGRAQVSMNLTHFRKTPLAQVVEMIRREAQRYGVAIHHSELVGLIPQEALEDAAVWYLQLDQFEKNQILENRLADLAIESASVAAPEPSFIDELASASPTPGGGSASAYAGAMAAALVCMVARVTLGKKKYAEVEAEMLQTIETASALQAHLQECVAQDSAAFEAFIHARRLPKDTPEQEAIRLQAISVATYQAASVPLDVAENSLKVLKLAQAVARKGNLNAVSDAASAAALAQAAIIGAGHNVRINLIGLESEEQAAGMLQRLQEIETAQIEIHSTIPTIIKERSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XNZ3</accession>
    <name>A0A0P6XNZ3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GNAT family acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10360</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10360"/>
    <dbReference type="EnsemblBacteria" id="KPL76974">
        <property type="protein sequence ID" value="KPL76974"/>
        <property type="gene ID" value="ADN00_10360"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="6"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="143" mass="15729" checksum="15DE01A03BC02086" modified="2016-01-20" version="1">MNMPITRLPAATDAFMQALARLMPQLSNAPVPTREHIQAVIESPASQILLAEEDGQIAGMLTLVIYATPAGTHAWIEDVVVDTAFRGRGLGAELTREAIQLAREAGAKAVSLTSRPSREAANRLYQKMGFQRWETNLYRLLLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XPV4</accession>
    <name>A0A0P6XPV4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">D-ribose pyranase</fullName>
            <ecNumber evidence="2 5">5.4.99.62</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rbsD</name>
        <name evidence="6" type="ORF">ADN00_05650</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the interconversion of beta-pyran and beta-furan forms of D-ribose.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>beta-D-ribopyranose = beta-D-ribofuranose</text>
            <dbReference type="Rhea" id="RHEA:25432"/>
            <dbReference type="ChEBI" id="CHEBI:27476"/>
            <dbReference type="ChEBI" id="CHEBI:47002"/>
            <dbReference type="EC" id="5.4.99.62"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Carbohydrate metabolism; D-ribose degradation; D-ribose 5-phosphate from beta-D-ribopyranose: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodecamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the RbsD / FucU family. RbsD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.62" evidence="2 5"/>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78726.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061996.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05650"/>
    <dbReference type="EnsemblBacteria" id="KPL78726">
        <property type="protein sequence ID" value="KPL78726"/>
        <property type="gene ID" value="ADN00_05650"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00916">
        <property type="reaction ID" value="UER00888"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0062193">
        <property type="term" value="F:D-ribose pyranase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016872">
        <property type="term" value="F:intramolecular lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048029">
        <property type="term" value="F:monosaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019303">
        <property type="term" value="P:D-ribose catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1650.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01661">
        <property type="entry name" value="D_rib_pyranase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023064">
        <property type="entry name" value="D-ribose_pyranase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023750">
        <property type="entry name" value="RbsD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007721">
        <property type="entry name" value="RbsD_FucU"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37831">
        <property type="entry name" value="PTHR37831"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05025">
        <property type="entry name" value="RbsD_FucU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102546">
        <property type="entry name" value="SSF102546"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="3 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="119"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="20"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="28"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="97"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL78726.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="132" mass="14287" checksum="40E9EA699531B850" modified="2016-01-20" version="1">MKKGMLINAPISALVSEMGHTDTLTICDSGLPTYELRRIDLALRPGVPGFLETVETVLAELQVEKAYLSEDIVQKNPTVLAGLKKLLGDTPIELIPHVDFKEKVKASKGIVRTGECTPFANVILVAGVTFKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XPW3</accession>
    <name>A0A0P6XPW3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 14">Inosine-5'-monophosphate dehydrogenase</fullName>
            <shortName evidence="7">IMP dehydrogenase</shortName>
            <shortName evidence="7">IMPD</shortName>
            <shortName evidence="7">IMPDH</shortName>
            <ecNumber evidence="7 14">1.1.1.205</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">guaB</name>
        <name evidence="16" type="ORF">ADN00_05755</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7 14">
            <text>H2O + IMP + NAD(+) = H(+) + NADH + XMP</text>
            <dbReference type="Rhea" id="RHEA:11708"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="EC" id="1.1.1.205"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="7">Mycophenolic acid (MPA) is a non-competitive inhibitor that prevents formation of the closed enzyme conformation by binding to the same site as the amobile flap. In contrast, mizoribine monophosphate (MZP) is a competitive inhibitor that induces the closed conformation. MPA is a potent inhibitor of mammalian IMPDHs but a poor inhibitor of the bacterial enzymes. MZP is a more potent inhibitor of bacterial IMPDH.</text>
    </comment>
    <comment type="pathway">
        <text evidence="7 14">Purine metabolism; XMP biosynthesis via de novo pathway; XMP from IMP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 13">Belongs to the IMPDH/GMPR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.205" evidence="7 14"/>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78744.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062015.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05755"/>
    <dbReference type="EnsemblBacteria" id="KPL78744">
        <property type="protein sequence ID" value="KPL78744"/>
        <property type="gene ID" value="ADN00_05755"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1627"/>
    <dbReference type="UniPathway" id="UPA00601">
        <property type="reaction ID" value="UER00295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003938">
        <property type="term" value="F:IMP dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006177">
        <property type="term" value="P:GMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00381">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01964">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000644">
        <property type="entry name" value="CBS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046342">
        <property type="entry name" value="CBS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005990">
        <property type="entry name" value="IMP_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015875">
        <property type="entry name" value="IMP_DH/GMP_Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001093">
        <property type="entry name" value="IMP_DH_GMPRt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11911">
        <property type="entry name" value="PTHR11911"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00571">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00478">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000130">
        <property type="entry name" value="IMPDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00116">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54631">
        <property type="entry name" value="SSF54631"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01302">
        <property type="entry name" value="IMP_dehydrog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51371">
        <property type="entry name" value="CBS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00487">
        <property type="entry name" value="IMP_DH_GMP_RED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12" id="KW-0129">CBS domain</keyword>
    <keyword evidence="3 7 14" id="KW-0332">GMP biosynthesis</keyword>
    <keyword evidence="2 7 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10 14" id="KW-0520">NAD</keyword>
    <keyword evidence="5 7 13" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 7 11" id="KW-0630">Potassium</keyword>
    <keyword evidence="7 14" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBS" evidence="15">
        <location>
            <begin position="96"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="CBS" evidence="15">
        <location>
            <begin position="159"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="IMP binding" evidence="7 9">
        <location>
            <begin position="343"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="IMP binding" evidence="7 9">
        <location>
            <begin position="366"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="IMP binding" evidence="7 9">
        <location>
            <begin position="390"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="active site" description="Thioimidate intermediate" evidence="7 8">
        <location>
            <position position="310"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7 8">
        <location>
            <position position="406"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="253"/>
            <end position="255"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="253"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 10">
        <location>
            <begin position="303"/>
            <end position="305"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 11">
        <location>
            <position position="305"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 11">
        <location>
            <position position="307"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="308"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 11">
        <location>
            <position position="310"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7 9">
        <location>
            <position position="420"/>
        </location>
        <ligand>
            <name>IMP</name>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="474"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="475"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="476"/>
        </location>
        <ligand>
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
            <note>ligand shared between two tetrameric partners</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022749"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000130-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00703"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU003928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KPL78744.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="493" mass="52103" checksum="DC852325E5A8B288" modified="2016-01-20" version="1">MNEELFEGADALTFDDVLIQPGYSEILPSETDVSALLVPTIRLNIPLLSAAMDTVTEARLAIALAREGGIGIIHRNLSPDAQAKEVETVKRSESGMISDPITLSPTASLQDAEDIMARFHISGIPIVDPESRKLVGILTNRDIRFAEPEDYYKPVSEFMTSGRLVTAPIGTTLEQAKAILQKHRIEKLPLVDEGGRLAGLITVKDIQKKLKYPNAATDARGRLMVGAAVGVGADVEERISLMVAKGLDVVVIDTAHGHSAGVVKSIQRIHAMLPDLPIIAGNVVTEEGAIALMDAGASAIKVGVGAGSICTTRVISGAGMPQLTAVYRVAKAARPRGIPVIADGGVKYSGDIVKALVAGADTVMLGSLLAGLEEAPGESVLYEGRKYKTYRGMGSMGAMQGYGRDRYGSGQGGAKKLVPEGVEGMVAFKGALSDFVYQLVGGLRSGMGYAGAKNLEELRTKTRLLRITGAGLIESHPHDVTITREAPNYQRGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XR68</accession>
    <name>A0A0P6XR68_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_16165</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064078.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16165"/>
    <dbReference type="EnsemblBacteria" id="KPL72112">
        <property type="protein sequence ID" value="KPL72112"/>
        <property type="gene ID" value="ADN00_16165"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="SSF54928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RRM" evidence="2">
        <location>
            <begin position="1"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL72112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="101" mass="10880" checksum="C1232EC03F5053A7" modified="2016-01-20" version="1">MSYSTTEEQLRSMFEEAGTVVSVDVIKDRETGRPKGFAFVAMGSQEDANKAISMFNGKDVGGRQLTVNPARPREERPAGGRSFGSGNRGGGNRGGYGNNRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XRU9</accession>
    <name>A0A0P6XRU9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L35</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_13175</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL35 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000030">
        <property type="protein sequence ID" value="KPL75183.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13175"/>
    <dbReference type="EnsemblBacteria" id="KPL75183">
        <property type="protein sequence ID" value="KPL75183"/>
        <property type="gene ID" value="ADN00_13175"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2886"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.410.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021137">
        <property type="entry name" value="Ribosomal_L35"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001706">
        <property type="entry name" value="Ribosomal_L35_non-mt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037229">
        <property type="entry name" value="Ribosomal_L35_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33343">
        <property type="entry name" value="PTHR33343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01632">
        <property type="entry name" value="Ribosomal_L35p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00064">
        <property type="entry name" value="RIBOSOMALL35"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143034">
        <property type="entry name" value="SSF143034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL75183.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="69" mass="7924" checksum="AE5DE8AF5B5756F2" modified="2016-01-20" version="1">MKLKTHKATSKRFRLTGSGKLMRTKGGKSHLRRRTSVRTKALLSEMIPVEGTGIVKRVKRLAPYMKERE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XSX3</accession>
    <name>A0A0P6XSX3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N_BRCA1_IG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_11785</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063215.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76033">
        <property type="protein sequence ID" value="KPL76033"/>
        <property type="gene ID" value="ADN00_11785"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032350">
        <property type="entry name" value="N_BRCA1_central"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16158">
        <property type="entry name" value="N_BRCA1_IG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N_BRCA1_IG" evidence="1">
        <location>
            <begin position="120"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="211" mass="23057" checksum="5775C3C858DF5B14" modified="2016-01-20" version="1">MLRSRLIFSLFLLVLLSLSLTSCGILSTPMPTPDITAVVESARHTMVAEITLTALLNPSSTPTPQPTYTPYPTYTPIPPTETPVGDTPTPEPTATQKIIGDYAQPVYTSTYPENRREYFANELFNIAWGLKNIGTTTWNTGYALIYTGGDKFTNVDRIPLDRIVAPGEKGEFNLGAFGSEDIRTHTTYWALVNDKGQLVPGGAVSFSYTGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XSY8</accession>
    <name>A0A0P6XSY8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glyco_trans_2-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_12035</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063262.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76070">
        <property type="protein sequence ID" value="KPL76070"/>
        <property type="gene ID" value="ADN00_12035"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="40"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="316" mass="36247" checksum="E9A67F5510A58547" modified="2016-01-20" version="1">MRIGQNPAKFVKSVAKPERVTVAVLNYIPFLSGFYADMLDVLKTSLNGIRESADLPFDLMVFDNGSCAEVKDYLLAEQSAGRVQYLLLSEKNLGKGGAWNMIFSGAPGEIICYADNDCLFSKGFLSKSLELLEGFPNVGMVTARPYRTRPEYYTSTVAWGESQPEVTVERGDFIPWEVFLEFDLSLGQSEEEIRARYAETEDVRFRYRDLQALAGASHWQFTARKDTLQQFLPFDMDRPMGQVKQLDQRMNEAGLLRLMPVEPYAMNLSNTLRGLQGQTQQQPQSAQKYRLLDLPMVKKPLLWLYDSIFRWYYDRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XTJ7</accession>
    <name>A0A0P6XTJ7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_06860</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000018">
        <property type="protein sequence ID" value="KPL78437.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062239.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000018.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06860"/>
    <dbReference type="EnsemblBacteria" id="KPL78437">
        <property type="protein sequence ID" value="KPL78437"/>
        <property type="gene ID" value="ADN00_06860"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2288"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002878">
        <property type="entry name" value="DUF35_OB-fold_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022002">
        <property type="entry name" value="DUF35_Znr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12172">
        <property type="entry name" value="DUF35_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01796">
        <property type="entry name" value="OB_aCoA_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF35_N" evidence="2">
        <location>
            <begin position="10"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="domain" description="OB_aCoA_assoc" evidence="1">
        <location>
            <begin position="47"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01796"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78437.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="132" mass="14838" checksum="11E91DBEA4DD7ADA" modified="2016-01-20" version="1">MENPRHWRLKKQRYALVGEECPHCHVKLFPPRDVCPHCGGEAKEEFAFSGKGEVFSYTVMHDAPTGYQEATPFTVALVKLAEGPVVTAQLTDLGDQPVRIGMPVEMVTRKIRTDDGDRGMILYGYKFRPVMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XTX9</accession>
    <name>A0A0P6XTX9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PA14 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_06590</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000017">
        <property type="protein sequence ID" value="KPL78583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062185.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000017.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06590"/>
    <dbReference type="EnsemblBacteria" id="KPL78583">
        <property type="protein sequence ID" value="KPL78583"/>
        <property type="gene ID" value="ADN00_06590"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037524">
        <property type="entry name" value="PA14/GLEYA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011658">
        <property type="entry name" value="PA14_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012495">
        <property type="entry name" value="TadE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07691">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07811">
        <property type="entry name" value="TadE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00758">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51820">
        <property type="entry name" value="PA14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="domain" description="PA14" evidence="3">
        <location>
            <begin position="329"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="811"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="811"/>
            <end position="875"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51820"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL78583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="883" mass="97820" checksum="1BFD6574CAA9C1F2" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XU39</accession>
    <name>A0A0P6XU39_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09685</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062800.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09685"/>
    <dbReference type="EnsemblBacteria" id="KPL76865">
        <property type="protein sequence ID" value="KPL76865"/>
        <property type="gene ID" value="ADN00_09685"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2394"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043747">
        <property type="entry name" value="DUF5692"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18948">
        <property type="entry name" value="DUF5692"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="225"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="254"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="304" mass="34291" checksum="494AC62B181EA9BC" modified="2016-01-20" version="1">MFLFEPVPWYSILMWFVVLGGLILMNELARINKWFALAIFLVLPAILPFTVWKHTAAPGSSVGTWFHWAKVYSALAGCLGFLAIRNLKGWGTNKYALMFPPLILAINILEAVVRDFQTVSVNGMVDGVFTIGGPWNVMNGIAGLLNIITITGWMGIFIGKDQKKDMLWPDMLWFWIIAYDLWNFAYVYNCVSDHAFYAGAALLISCTIPAFFIKKGAWLQHRAQTLAVWMMFVMTFPTFVDTSMFAVKSSHNETALFVVSALALAANVAVLVYEVYKIVKTKRNPLKEEIYTDLPAYQQVASLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XU89</accession>
    <name>A0A0P6XU89_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_10060</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062871.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76929">
        <property type="protein sequence ID" value="KPL76929"/>
        <property type="gene ID" value="ADN00_10060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="96" mass="10592" checksum="8E60CCA9707031A5" modified="2016-01-20" version="1">MEDNSYSLAGLKVTAMVYATVRSVVEHVRQTGHLPEKITAGGLHIAMRVLMEQRGRDPVLNEKEQMVLEAILRDRRLPGGGVVFVDPEPGPEKDGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUG0</accession>
    <name>A0A0P6XUG0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HTH deoR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_06005</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78784.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062063.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78784">
        <property type="protein sequence ID" value="KPL78784"/>
        <property type="gene ID" value="ADN00_06005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014036">
        <property type="entry name" value="DeoR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001034">
        <property type="entry name" value="DeoR_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018356">
        <property type="entry name" value="Tscrpt_reg_HTH_DeoR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00455">
        <property type="entry name" value="DeoRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08220">
        <property type="entry name" value="HTH_DeoR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00037">
        <property type="entry name" value="HTHLACR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00420">
        <property type="entry name" value="HTH_DEOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00894">
        <property type="entry name" value="HTH_DEOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51000">
        <property type="entry name" value="HTH_DEOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH deoR-type" evidence="4">
        <location>
            <begin position="5"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL78784.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="267" mass="30183" checksum="D1AD65CCA090A5CC" modified="2016-01-20" version="1">MSFERKKRISAITHLLQQKNEISVKEISEMMHVSEMTIRRDLDTLEEQGVVNRTHGGAVLLDPNTSVRYPYILGEQITKNTREKNLIGIKAASLVRPHETIFLDSGTTTPFVAKNLNPDLPITALCYTFTNAMELYPRANTNLILLGGLFHRDSNIFHSVENYGLIRNTRADKAFISTGGFDPEMGLTTFFDYEAAIKREMIRSARHIILVADSTKFGKISVTHFAELDDVDTIITDDGISKEYREILVDRGIELIIANQDNNQYTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUU9</accession>
    <name>A0A0P6XUU9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6 7">Protein RecA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 7">Recombinase A</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">recA</name>
        <name evidence="11" type="ORF">ADN00_03480</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Can catalyze the hydrolysis of ATP in the presence of single-stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 8">Belongs to the RecA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78967.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061575.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03480"/>
    <dbReference type="EnsemblBacteria" id="KPL78967">
        <property type="protein sequence ID" value="KPL78967"/>
        <property type="gene ID" value="ADN00_03480"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.47"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00983">
        <property type="entry name" value="recA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00268">
        <property type="entry name" value="RecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013765">
        <property type="entry name" value="DNA_recomb/repair_RecA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020584">
        <property type="entry name" value="DNA_recomb/repair_RecA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023400">
        <property type="entry name" value="RecA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020587">
        <property type="entry name" value="RecA_monomer-monomer_interface"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45900">
        <property type="entry name" value="PTHR45900"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00154">
        <property type="entry name" value="RecA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00142">
        <property type="entry name" value="RECA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54752">
        <property type="entry name" value="SSF54752"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02012">
        <property type="entry name" value="tigrfam_recA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00321">
        <property type="entry name" value="RECA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50163">
        <property type="entry name" value="RECA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8" id="KW-0227">DNA damage</keyword>
    <keyword evidence="6 8" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="6 7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="5 6 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 6 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0742">SOS response</keyword>
    <feature type="domain" description="RECA_2" evidence="9">
        <location>
            <begin position="51"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="domain" description="RECA_3" evidence="10">
        <location>
            <begin position="215"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="81"/>
            <end position="88"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL78967.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="366" mass="39587" checksum="9EEB84458E7D1603" modified="2016-01-20" version="1">MARKSTPKKTNEESPVVDQARQAVLDKALGDIIKRYGEGAIMRMGEAHHLNVEAIPTGSLSVDIALGVGGIPRGRICEIYGPESSGKTTLCLHIVAESQKSGGTAAYIDMEHALDPAYAARLGVNVDSLLVSQPDTGEQALEIAETLVRSGAIDVVVVDSVAALVPRSEIEGDMGDATMGMQARLMSQALRKLSGVIKQTNTAVIFTNQLRQKIGVMFGNPETTTGGMALKFYASVRMDIRRIQSIKMGAEVIGNRVRVRVVKNKVAPPFRTAEFDIMYNEGISKAGDILDLGTQLEIIAKRGAFYSFGDIRLGQGRENAKEFLRQNTDLADEIELSIRQQTVNGNLLPTFTEEGDDEYSGGEEEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XVB8</accession>
    <name>A0A0P6XVB8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_04905</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79187.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79187">
        <property type="protein sequence ID" value="KPL79187"/>
        <property type="gene ID" value="ADN00_04905"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79187.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="77" mass="8374" checksum="55FC74C4FF0DFD9D" modified="2016-01-20" version="1">MGHVFLCGLRFILTRSGTAIGKCWASPAHPHGFYPPAGQKHAPTFSKVILFSVGFGFVKILGLPRLACFHHINVINS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XVP3</accession>
    <name>A0A0P6XVP3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_02785</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000013">
        <property type="protein sequence ID" value="KPL79379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061437.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000013.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79379">
        <property type="protein sequence ID" value="KPL79379"/>
        <property type="gene ID" value="ADN00_02785"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="120" mass="13870" checksum="16A783DBFB03F971" modified="2016-01-20" version="1">MKSHWFTHQGKRVWFADYSHFGVESKDLQKEMDEIFEVLSREKPGSVLTLIDVTGTRGTPENFNLMRAMAVRLNPYVRKRAVIGLTGVQKTFFDLINKASGDKNYIRFEDAEAAKNWLVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XW24</accession>
    <name>A0A0P6XW24_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphate transport system permease protein PstA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_02510</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000011">
        <property type="protein sequence ID" value="KPL79580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02510"/>
    <dbReference type="EnsemblBacteria" id="KPL79580">
        <property type="protein sequence ID" value="KPL79580"/>
        <property type="gene ID" value="ADN00_02510"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2812"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035435">
        <property type="term" value="P:phosphate ion transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005672">
        <property type="entry name" value="Phosphate_PstA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00974">
        <property type="entry name" value="3a0107s02c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="176"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="222"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="263"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="380"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="7">
        <location>
            <begin position="177"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL79580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="410" mass="45070" checksum="A899F445C11F19E0" modified="2016-01-20" version="1">MSGPSLFEDNTKPRHRTARFWMSIFQISTVIAIVALSALLITIVNNAFGYVIYESKVDPDTLAVNGVEVDDLSKEELIVALQSNISQGLYRRFANDMPFEQRTREDVLALIYERVIDPKVVMQYSLIDSIFKRSEIAQYAAAEYPKAELVFQSWINWDFVKAPQSGDPLRAGVRTAVFGSLWTILFAVSLAFPIGVGAAIYLQEYAEDNWVNRVIQTNINNLAGVPSIIYGILGLAIFVRLLEKLTSGAVFGVVDPTTANGRTVLSAGLTLGLLILPTIIINAQEAIKAVPNSLKQASYGLGATRWQTVWHHVLPNALPGIMTGTILAISRAIGETAPLVVVGASTFITMDPNGPFSKFTTLPIQIYQWTSRPQDLFRNIAAAAILVLLIMLLSLNASAILLRNRFSNRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XWJ1</accession>
    <name>A0A0P6XWJ1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AcnX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_07980</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77816.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062461.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07980"/>
    <dbReference type="EnsemblBacteria" id="KPL77816">
        <property type="protein sequence ID" value="KPL77816"/>
        <property type="gene ID" value="ADN00_07980"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.596"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01355">
        <property type="entry name" value="AcnX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007506">
        <property type="entry name" value="AcnX_catalytic_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04412">
        <property type="entry name" value="AcnX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AcnX" evidence="1">
        <location>
            <begin position="1"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77816.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="398" mass="42721" checksum="AB6CE2BDA881DBAA" modified="2016-01-20" version="1">MNLTPLQTAMLDGAHGRAAQKSMQILAALGKIYGAEELIPVTSVQIAGVSYANLGEAGLAFLSDMADGGGKTRVLTTLNPAGMDIENWQALGISPEFARDQTRVIEAFSRMGVVATCSCTPYLVGNVPLYGQHIAWSESSAVCFANSVLGARTNREGGPSALASALTGFSPAYGLHLDEQRVPRLHFHVEAPLSGTFQFGALGKVIGEIIEKRATRPVPYLTGIPQASLEELKSFCASIATYGGAGLFHIQGVTPEASLFAVPAESITISSQQIHQAIEHLSNAADEPDFISLGCPHLSIDEIAHLAQLLVGRQVRKEFWITTARPIKQMADRMGYTRIIEQAGAKFAADTCCVVAPIQGRFKTLLTDSAKACYYARGKNKFNTLYRSFEEVVNEATR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XWY3</accession>
    <name>A0A0P6XWY3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glyco_trans_2-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_00485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060992.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL81048">
        <property type="protein sequence ID" value="KPL81048"/>
        <property type="gene ID" value="ADN00_00485"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="16"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL81048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="312" mass="35651" checksum="029138CCA6EC3D2C" modified="2016-01-20" version="1">MARKNEFNKSYPSVWIIIINWNRWTDTEACLKSLEDLTYPNFSVLVVDNGSTDGSVERLKRLNGINTILLKTNEGFVGGNNIGVDYARKYQPDYFLLLNNDTLVDAHFLSRLVTALESTPDIGIAGPLICYAGLPDTIWSAGGSIDLSRGETSMVGIGQKKELFDTRSPFSVDFVTGCALLVKRQVIDEIGFLDDRFFAYYEETEFCVRARKNGWGCVVVPQALIWHKITPEARAASENVHYYMTRNRLLFIRLSKMGWLVYLRALAEDLRTLVSWSIRLKWKNQRRLRKAHIQALMDNLGNRWGKRIVRAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XWY8</accession>
    <name>A0A0P6XWY8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_08405</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77917">
        <property type="protein sequence ID" value="KPL77917"/>
        <property type="gene ID" value="ADN00_08405"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06259">
        <property type="entry name" value="YdcF-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003848">
        <property type="entry name" value="DUF218"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02698">
        <property type="entry name" value="DUF218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF218" evidence="1">
        <location>
            <begin position="51"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="217" mass="24156" checksum="A3C5B85F73D3DD44" modified="2016-01-20" version="1">MVKKMLWNIVKIGVLLVISVAALFGVTRLIVIAATSASIKSQTSNLSPAPVAIVFGAGLTRDGLPTPVLRDRVKAAADLYFEGKVQKLLMSGDNRFENYNEPQAMWEYAIQLGVPPEDIVQDFAGRRTYDTCYRARHIFGVKNAILVTQQFHLPRALYLCKNMGIQSTGYASDLRNYSRTSRAIWSIREIPATATAIFDVWIRKPIPVLGPQEKISD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XX60</accession>
    <name>A0A0P6XX60_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Alanine--tRNA ligase</fullName>
            <ecNumber evidence="9">6.1.1.7</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Alanyl-tRNA synthetase</fullName>
            <shortName evidence="9">AlaRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="primary">alaS</name>
        <name evidence="11" type="ORF">ADN00_00895</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Catalyzes the attachment of alanine to tRNA(Ala) in a two-step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>ATP + L-alanine + tRNA(Ala) = AMP + diphosphate + L-alanyl-tRNA(Ala)</text>
            <dbReference type="Rhea" id="RHEA:12540"/>
            <dbReference type="Rhea" id="RHEA-COMP:9657"/>
            <dbReference type="Rhea" id="RHEA-COMP:9923"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78497"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="9">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="9">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="9">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="9">Consists of three domains; the N-terminal catalytic domain, the editing domain and the C-terminal C-Ala domain. The editing domain removes incorrectly charged amino acids, while the C-Ala domain, along with tRNA(Ala), serves as a bridge to cooperatively bring together the editing and aminoacylation centers thus stimulating deacylation of misacylated tRNAs.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 9">Belongs to the class-II aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.7" evidence="9"/>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061064.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00895"/>
    <dbReference type="EnsemblBacteria" id="KPL81112">
        <property type="protein sequence ID" value="KPL81112"/>
        <property type="gene ID" value="ADN00_00895"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3577"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004813">
        <property type="term" value="F:alanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006419">
        <property type="term" value="P:alanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00036_B">
        <property type="entry name" value="Ala_tRNA_synth_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002318">
        <property type="entry name" value="Ala-tRNA-lgiase_IIc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018162">
        <property type="entry name" value="Ala-tRNA-ligase_IIc_anticod-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018165">
        <property type="entry name" value="Ala-tRNA-synth_IIc_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018164">
        <property type="entry name" value="Ala-tRNA-synth_IIc_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023033">
        <property type="entry name" value="Ala_tRNA_ligase_euk/bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003156">
        <property type="entry name" value="DHHA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018163">
        <property type="entry name" value="Thr/Ala-tRNA-synth_IIc_edit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012947">
        <property type="entry name" value="tRNA_SAD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02272">
        <property type="entry name" value="DHHA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01411">
        <property type="entry name" value="tRNA-synt_2c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07973">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00980">
        <property type="entry name" value="TRNASYNTHALA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00863">
        <property type="entry name" value="tRNA_SAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101353">
        <property type="entry name" value="SSF101353"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55186">
        <property type="entry name" value="SSF55186"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00344">
        <property type="entry name" value="alaS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50860">
        <property type="entry name" value="AA_TRNA_LIGASE_II_ALA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8 9" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="5 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 9" id="KW-0436">Ligase</keyword>
    <keyword evidence="9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7 9" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 9" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 9" id="KW-0820">tRNA-binding</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="AA_TRNA_LIGASE_II_ALA" evidence="10">
        <location>
            <begin position="5"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="595"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="599"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="700"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="704"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00036"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL81112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="911" mass="100409" checksum="E890B82AB807447B" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XXX6</accession>
    <name>A0A0P6XXX6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Threonine aldolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_07110</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the threonine aldolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78237.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062289.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07110"/>
    <dbReference type="EnsemblBacteria" id="KPL78237">
        <property type="protein sequence ID" value="KPL78237"/>
        <property type="gene ID" value="ADN00_07110"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3240"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:cellular amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001597">
        <property type="entry name" value="ArAA_b-elim_lyase/Thr_aldolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023603">
        <property type="entry name" value="Low_specificity_L-TA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48097:SF9">
        <property type="entry name" value="PTHR48097:SF9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01212">
        <property type="entry name" value="Beta_elim_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017617">
        <property type="entry name" value="Thr_aldolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Beta_elim_lyase" evidence="5">
        <location>
            <begin position="5"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="4">
        <location>
            <position position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR017617-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL78237.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="347" mass="36819" checksum="FA154E4E96307C23" modified="2016-01-20" version="1">MQWIDLRSDTVTQPTAEMRAVMVEAVVGDDVYGEDPTVQRLQAMSAERLGKEAGLFVPSGTMGNLIGVLAHCGRGDEVIMGSLAHTFLFEAGGVAALGGVHPHTLPNLPDGTIALEDIRLAVRDANNPHYPTSRLIVLENTHNRCGGVAVPVEFMLAVKEIADANGLKMHLDGARIFNAETELGVAAAELAQPFDSVTFCLSKGLCAPVGSVLCGSKPFIQQALRLRKMLGGGMRQAGILAAAGIIALEKMTLRLGEDHRRAAELGDLLASVDGLRVEKKAHATNMVFVNLDESIQGSAGEIAGRLKSLGVLASPTGARQFRLVLHYWISDADVKATAQAFRQALSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XY95</accession>
    <name>A0A0P6XY95_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GTP cyclohydrolase 1</fullName>
            <ecNumber evidence="5">3.5.4.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">GTP cyclohydrolase I</fullName>
            <shortName evidence="5">GTP-CH-I</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">folE</name>
        <name evidence="7" type="ORF">ADN00_00630</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>GTP + H2O = 7,8-dihydroneopterin 3'-triphosphate + formate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17473"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:58462"/>
            <dbReference type="EC" id="3.5.4.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Cofactor biosynthesis; 7,8-dihydroneopterin triphosphate biosynthesis; 7,8-dihydroneopterin triphosphate from GTP: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homopolymer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the GTP cyclohydrolase I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.16" evidence="5"/>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00630"/>
    <dbReference type="EnsemblBacteria" id="KPL81143">
        <property type="protein sequence ID" value="KPL81143"/>
        <property type="gene ID" value="ADN00_00630"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3521"/>
    <dbReference type="UniPathway" id="UPA00848">
        <property type="reaction ID" value="UER00151"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003934">
        <property type="term" value="F:GTP cyclohydrolase I activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035998">
        <property type="term" value="P:7,8-dihydroneopterin 3'-triphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006730">
        <property type="term" value="P:one-carbon metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.286.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00223">
        <property type="entry name" value="FolE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043133">
        <property type="entry name" value="GTP-CH-I_C/QueF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043134">
        <property type="entry name" value="GTP-CH-I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001474">
        <property type="entry name" value="GTP_CycHdrlase_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018234">
        <property type="entry name" value="GTP_CycHdrlase_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020602">
        <property type="entry name" value="GTP_CycHdrlase_I_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11109">
        <property type="entry name" value="PTHR11109"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01227">
        <property type="entry name" value="GTP_cyclohydroI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00063">
        <property type="entry name" value="folE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00859">
        <property type="entry name" value="GTP_CYCLOHYDROL_1_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00860">
        <property type="entry name" value="GTP_CYCLOHYDROL_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="4 5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3 5" id="KW-0554">One-carbon metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="GTP_cyclohydroI" evidence="6">
        <location>
            <begin position="2"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00223"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL81143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="183" mass="21016" checksum="A57E26B41722D2D0" modified="2016-01-20" version="1">MSVHDLLTNIGEDPEREGLLNTPDRIARMYDELTAGYHVDTEKLINGALFNVDYDEMVIVKDIEFYSLCEHHMLPFFGRAHVAYIPDGKVIGLSKIPRIVEMFARRLQVQERMTKQIADFIKETIQPKGVAVVVEGVHMCSMMRGVKKAEASMITSAYLDQLKNNRDLRTEFIDHINSRRSMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XYA0</accession>
    <name>A0A0P6XYA0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">Homoserine dehydrogenase</fullName>
            <ecNumber evidence="5 11">1.1.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">ADN00_14070</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>L-homoserine + NAD(+) = H(+) + L-aspartate 4-semialdehyde + NADH</text>
            <dbReference type="Rhea" id="RHEA:15757"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57476"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="1.1.1.3"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>L-homoserine + NADP(+) = H(+) + L-aspartate 4-semialdehyde + NADPH</text>
            <dbReference type="Rhea" id="RHEA:15761"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57476"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:537519"/>
            <dbReference type="EC" id="1.1.1.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 11">Amino-acid biosynthesis; L-methionine biosynthesis via de novo pathway; L-homoserine from L-aspartate: step 3/3.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 3/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="12">Belongs to the homoserine dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.3" evidence="5 11"/>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063663.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000033.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14070"/>
    <dbReference type="EnsemblBacteria" id="KPL74124">
        <property type="protein sequence ID" value="KPL74124"/>
        <property type="gene ID" value="ADN00_14070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1914"/>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00063"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00051">
        <property type="reaction ID" value="UER00465"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004412">
        <property type="term" value="F:homoserine dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005106">
        <property type="entry name" value="Asp/hSer_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001342">
        <property type="entry name" value="HDH_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019811">
        <property type="entry name" value="HDH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022697">
        <property type="entry name" value="HDH_short"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00742">
        <property type="entry name" value="Homoserine_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03447">
        <property type="entry name" value="NAD_binding_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036497">
        <property type="entry name" value="HDH_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01042">
        <property type="entry name" value="HOMOSER_DHGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0412">Isoleucine biosynthesis</keyword>
    <keyword evidence="11" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="7 10 11" id="KW-0521">NADP</keyword>
    <keyword evidence="8 11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0791">Threonine biosynthesis</keyword>
    <feature type="domain" description="NAD_binding_3" evidence="14">
        <location>
            <begin position="10"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="Homoserine_dh" evidence="13">
        <location>
            <begin position="161"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="9">
        <location>
            <position position="227"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="10"/>
            <end position="15"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="128"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="212"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR036497-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR036497-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000579"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU004171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF03447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KPL74124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="345" mass="36318" checksum="92F0185FA6EF1E1C" modified="2016-01-20" version="1">MRTYSIVLIGFGNVGQGLAQILAERSQELAERFGVEYKITAVCDLLKGSVFDPAGLSPAALLQAAAQGQPLSSLPAAHTGWDAQRTLQECGADILCEMSYTDLKTGQPAINHVETALKAGMHVVTTNKGPIALDYPRLAALAQERGLELGVEGTVMSGTPALRLGSELLAGAGIRKIQGIFNGTTNYILTRMAAGDSYTAALAEAQRLGFAEADPTGDVEGFDAAGKVVILANLLMGAHITMQDVDRQGITALTPTDIEQAESQGQRWKLIGSLEKKDDRLTASVQPTRVAHSHPLAGVSGATNAITYTTDLLGDVTLIGPGAGRLETGYALLEDMLAIHRRQSN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XZ18</accession>
    <name>A0A0P6XZ18_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphopantetheine adenylyltransferase</fullName>
            <ecNumber evidence="6">2.7.7.3</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Dephospho-CoA pyrophosphorylase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Pantetheine-phosphate adenylyltransferase</fullName>
            <shortName evidence="6">PPAT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6 8" type="primary">coaD</name>
        <name evidence="8" type="ORF">ADN00_13785</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Reversibly transfers an adenylyl group from ATP to 4'-phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>(R)-4'-phosphopantetheine + ATP + H(+) = 3'-dephospho-CoA + diphosphate</text>
            <dbReference type="Rhea" id="RHEA:19801"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57328"/>
            <dbReference type="ChEBI" id="CHEBI:61723"/>
            <dbReference type="EC" id="2.7.7.3"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="6">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 4/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homohexamer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the bacterial CoaD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.3" evidence="6"/>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063605.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000032.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13785"/>
    <dbReference type="EnsemblBacteria" id="KPL74361">
        <property type="protein sequence ID" value="KPL74361"/>
        <property type="gene ID" value="ADN00_13785"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1334"/>
    <dbReference type="UniPathway" id="UPA00241">
        <property type="reaction ID" value="UER00355"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004595">
        <property type="term" value="F:pantetheine-phosphate adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02163">
        <property type="entry name" value="PPAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00151">
        <property type="entry name" value="PPAT_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001980">
        <property type="entry name" value="PPAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21342:SF1">
        <property type="entry name" value="PTHR21342:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01467">
        <property type="entry name" value="CTP_transf_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01020">
        <property type="entry name" value="LPSBIOSNTHSS"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01510">
        <property type="entry name" value="coaD_prev_kdtB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 6" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 6 8" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CTP_transf_like" evidence="7">
        <location>
            <begin position="6"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="9"/>
            <end position="10"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="17"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="87"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="88"/>
            <end position="90"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="123"/>
            <end position="129"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="6">
        <location>
            <position position="17"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00029346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01467"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL74361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="174" mass="19797" checksum="823B9D25590533B4" modified="2016-01-20" version="1">MVKAVFPATFDPIHYGHIDIAYRASKMFDEVVVAVYDKPLKNLVFTPEERLQMARLAFESNSKINVVGYSGLTVDFCRKINAQVIVRGLRVFSDFEYEFRMALANHRLAPEIEVVALITSEQHSFLSSSTVREIAALGGDVSSMVPPHVERALKFRYQELSQEKEYIPHSSLRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y3E0</accession>
    <name>A0A0P6Y3E0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SpoVT-AbrB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_02660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000012">
        <property type="protein sequence ID" value="KPL79435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061414.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000012.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02660"/>
    <dbReference type="EnsemblBacteria" id="KPL79435">
        <property type="protein sequence ID" value="KPL79435"/>
        <property type="gene ID" value="ADN00_02660"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007159">
        <property type="entry name" value="SpoVT-AbrB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037914">
        <property type="entry name" value="SpoVT-AbrB_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04014">
        <property type="entry name" value="MazE_antitoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00966">
        <property type="entry name" value="SpoVT_AbrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89447">
        <property type="entry name" value="SSF89447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01439">
        <property type="entry name" value="lp_hng_hel_AbrB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SpoVT-AbrB" evidence="1">
        <location>
            <begin position="6"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="69" mass="7739" checksum="4BBD25152D7A0C29" modified="2016-01-20" version="1">MKKRPIIITATNAITIPKKVRNLLDLQPGDCLDYEVMANGSIILVRKECCDSPSLRPTCKLPCQAQKRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y4P6</accession>
    <name>A0A0P6Y4P6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Putrescine carbamoyltransferase</fullName>
            <ecNumber evidence="6">2.1.3.3</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_11455</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the aspartate/ornithine carbamoyltransferase superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.3.3" evidence="6"/>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76565.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063150.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11455"/>
    <dbReference type="EnsemblBacteria" id="KPL76565">
        <property type="protein sequence ID" value="KPL76565"/>
        <property type="gene ID" value="ADN00_11455"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.992"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016597">
        <property type="term" value="F:amino acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004585">
        <property type="term" value="F:ornithine carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050231">
        <property type="term" value="F:putrescine carbamoyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033390">
        <property type="term" value="P:putrescine biosynthetic process from arginine via N-carbamoylputrescine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1370">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006132">
        <property type="entry name" value="Asp/Orn_carbamoyltranf_P-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006130">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036901">
        <property type="entry name" value="Asp/Orn_carbamoylTrfase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006131">
        <property type="entry name" value="Asp_carbamoyltransf_Asp/Orn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002292">
        <property type="entry name" value="Orn/put_carbamltrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024903">
        <property type="entry name" value="PtcA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00185">
        <property type="entry name" value="OTCace"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02729">
        <property type="entry name" value="OTCace_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00100">
        <property type="entry name" value="AOTCASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00102">
        <property type="entry name" value="OTCASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53671">
        <property type="entry name" value="SSF53671"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00658">
        <property type="entry name" value="orni_carb_tr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04384">
        <property type="entry name" value="putr_carbamoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00097">
        <property type="entry name" value="CARBAMOYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0620">Polyamine biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="OTCace_N" evidence="5">
        <location>
            <begin position="4"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="OTCace" evidence="4">
        <location>
            <begin position="154"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL76565.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="338" mass="38223" checksum="7F9017C9122DFDA5" modified="2016-01-20" version="1">MTLKHFIHTYDFSKEELLDMIETTRLIKEADRQGCTPHLLEGATLAMIFEEPSTRTRISFEVAMTELGGHALYLKPGEIHLGARESLGDTAKVISRMTDVVMIRALKHETVTGFAKDATVPVLNGLTDYNHPTQVICDVFTMMEHMPAGKKLEDLNVTFIGDATNVCSSLMFITTRLGMHFTHGAPKKYQAPEAWQKIAEENCKLSGGSFRITDNPVEAVKDADFIYTDLWWWVGQEDEIPERRAAFMPDYQVNMDLLKKAPATAKVMHCLPASRGVEATDEVLDSPQSIIFDQAENRLHAEKGLLVYFVYPRLKRPSEALKAFHQGRIEDFLEKKLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y4Q7</accession>
    <name>A0A0P6Y4Q7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_11510</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063159.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11510"/>
    <dbReference type="EnsemblBacteria" id="KPL76574">
        <property type="protein sequence ID" value="KPL76574"/>
        <property type="gene ID" value="ADN00_11510"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015577">
        <property type="term" value="F:galactitol transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013853">
        <property type="entry name" value="GatC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004703">
        <property type="entry name" value="PTS_sugar-sp_permease"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37324">
        <property type="entry name" value="PTHR37324"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03611">
        <property type="entry name" value="EIIC-GAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="14"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="46"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="100"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="137"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="231"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="255"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="297"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="325"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="363"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="425"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL76574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="461" mass="49327" checksum="171EA7CE54ED77DE" modified="2016-01-20" version="1">MDFNQIFSTILDPVLNAGPLFMIFIVFTVIGLLVRLGPVRAIRNGLMISVGFSGVYIIVDYFLAKVAPAATALAERFGGVFTYTDIGWAAFASFAFSSPLAYAVIAISLGVNLLMIFTNMTDTLNLNIWDTWEATIATLIIFGLTGNALVALVFSGMLAWLNLMISDWYALKGYCADYGFEGISFYQGTNVSWGIFAHYVARLLDKIPATSKATFTPEYVQEKFGVIGEPAVLGGIIGALMGIGAGFFWTDVVMLMISLATALVLLPMMSGIVMQALVPVSEAAAKFMKEKTGGRELFIGVDPAIAVGNTTVLATTVLMVPVLLLLAFIIPGAVNVPLADLPALLFFWVFVAAPNRFDMLRTFVTTILMGIIGTFVSIAVAPWLTMVAINQGLEVAEGTGVTSWFGHLTPEFLFAGLYGSNFNTLGLPGLIVIIAVVVLATGALRMRHNKAMKAKAAAVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y5L6</accession>
    <name>A0A0P6Y5L6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">DEAD/DEAH box helicase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_09795</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062820.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09795"/>
    <dbReference type="EnsemblBacteria" id="KPL76885">
        <property type="protein sequence ID" value="KPL76885"/>
        <property type="gene ID" value="ADN00_09795"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2416"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 3 7" id="KW-0347">Helicase</keyword>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="5">
        <location>
            <begin position="50"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="6">
        <location>
            <begin position="244"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="457"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="457"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL76885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="499" mass="56085" checksum="3B1373420471D9FB" modified="2016-01-20" version="1">MDEITPNNPTSADIPEVLPEATLADLPEKLRQGVALAGWNELLPVQAKAIPYLFSQRDMMIQSRTGSGKTGAYLLPLLEMVNPLQNETQALILVPTRELALQVATEAELLGQTTGVRSVAVYGGVGYRTQLDAFKAGAHIIIGTPGRILDHLLRRSLSLQHLRFLIFDEADRMLSMGFYPDMRRVKTYLPEQPISTYMFSATFPPQVMRLTSQFMRDPGFINLSSDHIHVTETEHVFYTVPGMDKDRRLVRIIEVENPLSAIIFCNTKVRVEYVATVLQRFGYDADILTSDLSQAAREKVLTRVRQGTLRFLVATDVAARGIDLPELSHVIQYEPPEDPEAYIHRAGRTGRAGASGTAITLVDALERVSLRRIGQRYEFTIEERPLPTDEVVQQVVAERVITLLEARLRARDNLQTVRMQRFLPLARALNESDEELGLLAMLLDDFYQETFHAPVVPSAEEEKQDVRSHSRRPVPHSAEGTGQKSGRSSRRSRGRRRPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y6K7</accession>
    <name>A0A0P6Y6K7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PseudoU_synth_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_00580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81062.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061008.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00580"/>
    <dbReference type="EnsemblBacteria" id="KPL81062">
        <property type="protein sequence ID" value="KPL81062"/>
        <property type="gene ID" value="ADN00_00580"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140098">
        <property type="term" value="F:catalytic activity, acting on RNA"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034470">
        <property type="term" value="P:ncRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001522">
        <property type="term" value="P:pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02869">
        <property type="entry name" value="PseudoU_synth_RluA_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PseudoU_synth_2" evidence="1">
        <location>
            <begin position="13"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL81062.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="228" mass="25798" checksum="DC75FEA1830387DD" modified="2016-01-20" version="1">MTNLPLLYIDEAIIVADKPSGLLSIPDGYQPDLENCLAILQQSYGKLYVTHRLDKDTSGILVFARSAEAHQIINSQFQNRHVKKVYLAWVSGEFEQQQVEVSTPLRVNADRKHRTLPDPQRGKPAGTQVRLLESRDFGSFVAAYPSTGYTHQIRSHLAFINHPVLFDPLYNPLYKPQKNGQTHSPEQRLMLHSYQLQFAHPASFHNIIFTAPIPADFLPPLCSTESLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y955</accession>
    <name>A0A0P6Y955_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">POTRA_1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_07410</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78284.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062346.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78284">
        <property type="protein sequence ID" value="KPL78284"/>
        <property type="gene ID" value="ADN00_07410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013685">
        <property type="entry name" value="POTRA_FtsQ_type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08478">
        <property type="entry name" value="POTRA_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="87"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="POTRA_1" evidence="3">
        <location>
            <begin position="117"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL78284.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="337" mass="37184" checksum="6DA38C9C85ADDB6D" modified="2016-01-20" version="1">MAERSSATTRADQVRARRSTQSSQRATQAKQRIRYASEAPQVIVRGNIGTPVARRASTHPRRKIAIPLGQPGAELHMPAIPMVNPGWKLLSALITIAMLALISLMYNLPVFQVGIPEVEGVSRISPLDVAAALNLQGLPVFTIDPQTVQQQVERAFIDLKDVKVSVAFPNQVRITAVERQPIIRWHAEGLEYWSDNEGVLLPVRGDMENLLLIEVNGALPVVKAEPVAKEEQTPEMAAIQALNPVQARQVQPEATEAAIKLRTFLPAEITSLAYSEADGIGWTDPRGWQVFIGNNLENLDEKMAVYEAIVSQLQDQGITPAMISVEFIHAPFYRLEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YAF5</accession>
    <name>A0A0P6YAF5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Amidohydro-rel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_06340</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the reversible cyclization of carbamoyl aspartate to dihydroorotate.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the metallo-dependent hydrolases superfamily. DHOase family. Class I DHOase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78832.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062119.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06340"/>
    <dbReference type="EnsemblBacteria" id="KPL78832">
        <property type="protein sequence ID" value="KPL78832"/>
        <property type="gene ID" value="ADN00_06340"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1770"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016812">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in cyclic amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002195">
        <property type="entry name" value="Dihydroorotase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00482">
        <property type="entry name" value="DIHYDROOROTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00483">
        <property type="entry name" value="DIHYDROOROTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="6">
        <location>
            <begin position="2"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010286"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL78832.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="345" mass="38103" checksum="46C083E07A70BD92" modified="2016-01-20" version="1">MKLPGMVDVHVHLRVPGGEHKEDFRTGSAAALAGGITTVLAMPNTFPPIVTIDQLSVAQETANRQSLCDVFMYAGASAEHLNELPRLGEQAPALKLYMDQTYGPLKTNGLENLLRVFESWPKNKVICIHAEQESIAAALGLLNAAPRPIHFCHVSRKAEIELIAAAKRQGLPVTCEVTPHHLFLTEQDATRLGRLGDMRPTLAEQRDVDALWEHINTTIDCIATDHAPHTLQEKQGENPPPGVPGLESSLPLMLTAASQGRLSYERLVEMMHFTPRRIFSLPAQPETWVEIDPDSRYEFPDHPLYTKCGWTPFAGLAMQGRIRQVVLRGKTVVKDGVVLSDVNQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YAV0</accession>
    <name>A0A0P6YAV0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_03845</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03845"/>
    <dbReference type="EnsemblBacteria" id="KPL79033">
        <property type="protein sequence ID" value="KPL79033"/>
        <property type="gene ID" value="ADN00_03845"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070573">
        <property type="term" value="F:metallodipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008257">
        <property type="entry name" value="Pept_M19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10443">
        <property type="entry name" value="PTHR10443"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01244">
        <property type="entry name" value="Peptidase_M19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51365">
        <property type="entry name" value="RENAL_DIPEPTIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="360" mass="40081" checksum="751C724B96359225" modified="2016-01-20" version="1">MLIDGHQDIAWNVMTFGRDYTRSVAETRALEAGTRVPQVNGDTVISWGAYQQGQVALVFATLFATPQQHRWGDWDVHSYASAKEANQIYLRQLDVYQQMAFDHPDKFRLIASQVELKAHLAQWARADEDHPAPVGLLLLMENAEAVQTPDELKMWWDLGVRLIGPAWKTTRLCGGTGSPGPLTAEGYALLEKISELGMILDLSHMDEESVLQALEFYPGVMIASHSNPAAVVNDPASNRHLSDRVIRELIRRDGVMGMVPYNAFLTRGWTRSVARSAVPLERVVDHIDHICDLAGNAWHVALGTDFDGCAGVQDVPDGIDTIADLQKLEDLLAKRGYAEGEIDAIFHENWLRVLFKHLPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YFA2</accession>
    <name>A0A0P6YFA2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Amino acid ABC transporter ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_01150</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000003">
        <property type="protein sequence ID" value="KPL80853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061155.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01150"/>
    <dbReference type="EnsemblBacteria" id="KPL80853">
        <property type="protein sequence ID" value="KPL80853"/>
        <property type="gene ID" value="ADN00_01150"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1975"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015658">
        <property type="term" value="F:branched-chain amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030660">
        <property type="entry name" value="ABC_branched_ATPase_LivF/BraG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039137">
        <property type="entry name" value="ABC_branched_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL80853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="234" mass="25826" checksum="B095CA5BFE3B0101" modified="2016-01-20" version="1">MLEVNDLNVYYGAIHALKGISFHLEEGEIVALIGSNGAGKSSTLNTISGLLRSRTGEIKFQGENISETPPDEIVRRGIIQVPEGRRIFAPLTVTENLEMGAYIHNDRVQIEQDMEEMFNRFPRLRERRKQTGGTLSGGEQQMLAIARGLMARPKLLLLDEPSMGLAPLLVEQIFEIIQDINKRGTSILLVEQNAQMALSIADRGYVLETGKIILEDSADALLENPLVINAYLGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GKL5</accession>
    <name>A0A0N8GKL5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_18400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70034.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064512.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18400"/>
    <dbReference type="EnsemblBacteria" id="KPL70034">
        <property type="protein sequence ID" value="KPL70034"/>
        <property type="gene ID" value="ADN00_18400"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2987"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS" evidence="1">
        <location>
            <begin position="242"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="2">
        <location>
            <begin position="395"/>
            <end position="525"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL70034.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="573" mass="63602" checksum="BFF6AE26FF5BB1AE" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GL14</accession>
    <name>A0A0N8GL14_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">NADH dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_17660</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000042">
        <property type="protein sequence ID" value="KPL71226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064375.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000042.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17660"/>
    <dbReference type="EnsemblBacteria" id="KPL71226">
        <property type="protein sequence ID" value="KPL71226"/>
        <property type="gene ID" value="ADN00_17660"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2798"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.109.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029479">
        <property type="entry name" value="Nitroreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000415">
        <property type="entry name" value="Nitroreductase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00881">
        <property type="entry name" value="Nitroreductase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55469">
        <property type="entry name" value="SSF55469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitroreductase" evidence="2">
        <location>
            <begin position="8"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="domain" description="Nitroreductase" evidence="2">
        <location>
            <begin position="66"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL71226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="172" mass="18978" checksum="D9BD14A7BABE642B" modified="2016-01-20" version="1">MDALEAIFTRRSVRHFSNEAVSEEQLDLLLRAAMQAPSAANGQPWHFVVVNDREMLDAITRFHPFAKALKEAPLAILVCGDARLETAPGRWVQDCSAATENLLLAAHSMGLGAVWLGVQPEPDRIDGLRDLVQLPSGVHPLALVAVGHPKGELPSSAERYRPERVHRNHWSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GLB2</accession>
    <name>A0A0N8GLB2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Carbohydrate kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_16075</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064060.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16075"/>
    <dbReference type="EnsemblBacteria" id="KPL72010">
        <property type="protein sequence ID" value="KPL72010"/>
        <property type="gene ID" value="ADN00_16075"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3650"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000577">
        <property type="entry name" value="Carb_kinase_FGGY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="Carb_kinase_FGGY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018484">
        <property type="entry name" value="Carb_kinase_FGGY_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02782">
        <property type="entry name" value="FGGY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00370">
        <property type="entry name" value="FGGY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000538">
        <property type="entry name" value="GlpK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FGGY_N" evidence="1">
        <location>
            <begin position="7"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="domain" description="FGGY_C" evidence="2">
        <location>
            <begin position="263"/>
            <end position="456"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL72010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="518" mass="57076" checksum="556437DF55CD9B19" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GLC4</accession>
    <name>A0A0N8GLC4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_16690</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72106">
        <property type="protein sequence ID" value="KPL72106"/>
        <property type="gene ID" value="ADN00_16690"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="104" mass="11174" checksum="A421C2AAF47647C3" modified="2016-01-20" version="1" fragment="single">AGLKGVLLAFVFDFPPETGELGIELVSAAGQILTQVSVAAALVRDDRPVPFSFAPQAASGAGPLELRVFARNVDLPVRVLELQHYPLFGLRHVVTQPFAGYLFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GLE1</accession>
    <name>A0A0N8GLE1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_15605</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063959.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72242">
        <property type="protein sequence ID" value="KPL72242"/>
        <property type="gene ID" value="ADN00_15605"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="246"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="414" mass="47907" checksum="58F2DE711F6BDCE3" modified="2016-01-20" version="1">METTITDRKQEVAALTGLTVDQIGAVKFELDHLRKNGLLIDLNISGTSMFIRSTTWIELGIQDIDDPRTSRFTKGSKFLIPEDQIKKLRSIETQMRSLLDGLSFDVTGFRPYRWLPVTAYEKFREKWAELTERFNQAKQEIIDNYDGYRDLVYADFRLIAEAAWKQIEKQGYSYAIVNGKALDRNEFIQAIIQDALAKFPSINQVENDLKCDYVTALLYGQEELEAEKLRTQQLQNLIYEERQKRLALEHDERLRMEREREQLRHEAEINRLAEEEKNAKIMAMWEAELQHAREQLNQISSPLDEVFNDLRRRISGDVESMLESIKKNGYLKGKVAEKGKGLLDLFDLMAAHDDNQLRAKLVELRQAIGPDNKSRADGDVRSTEEIVSILNQIGDLTSKAVKDTMNVSRARFVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GLE2</accession>
    <name>A0A0N8GLE2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_15650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063967.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72250">
        <property type="protein sequence ID" value="KPL72250"/>
        <property type="gene ID" value="ADN00_15650"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="123" mass="13911" checksum="27486F1A34EAAC35" modified="2016-01-20" version="1">MPPASLNTQKLNQVLDQVAELNRTIRGHNGTPGMLTQMAIMSQNLERLTEAVNNINQNGCNYLFRDENRHTPKEQNQQTEQKDEDKFWAFVRDKIAAPVAVALVLGLLSNLPKIILAFDQILK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GM26</accession>
    <name>A0A0N8GM26_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_14055</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063660.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000033.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74122">
        <property type="protein sequence ID" value="KPL74122"/>
        <property type="gene ID" value="ADN00_14055"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL74122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="261" mass="27500" checksum="00DA3CD17838327C" modified="2016-01-20" version="1">MRKQNQKERGQGLLEYALILVAVALGALIILNLFGVSTGELYRTAVNAIGLSPSGGSPSEEAALPGDPPTPSEEEGPLFEDDFSEGLGGWTFLASKFWKGTVTEQDGKMMVGPMGAAFATGFSGTDYTINLSGAELQKKASNNEGFNVIFRSDGATTTFDGYTFSIDKPKNKDAGTLSFYKWENGVQMEQPISSAAVPPGFNWDHPGEIQVRVEGSNFTAAINGQAVLTGSDSTYPQGGVGLSSNFGSYLLVDGVSIQSAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GM52</accession>
    <name>A0A0N8GM52_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063567.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000032.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74330">
        <property type="protein sequence ID" value="KPL74330"/>
        <property type="gene ID" value="ADN00_13580"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="231" mass="26520" checksum="E6734BB0DBCE0931" modified="2016-01-20" version="1">MKIVTNEKYVVRNQKIGKYFLWASLAILGVGLYMSFQPSLMLYSYIALLVGFVTSQVSVFYTNRIGVKSRVDHKISAALKGLDNKFTLYHFATPVSHLLVGPAGIWIIMPYHQAGTITYDEKRNRWKQKGGNFFMKLFAQESIGRPDYEVKTAIEDLERYLTQKLNLQEHPPVKAILAFYNPKAETQAENAPHPTVLLEKAKDYFRRVTKENPVNMEEIKSIQNLLPDSEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMB3</accession>
    <name>A0A0N8GMB3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peripla_BP_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13305</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74818.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74818">
        <property type="protein sequence ID" value="KPL74818"/>
        <property type="gene ID" value="ADN00_13305"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peripla_BP_3" evidence="1">
        <location>
            <begin position="133"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74818.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="286" mass="30245" checksum="42AC2CF68F104A75" modified="2016-01-20" version="1">MDAVRELNYLPDVAAQGLSQQKTWLLGVALPDLTKAFYAQVFRGIQRAAAEAGYDLIVAEVSPVAGDLNAASERMLRRKVDGAIVPAQGLAEETISRLRDAGVKVVVLGAGGKTEGVCQVVWDEEEGVRQMIAHLLSHGHRKVAFAGGAEKDEETRRIRQAFLNSLRELGQTALAGMLSEEDLAAHLEALFQGAEKPTAVFCANGALAMKVIWRLEALGCRVPGDVAVAGFGSCGETAPALTTFDPDPTAVGKAAATCLVEWLKEGADDTARSIHVGGRLVIGETT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GN20</accession>
    <name>A0A0N8GN20_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09740</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76874">
        <property type="protein sequence ID" value="KPL76874"/>
        <property type="gene ID" value="ADN00_09740"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="89" mass="9725" checksum="8571032E7F1C3220" modified="2016-01-20" version="1">MGGLEVAARLFQPAHPRRGRAVKVGHVGFDVEQGRAVQNIEVGNLQNVRLDADQLNDGDPNRVGARVANSPRAADSRKGVTVKVTWRDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNC2</accession>
    <name>A0A0N8GNC2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">SufBD protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_08770</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000022">
        <property type="protein sequence ID" value="KPL77690.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08770"/>
    <dbReference type="EnsemblBacteria" id="KPL77690">
        <property type="protein sequence ID" value="KPL77690"/>
        <property type="gene ID" value="ADN00_08770"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1472"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000825">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037284">
        <property type="entry name" value="SUF_FeS_clus_asmbl_SufBD_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01458">
        <property type="entry name" value="SUFBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101960">
        <property type="entry name" value="SSF101960"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL77690.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="376" mass="40100" checksum="3B620DC186C9780E" modified="2016-01-20" version="1">MDDLPLVSLDGLQGSDSASLAEVGVITNEAQRAGSFVMRNSHTLCSYAHVDGLEVLPIHQALEKYDWLGEKYYWKLVKRDADDVTRHVAAQSQPQGFFIRVMPGVKVELPYQAGLYMAEANSAQTLHNVVIVEEGAELTLITGCTTHQGVEEGLHLAVSEFYIGKQATLTNNMVHAWGPKVTVRPKAGTAVAAGGCYNSNYISLRPAADIITNPVTWLNGEGATARFQSIVLGAPGSFIQSGGEVYLNGLNSSTELIHRAVCTGGQILQEGLLVGSNACRAHIDCSGMLLNAGDEGFIQSNPGLRALNPDAQMSHEASIGKIAPDQVEYLMARGIGERDAISMIIRGFLQADIEGLGAELDARIAEIANLADLAEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNL5</accession>
    <name>A0A0N8GNL5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">3-hydroxy-3-methylglutaryl coenzyme A reductase</fullName>
            <shortName evidence="3">HMG-CoA reductase</shortName>
            <ecNumber evidence="3">1.1.1.88</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_06845</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>(R)-mevalonate + CoA + 2 NAD(+) = (3S)-hydroxy-3-methylglutaryl-CoA + 2 H(+) + 2 NADH</text>
            <dbReference type="Rhea" id="RHEA:14833"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:36464"/>
            <dbReference type="ChEBI" id="CHEBI:43074"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="EC" id="1.1.1.88"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Metabolic intermediate metabolism; (R)-mevalonate degradation; (S)-3-hydroxy-3-methylglutaryl-CoA from (R)-mevalonate: step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the HMG-CoA reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.88" evidence="3"/>
    <dbReference type="EMBL" id="LGCL01000018">
        <property type="protein sequence ID" value="KPL78434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062236.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000018.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06845"/>
    <dbReference type="EnsemblBacteria" id="KPL78434">
        <property type="protein sequence ID" value="KPL78434"/>
        <property type="gene ID" value="ADN00_06845"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2285"/>
    <dbReference type="UniPathway" id="UPA00257">
        <property type="reaction ID" value="UER00367"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140643">
        <property type="term" value="F:hydroxymethylglutaryl-CoA reductase (NADH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004420">
        <property type="term" value="F:hydroxymethylglutaryl-CoA reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015936">
        <property type="term" value="P:coenzyme A metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00644">
        <property type="entry name" value="HMG-CoA_reductase_classII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.770.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002202">
        <property type="entry name" value="HMG_CoA_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004553">
        <property type="entry name" value="HMG_CoA_Rdtase_bac-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023074">
        <property type="entry name" value="HMG_CoA_Rdtase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023076">
        <property type="entry name" value="HMG_CoA_Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009023">
        <property type="entry name" value="HMG_CoA_Rdtase_NAD(P)-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009029">
        <property type="entry name" value="HMG_CoA_Rdtase_sub-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10572">
        <property type="entry name" value="PTHR10572"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00368">
        <property type="entry name" value="HMG-CoA_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00071">
        <property type="entry name" value="HMGCOARDTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55035">
        <property type="entry name" value="SSF55035"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56542">
        <property type="entry name" value="SSF56542"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00532">
        <property type="entry name" value="HMG_CoA_R_NAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00066">
        <property type="entry name" value="HMG_COA_REDUCTASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00318">
        <property type="entry name" value="HMG_COA_REDUCTASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01192">
        <property type="entry name" value="HMG_COA_REDUCTASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50065">
        <property type="entry name" value="HMG_COA_REDUCTASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0520">NAD</keyword>
    <keyword evidence="2 3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU361219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL78434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="431" mass="46051" checksum="178A58C56D4ABF60" modified="2016-01-20" version="1">MPSKARNSGAVKFYNLSVEERLRVLADESGLQEGALQAFTAQGGLNVEQADHMIENVAGLHALPLGIARNFIVNGREVLVPMAIEEPSVVAGASFMAKLARPAGGFFTHADPPHMIGQMQILDTVHPQEARLRLLEQKERLLDDVREIDPLLKKLGGGPRDLQVRVIEDSPIGPFLVAHLIYDVRDAMGANAVNTAVERIAPAVEAITGGRVLLRILSNLADQRLARARCTIRLADLGFDAFTPEEVRDGIIAAWAFAAADPYRAATHNKGIMNGVDAVVLATGNDWRAVEAGGHAYAARAGRYTSLSTWGKDAEGNLIGTLEMPMAVGLVGGATKVHPTAQAALKLMGVQTAAELAQIIAAVGLAQNLAALRALATEGIQRGHMSLHARQVAIAAGAPAELVEKLAQQLVQEKTVRIDRAEEILRAWQNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNX8</accession>
    <name>A0A0N8GNX8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">dITP/XTP pyrophosphatase</fullName>
            <ecNumber evidence="6">3.6.1.66</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Non-canonical purine NTP pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Non-standard purine NTP pyrophosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Nucleoside-triphosphate diphosphatase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Nucleoside-triphosphate pyrophosphatase</fullName>
            <shortName evidence="6">NTPase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_03150</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>H2O + ITP = diphosphate + H(+) + IMP</text>
            <dbReference type="Rhea" id="RHEA:29399"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="ChEBI" id="CHEBI:61402"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>H2O + XTP = diphosphate + H(+) + XMP</text>
            <dbReference type="Rhea" id="RHEA:28610"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57464"/>
            <dbReference type="ChEBI" id="CHEBI:61314"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>dITP + H2O = dIMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:28342"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61194"/>
            <dbReference type="ChEBI" id="CHEBI:61382"/>
            <dbReference type="EC" id="3.6.1.66"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="6">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the HAM1 NTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.66" evidence="6"/>
    <dbReference type="EMBL" id="LGCL01000014">
        <property type="protein sequence ID" value="KPL79338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061507.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000014.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03150"/>
    <dbReference type="EnsemblBacteria" id="KPL79338">
        <property type="protein sequence ID" value="KPL79338"/>
        <property type="gene ID" value="ADN00_03150"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2042"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035870">
        <property type="term" value="F:dITP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036220">
        <property type="term" value="F:ITP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017111">
        <property type="term" value="F:nucleoside-triphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036222">
        <property type="term" value="F:XTP diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009146">
        <property type="term" value="P:purine nucleoside triphosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00515">
        <property type="entry name" value="HAM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01405">
        <property type="entry name" value="Non_canon_purine_NTPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020922">
        <property type="entry name" value="dITP/XTP_pyrophosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002637">
        <property type="entry name" value="Ham1p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11067">
        <property type="entry name" value="PTHR11067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01725">
        <property type="entry name" value="Ham1p_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52972">
        <property type="entry name" value="SSF52972"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00042">
        <property type="entry name" value="TIGR00042"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="9"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="156"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="184"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="73"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="179"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL79338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="202" mass="22029" checksum="DA46EBFAF9D91E3B" modified="2016-01-20" version="1">MPTPLLIATSNPGKLRELQALLVDLHDQIQLLLPADLNLSLEVVEDGDTYLENAVKKALAYGQASGLLTLADDSGLEVDALNGAPGLFSARYSDKPGATDVDRRIHLLDNLHFHPRPWTARFRCLVALASPNGELRHSEGICPGEIIPEERGNNGFGYDPIFLLSERGKTIAELSMAEKNTLSHRARAVHAAIPLIQELISR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WMN1</accession>
    <name>A0A0P6WMN1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptide chain release factor 1</fullName>
            <shortName evidence="5">RF-1</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">prfA</name>
        <name evidence="9" type="ORF">ADN00_18500</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 5">Peptide chain release factor 1 directs the termination of translation in response to the peptide chain termination codons UAG and UAA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="5">Methylated by PrmC. Methylation increases the termination efficiency of RF1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the prokaryotic/mitochondrial release factor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064526.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18500"/>
    <dbReference type="EnsemblBacteria" id="KPL70048">
        <property type="protein sequence ID" value="KPL70048"/>
        <property type="gene ID" value="ADN00_18500"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3008"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016149">
        <property type="term" value="F:translation release factor activity, codon specific"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00093">
        <property type="entry name" value="Rel_fac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005139">
        <property type="entry name" value="PCRF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000352">
        <property type="entry name" value="Pep_chain_release_fac_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045853">
        <property type="entry name" value="Pep_chain_release_fac_I_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004373">
        <property type="entry name" value="RF-1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03462">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00472">
        <property type="entry name" value="RF-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00937">
        <property type="entry name" value="PCRF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75620">
        <property type="entry name" value="SSF75620"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00019">
        <property type="entry name" value="prfA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0488">Methylation</keyword>
    <keyword evidence="4 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PCRF" evidence="8">
        <location>
            <begin position="61"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="280"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="5"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="280"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="modified residue" description="N5-methylglutamine" evidence="5">
        <location>
            <position position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002986"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL70048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="355" mass="40497" checksum="D1A39E0C07B537F9" modified="2016-01-20" version="1">MLEKLQGIENRYEELTRLMGESAEDYQVMVEYAKERADLEPVVNKAREYRQTIKHIEEARELAQSEDGEMRDLALLDLEELSPKAEQLEKEIKGMLVPKDPRDDRNVIMEIRAGTGGDEAALFAADLFRMYSYYAENRRWKIEIISENETGIGGLKEVIFLVKGRGAYSRLKFESGVHRVQRIPATETQGRVHTSTVTVAVLAEVEDVEIDIPENDIKIDVYKSAGAGGQNVQKNSTAVRITHFPTGLVVACQDERSQLQNRLRALSILRARLYDMELEKQQKEREDARRSQVGTGERSEKIRTYNYPQSRVTDHRVNISSYNLPAVMNGAIDEFIDELSLREESDRLASIGEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WMR0</accession>
    <name>A0A0P6WMR0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_18755</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064569.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18755"/>
    <dbReference type="EnsemblBacteria" id="KPL70085">
        <property type="protein sequence ID" value="KPL70085"/>
        <property type="gene ID" value="ADN00_18755"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="274" mass="32521" checksum="3A6B6B1F0B7F76F9" modified="2016-01-20" version="1">MSIYHYEKLLILTKTYPSPSLKYRETSCVAALNQKGEMRRIFPVPFRLLDGQQQFQRWEWIKARVAKATGDNRPESYRIDVDSIQRLSKIGTENAWAERIQWISPHMICSFDAIEARRQATGETLGFIRPSKVNLIIKKSDQPDWTPEENEKLIKDGLFDSEEVRQRNPLRKVPYDFYYTYESFSDGSLPIEYTHKITDWEVCALYWRCIRDYGNDWEIAFRNKLQDEFSQTKDLIFLMGTMHRFRDKWLIVGLIYPPKVEARQQALFLPCPND</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WPM5</accession>
    <name>A0A0P6WPM5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_16115</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064068.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72017">
        <property type="protein sequence ID" value="KPL72017"/>
        <property type="gene ID" value="ADN00_16115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="53"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="385" mass="42634" checksum="64D724482EC1CEF8" modified="2016-01-20" version="1">MAKVFTLLIALAGLVIIAFGGCVRPAAPLQQISPIEPAIMSANPIGSASATNSCTPFLPRSPTPTATFTPILSPTATPTSAPIPASPASPRPVRTSPAPPSTLPEDQESQPHPTDDQGSLHPHPFYGMEFVPTKDFETVRGLGIEVIGQTFAHDGSPASWKAQLDLAEDAGLRVIAWLWPQGWTWEGDQWVIDEQARSFLETVAGNEALFAVYVFNEPYWQECWGCGYTTSQQQKLYSQIKAIRNVPIFSAVDSMRFWTDYSPETAFADGICDYCATWYYPVTQDGFDQDELRARIAADLSTARQRAPKSKIVWYMQAFAGAESGYRVPTANEMEEIARIVYEAGVDGAMWYVWSFNSLYNDTLCRHPELFATVRKIYEETVLLH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WXP2</accession>
    <name>A0A0P6WXP2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosomal protein L11 methyltransferase</fullName>
            <shortName evidence="2">L11 Mtase</shortName>
            <ecNumber evidence="2">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="primary">prmA</name>
        <name evidence="3" type="ORF">ADN00_17635</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Methylates ribosomal protein L11.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>L-lysyl-[protein] + 3 S-adenosyl-L-methionine = 3 H(+) + N(6),N(6),N(6)-trimethyl-L-lysyl-[protein] + 3 S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:54192"/>
            <dbReference type="Rhea" id="RHEA-COMP:9752"/>
            <dbReference type="Rhea" id="RHEA-COMP:13826"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29969"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:61961"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the methyltransferase superfamily. PrmA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="2"/>
    <dbReference type="EMBL" id="LGCL01000042">
        <property type="protein sequence ID" value="KPL71221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064370.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000042.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17635"/>
    <dbReference type="EnsemblBacteria" id="KPL71221">
        <property type="protein sequence ID" value="KPL71221"/>
        <property type="gene ID" value="ADN00_17635"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2791"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008276">
        <property type="term" value="F:protein methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00735">
        <property type="entry name" value="Methyltr_PrmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004498">
        <property type="entry name" value="Ribosomal_PrmA_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000401">
        <property type="entry name" value="RPL11_MTase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00406">
        <property type="entry name" value="prmA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="binding site" evidence="2">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="171"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="193"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="241"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00735"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL71221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="305" mass="33245" checksum="2DA271A130672875" modified="2016-01-20" version="1">MEAKAYWIEISLTVDGELAEALAEAISRYVVNGVVVESEAVSQPDNAEGIPSTIAKVYGYIPVDDKLEETRQKIEEALWYLGRIQPLPQPVYRKIEEQNWMAAWKTRYHPIPVGERLLVLPAWMEQTDPSRVAIRIDPSMAFGTGTHPSTQLCLQMTDQYTQAGQRAIDVGCGSGILSIGAALLGASQVLSVDIDPESVKATRENAEANGVLEKLEIGAGSVTEVRRGDFSFNQAPLVLVNILAPIILQLFNDGLADLVAPGGKLVMAGILEPQARGVEEAAEARGLRKINHGQINDWVCLVYEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WY04</accession>
    <name>A0A0P6WY04_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FliH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_17060</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71404.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064258.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17060"/>
    <dbReference type="EnsemblBacteria" id="KPL71404">
        <property type="protein sequence ID" value="KPL71404"/>
        <property type="gene ID" value="ADN00_17060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018035">
        <property type="entry name" value="Flagellar_FliH/T3SS_HrpE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02108">
        <property type="entry name" value="FliH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="FliH" evidence="4">
        <location>
            <begin position="169"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="78"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="104"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL71404.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="300" mass="33090" checksum="2F8A0956AE2F88D5" modified="2016-01-20" version="1">MNLSHNPQVTVWQFEEIEKAESGIPTSAFNEVLEALVGGGQPGKKRFSRAGQCLIKQTEAEDISNWLFQDIRALKEDRPSHPAAKPMPVEPRPSRPNITSGSILDKARQDAQQILEQAQAEAEQLLQKAQEEVDLFLAEASDQVAAARQEGYLEGKQAAEEEMTSLLAVVRDLVEETRDWQDALLRQSEPIIVGLIKTIAAKLFGEGIALDPQTLQQTLTRAVEKARTLGELQIYMHPADAASLDPYWREFQSTLIGSPIKILSSDSILRGGCYINGKSGSVDMRIETQLNTVLDALNMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WY28</accession>
    <name>A0A0P6WY28_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Probable chemoreceptor glutamine deamidase CheD</fullName>
            <ecNumber evidence="3">3.5.1.44</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">cheD</name>
        <name evidence="4" type="ORF">ADN00_17285</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Probably deamidates glutamine residues to glutamate on methyl-accepting chemotaxis receptors (MCPs), playing an important role in chemotaxis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>H2O + L-glutaminyl-[protein] = L-glutamyl-[protein] + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:16441"/>
            <dbReference type="Rhea" id="RHEA-COMP:10207"/>
            <dbReference type="Rhea" id="RHEA-COMP:10208"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:29973"/>
            <dbReference type="ChEBI" id="CHEBI:30011"/>
            <dbReference type="EC" id="3.5.1.44"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the CheD family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.44" evidence="3"/>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064301.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17285"/>
    <dbReference type="EnsemblBacteria" id="KPL71440">
        <property type="protein sequence ID" value="KPL71440"/>
        <property type="gene ID" value="ADN00_17285"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.520"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050568">
        <property type="term" value="F:protein-glutamine glutaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16352">
        <property type="entry name" value="CheD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01440">
        <property type="entry name" value="CheD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038592">
        <property type="entry name" value="CheD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005659">
        <property type="entry name" value="Chemorcpt_Glu_NH3ase_CheD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011324">
        <property type="entry name" value="Cytotoxic_necrot_fac-like_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35147">
        <property type="entry name" value="PTHR35147"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03975">
        <property type="entry name" value="CheD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64438">
        <property type="entry name" value="SSF64438"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="2 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01440"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL71440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="163" mass="17069" checksum="89DD2555F34E7BE7" modified="2016-01-20" version="1">MENSVSVGLGEIAISRNPDEVLVAYGLGSCLGIGVYDPVARVAGLLHAVLPESPNGSSANGSAAKYVNTGIVELMKGLEAAGGSPARAKIRVIGGANMLLSSSLSKTFDIGTRNIEASRKTFEKMRLKVSAEEVGGHTGRTVRLFVHNGRMTFRIVGGKEQEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZF1</accession>
    <name>A0A0P6WZF1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">30S ribosomal protein S6</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpsF</name>
        <name evidence="6" type="ORF">ADN00_15095</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Binds together with S18 to 16S ribosomal RNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the bacterial ribosomal protein bS6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063868.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15095"/>
    <dbReference type="EnsemblBacteria" id="KPL72159">
        <property type="protein sequence ID" value="KPL72159"/>
        <property type="gene ID" value="ADN00_15095"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.721"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00473">
        <property type="entry name" value="bS6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00360">
        <property type="entry name" value="Ribosomal_S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000529">
        <property type="entry name" value="Ribosomal_S6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020814">
        <property type="entry name" value="Ribosomal_S6_plastid/chlpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035980">
        <property type="entry name" value="Ribosomal_S6_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014717">
        <property type="entry name" value="Transl_elong_EF1B/ribosomal_S6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21011">
        <property type="entry name" value="PTHR21011"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01250">
        <property type="entry name" value="Ribosomal_S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54995">
        <property type="entry name" value="SSF54995"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00166">
        <property type="entry name" value="S6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009512"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00016787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL72159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="94" mass="10822" checksum="EFF24F2EA2D1CACB" modified="2016-01-20" version="1">MRKYELVFIVHPDLDETAFGGIVEKVTGWVTESGGSVEKTDVWGKRRMAYAIRKQREGQYVLMNVNIAPSFTAELERNLQILEPVMRFMLTEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZL5</accession>
    <name>A0A0P6WZL5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_15750</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72269.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72269">
        <property type="protein sequence ID" value="KPL72269"/>
        <property type="gene ID" value="ADN00_15750"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="481"/>
            <end position="506"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72269.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="506" mass="57622" checksum="096433A4F4E85CD5" modified="2016-01-20" version="1">MAGEADFNSFEARKFRYDLYWSYYENTAYSKIHAWARIFKSNYGLYKAIRGIYNPAYRLGEFWKTHLWGGPLDPFARNDESTATPIQTQNEDLRGALAQVWRWSNWQTNKNICALWGTVLGDVAIKVIDDVQKRKVFFEIIHPGTIKSVDLDKMGNVKGYVIEQELKDPENLNRFVVYREVASRNGDEVVYELFKNDAPYAWGNEAHTWSEPYGFVPMVFIRHNNVGLNFGFSEYQGGHAKFREVDDVASKLSDQIRKMVDAPWLFSGVSKPTSKARTAYTEASDQNELPIREETPVFYGPVGSSAYPLVSNLNISDTAAYVKDLLEILEKDYPELNSDLLNVKGDISGRALRVNQRPTENKVRDRRVNYDDALVRAQMMAVAIGGFRHYDGFEGFDLESYDKGDLDHSIADRPVFQEDKADELELEQTFWNVAKSAKSNGMPLPLFLERHGWSDEDILKITNSEEYKARLEAFKQIAALSEGSEEGETEIGEVGQAGDGSQSEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X1J1</accession>
    <name>A0A0P6X1J1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_15010</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000036">
        <property type="protein sequence ID" value="KPL73095.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063848.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000036.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15010"/>
    <dbReference type="EnsemblBacteria" id="KPL73095">
        <property type="protein sequence ID" value="KPL73095"/>
        <property type="gene ID" value="ADN00_15010"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015293">
        <property type="term" value="F:symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008643">
        <property type="term" value="P:carbohydrate transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039672">
        <property type="entry name" value="MFS_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001927">
        <property type="entry name" value="Na/Gal_symport"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018043">
        <property type="entry name" value="Na/Gal_symport_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11328">
        <property type="entry name" value="PTHR11328"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00792">
        <property type="entry name" value="gph"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00872">
        <property type="entry name" value="NA_GALACTOSIDE_SYMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="119"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="165"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="195"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="254"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="288"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="326"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="352"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="399"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="441"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="480"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL73095.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="500" mass="56115" checksum="C52D6D7D66FBFEBB" modified="2016-01-20" version="1">MQADSSTTTLTEAPLEKLPLFQRVIYGTGDWGRASFNTLRQFFYAIFLTDVVGLDPRLASFAALISIIWDAINDPIIGAVSDNVRTRWGRRRPFLLVFAVPFALAFLLLWWAPPWQTQAMLMIHVTLAYMVSDTIQTLITVPYLALTPELAPTYDGRTSLTSMRMFFNLVASLVTAVAAPSIMDGALHAGLSQQQAYMTIAAIFGGAAILPYLVIFFIVKEKQPSENIQTETYTFRGTLKLLWQNTPFKFATGIYVLNWIAFDIEGLMLPFFLLYIVAQGNLLAKVDFFGASIALESVVFGVLLLVATLSIPIWNRLAHRFSKRSAYIIGMAFWIVVQLFVFSIQAGQIQLIIVLAALAGLSVSTAHIMPEAIFPDVIDWDELRTNKRHEGMYYGAINFIRKLSSAIATFIALQALGWFGYQSPPANTTTFLQPAQAVNAIRFITGPVIIILLLFAILFAWKYPLSRERQKKIRTMLNRRKNRKAARLQPTVSRDMTPKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X216</accession>
    <name>A0A0P6X216_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Hemerythrin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_11355</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the hemerythrin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063131.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76552">
        <property type="protein sequence ID" value="KPL76552"/>
        <property type="gene ID" value="ADN00_11355"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12107">
        <property type="entry name" value="Hemerythrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016131">
        <property type="entry name" value="Haemerythrin_Fe_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012312">
        <property type="entry name" value="Hemerythrin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035938">
        <property type="entry name" value="Hemerythrin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012827">
        <property type="entry name" value="Hemerythrin_metal-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01814">
        <property type="entry name" value="Hemerythrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47188">
        <property type="entry name" value="SSF47188"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02481">
        <property type="entry name" value="hemeryth_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00550">
        <property type="entry name" value="HEMERYTHRINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hemerythrin" evidence="5">
        <location>
            <begin position="14"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="7"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL76552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="135" mass="16147" checksum="CCC7411B1E4D13CD" modified="2016-01-20" version="1">MPIMKWMDEYSVQVAELDQQHQKLIELINLLHDEMRQGKGRESLGRILDQLIEYTRVHFTTEEDWMARAGYAGLAAHREEHRALTRQVEELQDQHRAGSRTLSLEVMVFLKDWLVNHIQKTDQKYSDVLKEYQRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X254</accession>
    <name>A0A0P6X254_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Cysteine synthase</fullName>
            <ecNumber evidence="4 10">2.5.1.47</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">ADN00_14695</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>hydrogen sulfide + O-acetyl-L-serine = acetate + L-cysteine</text>
            <dbReference type="Rhea" id="RHEA:14829"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:58340"/>
            <dbReference type="EC" id="2.5.1.47"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 8 10">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the cysteine synthase/cystathionine beta-synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.47" evidence="4 10"/>
    <dbReference type="EMBL" id="LGCL01000035">
        <property type="protein sequence ID" value="KPL73585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063786.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000035.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14695"/>
    <dbReference type="EnsemblBacteria" id="KPL73585">
        <property type="protein sequence ID" value="KPL73585"/>
        <property type="gene ID" value="ADN00_14695"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2105"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004124">
        <property type="term" value="F:cysteine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005856">
        <property type="entry name" value="Cys_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005859">
        <property type="entry name" value="CysK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001216">
        <property type="entry name" value="P-phosphate_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01139">
        <property type="entry name" value="cysK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01136">
        <property type="entry name" value="cysKM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00901">
        <property type="entry name" value="CYS_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7 10" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="6 8 10" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PALP" evidence="11">
        <location>
            <begin position="7"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="8">
        <location>
            <begin position="178"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="74"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="266"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="9">
        <location>
            <position position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000298"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR605856-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR605856-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KPL73585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="311" mass="32927" checksum="7F2210194BF9A71B" modified="2016-01-20" version="1">MRIANNVTDLIGNTPLVKLNRITEGALADVVVKLEYFNPGKSVKDRIALAMIEDAERKGLIHKDTVIVEPTSGNTGIGLAMVCAARGYRCVITMPESMSRERRVLLRAFGAELILTPASAGMAGAIAKAEELAANDPNVFIPMQFDNPANPQVHRLTTAEEIWRDTDGKVDIVVSGVGTGGTITGVGERLKELKPSVKMVAVEPAASPVLSGGQKGPHPIQGIGAGFVPAVLNTGIYDEIIQVTGEDTFATSRAMATQEGLLVGISSGAATWAALQLARRPENAGKLIVVIIPSFGERYLTTALYEGLDRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X2R8</accession>
    <name>A0A0P6X2R8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_10535</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the pirin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77000.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062959.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10535"/>
    <dbReference type="EnsemblBacteria" id="KPL77000">
        <property type="protein sequence ID" value="KPL77000"/>
        <property type="gene ID" value="ADN00_10535"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2578"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012093">
        <property type="entry name" value="Pirin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003829">
        <property type="entry name" value="Pirin_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041602">
        <property type="entry name" value="Quercetinase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43212">
        <property type="entry name" value="PTHR43212"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02678">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17954">
        <property type="entry name" value="Pirin_C_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006232">
        <property type="entry name" value="Pirin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pirin" evidence="3">
        <location>
            <begin position="10"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="domain" description="Pirin_C_2" evidence="4">
        <location>
            <begin position="146"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF17954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL77000.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="248" mass="28075" checksum="D1010CADB51218E3" modified="2016-01-20" version="1">MIQRIPAEKRHFSDFGWLKTYWLFSFSNYYDPNNIQFGPLRVFNDDVVLPGYGFPTHPHREMEIITLVLSGEITHEDSMGNRNVICAGDVQRMSAGVGVTHSEFNLSEHSTRFYQVWIYPDVPALTPSYDQRTFQPAQWKNCLLPVASGVGMENVVTFNANATIYRAELDGHHAIELASNDHRRTFLYLTAGRLCVNGVTLHSNDQARIDLESEIKIAAEEDSSFVLLDLPSCKGWGYDEKTLKGTPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X308</accession>
    <name>A0A0P6X308_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_14020</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063653.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000033.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14020"/>
    <dbReference type="EnsemblBacteria" id="KPL74116">
        <property type="protein sequence ID" value="KPL74116"/>
        <property type="gene ID" value="ADN00_14020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1904"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL74116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="142" mass="15552" checksum="6CB7F065F5A3F03B" modified="2016-01-20" version="1">MDHVVYVDAKSKELEKILDGSKTMIIRGAAGRKLPHGRVSAGDVLYFIQNNGEGQVRARAVVAAALHSEKLSPAEAEQLVRENQDKLQLSPALAARWASKRYLVLVEIHPAEALQPFAIDRSAYGNMDDWLPVGDIAAVRLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X362</accession>
    <name>A0A0P6X362_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77275.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77275">
        <property type="protein sequence ID" value="KPL77275"/>
        <property type="gene ID" value="ADN00_09055"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="147"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="219"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77275.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="261" mass="29127" checksum="D3C2625E8D5E4F10" modified="2016-01-20" version="1">MQETLKQIFTFHWNPNKDLIAVAVTVLLVMGGISIATNINGQQDRGGIPYFIVYAVITAALCGVALPLYWTVFIRHRSLESLGMTRKWLRRSHFIQLIFVILQFAGIMGKVQFPPLAQLLPLIGLAMFIGFFETVFWRGWVQTRLEAAFGILPSVVLSAALYALHYLAYGASLVDLLSLFLAGLLYSIVFRLTSNVLIIWPVFLPMRILISLINDGRTISMPAVLGLFGVWLLMLGLVRVAGQYHQTHTQLPITILPVGSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-04-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X3V5</accession>
    <name>A0A0P6X3V5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_11750</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063208.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76028">
        <property type="protein sequence ID" value="KPL76028"/>
        <property type="gene ID" value="ADN00_11750"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="272"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="320"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="367"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="415"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="441"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="496"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="729"/>
            <end position="749"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="780"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="827"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="19"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="302"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="496"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="761"/>
            <end position="852"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL76028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="861" mass="93772" checksum="7E5EB6D7695AAA29" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X3W2</accession>
    <name>A0A0P6X3W2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_13935</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13935"/>
    <dbReference type="EnsemblBacteria" id="KPL74101">
        <property type="protein sequence ID" value="KPL74101"/>
        <property type="gene ID" value="ADN00_13935"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL74101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="630" mass="68265" checksum="92E32ACE58A016F1" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X3Z4</accession>
    <name>A0A0P6X3Z4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_12275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76110.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063307.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76110">
        <property type="protein sequence ID" value="KPL76110"/>
        <property type="gene ID" value="ADN00_12275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="189"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="212"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="289"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="315"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="343"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="374"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="471"/>
            <end position="492"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76110.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="524" mass="60151" checksum="F2337088AA0D0CF7" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X400</accession>
    <name>A0A0P6X400_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_14210</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063687.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000033.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74147">
        <property type="protein sequence ID" value="KPL74147"/>
        <property type="gene ID" value="ADN00_14210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="9"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="35"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="179"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL74147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="353" mass="40715" checksum="417BF705864C944F" modified="2016-01-20" version="1">MTINSKKAWGFLIFFIVLSISVFLIQAISNDLSNVLLVFFEFLKFVFAICIGLFIELLLSEESYQQEIQRVVVSAYRRISDIGKSISSMQEDIDQLIHRYPTNKLHEIETIKVRADEIANNVASSEDDWIDFLKKDIKALEEIEKRKKQIQKISNYSHKYTIQTSPIRQLEEFPEISNNVIDEKMIKSSEQRIEELRSEINALIESLPVAVRTLIDEEPLPRGGKKSEFVYQYLFHYAKENGFIRIPINVGSDINNRKIEITAMKPYRFLLQTACGTEIMTIAGNNHDAIGVVENPFPNIYYKDYFFTLIDFLKLSTVEEYMPVIPNSELDDTLAGTGIVFIKVKIQVEQSIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X4I6</accession>
    <name>A0A0P6X4I6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Oxygen sensor histidine kinase NreB</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Nitrogen regulation protein B</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">ADN00_13640</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Member of the two-component regulatory system NreB/NreC involved in the control of dissimilatory nitrate/nitrite reduction in response to oxygen. NreB functions as a direct oxygen sensor histidine kinase which is autophosphorylated, in the absence of oxygen, probably at the conserved histidine residue, and transfers its phosphate group probably to a conserved aspartate residue of NreC. NreB/NreC activates the expression of the nitrate (narGHJI) and nitrite (nir) reductase operons, as well as the putative nitrate transporter gene narT.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063578.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000032.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13640"/>
    <dbReference type="EnsemblBacteria" id="KPL74339">
        <property type="protein sequence ID" value="KPL74339"/>
        <property type="gene ID" value="ADN00_13640"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="11" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0408">Iron</keyword>
    <keyword evidence="8" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Histidine kinase" evidence="12">
        <location>
            <begin position="156"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="23"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="11">
        <location>
            <begin position="87"/>
            <end position="114"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00017322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00024827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030800"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KPL74339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="346" mass="38876" checksum="7072CF9472FA136C" modified="2016-01-20" version="1">MGLLNQSEPNPWEDFKQFISSELQESKRALNEITLMLEQSQAELAKLTQRNAVITGHVQQIIGQLEAIPRSDIVSAYNASLDAQQRLLVMRTQLEKLQSERAGLQKLVEVLQRTQEIFGADLTGIAKGGNGTALLEMLIDGQESIRQRLSRQMHDGPAQTLSNFIVQTEIAARLLEIDPNRAKEELNNLKVAAMSTFQKVRGFIFELRPMMLDDLGLIPTLKRYVDTFKEQTGCDVQLAIKGRERRLESYMEVMIFRALQELIGNAEKHNQDMPMKVRIEVELSIEENFVRASVSDNGKGFHEGVLNETSGMGLKFIKQRVELMGGVMELDSGPTKGARIALQIPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X4Y1</accession>
    <name>A0A0P6X4Y1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09605</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76851.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062785.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09605"/>
    <dbReference type="EnsemblBacteria" id="KPL76851">
        <property type="protein sequence ID" value="KPL76851"/>
        <property type="gene ID" value="ADN00_09605"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004360">
        <property type="entry name" value="Glyas_Fos-R_dOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00903">
        <property type="entry name" value="Glyoxalase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="2"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76851.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="122" mass="13284" checksum="3812E6BA4DC17E4E" modified="2016-01-20" version="1">MKFLWTTIYVTHLDESIAFYTELVGLKLLRRFAAGPGMELAFLGNGVEGETTVELLADSSQSAVQHGDFVSLGFAVESLDAMLETVKSKNIPVHSGPIETPASKFFTVKDPNGLSVQFFQAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X4Y4</accession>
    <name>A0A0P6X4Y4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09660</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062795.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76860">
        <property type="protein sequence ID" value="KPL76860"/>
        <property type="gene ID" value="ADN00_09660"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="22"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="107"/>
            <end position="123"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="132" mass="14082" checksum="6A2321D0C9670B40" modified="2016-01-20" version="1">MTASHPPEPENQNQPPIERSKAFASLVTILTASGILGVLAGLIHLLGAMASGFTPVSAADVIFNIIFGGMIFFCSRVLARGKALVIWLALGCVALSILYSFVLGRGFNYVIATVGALFIWQLFKLKQQGELS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X4Y9</accession>
    <name>A0A0P6X4Y9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09710</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76869.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062805.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76869">
        <property type="protein sequence ID" value="KPL76869"/>
        <property type="gene ID" value="ADN00_09710"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2399"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042150">
        <property type="entry name" value="MmRce1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35797">
        <property type="entry name" value="PTHR35797"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="25"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="169"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="207"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="234"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="261"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76869.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="292" mass="31723" checksum="2BBEE9490341E9B9" modified="2016-01-20" version="1">MQPAPETSSPSSSGKIKLMLRQHPLLAFFILAYAISWILSIPFILAEWGVLQGDFRLVFVIKSFGPYLSAAILIGIIEGKNGLQRFRQRMRQRKAGWQWYLFILLGIPTLILLGIAVQPGALAGFLGVQPVLPLTYLVTYIAVMFGGGPLGEEPGWRGFALPRLQQRHGPLWGTLILSVCWTCWHLPDFLTSAQGGGPGTGLSAFLVNFPIFLALVTAIAILLTWIYNRTGGSIFLAILAHASVNTPQVVLVPLFPAVDTTSLNLAAMIGFGVSALVILILTRGQLGYQAEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X576</accession>
    <name>A0A0P6X576_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Endoribonuclease L-PSP</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_18505</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RutC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70049.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064527.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18505"/>
    <dbReference type="EnsemblBacteria" id="KPL70049">
        <property type="protein sequence ID" value="KPL70049"/>
        <property type="gene ID" value="ADN00_18505"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3009"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006056">
        <property type="entry name" value="RidA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019897">
        <property type="entry name" value="RidA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006175">
        <property type="entry name" value="YjgF/YER057c/UK114"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11803">
        <property type="entry name" value="PTHR11803"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01042">
        <property type="entry name" value="Ribonuc_L-PSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="SSF55298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00004">
        <property type="entry name" value="TIGR00004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01094">
        <property type="entry name" value="UPF0076"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70049.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="131" mass="13573" checksum="3FC61D11A03C0AA6" modified="2016-01-20" version="1">MTESIVKKVITTELAPKAIGPYSAGIEAGEFVFTSGQLGLDPASGDLVAGGVEAETQQALTNLKNVLEAGGSGLERVVKTTVFLRDIADFAKMNAVYATFFTSQPPARSAFQVGALPKGAAVEIEAVALKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X6J6</accession>
    <name>A0A0P6X6J6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_05375</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061947.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78683">
        <property type="protein sequence ID" value="KPL78683"/>
        <property type="gene ID" value="ADN00_05375"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="84"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="237"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="237"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="304"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="358" mass="40295" checksum="E3CA4A1B7854BD54" modified="2016-01-20" version="1">MERQKMHDELEQEIFERLTPLREVPPRQPHAVKAGRERFLAQAAKIRASLPVSKSADLRLSKQKRTFSTLFGLRKEPLPMIAQIGLAIVLALTVLAGGGGATVYASQTSQPDEFLYPVKIWSEDVRYDMATSETQQLQLAVEFANRRLEELQAQQLSQQPVDEAVVQRLRLHVDESLQLMTRLNLSEEDQLQIREQLRTQDRLMQQLSVAEGAPETALLLQVREMVREQLRLAGVETEQPVQTQQQNQQQQQNQQQMNQPETSPEAPQPGPGPQAEPLQEGNGPQNQNQSGEPAGVCPADQPDCDPVQQQQQTQQQDQSQQQNQDQQQEQPQQDQSQQQNQDNDSSSGSSDPGPKKGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X757</accession>
    <name>A0A0P6X757_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">ADN00_06185</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">In the N-terminal section; belongs to the CRISPR-associated nuclease Cas3-HD family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the central section; belongs to the CRISPR-associated helicase Cas3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06185"/>
    <dbReference type="EnsemblBacteria" id="KPL78884">
        <property type="protein sequence ID" value="KPL78884"/>
        <property type="gene ID" value="ADN00_06185"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1738"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3210.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035011">
        <property type="entry name" value="Cas3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006483">
        <property type="entry name" value="CRISPR-assoc_Cas3_HD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038257">
        <property type="entry name" value="CRISPR-assoc_Cas3_HD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006474">
        <property type="entry name" value="Helicase_Cas3_CRISPR-ass_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24031:SF539">
        <property type="entry name" value="PTHR24031:SF539"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01587">
        <property type="entry name" value="cas3_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01596">
        <property type="entry name" value="cas3_HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51643">
        <property type="entry name" value="HD_CAS3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HD Cas3-type" evidence="10">
        <location>
            <begin position="15"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="236"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL78884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="741" mass="84184" checksum="DBFDF273862803AC" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7D0</accession>
    <name>A0A0P6X7D0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_18530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FemABX family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064531.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18530"/>
    <dbReference type="EnsemblBacteria" id="KPL70053">
        <property type="protein sequence ID" value="KPL70053"/>
        <property type="gene ID" value="ADN00_18530"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016755">
        <property type="term" value="F:aminoacyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044038">
        <property type="term" value="P:cell wall macromolecule biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003447">
        <property type="entry name" value="FEMABX"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02388">
        <property type="entry name" value="FemAB"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51191">
        <property type="entry name" value="FEMABX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="331" mass="37891" checksum="EE988E813B93C821" modified="2016-01-20" version="1">MPELTFSEWDQFLTQYPQAHVLQTSAWGILKSKFSWQAVPVVSGLAGALVLFRRLPLGFSIAYIPKGPLGDNWNDLWPEIDRACRRRRAIFLQVEPDAFEPASASLLERLSGFKQVEKTIQPRQTIVVSLEGGEEDWLQRMKQKTRYNVRLAAKKEVVVRETNDVAQFHALMSTTGERDQFGVHSLAYYQAAYDLFSARGECALLQAEYAGKPLAAVMVFARGKRSWYFYGASSNEERNRMPAYLVQWEAMRWASARGCSEYDLWGIPDLPEETLEADFTQREDGLWSVYRFKRGFGGQIHRSTGAWDRVYMPLLYRAYQIAARARSGGEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7G2</accession>
    <name>A0A0P6X7G2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cell division protein Fic</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_13090</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000029">
        <property type="protein sequence ID" value="KPL75289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063471.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000029.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13090"/>
    <dbReference type="EnsemblBacteria" id="KPL75289">
        <property type="protein sequence ID" value="KPL75289"/>
        <property type="gene ID" value="ADN00_13090"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2895"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3290.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025758">
        <property type="entry name" value="Fic/DOC_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003812">
        <property type="entry name" value="Fido"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036597">
        <property type="entry name" value="Fido-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040198">
        <property type="entry name" value="Fido_containing"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026287">
        <property type="entry name" value="SoFic-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13504">
        <property type="entry name" value="PTHR13504"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02661">
        <property type="entry name" value="Fic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13784">
        <property type="entry name" value="Fic_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038925">
        <property type="entry name" value="AMP-prot_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140931">
        <property type="entry name" value="SSF140931"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51459">
        <property type="entry name" value="FIDO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-0132">Cell division</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fido" evidence="4">
        <location>
            <begin position="139"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="224"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="224"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="228"/>
            <end position="235"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="229"/>
            <end position="235"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="266"/>
            <end position="267"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="266"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR038925-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR640198-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51459"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL75289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="400" mass="45866" checksum="E47B9D88C53F2A3A" modified="2016-01-20" version="1">MNRRDFENSTAGKIIQVGQGNVAYWAFVPNPLPPDLAPEWELASLLSVADRAVSELAGLGRNLPNPDLFVSPFLRREAVLSSRIEGTQSDLTDLYLYEAGQVPLPGFESMISTEADVNEVRNYVLALEYGLERLRTLPVSLRLLCEIHERLLAGVRGEYATPGCFRTRQNWIGGRTINEAVYVPPPVDEMRAGLDAFEKYLYVDHPHPPLVRLAFLHYQFEALHTFVDGNGRIGRLLLALLLVNWKLLPQPLLYLSAYFERNRPDYYAHLLAISRRGAWREWVFFFLQGVKEQAHDTIWRIKQLQDLQTLWRGKLDNVRANATTLRLLEWLFVAPVISIPQAQKLLDVTYHTARRSVEKLIEMDILHQFGESDYDRRFIAKEILKTLNAEDGSLGRDNQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7R2</accession>
    <name>A0A0P6X7R2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_04095</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061688.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79067">
        <property type="protein sequence ID" value="KPL79067"/>
        <property type="gene ID" value="ADN00_04095"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.174"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="110"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="152"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="176"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="230"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="266"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="294"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="320"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="356"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="386"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="1"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="230"/>
            <end position="429"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL79067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="429" mass="45556" checksum="8E2510736FD6ACD4" modified="2016-01-20" version="1">MVLEQSKQNVDSKAWMKPFFFIFGGQVFSLLGSSVVQFSLIWWLTEKTGSAAVLTAAMLVGFLPEVVLGPFVGALVDRWNRRRVMILADSLVAVVTVVLIVLVWGGQLTMWPIFAALFLRSLGGVFHFTAMQASISLMVPENELSRVAGINQALRGVVNIVGPLLAAFLMGVLPFWGVLAVDVVTAFLAVLPLLIVAIPSPQSTGAVQSVKSVLADVREGLRYVRQWNGLFLLLVMATLLNFLFMPAFALMPLLVTEHFQGGALQLGWMESMFGAGIVIGGLALGAWGGFKRRIYTTMLGLMGMALGLGLVWGAPAQTLGMALAGMLLTGINMPIVNGPLFAIVQARVEPAMQGRVFSLMASISGAAVPLSMVIAGPTAELIGVRVWFLVAAAGCVLLGIGGALTPAIINLENEQQPRVQTEAAPNVVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X846</accession>
    <name>A0A0P6X846_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_04835</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SIMIBI class G3E GTPase family. ArgK/MeaB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061824.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04835"/>
    <dbReference type="EnsemblBacteria" id="KPL79176">
        <property type="protein sequence ID" value="KPL79176"/>
        <property type="gene ID" value="ADN00_04835"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.333"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005129">
        <property type="entry name" value="GTPase_ArgK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00750">
        <property type="entry name" value="lao"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009625"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="318" mass="33976" checksum="11D40A90166374D5" modified="2016-01-20" version="1">MNLVDGVLAGDRLALSRLLTAVENDTPAGRAGLDALFARTGRAYLVGITGSPGTGKSSLVNRLVKLFRNPPDGRPAWRVAVVAVDPTSPFTGGAVLGDRVRMRDCAGDPGVFIRSMASRGALGGLAVQTAAVTQVFDAAGYDVILIETVGAGQAEVDIASLAHTTLVVEAPGLGDDIQAIKAGILEIADVLVINKADLAGADNTRRALQTMLERAPAKPWPARLVSTVAVSGAGMEELFWAILDHYQFLKSSQEWQRRDAQRLRAGLDELIRAELVRRWREDTPAEVYESVLNRMAGRKLSPFEALDDLLTTRKQAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X8C1</accession>
    <name>A0A0P6X8C1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Flagellar biosynthesis protein FlhA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 8" type="primary">flhA</name>
        <name evidence="8" type="ORF">ADN00_17170</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Required for formation of the rod structure of the flagellar apparatus. Together with FliI and FliH, may constitute the export apparatus of flagellin.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the FHIPEP (flagella/HR/invasion proteins export pore) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71421.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064279.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17170"/>
    <dbReference type="EnsemblBacteria" id="KPL71421">
        <property type="protein sequence ID" value="KPL71421"/>
        <property type="gene ID" value="ADN00_17170"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.496"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009306">
        <property type="term" value="P:protein secretion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.540">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042194">
        <property type="entry name" value="FHIPEP_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042193">
        <property type="entry name" value="FHIPEP_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042196">
        <property type="entry name" value="FHIPEP_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006301">
        <property type="entry name" value="FlhA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001712">
        <property type="entry name" value="T3SS_FHIPEP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30161">
        <property type="entry name" value="PTHR30161"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00771">
        <property type="entry name" value="FHIPEP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005419">
        <property type="entry name" value="FlhA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00949">
        <property type="entry name" value="TYPE3IMAPROT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01398">
        <property type="entry name" value="FlhA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1005">Bacterial flagellum biogenesis</keyword>
    <keyword evidence="7" id="KW-1006">Bacterial flagellum protein export</keyword>
    <keyword evidence="3 7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0969">Cilium</keyword>
    <keyword evidence="8" id="KW-0282">Flagellum</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="46"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="77"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="118"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="204"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="237"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="283"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL71421.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="698" mass="75432" checksum="B4B9BE4E762F1D5D" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XA37</accession>
    <name>A0A0P6XA37_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_16105</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16105"/>
    <dbReference type="EnsemblBacteria" id="KPL72015">
        <property type="protein sequence ID" value="KPL72015"/>
        <property type="gene ID" value="ADN00_16105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004268">
        <property type="entry name" value="MurJ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03023">
        <property type="entry name" value="MurJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01806">
        <property type="entry name" value="VIRFACTRMVIN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0133">Cell shape</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="37"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="71"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="144"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="170"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="216"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="255"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="296"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="327"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="365"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="393"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="424"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="464"/>
            <end position="486"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL72015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="510" mass="54231" checksum="A4464101D81589F8" modified="2016-01-20" version="1">MATLLTRATNFLTQMVIAHHFGVNLDADAYFLVENGMLIAGSFLITSFSVAFIPIWTNSHIHEGPRAANRFHYGFVVLAMAASLGLSVVVGLVGFAFSSLLLQSGVDPLLQATGRLMLVASPAVALMGFTVGCTSILQANRHFLIPELGNISYNLVLLVAALFFAARLGMISLAWATVLAAVVRLLVQVPASRKISSFQTGKGDQSAGLGLVQKRVLPIFAAYAGTQVTLLLGNLMASNLPAGSVSALVYASRVMLLPVGILVLPLQTTILPTLSQQVAHKDLRLLGKTMLDTFRMLVLVGIPISVGIVFLRLPLVQLLYQRGAFDAAASALTADLLAFFALGLPAVALLMLINSVYCAMGDMQALVLVNGFHWAATALLGAVLVRVAGASGAAMSISISTTLACVLGLARLKKSIPTFKLNGLVEVVAKSAIASGVMFLLLTGANLLMTQGLKLQLTWQWTEAVLQIVLAVLLGGSSFTIAAWLLKIDEFQVWRERMSFSKSSLRIRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAJ5</accession>
    <name>A0A0P6XAJ5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_04570</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79136.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061775.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04570"/>
    <dbReference type="EnsemblBacteria" id="KPL79136">
        <property type="protein sequence ID" value="KPL79136"/>
        <property type="gene ID" value="ADN00_04570"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.275"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79136.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="209" mass="23075" checksum="AF5B742324AC635A" modified="2016-01-20" version="1">MPTILLIRHGENDMLKKGLAGRLPAIHLNEAGQRQAQEIASALAAAPIKAIYSSPMERALETAQPLAQAKGLEVQVLAGLNEVDFGDWQGASYTDLQKEALWKQVQEDAQAVRFPGGETLVEVQQRAVAEIERLAAESGEKDVVACFTHGDVVRLLTAHYLNMALNDFQRLLTFTASITTLHFDGVLPRVLNYNQVVNFNWPEEEEKQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAT0</accession>
    <name>A0A0P6XAT0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PfkB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09555</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77352.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062762.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09555"/>
    <dbReference type="EnsemblBacteria" id="KPL77352">
        <property type="protein sequence ID" value="KPL77352"/>
        <property type="gene ID" value="ADN00_09555"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PfkB" evidence="1">
        <location>
            <begin position="1"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77352.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="311" mass="33929" checksum="D72A660DB3BC5DE8" modified="2016-01-20" version="1">MTKALVLGEICIDVILNNPASVPVLGKNVWAESIQMRLGGSATYVSQGLQVLGIPTTVNSVVGEDPLIEVYLNQLQYLGIDISHVHRQPSAATSVCIGVVDKEKKSFIGCSPFLKYPDHLLEINPEEFDLVYFGGYLLYPEIWDGKLSNLLQKVRPDAHTILDTQMLPIPVDLYRDRAITKSLLEQVEVLLVDRKEAIALTKRQNPEEAARILADYGPKIITVKLGGQGCLVLTQGEILKSKSLKVDARDLIGAGDFFGAAFSYGVLMGWPLQKTADFANGFAALCAARKESNALPELSLVLKHIFPSAIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XB35</accession>
    <name>A0A0P6XB35_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Transglycosylase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_10155</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPF0410 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062889.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10155"/>
    <dbReference type="EnsemblBacteria" id="KPL76944">
        <property type="protein sequence ID" value="KPL76944"/>
        <property type="gene ID" value="ADN00_10155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007341">
        <property type="entry name" value="Transgly_assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33884">
        <property type="entry name" value="PTHR33884"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04226">
        <property type="entry name" value="Transgly_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="31"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="56"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL76944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="83" mass="8348" checksum="22975BDD6DD66775" modified="2016-01-20" version="1">MDIQSLLMFLLIGLVAGWLAGKIMKGGGFGLVGNIIVGAIGALLGGWLFGLLGISAGGLIGSLVTALVGAIVLLYLVRLIKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XB52</accession>
    <name>A0A0P6XB52_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_02935</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000013">
        <property type="protein sequence ID" value="KPL79411.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061460.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000013.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02935"/>
    <dbReference type="EnsemblBacteria" id="KPL79411">
        <property type="protein sequence ID" value="KPL79411"/>
        <property type="gene ID" value="ADN00_02935"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2222"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018687">
        <property type="entry name" value="DUF2177_membr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09945">
        <property type="entry name" value="DUF2177"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="111"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79411.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="132" mass="14891" checksum="B9358CDF58C78560" modified="2016-01-20" version="1">MLILLRNFLITLVSFFAVDILWLGLVARTFYRNQIGFLLAPRTNWLAAGLFYLFYLVGLSYFVLYPALAQGSWQAVLLNGCIFGFMAYMTYDLTNLATLKDWPALLAVVDIAWGTVLTGVTALLSYWVIGLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBH9</accession>
    <name>A0A0P6XBH9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">2-hydroxyacid dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_16390</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72055.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064120.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16390"/>
    <dbReference type="EnsemblBacteria" id="KPL72055">
        <property type="protein sequence ID" value="KPL72055"/>
        <property type="gene ID" value="ADN00_16390"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001694">
        <property type="entry name" value="NADH_UbQ_OxRdtase_su1/FPO"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00146">
        <property type="entry name" value="NADHdh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="71"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="105"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="139"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="166"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="252"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="284"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL72055.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="303" mass="32519" checksum="B3724B50DED18E97" modified="2016-01-20" version="1">MIDGWLRVLINLLIWPGLLSGTVLGWMLLWFGRKITARLQGRQGPPFFQPFFDFWKLIGKKTVIPAGVSPFVFYTLPVISLLSVTAALALLPVPGGSAISFEGDLVLLIYLLEMPALMDILAGYVTRSVYAQVGSAREAVLILAYNLPFLSALIALGLQLKTFQLAAFAAAPVSLVTILTAAALLLALLAQLKINPFSIPNAEQEIVAGIHVEYNGLPLALFELTHALEAATLVGLIGSLFLGAVSPVWLKVVVLLLAAVVVVFLANGIAASTARLKVQHAFRFYWSWGILAAVLVFCASLAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XCZ6</accession>
    <name>A0A0P6XCZ6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Lar_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01695</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061228.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01695"/>
    <dbReference type="EnsemblBacteria" id="KPL80581">
        <property type="protein sequence ID" value="KPL80581"/>
        <property type="gene ID" value="ADN00_01695"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1101"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050043">
        <property type="term" value="F:lactate racemase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.226.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043166">
        <property type="entry name" value="LarA-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018657">
        <property type="entry name" value="LarA-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09861">
        <property type="entry name" value="Lar_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lar_N" evidence="1">
        <location>
            <begin position="10"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF09861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="437" mass="47567" checksum="9C89CA147DFF2569" modified="2016-01-20" version="1">MSQKISFPWGSKSIDLELPETWTLMGNMEPASRVGIDDPHAETEAALRAPIGSPRLAELAAHGMKIALVIDDDSRPTPVKDILPAVARELQESGAALSQVTVVPALGVHRPMTEEEIARRLGQGWLEQMNWVQHDCDDPEKLVYLGDTSRGTPVWFNKTVAEADLIISIGCIEPHIIASFGGGYKNLLPGVAARQSIAHNHAINCQPETFNMVGQPIENNPMRLDLEEAGGMLKAPVFVINAVLNSAMQVVRIVAGDPIQAHREGARTSAEIFGCPLPRLADVVITASRPMDQDLRQGVKALANTIRALKPGGVMITLIRAEEGVGVFGLANRKLPVGKTMLRLLAPLLLPRIGKLNLKGMGEEDRFFLYFALQAMLHGKLLLYAPTIPAEIHERMPFVEFVGSPQEALQMAMKKYPAKADVVVFPYGGSSYPILPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XD38</accession>
    <name>A0A0P6XD38_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Glycerol-3-phosphate acyltransferase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Acyl-PO4 G3P acyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Acyl-phosphate--glycerol-3-phosphate acyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">G3P acyltransferase</fullName>
            <shortName evidence="10">GPAT</shortName>
            <ecNumber evidence="10">2.3.1.275</ecNumber>
        </alternativeName>
        <alternativeName>
            <fullName evidence="10">Lysophosphatidic acid synthase</fullName>
            <shortName evidence="10">LPA synthase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="primary">plsY</name>
        <name evidence="11" type="ORF">ADN00_01065</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10">Catalyzes the transfer of an acyl group from acyl-phosphate (acyl-PO(4)) to glycerol-3-phosphate (G3P) to form lysophosphatidic acid (LPA). This enzyme utilizes acyl-phosphate as fatty acyl donor, but not acyl-CoA or acyl-ACP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>an acyl phosphate + sn-glycerol 3-phosphate = a 1-acyl-sn-glycero-3-phosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:34075"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57597"/>
            <dbReference type="ChEBI" id="CHEBI:57970"/>
            <dbReference type="ChEBI" id="CHEBI:59918"/>
            <dbReference type="EC" id="2.3.1.275"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="10">Lipid metabolism; phospholipid metabolism.</text>
    </comment>
    <comment type="subunit">
        <text evidence="10">Probably interacts with PlsX.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="10">Belongs to the PlsY family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.275" evidence="10"/>
    <dbReference type="EMBL" id="LGCL01000003">
        <property type="protein sequence ID" value="KPL80813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061113.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01065"/>
    <dbReference type="EnsemblBacteria" id="KPL80813">
        <property type="protein sequence ID" value="KPL80813"/>
        <property type="gene ID" value="ADN00_01065"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00085"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043772">
        <property type="term" value="F:acyl-phosphate glycerol-3-phosphate acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01043">
        <property type="entry name" value="PlsY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003811">
        <property type="entry name" value="G3P_acylTferase_PlsY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30309">
        <property type="entry name" value="PTHR30309"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02660">
        <property type="entry name" value="G3P_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01207">
        <property type="entry name" value="G3P_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2 10" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6 10" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8 10" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="9 10" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="48"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="84"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="140"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="172"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL80813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="218" mass="22767" checksum="9C50340BD26FB7AB" modified="2016-01-20" version="1">MALILVGLIAAYLIGSIPNGLLIVWLFSGKDVRKIESGRTGGTNAMRAAGFAAGLLTTLLDVLKGAGAVWLARWLSPGNFWLEAAAAVLAVIGHNYSIYLLERNEDGRLRLRGGAGGTCALGGAIGLWPLSLVIMTPIAIAAFVLVGYASVATISIGLGATVVFLVRALMGVGPWAHVAYGAASLALILWALRPNLKRIANGTERPVGLRAARMKKQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDK6</accession>
    <name>A0A0P6XDK6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_08015</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062468.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08015"/>
    <dbReference type="EnsemblBacteria" id="KPL77822">
        <property type="protein sequence ID" value="KPL77822"/>
        <property type="gene ID" value="ADN00_08015"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.603"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003797">
        <property type="entry name" value="DegV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043168">
        <property type="entry name" value="DegV_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02645">
        <property type="entry name" value="DegV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00762">
        <property type="entry name" value="DegV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51482">
        <property type="entry name" value="DEGV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="280" mass="30784" checksum="C9E521B979D6B96A" modified="2016-01-20" version="1">MLRIVGDTTSVLPPKISAEHGITIMPQIINFGSKSYRDDTELDTATFLRLLRSSRDLPKTAAPPPSLYTPVYQQALNAGDQVLVLCPSADTSGTFRSAQLAAQEFNSPDIHIMDTRLIAGGLGRLLILASQWSKQGLDVETIKTRLESWRKRERIYFVVDTLEYLAKGGRIGNAQALLGGLLQLKPILTMENGVNTPVESQRTKKRAISRFKELVLEECPPTPDSYLCVIHSDAEEVARQYAAEFSQKLGIPDVPVYEQCASIVVHVGPGVIAASFFCPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDL4</accession>
    <name>A0A0P6XDL4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NAD(P)-bd_dom domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_08065</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062477.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08065"/>
    <dbReference type="EnsemblBacteria" id="KPL77831">
        <property type="protein sequence ID" value="KPL77831"/>
        <property type="gene ID" value="ADN00_08065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13460">
        <property type="entry name" value="NAD_binding_10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="6"/>
            <end position="151"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="296" mass="32383" checksum="921AF20CE3932728" modified="2016-01-20" version="1">MILVTGGTGFVGRSLVRHLVASGRPVRILLRPSAESPNLPRGLSVEVAVCGLSDERGLRAAMKDVDTVFHLATAEHKGGKADLNGVDVEGTEHLARAAQQAGVERLFYLSHLGADRLSAYPVFRAKALAESTIQQSGVPYTIFRSGLLVGEGDHFTTAMLRLIKASPFFLFVPEDGETVIQPLWVEDLVVCLELALSDESLVGQTLSVGGSEYLSFREVMEKILGKIGKRRGFISASPAYLRLLGLFWDQIAPKQSISYYWLDYLAADRTCAVDTLPRLFGLMPARFTQLLGYLQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDP9</accession>
    <name>A0A0P6XDP9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SHSP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_00150</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the small heat shock protein (HSP20) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060932.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00150"/>
    <dbReference type="EnsemblBacteria" id="KPL81001">
        <property type="protein sequence ID" value="KPL81001"/>
        <property type="gene ID" value="ADN00_00150"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002068">
        <property type="entry name" value="A-crystallin/Hsp20_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008978">
        <property type="entry name" value="HSP20-like_chaperone"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00011">
        <property type="entry name" value="HSP20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49764">
        <property type="entry name" value="SSF49764"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01031">
        <property type="entry name" value="SHSP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SHSP" evidence="3">
        <location>
            <begin position="34"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00285"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003616"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS01031"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL81001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="141" mass="16460" checksum="9B2A3F5F3C875917" modified="2016-01-20" version="1">MILIKTRITSKPSPETTITESFYFSSSANRWEQNLPTTWTPPVDIFEIDDKYIIRMEIAGMNEEDFTIILEKNLLSIRGIRKDPELKRAFHQMEIHYGEFHFEIAFSALIAYEEVTATYENGFLDIALPKAQPRQINIQND</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDS2</accession>
    <name>A0A0P6XDS2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_08350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062528.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08350"/>
    <dbReference type="EnsemblBacteria" id="KPL77877">
        <property type="protein sequence ID" value="KPL77877"/>
        <property type="gene ID" value="ADN00_08350"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.672"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018746">
        <property type="entry name" value="DUF2298"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10060">
        <property type="entry name" value="DUF2298"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03662">
        <property type="entry name" value="Chlor_Arch_YYY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="24"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="91"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="128"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="177"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="240"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="270"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="339"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="395"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="435"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="953"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="994"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1018"/>
            <end position="1037"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1049"/>
            <end position="1069"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1115"/>
            <end position="1133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1140"/>
            <end position="1161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1181"/>
            <end position="1200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1275"/>
            <end position="1293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1330"/>
            <end position="1349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1361"/>
            <end position="1386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1407"/>
            <end position="1427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1447"/>
            <end position="1468"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1473"/>
            <end position="1492"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1498"/>
            <end position="1519"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1531"/>
            <end position="1552"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="1564"/>
            <end position="1586"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="1756" mass="197855" checksum="95D5AF1498FABCC5" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDX8</accession>
    <name>A0A0P6XDX8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">4Fe-4S ferredoxin-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_08200</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08200"/>
    <dbReference type="EnsemblBacteria" id="KPL77913">
        <property type="protein sequence ID" value="KPL77913"/>
        <property type="gene ID" value="ADN00_08200"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.641"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008616">
        <property type="term" value="P:queuosine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004155">
        <property type="entry name" value="PBS_lyase_HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004453">
        <property type="entry name" value="QueG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013542">
        <property type="entry name" value="QueG_DUF1730"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30002">
        <property type="entry name" value="PTHR30002"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08331">
        <property type="entry name" value="DUF1730"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00567">
        <property type="entry name" value="EZ_HEAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="SSF48371"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00276">
        <property type="entry name" value="TIGR00276"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-0671">Queuosine biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="7">
        <location>
            <begin position="182"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL77913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="380" mass="42129" checksum="F90034F1F23BB456" modified="2016-01-20" version="1">MTMDAKEMLKAEARRLGFSHLGITALDPTPHASAYLGWLEQGWHASMAYLSAPRAVEHRLNPQQVFPPARSLIVVTAAYPPPSTPNQAESQPGYGLVAAYARGVDYHTLLPPQLRRLVQWIQNEIDPRAQAAVYTDTGPILERDYASRAGLGWIGKNTCLINPQAGSYLLLAEIFLSTLLEPDEPFEKDLCGTCRRCIEACPTGCISEARLLDSRRCISYLTIENKGEIPIELRPLIGSHVFGCDICQQVCPWNQKIKTAPKTPLFQSDPALSELELAATLRLSPQEFNRRYRQTPLQRAKRRGLLRNAAVVAGNQRAEAALPVLINLLEEEFEPLVRAHAAWALGQFNNRAGRVALEKALKTESDPTILAEIRSALDSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XF22</accession>
    <name>A0A0P6XF22_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_06105</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062081.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78797">
        <property type="protein sequence ID" value="KPL78797"/>
        <property type="gene ID" value="ADN00_06105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="212" mass="23844" checksum="45D16085CB710019" modified="2016-01-20" version="1">MDASFTQQWTSEMRRWTESLFPNCELSFPVPNLGNPYSGTLSLTAFWYRVSPGPGPQLLYIGVPDGRITALYPEPQTIRVGFAPWVTIDRAALLQKIAGCQIQVDPFFDDRFFRSLPESGRLGIMASQPKSQNPSRALSQLFHLYDQCLSQYLGGAPAHPKTRPAFYQSFVQLTPPGLFLYYRRINMAFWDWVEAGIAPTSSAKQEEVVGLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XF99</accession>
    <name>A0A0P6XF99_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_07690</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07690"/>
    <dbReference type="EnsemblBacteria" id="KPL78325">
        <property type="protein sequence ID" value="KPL78325"/>
        <property type="gene ID" value="ADN00_07690"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50894">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HPt" evidence="6">
        <location>
            <begin position="15"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="132"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="258"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="5">
        <location>
            <begin position="414"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="65"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="181"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL78325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="554" mass="61950" checksum="3E4A15E1EB22A12B" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XFC9</accession>
    <name>A0A0P6XFC9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_07600</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BMP lipoprotein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07600"/>
    <dbReference type="EnsemblBacteria" id="KPL78361">
        <property type="protein sequence ID" value="KPL78361"/>
        <property type="gene ID" value="ADN00_07600"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3349"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003760">
        <property type="entry name" value="PnrA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02608">
        <property type="entry name" value="Bmp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="domain" description="Bmp" evidence="3">
        <location>
            <begin position="20"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL78361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="330" mass="34437" checksum="0C53B9A04560C67C" modified="2016-01-20" version="1">MAEQAAGSAEALPSGAGMKVCQVTDAGGIDDKSFNATAYKGVVEAADKMGFEGKYLESQQQTDYEKNINAFLEEECDLIVTVGFLLGDATAAAATANPDQKFAIVDFAYDPAFENVLGLTFDTDQAGFLAGYLAAGMTKTGKVGTFGGMQIPTVTIFMDGFAEGVAYYNQEKGTEVEVLGWDPETQTGLFTGNFESTDDGRALGETLMDEGADIIMPVAGPVGLGTAAAIMERGNAYMIGVDYDWYVSAPEYASIMLTSVEKGMDVAVFEAAKAVAAGNFAGGAYLGTLENGGVGLAEYHDLDSMVPADLKAEVEALKAMIIAGDVKVGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XFK1</accession>
    <name>A0A0P6XFK1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ACP_syn_III_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_06850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000018">
        <property type="protein sequence ID" value="KPL78435.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062237.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000018.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06850"/>
    <dbReference type="EnsemblBacteria" id="KPL78435">
        <property type="protein sequence ID" value="KPL78435"/>
        <property type="gene ID" value="ADN00_06850"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2286"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01409">
        <property type="entry name" value="UPF0219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013747">
        <property type="entry name" value="ACP_syn_III_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004656">
        <property type="entry name" value="FabH-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08541">
        <property type="entry name" value="ACP_syn_III_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="SSF53901"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00748">
        <property type="entry name" value="HMG_CoA_syn_Arc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ACP_syn_III_C" evidence="1">
        <location>
            <begin position="236"/>
            <end position="322"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF08541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78435.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="363" mass="38531" checksum="D198A5E4EA42A3B4" modified="2016-01-20" version="1">METPETQPQPSLALKPNRAVGITGYGAYVPQYRLPAAEVARIWSGSDEDGGGPVIEKSVPGMDEDVISMSIEAARNALARAEICACELRAVWVGSESHPYAVKPSGTIVAEAIGAGNHIQAGDWEFACKAGSEAMIAAIGLVGSGMANYAMAIGMDTAQGRPGDQLEYTAAAGGAAYIIGPAENALATIEASYSYVSDTPDFWRRPYQKYPEHGQRFTGEPAYFKHITSAAKTLMKELGAQPGDFKYAVFHQPNTKFPTRVAGLLGFSKEQIQTGLLSPRIGNTYAGAALIGLTAVLDVAQPGDRILMTSFGSGAGSDALVLTATEALLARREKALSTEQYIARRVAIDYAQYARMRGILTLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XFK7</accession>
    <name>A0A0P6XFK7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Ribokinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_03500</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78971.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061579.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03500"/>
    <dbReference type="EnsemblBacteria" id="KPL78971">
        <property type="protein sequence ID" value="KPL78971"/>
        <property type="gene ID" value="ADN00_03500"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.51"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00583">
        <property type="entry name" value="PFKB_KINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="3">
        <location>
            <begin position="34"/>
            <end position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL78971.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="321" mass="35521" checksum="6A868E4025AD257D" modified="2016-01-20" version="1">MSVVCTGSIAFDYLMSFPGHFREHILSDHLDTISLSFLVDEMVRQPGGTATNIAYNLALLGEHPRLMATAGVDFEEYRRWLESKAVDTSLVKIIPDKFTASFFVNTDLDNNQIATFYAGAMAHACELSLHDLKAGLPDLLIISANDPGAMRCYARECKELGVPYLYDPSQQIVRICADELREGVEGAYALFVNEYEFELLQKHTGLKPEEILSKVGFMVVTLGEDGADIYAEGKKYHVPVVPPTQIAEPTGVGDAFRGGFVRGLRLGLGWETCGKMGALSATYCLEQKGTQNHTYTIAEYIARYRQHFDDQGALDVLLKNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XG89</accession>
    <name>A0A0P6XG89_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HTH deoR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_05365</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78681.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05365"/>
    <dbReference type="EnsemblBacteria" id="KPL78681">
        <property type="protein sequence ID" value="KPL78681"/>
        <property type="gene ID" value="ADN00_05365"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014036">
        <property type="entry name" value="DeoR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001034">
        <property type="entry name" value="DeoR_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018356">
        <property type="entry name" value="Tscrpt_reg_HTH_DeoR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00455">
        <property type="entry name" value="DeoRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08220">
        <property type="entry name" value="HTH_DeoR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00037">
        <property type="entry name" value="HTHLACR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00420">
        <property type="entry name" value="HTH_DEOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00894">
        <property type="entry name" value="HTH_DEOR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51000">
        <property type="entry name" value="HTH_DEOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH deoR-type" evidence="4">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL78681.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="251" mass="27000" checksum="9E39C19207501A6F" modified="2016-01-20" version="1">MEERRQNILRLLDLQGKVSVTDLSTVFSVSEVTIRADLQALADSGLLIRTHGGALKADPALVDITLTSRRERKASEKSRIGQAAAQLVQDGDSIFLDSSSTALAIAPHLKNRRNLTVLTNCIAVAQELMDAPEITVVMTGGRLRRDTASLVGGENLDVLARYNIQKGFFGAHGIDFVEGLTDVSADEAEVKRLLVAKCRMVIAVLDASKWGRVGLSSFATFSSVRVIVTDTNAPAELVARARMEGVEVVSV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGB4</accession>
    <name>A0A0P6XGB4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Fucose isomerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_05655</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061997.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05655"/>
    <dbReference type="EnsemblBacteria" id="KPL78727">
        <property type="protein sequence ID" value="KPL78727"/>
        <property type="gene ID" value="ADN00_05655"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1608"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008736">
        <property type="term" value="F:L-fucose isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006004">
        <property type="term" value="P:fucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015888">
        <property type="entry name" value="Fuc_isomerase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009015">
        <property type="entry name" value="Fucose_isomerase_N/cen_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02952">
        <property type="entry name" value="Fucose_iso_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53743">
        <property type="entry name" value="SSF53743"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fucose_iso_C" evidence="2">
        <location>
            <begin position="339"/>
            <end position="465"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="468" mass="51691" checksum="0A625FEAD8A2981B" modified="2016-01-20" version="1">MEKITLGVIFGNRDFFPSHLVSTARKDIAAVFEELNLDAVILDEKETVFGSVENYQHSKACAELFAANRDRIDGILVVLPNFGDEKGIADAIKLSGLRVPIMVQAYPDDTELFDVANRRDAYCGKISVCNNLRQYGYAYTLTDLHTVHPSEDSFKKDLYRFSRVCKVVRKLENVRLGSVGARPQAFNTVRYSEKLLQEAGITVITADLSEIMGEAGRMKDSDAPVKAKLDDIRAYLPANGVPSDAVVRMAKFGAALDSWMKEFDVQATALQCWNSVQKNFGINVCTLMSMMSESLMPSACEVDVTGVLSMYSLQLATGKPAALVDWNNNYKKDPDKCVLFHCGNWAKSFYEEARMEYANILATTLGQENTYGAINGNVAAGPMSFARVSTDDSYGIIRAYVGDGAFTDDPLDTFGSRAVVQIPGLQDLMKYVCKNGFEHHAAITPALSSEILAEAFETYKGWDVYKHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XH00</accession>
    <name>A0A0P6XH00_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_02735</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000013">
        <property type="protein sequence ID" value="KPL79373.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061428.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000013.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02735"/>
    <dbReference type="EnsemblBacteria" id="KPL79373">
        <property type="protein sequence ID" value="KPL79373"/>
        <property type="gene ID" value="ADN00_02735"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79373.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="209" mass="23367" checksum="BB753778AA3B39BA" modified="2016-01-20" version="1">MNYPLCIFDFDGTLADSFPWLNGVINQVMQAHHLKPLSPEEIDLLRAGDGQRVIQARSLPFWRIPIIARDMRRRMRADARQIHPFPGVASTLQSLADRGARLAIVSSNARENVESVLGAQTCALIQRFECSVPIHGKARVLRRVSRRMNLPPSQAIYIGDELRDLQAARQAGMPFGAVSWGYNTLAALQAGQPEEVFTRFEDILTLFAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XHB4</accession>
    <name>A0A0P6XHB4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA small subunit methyltransferase E</fullName>
            <ecNumber evidence="6">2.1.1.193</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_04940</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>S-adenosyl-L-methionine + uridine(1498) in 16S rRNA = H(+) + N(3)-methyluridine(1498) in 16S rRNA + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42920"/>
            <dbReference type="Rhea" id="RHEA-COMP:10283"/>
            <dbReference type="Rhea" id="RHEA-COMP:10284"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74502"/>
            <dbReference type="EC" id="2.1.1.193"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 6">Belongs to the RNA methyltransferase RsmE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.193" evidence="6"/>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79193.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061842.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04940"/>
    <dbReference type="EnsemblBacteria" id="KPL79193">
        <property type="protein sequence ID" value="KPL79193"/>
        <property type="gene ID" value="ADN00_04940"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.355"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1280.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029028">
        <property type="entry name" value="Alpha/beta_knot_MTases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006700">
        <property type="entry name" value="rRNA_ssu_MeTrfase-E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029026">
        <property type="entry name" value="tRNA_m1G_MTases_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30027">
        <property type="entry name" value="PTHR30027"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04452">
        <property type="entry name" value="Methyltrans_RNA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015601">
        <property type="entry name" value="MTase_slr0722"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75217">
        <property type="entry name" value="SSF75217"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00046">
        <property type="entry name" value="TIGR00046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="111"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR015601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL79193.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="250" mass="27489" checksum="E21CEBDA1DEB9B44" modified="2016-01-20" version="1">MHRFFLPPQNFSAGTVFFTEETAFQMHRVLRLKPGQLVVALDGQGREAEVRLESLSSREASGSIVRETAARGEPRFALTLLLALTQREKFEWMLQKCTELGAVHFVPVICARSLQQDGKDAEKKLERWRRIVKEAAEQSRRGRVPGVSQPMLFSALAASEGPVPSLKLIAWEAEEARSLADVLRASGDGYARGRVLIGPEGGFEPAEVTAAAACGFQPFSLGRRILRMETAAITCTALLMYALGEMEPGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XHH2</accession>
    <name>A0A0P6XHH2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_13775</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063603.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000032.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13775"/>
    <dbReference type="EnsemblBacteria" id="KPL74359">
        <property type="protein sequence ID" value="KPL74359"/>
        <property type="gene ID" value="ADN00_13775"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008289">
        <property type="term" value="F:lipid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003797">
        <property type="entry name" value="DegV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043168">
        <property type="entry name" value="DegV_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02645">
        <property type="entry name" value="DegV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00762">
        <property type="entry name" value="DegV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51482">
        <property type="entry name" value="DEGV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL74359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="283" mass="31039" checksum="B2FAB7DC922C7089" modified="2016-01-20" version="1">MNSICIVTDDSAQFLTPQYPGSSFTFILPNQVHLEGKSQKISSARDLPKTAGEDFHPRLEGPSVESYRQFFQQLGQSFNVIVCILASSHLTNSVDNAREAASGFHGAPVIQIIDSGSFAIGLGLIVQSAAKAIQQGANGIEVERIARDLIQRSYAVICAPGLSYLASNHFLDHAQASVGEMLSIFPIYSLEDGNLVPVDKVRNHRHAIIYYQEFIEEFDDLENIAFLQSAPPNPQDTRLLREFVHENFGGAVFSEHSINLPCASLFGPRTTSLFLVESQQASI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XIT8</accession>
    <name>A0A0P6XIT8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_02210</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Lgt family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000009">
        <property type="protein sequence ID" value="KPL79797.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061329.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000009.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02210"/>
    <dbReference type="EnsemblBacteria" id="KPL79797">
        <property type="protein sequence ID" value="KPL79797"/>
        <property type="gene ID" value="ADN00_02210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008961">
        <property type="term" value="F:phosphatidylglycerol-prolipoprotein diacylglyceryl transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042158">
        <property type="term" value="P:lipoprotein biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001640">
        <property type="entry name" value="Lgt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30589">
        <property type="entry name" value="PTHR30589"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01790">
        <property type="entry name" value="LGT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="84"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="114"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="161"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="187"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="211"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79797.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="239" mass="25495" checksum="BE6A05CBEF7BC942" modified="2016-01-20" version="1">MLPILQIGPLSLPTVPLLWILGFWIFSEAAESGARETGLDSKQVSRVVTLAVVLGLVGARLAYVLQYPNLFAENPLSVVSPRPYLLSLEGGLLFGGFGLLVLAQRKEMPIQRLLDALSPGFAFWLALVGLAWQAEGVFPVRGALLASGGSLPGGLTHPANLYWAVGFAVVGFLGRHALRRKSPAGEAFLGTVLLGGWFAIVHAFFRADMGTGRSIEALVGCALLILAGWQINHRARKTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XJE8</accession>
    <name>A0A0P6XJE8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PadR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_16885</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064225.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL71380">
        <property type="protein sequence ID" value="KPL71380"/>
        <property type="gene ID" value="ADN00_16885"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018309">
        <property type="entry name" value="Tscrpt_reg_PadR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005149">
        <property type="entry name" value="Tscrpt_reg_PadR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03551">
        <property type="entry name" value="PadR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10400">
        <property type="entry name" value="Vir_act_alpha_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PadR" evidence="1">
        <location>
            <begin position="7"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="Vir_act_alpha_C" evidence="2">
        <location>
            <begin position="92"/>
            <end position="170"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10400"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL71380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="180" mass="21129" checksum="CD20DE0FB2D8B238" modified="2016-01-20" version="1">MSVKHAILGLLSWQPLSGYDLKKIFSDSTAFYWSGNNNQVYRTLLELYDEGLVSREIIQQENLPAKKIYTISEKGRQELRQWITVNPELPVLRNSFLIQLAWADQLTPPELENLLASYEEEIHTQWLIHNQSSPQLSPEQARSPREALLWSAIHQNQLRFYQTEWDWVKHLRVSLAEIQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKM9</accession>
    <name>A0A0P6XKM9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_01530</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80552.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80552">
        <property type="protein sequence ID" value="KPL80552"/>
        <property type="gene ID" value="ADN00_01530"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL80552.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="164" mass="18317" checksum="C13707F5BE5E0A00" modified="2016-01-20" version="1">MRPARGSFADPLLVISCLRHGKKAVSRPALASAKPAFFYPAAVDNYVKIVDNLTAHVETLPRSAGNIRIYADIAIFYPPYLGETWENSDSPRACHLWKNPPKLWITSANLVDNHLRILWKTDLSMAKPALARGKHSARGGKPSTTRGKNTASLWINWRLSVDNW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XLT5</accession>
    <name>A0A0P6XLT5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">30S ribosomal protein S15</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">rpsO</name>
        <name evidence="7" type="ORF">ADN00_12405</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Forms an intersubunit bridge (bridge B4) with the 23S rRNA of the 50S subunit in the ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="3 6">One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it helps nucleate assembly of the platform of the 30S subunit by binding and bridging several RNA helices of the 16S rRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Part of the 30S ribosomal subunit. Forms a bridge to the 50S subunit in the 70S ribosome, contacting the 23S rRNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the universal ribosomal protein uS15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063331.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12405"/>
    <dbReference type="EnsemblBacteria" id="KPL76133">
        <property type="protein sequence ID" value="KPL76133"/>
        <property type="gene ID" value="ADN00_12405"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3962"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00353">
        <property type="entry name" value="Ribosomal_S15p_S13e"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01343_B">
        <property type="entry name" value="Ribosomal_S15_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000589">
        <property type="entry name" value="Ribosomal_S15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005290">
        <property type="entry name" value="Ribosomal_S15_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009068">
        <property type="entry name" value="S15_NS1_RNA-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23321">
        <property type="entry name" value="PTHR23321"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00312">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01387">
        <property type="entry name" value="Ribosomal_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47060">
        <property type="entry name" value="SSF47060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00952">
        <property type="entry name" value="S15_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00362">
        <property type="entry name" value="RIBOSOMAL_S15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="1 3 4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 6" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01343"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL76133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="90" mass="10677" checksum="B2DF0F0AFCCDCA96" modified="2016-01-20" version="1">MTFTKEQKAEVIEKYRRDETDTGSPEVQVAILTYRVNQLTDHLRTHKHDESSRRGLLKLVGQRRRLLSYLKSKDYNRYVALADSLNIRKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XMM0</accession>
    <name>A0A0P6XMM0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_08595</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000022">
        <property type="protein sequence ID" value="KPL77647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062585.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000022.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08595"/>
    <dbReference type="EnsemblBacteria" id="KPL77647">
        <property type="protein sequence ID" value="KPL77647"/>
        <property type="gene ID" value="ADN00_08595"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1430"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL77647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="194" mass="21478" checksum="AE02DDF43968EDB7" modified="2016-01-20" version="1">MTEIWLVRHAQTDWNMERRFQGQSDIPLNETGRQQARQLAGSLAAAGKAFQAVYSSPLSRAMQTASAVAERLNLPLQAEPRIREANLGEWEGMLAEEIPLRYPDLVEARRRDPFNVPPPGEQAENVASIAGRASQAMDAIARHHNGQPVLVVTHGLVIATLVCLNRQIAFEEVFQQIPHNAQPVVLHWKVAGNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XNQ0</accession>
    <name>A0A0P6XNQ0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_09895</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062838.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09895"/>
    <dbReference type="EnsemblBacteria" id="KPL76901">
        <property type="protein sequence ID" value="KPL76901"/>
        <property type="gene ID" value="ADN00_09895"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2439"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008727">
        <property type="entry name" value="PAAR_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05488">
        <property type="entry name" value="PAAR_motif"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="96" mass="9404" checksum="E06DBB56CD1794A4" modified="2016-01-20" version="1">MPPAARMGDTTAHGGVITVGFPTVLIGGQPAARVGDLHTCPMVNGVVPHVGGPIMPPGSPTVLIGGLPAARLGDMATCVGPPDSIVMGCMTVIIGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XP88</accession>
    <name>A0A0P6XP88_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">UPF0173 metal-dependent hydrolase ADN00_06840</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_06840</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0173 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000018">
        <property type="protein sequence ID" value="KPL78433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062235.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000018.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06840"/>
    <dbReference type="EnsemblBacteria" id="KPL78433">
        <property type="protein sequence ID" value="KPL78433"/>
        <property type="gene ID" value="ADN00_06840"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2283"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00457">
        <property type="entry name" value="UPF0173"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022877">
        <property type="entry name" value="UPF0173"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="2">
        <location>
            <begin position="9"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="228" mass="24481" checksum="21D5C3EC7AA164D6" modified="2016-01-20" version="1">MSTQLTWYGHAALGLWTGGFHLLVDPFLSGNPAASSPGESLSADYILITHGHGDHVGDALKIARRCGAKFISVYEIAEWLKKQGFDAHGQHLGGGFHHPFGYLKLTLALHGSILPDGSYGGNPAGFLLTTLEGHKIYIAGDTGLFGDMRLIGEEGIDLAVLPIGDNYTMGPADALRAVKLLEPKHVIPYHYNTFGLIQQDAPAWAKQVEAETSTKVHVLQPGDTFELG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQ22</accession>
    <name>A0A0P6XQ22_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_17205</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064286.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17205"/>
    <dbReference type="EnsemblBacteria" id="KPL71427">
        <property type="protein sequence ID" value="KPL71427"/>
        <property type="gene ID" value="ADN00_17205"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044781">
        <property type="term" value="P:bacterial-type flagellum organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022781">
        <property type="entry name" value="Flagellar_biosynth_FliO"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04347">
        <property type="entry name" value="FliO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="67"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL71427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="176" mass="19037" checksum="8E5A1334FBC20A4A" modified="2016-01-20" version="1">MQKIFDLLKQPLRGGRTQKIGLWLAMIALVASVFVGVLLKNSGEATYSFTQEEVTRTSSTAGLALDVFLKLGVVVALIGVSALAARKWMGKGAVWRPAERKMSVEETLNLSPNRALHLVRVGGQVLLIGATDHNVQLLKEITPEMAAEPVGQSAAEFSEYFQVSLDQFEPVSKGQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQK9</accession>
    <name>A0A0P6XQK9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">PadR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_04135</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061696.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79073">
        <property type="protein sequence ID" value="KPL79073"/>
        <property type="gene ID" value="ADN00_04135"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.183"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005149">
        <property type="entry name" value="Tscrpt_reg_PadR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03551">
        <property type="entry name" value="PadR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PadR" evidence="1">
        <location>
            <begin position="14"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="101" mass="11580" checksum="DE0EDD989E2521A3" modified="2016-01-20" version="1">MLRDFFLGIIKIHILYHAVKNPVYGAELTEELGRHGYQISPGTLYPILHGLEKEGLLTSHKTVVEGKQRRYYAATPKGIEALQEARVRVRELVREVILEEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XR01</accession>
    <name>A0A0P6XR01_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Methyltransferase</fullName>
            <ecNumber evidence="3">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_08740</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the N(4)/N(6)-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="3"/>
    <dbReference type="EMBL" id="LGCL01000022">
        <property type="protein sequence ID" value="KPL77687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08740"/>
    <dbReference type="REBASE" id="132870">
        <property type="entry name" value="M.OapP3M1ORF8740P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77687">
        <property type="protein sequence ID" value="KPL77687"/>
        <property type="gene ID" value="ADN00_08740"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1465"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006306">
        <property type="term" value="P:DNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002941">
        <property type="entry name" value="DNA_methylase_N4/N6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001091">
        <property type="entry name" value="RM_Methyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01555">
        <property type="entry name" value="N6_N4_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00508">
        <property type="entry name" value="S21N4MTFRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N6_N4_Mtase" evidence="5">
        <location>
            <begin position="43"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="166"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="172"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU362026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL77687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="295" mass="34210" checksum="3E153D356301E3C6" modified="2016-01-20" version="1">MRETAENYRTKLDIGTKRTCTCAPNNLNCLPAKEWLKSQIGVWQFFYEGRDIRDKNLHPATFPISLAKKVISLFTHEGELVLDPFVGSGTTLVAAQDLNRNAIGFDLQESYIELCVKRLASNNLFNHAQQVAIQDDALHIPNYLERGSVSLIWTSPPYANLLNRKRKNKSRRERNNEQLHKVEQYSQDPRDLGTMPLEDYTKAMGDIYEGLLPLLHPKGHCVINVPDMWWENERITIHVSLINELRKRGYELRNTIIWDRTNIVNKIGIFGYPSNYITMGTTFEYLLDFWRPPET</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XRF2</accession>
    <name>A0A0P6XRF2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_02830</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000013">
        <property type="protein sequence ID" value="KPL79384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79384">
        <property type="protein sequence ID" value="KPL79384"/>
        <property type="gene ID" value="ADN00_02830"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2199"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="301" mass="33229" checksum="B77922EE5A3F7880" modified="2016-01-20" version="1">MESSSLSMQGKSAVVTGATSGIGLASAVALARAGALVIGVGRSPQRCAQAAAHIQHNVPGARVRYLVAELSLQREVRRLAEEIRCVLDEEGFTHLDALVNNAGIVSTHLERTEEGIYLALAVNHLAGFLLTHRLLPLLRAAPFGRVVTVSSASHYRAIFNPKRLNEPIFYNVVWSYKITKLMNVLFTYELNRRESGSAVRAFAVDPGLINTKIGMKDRNWMVRLAWNVRRRGGRPPEVPAQTVLYLCAEEALQTSTEYYWRDLSPKTPSRAARRPGLARDLWQASAELCGLDENNAKKEQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XTJ9</accession>
    <name>A0A0P6XTJ9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_11145</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063090.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76518">
        <property type="protein sequence ID" value="KPL76518"/>
        <property type="gene ID" value="ADN00_11145"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.925"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="55"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="115"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="144" mass="15822" checksum="0CE925BA8450DE67" modified="2016-01-20" version="1">MIFQRNGGQRNPKRSIELLVLISGLFLLSLMGTLRLQQAVENRQYLQTFSGLPPAAYFAASGFLVGLAGLACGLGLWLRRRWAARLTRAVVVLVTAGYWLERLLFGASAAGRADWPFTALASLFLVGYSLLVLASPRQAAYFKE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XU44</accession>
    <name>A0A0P6XU44_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex</fullName>
            <ecNumber evidence="5">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_05155</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + acetyl-CoA = (R)-N(6)-(S(8)-acetyldihydrolipoyl)-L-lysyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:17017"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:10478"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="ChEBI" id="CHEBI:83111"/>
            <dbReference type="EC" id="2.3.1.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 5">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="5"/>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78647.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061905.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05155"/>
    <dbReference type="EnsemblBacteria" id="KPL78647">
        <property type="protein sequence ID" value="KPL78647"/>
        <property type="gene ID" value="ADN00_05155"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1503"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045254">
        <property type="term" value="C:pyruvate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006086">
        <property type="term" value="P:acetyl-CoA biosynthetic process from pyruvate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045257">
        <property type="entry name" value="E2/Pdx1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23151">
        <property type="entry name" value="PTHR23151"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="SSF47005"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4 5" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="6">
        <location>
            <begin position="2"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="7">
        <location>
            <begin position="115"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="7">
        <location>
            <begin position="162"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL78647.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="449" mass="47084" checksum="387E2E559F09D7DC" modified="2016-01-20" version="1">MPVPVIMPKFEMSQETGQIISWYKKEGDAVKKGEAIFSVETDKVTMDVESPGDGVLAGVTAKEGESVPVTTVIAYLLGAGESLPAGGAPAAATPQPAPAAAAAEAPKAPVSAPASATPVAQRMAAANALDLSAVQGSGPKQTITKADVESALARRGEEGKVRATPAARRVAREGGVDLDTVAGSGPRGRVQESDVQDFLSTAPQAAAPAQPQATAQASSADFDTIPLKGMRRTIADRMVASYQSAPHIMFTMSIDVSSLEGLRKRMNEQAAKRGEEKISMTALLTRAVAWTLLRHPRLNSTLTGDEIRQYKTANIGIAVALEDGLIVPVVRNVEKKGVAQLAAEINDLAKRARESRLTPSDVTGGTFTISNLGPFGIEQFTAILNAGQAGILAVGAVQKEVVVVNDEMVIRPIMRMTLSADHRTVDGAVAAQFMADLRSVMENPDLLLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUH3</accession>
    <name>A0A0P6XUH3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NlpC/P60 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_10845</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C40 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063016.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10845"/>
    <dbReference type="EnsemblBacteria" id="KPL77048">
        <property type="protein sequence ID" value="KPL77048"/>
        <property type="gene ID" value="ADN00_10845"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000064">
        <property type="entry name" value="NLP_P60_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041382">
        <property type="entry name" value="SH3_16"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00877">
        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18348">
        <property type="entry name" value="SH3_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="SSF54001"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51935">
        <property type="entry name" value="NLPC_P60"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NlpC/P60" evidence="2">
        <location>
            <begin position="210"/>
            <end position="333"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51935"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="338" mass="37513" checksum="E1B4F7D0D1B40622" modified="2016-01-20" version="1">MREDLEAILKELAERFADTRAHLFEVNVQSLEGNTAVLAGRVLEEATLQALRLALAETLPGLRVVDDGVQVLRQDNPKILSVGTNLTGLYAQPEFGELLSELMYGWALEIVEERGDWAFVRQLDGYLGWAYLPYLTDDLIPVPTHLVMEPVGLLRAEPRANAPLLGRVLGGTSVRLLDLKDGWARVSASPHGWLPTDALRAFEELPETALEKRAQMMQDAARLTGVPYLWGGCSANGIDCSGFAQLLHRWVGIATPRDADMQYRHGKPIEPPFLPGDLLFFGDTDTSRITHVTISLGGWQIIHSSRARNGVYVDDVQSVPHLKESYLRACTYMDDREG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUM5</accession>
    <name>A0A0P6XUM5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HTH deoR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_05215</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061917.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78867">
        <property type="protein sequence ID" value="KPL78867"/>
        <property type="gene ID" value="ADN00_05215"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014036">
        <property type="entry name" value="DeoR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001034">
        <property type="entry name" value="DeoR_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00455">
        <property type="entry name" value="DeoRC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08220">
        <property type="entry name" value="HTH_DeoR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00037">
        <property type="entry name" value="HTHLACR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00420">
        <property type="entry name" value="HTH_DEOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51000">
        <property type="entry name" value="HTH_DEOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH deoR-type" evidence="3">
        <location>
            <begin position="7"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL78867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="262" mass="29407" checksum="4CDC69574D79E36B" modified="2016-01-20" version="1">MKKLLFREERLRLIMETIYEQKSVVVGELAEKFGKSASSIRLDLAELESRGLISRTHGGAILAEESAKDLVLNKKYLQYRLETYKEEKERIGKIAADMIQDGDSVMIDGGTTNFYVAKNLHKKRGLTIITTSVFLFPVLWEIPDATIYLAGGLLHREFEEMYGDIAQESILRFKPDHTIIGIDGLSIEQGLTSTEPIMAIAKRQMISVSKDIIVVSDSSKFGKVCLLSVSSLKDVNKIVTDDKVSKEYVDRIEKVGPKVYLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XX72</accession>
    <name>A0A0P6XX72_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GTPase HflX</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">GTP-binding protein HflX</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">hflX</name>
        <name evidence="10" type="ORF">ADN00_00950</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">GTPase that associates with the 50S ribosomal subunit and may have a role during protein synthesis or ribosome biogenesis.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer. Associates with the 50S ribosomal subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="5">May associate with membranes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the TRAFAC class OBG-HflX-like GTPase superfamily. HflX GTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061075.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00950"/>
    <dbReference type="EnsemblBacteria" id="KPL81121">
        <property type="protein sequence ID" value="KPL81121"/>
        <property type="gene ID" value="ADN00_00950"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3588"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01878">
        <property type="entry name" value="HflX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11060">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00900">
        <property type="entry name" value="GTPase_HflX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030394">
        <property type="entry name" value="G_HFLX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006073">
        <property type="entry name" value="GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032305">
        <property type="entry name" value="GTP-bd_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016496">
        <property type="entry name" value="GTPase_HflX"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025121">
        <property type="entry name" value="GTPase_HflX_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042108">
        <property type="entry name" value="GTPase_HflX_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045498">
        <property type="entry name" value="HflX_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10229">
        <property type="entry name" value="PTHR10229"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16360">
        <property type="entry name" value="GTP-bdg_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13167">
        <property type="entry name" value="GTP-bdg_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19275">
        <property type="entry name" value="HflX_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01926">
        <property type="entry name" value="MMR_HSR1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006809">
        <property type="entry name" value="GTP-binding_hflX_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00326">
        <property type="entry name" value="GTP1OBG"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03156">
        <property type="entry name" value="GTP_HflX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51705">
        <property type="entry name" value="G_HFLX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5 6" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 5 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hflx-type G" evidence="9">
        <location>
            <begin position="219"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="185"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="225"/>
            <end position="232"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="232"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="250"/>
            <end position="254"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="252"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="272"/>
            <end position="275"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="338"/>
            <end position="341"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="363"/>
            <end position="365"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR006809-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR006809-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL81121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="447" mass="49623" checksum="6F50A896A10C89D0" modified="2016-01-20" version="1">MAKKSTETTDRPKERAFLVGVEIRSEEHLLSLEDSLEELSLLADTAGLVVVGEATQRLDRPYANTYIGSGKVEEIKALVEDCLAEVVIFDNELSPRHLRELEKEFGTAVRIIDRTALILDIFALHANTREGALQVELAQYEYRLPRLTRAWTHLARQAGGGGGRSGSVGGVGLRGPGETQLEVDRREIGRRISNLKSELEKIRAHRSRYRANRRRSQIPVIALVGYTNAGKSTLLNRLSNAGVYVADQLFATLDPTTRRVELPGGQVVLFTDTVGFIQKLPTQLIAAFRATLEEIAEADLVLHIVDITHVNALAQWNAVQLTLKEIGADQIPALTVLNKIDRLPDPQAAMQVLQNFPDALAISALKGQGIDELLALVQKRLYEELLPISVRIPYTEGQLISLFHESGQVERIEHQRGSVMIDGSIPGRYITRYMPFIHSGDLEPEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XXV1</accession>
    <name>A0A0P6XXV1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_01115</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000003">
        <property type="protein sequence ID" value="KPL80823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061123.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01115"/>
    <dbReference type="EnsemblBacteria" id="KPL80823">
        <property type="protein sequence ID" value="KPL80823"/>
        <property type="gene ID" value="ADN00_01115"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1968"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL80823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="248" mass="26341" checksum="23C4FE533C23852D" modified="2016-01-20" version="1">MSNDLKSRSAKPLALVTGAARRLGRAIALGLAAEGYAIGLHYHQSEAEANSLAAEIAASGGECLLLAADLTRPAEIEAMFATVAESGYDLRVLVNSAAEMRHATLEEDTPAAWDATFDLNLRAAWLCARLAFALMRPHGGAIINISDAGAGRPWTGYAAYTVSKAALEALTRLQAKQYAPAVRVNGVAPGLILPSEDLSEEVWQRLNVRLPLQENERCGAVVQAVVFLAQNPYITGEVIAVDGGYRLT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="34" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XY92</accession>
    <name>A0A0P6XY92_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Lon protease</fullName>
            <ecNumber evidence="5 6">3.4.21.53</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">ATP-dependent protease La</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">lon</name>
        <name evidence="14" type="ORF">ADN00_00145</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">ATP-dependent serine protease that mediates the selective degradation of mutant and abnormal proteins as well as certain short-lived regulatory proteins. Required for cellular homeostasis and for survival from DNA damage and developmental changes induced by stress. Degrades polypeptides processively to yield small peptide fragments that are 5 to 10 amino acids long. Binds to DNA in a double-stranded, site-specific manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6 9">
            <text>Hydrolysis of proteins in presence of ATP.</text>
            <dbReference type="EC" id="3.4.21.53"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5 6">Homohexamer. Organized in a ring with a central cavity.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 5 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="induction">
        <text evidence="5">By heat shock.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 6 9 10">Belongs to the peptidase S16 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.53" evidence="5 6"/>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00145"/>
    <dbReference type="EnsemblBacteria" id="KPL81134">
        <property type="protein sequence ID" value="KPL81134"/>
        <property type="gene ID" value="ADN00_00145"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3425"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034605">
        <property type="term" value="P:cellular response to heat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006515">
        <property type="term" value="P:protein quality control for misfolded or incompletely synthesized proteins"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01973">
        <property type="entry name" value="lon_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027543">
        <property type="entry name" value="Lon_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004815">
        <property type="entry name" value="Lon_bac/euk-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008269">
        <property type="entry name" value="Lon_proteolytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027065">
        <property type="entry name" value="Lon_Prtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003111">
        <property type="entry name" value="Lon_prtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046336">
        <property type="entry name" value="Lon_prtase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008268">
        <property type="entry name" value="Peptidase_S16_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10046">
        <property type="entry name" value="PTHR10046"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05362">
        <property type="entry name" value="Lon_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02190">
        <property type="entry name" value="LON_substr_bdg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001174">
        <property type="entry name" value="Lon_proteas"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00464">
        <property type="entry name" value="LON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00763">
        <property type="entry name" value="lon"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51787">
        <property type="entry name" value="LON_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51786">
        <property type="entry name" value="LON_PROTEOLYTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01046">
        <property type="entry name" value="LON_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="evidence at transcript level"/>
    <keyword evidence="5 6 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6 9" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="2 5 6" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5 6" id="KW-0720">Serine protease</keyword>
    <keyword evidence="4 5" id="KW-0346">Stress response</keyword>
    <feature type="domain" description="Lon N-terminal" evidence="13">
        <location>
            <begin position="16"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="domain" description="Lon proteolytic" evidence="12">
        <location>
            <begin position="616"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="798"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 7 9">
        <location>
            <position position="703"/>
        </location>
    </feature>
    <feature type="active site" evidence="5 7 9">
        <location>
            <position position="746"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 8">
        <location>
            <begin position="378"/>
            <end position="385"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01973"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRNR" id="PIRNR001174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR001174-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR001174-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU000591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KPL81134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="818" mass="91574" checksum="E2288ABB00936E68" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y005</accession>
    <name>A0A0P6Y005_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05205</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061915.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78657">
        <property type="protein sequence ID" value="KPL78657"/>
        <property type="gene ID" value="ADN00_05205"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042150">
        <property type="entry name" value="MmRce1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35797">
        <property type="entry name" value="PTHR35797"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="45"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="190"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="221"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="248"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="281"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="311" mass="33707" checksum="85EFE5DA8DB3A802" modified="2016-01-20" version="1">MVETKIDVKRIIIFLAFAFGIAWACGLVIYLTGGLVNSPVLFGNFTLALVLMATLYMGAPMLANILTRLVTREGWADAKLRPQFKRGWPYWLAMWFLPGILTIIGAGVFFLIFPQFFDPELTQLTAMLEASAAAAGQAMPPINPWLIVLVQSVQGLLISPLINGLFTFGEEFGWRAYLQPKLMPLGGRKAMLLMGLIWGVWHAPAILMGHNYGLNYPGAPWLGPLAMIWFCFVIGTMLGWATLKAGSVWPAVIGHAAINGIAAIGALFIQGNPNPLLGPTPVGLVASIGFSLLTLVLFLLPNGLKETELNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y059</accession>
    <name>A0A0P6Y059_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aldolase_II domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13490</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063546.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000031.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13490"/>
    <dbReference type="EnsemblBacteria" id="KPL74846">
        <property type="protein sequence ID" value="KPL74846"/>
        <property type="gene ID" value="ADN00_13490"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.225.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001303">
        <property type="entry name" value="Aldolase_II/adducin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036409">
        <property type="entry name" value="Aldolase_II/adducin_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00596">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01007">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53639">
        <property type="entry name" value="SSF53639"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldolase_II" evidence="1">
        <location>
            <begin position="6"/>
            <end position="190"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="197" mass="21869" checksum="4E8BC554B7747265" modified="2016-01-20" version="1">MANIPEQIVAIARTMFERRLTDMAGGNLSARDGETVYITPRFSGSKRHWQLNPEDILSGPLQGDELLNHPLFSREGKAHLAIYRNFPNCKAVIHAHAFHIQPFVVAEKPIPAVMEATEKFGTVNVVKYAPAHSADLAQYIVEGLRGQDERIQVQAAAVLMPRHGIMVAGKDLYAAVDALERIDTNCWCIMAQRLIGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y0M8</accession>
    <name>A0A0P6Y0M8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Orotate phosphoribosyltransferase</fullName>
            <shortName evidence="7">OPRT</shortName>
            <shortName evidence="7">OPRTase</shortName>
            <ecNumber evidence="7">2.4.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">pyrE</name>
        <name evidence="9" type="ORF">ADN00_06330</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the transfer of a ribosyl phosphate group from 5-phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H(+) + orotidine 5'-phosphate = CO2 + UMP</text>
            <dbReference type="Rhea" id="RHEA:11596"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57538"/>
            <dbReference type="ChEBI" id="CHEBI:57865"/>
            <dbReference type="EC" id="4.1.1.23"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>diphosphate + orotidine 5'-phosphate = 5-phospho-alpha-D-ribose 1-diphosphate + orotate</text>
            <dbReference type="Rhea" id="RHEA:10380"/>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57538"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="EC" id="2.4.2.10"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 7">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 1/2.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2">Pyrimidine metabolism; UMP biosynthesis via de novo pathway; UMP from orotate: step 2/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the purine/pyrimidine phosphoribosyltransferase family. PyrE subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.10" evidence="7"/>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062118.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06330"/>
    <dbReference type="EnsemblBacteria" id="KPL78831">
        <property type="protein sequence ID" value="KPL78831"/>
        <property type="gene ID" value="ADN00_06330"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1768"/>
    <dbReference type="UniPathway" id="UPA00070">
        <property type="reaction ID" value="UER00119"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004588">
        <property type="term" value="F:orotate phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004590">
        <property type="term" value="F:orotidine-5'-phosphate decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006207">
        <property type="term" value="P:'de novo' pyrimidine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044205">
        <property type="term" value="P:'de novo' UMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01208">
        <property type="entry name" value="PyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011995">
        <property type="entry name" value="OMPdecase_type-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001754">
        <property type="entry name" value="OMPdeCOase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023031">
        <property type="entry name" value="OPRT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004467">
        <property type="entry name" value="Or_phspho_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43375">
        <property type="entry name" value="PTHR43375"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00215">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00934">
        <property type="entry name" value="OMPdecase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00336">
        <property type="entry name" value="pyrE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02127">
        <property type="entry name" value="pyrF_sub2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="4 7" id="KW-0665">Pyrimidine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="OMPdecase" evidence="8">
        <location>
            <begin position="17"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="5-phosphoribose 1-diphosphate binding" evidence="7">
        <location>
            <begin position="387"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="361"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="362"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="365"/>
        </location>
        <ligand>
            <name>5-phospho-alpha-D-ribose 1-diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <note>ligand shared between dimeric partners</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="391"/>
        </location>
        <ligand>
            <name>orotate</name>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="419"/>
        </location>
        <ligand>
            <name>orotate</name>
            <dbReference type="ChEBI" id="CHEBI:30839"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01208"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00934"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL78831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="469" mass="50882" checksum="54BA2C3AED674F2E" modified="2016-01-20" version="1">MSFFEKLEAAIERNNSLLCVGLDPQLESLKGVSDPAEIESQLVAWGQRIIEQTHEVVCCYKPNFAFYEQYGLAGLRALQRTVSLIPEGIPHLLDAKRGDIGSTAQAYANAAYQQWHADAVTLSPYLGEDSIKPFLKTEGKAAFILCHTSNPSAAQVQHHGQPALYELIAETSKTWGGADQIGFVVGATQPEAMAAVRARCPEHWILAPGVGAQGGDLEAALKAGLRPDGKGLILPVSRGVIAAADPRQAAIELRDQINTLRQQAATFSKARSYKEKLVASLFETGCIKFGQFTLASGKSSPIYIDLRRVISFPALFEMVVNGYAQLARTISYDLLAGVPYAALPATAVVAARLQQPMIYPRKEVKQYGTGQAIEGAYTPGQTAVMLEDVVTSGGSIIKAAETLQQAGLQVRDVIVLVDREQGGREELHRSANLTLHAVVTIREILTLLREQNLIDAPTYQEVWAYLEQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y0Y4</accession>
    <name>A0A0P6Y0Y4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_05870</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05870"/>
    <dbReference type="EnsemblBacteria" id="KPL78877">
        <property type="protein sequence ID" value="KPL78877"/>
        <property type="gene ID" value="ADN00_05870"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="1"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="27"/>
            <end position="34"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL78877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="257" mass="28988" checksum="3F1644B532A901DD" modified="2016-01-20" version="1">MGGRQKVNVLQDIDFEANEGSFVCILGPSGCGKSTLFNVIAGLISPTRGNIYLDGQSINGKTGLVGYMFQKDLLLPWRSIIENIYLGAEIQKRNMPESAAKAQMLVEKYGLSGFEDYYPKFLSGGMRQRAAFLRTMMLDNKVMLLDEPFGALDAQTRLSMQEWLHEVWRDSKKTIIFITHDVDEAIFLAEKVLVLSHRPSTILEYVDIPLPENRNYEMMGEPEIIKLRSEMFKIIRQESQKSLGGKDAGVESDPVIL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y2F7</accession>
    <name>A0A0P6Y2F7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_04440</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061748.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79115">
        <property type="protein sequence ID" value="KPL79115"/>
        <property type="gene ID" value="ADN00_04440"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00037">
        <property type="entry name" value="Fer4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12838">
        <property type="entry name" value="Fer4_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="27"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="67"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="178"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="209"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL79115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="324" mass="36309" checksum="9EF2690217EB095B" modified="2016-01-20" version="1">MSARGLTKKQTTSAEIVLERPMVTRHYKMVWDLDRCVGCQIGPAVCPKDAVKHIPAELEGGRMVKRAGVDIDAEACIFCGMCAVMCPTQAISMTINGEPEIPIIDYEAFPKLIESTVFERELFDFGLKDFVVNNCPTHVISYNAEADTMEVDDAHCIRCRQCEVASSGAFQVVQPWEGLVRLQRDKCVEGCLACADICPTRALHIDDDGELTLADYYCIKCGACMQICPVKPEVEKYTTTFEVKEIEVKRERERVMNAHDLPIWVERWRVKHSPVDSGAWRAALLDMADDKAGAVEIDRTRALRRRDLLKALAGGKAMLERAKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y4K0</accession>
    <name>A0A0P6Y4K0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">HIT family hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_11205</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063102.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76528">
        <property type="protein sequence ID" value="KPL76528"/>
        <property type="gene ID" value="ADN00_11205"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01275">
        <property type="entry name" value="FHIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039383">
        <property type="entry name" value="FHIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01230">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="SSF54197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIT" evidence="4">
        <location>
            <begin position="23"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Histidine triad motif" evidence="3">
        <location>
            <begin position="118"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-AMP-histidine intermediate" evidence="2">
        <location>
            <position position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR639383-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL76528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="166" mass="19121" checksum="72BA1B8F0F48A5EE" modified="2016-01-20" version="1">MDYLWSPWRMDYIKSDKTPHQCVFCEALKQNNDEEMLILTRAEHSFIILNRYPYNNGHLMVVPYAHKATLNELDAETRAEMMELLSKVESMLKMEYRPEGINMGVNIGAAAGAGVADHIHFHVVPRWNGDVNFMGAVALTRVLPEDLWQTYQRMKKAWEVIEAGGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y613</accession>
    <name>A0A0P6Y613_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_01120</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000003">
        <property type="protein sequence ID" value="KPL80824.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061124.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01120"/>
    <dbReference type="EnsemblBacteria" id="KPL80824">
        <property type="protein sequence ID" value="KPL80824"/>
        <property type="gene ID" value="ADN00_01120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004659">
        <property type="term" value="F:prenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901663">
        <property type="term" value="P:quinone biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000537">
        <property type="entry name" value="UbiA_prenyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026046">
        <property type="entry name" value="UBIAD1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13929">
        <property type="entry name" value="PTHR13929"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01040">
        <property type="entry name" value="UbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="44"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="118"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="180"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="222"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="247"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="278"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL80824.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="301" mass="33358" checksum="6D888145C1880E39" modified="2016-01-20" version="1">MDDAKQVRTVVISYARLPMLAMSVLFYFLGASLAHFLGDVVNPAQFFGGMFIILLVFLFSGWIKGYYDTQEDMQNRLGLEAFSPKAFLLAKKLLWQGSLASLVVAAVLVVFMGVQRLLNVPGSTLLLLIFGISYIYSVPPLRLVYRGYGELATAVVLANLTPALSFTLQSGELHRLVGMVTFPLTALLLAFQLARSLELYASDMKYKRKTMMVALGWQRGMTLHNILVLGAYVLLGAAALFNLPWGITWPVLLTLPLALGLVWLMIRITNGAKPAWKLLTFMSASLLVLSTYLFTYSLWIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y6J8</accession>
    <name>A0A0P6Y6J8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">GHMP kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_00515</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060998.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00515"/>
    <dbReference type="EnsemblBacteria" id="KPL81053">
        <property type="protein sequence ID" value="KPL81053"/>
        <property type="gene ID" value="ADN00_00515"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3497"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001174">
        <property type="entry name" value="Galkinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013750">
        <property type="entry name" value="GHMP_kinase_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036554">
        <property type="entry name" value="GHMP_kinase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006204">
        <property type="entry name" value="GHMP_kinase_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014606">
        <property type="entry name" value="Heptose_7-P_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08544">
        <property type="entry name" value="GHMP_kinases_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00288">
        <property type="entry name" value="GHMP_kinases_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036406">
        <property type="entry name" value="Hept_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00960">
        <property type="entry name" value="LMBPPROTEIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55060">
        <property type="entry name" value="SSF55060"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 6" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="GHMP_kinases_N" evidence="4">
        <location>
            <begin position="87"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="domain" description="GHMP_kinases_C" evidence="5">
        <location>
            <begin position="228"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL81053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="329" mass="36511" checksum="5727A04CC633F6CC" modified="2016-01-20" version="1">MIIVQTPLRVSLFGGGTDFYSYFSQHGGCVLSAAIDKYIFVTIKQRFDKKIRVGYTKTEMVDTIEEVQHELIREALRKTGIKQGIEITTMGDIPSAGSGLGSSSTVTVGALQAMYTYLGEIVTADRLAQEACEIEIDILKKPIGIQDQYIVSYGGLRLIEFTKEGVITSRRLNLGEKGYRLLSNNLMLFFTGITRSASSILQEQNNKVTDNHAYLQQLKQFAYDAFNLIENGNVDSIGEMLHESWQIKKKLASNITNGPIEDYYEAARKAGAIGGKISGAGGGGFLLLYCPANKQENVRQVLSGLQELPFSIERDGTKVIFNYRRVDMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y966</accession>
    <name>A0A0P6Y966_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Pyridoxal 5'-phosphate synthase subunit PdxS</fullName>
            <shortName evidence="3">PLP synthase subunit PdxS</shortName>
            <ecNumber evidence="3">4.3.3.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Pdx1</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">pdxS</name>
        <name evidence="6" type="ORF">ADN00_07475</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5-phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>aldehydo-D-ribose 5-phosphate + D-glyceraldehyde 3-phosphate + L-glutamine = H(+) + 3 H2O + L-glutamate + phosphate + pyridoxal 5'-phosphate</text>
            <dbReference type="Rhea" id="RHEA:31507"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58273"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
            <dbReference type="EC" id="4.3.3.6"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3">Cofactor biosynthesis; pyridoxal 5'-phosphate biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">In the presence of PdxT, forms a dodecamer of heterodimers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the PdxS/SNZ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.3.6" evidence="3"/>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062357.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07475"/>
    <dbReference type="EnsemblBacteria" id="KPL78293">
        <property type="protein sequence ID" value="KPL78293"/>
        <property type="gene ID" value="ADN00_07475"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3320"/>
    <dbReference type="UniPathway" id="UPA00245"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036381">
        <property type="term" value="F:pyridoxal 5'-phosphate synthase (glutamine hydrolysing) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042823">
        <property type="term" value="P:pyridoxal phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04727">
        <property type="entry name" value="pdxS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01824">
        <property type="entry name" value="PdxS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001852">
        <property type="entry name" value="PdxS/SNZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033755">
        <property type="entry name" value="PdxS/SNZ_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31829">
        <property type="entry name" value="PTHR31829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01680">
        <property type="entry name" value="SOR_SNZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF029271">
        <property type="entry name" value="Pdx1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00343">
        <property type="entry name" value="TIGR00343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01235">
        <property type="entry name" value="PDXS_SNZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51129">
        <property type="entry name" value="PDXS_SNZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0704">Schiff base</keyword>
    <feature type="domain" description="SOR_SNZ" evidence="5">
        <location>
            <begin position="18"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="D-ribose 5-phosphate binding" evidence="3">
        <location>
            <begin position="246"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="active site" description="Schiff-base intermediate with D-ribose 5-phosphate" evidence="3">
        <location>
            <position position="92"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="164"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="176"/>
        </location>
        <ligand>
            <name>D-glyceraldehyde 3-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="225"/>
        </location>
        <ligand>
            <name>D-ribose 5-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:78346"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01680"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL78293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="305" mass="32927" checksum="85A85C09CE9DA9CC" modified="2016-01-20" version="1">MQFYSPRRYPLEQQSGTFAVKKGLAQMLKGGVIMDVVTPEHARIAEDAGACAVMALERVPADIRASGGVARMSDPELILQIMDSVTIPVMAKCRIGHFVEAQILESLGVDYIDESEVLTPADDQNHIYKHNFQVPFVCGSRNLGEALRRIGEGAAMIRTKGEAGTGDVIEAVRHARQIMGDIRHLQTLQDEEVMAYAKQIGAPYELVLEVRQLGRLPVVNFAAGGVATPADAALMMQLGVDGVFVGSGIFKSGDPAKRAAAIVKAVTHYQDPAILAEVSRNLGEPMVGRQVTEIPEAQRIAGRGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y9A8</accession>
    <name>A0A0P6Y9A8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_07770</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062411.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78339">
        <property type="protein sequence ID" value="KPL78339"/>
        <property type="gene ID" value="ADN00_07770"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="216" mass="24437" checksum="75C25ED5655E838D" modified="2016-01-20" version="1">MTSDPRLGFIFHKPKDPTAPGAPRLDIVIQEVPSLHHFDPEKIILNIITADETISKVTLRHPFYALRNEIRVAAGQVAMIDRVGKRVEAFTFGGELLVESNETYTVFSLESPAPILYLDDMTSLQMRLVDEVKIIFAQRRAAWLHDLSRFEKRLAQVDPLMLYAACLIKLEANLKKYPCSGTDLVSRLGAVVKQEIKRLKSEGAWPPFVKPIEELI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YA47</accession>
    <name>A0A0P6YA47_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">L-serine dehydratase</fullName>
            <ecNumber evidence="9">4.3.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">ADN00_05450</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 9">
            <text>L-serine = NH4(+) + pyruvate</text>
            <dbReference type="Rhea" id="RHEA:19169"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:33384"/>
            <dbReference type="EC" id="4.3.1.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 9">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the iron-sulfur dependent L-serine dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.17" evidence="9"/>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061962.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05450"/>
    <dbReference type="EnsemblBacteria" id="KPL78695">
        <property type="protein sequence ID" value="KPL78695"/>
        <property type="gene ID" value="ADN00_05450"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1565"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003941">
        <property type="term" value="F:L-serine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.90">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029009">
        <property type="entry name" value="ASB_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004644">
        <property type="entry name" value="Fe-S_L-Ser_mono"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005130">
        <property type="entry name" value="Ser_deHydtase-like_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005131">
        <property type="entry name" value="Ser_deHydtase_bsu"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03313">
        <property type="entry name" value="SDH_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03315">
        <property type="entry name" value="SDH_beta"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143548">
        <property type="entry name" value="SSF143548"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00720">
        <property type="entry name" value="sda_mono"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="9" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="6 9" id="KW-0408">Iron</keyword>
    <keyword evidence="7 9" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="8 9" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 9" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SDH_beta" evidence="12">
        <location>
            <begin position="3"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="domain" description="SDH_beta" evidence="12">
        <location>
            <begin position="70"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="domain" description="SDH_alpha" evidence="11">
        <location>
            <begin position="156"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU366059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF03313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF03315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KPL78695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="411" mass="43827" checksum="6B00EBB1D4960D84" modified="2016-01-20" version="1">MESIQSLFRVGHGPSSSHTIGPQRAAEDFYKRVPHASSIRVTLFGSLAATGKGHLTDLAITRALAPCPVELVWKPDELLPAHPNGMRFEALDEQGQQISVWQGYSVGGGAILEEGQKPSEAASVYPLGSMRDIMKLCTQTGQAFWEYVETQEGPEIWGFLSFIWQTMQQSIQRGLQAEGVLPGGLGVSRKASVYYRKIKLNGANFLKHGYLPAYALAVAEENATGGLIVTAPTCGSGGVLPSVLKHVQDHMDCSEAVILRALATAGLIGNLIKHNASISGAEVGCQGEIGSACAMAAAAATQILGGTIRQIEYAAEMGLEHHLGLTCDPVNGLVQIPCIERNAFAATRAMDCASYALYSDGTHRVSFDEVLQVMKQTGHDLPSLYRETASGGLALTYRFPPQSPADTRSGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YAQ6</accession>
    <name>A0A0P6YAQ6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">HDc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_03550</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78979.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061588.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03550"/>
    <dbReference type="EnsemblBacteria" id="KPL78979">
        <property type="protein sequence ID" value="KPL78979"/>
        <property type="gene ID" value="ADN00_03550"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031123">
        <property type="term" value="P:RNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05398">
        <property type="entry name" value="NT_ClassII-CCAase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032810">
        <property type="entry name" value="CCA-adding_enz_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006674">
        <property type="entry name" value="HD_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002646">
        <property type="entry name" value="PolA_pol_head_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032828">
        <property type="entry name" value="PolyA_RNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01966">
        <property type="entry name" value="HD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01743">
        <property type="entry name" value="PolyA_pol"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12627">
        <property type="entry name" value="PolyA_pol_RNAbd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13735">
        <property type="entry name" value="tRNA_NucTran2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00471">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HDc" evidence="5">
        <location>
            <begin position="250"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU003953"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL78979.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="512" mass="57281" checksum="EE6AA9301A71C23A" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="33" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YBL0</accession>
    <name>A0A0P6YBL0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Phenylalanine--tRNA ligase beta subunit</fullName>
            <ecNumber evidence="14">6.1.1.20</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="14">Phenylalanyl-tRNA synthetase beta subunit</fullName>
            <shortName evidence="14">PheRS</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="primary">pheT</name>
        <name evidence="19" type="ORF">ADN00_03025</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="19 20" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="19 20">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 14">
            <text>ATP + L-phenylalanine + tRNA(Phe) = AMP + diphosphate + H(+) + L-phenylalanyl-tRNA(Phe)</text>
            <dbReference type="Rhea" id="RHEA:19413"/>
            <dbReference type="Rhea" id="RHEA-COMP:9668"/>
            <dbReference type="Rhea" id="RHEA-COMP:9699"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58095"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78531"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.20"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="14">Binds 2 magnesium ions per tetramer.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 14">Tetramer of two alpha and two beta subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 14">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.20" evidence="14"/>
    <dbReference type="EMBL" id="LGCL01000014">
        <property type="protein sequence ID" value="KPL79317.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061483.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000014.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03025"/>
    <dbReference type="EnsemblBacteria" id="KPL79317">
        <property type="protein sequence ID" value="KPL79317"/>
        <property type="gene ID" value="ADN00_03025"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2016"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004826">
        <property type="term" value="F:phenylalanine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006432">
        <property type="term" value="P:phenylalanyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00769">
        <property type="entry name" value="PheRS_beta_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02796">
        <property type="entry name" value="tRNA_bind_bactPheRS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.930.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00283">
        <property type="entry name" value="Phe_tRNA_synth_beta1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045864">
        <property type="entry name" value="aa-tRNA-synth_II/BPL/LPL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005146">
        <property type="entry name" value="B3/B4_tRNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005121">
        <property type="entry name" value="Fdx_antiC-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036690">
        <property type="entry name" value="Fdx_antiC-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045060">
        <property type="entry name" value="Phe-tRNA-ligase_IIc_bsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004532">
        <property type="entry name" value="Phe-tRNA-ligase_IIc_bsu_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020825">
        <property type="entry name" value="Phe-tRNA_synthase-like_B3/B4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041616">
        <property type="entry name" value="PheRS_beta_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002547">
        <property type="entry name" value="tRNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033714">
        <property type="entry name" value="tRNA_bind_bactPheRS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005147">
        <property type="entry name" value="tRNA_synthase_B5-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10947">
        <property type="entry name" value="PTHR10947"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03483">
        <property type="entry name" value="B3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03484">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03147">
        <property type="entry name" value="FDX-ACB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01588">
        <property type="entry name" value="tRNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17759">
        <property type="entry name" value="tRNA_synthFbeta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00873">
        <property type="entry name" value="B3_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00874">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00896">
        <property type="entry name" value="FDX-ACB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54991">
        <property type="entry name" value="SSF54991"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55681">
        <property type="entry name" value="SSF55681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00472">
        <property type="entry name" value="pheT_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51483">
        <property type="entry name" value="B5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51447">
        <property type="entry name" value="FDX_ACB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50886">
        <property type="entry name" value="TRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 14" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="9 14" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="14" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 14" id="KW-0436">Ligase</keyword>
    <keyword evidence="10 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 14" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12 14" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 15" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 15" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="TRNA-binding" evidence="16">
        <location>
            <begin position="56"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="B5" evidence="18">
        <location>
            <begin position="438"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="domain" description="FDX-ACB" evidence="17">
        <location>
            <begin position="748"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="491"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="501"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="504"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="505"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS50886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="17">
        <source>
            <dbReference type="PROSITE" id="PS51447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="PROSITE" id="PS51483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KPL79317.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="842" mass="92958" checksum="F34299781E9BEE75" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YEM1</accession>
    <name>A0A0P6YEM1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01480</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80542.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061188.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01480"/>
    <dbReference type="EnsemblBacteria" id="KPL80542">
        <property type="protein sequence ID" value="KPL80542"/>
        <property type="gene ID" value="ADN00_01480"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1051"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00376">
        <property type="entry name" value="MerR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH merR-type" evidence="1">
        <location>
            <begin position="5"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="domain" description="HTH merR-type" evidence="1">
        <location>
            <begin position="128"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80542.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="254" mass="28928" checksum="AB3E463D5CD5790D" modified="2016-01-20" version="1">MPYKRLSTKKIADIVGVHPNTVRLYESVGFLPPIPRAANGYRQYTEAHIDQMRLARKVMGSPWLGRPIRRMGVELVLTAAKGDLSEAQWLAYQHLKLVETELAQAEQAAEVLARWAAGERTQEDGQPALQIKEAARALNLTVDVLRNWERNGLIEVPRNPRNRYRQYGAPQMEHLRVLRILLRSGYSTMAVLRAMLRMQGEGGSSGDVLRQVLDTPREDEDVLTAADRWITSLRSQQQRALEIIELVEEMLKKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YF83</accession>
    <name>A0A0P6YF83_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Molybdopterin molybdenumtransferase</fullName>
            <ecNumber evidence="7">2.10.1.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_01125</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Catalyzes the insertion of molybdate into adenylated molybdopterin with the concomitant release of AMP.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>adenylyl-molybdopterin + H(+) + molybdate = AMP + H2O + Mo-molybdopterin</text>
            <dbReference type="Rhea" id="RHEA:35047"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:36264"/>
            <dbReference type="ChEBI" id="CHEBI:62727"/>
            <dbReference type="ChEBI" id="CHEBI:71302"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.10.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 7">Cofactor biosynthesis; molybdopterin biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 7">Belongs to the MoeA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.10.1.1" evidence="7"/>
    <dbReference type="EMBL" id="LGCL01000003">
        <property type="protein sequence ID" value="KPL80825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061125.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01125"/>
    <dbReference type="EnsemblBacteria" id="KPL80825">
        <property type="protein sequence ID" value="KPL80825"/>
        <property type="gene ID" value="ADN00_01125"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1970"/>
    <dbReference type="UniPathway" id="UPA00344"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061599">
        <property type="term" value="F:molybdopterin molybdotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006777">
        <property type="term" value="P:Mo-molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032324">
        <property type="term" value="P:molybdopterin cofactor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00887">
        <property type="entry name" value="MoeA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.340.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.980.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036425">
        <property type="entry name" value="MoaB/Mog-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001453">
        <property type="entry name" value="MoaB/Mog_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008284">
        <property type="entry name" value="MoCF_biosynth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038987">
        <property type="entry name" value="MoeA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005111">
        <property type="entry name" value="MoeA_C_domain_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036688">
        <property type="entry name" value="MoeA_C_domain_IV_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005110">
        <property type="entry name" value="MoeA_linker/N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036135">
        <property type="entry name" value="MoeA_linker/N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10192">
        <property type="entry name" value="PTHR10192"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00994">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03454">
        <property type="entry name" value="MoeA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03453">
        <property type="entry name" value="MoeA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00852">
        <property type="entry name" value="MoCF_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53218">
        <property type="entry name" value="SSF53218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63867">
        <property type="entry name" value="SSF63867"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63882">
        <property type="entry name" value="SSF63882"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00177">
        <property type="entry name" value="molyb_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01079">
        <property type="entry name" value="MOCF_BIOSYNTHESIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0500">Molybdenum</keyword>
    <keyword evidence="6 7" id="KW-0501">Molybdenum cofactor biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MoCF_biosynth" evidence="8">
        <location>
            <begin position="188"/>
            <end position="327"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00002901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00010763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU365090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL80825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="411" mass="43749" checksum="A6DEE98AB0658B01" modified="2016-01-20" version="1">MPEFLKLTAPDEALKRFMSHLPAAQPRRETLPVLEAAGRVLASDVYALEALPSFRRSTVDGFAVQASSTFGASDSLPIYMNVVGESQMGAEPNFKVGKGQAAVIHTGGMLPEGANAVVMMEYTQEARAGEVEVQRAVSVGENVIEPGEDVKPGELLLEAGKELSPAVVGGLMSQGIAEVEVVKPPRIGILSSGDEVVDPLQVPLPGQVRDVNSYSLSALVQRFGGEPVRFGISSDREEDMRARARSAMDACDALVITAGSSASVRDLTARILAEMGEPGVLVHGIRIRPGKPTILAVCDGKPAIGLPGNPVSALVVGSLFIKPMIYHLTGRKTTVPVAYLQARLSTNTPSQAGKEEWFPVSLRQDERGWIAEPIFYKSNLIFALAKADGLIRVPLDANGLEAGQVVEVYFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YFU2</accession>
    <name>A0A0P6YFU2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_00645</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL81072">
        <property type="protein sequence ID" value="KPL81072"/>
        <property type="gene ID" value="ADN00_00645"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL81072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="132" mass="14846" checksum="80D18B3772A7ADA8" modified="2016-01-20" version="1">MVLGNPSFISDRGSDPKNHRRTRENINFFCLLPYIPGYSRSSIIYCYTAVVIAISLVELSPHYETDIGINSVMDQQNLSFVGPSYSHLQLFLKRFNFLNWNSGVKPSPVQAPIFKVSCLQALAQALSVFQLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GKL9</accession>
    <name>A0A0N8GKL9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Coenzyme A biosynthesis bifunctional protein CoaBC</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">DNA/pantothenate metabolism flavoprotein</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Phosphopantothenoylcysteine synthetase/decarboxylase</fullName>
            <shortName evidence="3">PPCS-PPCDC</shortName>
        </alternativeName>
        <domain>
            <recommendedName>
                <fullName evidence="3">Phosphopantothenoylcysteine decarboxylase</fullName>
                <shortName evidence="3">PPC decarboxylase</shortName>
                <shortName evidence="3">PPC-DC</shortName>
                <ecNumber evidence="3">4.1.1.36</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="3">CoaC</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="3">Phosphopantothenate--cysteine ligase</fullName>
                <ecNumber evidence="3">6.3.2.5</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="3">CoaB</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="3">Phosphopantothenoylcysteine synthetase</fullName>
                <shortName evidence="3">PPC synthetase</shortName>
                <shortName evidence="3">PPC-S</shortName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="3" type="primary">coaBC</name>
        <name evidence="7" type="ORF">ADN00_18635</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Catalyzes two sequential steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine. In the second step the latter compound is decarboxylated to form 4'-phosphopantotheine.</text>
    </comment>
    <comment type="function">
        <text evidence="4">Catalyzes two steps in the biosynthesis of coenzyme A. In the first step cysteine is conjugated to 4'-phosphopantothenate to form 4-phosphopantothenoylcysteine, in the latter compound is decarboxylated to form 4'-phosphopantotheine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>(R)-4'-phosphopantothenate + CTP + L-cysteine = CMP + diphosphate + H(+) + N-[(R)-4-phosphopantothenoyl]-L-cysteine</text>
            <dbReference type="Rhea" id="RHEA:19397"/>
            <dbReference type="ChEBI" id="CHEBI:10986"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
            <dbReference type="ChEBI" id="CHEBI:59458"/>
            <dbReference type="ChEBI" id="CHEBI:60377"/>
            <dbReference type="EC" id="6.3.2.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>H(+) + N-[(R)-4-phosphopantothenoyl]-L-cysteine = (R)-4'-phosphopantetheine + CO2</text>
            <dbReference type="Rhea" id="RHEA:16793"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:59458"/>
            <dbReference type="ChEBI" id="CHEBI:61723"/>
            <dbReference type="EC" id="4.1.1.36"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
        <text evidence="3">Binds 1 FMN per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 2/5.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 3/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">In the C-terminal section; belongs to the PPC synthetase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">In the N-terminal section; belongs to the HFCD (homo-oligomeric flavin containing Cys decarboxylase) superfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.36" evidence="3"/>
    <dbReference type="EC" id="6.3.2.5" evidence="3"/>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70066.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064547.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18635"/>
    <dbReference type="EnsemblBacteria" id="KPL70066">
        <property type="protein sequence ID" value="KPL70066"/>
        <property type="gene ID" value="ADN00_18635"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3036"/>
    <dbReference type="UniPathway" id="UPA00241">
        <property type="reaction ID" value="UER00353"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004632">
        <property type="term" value="F:phosphopantothenate--cysteine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004633">
        <property type="term" value="F:phosphopantothenoylcysteine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015941">
        <property type="term" value="P:pantothenate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1950">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02225">
        <property type="entry name" value="CoaBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035929">
        <property type="entry name" value="CoaB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005252">
        <property type="entry name" value="CoaBC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007085">
        <property type="entry name" value="DNA/pantothenate-metab_flavo_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036551">
        <property type="entry name" value="Flavin_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003382">
        <property type="entry name" value="Flavoprotein"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04127">
        <property type="entry name" value="DFP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02441">
        <property type="entry name" value="Flavoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102645">
        <property type="entry name" value="SSF102645"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52507">
        <property type="entry name" value="SSF52507"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00521">
        <property type="entry name" value="coaBC_dfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3 4" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="3 4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3 4" id="KW-0288">FMN</keyword>
    <keyword evidence="3 4" id="KW-0436">Ligase</keyword>
    <keyword evidence="2 3 4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavoprotein" evidence="5">
        <location>
            <begin position="8"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="domain" description="DFP" evidence="6">
        <location>
            <begin position="188"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphopantothenoylcysteine decarboxylase" evidence="3">
        <location>
            <begin position="1"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="region of interest" description="Phosphopantothenate--cysteine ligase" evidence="3">
        <location>
            <begin position="193"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="281"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="291"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="329"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="343"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="347"/>
        </location>
        <ligand>
            <name>CTP</name>
            <dbReference type="ChEBI" id="CHEBI:37563"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU364078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF02441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL70066.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="403" mass="41920" checksum="FFB0A0B442BC8545" modified="2016-01-20" version="1">MNNPVQGKKIVLGVTGSIAAYKAAEIASRLTQWGAQVDVVLTESAQKFVTPLTFSSVTGRPAYTEADLWGGQAHVTHIGIARGADLLVIVPASANTLAKLANGIGDNLLSVTHLAASCPLIIAPAMDAGMYSHPATQANVETLQQRGALFVGPAAGHLASGLVGVGRLADPQEILGLIRFTLSRGGPLQGKKVVITAGGTREPIDPVRVITNRSSGRQGYAVAQAALDAGAQVTLITTPTQLPLPYGAEVLSVETAAQMGDAVLSASAQADALIMSAAVADFQPVQAAPQKIKKSGAPPAIELRPTTDILSAVAAQRQTLQRPRVVIGFAAESQNLLENARAKLQAKRLEMIVANDISAADAGFEVNTNRVVFLTPTAEPESLPLLSKSEVAGRIVQRLVEWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GKM9</accession>
    <name>A0A0N8GKM9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_19125</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70146">
        <property type="protein sequence ID" value="KPL70146"/>
        <property type="gene ID" value="ADN00_19125"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3138"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="496"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="291"/>
            <end position="317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="398"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="39"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="57"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="411"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL70146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="522" mass="55444" checksum="E42D91ABA6411FB6" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GL33</accession>
    <name>A0A0N8GL33_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_16875</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064223.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16875"/>
    <dbReference type="EnsemblBacteria" id="KPL71378">
        <property type="protein sequence ID" value="KPL71378"/>
        <property type="gene ID" value="ADN00_16875"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.435"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025302">
        <property type="entry name" value="DUF4162"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13732">
        <property type="entry name" value="DUF4162"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="7"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="39"/>
            <end position="46"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL71378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="306" mass="33765" checksum="7C041EFB3AE83EA2" modified="2016-01-20" version="1">MTHSYTIETFALCKEYGSTVAVKGLSLGVRQGEIFGFLGPNGAGKTTSIKMLLGLTAPTSGSAKLFNQPLGSDENRARVGFLPEHFRFPTWLTGQEFLQFSGQLCKIKRATLEKNMACWLDRVGLSEFQHAQLRTYSKGMLQRIGLAQALVHDPQLVFLDEPTSGLDPVGRRMVRDIMADLREQGKTVFLNSHLLSEVEIICDRVAFIKHGEVLRIETMSELNQGAARVQIQAQGCNAEVLAGLSRRCQVLAAQDSHLTLSVADLETLPEINRYLLENGVRVYSITPEKISLEDLFLQIVGTDGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GLP6</accession>
    <name>A0A0N8GLP6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">tRNA_edit domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_14930</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000036">
        <property type="protein sequence ID" value="KPL73082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063833.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000036.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14930"/>
    <dbReference type="EnsemblBacteria" id="KPL73082">
        <property type="protein sequence ID" value="KPL73082"/>
        <property type="gene ID" value="ADN00_14930"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.960.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036754">
        <property type="entry name" value="YbaK/aa-tRNA-synt-asso_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007214">
        <property type="entry name" value="YbaK/aa-tRNA-synth-assoc-dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04073">
        <property type="entry name" value="tRNA_edit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55826">
        <property type="entry name" value="SSF55826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA_edit" evidence="1">
        <location>
            <begin position="28"/>
            <end position="147"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL73082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="162" mass="18197" checksum="D48F6F4CB9453B02" modified="2016-01-20" version="1">MSNQPSLPASIRFLEQQKVPFRLFHHQRPVESLEDAAVQRGQSPEQVIRSILFRLSEQRYFMVLTPGPNQIPWKALRVYWQQSRLTLASREEVLQVTGCEPGTVNPFGLDAEIPVLIENCIFSLPEISLGSGERGTAILIHPQDVLRAVPQAIVVTLDDALC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GLV8</accession>
    <name>A0A0N8GLV8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Isoprenyl transferase</fullName>
            <ecNumber evidence="2">2.5.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_14655</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="2">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the UPP synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.-" evidence="2"/>
    <dbReference type="EMBL" id="LGCL01000035">
        <property type="protein sequence ID" value="KPL73578.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063778.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000035.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14655"/>
    <dbReference type="EnsemblBacteria" id="KPL73578">
        <property type="protein sequence ID" value="KPL73578"/>
        <property type="gene ID" value="ADN00_14655"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2097"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004659">
        <property type="term" value="F:prenyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00475">
        <property type="entry name" value="Cis_IPPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01139">
        <property type="entry name" value="ISPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001441">
        <property type="entry name" value="UPP_synth-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018520">
        <property type="entry name" value="UPP_synth-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036424">
        <property type="entry name" value="UPP_synth-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10291">
        <property type="entry name" value="PTHR10291"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01255">
        <property type="entry name" value="Prenyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64005">
        <property type="entry name" value="SSF64005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00055">
        <property type="entry name" value="uppS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01066">
        <property type="entry name" value="UPP_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0460">Magnesium</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="23"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="67"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="2">
        <location>
            <begin position="192"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="22"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="70"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="22"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="27"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="186"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="205"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL73578.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="252" mass="28682" checksum="970F8F0FE22165A2" modified="2016-01-20" version="1">MANTSKNDEQMKIPTHVGIIMDGNGRWAKSRGLPRLAGHKAGTENLRRVIRACVEFGIQYLTIYAFSTENWGRPKDEVEGLLRILAEVIEKELPELNEQGVQLHHIGRLEDLPENLRQKVNKAIEITKNNQRLVLNVAFNYGGRDEIVCAIKQMMRDGVTPEQVTPDLISSYMFTAGMPDPDLIIRTSGEMRTSNFLIWQASYAEWYVTPTFWPDFDKEELRKALVAFAQRDRRFGKLSEQDATGSKPVNAC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMB6</accession>
    <name>A0A0N8GMB6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Short-chain dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_13470</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13470"/>
    <dbReference type="EnsemblBacteria" id="KPL74842">
        <property type="protein sequence ID" value="KPL74842"/>
        <property type="gene ID" value="ADN00_13470"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL74842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="301" mass="33847" checksum="6DA6DB71C7A20A8E" modified="2016-01-20" version="1">MIKNLNLDPKVCTDEFQHRLVVITGATSGIGYVTAKKYAAHGADLLLVNRSQKKSEELCAELRGEFNTNCSYIISDFSKLSDVHSAARQLAALQRNIDVLIHNAGVYLTKKKLTEDHLEAVFQTNYLSTFILNYYLLEKLKSQNSGRILFVNSEAYRFAVSGLHFDDLFWNQHRYSGLKSYGAAKLAQLLLMIKLNNYYQGTGVTVNAMHPGNVKTNSGQDNGWLYKKFKSIFIDRSARPLEVAAEALYYLGVSSELDHVSGKFFNLTTIEEPAPPALDINAAEKLWKISIDLSDLYEKSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMH3</accession>
    <name>A0A0N8GMH3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_12975</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000028">
        <property type="protein sequence ID" value="KPL75298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063448.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000028.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12975"/>
    <dbReference type="EnsemblBacteria" id="KPL75298">
        <property type="protein sequence ID" value="KPL75298"/>
        <property type="gene ID" value="ADN00_12975"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051607">
        <property type="term" value="P:defense response to virus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005537">
        <property type="entry name" value="RAMP_III_fam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03787">
        <property type="entry name" value="RAMPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0051">Antiviral defense</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL75298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="235" mass="25322" checksum="EE145DC9828C22C9" modified="2016-01-20" version="1">MILINYSIEFQTPFRVGTGMGQAGFIDNTTIRNRDGLAYIPGSTIKGRARAAALKLAPSFDISTHSTTSDQTGCLVTQPDGPCAICRIFGAPQWPGMLSFEKADLHGEISNILKTLDLHETPIKTHAQNYGRLLRTGIGIDRKLRVVVPDRLFTNECVGTKIPFTGRIIGEFPSSSPIELDLALLLAALKSISHLGGGRGRGLGRCEFTFIKIQVDGKEKSLDQLISSLAGGGLK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMR3</accession>
    <name>A0A0N8GMR3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Single-stranded-DNA-specific exonuclease RecJ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ADN00_11695</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the RecJ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063198.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11695"/>
    <dbReference type="EnsemblBacteria" id="KPL76018">
        <property type="protein sequence ID" value="KPL76018"/>
        <property type="gene ID" value="ADN00_11695"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3814"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008409">
        <property type="term" value="F:5'-3' exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001667">
        <property type="entry name" value="DDH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038763">
        <property type="entry name" value="DHH_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003156">
        <property type="entry name" value="DHHA1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004610">
        <property type="entry name" value="RecJ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041122">
        <property type="entry name" value="RecJ_OB"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01368">
        <property type="entry name" value="DHH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02272">
        <property type="entry name" value="DHHA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17768">
        <property type="entry name" value="RecJ_OB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64182">
        <property type="entry name" value="SSF64182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00644">
        <property type="entry name" value="recJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DHH" evidence="7">
        <location>
            <begin position="84"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="domain" description="DHHA1" evidence="8">
        <location>
            <begin position="325"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="domain" description="RecJ_OB" evidence="9">
        <location>
            <begin position="458"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="317"/>
            <end position="344"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019841"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01368"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF17768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL76018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="570" mass="63433" checksum="8B63F63786C462FA" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GN22</accession>
    <name>A0A0N8GN22_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_09820</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09820"/>
    <dbReference type="EnsemblBacteria" id="KPL76890">
        <property type="protein sequence ID" value="KPL76890"/>
        <property type="gene ID" value="ADN00_09820"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001646">
        <property type="entry name" value="5peptide_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13599">
        <property type="entry name" value="Pentapeptide_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="222" mass="24256" checksum="7BA9E28E2BF785EF" modified="2016-01-20" version="1">MKIISRKNIQPPQLPKALPSGSIAALQDEDEVSMVLLSACDMANTSAAHLLFEKVALKRVSLAASQHAKPRFVDCLLEASDLSGIDWEQARFRRVAFLGCRLIGAQLVDAEFEDVTFKECTLENAVFLSANFKAVRFEHCQLREASFESADLPGVVFDDCDLTRADLRQARLSGADFRGSRLDGVQAGAQELRGAIVDSTQAIQIAGLIGLIVKEYGQEVDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNT4</accession>
    <name>A0A0N8GNT4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Proton_antipo_M domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_03590</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78986.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061596.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03590"/>
    <dbReference type="EnsemblBacteria" id="KPL78986">
        <property type="protein sequence ID" value="KPL78986"/>
        <property type="gene ID" value="ADN00_03590"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001750">
        <property type="entry name" value="ND/Mrp_mem"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00361">
        <property type="entry name" value="Proton_antipo_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="104"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="127"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="157"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="187"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="224"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="255"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="283"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="307"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="351"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="386"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="429"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="domain" description="Proton_antipo_M" evidence="3">
        <location>
            <begin position="182"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL78986.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="463" mass="50710" checksum="64185F46E3331EAF" modified="2016-01-20" version="1">MSAPLIWVVFPLGVSVGLWFLNRQRAWTAAIATVVSALLGLLALVLPIDQSIRIGRNLFQIQSTLNLLGRRLVLDQADTTFLVLVFSIGMLWFIGGWIIRAHAYFAPLGLAVLSLLVAAYAVQPFLYAALVIEVVVLLCVPLLLPPGWKAKKGVMRFLIFQTLAMPFILLAGWASSGVEANPANQSLTLQAVVLLGLGFAFLLASFPFYTWLPQMASEADPFSAGFVLSFLPTIALVLFLEFLNSYAWLADYPQLSTAVRLVGIVMVVTSGLWAAFEKNLRRMFGYAVIFENGLALLAISLMREAGFALFATLLIPRMFSLGLWTYSMTLMARRGDMQLSALRGVIYRQPVAGSGLLIAIYTAFGLPLLAGFYGQTSLLLNLAADSLVVVAWFLIGQAGILAAAFRVLVTVLQKDQEEEKVEERWVDTWMVIIGSAGTILFGLAPAWLAEPIQNMLRAFPRLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNU6</accession>
    <name>A0A0N8GNU6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SIS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_04210</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79082.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061709.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04210"/>
    <dbReference type="EnsemblBacteria" id="KPL79082">
        <property type="protein sequence ID" value="KPL79082"/>
        <property type="gene ID" value="ADN00_04210"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901135">
        <property type="term" value="P:carbohydrate derivative metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05006">
        <property type="entry name" value="SIS_GmhA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035461">
        <property type="entry name" value="GmhA/DiaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13580">
        <property type="entry name" value="SIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SIS" evidence="1">
        <location>
            <begin position="33"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79082.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="190" mass="20583" checksum="023F63891806153F" modified="2016-01-20" version="1">METLAYIDTYFGDLKKVIDALPHQTIAAVYEKIDECQRAGKTLFVFGNGGSAATASHMVCDMGKNTRGTAKPRLKIIGLNDNMPTFSAYANDEGYDRVFAEQILSLGNPGDMVLAISGSGNSPNVLEGIKAAKEKGLFTIGWSGFDGGKLKDMVDLALVVPVHDMEQVEDVHMILDHLTTGLLRGRRYNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNU9</accession>
    <name>A0A0N8GNU9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_04390</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061738.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79106">
        <property type="protein sequence ID" value="KPL79106"/>
        <property type="gene ID" value="ADN00_04390"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="68" mass="7697" checksum="3DEDC1B75F2809B0" modified="2016-01-20" version="1">MYNDDQNDFDGYYNGIYDFYDPFYTGEEEQPPHTAASNGSCCCCSAFALPCFFLPAALFIGWRVLSLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNY2</accession>
    <name>A0A0N8GNY2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_02720</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000013">
        <property type="protein sequence ID" value="KPL79370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061425.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000013.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02720"/>
    <dbReference type="EnsemblBacteria" id="KPL79370">
        <property type="protein sequence ID" value="KPL79370"/>
        <property type="gene ID" value="ADN00_02720"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="81"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="105"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="139"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="167"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="218"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="257"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="285"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="309"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="341"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="375"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="15"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL79370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="404" mass="42494" checksum="CB5BECB67EA3499F" modified="2016-01-20" version="1">MASTTLTKTRSKLGLILLAYIAFISLGLPDGLLGVAWPSMRKDFGMPLDALGLMLIASMIGYLTSSFFSGKVMARLGVGRLLAVSCMLTGAGLIGYTLAPAYWLIVALGVVGGLGAGAIDAGINTYIASEHGEGLMQWLHASFGIGVTLGPIIMTAGINLFQTWRTGYLVVGSAQIALAACFAVTAGMWKREDGSAKQEEDKRLLDYKTSMRETVRQVGVWVSVLLFFVYVGVELTLGHWSYSLLTESRGIAPETAGLLAGGYWGMFTVGRVLAGLYAQKAGTDLLLRGSMLSALAGALLLLWNPSDTVSLIGIAVVGFSIAPIFPALVSSTGRRVSARHAANTIGMQISASGLGGALLPALAGALARRISLEVIPVFLVSLIVLLLVLYFASLWMGKRQAALD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNY9</accession>
    <name>A0A0N8GNY9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_02610</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000012">
        <property type="protein sequence ID" value="KPL79426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061404.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000012.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79426">
        <property type="protein sequence ID" value="KPL79426"/>
        <property type="gene ID" value="ADN00_02610"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="557" mass="64789" checksum="F19FD628B50C2E51" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GPC0</accession>
    <name>A0A0N8GPC0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01790</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000005">
        <property type="protein sequence ID" value="KPL80474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80474">
        <property type="protein sequence ID" value="KPL80474"/>
        <property type="gene ID" value="ADN00_01790"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="76"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="101" mass="11820" checksum="7891394D2E9A8A2B" modified="2016-01-20" version="1">MEINLIIAGIFFVIIIEFMKRFQLTTTNNILVRVERKNDRKKVITISGWCYLQLIGVYWIVIGILLKILRLKFENIFLQALLLFLICGAPFVIGKYLLSKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GPC9</accession>
    <name>A0A0N8GPC9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">UDP-glucose 4-epimerase</fullName>
            <ecNumber evidence="5">5.1.3.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_01500</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>UDP-alpha-D-glucose = UDP-alpha-D-galactose</text>
            <dbReference type="Rhea" id="RHEA:22168"/>
            <dbReference type="ChEBI" id="CHEBI:58885"/>
            <dbReference type="ChEBI" id="CHEBI:66914"/>
            <dbReference type="EC" id="5.1.3.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Carbohydrate metabolism; galactose metabolism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the NAD(P)-dependent epimerase/dehydratase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.1.3.2" evidence="5"/>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061192.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01500"/>
    <dbReference type="EnsemblBacteria" id="KPL80546">
        <property type="protein sequence ID" value="KPL80546"/>
        <property type="gene ID" value="ADN00_01500"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1055"/>
    <dbReference type="UniPathway" id="UPA00214"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003978">
        <property type="term" value="F:UDP-glucose 4-epimerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006012">
        <property type="term" value="P:galactose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005886">
        <property type="entry name" value="UDP_G4E"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01179">
        <property type="entry name" value="galE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0520">NAD</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="8">
        <location>
            <begin position="4"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001911"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00007637"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00013189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00018569"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL80546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="338" mass="37556" checksum="D086C484718436B2" modified="2016-01-20" version="1">MKFLITGGAGYIGSTIASALIDSGHTPVILDSLVRGRVEFTRDRIFYQGDIADRALIERIFKEHPDIQATVHCAALIIVPESTAMPYEYYRENVSKSVELFKTLSDLGYGKVVFSSSASLYDTVPGYMVVEDSPLRPGSPYARTKYMMEMVLKDFCAAYNMKGIALRYFNPIGADPKMRTGLQIRYPSLVIGKLVQTALGELDEFLITGTGWPTRDGTGIRDYVHVWDLAQAHVKAITDFDAVFERAGNPTDNYLVINLGTGNGVTVKELLSAFERVYGQEINKREAPPRPGDVAGAYANRDRAKALLGWEPQLSIEQCIADALKWGELRNSILHWDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GPJ9</accession>
    <name>A0A0N8GPJ9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_00855</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00855"/>
    <dbReference type="EnsemblBacteria" id="KPL81106">
        <property type="protein sequence ID" value="KPL81106"/>
        <property type="gene ID" value="ADN00_00855"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009666">
        <property type="entry name" value="Uncharacterised_Ycf35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39638">
        <property type="entry name" value="PTHR39638"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06868">
        <property type="entry name" value="DUF1257"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0934">Plastid</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL81106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="127" mass="14821" checksum="63EB073C0070729C" modified="2016-01-20" version="1">MSHFSRLKTNMVDKEFLLCALQDLNLPYIEGQDLLLDGFQGAQRKVDVLVKFDVGYPIGLRFRSGKYEIIADWFGVMKTTKKEFTQQLQQRYAYHAAIARLTEQGFTLVEEKTEDNQNIRLVLRRMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WKA7</accession>
    <name>A0A0P6WKA7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="14 15">Dihydroxy-acid dehydratase</fullName>
            <shortName evidence="15">DAD</shortName>
            <ecNumber evidence="14 15">4.2.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="primary">ilvD</name>
        <name evidence="16" type="ORF">ADN00_19100</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="15">Functions in the biosynthesis of branched-chain amino acids. Catalyzes the dehydration of (2R,3R)-2,3-dihydroxy-3-methylpentanoate (2,3-dihydroxy-3-methylvalerate) into 2-oxo-3-methylpentanoate (2-oxo-3-methylvalerate) and of (2R)-2,3-dihydroxy-3-methylbutanoate (2,3-dihydroxyisovalerate) into 2-oxo-3-methylbutanoate (2-oxoisovalerate), the penultimate precursor to L-isoleucine and L-valine, respectively.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>(2R)-2,3-dihydroxy-3-methylbutanoate = 3-methyl-2-oxobutanoate + H2O</text>
            <dbReference type="Rhea" id="RHEA:24809"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:49072"/>
            <dbReference type="EC" id="4.2.1.9"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:24810"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15">
            <text>(2R,3R)-2,3-dihydroxy-3-methylpentanoate = (S)-3-methyl-2-oxopentanoate + H2O</text>
            <dbReference type="Rhea" id="RHEA:27694"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:35146"/>
            <dbReference type="ChEBI" id="CHEBI:49258"/>
            <dbReference type="EC" id="4.2.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="15">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="15">Binds 1 [2Fe-2S] cluster per subunit. This cluster acts as a Lewis acid cofactor.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 15">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="13 15">Amino-acid biosynthesis; L-isoleucine biosynthesis; L-isoleucine from 2-oxobutanoate: step 3/4.</text>
    </comment>
    <comment type="pathway">
        <text evidence="12 15">Amino-acid biosynthesis; L-valine biosynthesis; L-valine from pyruvate: step 3/4.</text>
    </comment>
    <comment type="subunit">
        <text evidence="15">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 15">Belongs to the IlvD/Edd family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.9" evidence="14 15"/>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064636.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_19100"/>
    <dbReference type="EnsemblBacteria" id="KPL70143">
        <property type="protein sequence ID" value="KPL70143"/>
        <property type="gene ID" value="ADN00_19100"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3133"/>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00057"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00049">
        <property type="reaction ID" value="UER00061"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004160">
        <property type="term" value="F:dihydroxy-acid dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009099">
        <property type="term" value="P:valine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00012">
        <property type="entry name" value="IlvD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042096">
        <property type="entry name" value="Dihydro-acid_dehy_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004404">
        <property type="entry name" value="DihydroxyA_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000581">
        <property type="entry name" value="DiOHA_6PGluconate_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020558">
        <property type="entry name" value="DiOHA_6PGluconate_deHydtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037237">
        <property type="entry name" value="IlvD/EDD_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00920">
        <property type="entry name" value="ILVD_EDD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143975">
        <property type="entry name" value="SSF143975"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00110">
        <property type="entry name" value="ilvD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00886">
        <property type="entry name" value="ILVD_EDD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00887">
        <property type="entry name" value="ILVD_EDD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 15" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="3 15" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 15" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="7 15" id="KW-0408">Iron</keyword>
    <keyword evidence="8 15" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="9 15" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 15" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="15">
        <location>
            <position position="470"/>
        </location>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="78"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" description="via carbamate group" evidence="15">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="15">
        <location>
            <position position="444"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-carboxylysine" evidence="15">
        <location>
            <position position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00029304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00029436"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00029437"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00029490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00012"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KPL70143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="555" mass="58665" checksum="1DE4EE3B263EEC4E" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WM23</accession>
    <name>A0A0P6WM23_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_17720</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000043">
        <property type="protein sequence ID" value="KPL70884.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064384.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000043.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70884">
        <property type="protein sequence ID" value="KPL70884"/>
        <property type="gene ID" value="ADN00_17720"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003718">
        <property type="entry name" value="OsmC/Ohr_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036102">
        <property type="entry name" value="OsmC/Ohrsf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02566">
        <property type="entry name" value="OsmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82784">
        <property type="entry name" value="SSF82784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70884.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="136" mass="14644" checksum="4629427CE8558282" modified="2016-01-20" version="1">MSSAQVRWIGGGKFVGVDSTQHSVVLSTPSEGIGMKPSEMLLVALASCTAVDVVSILEKRRKPLASLEIQATGEQDADPPWPFRKIHLKYILSGKDITPKDAETAIQLSEEKYCSVAATVRGVAEITTSYEILPLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WM30</accession>
    <name>A0A0P6WM30_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">ADN00_17820</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000043">
        <property type="protein sequence ID" value="KPL70893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064394.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000043.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17820"/>
    <dbReference type="EnsemblBacteria" id="KPL70893">
        <property type="protein sequence ID" value="KPL70893"/>
        <property type="gene ID" value="ADN00_17820"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033479">
        <property type="entry name" value="dCache_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02743">
        <property type="entry name" value="dCache_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0807">Transducer</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="326"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="10">
        <location>
            <begin position="407"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="9">
        <location>
            <begin position="495"/>
            <end position="731"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL70893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="809" mass="86047" checksum="D26ABD55F50195F7" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WM34</accession>
    <name>A0A0P6WM34_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_17870</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S66 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000043">
        <property type="protein sequence ID" value="KPL70902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064404.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000043.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17870"/>
    <dbReference type="EnsemblBacteria" id="KPL70902">
        <property type="protein sequence ID" value="KPL70902"/>
        <property type="gene ID" value="ADN00_17870"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10740">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027461">
        <property type="entry name" value="Carboxypeptidase_A_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027478">
        <property type="entry name" value="LdcA_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040449">
        <property type="entry name" value="Peptidase_S66_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040921">
        <property type="entry name" value="Peptidase_S66C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003507">
        <property type="entry name" value="S66_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30237">
        <property type="entry name" value="PTHR30237"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02016">
        <property type="entry name" value="Peptidase_S66"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17676">
        <property type="entry name" value="Peptidase_S66C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028757">
        <property type="entry name" value="LD-carboxypeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141986">
        <property type="entry name" value="SSF141986"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="SSF52317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_S66" evidence="4">
        <location>
            <begin position="21"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S66C" evidence="5">
        <location>
            <begin position="213"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="119"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="3">
        <location>
            <position position="244"/>
        </location>
    </feature>
    <feature type="active site" description="Charge relay system" evidence="3">
        <location>
            <position position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR028757-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL70902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="344" mass="38205" checksum="A3C59C6A1D4BC09C" modified="2016-01-20" version="1">MTLPTPPLLKPARLQPGDMLAVVSPSFGAAGLFPHRLEMGLRQAEEMGFKVKVMPNARGVMGAVSGTPQQRADDLHAAFLDPEVKAIIAAIGGNHSNHLLPLLDFDLIRAHPKIFMGYSDITVLNVAIHRRTGLVTFNGPAFITDFAEYPAMFDYARDSFQRTLCAAQAPGQIQPAAAWTDEFLDWAEKKDLQRARLMQPSPGWTWLKPGAAEGWLIGGCIESLEHLRGTAFWPDFEGALLYLETSEEKPTPAQVDSMLMDYENMGIFDRIAGLLVGRPMLYSEEEKQQLREVILERTRAYHFPIISDMDFGHTAPLFILPNGCRARVDSQARRFEILEAAVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WN46</accession>
    <name>A0A0P6WN46_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Chemotaxis protein CheY</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_17290</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064302.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17290"/>
    <dbReference type="EnsemblBacteria" id="KPL71441">
        <property type="protein sequence ID" value="KPL71441"/>
        <property type="gene ID" value="ADN00_17290"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.521"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="3"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL71441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="117" mass="12957" checksum="3685B52E505C8F16" modified="2016-01-20" version="1">MTKILIVDDAEFLRVRISKMLTGDGFEVIEADNGLRAVDTYKAQKPDLVLMDITMPEMDGLSALKEIRSFDSAAKVVMLTALGQESVVLEAIKSGAKDFIVKPFERDRVLNAIQKLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WPI9</accession>
    <name>A0A0P6WPI9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_15870</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL71981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL71981">
        <property type="protein sequence ID" value="KPL71981"/>
        <property type="gene ID" value="ADN00_15870"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL71981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="144" mass="16394" checksum="9161ADEDEA55297B" modified="2016-01-20" version="1">MMLSENWSDFDMTPTNTYEIVNGELRISSQVTGKVLWEGKPKGYDVTAVLPIEGLNDYIVLLEWLKSGLENQKNLVRLDPYGNIVWEVGDPPRDVFVGLERGQEPESYTQIMIENSQLIASSYSGFADYINIETGFIFKTEFVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WTB5</accession>
    <name>A0A0P6WTB5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">zf-HC2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_18680</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064556.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18680"/>
    <dbReference type="EnsemblBacteria" id="KPL70075">
        <property type="protein sequence ID" value="KPL70075"/>
        <property type="gene ID" value="ADN00_18680"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041916">
        <property type="entry name" value="Anti_sigma_zinc_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027383">
        <property type="entry name" value="Znf_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13490">
        <property type="entry name" value="zf-HC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="zf-HC2" evidence="1">
        <location>
            <begin position="7"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="84" mass="9691" checksum="E1510888EEA2CEC7" modified="2016-01-20" version="1">MSKKKCCSELLNTINDYLDGELDGEKCRDLEQHLKDCVDCSTITNTMRKTLELYHEAGKQECLPDDVRDRLFACLELGDFKESK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WV65</accession>
    <name>A0A0P6WV65_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_14215</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063688.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000033.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14215"/>
    <dbReference type="EnsemblBacteria" id="KPL74148">
        <property type="protein sequence ID" value="KPL74148"/>
        <property type="gene ID" value="ADN00_14215"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030916">
        <property type="entry name" value="ELWxxDGT_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005754">
        <property type="entry name" value="Sortase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023365">
        <property type="entry name" value="Sortase_dom-sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04203">
        <property type="entry name" value="Sortase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63817">
        <property type="entry name" value="SSF63817"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR04534">
        <property type="entry name" value="ELWxxDGT_rpt"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01076">
        <property type="entry name" value="sortase_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="655" mass="72083" checksum="3E8121E62C695CCF" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZ48</accession>
    <name>A0A0P6WZ48_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_16245</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72035.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16245"/>
    <dbReference type="EnsemblBacteria" id="KPL72035">
        <property type="protein sequence ID" value="KPL72035"/>
        <property type="gene ID" value="ADN00_16245"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132716" evidence="2">
        <location>
            <begin position="25"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="387"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL72035.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="544" mass="58816" checksum="1EC91007C0E69DB8" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZG0</accession>
    <name>A0A0P6WZG0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">5-methylthioadenosine/S-adenosylhomocysteine deaminase</fullName>
            <shortName evidence="1">MTA/SAH deaminase</shortName>
            <ecNumber evidence="1">3.5.4.28</ecNumber>
            <ecNumber evidence="1">3.5.4.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">mtaD</name>
        <name evidence="3" type="ORF">ADN00_15195</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H(+) + H2O + S-adenosyl-L-homocysteine = NH4(+) + S-inosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:20716"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:57985"/>
            <dbReference type="EC" id="3.5.4.28"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H(+) + H2O + S-methyl-5'-thioadenosine = NH4(+) + S-methyl-5'-thioinosine</text>
            <dbReference type="Rhea" id="RHEA:25025"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:48595"/>
            <dbReference type="EC" id="3.5.4.31"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.28" evidence="1"/>
    <dbReference type="EC" id="3.5.4.31" evidence="1"/>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063887.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15195"/>
    <dbReference type="EnsemblBacteria" id="KPL72177">
        <property type="protein sequence ID" value="KPL72177"/>
        <property type="gene ID" value="ADN00_15195"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.741"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090614">
        <property type="term" value="F:5'-methylthioadenosine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050270">
        <property type="term" value="F:S-adenosylhomocysteine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01281">
        <property type="entry name" value="MTA_SAH_deamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033469">
        <property type="entry name" value="CYTH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023512">
        <property type="entry name" value="Deaminase_MtaD/DadD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55154">
        <property type="entry name" value="SSF55154"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="2">
        <location>
            <begin position="60"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="71"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="191"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="218"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL72177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="656" mass="73913" checksum="0FEE3A3F5E4B5259" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZJ6</accession>
    <name>A0A0P6WZJ6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_15625</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063962.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72245">
        <property type="protein sequence ID" value="KPL72245"/>
        <property type="gene ID" value="ADN00_15625"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="137" mass="15549" checksum="6EA5DD23A4CE300E" modified="2016-01-20" version="1">MSDRENVLTQVEKVMSGADPSDLFFDWFCRTSSLKAKGCKLVRKLEQLLNANQKGNRFDPNAVYTIFKNNCPLYGKLYDDIRICDLETGKVLYTIVPSSGFQNDFGTAILWGKDNDFSGPILEGQWKDILAYFSTRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZN7</accession>
    <name>A0A0P6WZN7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_15480</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>2Fe-2S cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49601"/>
        </cofactor>
        <text evidence="6">Binds 1 [2Fe-2S] cluster.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the complex I 24 kDa subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72296.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15480"/>
    <dbReference type="EnsemblBacteria" id="KPL72296">
        <property type="protein sequence ID" value="KPL72296"/>
        <property type="gene ID" value="ADN00_15480"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.798"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03064">
        <property type="entry name" value="TRX_Fd_NuoE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1590">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028431">
        <property type="entry name" value="NADP_DH_HndA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002023">
        <property type="entry name" value="NuoE-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042128">
        <property type="entry name" value="NuoE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041921">
        <property type="entry name" value="NuoE_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43342:SF2">
        <property type="entry name" value="PTHR43342:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000216">
        <property type="entry name" value="NADH_DH_24kDa"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 6" id="KW-0001">2Fe-2S</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="5 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="6">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>[2Fe-2S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:190135"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022714"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000216-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL72296.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="161" mass="17800" checksum="DA6EAC9463DE5D5D" modified="2016-01-20" version="1">MADPKRKVIIDQIIDQNKDLPGNTMVVLNELQSQIGFISEPMQHYVATRFHIPVSVIHGVVTFYSFFTTTPRGRHTVKFCLGTACYVGGIPQLIEKAKQLLSIEPGQTTPDGAITIELCRCVGACSQAPVLMVDDEIIGHVRPNKLPQIFKPLQEEAKETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X244</accession>
    <name>A0A0P6X244_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_14595</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000035">
        <property type="protein sequence ID" value="KPL73567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14595"/>
    <dbReference type="EnsemblBacteria" id="KPL73567">
        <property type="protein sequence ID" value="KPL73567"/>
        <property type="gene ID" value="ADN00_14595"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070573">
        <property type="term" value="F:metallodipeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008257">
        <property type="entry name" value="Pept_M19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10443">
        <property type="entry name" value="PTHR10443"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01244">
        <property type="entry name" value="Peptidase_M19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51365">
        <property type="entry name" value="RENAL_DIPEPTIDASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL73567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="380" mass="41849" checksum="590514E23CA174FA" modified="2016-01-20" version="1">MGALFFSTKKIMHSFIIDAHEDLAYSALTFGRDYRRAAAETRQREAGTQAPVLNGEALLGWPDYQRGQVALVVGSIFTIPARYATGDFETQVFADPRQARVLMRAQVDFYQRLCAENPHQFRLVTNQPDLLDCLAPWRKLCPAAGYAEETRPVGVLMALEGAEGLDSPEAMEEWWQAGVRMAGPVWAGTRFCGGTFEGSGFTREGLRLLEVMAGLGMGLDLAHMRTRPMLEALDRYEGPLAVSHANVRALVREDPNERQLSEETIRGVVERDGVIGVLGYNLFLKPGWRRGDPKQQVGLEWMAAHIDAVCQVAGDARHVGLGSDFDGGFGRQEAPDGVESIADLQKLAALLAERGYNEDEIGAVLGGNWARFVERILPSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X4H5</accession>
    <name>A0A0P6X4H5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SDH_alpha domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_11005</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063062.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11005"/>
    <dbReference type="EnsemblBacteria" id="KPL76494">
        <property type="protein sequence ID" value="KPL76494"/>
        <property type="gene ID" value="ADN00_11005"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.895"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005130">
        <property type="entry name" value="Ser_deHydtase-like_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021144">
        <property type="entry name" value="UPF0597"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30501">
        <property type="entry name" value="PTHR30501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03313">
        <property type="entry name" value="SDH_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006054">
        <property type="entry name" value="UCP006054"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SDH_alpha" evidence="1">
        <location>
            <begin position="179"/>
            <end position="416"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF03313"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="428" mass="44961" checksum="D8044FC63EBD6AA3" modified="2016-01-20" version="1">MELNNLIAAMQAEIELSIGCTEIGCAALAAARASELLEGNPDRVQVEASSYLYKNAANVCVPNTRLRGLDAALALGFILQGSQDGLAILQRANPSAEEAAQQYLRAHSFETHIVNDGLPVFIRLTAQRAGHTALVEIAGEHSHFSEIRLDGSPLLIDPPTAAEGNHFAFQGICPREMVEFIIAQDDQAFAFLIDQARINEAAAQTGLTNPGTSFGPRLHHHPRPADAILNAACQAQAQTAAASEARMLGLPVPVAALTGSGNHGITALLGMYSAAQALGASQAQTARALAITVMITIYVKHSTSRLTTFCGCAVAPAAGIAAGCVYLMGGGFETMQQAMQSLIGTFAGMLCDGAKESCAWKVSTAASAAVQFAHLAMQGAYIPDGNGILGYNLLETFDNLGKLNNPGMLETNRVVMEIIHDNLNRKPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X504</accession>
    <name>A0A0P6X504_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_09915</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062842.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09915"/>
    <dbReference type="EnsemblBacteria" id="KPL76905">
        <property type="protein sequence ID" value="KPL76905"/>
        <property type="gene ID" value="ADN00_09915"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005198">
        <property type="term" value="F:structural molecule activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011747">
        <property type="entry name" value="CHP02241"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010667">
        <property type="entry name" value="Phage_T4_Gp19"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38009">
        <property type="entry name" value="PTHR38009"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06841">
        <property type="entry name" value="Phage_T4_gp19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02241">
        <property type="entry name" value="TIGR02241"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="188" mass="21077" checksum="80918906089C6E22" modified="2016-01-20" version="1">MGLLQKTSSLPKPESVAPGRFTTEEIPVPVYQFAVEIDGETVALFQNVTGMSVKRDVESVPVGGENSFGREFPGRVSYGHITLEVGLSSSDFFWKWMTGGHLDGYAISKDVTLIQRRPQPDPSAAPDEEKIFQVVKYWFFDNAFPVGWKISDLNLDNSENIVIESLELSFDSFSLYTTRGELRTRQQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5A8</accession>
    <name>A0A0P6X5A8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Cyclic nucleotide-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_06950</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062259.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06950"/>
    <dbReference type="EnsemblBacteria" id="KPL78216">
        <property type="protein sequence ID" value="KPL78216"/>
        <property type="gene ID" value="ADN00_06950"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="171"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="199"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="418"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="2">
        <location>
            <begin position="22"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="566" mass="64369" checksum="0ABF47B6E43CC425" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5U7</accession>
    <name>A0A0P6X5U7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Putative [LysW]-L-2-aminoadipate 6-phosphate reductase</fullName>
            <ecNumber evidence="1">1.2.1.103</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">lysY</name>
        <name evidence="3" type="ORF">ADN00_06690</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the NADPH-dependent reduction of [LysW]-aminoadipate 6-phosphate to yield [LysW]-aminoadipate 6-semialdehyde.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[amino-group carrier protein]-C-terminal-N-(1-carboxy-5-oxopentan-1-yl)-L-glutamine + NADP(+) + phosphate = [amino-group carrier protein]-C-terminal-N-(1-carboxy-5-phosphooxy-5-oxopentan-1-yl)-L-glutamine + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:41948"/>
            <dbReference type="Rhea" id="RHEA-COMP:9712"/>
            <dbReference type="Rhea" id="RHEA-COMP:9714"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:78499"/>
            <dbReference type="ChEBI" id="CHEBI:78501"/>
            <dbReference type="EC" id="1.2.1.103"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-lysine biosynthesis via AAA pathway; L-lysine from L-alpha-aminoadipate (Thermus route): step 3/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.1.103" evidence="1"/>
    <dbReference type="EMBL" id="LGCL01000018">
        <property type="protein sequence ID" value="KPL78408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062205.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000018.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06690"/>
    <dbReference type="EnsemblBacteria" id="KPL78408">
        <property type="protein sequence ID" value="KPL78408"/>
        <property type="gene ID" value="ADN00_06690"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00033">
        <property type="reaction ID" value="UER00037"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043870">
        <property type="term" value="F:N-acetyl-gamma-aminoadipyl-phosphate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003942">
        <property type="term" value="F:N-acetyl-gamma-glutamyl-phosphate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006526">
        <property type="term" value="P:arginine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019878">
        <property type="term" value="P:lysine biosynthetic process via aminoadipic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00150">
        <property type="entry name" value="ArgC_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02083">
        <property type="entry name" value="LysY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000706">
        <property type="entry name" value="AGPR_type-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037535">
        <property type="entry name" value="LysY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000534">
        <property type="entry name" value="Semialdehyde_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01118">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00859">
        <property type="entry name" value="Semialdhyde_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01850">
        <property type="entry name" value="argC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Semialdhyde_dh" evidence="2">
        <location>
            <begin position="3"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="active site" evidence="1">
        <location>
            <position position="147"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="10"/>
            <end position="13"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <begin position="34"/>
            <end position="36"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="311"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="344" mass="37585" checksum="AEA6D13D784DD291" modified="2016-01-20" version="1">MIQATIIGGTGYTGGELLRILAFHPQVEVTQVTSRRSMGEYVYQTHPNLRKVSQLKFISPDVLEPTPVCFLALPHGEAQHKIEELAQKFEYIIDLSADFRLKAPAAYQKWYGEPHAAPEWLPKFTYGLPELHREELKSARYVSGVGCNATACNLSMYPLLQAGLIDTSLPVIFEIKVGSSEGGASENPGSHHPERSSVIRTYAPYGHRHTAEVIQELGLSKVSLTMTSVDLVRGALATGHATVKAGVEAKDLWKAYREAAASNPFLRVVKERRGVYRVPEPKILAGSNYADLGFDLDPESGHVITICAIDNLMKGASGTAVQCMNLMLGFDETLGLSFPGLHPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5W8</accession>
    <name>A0A0P6X5W8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF3343 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_06800</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000018">
        <property type="protein sequence ID" value="KPL78427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062227.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000018.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06800"/>
    <dbReference type="EnsemblBacteria" id="KPL78427">
        <property type="protein sequence ID" value="KPL78427"/>
        <property type="gene ID" value="ADN00_06800"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021778">
        <property type="entry name" value="Se/S_carrier-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11823">
        <property type="entry name" value="DUF3343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF3343" evidence="1">
        <location>
            <begin position="4"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF11823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="75" mass="8345" checksum="C2D4E3E9420A97DB" modified="2016-01-20" version="1">MTEYAYFLVDSTAQAMRLEKILMDKGVECKLVPVPRQFSSDCGLCARVPKSLLEPAVKLLAAAKAAYREIVFDYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7X3</accession>
    <name>A0A0P6X7X3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_12790</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063411.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000027.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL75518">
        <property type="protein sequence ID" value="KPL75518"/>
        <property type="gene ID" value="ADN00_12790"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL75518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="68" mass="7766" checksum="B2934B49DABB1A8E" modified="2016-01-20" version="1">MKKPDEQSSPEFKGKKEDQTEKPVFHVFDRGMSDDEFVDAIEKIVYRMKEEKRKKEDAGKSDGVGAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X810</accession>
    <name>A0A0P6X810_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fe/B12 periplasmic-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_04660</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79149.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061792.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04660"/>
    <dbReference type="EnsemblBacteria" id="KPL79149">
        <property type="protein sequence ID" value="KPL79149"/>
        <property type="gene ID" value="ADN00_04660"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002491">
        <property type="entry name" value="ABC_transptr_periplasmic_BD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01497">
        <property type="entry name" value="Peripla_BP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50983">
        <property type="entry name" value="FE_B12_PBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132893" description="Fe/B12 periplasmic-binding domain-containing protein" evidence="1">
        <location>
            <begin position="25"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="Fe/B12 periplasmic-binding" evidence="2">
        <location>
            <begin position="53"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79149.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="309" mass="32734" checksum="59853EC9BBBCA1F3" modified="2016-01-20" version="1">MKRRFVPVLLFTLLSLLLASCAPIAPTSPTAVQPIILTDALGREVSLAQPAQKIVSTAPSNSEILFAIGAGAQVIARDDFTNYPPEALDLPSVGGMSGFNLEAITALQPDLVLVAEINTAEDVKALEDLGLTVYMVPNPTDLEGLYTNLVNVGKMTGREAEAAALAEELKARVEAVTQAVASVETRPSVFYELDGSDPAKPWTSGPGTFIDLLINMAGGQNAVTVDSPWVQLSLEELIVTDPDFILLGDSTWGGVTPEMVAERAGWNALSAVQNGKVLPFNDDLVGRPGPRLVDGLEELAKILHPDLVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X888</accession>
    <name>A0A0P6X888_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Cell division protein FtsZ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">ftsZ</name>
        <name evidence="9" type="ORF">ADN00_07420</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">Essential cell division protein that forms a contractile ring structure (Z ring) at the future cell division site. The regulation of the ring assembly controls the timing and the location of cell division. One of the functions of the FtsZ ring is to recruit other cell division proteins to the septum to produce a new cell wall between the dividing cells. Binds GTP and shows GTPase activity.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer. Polymerizes to form a dynamic ring structure in a strictly GTP-dependent manner. Interacts directly with several other division proteins.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="4">Assembles at midcell at the inner surface of the cytoplasmic membrane.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the FtsZ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062348.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07420"/>
    <dbReference type="EnsemblBacteria" id="KPL78286">
        <property type="protein sequence ID" value="KPL78286"/>
        <property type="gene ID" value="ADN00_07420"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3307"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032153">
        <property type="term" value="C:cell division site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000917">
        <property type="term" value="P:division septum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043093">
        <property type="term" value="P:FtsZ-dependent cytokinesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051258">
        <property type="term" value="P:protein polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02201">
        <property type="entry name" value="FtsZ_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00909">
        <property type="entry name" value="FtsZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000158">
        <property type="entry name" value="Cell_div_FtsZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020805">
        <property type="entry name" value="Cell_div_FtsZ_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045061">
        <property type="entry name" value="FtsZ/CetZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024757">
        <property type="entry name" value="FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037103">
        <property type="entry name" value="Tubulin/FtsZ-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018316">
        <property type="entry name" value="Tubulin/FtsZ_2-layer-sand-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30314">
        <property type="entry name" value="PTHR30314"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12327">
        <property type="entry name" value="FtsZ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00423">
        <property type="entry name" value="CELLDVISFTSZ"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00865">
        <property type="entry name" value="Tubulin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="SSF52490"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="SSF55307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00065">
        <property type="entry name" value="ftsZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01134">
        <property type="entry name" value="FTSZ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01135">
        <property type="entry name" value="FTSZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="4 5 9" id="KW-0132">Cell division</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2 4 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0717">Septation</keyword>
    <feature type="domain" description="Tubulin" evidence="7">
        <location>
            <begin position="14"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="Tubulin_C" evidence="8">
        <location>
            <begin position="208"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="320"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="22"/>
            <end position="26"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="109"/>
            <end position="111"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="140"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="144"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL78286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="382" mass="40338" checksum="6CA46517337FA821" modified="2016-01-20" version="1">MEQLNQSFSESFARIKVVGVGGGGCNAVNRMIAEGLQGIEFIAVNTDAQALLMSQAKTRVRIGDKVTRGLGAGGNPDNGKKAAEESADELYEVLKGSDMVFITAGLGGGTGTGAAPIIAQISKEIGALTIGVVTRPFTFEGSKRQTSAENGIANLKEKADTLIVIPNDRLLQIVDKRASLNEAFHVADDVLRQGIQGISELITVPGLINLDFADVRTIMSEGGAALMAVGKASGEDRARVAAEMAISSQLLDITIDGARGILFNVTGGEGLTLFEVNTAAAIIKETAHPDVNLIFGAVVDPTMGDEIRVTVIATGFDHTGGVRPISTPRTMRTEQSAPRRPTMQDHVDPIDQRSPAPAEFAPRVLNTENLDIPAFLRNRNGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X8G4</accession>
    <name>A0A0P6X8G4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 10">1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase</fullName>
            <ecNumber evidence="8 10">5.3.1.16</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8">Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="primary">hisA</name>
        <name evidence="11" type="ORF">ADN00_17455</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 8 10">
            <text>1-(5-phospho-beta-D-ribosyl)-5-[(5-phospho-beta-D-ribosylamino)methylideneamino]imidazole-4-carboxamide = 5-[(5-phospho-1-deoxy-D-ribulos-1-ylimino)methylamino]-1-(5-phospho-beta-D-ribosyl)imidazole-4-carboxamide</text>
            <dbReference type="Rhea" id="RHEA:15469"/>
            <dbReference type="ChEBI" id="CHEBI:58435"/>
            <dbReference type="ChEBI" id="CHEBI:58525"/>
            <dbReference type="EC" id="5.3.1.16"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 8 10">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 4/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 8 10">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 8 9">Belongs to the HisA/HisF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.16" evidence="8 10"/>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71467.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064330.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17455"/>
    <dbReference type="EnsemblBacteria" id="KPL71467">
        <property type="protein sequence ID" value="KPL71467"/>
        <property type="gene ID" value="ADN00_17455"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.559"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00009"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003949">
        <property type="term" value="F:1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino]imidazole-4-carboxamide isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04732">
        <property type="entry name" value="HisA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01014">
        <property type="entry name" value="HisA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006062">
        <property type="entry name" value="His_biosynth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006063">
        <property type="entry name" value="HisA_bact_arch"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044524">
        <property type="entry name" value="Isoase_HisA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023016">
        <property type="entry name" value="Isoase_HisA-like_bact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43090">
        <property type="entry name" value="PTHR43090"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00977">
        <property type="entry name" value="His_biosynth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00007">
        <property type="entry name" value="TIGR00007"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8 9" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8 10" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 8 9" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="7 8 10" id="KW-0413">Isomerase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="8">
        <location>
            <position position="12"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="8">
        <location>
            <position position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005133"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL71467.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="246" mass="26633" checksum="803063DBFD64ED2D" modified="2016-01-20" version="1">MNSSFVIFPAIDLRAGQVVRLKEGDPARQTHYSADPAQTAQKWLDAGARWLHVINLDGAFEEPDNANRRAVEQIVQTARRCQAKVQLGGGLRDLTSAQEALELGVARVIFGTLAVRQPQTIAEAVRRWGAERVAVSLDARGGVIQVRGWQETSGLLVEDFALQLKAIGLEWLVFTDIARDGLQTGINLRATAQLAQKTGLKVIASGGVHQMEDVRSARSAGLAGCIVGRALYEGSIDPLELFQGEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X8I5</accession>
    <name>A0A0P6X8I5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_17355</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17355"/>
    <dbReference type="EnsemblBacteria" id="KPL71494">
        <property type="protein sequence ID" value="KPL71494"/>
        <property type="gene ID" value="ADN00_17355"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00038">
        <property type="entry name" value="CAP_ED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018490">
        <property type="entry name" value="cNMP-bd-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000595">
        <property type="entry name" value="cNMP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00027">
        <property type="entry name" value="cNMP_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00100">
        <property type="entry name" value="cNMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51206">
        <property type="entry name" value="SSF51206"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50042">
        <property type="entry name" value="CNMP_BINDING_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="2"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclic nucleotide-binding" evidence="4">
        <location>
            <begin position="224"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="35"/>
            <end position="42"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL71494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="354" mass="38554" checksum="D25B0469F57B94EA" modified="2016-01-20" version="1">MRNVVKTFKTPAGQFSALKNVSLGFTTGDFAAITGKSGSGKSTLINMITGIDVPSSGEVCVGGVPVHQLSESQMAIWRGRNLGIVFQFFQLLPTLSLLENTMLPMDIAGVIDISEREKRAMRLLKMVGLESVVHKMPAAVSIGQQQAAAIARALANDPPFLVADEPTGNLDSRTAENVFEIFEHLSSQGKTILMITHDPALAQRTARQVLLSDGEIVNPWIHKTFPMLNHAQMLSATHQLESLTYRAGEPIIQQGEPSDALYILTEGRVDVSIQGQVVARLSPGDFFGEMELLEENRAVATVRAASDEKVETVSLGRGFFSTLMDEARALRDMLTKVVRERTAQNLALLGSRIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X938</accession>
    <name>A0A0P6X938_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Deacetylase sirtuin-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_12240</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76103.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063301.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12240"/>
    <dbReference type="EnsemblBacteria" id="KPL76103">
        <property type="protein sequence ID" value="KPL76103"/>
        <property type="gene ID" value="ADN00_12240"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3924"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070403">
        <property type="term" value="F:NAD+ binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029035">
        <property type="entry name" value="DHS-like_NAD/FAD-binding_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003000">
        <property type="entry name" value="Sirtuin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026591">
        <property type="entry name" value="Sirtuin_cat_small_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026590">
        <property type="entry name" value="Ssirtuin_cat_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02146">
        <property type="entry name" value="SIR2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52467">
        <property type="entry name" value="SSF52467"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50305">
        <property type="entry name" value="SIRTUIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Deacetylase sirtuin-type" evidence="3">
        <location>
            <begin position="11"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50305"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL76103.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="254" mass="28381" checksum="01E47A44F347D5A2" modified="2016-01-20" version="1">MISHSPDQAIAQAASLLKQARHAVVLTGAGISTPSEIPDFRSAGSGLWTKNDPMRVASLTTFHRRPQDFFDWLQPLARQAYYARPNPAHLGLARLEQAGLVKAVITQNIDDLHHKASSQNIIEVHGSMRTFECLRCQVSYPLEDFVTTFIERAEPPRCAHCNSFLKPAITLYEEMLPAEAWNNAQWHCEHCDLILVIGSSLETVPAAHLPVFALENNAHLLINTFSPTPLDLEAELVFRQDVVEFISQLVQQVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-04-07" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XA24</accession>
    <name>A0A0P6XA24_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Response regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_17185</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064282.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL71424">
        <property type="protein sequence ID" value="KPL71424"/>
        <property type="gene ID" value="ADN00_17185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="8"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL71424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="134" mass="15139" checksum="CA274BCE7063BC50" modified="2016-01-20" version="1">MNAETKLPVLLVEANPTQSALLKLALNRIENLQVHHLAEGEEVIPFIQKNRPLMVIIDLFLPGVNGLHLVEQVKKLEIPRRPRIMVLSSLGYPVVVRQIAQIGVDDFLVKPVNTDVFVERVRKIIKEQVIGRSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XA34</accession>
    <name>A0A0P6XA34_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HDOD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_17305</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064304.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17305"/>
    <dbReference type="EnsemblBacteria" id="KPL71443">
        <property type="protein sequence ID" value="KPL71443"/>
        <property type="gene ID" value="ADN00_17305"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013976">
        <property type="entry name" value="HDOD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08668">
        <property type="entry name" value="HDOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51833">
        <property type="entry name" value="HDOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HDOD" evidence="1">
        <location>
            <begin position="15"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL71443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="281" mass="30549" checksum="59AFEF157F910ED1" modified="2016-01-20" version="1">MNLTINTLLDRIGELPPMQEAAQKALIMIRHPDTNMRALAEVLSTDQILASLVLRWANSAYYGLSAPVKTVQQAVVVLGKNTIQSLLFAATLANLLNRPAPGYALDRGALWKHSIGVAAGARLIAARYNPALMEEAYHAGLLCDVGKLALEFYLRDVQFDREKIKNMSFIEIETGLLGMDHAVIGKELAHRWNLPVSLQNAIAFHHRPSQAGDAFILASAVHLADAATMLLGIGIGSDGLQYPLDEAALVRLNWSEDSFTELFEKIPAAVSAAVDLIGMMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XA65</accession>
    <name>A0A0P6XA65_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_17095</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17095"/>
    <dbReference type="EnsemblBacteria" id="KPL71488">
        <property type="protein sequence ID" value="KPL71488"/>
        <property type="gene ID" value="ADN00_17095"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013367">
        <property type="entry name" value="Flagellar_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12611">
        <property type="entry name" value="Flagellar_put"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02530">
        <property type="entry name" value="flg_new"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL71488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="140" mass="15321" checksum="CC46F7DC1498C101" modified="2016-01-20" version="1">MRIQNGQSVYGPQNASKASSSPEEGQISFAETLARVQQGVQFTNHAQKRLEKRNIALNDDGIARLAQAVDKAEKRGGKESLVLMDDIAFLVNVKERLVITAVDQDHRGEGVFTQIDSVVFADPSEQINPDNQGTSKEIKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAZ0</accession>
    <name>A0A0P6XAZ0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Voltage-gated potassium channel</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_03035</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the shaker potassium channel beta subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000014">
        <property type="protein sequence ID" value="KPL79319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061485.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000014.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03035"/>
    <dbReference type="EnsemblBacteria" id="KPL79319">
        <property type="protein sequence ID" value="KPL79319"/>
        <property type="gene ID" value="ADN00_03035"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005399">
        <property type="entry name" value="K_chnl_volt-dep_bsu_KCNAB-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43150">
        <property type="entry name" value="PTHR43150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01577">
        <property type="entry name" value="KCNABCHANNEL"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0407">Ion channel</keyword>
    <keyword evidence="3" id="KW-0406">Ion transport</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="2">
        <location>
            <begin position="15"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="320" mass="36004" checksum="4FDBFDAE5F4125F3" modified="2016-01-20" version="1">MHYRRLGRSGLKVSEISLGAWITFGKQIETNTAADLIHAAYDQGVNFFDNADVYADGQAETVMGKAIEGLPREALVISSKVFWPTMPGPNGRGLSRKHMTESLHASLKRLGTDYVDLYFCHRFDPDTGVEEVVRTMNIFIQQGKILYWGTSEWEAQQVMEAIGVARQYGLIPPVVEQPQYNMFHRKLVEAELMSVTQQQGIGLVTWSPLFYGILTGKYNDGIPAGSRASLDDMNWIRDYITQERIEKVRALTELARELEVTTAQLAIGWLLRRKEVTSVITGATRLEQLDDNLAAPAALDKMSLEVLERIEEILDNNPVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBY4</accession>
    <name>A0A0P6XBY4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_09215</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77301.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77301">
        <property type="protein sequence ID" value="KPL77301"/>
        <property type="gene ID" value="ADN00_09215"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL77301.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="62" mass="6887" checksum="A026090178DB41E3" modified="2016-01-20" version="1">MRKAAHKSNKRPELQAVLGYYVETGPLGKFPSAHRDEIDRLVGGKKAAFLSMSAMNKKKGDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XC06</accession>
    <name>A0A0P6XC06_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_02130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000009">
        <property type="protein sequence ID" value="KPL79785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79785">
        <property type="protein sequence ID" value="KPL79785"/>
        <property type="gene ID" value="ADN00_02130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="13"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="47"/>
            <end position="66"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="69" mass="7425" checksum="37B680ED5FC97032" modified="2016-01-20" version="1">MFHLWKGGGPGKLLLYILLGWVGFWAGVILGTMMGLVFWTIGPLNVGMGLIGSLLFLGGGYWLSLIQAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XCB4</accession>
    <name>A0A0P6XCB4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MFS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_01395</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80529.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061173.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80529">
        <property type="protein sequence ID" value="KPL80529"/>
        <property type="gene ID" value="ADN00_01395"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="90"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="114"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="148"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="177"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="221"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="259"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="292"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="317"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="351"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="376"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="25"/>
            <end position="398"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL80529.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="413" mass="43668" checksum="A881590CBEE7078A" modified="2016-01-20" version="1">MSHSPFDPVSASSITARRPVSLAGQVTLFGLSRFVFNISLRMVYPFLAFFARGLGVDLYAISSVITYRSLGGILTPFITPIADRYGRKTGMLLGVGLFVLGSLAILIWPVYPVFVLTLCLHSLGVFIFAPSIQAYISDHVPYFQRGRVLALVEISWAASFFAGIPLVGLLFETYGWFAVFPILAVLSIIVFVVVLSVVPADAPDGARGQAASLLDGARQIVASKAAVAALLMGLLYNIANDVFGVVFGVWLEDSFGLKIAALGAASAVIGIAELGGESLTAGWVDRIGKQRAIFIGLTANCLVSLALPFLGRSLPGALVGLFLFYISYEITVVSSMPIVTEIVPGARATMLGLNVAALSAGRGVGAFLSARLFTSFGIWANLLAALLFDVLAIAALSQIRMDAHGQQTGEKPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDG3</accession>
    <name>A0A0P6XDG3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Purine nucleoside phosphorylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ADN00_00065</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>adenosine + H(+) + H2O = inosine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:24408"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16335"/>
            <dbReference type="ChEBI" id="CHEBI:17596"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.4"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="4">
            <dbReference type="Rhea" id="RHEA:24409"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>adenosine + phosphate = adenine + alpha-D-ribose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:27642"/>
            <dbReference type="ChEBI" id="CHEBI:16335"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57720"/>
            <dbReference type="EC" id="2.4.2.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="2">
            <dbReference type="Rhea" id="RHEA:27643"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>inosine + phosphate = alpha-D-ribose 1-phosphate + hypoxanthine</text>
            <dbReference type="Rhea" id="RHEA:27646"/>
            <dbReference type="ChEBI" id="CHEBI:17368"/>
            <dbReference type="ChEBI" id="CHEBI:17596"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57720"/>
            <dbReference type="EC" id="2.4.2.1"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="1">
            <dbReference type="Rhea" id="RHEA:27647"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>phosphate + S-methyl-5'-thioadenosine = adenine + S-methyl-5-thio-alpha-D-ribose 1-phosphate</text>
            <dbReference type="Rhea" id="RHEA:11852"/>
            <dbReference type="ChEBI" id="CHEBI:16708"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58533"/>
            <dbReference type="EC" id="2.4.2.28"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="3">
            <dbReference type="Rhea" id="RHEA:11853"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="5 9">Belongs to the purine nucleoside phosphorylase YfiH/LACC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL80987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060917.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00065"/>
    <dbReference type="EnsemblBacteria" id="KPL80987">
        <property type="protein sequence ID" value="KPL80987"/>
        <property type="gene ID" value="ADN00_00065"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3409"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004000">
        <property type="term" value="F:adenosine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017061">
        <property type="term" value="F:S-methyl-5-thioadenosine phosphorylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd16833">
        <property type="entry name" value="YfiH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.140.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003730">
        <property type="entry name" value="Cu_polyphenol_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038371">
        <property type="entry name" value="Cu_polyphenol_OxRdtase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011324">
        <property type="entry name" value="Cytotoxic_necrot_fac-like_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30616">
        <property type="entry name" value="PTHR30616"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02578">
        <property type="entry name" value="Cu-oxidase_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64438">
        <property type="entry name" value="SSF64438"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00726">
        <property type="entry name" value="TIGR00726"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001229"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00001600"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00007353"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU361274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL80987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="265" mass="29357" checksum="A903F07DFC8CD452" modified="2016-01-20" version="1">MTLKQAENLEFFQFDLFAGANLTHGLFTRKGGISPAPWHSLNLGGTTGDRRENVIENRRRIFDCVGRPVESIFDTWQVHGVHVIFPEAPRPLDGVHEKADIIITDRPELTLFMRFADCVPIMLYDPRKNVIGLVHAGWQGTVKLAARVAVEAMAQRYGCQPGDILAGIGPSIGPDDYEVGEDVAERFRHAFGEQAGRLIRCENGKMYLNLWEANSIVLRACGVHEIEVAGISTASDTTRWYSHRAENGATGRYGALIALGEVWGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDQ7</accession>
    <name>A0A0P6XDQ7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Lipoprotein signal peptidase</fullName>
            <ecNumber evidence="6">3.4.23.36</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Prolipoprotein signal peptidase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Signal peptidase II</fullName>
            <shortName evidence="6">SPase II</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">lspA</name>
        <name evidence="9" type="ORF">ADN00_07120</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">This protein specifically catalyzes the removal of signal peptides from prolipoproteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>Release of signal peptides from bacterial membrane prolipoproteins. Hydrolyzes -Xaa-Yaa-Zaa-|-(S,diacylglyceryl)Cys-, in which Xaa is hydrophobic (preferably Leu), and Yaa (Ala or Ser) and Zaa (Gly or Ala) have small, neutral side chains.</text>
            <dbReference type="EC" id="3.4.23.36"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="6">Protein modification; lipoprotein biosynthesis (signal peptide cleavage).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cell membrane</location>
            <topology evidence="6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the peptidase A8 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.23.36" evidence="6"/>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78349.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07120"/>
    <dbReference type="EnsemblBacteria" id="KPL78349">
        <property type="protein sequence ID" value="KPL78349"/>
        <property type="gene ID" value="ADN00_07120"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3242"/>
    <dbReference type="UniPathway" id="UPA00665"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004190">
        <property type="term" value="F:aspartic-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00161">
        <property type="entry name" value="LspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001872">
        <property type="entry name" value="Peptidase_A8"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33695">
        <property type="entry name" value="PTHR33695"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01252">
        <property type="entry name" value="Peptidase_A8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00781">
        <property type="entry name" value="LIPOSIGPTASE"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00077">
        <property type="entry name" value="lspA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 6" id="KW-0064">Aspartyl protease</keyword>
    <keyword evidence="2 6" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="59"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="90"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="128"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="156"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="118"/>
        </location>
    </feature>
    <feature type="active site" evidence="6">
        <location>
            <position position="132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006139"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL78349.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="179" mass="19596" checksum="A4411070B3B51B3E" modified="2016-01-20" version="1">MRDYLVLLLISGSVIGLDQWTKSLVRASLELGEMWSPWPWLTPYARIVHWYNTGSAFGMFQGLGMVFTVLAFVIAGAIIFYYPRVPREEWGLRLALGLQLGGAMGNLIDRLTIGHVTDFVSVGTFPVFNVADSSITVGVGVLLLSMYLQERAAQKQSAGQVKQEDPADAAVQGDASIEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDW2</accession>
    <name>A0A0P6XDW2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Aminotransferase</fullName>
            <ecNumber evidence="1">2.6.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_00945</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the class-I pyridoxal-phosphate-dependent aminotransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.-" evidence="1"/>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061074.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00945"/>
    <dbReference type="EnsemblBacteria" id="KPL81120">
        <property type="protein sequence ID" value="KPL81120"/>
        <property type="gene ID" value="ADN00_00945"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3587"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004838">
        <property type="entry name" value="NHTrfase_class1_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00105">
        <property type="entry name" value="AA_TRANSFER_CLASS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="2">
        <location>
            <begin position="45"/>
            <end position="395"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU000481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL81120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="403" mass="44707" checksum="507D871538554888" modified="2016-01-20" version="1">MKPSNSSNTHPVNFEPAQRIAGFKPYYFATLNRRIDQLRSQGKDIIRIDIGSPDLPPADFIIETLVESAKSTEHHGYGPNGGPAKFKQAVAEYYHHRFNVELDPSSQVLGLIGSKEGLFHLTQVLINPGDIVLVPDPGYPVYKASALIAGAEVVTLPLLAENGFLPDLDSIPSEIAQRSKILWLNYPNNPTGAVADLAFFQKAVDFGRRNNCMIAHDAPYTDVCFNEYVAPSILEVDGAEEVCVEFNSLSKTYNMAGWRIGMAVGNPKVISYMHTYKSQLDTSQFTPIFDAGVAALTHDQKWLVERNHIYQQRRDIILEGIRSVGFTALTPPAAIYVWARLPEKFSNSMDFCNRALEEIGLSITPGVIYGEHGEGFVRLSLCTPADRLQQAMSRLSGWMKTQN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XEZ6</accession>
    <name>A0A0P6XEZ6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NMT1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_05860</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78760.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062035.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05860"/>
    <dbReference type="EnsemblBacteria" id="KPL78760">
        <property type="protein sequence ID" value="KPL78760"/>
        <property type="gene ID" value="ADN00_05860"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1648"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009228">
        <property type="term" value="P:thiamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027939">
        <property type="entry name" value="NMT1/THI5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015168">
        <property type="entry name" value="SsuA/THI5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31528">
        <property type="entry name" value="PTHR31528"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09084">
        <property type="entry name" value="NMT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133017" description="NMT1 domain-containing protein" evidence="1">
        <location>
            <begin position="25"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="domain" description="NMT1" evidence="2">
        <location>
            <begin position="53"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78760.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="334" mass="36871" checksum="E792229C6600E176" modified="2016-01-20" version="1">MKKSVYTIFSILILASILLTGCQAAPVAESQEAAPAELEKVTIVADWPTPWVGFIPWLVAQEKGFYAEEGLTVETILPATVADPPKYVALGKADFAYTTQLDVILGRAAGIPIVSTAAVFRYNNWGIIYPKDGNVKELKDIKTLSLYENTWDHACFNAMMAHEGLDVSTVNILPSTSDTVPLFLAGKVDAVGGITNAEQTEVLITGGEETNIFMGRDYGVPDVYVYVFASSNQFLTEHPETAEKFMRATLKGLQYSVDNPEEALDIFMKIYPEALSEEYAKASWEATVPVFKTDKYGYQVPALWTEVQDFMLEIGLIEETAPVEELFTNQFIAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XFP9</accession>
    <name>A0A0P6XFP9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_03705</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061617.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79007">
        <property type="protein sequence ID" value="KPL79007"/>
        <property type="gene ID" value="ADN00_03705"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="125"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="320" mass="34380" checksum="E4B76FC5F44231DC" modified="2016-01-20" version="1">MTNTGNSTGSPRSINAKLDQLEGAIGSLSFGTDEQALEILEGMDEINALLAHGQQAGDQLDAEWVQWDYICQQVKKNANLLVKKIGGPAGLMKRRSELQADETAWWWNLDEYLAHKRKAAWRKTLIGLGGGLLLLALLAGAYQLFLAPPPEVAASYRHRTSAESAMQNGDLTAALAEIDLALSYTPDDYELLTIRSVLLEKNGDLQSAEEALAQARALAPAEVNVLMAQGQTSLYLQDAAGMRAAGERLEEGYPASPYGPIFLGSAAELEGDYPSALQYLQEAAARAEAQGDANLSGNLRVRVAMLTQKSLAPVDPTLTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XFV8</accession>
    <name>A0A0P6XFV8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">D-ser_dehydrat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_04125</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DSD1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061694.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04125"/>
    <dbReference type="EnsemblBacteria" id="KPL79071">
        <property type="protein sequence ID" value="KPL79071"/>
        <property type="gene ID" value="ADN00_04125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026956">
        <property type="entry name" value="D-ser_dehydrat-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042208">
        <property type="entry name" value="D-ser_dehydrat-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14031">
        <property type="entry name" value="D-ser_dehydrat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01119">
        <property type="entry name" value="D-ser_dehydrat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-ser_dehydrat" evidence="2">
        <location>
            <begin position="253"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="370" mass="40856" checksum="CB28102080A8FD9A" modified="2016-01-20" version="1">MPDIFPTIKRPTLLLDEKTARRNLHSMALRARQAGARFRPHFKTHQSAAIGEWFRDLEINAITVSSVDMAQYFARAGWQDILIAFPFNWREIDEVNQLASQIHLGLLVESRDTARFLNWHLNHPVDVWIKIDVGSQRTGLAWDDPEAVQALAADLQRGRQLRLRGLLTHAGHSYRARGAEEVCALHQQSMQRLTGLRDQLTQAGLPALEISIGDTPSCSLCDCTGADELRPGNFLFYDVQQSQIGSCQPADIAVAVACPVVALHPERNEAVVFGGAIHLSKDAFDLDGRPAYGLVCLPQPNGWGAPLPGAFVRGLSQEHGVLHLPEEDLARVRVGDLLCILPAHSCLTVTLMRSYLTLTGQVVPTMHSPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XFY6</accession>
    <name>A0A0P6XFY6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">DNA helicase</fullName>
            <ecNumber evidence="3">3.6.4.12</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_14290</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + H2O = ADP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.12"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the helicase family. UvrD subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.12" evidence="3"/>
    <dbReference type="EMBL" id="LGCL01000034">
        <property type="protein sequence ID" value="KPL73737.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063708.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000034.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14290"/>
    <dbReference type="EnsemblBacteria" id="KPL73737">
        <property type="protein sequence ID" value="KPL73737"/>
        <property type="gene ID" value="ADN00_14290"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003678">
        <property type="term" value="F:DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013986">
        <property type="entry name" value="DExx_box_DNA_helicase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000212">
        <property type="entry name" value="DNA_helicase_UvrD/REP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014016">
        <property type="entry name" value="UvrD-like_ATP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11070">
        <property type="entry name" value="PTHR11070"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51198">
        <property type="entry name" value="UVRD_HELICASE_ATP_BIND"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UvrD-like helicase ATP-binding" evidence="7">
        <location>
            <begin position="211"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="232"/>
            <end position="239"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00560"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL73737.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="672" mass="76882" checksum="85CF2E85CF5BC00C" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGC3</accession>
    <name>A0A0P6XGC3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH gntR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05760</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062016.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05760"/>
    <dbReference type="EnsemblBacteria" id="KPL78745">
        <property type="protein sequence ID" value="KPL78745"/>
        <property type="gene ID" value="ADN00_05760"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1628"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1410.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028978">
        <property type="entry name" value="Chorismate_lyase_/UTRA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011663">
        <property type="entry name" value="UTRA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07702">
        <property type="entry name" value="UTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00866">
        <property type="entry name" value="UTRA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64288">
        <property type="entry name" value="SSF64288"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="1">
        <location>
            <begin position="12"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="249" mass="28031" checksum="64AE122A8B8B8D0B" modified="2016-01-20" version="1">MELNTLDKGSHTPLYLQLARQLIRQIQSGVLKPGDKIPSERELSESLNVSRITSRQAIESLLKSGLIYREQGRGTFVAESKMHGIQGFSSFTEDIRSRGYQPGSKVIKQELVPVDEKCRQKLKMGPDELVLHLVRLRLADGEPIAIQYTHLPSRICPGLENEDLENRSLFSVLRDRYFIHPAWTEAEVRASNPTPEEADLLGIGLDEPVLVVDGVTFTESFDMVEVVRTVYNGKSISLYMGRQRLGLLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGL0</accession>
    <name>A0A0P6XGL0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Sugar ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_05630</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062166.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05630"/>
    <dbReference type="EnsemblBacteria" id="KPL78873">
        <property type="protein sequence ID" value="KPL78873"/>
        <property type="gene ID" value="ADN00_05630"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1603"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="113"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="187"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="239"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="296"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL78873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="354" mass="37429" checksum="A7489F9CCC7EF78E" modified="2016-01-20" version="1">MDSVLVKKSRGITKTDIQQFLLRGRAFIALILVLVVFTLLSPQFLSGDNIVIMSKHVAINALLATGMTFIILTGGIDLSVGSIVGMTAMIAGGLINEGLRIPQLGIIVYPHTWTIILISLAVGTLMGAISGLIITRFNVAPFIATLGTMYVARGIAGLRNNGYTFPNLVGRPEYGNTGFELLGSGNFLGINYSIWMMIIFAVVAYIVTTRLPFGRHVYSIGGNERAAELSGVRINRTKVIVYSISGFCSAMVGLIIASQLVAAHPATGEAFEMNAIAAVVLGGTSLAGGRGSIGGSLIGAFVIGVLGDGLVMMGVSSFWQKVIKGAVIVLAVIIDQAQARMQERIALQKQQELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XH67</accession>
    <name>A0A0P6XH67_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">3-oxoadipate:succinyl-CoA transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_04595</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061780.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04595"/>
    <dbReference type="EnsemblBacteria" id="KPL79139">
        <property type="protein sequence ID" value="KPL79139"/>
        <property type="gene ID" value="ADN00_04595"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.280"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008410">
        <property type="term" value="F:CoA-transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004165">
        <property type="entry name" value="CoA_trans_fam_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01144">
        <property type="entry name" value="CoA_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00882">
        <property type="entry name" value="CoA_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="300" mass="33708" checksum="2DC586BE40588081" modified="2016-01-20" version="1">MNKLCSLQEAIQQWVHDRDCLYAAGFTHLIPFAAGHEIIRQGRRDLCLARATPDLIYEQMVAAGCAKKLIFSYSGNPGVGSLHMVREELEKGSLEWEEYSHFGMITRLQAGAAGLPFMPMNQTAAGDLERANPQYRRVKDPYSDGEVVVLPALRPDVAIVHVQRADARGNAQIWGIIGEQKEAAFAAQHVIITAEEIVDEAVIRSDPNRTLIPDFIVDAVCHVPYCAHPSYTQGYYDRDNEFYLAWDKISETRQGIEAYLDEWVYGTRDRADYVTKLGTATLERLKVAPRWSAPVNYGAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XH92</accession>
    <name>A0A0P6XH92_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13230</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74804.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063496.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000031.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13230"/>
    <dbReference type="EnsemblBacteria" id="KPL74804">
        <property type="protein sequence ID" value="KPL74804"/>
        <property type="gene ID" value="ADN00_13230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133058" evidence="1">
        <location>
            <begin position="21"/>
            <end position="224"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74804.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="224" mass="24276" checksum="0A60A444A58AA32B" modified="2016-01-20" version="1">MKAKRKILIALSILILTALACGLPNFGSNDEPGQSSVVEQGPTVLYQDDFSSTSSGWDVYSDADMTTDYFDGGYHILVTATQYYSWANPGKTFTDTHTEVNAKFLAGAQDAELGLICRYQDNSNFYFGIVGADGYYGIFKTLDGEFNLIGMDSMSTSPKINQGLSSNKVRLDCVGDTLTLYANGEILAQVKDSQFTSGDVGLIAGTYDVAGTDAWFDDLVVYQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XIG0</accession>
    <name>A0A0P6XIG0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_02420</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000010">
        <property type="protein sequence ID" value="KPL79669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061364.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000010.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79669">
        <property type="protein sequence ID" value="KPL79669"/>
        <property type="gene ID" value="ADN00_02420"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="112"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="316" mass="35925" checksum="E8D9C02991D6DFD2" modified="2016-01-20" version="1">MSAMEFHPPVFPFSSNLCVMCGQPATEKLDFDASQEATRYFLVGRVETAKFGSVYQVPYCQTHWQMAQRMMKRIKRYSITNDIASLLLLISSIFLSFSLFRNYGEKDLIGSIILKVLGGILIGGFLLFPFEPLFRLINGMFMPIGMRKEEIEDLRQHLKAQGPGMPYTGSVSYLPGISVNYFIPEGMTVPTAKTIYVTSPEFAQETNLRTVGQVLLERANRDKTIKKRAVAKGNLVKYCSILQEKVELKKLPEYDTLVCDQSIQGSGNIAVCDQLCKRNIKQVMMLETVFKTKQLNETQRKNMETFLGLRDCTEER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XJX6</accession>
    <name>A0A0P6XJX6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DEDD_Tnp_IS110 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01785</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000005">
        <property type="protein sequence ID" value="KPL80473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80473">
        <property type="protein sequence ID" value="KPL80473"/>
        <property type="gene ID" value="ADN00_01785"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004803">
        <property type="term" value="F:transposase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006313">
        <property type="term" value="P:transposition, DNA-mediated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002525">
        <property type="entry name" value="Transposase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01548">
        <property type="entry name" value="DEDD_Tnp_IS110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEDD_Tnp_IS110" evidence="1">
        <location>
            <begin position="5"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01548"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="125" mass="13848" checksum="BC601D8DB21E7FCD" modified="2016-01-20" version="1" fragment="single">MTFYCGIDVAKRKHAVAILNESGQVCKPVFVTENTRAGLAYLLEHLSQLGNEVSVGLEATGHYWLSLYDVLTSQGYPVSVINPLQISAYRKSGVRKVKNDRSDAVWIADFMRISNTPASSRDIPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XJY4</accession>
    <name>A0A0P6XJY4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glutamate synthase (NADPH)</fullName>
            <ecNumber evidence="3">1.4.1.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ADN00_12325</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>2 L-glutamate + NADP(+) = 2-oxoglutarate + H(+) + L-glutamine + NADPH</text>
            <dbReference type="Rhea" id="RHEA:15501"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:58359"/>
            <dbReference type="EC" id="1.4.1.13"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the glutamate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.1.13" evidence="3"/>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76175.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12325"/>
    <dbReference type="EnsemblBacteria" id="KPL76175">
        <property type="protein sequence ID" value="KPL76175"/>
        <property type="gene ID" value="ADN00_12325"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3945"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004355">
        <property type="term" value="F:glutamate synthase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006537">
        <property type="term" value="P:glutamate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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    <dbReference type="CDD" id="cd02808">
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        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
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        <property type="entry name" value="GltB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002932">
        <property type="entry name" value="Glu_synthdom"/>
    </dbReference>
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        <property type="entry name" value="Fer4_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01645">
        <property type="entry name" value="Glu_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="16"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="9">
        <location>
            <begin position="69"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="25"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="28"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
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        <location>
            <position position="31"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
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        <location>
            <position position="35"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
    </feature>
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        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
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        <location>
            <position position="82"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
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            <position position="85"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
        </ligand>
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        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00023004"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
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        </source>
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        </source>
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        </source>
    </evidence>
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        </source>
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            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="545" mass="59163" checksum="9DFEA721CE6954BF" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKL0</accession>
    <name>A0A0P6XKL0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_16510</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16510"/>
    <dbReference type="EnsemblBacteria" id="KPL72075">
        <property type="protein sequence ID" value="KPL72075"/>
        <property type="gene ID" value="ADN00_16510"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="409" mass="46520" checksum="860B935B76FEAD69" modified="2016-01-20" version="1">MIISTPEIHTNDGRVIVSARISYDHRPLNKPDIAWFSFPEKYAPFVSGRADPFAVSLLPLAQVLGEDLTIQGSLSPRLLNGMREYQQVMAYWIPNQMRLVNIIANDLQPLPAQRAGKNLVTLFSGGVDSSHSLVSHLPEYQTDLAYQVRGALFIHGLDIPFQNQASYLESLQIFERHLTPLGIELISCATNLHYFSSGLLKWGIAHAGVIFGAGLALDGWIANLVVPSSYSLDELIPRGISPMVDHLLSTETLKIIHHGATSSRVEKVAAISNWEPAQQFLRVCVDEKYRFAVNNCSKCEKCIRTMTMLEICGTLPAFKTFKQPFGIHDIFRWTPHYEFGEVWVLQTIQFARSQAKHQYIFPLQVAHIKGRIRNWIYRRIPRWLFKFLKAQKFPYQQDLFNPDFLPPGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XL83</accession>
    <name>A0A0P6XL83_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">GCN5 family acetyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10455</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062945.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76989">
        <property type="protein sequence ID" value="KPL76989"/>
        <property type="gene ID" value="ADN00_10455"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2562"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="5"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="154" mass="18206" checksum="C96F71C475758797" modified="2016-01-20" version="1">MNRGIKIRKAAPRDVETLAFFNTAMAWETEGKRLDPETITRGLQNLLRRPELGYYLVAELDGEVAGALMITTEWSDWRNGLFWWIQSVYVRPEYRRQGVFKRLFVEVENLAHQEAEVCGLRLYVEHTNHTAQRTYRALGMQESGYRLYEKEFDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XL84</accession>
    <name>A0A0P6XL84_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">LuxR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_00360</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060969.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00360"/>
    <dbReference type="EnsemblBacteria" id="KPL81031">
        <property type="protein sequence ID" value="KPL81031"/>
        <property type="gene ID" value="ADN00_00360"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3465"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="6"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="147"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL81031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="225" mass="24807" checksum="DDB339FD720AB797" modified="2016-01-20" version="1">MSSEIRLLLVDDHIVVRKGIIAMLETEPDLSVIGECSNGQEAIEAYALLKPDVVLMDLVMPVLDGVEAIRAIKKSSPKARILVLTSFTSDERVFAAIEAGATGYLLKDSDPEDLVKSIHQVYKGESSLHPMIARKLLNELTQQSSKKKSSEEDLTDREIEVLKYIARGLSNQEIAEQMVVSKPTVHTHVSNILSKLQLSNRTQAALFAIREGYITFSSALGESEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XM01</accession>
    <name>A0A0P6XM01_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_08890</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77355.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062766.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08890"/>
    <dbReference type="EnsemblBacteria" id="KPL77355">
        <property type="protein sequence ID" value="KPL77355"/>
        <property type="gene ID" value="ADN00_08890"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4011"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="7"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="41"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL77355.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="338" mass="36863" checksum="20C29D8DCBA36627" modified="2016-01-20" version="1">MAQSGEIVFEGVSKSFTDGSIPAVNGVSFRVAAGNMVVLLGPSGCGKTTLLKMVNRLYDPTEGKIWLGGQEIHTLPVNELRRHIGYVIQQVGLFPHMTIRKNIAVVPRLLGWDDQKIDARVEELLDLIGLPTSYLSRFPRQLSGGEQQRVGLARALAADPSILLMDEPFAAVDAINRERLQGELLGLHCKLAKTILFVTHDVEEAFRLADKIIVMRAGKVVQYGTPIEIVTHPADAFVEDLVGSNNLLRRLSLVNVQSILKAREEMGIPAVLPEADAEETAVLRPEDDLRSALSLLLSSGRDTLRVENASGIPLGEVGFSDLRSMLFAAPSSKKKNCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XMD2</accession>
    <name>A0A0P6XMD2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_14860</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SorC transcriptional regulatory family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000036">
        <property type="protein sequence ID" value="KPL73071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063819.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000036.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL73071">
        <property type="protein sequence ID" value="KPL73071"/>
        <property type="gene ID" value="ADN00_14860"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007324">
        <property type="entry name" value="Sugar-bd_dom_put"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04198">
        <property type="entry name" value="Sugar-bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r4" evidence="3">
        <location>
            <begin position="18"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar-bind" evidence="2">
        <location>
            <begin position="63"/>
            <end position="313"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010466"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL73071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="315" mass="34529" checksum="7FE3D54196B65183" modified="2016-01-20" version="1">MYDEIDQQRILYKIAKSYYEDGLTQKQIGKRLGLSRIKVSRMLKQAREQKIVQISLSAPEDGRSDLEHAIEKKYGIDEVITTTPPSYNREGVIRALGPLAAEALVRSIKGDEVIGLTWGSSLLSVVDSLPAEHWPAIRVVQMLGGMSQPDAEINGVDLTRRMAQAFEARPIILSAPGVVNSPEVRNALINAPAVSKALSMAAAAQIAVVGLGVFSPDSAVLQNEIFTPQEVDRLVAKGAIGDICLQYFNQNGERIEDPIHNRIIGLELHQVKRISRVIGVAGGEEKWIAIRAALRAKLINVLVTDDRTAEMLLRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XMD4</accession>
    <name>A0A0P6XMD4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_18745</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064566.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70083">
        <property type="protein sequence ID" value="KPL70083"/>
        <property type="gene ID" value="ADN00_18745"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="181" mass="22112" checksum="E0B6BC1F5FDD50EA" modified="2016-01-20" version="1">MLWGLKLFEIPIYRLSPDDFDKELERIESEFKDEITFCTSHELANLAPEKITEFETQADYWLSINPISRSYLYNDIIGYIQLLCDGTRIRAEYWWINKKRILRDPKNKLFRYRDKLFEFYILSNSTNESISKQILKSFENIKKDNRFKKRYFDLETVENLVYFIDWLGFYKSQFQNDPLFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XMD7</accession>
    <name>A0A0P6XMD7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Endoribonuclease YbeY</fullName>
            <ecNumber evidence="7">3.1.-.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">ybeY</name>
        <name evidence="8" type="ORF">ADN00_00210</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the endoribonuclease YbeY family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.-.-" evidence="7"/>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060942.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00210"/>
    <dbReference type="EnsemblBacteria" id="KPL81009">
        <property type="protein sequence ID" value="KPL81009"/>
        <property type="gene ID" value="ADN00_00210"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3436"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:endoribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00009">
        <property type="entry name" value="Endoribonucl_YbeY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023091">
        <property type="entry name" value="MetalPrtase_cat_dom_sf_prd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002036">
        <property type="entry name" value="YbeY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020549">
        <property type="entry name" value="YbeY_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46986">
        <property type="entry name" value="PTHR46986"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02130">
        <property type="entry name" value="YbeY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00043">
        <property type="entry name" value="TIGR00043"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01306">
        <property type="entry name" value="UPF0054"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 7" id="KW-0255">Endonuclease</keyword>
    <keyword evidence="5 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2 7" id="KW-0540">Nuclease</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="7" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6 7" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="7">
        <location>
            <position position="115"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="119"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="125"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <note>catalytic</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010875"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00009"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL81009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="160" mass="17802" checksum="A0FC5CEC42863FC1" modified="2016-01-20" version="1">MKPIVNQVIAEPFQPLLHSFPFEPVVQAVLAQQGINKQVELSIVIDDDDYLRQLNLDYRGIDASTDVLSFPSNELDPDSNAEYIGDIIISYPTALRQAENSGHHVNNEITLLITHGVLHLLGYDHATPDEKDRMWKAQSEILKSLSCDLGRVPGEEADLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XMJ9</accession>
    <name>A0A0P6XMJ9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_00650</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00650"/>
    <dbReference type="EnsemblBacteria" id="KPL81073">
        <property type="protein sequence ID" value="KPL81073"/>
        <property type="gene ID" value="ADN00_00650"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL81073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="69" mass="7207" checksum="2FCB2B7654106B9A" modified="2016-01-20" version="1">MLNTAKVGQMIPLKWRLLDGSGNPVTSLTSSAVTLTVSPHTCPSGVPVDTIETYTSGTTVLQNLGDGNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XMR0</accession>
    <name>A0A0P6XMR0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GyrI-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_08845</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000022">
        <property type="protein sequence ID" value="KPL77693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062638.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000022.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08845"/>
    <dbReference type="EnsemblBacteria" id="KPL77693">
        <property type="protein sequence ID" value="KPL77693"/>
        <property type="gene ID" value="ADN00_08845"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1491"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029442">
        <property type="entry name" value="GyrI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011256">
        <property type="entry name" value="Reg_factor_effector_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008319">
        <property type="entry name" value="UCP031644"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06445">
        <property type="entry name" value="GyrI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF031644">
        <property type="entry name" value="UCP031644"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55136">
        <property type="entry name" value="SSF55136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GyrI-like" evidence="1">
        <location>
            <begin position="20"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF06445"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="205" mass="23697" checksum="2BA5706ED71AE0AB" modified="2016-01-20" version="1">MEKLDLKKQPGLFYQPSPKQPQIVNLPTMNFLMIDGTGNPNTSTLYQQAVEALYSVSYTLKFTCKKELGKDYGVMPLEGLWWGTRIDQHVFSEADKDQFQWTMMIMQPDFITPEMVERATREAAAKKDLPLAANLRFESFTEGTVVQIMHIGPFDTEGPTVETMHNFAFEQGYHLRGKHHEIYLSDPRRTDPSKWKTIVRHPIEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XN43</accession>
    <name>A0A0P6XN43_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">PMT_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ADN00_08345</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77876.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77876">
        <property type="protein sequence ID" value="KPL77876"/>
        <property type="gene ID" value="ADN00_08345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038731">
        <property type="entry name" value="RgtA/B/C-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13231">
        <property type="entry name" value="PMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="57"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="91"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="129"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="155"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="200"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="264"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="304"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="360"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="404"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="486"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="512"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="543"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="576"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="domain" description="PMT_2" evidence="9">
        <location>
            <begin position="264"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL77876.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="721" mass="80310" checksum="4683A35FA3905CDB" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XP36</accession>
    <name>A0A0P6XP36_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Polysaccharide biosynthesis protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_10660</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the DegT/DnrJ/EryC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062981.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10660"/>
    <dbReference type="EnsemblBacteria" id="KPL77020">
        <property type="protein sequence ID" value="KPL77020"/>
        <property type="gene ID" value="ADN00_10660"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2606"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00616">
        <property type="entry name" value="AHBA_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000653">
        <property type="entry name" value="DegT/StrS_aminotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30244">
        <property type="entry name" value="PTHR30244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01041">
        <property type="entry name" value="DegT_DnrJ_EryC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000390">
        <property type="entry name" value="PLP_StrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="208"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL77020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="394" mass="43245" checksum="79A4DD6EDE5DE343" modified="2016-01-20" version="1">MTHNNSPKITMSAPDLTDAERQAVWEVINTPMLSIGPRIQAFEESFRRYTGCQHAIGVNSGTSGLHLCVRAAGVGMGDRVITSPFSFVSSTNVLLFENAVPVFVDVDERTGNLDPVLTAQAAADLAEGGAAAQRWLPRRGAEQSGALKALLAVDVFGQPADYDLLSPIARQHNLKLIEDSCEALGAQYKNRMAGMLGDYGVFAFYPNKQITTGEGGMIVTNDSAAAELMTALRNQGRAPGDTWLSHTYLGYNYRMDEMSAALGTAQMARIEELLVSRQRVADLYNQHLAGLPGIEIPYLAPETTRVSWFVYVIRVARGVDREALAARLAQRGIPVRPYFLPIHLQPYMVERFGYREGDFPITEDLGRRGLALPFSGKMDEEQVAYVCQGLRELL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XPT6</accession>
    <name>A0A0P6XPT6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_09065</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062677.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09065"/>
    <dbReference type="EnsemblBacteria" id="KPL77276">
        <property type="protein sequence ID" value="KPL77276"/>
        <property type="gene ID" value="ADN00_09065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL77276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="76" mass="8348" checksum="957B1FB1A43124B2" modified="2016-01-20" version="1">MTISHTDSVAIFEIQVKGSLAPAWSDWFAGFDLSSDENGNTIMVGPVIDQAELHGVLERIRDLGLQLLSVRQVTNH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQ19</accession>
    <name>A0A0P6XQ19_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Flagellar basal body protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_17145</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Bacterial flagellum basal body</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the flagella basal body rod proteins family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71417.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064274.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17145"/>
    <dbReference type="EnsemblBacteria" id="KPL71417">
        <property type="protein sequence ID" value="KPL71417"/>
        <property type="gene ID" value="ADN00_17145"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001444">
        <property type="entry name" value="Flag_bb_rod_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020013">
        <property type="entry name" value="Flagellar_FlgE/F/G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010930">
        <property type="entry name" value="Flg_bb/hook_C_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037925">
        <property type="entry name" value="FlgE/F/G-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00460">
        <property type="entry name" value="Flg_bb_rod"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06429">
        <property type="entry name" value="Flg_bbr_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117143">
        <property type="entry name" value="SSF117143"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03506">
        <property type="entry name" value="FlgEFG_subfam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flg_bb_rod" evidence="3">
        <location>
            <begin position="5"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="domain" description="Flg_bbr_C" evidence="4">
        <location>
            <begin position="179"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362116"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00460"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF06429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL71417.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="252" mass="26916" checksum="BD102BB453D27FB8" modified="2016-01-20" version="1">MIKGFYAAASAMLSGMYRQEVLSHNVANIDTPGFKQILTSMEDFMTTEAYTTPGVVGSPSLRHLGSLGLGVEMAEDTIDFTQGAMNATGNDLDVAIEGTGFFRIRTPEGERYTRDGRMVRDAEGQLVTVDGFPYLSDNGQPITIDQGIVSVSREGLISVNGEEAGSLGIAVFEDPGAVLTRTAGNYFESSAAPGTEDGGVVLQGYLESSNANPTRLMTHMVEVLRSYQAAQQMVQNQDELLGRSISVLGRIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQU4</accession>
    <name>A0A0P6XQU4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_04825</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061822.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79174">
        <property type="protein sequence ID" value="KPL79174"/>
        <property type="gene ID" value="ADN00_04825"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13302">
        <property type="entry name" value="Acetyltransf_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="7"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="184" mass="21504" checksum="A716A4A8509D78E0" modified="2016-01-20" version="1">MIYAERIRLRAVERSDLPSFVAFFNDPEVRANLSVYLPMSLASEEQWFENNLKRQPEEQQYAIDARDGEGWKLIGSCGFYNLSMRDRSAEIGLSIGDKAYWNQGYGQETVRLLLRHGFNTLNLNRIVLQVLENHDRAIHIYEKAGFVLEGRQRQARYRDGQYIDVLLMSVLKSEWLDLLSKQEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XR96</accession>
    <name>A0A0P6XR96_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_03105</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000014">
        <property type="protein sequence ID" value="KPL79329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061498.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000014.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03105"/>
    <dbReference type="EnsemblBacteria" id="KPL79329">
        <property type="protein sequence ID" value="KPL79329"/>
        <property type="gene ID" value="ADN00_03105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10320">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003737">
        <property type="entry name" value="GlcNAc_PI_deacetylase-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024078">
        <property type="entry name" value="LmbE-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12993">
        <property type="entry name" value="PTHR12993"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02585">
        <property type="entry name" value="PIG-L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102588">
        <property type="entry name" value="SSF102588"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="246" mass="28026" checksum="7B71DDF1C76A93E1" modified="2016-01-20" version="1">MKWIYLSPHLDDVVLSCGGIIWQQRSAGEDVEVWTLCAGDPPPGKISTYATQLHARWKLLKEPVAARREEDQQACQILGVKWQHFGLPDIIYRRQPGGDFQIRADEDLFRPLSPYKENLVPLLAGQLKSELPADARVVSPMGVGGHTDHRMTRAIAERLPHELWYYPEFPYTARHPGAMDSLISPDWTEVTYTVSAQALSAWQTAIAAYRSQISTFWQSESDMRVSLEAYWYADGGKRLWRANVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XSV9</accession>
    <name>A0A0P6XSV9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Lactamase_B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_11570</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL75997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063175.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11570"/>
    <dbReference type="EnsemblBacteria" id="KPL75997">
        <property type="protein sequence ID" value="KPL75997"/>
        <property type="gene ID" value="ADN00_11570"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07713">
        <property type="entry name" value="DHPS-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041712">
        <property type="entry name" value="DHPS-like_MBL-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="72"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00753"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL75997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="310" mass="33632" checksum="B3526DCE7A85EDBF" modified="2016-01-20" version="1">MLKKILLGIFLAGILLIVSVFALAAMRYGLELGKPTEAAPAAMSLEELGSTKSLQIVPLYEFDLSSDLLAGGHGVSYQITTDQANILLDFGYNETNTYPSVLEDNMGSLGIALSDFDAIVISHDHPDHVGSVGNWLSNTFSVGRQPDDLSNMTVYVPVKMEHPNATLTVVDQPVKIAEGVATLGPMYFDFSFPFNVLKKWHYEQPLVVNVEGVGLILITGCGHPGIERMAARAEQVFGEPVVGVIGGLHNITQTPEQLAEDIAFIQNLNPVLVAVSPHDSLPEQIDLFRQEFGDTYRDIRLGEAIVISAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUI5</accession>
    <name>A0A0P6XUI5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_14990</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000036">
        <property type="protein sequence ID" value="KPL73091.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063844.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000036.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL73091">
        <property type="protein sequence ID" value="KPL73091"/>
        <property type="gene ID" value="ADN00_14990"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1862"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="26"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="91"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="151"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="184"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="241"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="284"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="342"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="147"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL73091.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="374" mass="41913" checksum="D816D11466199B8D" modified="2016-01-20" version="1">MSTKGIGNRESISSPIDWLASSLGRILISIFVPILTFIGLWQGFLFLRDSNAPQIVTALVAIIWGVGGVAILYIVSNWLIEQLPDVWTRRLSPFVFVGPAVAILTWFLFLPTLRTFYLSLFNNNSTVFVGLQNYVAAFTERAMLESFRNNLYWLVIGTSLSVIFGLLIAVLADRSSFESIAKSLIFLPMAISFVGAGVIWRFIYYYRPANMVQTGLLNAIVTLFGGEPQAWTTLLQPWNNFFLIVIMVWLQTGYAMVIFSSAIKGVPEELLEAARVDGANEFQIFFKIIIPQIQGTIITVTTTIVIFSLKIFDVVLVMTGGQYGTEVIATQFYRQFFSNRNFGYGSAISIVLLIAVIPIMIYNLSQFGKREVFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUY8</accession>
    <name>A0A0P6XUY8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_03835</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79031">
        <property type="protein sequence ID" value="KPL79031"/>
        <property type="gene ID" value="ADN00_03835"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="74" mass="8472" checksum="F28F2DC0782BEDEE" modified="2016-01-20" version="1">MESQSAYGLMGLFYLIWMSWELQEQEDGGFRAGMETVRVRIARPPSTPPYLVLINRKSKKMVGFGRGGRPFESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XV13</accession>
    <name>A0A0P6XV13_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_04100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061689.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04100"/>
    <dbReference type="EnsemblBacteria" id="KPL79068">
        <property type="protein sequence ID" value="KPL79068"/>
        <property type="gene ID" value="ADN00_04100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="55"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="134" mass="14523" checksum="5D65878675E444DB" modified="2016-01-20" version="1">MGASEERLKILQMLQDGIINAEEAAGLLDALGEAESPAGASGPAGARWEGESSGAKPRWLRVQVTDTDTGKKRVNVRLPVGMMKAGMKMGMRFAPEIEGMDLGELFQFVERGELGKVVDVYDDEDGEHVEVFLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XVJ9</accession>
    <name>A0A0P6XVJ9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_03015</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000014">
        <property type="protein sequence ID" value="KPL79315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061481.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000014.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03015"/>
    <dbReference type="EnsemblBacteria" id="KPL79315">
        <property type="protein sequence ID" value="KPL79315"/>
        <property type="gene ID" value="ADN00_03015"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2012"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1902531">
        <property type="term" value="P:regulation of intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="6">
        <location>
            <begin position="7"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="7">
        <location>
            <begin position="308"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="5">
        <location>
            <begin position="424"/>
            <end position="639"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL79315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="643" mass="71436" checksum="2EACB71635C12214" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XVL1</accession>
    <name>A0A0P6XVL1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_03125</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000014">
        <property type="protein sequence ID" value="KPL79333.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03125"/>
    <dbReference type="EnsemblBacteria" id="KPL79333">
        <property type="protein sequence ID" value="KPL79333"/>
        <property type="gene ID" value="ADN00_03125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="800"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="306"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="327"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79333.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="829" mass="88215" checksum="A178536B498B385D" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XW64</accession>
    <name>A0A0P6XW64_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidase_C39_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_02310</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000010">
        <property type="protein sequence ID" value="KPL79653.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02310"/>
    <dbReference type="EnsemblBacteria" id="KPL79653">
        <property type="protein sequence ID" value="KPL79653"/>
        <property type="gene ID" value="ADN00_02310"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2678"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039564">
        <property type="entry name" value="Peptidase_C39-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13529">
        <property type="entry name" value="Peptidase_C39_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="domain" description="Peptidase_C39_2" evidence="3">
        <location>
            <begin position="113"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="373"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="42"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="44"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL79653.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="419" mass="46554" checksum="65019A257A865317" modified="2016-01-20" version="1">MVIAGAALSRTPAVRNRLDWRIDLALTQLRFKLDPVGALPTPQTSGLPLPPPQVNTTSISPTPPATASVAAPGLTQAPLPTATPTLEPTPTFPPLPAKAILTPPPMRAGDAQDWNNCGPATLALNLRFYGWGGDQYTISDVIKPIRADRNVNVEDMTAYVNEEAAPLRALFRVGGSLEQVKRLLANGFPVMIEVGFVLPADAQGITGPSDDRWTGHYLFVTGYDDDRQLFIVQDVYEGGNHVVTYQDADKRWQAFNRVYILIYQPEREAELQSLLASDWDARSNRQNALKQAQAETRTEPRNAFAWFNLGTNLVYFERYAEAAEAYNQARQIGLPQRMLRYQFGPFLAYFHAGMFEELNTIADYALEVTPNSEEGLLWKGWALYRQGLSQEALQSFQKALEARPGYGDASYAIQFVLEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XWB7</accession>
    <name>A0A0P6XWB7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 2">Peptidyl-tRNA hydrolase</fullName>
            <shortName evidence="1">PTH</shortName>
            <ecNumber evidence="1 2">3.1.1.29</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">pth</name>
        <name evidence="4" type="ORF">ADN00_01215</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 2">
            <text>an N-acyl-L-alpha-aminoacyl-tRNA + H2O = a tRNA + an N-acyl-L-amino acid + H(+)</text>
            <dbReference type="Rhea" id="RHEA:54448"/>
            <dbReference type="Rhea" id="RHEA-COMP:10123"/>
            <dbReference type="Rhea" id="RHEA-COMP:13883"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:59874"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:138191"/>
            <dbReference type="EC" id="3.1.1.29"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="1">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the PTH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.29" evidence="1 2"/>
    <dbReference type="EMBL" id="LGCL01000003">
        <property type="protein sequence ID" value="KPL80856.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061139.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01215"/>
    <dbReference type="EnsemblBacteria" id="KPL80856">
        <property type="protein sequence ID" value="KPL80856"/>
        <property type="gene ID" value="ADN00_01215"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1991"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004045">
        <property type="term" value="F:aminoacyl-tRNA hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00462">
        <property type="entry name" value="PTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00083">
        <property type="entry name" value="Pept_tRNA_hydro_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001328">
        <property type="entry name" value="Pept_tRNA_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018171">
        <property type="entry name" value="Pept_tRNA_hydro_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036416">
        <property type="entry name" value="Pept_tRNA_hydro_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17224">
        <property type="entry name" value="PTHR17224"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01195">
        <property type="entry name" value="Pept_tRNA_hydro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53178">
        <property type="entry name" value="SSF53178"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00447">
        <property type="entry name" value="pth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01195">
        <property type="entry name" value="PEPT_TRNA_HYDROL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU000673"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL80856.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="210" mass="22746" checksum="0133C3FDF1BD5520" modified="2016-01-20" version="1">MPPALSETLIQNPDAPFLLVGLGNPGREYKENRHNIGFMLIDRLCEQWGVRMSRMQNKALVASTNQGGRKILLAKPQTFMNLSGQAVAPLLKFYKVPLENLLVAHDDLDIPFGTLRIRPGGGPGGQKGVGSIIQLLGTQQFPRLRLGIGRPPGQMDAAAYVLQDFCAGDQEVLKMVLDRAADAAVMFVEKGLNPAMNLFNGGLPGVDKVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XY59</accession>
    <name>A0A0P6XY59_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Antibiotic biosynthesis monooxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_00575</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81061.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061007.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00575"/>
    <dbReference type="EnsemblBacteria" id="KPL81061">
        <property type="protein sequence ID" value="KPL81061"/>
        <property type="gene ID" value="ADN00_00575"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007138">
        <property type="entry name" value="ABM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011008">
        <property type="entry name" value="Dimeric_a/b-barrel"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03992">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54909">
        <property type="entry name" value="SSF54909"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51725">
        <property type="entry name" value="ABM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABM" evidence="1">
        <location>
            <begin position="2"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51725"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL81061.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="101" mass="11910" checksum="BB5F072E759B1905" modified="2016-01-20" version="1">MHIVLVHARVKPEWIEDFKSACRDNAENSNHEAGVIKFDVVQQADDLTHFILIEMYKDENAAKDHKTTAHYLRWRDRVADMMAEPRQGIIFNEVYVRREDA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XZ31</accession>
    <name>A0A0P6XZ31_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Ribosomal protein S12 methylthiotransferase RimO</fullName>
            <shortName evidence="7">S12 MTTase</shortName>
            <shortName evidence="7">S12 methylthiotransferase</shortName>
            <ecNumber evidence="7">2.8.4.4</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Ribosomal protein S12 (aspartate-C(3))-methylthiotransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="7">Ribosome maturation factor RimO</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rimO</name>
        <name evidence="11" type="ORF">ADN00_13900</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>[sulfur carrier]-SH + AH2 + L-aspartate(89)-[ribosomal protein uS12]-hydrogen + 2 S-adenosyl-L-methionine = 3-methylsulfanyl-L-aspartate(89)-[ribosomal protein uS12]-hydrogen + 5'-deoxyadenosine + [sulfur carrier]-H + A + 2 H(+) + L-methionine + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:37087"/>
            <dbReference type="Rhea" id="RHEA-COMP:10460"/>
            <dbReference type="Rhea" id="RHEA-COMP:10461"/>
            <dbReference type="Rhea" id="RHEA-COMP:14737"/>
            <dbReference type="Rhea" id="RHEA-COMP:14739"/>
            <dbReference type="ChEBI" id="CHEBI:13193"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:17499"/>
            <dbReference type="ChEBI" id="CHEBI:29917"/>
            <dbReference type="ChEBI" id="CHEBI:29961"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:64428"/>
            <dbReference type="ChEBI" id="CHEBI:73599"/>
            <dbReference type="EC" id="2.8.4.4"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="7">Binds 2 [4Fe-4S] clusters. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the methylthiotransferase family. RimO subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.4.4" evidence="7"/>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063625.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000032.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13900"/>
    <dbReference type="EnsemblBacteria" id="KPL74380">
        <property type="protein sequence ID" value="KPL74380"/>
        <property type="gene ID" value="ADN00_13900"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1358"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0103039">
        <property type="term" value="F:protein methylthiotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0018339">
        <property type="term" value="P:peptidyl-L-beta-methylthioaspartic acid biosynthetic process from peptidyl-aspartic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006400">
        <property type="term" value="P:tRNA modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01865">
        <property type="entry name" value="MTTase_RimO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005839">
        <property type="entry name" value="Methylthiotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020612">
        <property type="entry name" value="Methylthiotransferase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013848">
        <property type="entry name" value="Methylthiotransferase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038135">
        <property type="entry name" value="Methylthiotransferase_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005840">
        <property type="entry name" value="Ribosomal_S12_MeSTrfase_RimO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041582">
        <property type="entry name" value="RimO_TRAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002792">
        <property type="entry name" value="TRAM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43837">
        <property type="entry name" value="PTHR43837"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18693">
        <property type="entry name" value="TRAM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00919">
        <property type="entry name" value="UPF0004"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00274">
        <property type="entry name" value="ribosomal_protein_S12_methylth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00089">
        <property type="entry name" value="TIGR00089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01125">
        <property type="entry name" value="TIGR01125"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51449">
        <property type="entry name" value="MTTASE_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01278">
        <property type="entry name" value="MTTASE_RADICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50926">
        <property type="entry name" value="TRAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 7" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7" id="KW-0408">Iron</keyword>
    <keyword evidence="6 7" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="MTTase N-terminal" evidence="9">
        <location>
            <begin position="6"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="Radical SAM core" evidence="10">
        <location>
            <begin position="147"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="TRAM" evidence="8">
        <location>
            <begin position="381"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="15"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="51"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="161"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="165"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="168"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01865"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL74380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="445" mass="49403" checksum="D24D23D2FFA06743" modified="2016-01-20" version="1">MKRNHQTYFLASLGCAKNTVDSESMALLLNSAGYRPVEDPHKADVMIVNTCGFIHDARQESIEVLQDLSKSKKRGQILLAAGCLPQRDAELITQAVPKIDGLLSTRRWMQIVQFIETIRSQPSSHALYDIPPDNMPSLEPGGVLRSAIQGGSAYLKIADGCRRGCAYCSIPLIKGPVSSRKMEDILADARVLEQAGVQELILIAQDTTDYGSDLGLKDGLSQLLEQMVREVPSIPWIRLMYTFPGYITDRLIDLMASSRQILPYLDLPLQHAHPDVLKSMHRPSDMEWVRGTLAKMRSKIPALALRTTFIVGYPTETDERFSALLDFTREIRFDHLGAFTYSFEPGTRGAPLGDPVSEEIKQERLQQLMQIQEEIALENNRAFVGREMQVLIDGAGDGISIGRTYRDAPEVDGLVILAGETEVGSLVNARITQAMPHDFTAEIIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y038</accession>
    <name>A0A0P6Y038_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DnaA_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_05440</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78694.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061960.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05440"/>
    <dbReference type="EnsemblBacteria" id="KPL78694">
        <property type="protein sequence ID" value="KPL78694"/>
        <property type="gene ID" value="ADN00_05440"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024633">
        <property type="entry name" value="DnaA_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038454">
        <property type="entry name" value="DnaA_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11638">
        <property type="entry name" value="DnaA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DnaA_N" evidence="2">
        <location>
            <begin position="20"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="273"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="273"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF11638"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78694.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="297" mass="33957" checksum="467000B7E41C1AAC" modified="2016-01-20" version="1">MEHIVQSKPPSFKVTGYRDAWQMVLNQLQMEMSRTLFDTWVQPLHPLGFKEGVFTLGAFNPYARDWVDNRLRSRITRLLEGVFGEAIDLRVVVSNGFSNQPAAESEQDESEEESDGDTAISDTLPEDIEPGKKTKKVAAKPAQPSPRKVMLQRAYGSKRAAVIQPERGMFVTLYFLQQWQPIIGHSAVAIILASRSMCYWNPLTGELRNEVETEMAELAKRAAVSVRTVKDVLNQELVKQYFLRYRVRRVMTPNGIRTAGIILQVRMDDPLTPEDQQEHGLQEEEHWYSVEFDGEED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y2H5</accession>
    <name>A0A0P6Y2H5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="10">Multidrug ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ADN00_04555</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061772.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79133">
        <property type="protein sequence ID" value="KPL79133"/>
        <property type="gene ID" value="ADN00_04555"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="54"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="136"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="238"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="281"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="9">
        <location>
            <begin position="19"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="8">
        <location>
            <begin position="335"/>
            <end position="571"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="370"/>
            <end position="377"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL79133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="580" mass="63564" checksum="C46D97C1B11749D0" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y2J3</accession>
    <name>A0A0P6Y2J3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_04670</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79151.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061794.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04670"/>
    <dbReference type="EnsemblBacteria" id="KPL79151">
        <property type="protein sequence ID" value="KPL79151"/>
        <property type="gene ID" value="ADN00_04670"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL79151.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="259" mass="28115" checksum="D359014761351A47" modified="2016-01-20" version="1">MLHVKNLSVSYSGQRVLSHIDLRVARGEILGVIGPNGVGKSTLIRALSASIPVEQGTVTVLGQDVSTLPTDARARLIAVVPQARALPPAFTGWEVVLLGRTPHIGWLGNLSAHDQEIARLAMQRTDTLHLAKRHVAEMSGGEQQRLLLARALCQSSPVLLLDEPTTHLDLKYQYNLLDLVRRLAREVGLTILLTLHDLNLVSRYTDRVALLVDGRLEALDTPAKVLTASLLSRAYQIPLIVIADRQSGQAAILPASRAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y2T2</accession>
    <name>A0A0P6Y2T2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_03280</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79224">
        <property type="protein sequence ID" value="KPL79224"/>
        <property type="gene ID" value="ADN00_03280"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="59" mass="6012" checksum="0A0311147B86D643" modified="2016-01-20" version="1">MSGGSAHGNAAAIKRTAHRRGVARRRPAGGDSARPQRRSAGLDQPGRAAGRQAPQQAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y3A1</accession>
    <name>A0A0P6Y3A1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_02870</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000013">
        <property type="protein sequence ID" value="KPL79389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061451.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000013.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02870"/>
    <dbReference type="EnsemblBacteria" id="KPL79389">
        <property type="protein sequence ID" value="KPL79389"/>
        <property type="gene ID" value="ADN00_02870"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2209"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="4"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="125"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="125"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL79389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="225" mass="25576" checksum="6B43D400B65CE196" modified="2016-01-20" version="1">MNERILIIEDDEAIVKVLQRGLTYEGYEASAALDGESGLVMARANPPDLVVLDWMLPGMDGLEVCEKLREAGSVPILMLTAKDTVDDRVKGLDAGADDYMVKPFELEEFLARVRALLRRTQQERAVVLTFEDLSLDTSTRQASRKNRVISLTAKEYDLLELFLRHPRQVLTREVIFDRVWGYDFGGESNVLDVYIRYLRQKLESGGEARLIHTVRGVGYVMREIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y3P2</accession>
    <name>A0A0P6Y3P2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Phosphate ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_02505</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000011">
        <property type="protein sequence ID" value="KPL79572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061383.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000011.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02505"/>
    <dbReference type="EnsemblBacteria" id="KPL79572">
        <property type="protein sequence ID" value="KPL79572"/>
        <property type="gene ID" value="ADN00_02505"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2811"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015415">
        <property type="term" value="F:ATPase-coupled phosphate ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03260">
        <property type="entry name" value="ABC_PstB_phosphate_transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015850">
        <property type="entry name" value="ABC_transpr_PstB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005670">
        <property type="entry name" value="Phosp_transpt1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43423">
        <property type="entry name" value="PTHR43423"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43423:SF3">
        <property type="entry name" value="PTHR43423:SF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00972">
        <property type="entry name" value="3a0107s01c2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="13"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="45"/>
            <end position="52"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022592"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL79572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="262" mass="29384" checksum="D2FA0ADCDFB54C0D" modified="2016-01-20" version="1">MENRMKTNESVVIDVKDLNVYYGAFRAVKDVSITIPQNKITAFIGPSGCGKSTMLRSFNRMNELVPSARVHGNITLDGVNIYDPDIDPVMVRRKVGMVFQKPNPFPKSIYENVAWGAQINGYKGNMDDLVEESLRQAALWDEVKDKLNQSGLSLSGGQQQRLCIARTIAVKPEIILMDEPASALDPIATLRIEELMEKLSEDYTIIVVTHNMQQAARVSHYTAFFNMDEDRAGYLVEYGDTSAMFTNPSKKLTQDYITGRFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y3P6</accession>
    <name>A0A0P6Y3P6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Phosphate transport system permease protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">ADN00_02515</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Part of the binding-protein-dependent transport system for phosphate; probably responsible for the translocation of the substrate across the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the binding-protein-dependent transport system permease family. CysTW subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000011">
        <property type="protein sequence ID" value="KPL79581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02515"/>
    <dbReference type="EnsemblBacteria" id="KPL79581">
        <property type="protein sequence ID" value="KPL79581"/>
        <property type="gene ID" value="ADN00_02515"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2813"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005315">
        <property type="term" value="F:inorganic phosphate transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006817">
        <property type="term" value="P:phosphate ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011864">
        <property type="entry name" value="Phosphate_PstC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02138">
        <property type="entry name" value="phosphate_pstC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0592">Phosphate transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 8" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="98"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="130"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="169"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="220"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="287"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="94"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU363054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL79581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="320" mass="34259" checksum="291323E7020BDFF8" modified="2016-01-20" version="1">MAVDIDAQVTEFEVGSAGITLKENQVIRLGEEVMLIKSINGGILQVERGYLDTLAVSHRAGVEIYNGRVVTLREFFGRTEWNPQIGKFGIWSLANSTLLTSVVAILVALPLGLSAAIYLSEYASERARKILKPVLEVLAGVPTVVYGYFALNFMTPLLRNIFGKGVVEIYNTASAGIVIGILILPLVSSMSEDALSAVPRALREAAYGLGATKLETAIKVVVPAAFSGIAAAVIVAISRAIGETMIVAIAAGAGPAFTFNPFKAAETMTGHIVRISGGDLSYDSIDYNSLFAIGLMLFLMTLGLNIISQRVVKHFREEYE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y480</accession>
    <name>A0A0P6Y480_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_02115</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000009">
        <property type="protein sequence ID" value="KPL79782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061311.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000009.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02115"/>
    <dbReference type="EnsemblBacteria" id="KPL79782">
        <property type="protein sequence ID" value="KPL79782"/>
        <property type="gene ID" value="ADN00_02115"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2745"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004536">
        <property type="term" value="F:deoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01310">
        <property type="entry name" value="TatD_DNAse"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018228">
        <property type="entry name" value="DNase_TatD-rel_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015991">
        <property type="entry name" value="Hydrolase_TatD-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001130">
        <property type="entry name" value="TatD-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01026">
        <property type="entry name" value="TatD_DNase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005902">
        <property type="entry name" value="DNase_TatD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00010">
        <property type="entry name" value="TIGR00010"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01137">
        <property type="entry name" value="TATD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01090">
        <property type="entry name" value="TATD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01091">
        <property type="entry name" value="TATD_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="266" mass="28825" checksum="353D3547614BC4E0" modified="2016-01-20" version="1">MQLVDTHCHLNYTSFHDDLEAVLQRSRSHGIGRILIPGTDLPSSQLAVDLCARHPGLFAAVGVHPNDANTWQPGTPEELRQLAANPAVVAIGEIGLDFYRDHAPRDLQIAIFSAQLELAGQLQKPVVIHSRAALDDVISILETWRADLEKTGSPLAAHPGVLHSYEGGLEQASFAVEMGFKIGIGGPVTYKNALDKQAVAQNLPLEALLLETDAPFLSPHPHRGQRNEPAWVSLVAEKVAAIRGLALEQVATQTTSNAQELFAWPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y5H9</accession>
    <name>A0A0P6Y5H9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_01615</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061214.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01615"/>
    <dbReference type="EnsemblBacteria" id="KPL80568">
        <property type="protein sequence ID" value="KPL80568"/>
        <property type="gene ID" value="ADN00_01615"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1083"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032524">
        <property type="entry name" value="ABC_tran_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032781">
        <property type="entry name" value="ABC_tran_Xtn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037118">
        <property type="entry name" value="Val-tRNA_synth_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16326">
        <property type="entry name" value="ABC_tran_CTD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12848">
        <property type="entry name" value="ABC_tran_Xtn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="4"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="326"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="250"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="569"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="360"/>
            <end position="367"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL80568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="636" mass="71655" checksum="C0D86E89472CEDB1" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y5Q7</accession>
    <name>A0A0P6Y5Q7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Ribosomal_S27 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_10130</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76940.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062885.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76940">
        <property type="protein sequence ID" value="KPL76940"/>
        <property type="gene ID" value="ADN00_10130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002906">
        <property type="entry name" value="Ribosomal_S27a"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01599">
        <property type="entry name" value="Ribosomal_S27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="90"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="Ribosomal_S27" evidence="8">
        <location>
            <begin position="8"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="61"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL76940.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="171" mass="18453" checksum="7B2FE95B79F772AD" modified="2016-01-20" version="1">MPEFVTLSCPSCGAKLQIGSHVDRFACSHCGNEHVVQRDGGIVSLAPVIEQIKQVQSGVDKTASELAIARLKEEIQEIRRSMPDTSNEGCLAKVGMGLSGIAMFACIGGIMTGDGSTIAMAVVVSLIMFAVGVWLGLKEDQNKNARLKPYREAIAEKENEIERHKKLVNLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y5Y8</accession>
    <name>A0A0P6Y5Y8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10555</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77004.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10555"/>
    <dbReference type="EnsemblBacteria" id="KPL77004">
        <property type="protein sequence ID" value="KPL77004"/>
        <property type="gene ID" value="ADN00_10555"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011659">
        <property type="entry name" value="PD40"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07676">
        <property type="entry name" value="PD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77004.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="326" mass="34332" checksum="440ED8756D0643C1" modified="2016-01-20" version="1">MGLLSACQPAATAAPPATPEALPTALPAPSATPLAVTVEAMPTTPPCKRIAFALADFNSDSPQSEIYTACPDGTGLTRLTDDSAADLAPAWSPDGTRIAFASARAGGSRIFVMGAAGGEAEVLSAEGQHDMPLWIPGGEERVAYRCTDGQGRWWWEALTLSSGAVERLSEPSFDFFFQTPAWSPDGAWLAVMSLAEQAARNDGASQIHIQRADGSQERVLTSDAWANISPQWSPDGQRIAFLSERDGVYNRYGLYVMDADGSHPERIGAGFYSEGAEFAWSPDGMEIAISEPGSGGIVILDLTSGAGRPLLALEPGQSAFSPAWQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y883</accession>
    <name>A0A0P6Y883_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Elongation factor 4</fullName>
            <shortName evidence="5">EF-4</shortName>
            <ecNumber evidence="5">3.6.5.n1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Ribosomal back-translocase LepA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">lepA</name>
        <name evidence="7" type="ORF">ADN00_08320</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre-translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP-dependent manner.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>GTP + H2O = GDP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.n1"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Peripheral membrane protein</topology>
            <orientation evidence="5">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. LepA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.n1" evidence="5"/>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062522.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08320"/>
    <dbReference type="EnsemblBacteria" id="KPL77872">
        <property type="protein sequence ID" value="KPL77872"/>
        <property type="gene ID" value="ADN00_08320"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.666"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045727">
        <property type="term" value="P:positive regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03709">
        <property type="entry name" value="lepA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.2570">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00071">
        <property type="entry name" value="LepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006297">
        <property type="entry name" value="EF-4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041095">
        <property type="entry name" value="EFG_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038363">
        <property type="entry name" value="LepA_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013842">
        <property type="entry name" value="LepA_CTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035654">
        <property type="entry name" value="LepA_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43512">
        <property type="entry name" value="PTHR43512"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14492">
        <property type="entry name" value="EFG_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06421">
        <property type="entry name" value="LepA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01393">
        <property type="entry name" value="lepA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="6">
        <location>
            <begin position="2"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="14"/>
            <end position="19"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="131"/>
            <end position="134"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005454"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL77872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="598" mass="66896" checksum="12DDE17DC95F6EFD" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YB56</accession>
    <name>A0A0P6YB56_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_04675</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79152.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061795.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04675"/>
    <dbReference type="EnsemblBacteria" id="KPL79152">
        <property type="protein sequence ID" value="KPL79152"/>
        <property type="gene ID" value="ADN00_04675"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010237">
        <property type="entry name" value="Pyr-5-nucltdase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01132">
        <property type="entry name" value="C1.5.3:_5'-Nucleotidase_Like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01993">
        <property type="entry name" value="Pyr-5-nucltdase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79152.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="213" mass="24184" checksum="8BD8A127F62B3EAB" modified="2016-01-20" version="1">MHIQTLLIDLDDTIYPPRDGIWDAIGTRINSFIHNQIHLPPEQISQLRDRLYLEYGTTLRGLQIEYGIDPHQYLDYVHDIPLKELLTPNPRLQDVFSNLPQRKIIFTNSDRNHSTRVLDFFNIRPYFERIIDVLDVAPYCKPNPEAFEAALRIAGVSDLSACAIVDDNVRNIQAAAQMGLFSVHVGPPEKAPAAAHRSIARIEDLPAVLQNQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GKX5</accession>
    <name>A0A0N8GKX5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 6">Transcription termination/antitermination protein NusG</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">nusG</name>
        <name evidence="10" type="ORF">ADN00_17680</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 6">Participates in transcription elongation, termination and antitermination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the NusG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000043">
        <property type="protein sequence ID" value="KPL70914.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064419.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000043.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17680"/>
    <dbReference type="EnsemblBacteria" id="KPL70914">
        <property type="protein sequence ID" value="KPL70914"/>
        <property type="gene ID" value="ADN00_17680"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2126"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006354">
        <property type="term" value="P:DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032784">
        <property type="term" value="P:regulation of DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00948">
        <property type="entry name" value="NusG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005824">
        <property type="entry name" value="KOW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006645">
        <property type="entry name" value="NGN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036735">
        <property type="entry name" value="NGN_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043425">
        <property type="entry name" value="NusG-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001062">
        <property type="entry name" value="Transcrpt_antiterm_NusG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30265">
        <property type="entry name" value="PTHR30265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30265:SF2">
        <property type="entry name" value="PTHR30265:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00467">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02357">
        <property type="entry name" value="NusG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00338">
        <property type="entry name" value="NUSGTNSCPFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00739">
        <property type="entry name" value="KOW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00738">
        <property type="entry name" value="NGN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82679">
        <property type="entry name" value="SSF82679"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00922">
        <property type="entry name" value="nusG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 5 6" id="KW-0889">Transcription antitermination</keyword>
    <keyword evidence="3 5 6" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="1 5 6" id="KW-0806">Transcription termination</keyword>
    <feature type="domain" description="NGN" evidence="8">
        <location>
            <begin position="27"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="KOW" evidence="9">
        <location>
            <begin position="145"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="11"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022472"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000538"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00739"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL70914.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="199" mass="22916" checksum="5A17CCF53F841478" modified="2016-01-20" version="1">MEGLDASQRDVSTLSDHEAQPEGEGDDRSWYVIHCYSGYENKVRHNLEQRIETMGMKDKIFDVVIPTQEEIDVKDGKRRVVERHVFPGYVLVNMVLTEESWYVVRNTPGVTGFVGMGNDPTPLRPEEVVQILKRMEAEAPHIKVTFKVGERVRIIDGPFNDFRGTVSEIDMERTKVRVMVNFFGRETPVELDFLQVEKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMB5</accession>
    <name>A0A0N8GMB5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_13425</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74834.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063533.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000031.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74834">
        <property type="protein sequence ID" value="KPL74834"/>
        <property type="gene ID" value="ADN00_13425"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1172"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036271">
        <property type="entry name" value="Tet_transcr_reg_TetR-rel_C_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48498">
        <property type="entry name" value="SSF48498"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL74834.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="202" mass="23348" checksum="D035FDE74DD5C872" modified="2016-01-20" version="1">MDKKAEILRCGKELFSTHGFKSTGIADITKMAGIAAGTFYLYFSSKEKLFMELFLEENVKLKREILAAIDPNGDPLAVIQEMMKRNMEGMASNPILREWYNKEVFAKIEEKYREEHGLDYVDFMYTSFIEIVKNWQAEGKLRQDIDSEMIMAIFSTVIIIDEHKEDIGLQFFPKIQEYLTEFIIKGLTGTMDLPAGRQESVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMX2</accession>
    <name>A0A0N8GMX2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10975</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063057.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76490">
        <property type="protein sequence ID" value="KPL76490"/>
        <property type="gene ID" value="ADN00_10975"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.889"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="610"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="289"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="785" mass="86589" checksum="DEBD9F1F9D5439CF" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNS8</accession>
    <name>A0A0N8GNS8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_03295</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78938.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061537.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78938">
        <property type="protein sequence ID" value="KPL78938"/>
        <property type="gene ID" value="ADN00_03295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78938.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="197" mass="21815" checksum="7FB1AE7C5ED43953" modified="2016-01-20" version="1">MEMTANWHCQDRLGEWLLESLAETLGEEQMKALVARFDGGDESSKAGMKEVLAALKDWFGQPGSQGMSVQAGRNAFNLLLQKQGEELGWFSQRFRLLPKSRRIHEGLSALVNFLVELCGTSIRLEEDEHGWRCTTQGCAWGGMDGGNLDLCYFQQGLLQEFMLWASGGRLHLVNVAASAAQGEPACVIRIARQPLEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNT9</accession>
    <name>A0A0N8GNT9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_03810</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061637.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79026">
        <property type="protein sequence ID" value="KPL79026"/>
        <property type="gene ID" value="ADN00_03810"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032816">
        <property type="entry name" value="SNARE_assoc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09335">
        <property type="entry name" value="SNARE_assoc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="119"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="189" mass="20660" checksum="0963CB4EF3921DC9" modified="2016-01-20" version="1">MTYPKKLTQTSRLRTLLTILLSLGLFTALGLYLQQDWPQVKTFIQQIGPAGWAISIPLYAILGATIIPSEPITVLNSALFGPFTAALAATIGNTIAAYIEYFMGTKVSDLASFEHKKESLPWGLGKLPIHSPLLLIFGRFIPGFGSKMVSLMAGMYKVNPLRYLWTTLLTTAFGSLVFAFGGMGLIHLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GPI3</accession>
    <name>A0A0N8GPI3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">50S ribosomal subunit assembly factor BipA</fullName>
            <ecNumber evidence="2">3.6.5.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">GTP-binding protein BipA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">bipA</name>
        <name evidence="4" type="ORF">ADN00_00015</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">A 50S ribosomal subunit assembly protein with GTPase activity, required for 50S subunit assembly at low temperatures, may also play a role in translation. Binds GTP and analogs. Binds the 70S ribosome between the 30S and 50S subunits, in a similar position as ribosome-bound EF-G; it contacts a number of ribosomal proteins, both rRNAs and the A-site tRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>GTP + H2O = GDP + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="2">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <text evidence="2">Binds to ribosomes.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. BipA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.-" evidence="2"/>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL80978.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060907.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00015"/>
    <dbReference type="EnsemblBacteria" id="KPL80978">
        <property type="protein sequence ID" value="KPL80978"/>
        <property type="gene ID" value="ADN00_00015"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3399"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043022">
        <property type="term" value="F:ribosome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000027">
        <property type="term" value="P:ribosomal large subunit assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03710">
        <property type="entry name" value="BipA_TypA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.250">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00849">
        <property type="entry name" value="BipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035651">
        <property type="entry name" value="BipA_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042116">
        <property type="entry name" value="TypA/BipA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006298">
        <property type="entry name" value="TypA_GTP-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908:SF8">
        <property type="entry name" value="PTHR42908:SF8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01394">
        <property type="entry name" value="TypA_BipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 2" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0690">Ribosome biogenesis</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="2" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="2" id="KW-0820">tRNA-binding</keyword>
    <feature type="domain" description="Tr-type G" evidence="3">
        <location>
            <begin position="4"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="16"/>
            <end position="21"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL80978.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="616" mass="68794" checksum="F33F922889CCDEF2" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WK63</accession>
    <name>A0A0P6WK63_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_18655</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70070">
        <property type="protein sequence ID" value="KPL70070"/>
        <property type="gene ID" value="ADN00_18655"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="39"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="136" mass="15493" checksum="1B4975382BE82F6C" modified="2016-01-20" version="1">MKFPSLRKMALSGLVLALVGWIGLYVILFQTFPTLWPRWLFFFFLTLALSGTALPVIGFFHRRFPTTPPARGDTIVRQAIWVGVYGNLLAWLQLGRVLNLALVVFMAAAFLIIEFLLGWRERSQFHPESEAHDESA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WMP6</accession>
    <name>A0A0P6WMP6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Type III pantothenate kinase</fullName>
            <ecNumber evidence="6">2.7.1.33</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">PanK-III</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Pantothenic acid kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">coaX</name>
        <name evidence="7" type="ORF">ADN00_18640</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the phosphorylation of pantothenate (Pan), the first step in CoA biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>(R)-pantothenate + ATP = (R)-4'-phosphopantothenate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16373"/>
            <dbReference type="ChEBI" id="CHEBI:10986"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29032"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.33"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>NH4(+)</name>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
        </cofactor>
        <cofactor evidence="6">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
        <text evidence="6">A monovalent cation. Ammonium or potassium.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 6">Cofactor biosynthesis; coenzyme A biosynthesis; CoA from (R)-pantothenate: step 1/5.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the type III pantothenate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.33" evidence="6"/>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70067.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064548.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18640"/>
    <dbReference type="EnsemblBacteria" id="KPL70067">
        <property type="protein sequence ID" value="KPL70067"/>
        <property type="gene ID" value="ADN00_18640"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3037"/>
    <dbReference type="UniPathway" id="UPA00241">
        <property type="reaction ID" value="UER00352"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004594">
        <property type="term" value="F:pantothenate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015937">
        <property type="term" value="P:coenzyme A biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01274">
        <property type="entry name" value="Pantothen_kinase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004619">
        <property type="entry name" value="Type_III_PanK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34265">
        <property type="entry name" value="PTHR34265"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03309">
        <property type="entry name" value="Pan_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00671">
        <property type="entry name" value="baf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 6" id="KW-0173">Coenzyme A biosynthesis</keyword>
    <keyword evidence="4 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0630">Potassium</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="6">
        <location>
            <begin position="107"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="109"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="6"/>
            <end position="13"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="129"/>
        </location>
        <ligand>
            <name>a monovalent cation</name>
            <dbReference type="ChEBI" id="CHEBI:60242"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="132"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="184"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005225"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022993"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL70067.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="256" mass="27502" checksum="4D81C278B54D3893" modified="2016-01-20" version="1">MLLTIDIGNTNLTLGLYEGSKLGNRWRLATDHDRMPDEYGLQILGMLQHSGCSPKQLDGICLASVVPPLTGRIVKACEIYLQVPILTVDDKINTGITIRYDDPKAVGADRIVDAVAVNAFYGGPACVVDFGTATTFDAINAQGEYLGGAIAPGIGIAADALFMRAAKLPRVELQRPPSVIGYNTVHAIQSGLLFGYVALVEGMVARFRAELGPEMKVIATGGLAEIVAKETDVINIIAPWLTLDGLRILWEMNQHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WMQ2</accession>
    <name>A0A0P6WMQ2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_18685</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064557.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70076">
        <property type="protein sequence ID" value="KPL70076"/>
        <property type="gene ID" value="ADN00_18685"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="66" mass="7191" checksum="E72407C4A9319F27" modified="2016-01-20" version="1">MEKEQEDNSGTPPMRIEIAQIAETKDCQSLKAGSLCPKCKENFLDYDGMLNLVCAKCGVMDSGGFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WMY1</accession>
    <name>A0A0P6WMY1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Alpha/beta hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_19115</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70176">
        <property type="protein sequence ID" value="KPL70176"/>
        <property type="gene ID" value="ADN00_19115"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3137"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00561">
        <property type="entry name" value="Abhydrolase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="SSF53474"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="1">
        <location>
            <begin position="38"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="331" mass="37210" checksum="2FB5C91A89BF5452" modified="2016-01-20" version="1">MDEQGRPLAGSLSEKVYIEINGVQQGMFIQSRDVNNPVLLYLHGGMPDYFLSEIYPTGMEEVFTVVWWEQRGAGMSYSAETPPETLTLEQMIADTLAVTHYLRERFGQEKIYLMGHSGGTFIGIQAAARAPELYHAYIGVAQMANQRQSEVEAYKYMLAQFKANGNSEMVKKLEAAPVTLEGGIPEAYLRVRDQAMHSLGVGTMREMDSVVTGIFFPSLMSRAYTVPEKLRFWQAKANAGVSILWEDSISTDLSEKVPALDLPVYFLEGVYDYTCTYAQAKAYFDRLDAPVKGFYTFENSAHSPMFEEPEKMLEILREDVLTGGNRLADEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WN00</accession>
    <name>A0A0P6WN00_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NurA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_16820</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064213.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16820"/>
    <dbReference type="EnsemblBacteria" id="KPL71368">
        <property type="protein sequence ID" value="KPL71368"/>
        <property type="gene ID" value="ADN00_16820"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018977">
        <property type="entry name" value="NurA_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09376">
        <property type="entry name" value="NurA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00933">
        <property type="entry name" value="NurA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NurA" evidence="2">
        <location>
            <begin position="84"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="30"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL71368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="392" mass="43782" checksum="F6FEFFCA8F8188E7" modified="2016-01-20" version="1">MPLDFQQLSQQIHQMGEQAVEREERIRQHREQALHILQEVQHQAEQLREQVRQAAAMNPFLRCAIPGDENLLMRHTVAPRSAPATVLAADGSQIIPDRHAPVLFGVVNIGSLVMHVGSGETPQQAVETRLLGYDVVYTPEGVIGEDVVQLMRDSRERTYLADLAEREPAPVFTLTDGPLEPFVRDINSRPDLKRLFNDYLQALRRMCASGICAAGYVDKPGSDLLVRLLELSLLGAGELKEAGKLRPLQGVSDAALLRDLLQPGERSAIFGIQSPSAGLFPGRLGLRFFYLNVGQTGRPWLARVEIPAWVEENAEMIDQLQAVLVEQAQIMGSQPYPYILHRAHEIAVVTYEERRQVEELLAGELIRRGLPAGEVSRKQFAKDITGKRTRYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WN58</accession>
    <name>A0A0P6WN58_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_17410</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064322.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL71460">
        <property type="protein sequence ID" value="KPL71460"/>
        <property type="gene ID" value="ADN00_17410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL71460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="96" mass="10784" checksum="17BCC1FA2AC8192D" modified="2016-01-20" version="1">MTPKTIHYPTLSEDTATQREINRMLTAAVVNKRFEKLLLTNPGLAIANGYAGETFNFNEKAQLRIAAIRAESLQDFARQLIQVQEPAFTSVAYARK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WPK6</accession>
    <name>A0A0P6WPK6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">PMT_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ADN00_15990</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL71999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064042.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL71999">
        <property type="protein sequence ID" value="KPL71999"/>
        <property type="gene ID" value="ADN00_15990"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038731">
        <property type="entry name" value="RgtA/B/C-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13231">
        <property type="entry name" value="PMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="98"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="147"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="175"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="207"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="273"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="307"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="338"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="364"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="432"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="465"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="domain" description="PMT_2" evidence="9">
        <location>
            <begin position="76"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL71999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="624" mass="70723" checksum="16122BB139D9C45C" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WQ21</accession>
    <name>A0A0P6WQ21_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_15225</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72182.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063893.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72182">
        <property type="protein sequence ID" value="KPL72182"/>
        <property type="gene ID" value="ADN00_15225"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72182.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="110" mass="12508" checksum="C44328F3CFFA4EAB" modified="2016-01-20" version="1">MKTPAGKECRFFFGDYYRGRNREECRLIGNQPRPHHWTPDLCASCPVPGIVLANSCEHMRLEATVKRKFLGLKRVVEVSAFCEKTNRAVAEPYIGCGECHPLPDVFIDKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WQ69</accession>
    <name>A0A0P6WQ69_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hydrogenase assembly protein HypC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_15395</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the HupF/HypC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063923.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15395"/>
    <dbReference type="EnsemblBacteria" id="KPL72209">
        <property type="protein sequence ID" value="KPL72209"/>
        <property type="gene ID" value="ADN00_15395"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.781"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019812">
        <property type="entry name" value="Hydgase_assmbl_chp_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001109">
        <property type="entry name" value="Hydrogenase_HupF/HypC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35177">
        <property type="entry name" value="PTHR35177"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01455">
        <property type="entry name" value="HupF_HypC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00445">
        <property type="entry name" value="HUPFHYPC"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00074">
        <property type="entry name" value="hypC_hupF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01097">
        <property type="entry name" value="HUPF_HYPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006018"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="88" mass="9471" checksum="50367768F4D64A59" modified="2016-01-20" version="1">MCLGIPGKIVDIYEKDQMQMGKVDFGGVIRETCLAALPDAKIGDYTIVHAGFALNLLSEEEAKETLALLQELSDIEAELGSETGLETV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WST2</accession>
    <name>A0A0P6WST2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">PMT_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ADN00_16525</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72078.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064146.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16525"/>
    <dbReference type="EnsemblBacteria" id="KPL72078">
        <property type="protein sequence ID" value="KPL72078"/>
        <property type="gene ID" value="ADN00_16525"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038731">
        <property type="entry name" value="RgtA/B/C-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13231">
        <property type="entry name" value="PMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="57"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="117"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="187"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="239"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="265"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="313"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="375"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="401"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="428"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="459"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="domain" description="PMT_2" evidence="9">
        <location>
            <begin position="171"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF13231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL72078.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="591" mass="65038" checksum="FE86E48645DFE14A" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WSY0</accession>
    <name>A0A0P6WSY0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_15100</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063869.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15100"/>
    <dbReference type="EnsemblBacteria" id="KPL72160">
        <property type="protein sequence ID" value="KPL72160"/>
        <property type="gene ID" value="ADN00_15100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004104">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="21"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA_C" evidence="2">
        <location>
            <begin position="140"/>
            <end position="326"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL72160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="326" mass="36406" checksum="6BB078288112A85D" modified="2016-01-20" version="1">MSKKINWGILSTAHINNALFPGFKKSRRNHLLAVASRSLPKAQDYARQNNIERAYGSYQELIDDPNIQAVYIPLPNHMHAEWAVKAAAAGKHVLCEKPIALTLAEMDAIQQAAADHKVIIQEAFMYRHHPQTLRVAQLFQQGLLGEVHLIRGTFSFYLRRSDDIRLVAEYGGGSIWDVGCYPISYARHLIGRLPASVFGMQETAPSGVDLSFNGIMHFQPGLHAQFDSSFAMHSYRQLEIRGTEGTIVIPEPFSMIGKSTIHILSNGSQCKETFPAVDKYHLQLENMADAILDGQAQRVTLQDSRENTALILALLESARLQHPVEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WT76</accession>
    <name>A0A0P6WT76_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_18555</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70056.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064536.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70056">
        <property type="protein sequence ID" value="KPL70056"/>
        <property type="gene ID" value="ADN00_18555"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="53"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="257"/>
            <end position="342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL70056.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="342" mass="37598" checksum="9A4196B1EB48C945" modified="2016-01-20" version="1">MNLDIQTGVKTAFFLAIGGIFLFLYLGIRSISEGSKLLFFRKRRDLMMRGWRLILGAVGLVGLAFLLNQYAEPVAYRFFPPSPTVTLTPTITLTPTITQTPTITVTPSITVTPLYTNTPELPPEILREFSSEVTPIPGTLFSPITVALELDENFLPVNPTTEYENPVPMLYGAFSYDQMASGAQWTAVWVRLLDNAVICYETKPWDGSTGGYGYTDCAPDSNIWQPGEYDVRIFIGQQFITSGRFVIAGEVPTLTFTPTASRTPTVSPTPTNTRTPTQTSAPTRTATPRPSATITRTPTATLTRTATSTPTKTRTLPPTSTMRPTLTPRPTDTQWPTLTPEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WW11</accession>
    <name>A0A0P6WW11_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Ribosomal RNA small subunit methyltransferase I</fullName>
            <ecNumber evidence="6">2.1.1.198</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">16S rRNA 2'-O-ribose C1402 methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">rRNA (cytidine-2'-O-)-methyltransferase RsmI</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rsmI</name>
        <name evidence="8" type="ORF">ADN00_19220</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the 2'-O-methylation of the ribose of cytidine 1402 (C1402) in 16S rRNA.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>cytidine(1402) in 16S rRNA + S-adenosyl-L-methionine = 2'-O-methylcytidine(1402) in 16S rRNA + H(+) + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:42924"/>
            <dbReference type="Rhea" id="RHEA-COMP:10285"/>
            <dbReference type="Rhea" id="RHEA-COMP:10286"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:74495"/>
            <dbReference type="ChEBI" id="CHEBI:82748"/>
            <dbReference type="EC" id="2.1.1.198"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the methyltransferase superfamily. RsmI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.198" evidence="6"/>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064656.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_19220"/>
    <dbReference type="EnsemblBacteria" id="KPL70160">
        <property type="protein sequence ID" value="KPL70160"/>
        <property type="gene ID" value="ADN00_19220"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3155"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070677">
        <property type="term" value="F:rRNA (cytosine-2'-O-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000453">
        <property type="term" value="P:enzyme-directed rRNA 2'-O-methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1010.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01877">
        <property type="entry name" value="16SrRNA_methyltr_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000878">
        <property type="entry name" value="4pyrrol_Mease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035996">
        <property type="entry name" value="4pyrrol_Methylase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014777">
        <property type="entry name" value="4pyrrole_Mease_sub1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014776">
        <property type="entry name" value="4pyrrole_Mease_sub2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008189">
        <property type="entry name" value="rRNA_ssu_MeTfrase_I"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46111">
        <property type="entry name" value="PTHR46111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00590">
        <property type="entry name" value="TP_methylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005917">
        <property type="entry name" value="MTase_YraL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53790">
        <property type="entry name" value="SSF53790"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00096">
        <property type="entry name" value="TIGR00096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TP_methylase" evidence="7">
        <location>
            <begin position="6"/>
            <end position="207"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01877"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL70160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="230" mass="25288" checksum="77937CC4CC87189B" modified="2016-01-20" version="1">MAGIGKLYIIATPIGNLKDITLRALETLRTVDFIVCEEIRQGSKLLNRLDVQPKQLLNVNEHNEASQVDDVLQLLYAGKDGALISDCGTPVFSDPGAFLIERAVQSGITIVPIPGPSSLMAALSVLNFKPEQFHFAGFLPRDNQERKTQLNQLKSINIPIILMDTPYRLIKLLEETSAAFGPGRQATLACDISLASEKIYRGTLGEIKKEVGEKKAEFILILHAPKPSRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZ70</accession>
    <name>A0A0P6WZ70_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">HTH gntR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ADN00_16090</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16090"/>
    <dbReference type="EnsemblBacteria" id="KPL72013">
        <property type="protein sequence ID" value="KPL72013"/>
        <property type="gene ID" value="ADN00_16090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000062">
        <property type="term" value="F:fatty-acyl-CoA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019217">
        <property type="term" value="P:regulation of fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07377">
        <property type="entry name" value="WHTH_GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.530">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014178">
        <property type="entry name" value="FA-response_TF_FadR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028374">
        <property type="entry name" value="FadR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011711">
        <property type="entry name" value="GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008920">
        <property type="entry name" value="TF_FadR/GntR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000524">
        <property type="entry name" value="Tscrpt_reg_HTH_GntR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43537:SF10">
        <property type="entry name" value="PTHR43537:SF10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07840">
        <property type="entry name" value="FadR_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00392">
        <property type="entry name" value="GntR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00035">
        <property type="entry name" value="HTHGNTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00895">
        <property type="entry name" value="FCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00345">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48008">
        <property type="entry name" value="SSF48008"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50949">
        <property type="entry name" value="HTH_GNTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0010">Activator</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="5" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0678">Repressor</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="4" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH gntR-type" evidence="9">
        <location>
            <begin position="17"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL72013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="244" mass="27919" checksum="E733889CE142714D" modified="2016-01-20" version="1">MTSYQSGDRMQQWQPPQKPAELTEARLIQAILDDVFPINSNLPSERVLAVQLGTTRPTLREALQRLSRDGWLEIRHGKPTRVRDYWQEGNLSVLAAVAGHSEHLPQHFVRDLLQVRILLAPTYIRLAIEREPVQVESLLTEILVTIQDAPSFTRADWQLHFQCTRFSGNPVFTLILNGFKDLYALVGEVYFSNPEACAVSRNFYTQLLACARSQLPQEAETLTRQVMEQSLRFWLDTERAASNS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-08-12" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZA4</accession>
    <name>A0A0P6WZA4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ABC transmembrane type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_16325</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72117">
        <property type="protein sequence ID" value="KPL72117"/>
        <property type="gene ID" value="ADN00_16325"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="69"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="103"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="241"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="265"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="66"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL72117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="297" mass="32549" checksum="351892530DCAD290" modified="2016-01-20" version="1">MLPYLLLLPGLLFYFVIALGPSLATTVFSFTDATGIKGSKVNWVGLDNYKEFLFMGQASIDNLEAVGRTLIFCLLVTSIQFSLGLLVAIILNQKIKGRIIFRTIYFMPVILGAVIQGLIWSLFLFPLGGPMAKFIGLFGLRSEFLGGPPEVAFGWVTAIQIWANMGTTMIIFLAGLQTIPAEMYEAAEIDGASPWQVFTNVTWPLLTPSVNTNLTLNIIGSLQAWQLFLILIGYRNKTQVLGYLIYAVGFGQTSGSVTASFRQGYAAAASIVLFVIVLVLGMSANYFLQRRETRILG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X125</accession>
    <name>A0A0P6X125_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">ADN00_11765</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063211.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11765"/>
    <dbReference type="EnsemblBacteria" id="KPL76031">
        <property type="protein sequence ID" value="KPL76031"/>
        <property type="gene ID" value="ADN00_11765"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043772">
        <property type="term" value="F:acyl-phosphate glycerol-3-phosphate acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003811">
        <property type="entry name" value="G3P_acylTferase_PlsY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30309">
        <property type="entry name" value="PTHR30309"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02660">
        <property type="entry name" value="G3P_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01207">
        <property type="entry name" value="G3P_acyltransf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="2" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0594">Phospholipid biosynthesis</keyword>
    <keyword evidence="9" id="KW-1208">Phospholipid metabolism</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="97"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="127"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="156"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="179"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL76031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="237" mass="26124" checksum="5A33165CD9E6767F" modified="2016-01-20" version="1">MNLFVLSTVCVVSYLLGAISFSRIAAKKYAPEENWVDSRVVASTTREEFTLTGISATTIGNRLGEKAGCLVGILDMSKAFVPALALRLLFPEQPYHLAAAVMAMVGHNWPVYYGFKGGHGYSTVYGGLLAIDPIGAIVSSVVGMALGLFVVRDFMVAYLSGMWLLIPWMWLRWQDPLMVAYALAVNVIFMLAMIPEIKQVKSGLEKHGKSDLRTSMQDWPMGRGILKMADKLNIRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X2G9</accession>
    <name>A0A0P6X2G9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_14715</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000035">
        <property type="protein sequence ID" value="KPL73589.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063790.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000035.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14715"/>
    <dbReference type="EnsemblBacteria" id="KPL73589">
        <property type="protein sequence ID" value="KPL73589"/>
        <property type="gene ID" value="ADN00_14715"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="SSF54106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="SSF55797"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132788" description="LysM domain-containing protein" evidence="3">
        <location>
            <begin position="33"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="313"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="4">
        <location>
            <begin position="205"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="257"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="262"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL73589.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="339" mass="35099" checksum="E74A8DFD612AE22A" modified="2016-01-20" version="1">MHRTSHLRTIFSLLTALCLLGAFLLNTAPARAETPSPYDLIAAVNAWRASAGLPALNPDGALMAAAQAHSEYQASIGSWSHAGAGGTYEWDRAAAAGYGGGAAIKCDEAVAIASPSNGIDYVVYTLWNDYDHRDLVLLNPNYTDVGAGAVEKDGLIYYTLDACYTGSGGNYVPPSSSSASAGTPVPTRPAIVAIQTSTPNADGSVVHKVQFGQTMWGIAIEYGMKITEIAGLNNLDPTSPVIWPGDDLLIRPPATATVTPTPTVTTPPPTHTPKPTITPTPTRPTATPTLSPTPTRQPLLGGLPTFQPSNGRAMGIVMIVICGLGLAAVGIGSLRSKNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X2N6</accession>
    <name>A0A0P6X2N6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_10160</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76945.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062890.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10160"/>
    <dbReference type="EnsemblBacteria" id="KPL76945">
        <property type="protein sequence ID" value="KPL76945"/>
        <property type="gene ID" value="ADN00_10160"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2496"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76945.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="84" mass="9694" checksum="6CB704DD2C567834" modified="2016-01-20" version="1">MDHLPSLPKRPRHPMPAFVAQALAERGLQAAYQQRPPYQQNDYIGWILQAKREKTRQKRLLQMLDELEKGGVYMGMPHAPSQKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X320</accession>
    <name>A0A0P6X320_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MFS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_14130</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063674.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000033.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14130"/>
    <dbReference type="EnsemblBacteria" id="KPL74134">
        <property type="protein sequence ID" value="KPL74134"/>
        <property type="gene ID" value="ADN00_14130"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1926"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="41"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="75"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="98"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="133"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="161"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="201"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="272"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="296"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="331"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="361"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="8"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL74134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="396" mass="40918" checksum="1681F7774A83FD51" modified="2016-01-20" version="1">MQSANSKIILIISCVIFFALGSLTAVNGPLLAEFAQLNQTTLTEIGVIFTALFAGALISQLAAGPLSDRVGQKPVLIVGVALMVIGIVSYTFTRVYLLTLFFALLAGFGHGAVDLGGNVLIARVFKNRSVSALNLLNLFFGLGAFVGPALVSFALKTWQTGLPAVWISAGMLAVSGVWMLRTRVDEEAPTAQPGSAPAASVYRSPLLWLFGMVLLIYVGTENGIGGWATIYFEQSAAMQTAQAALVTSGFWLALTAGRLVSAGLGMRLSPAAVLVSSLVEAAAGAILLAVSHGQAALSVVAVLMIGFGFGAVYPTMIGITTETFSQGPGKAASVAAAMGSVGGMLIPWLQGVVIEQTSTRVFTFAVGALIVLMLAIAFSVTRRSAPPAAIPARPRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X4K3</accession>
    <name>A0A0P6X4K3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L28</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpmB</name>
        <name evidence="5" type="ORF">ADN00_13760</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL28 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063600.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000032.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13760"/>
    <dbReference type="EnsemblBacteria" id="KPL74357">
        <property type="protein sequence ID" value="KPL74357"/>
        <property type="gene ID" value="ADN00_13760"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.170.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00373">
        <property type="entry name" value="Ribosomal_L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034704">
        <property type="entry name" value="L28p-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026569">
        <property type="entry name" value="Ribo_L28/L24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037147">
        <property type="entry name" value="Ribo_L28/L24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001383">
        <property type="entry name" value="Ribosomal_L28"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00830">
        <property type="entry name" value="Ribosomal_L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143800">
        <property type="entry name" value="SSF143800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00009">
        <property type="entry name" value="L28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00373"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL74357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="60" mass="6747" checksum="D659615183EB11DC" modified="2016-01-20" version="1">MAKCEVCGKATTFGHNRSFSMRATNRTFRPNLQRVTVVENGRKVKKVLCAKCIRTMAKTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5B9</accession>
    <name>A0A0P6X5B9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">HTH merR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_10875</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063022.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10875"/>
    <dbReference type="EnsemblBacteria" id="KPL77052">
        <property type="protein sequence ID" value="KPL77052"/>
        <property type="gene ID" value="ADN00_10875"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.490.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000551">
        <property type="entry name" value="MerR-type_HTH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036244">
        <property type="entry name" value="TipA-like_antibiotic-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012925">
        <property type="entry name" value="TipAS_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13411">
        <property type="entry name" value="MerR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07739">
        <property type="entry name" value="TipAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00040">
        <property type="entry name" value="HTHMERR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00422">
        <property type="entry name" value="HTH_MERR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89082">
        <property type="entry name" value="SSF89082"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50937">
        <property type="entry name" value="HTH_MERR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0010">Activator</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH merR-type" evidence="6">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="77"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023159"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50937"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL77052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="252" mass="29466" checksum="26238D5BA545BCC8" modified="2016-01-20" version="1">MPYTVKQLSKMAGVSARTLHYYDEIGLLAPPEYGGNGYRHYDEASLLRLQQILFYKELGLDLKQIKAILDRPDFNVLDSLKDHRQSLHKQVKRLNLLIQTVENTIQYLEGNTTMSQKKLFEGFSEEEEKQYEAEARQLYDPQVVDESWKRWKSMSKEQKQALGQRGEEIFAGVFDCMQQGYGPESAEVQRWMPALHDHFNVFYTCTLEIFRGLGDLYVNDPKFRATFTKIHPDLPEFLQEAMAFYVDQQMAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5C3</accession>
    <name>A0A0P6X5C3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Terminase_6C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_18860</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064591.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18860"/>
    <dbReference type="EnsemblBacteria" id="KPL70104">
        <property type="protein sequence ID" value="KPL70104"/>
        <property type="gene ID" value="ADN00_18860"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3084"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006517">
        <property type="entry name" value="Arc_phage_PsiM2_terminase_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035421">
        <property type="entry name" value="Terminase_6C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17289">
        <property type="entry name" value="Terminase_6C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01630">
        <property type="entry name" value="psiM2_ORF9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Terminase_6C" evidence="1">
        <location>
            <begin position="300"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF17289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="470" mass="53281" checksum="F2A6ECBB5CD20E94" modified="2016-01-20" version="1">MVEMMNQIRIEIRPQPGPQEMFLSSPADITIYGGSAGGGKTWGLLIEAARHHRRQGYGAVIFRRTYPEITNEGGLWDESEKIYPLLGAKPVKGDLYWKFPNGSKISFGHLQFEKDLMNYQGSQIALIGYDQLEHFTQKMFFYMLSRNRSVCGVRPYIRATCNPDPDSFLANFLSWWIAEDGYADLSRAGKIRWFIQPDGQMVVWGDSREELIENYGDDVDPLSVTFIPASVFNNKILLAKDPGYLAKLKALSYIDRERLLGDPMRGGNWKVKPTAGKFFNRTWFKLVKEVPAGGIVVRRWDFAATAKELVNDDPDYTASCLMLRSQDGSFYILDVTAAQMGPAEVDKYFMNLTRQDAVRFREEKRQYLSRWEQEPGSAGKRESFRLTKLLVGIDAHGIPSTGDKLVRAKPLAAQAEAGNVYLLEGPWNEMFLSHMHGQPDLPHDDIMDSTSGAFDDLSRPILRIARSYQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5D6</accession>
    <name>A0A0P6X5D6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Polyphosphate kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_07275</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062318.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07275"/>
    <dbReference type="EnsemblBacteria" id="KPL78262">
        <property type="protein sequence ID" value="KPL78262"/>
        <property type="gene ID" value="ADN00_07275"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3275"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008976">
        <property type="term" value="F:polyphosphate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006797">
        <property type="term" value="P:polyphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016898">
        <property type="entry name" value="Polyphosphate_phosphotransfera"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022300">
        <property type="entry name" value="PPK2-rel_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022488">
        <property type="entry name" value="PPK2-related"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03976">
        <property type="entry name" value="PPK2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028756">
        <property type="entry name" value="PPK2_prd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03709">
        <property type="entry name" value="PPK2_rel_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PPK2" evidence="3">
        <location>
            <begin position="30"/>
            <end position="250"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL78262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="268" mass="31232" checksum="ED03C64BBF0BB1FA" modified="2016-01-20" version="1">MPTFNPVKPGEKIDLSKLDPADSSFFEEGKKEGKKQLTKLTEKLEILQELFYAHGKHRLLIVLQAMDTGGKDGVIRHVFEGVNPQGVSVANFKVPTPEELSHDYLWRIHKQTPSAGEIVIFNRSHYEDVLVVRVKNMVDKHVWSRRFDQINAFEKMLSEEGTIILKFFLHISKDEQKQRLQERLDDPSKHWKFNPGDLKDRALWDEYMHAYEDVLSRTSTAWAPWYIIPSDRKWLRSLIIADILVKTLEGLNMTLPDRTEELSHITIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X6M9</accession>
    <name>A0A0P6X6M9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transketolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05605</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061989.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05605"/>
    <dbReference type="EnsemblBacteria" id="KPL78719">
        <property type="protein sequence ID" value="KPL78719"/>
        <property type="gene ID" value="ADN00_05605"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1598"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd02012">
        <property type="entry name" value="TPP_TK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005474">
        <property type="entry name" value="Transketolase_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00456">
        <property type="entry name" value="Transketolase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TRANSKETOLASE_1" evidence="1">
        <location>
            <begin position="14"/>
            <end position="253"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00456"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="276" mass="30270" checksum="481E5E647234B454" modified="2016-01-20" version="1">MDVKTLIQKSIQYRKRTLKAIKTANAGHTGGDLSCLDILNVLYNHVMNISPDNMQSPDRDRFIQSKGHSVEALYVVLSDKGFFPDSALDTICQYQSDFIGHPTRKIPGVEQNTGALGHGLSVAVGLALAAKMDERAYRVFTLMGDGELTEGSLWEASMSAAHYKLDNLVVIVDRNGLQITGKTEEVMALEPLGQKFEAFGYAVKTVDGNDIPALLNMFSQLPFEPGKPSLILASTVKGKGISFMEHKADWHHHVPTDEEMLIALRELDAALETQVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X6R0</accession>
    <name>A0A0P6X6R0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_11585</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL75999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL75999">
        <property type="protein sequence ID" value="KPL75999"/>
        <property type="gene ID" value="ADN00_11585"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3792"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031621">
        <property type="entry name" value="HisKA_7TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16927">
        <property type="entry name" value="HisKA_7TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="137"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="2">
        <location>
            <begin position="236"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="3">
        <location>
            <begin position="375"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL75999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="524" mass="58224" checksum="78FDBF82B98D5F0C" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X782</accession>
    <name>A0A0P6X782_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 7" type="primary">rplB</name>
        <name evidence="7" type="ORF">ADN00_12585</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">One of the primary rRNA binding proteins. Required for association of the 30S and 50S subunits to form the 70S ribosome, for tRNA binding and peptide bond formation. It has been suggested to have peptidyltransferase activity; this is somewhat controversial. Makes several contacts with the 16S rRNA in the 70S ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 50S ribosomal subunit. Forms a bridge to the 30S subunit in the 70S ribosome.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uL2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76164.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063367.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12585"/>
    <dbReference type="EnsemblBacteria" id="KPL76164">
        <property type="protein sequence ID" value="KPL76164"/>
        <property type="gene ID" value="ADN00_12585"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3998"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01320_B">
        <property type="entry name" value="Ribosomal_L2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022666">
        <property type="entry name" value="Rbsml_prot_L2_RNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014722">
        <property type="entry name" value="Rib_L2_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002171">
        <property type="entry name" value="Ribosomal_L2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005880">
        <property type="entry name" value="Ribosomal_L2_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022669">
        <property type="entry name" value="Ribosomal_L2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014726">
        <property type="entry name" value="Ribosomal_L2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008991">
        <property type="entry name" value="Translation_prot_SH3-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13691">
        <property type="entry name" value="PTHR13691"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00181">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03947">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002158">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01383">
        <property type="entry name" value="Ribosomal_L2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01382">
        <property type="entry name" value="Ribosomal_L2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50104">
        <property type="entry name" value="SSF50104"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01171">
        <property type="entry name" value="rplB_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4" id="KW-0699">rRNA-binding</keyword>
    <feature type="domain" description="Ribosomal_L2_C" evidence="6">
        <location>
            <begin position="124"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="221"/>
            <end position="274"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01320"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM01382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL76164.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="274" mass="30177" checksum="9B658A6FDE53396E" modified="2016-01-20" version="1">MAVKIYKPITPGTRHRTGYTFEEITKSTPERSLVVPRKKNAGRNMYGRVTVRHQGGGHRQKIRLVDFKRDKVNVPATVASIEYDPNRTARLALLHYVDGEKRYILAPVGLKVGDKVVNGPEAEIRPGNALPIANIPVGTMIHNVELKEGKGGQMVRSAGAAAQLLAKEGDYATVRLPSGEMRLVRQGCYATIGQVGNLDHSNVKLGKAGRKRHLGIRPSVRGTAMTPRDHPHGGGEGRQPIGMPGPKTPWGRPALGYKTRRNKKTDQYIVRRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7E1</accession>
    <name>A0A0P6X7E1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">L-seryl-tRNA(Sec) selenium transferase</fullName>
            <ecNumber evidence="5">2.9.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Selenocysteine synthase</fullName>
            <shortName evidence="5">Sec synthase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Selenocysteinyl-tRNA(Sec) synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">selA</name>
        <name evidence="8" type="ORF">ADN00_18660</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Converts seryl-tRNA(Sec) to selenocysteinyl-tRNA(Sec) required for selenoprotein biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>H(+) + L-seryl-tRNA(Sec) + selenophosphate = L-selenocysteinyl-tRNA(Sec) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:22728"/>
            <dbReference type="Rhea" id="RHEA-COMP:9742"/>
            <dbReference type="Rhea" id="RHEA-COMP:9743"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16144"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:78533"/>
            <dbReference type="ChEBI" id="CHEBI:78573"/>
            <dbReference type="EC" id="2.9.1.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 5 6">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Aminoacyl-tRNA biosynthesis; selenocysteinyl-tRNA(Sec) biosynthesis; selenocysteinyl-tRNA(Sec) from L-seryl-tRNA(Sec) (bacterial route): step 1/1.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the SelA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.9.1.1" evidence="5"/>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064552.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18660"/>
    <dbReference type="EnsemblBacteria" id="KPL70071">
        <property type="protein sequence ID" value="KPL70071"/>
        <property type="gene ID" value="ADN00_18660"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3041"/>
    <dbReference type="UniPathway" id="UPA00906">
        <property type="reaction ID" value="UER00896"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004125">
        <property type="term" value="F:L-seryl-tRNASec selenium transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001514">
        <property type="term" value="P:selenocysteine incorporation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097056">
        <property type="term" value="P:selenocysteinyl-tRNA(Sec) biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00423">
        <property type="entry name" value="SelA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018319">
        <property type="entry name" value="SelA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004534">
        <property type="entry name" value="SelA_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025862">
        <property type="entry name" value="SelA_trans_N_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12390">
        <property type="entry name" value="Se-cys_synth_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03841">
        <property type="entry name" value="SelA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00474">
        <property type="entry name" value="selA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="5 6" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0711">Selenium</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Se-cys_synth_N" evidence="7">
        <location>
            <begin position="5"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="5 6">
        <location>
            <position position="291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR618319-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF12390"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL70071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="464" mass="49679" checksum="84D69D62E5B89CDE" modified="2016-01-20" version="1">MTNPRDLPAVDSLLQHKQAAELVAEYGRGQTLNAIREELAALRESMLAGEEITLPKNGGILEAAKKRLQKQFQPTLEAVINATGVVLHTNLGRAPLSTVDMQQLAVLLSSYNTLEFDLESGKRGSRSVHAEALIRRLTGAEAALVVNNNAAAVLLALSALSKGKRAIISRSQLVEIGGGFRVPDVMRQSGAKLVEIGTTNRVNLQDYEEALEEPSALVVRAHHSNFKLVGFTHEPDFAAIVKAAHARGVPVLDDLGSGALLDTSRYGLAHEPMVQESLAAGADLVCFSGDKLLGGPQAGILVGKADLVAKVKRHPLARAVRADKFCLAALAVTLEHYLKEEAERAIPIWVMISAPLKQLEKRARHWQASLGAGEVVESVSTVGGGSLPEETLPTYALALRPPKLAAFQKALRQMSPPVIARVENDQVLFDPRTVLPEQEGALLVGLANALAMGAGGRFKKEEQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7F3</accession>
    <name>A0A0P6X7F3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ZnF_CHCC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_18775</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064573.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70089">
        <property type="protein sequence ID" value="KPL70089"/>
        <property type="gene ID" value="ADN00_18775"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003896">
        <property type="term" value="F:DNA primase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036977">
        <property type="entry name" value="DNA_primase_Znf_CHC2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002694">
        <property type="entry name" value="Znf_CHC2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01807">
        <property type="entry name" value="zf-CHC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ZnF_CHCC" evidence="4">
        <location>
            <begin position="15"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL70089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="81" mass="9753" checksum="41B9188B7EFF6EC8" modified="2016-01-20" version="1">MNPKEEIRKETENEVVFQLAKQINARRYLSDVFVTNCPFCKEENNWLIFNARGYHCMSCKADGEIEELIERYQKHNLNKHF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7J8</accession>
    <name>A0A0P6X7J8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">(R)-citramalate synthase</fullName>
            <ecNumber evidence="4">2.3.1.182</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">ADN00_19060</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>acetyl-CoA + H2O + pyruvate = (3R)-citramalate + CoA + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19045"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30934"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="EC" id="2.3.1.182"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-isoleucine biosynthesis; 2-oxobutanoate from pyruvate: step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 9">Belongs to the alpha-IPM synthase/homocitrate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.182" evidence="4"/>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064628.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_19060"/>
    <dbReference type="EnsemblBacteria" id="KPL70135">
        <property type="protein sequence ID" value="KPL70135"/>
        <property type="gene ID" value="ADN00_19060"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3125"/>
    <dbReference type="UniPathway" id="UPA00047">
        <property type="reaction ID" value="UER00066"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043714">
        <property type="term" value="F:(R)-citramalate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003852">
        <property type="term" value="F:2-isopropylmalate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009097">
        <property type="term" value="P:isoleucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009098">
        <property type="term" value="P:leucine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013709">
        <property type="entry name" value="2-isopropylmalate_synth_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002034">
        <property type="entry name" value="AIPM/Hcit_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005675">
        <property type="entry name" value="Citramal_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036230">
        <property type="entry name" value="LeuA_allosteric_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000891">
        <property type="entry name" value="PYR_CT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43538">
        <property type="entry name" value="PTHR43538"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00682">
        <property type="entry name" value="HMGL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08502">
        <property type="entry name" value="LeuA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00917">
        <property type="entry name" value="LeuA_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110921">
        <property type="entry name" value="SSF110921"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00977">
        <property type="entry name" value="citramal_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00815">
        <property type="entry name" value="AIPM_HOMOCIT_SYNTH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50991">
        <property type="entry name" value="PYR_CT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8" id="KW-0100">Branched-chain amino acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0412">Isoleucine biosynthesis</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 9 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate carboxyltransferase" evidence="10">
        <location>
            <begin position="2"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004743"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012337"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022624"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003523"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL70135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="517" mass="56722" checksum="5E47FF782491AA89" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7K8</accession>
    <name>A0A0P6X7K8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">ArsR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_19105</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064637.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70144">
        <property type="protein sequence ID" value="KPL70144"/>
        <property type="gene ID" value="ADN00_19105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018656">
        <property type="entry name" value="DUF2087"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001845">
        <property type="entry name" value="HTH_ArsR_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012318">
        <property type="entry name" value="HTH_CRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09860">
        <property type="entry name" value="DUF2087"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01022">
        <property type="entry name" value="HTH_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00778">
        <property type="entry name" value="HTHARSR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00418">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00419">
        <property type="entry name" value="HTH_CRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50987">
        <property type="entry name" value="HTH_ARSR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51063">
        <property type="entry name" value="HTH_CRP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH arsR-type" evidence="1">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="HTH crp-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50987"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL70144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="192" mass="21767" checksum="F297DC06E47A6C58" modified="2016-01-20" version="1">MDATQELLNFFKALADANRLKIVGLLSQQDLTVEQIAEMLALSPSTVSHHLSRLSKAGLVSARAESYYNIYHLQVNELEAMSKRLLAHEDLPEVTQEIDVDAYDHKVIKSYTNPDGTLKTIPTQLKKLDAILRYVLKGFQPGARYTEKQVNEILQHYNEDYAQLRRELVEQGYMCRQGGGGDYWLPDAPAND</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7T9</accession>
    <name>A0A0P6X7T9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">NADH dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_04300</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061725.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04300"/>
    <dbReference type="EnsemblBacteria" id="KPL79094">
        <property type="protein sequence ID" value="KPL79094"/>
        <property type="gene ID" value="ADN00_04300"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008901">
        <property type="term" value="F:ferredoxin hydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016651">
        <property type="term" value="F:oxidoreductase activity, acting on NAD(P)H"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048038">
        <property type="term" value="F:quinone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.645.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001135">
        <property type="entry name" value="NADH_Q_OxRdtase_suD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001501">
        <property type="entry name" value="Ni-dep_hyd_lsu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018194">
        <property type="entry name" value="Ni-dep_hyd_lsu_Ni_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029014">
        <property type="entry name" value="NiFe-Hase_large"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00346">
        <property type="entry name" value="Complex1_49kDa"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00374">
        <property type="entry name" value="NiFeSe_Hases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56762">
        <property type="entry name" value="SSF56762"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00507">
        <property type="entry name" value="NI_HGENASE_L_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Complex1_49kDa" evidence="4">
        <location>
            <begin position="126"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="domain" description="Complex1_49kDa" evidence="4">
        <location>
            <begin position="290"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009292"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00346"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL79094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="393" mass="44552" checksum="BF0EA02E771A4374" modified="2016-01-20" version="1">MEKQEKFIVPIGPQHPALKEPGHFEFTVDGEVVTSATARLGYVHRGIEKAVESRNWTQAMYMLERICGICSHVHATAYCLGVEQLAGVQAPPRAQAIRVLIAELERIHSHMLWWGVAAHEGGFDILFMYTWRDRETVMELLEMLSGNRVHYSANLIGGVKFDIDQKQADAIRKGIDYLEERTHHYLEIITTDETFLGRTRNIGVMSPEVAKSLGAVGPTARASNIHRDLRVDQPYAGYDMFPVKLVTETQGDLEARFVVRLKELFESYRIIREVLDNLPESELTVKVPRKIPAGQVISRVEAPRGELFYYIESNGSDQPERIKVRTPTLPNWGTVLATAVGLKLADMPMLLVGIDPCFSCNDRLVLVKDQNQTQSGKTWTWEDLRIHGIERYK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X948</accession>
    <name>A0A0P6X948_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_12395</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063329.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12395"/>
    <dbReference type="EnsemblBacteria" id="KPL76131">
        <property type="protein sequence ID" value="KPL76131"/>
        <property type="gene ID" value="ADN00_12395"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027396">
        <property type="entry name" value="DsrEFH-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003787">
        <property type="entry name" value="Sulphur_relay_DsrE/F-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02635">
        <property type="entry name" value="DrsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75169">
        <property type="entry name" value="SSF75169"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="112" mass="12094" checksum="02BF85CB36A25647" modified="2016-01-20" version="1">MKNAVIVFSRNGMGHAPVELQSKLAKKFLRLTIESGNLPGKILFYTEGVKLACSGSEALEELQELEAKGVELVLCLTCLDFFRLTDQVKVGVVGGMGDILTAIQMADHVISV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9F7</accession>
    <name>A0A0P6X9F7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Heme ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_09755</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Probably part of an ABC transporter complex. Responsible for energy coupling to the transport system.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062812.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09755"/>
    <dbReference type="EnsemblBacteria" id="KPL76877">
        <property type="protein sequence ID" value="KPL76877"/>
        <property type="gene ID" value="ADN00_09755"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2408"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03225">
        <property type="entry name" value="ABC_cobalt_CbiO_domain1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022216">
        <property type="entry name" value="ABC_Co_transporter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015856">
        <property type="entry name" value="ABC_transpr_CbiO/EcfA_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12558">
        <property type="entry name" value="DUF3744"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="7"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="303"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="41"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="336"/>
            <end position="343"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00025157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL76877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="569" mass="63248" checksum="3D7025CAAB48F53A" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XB19</accession>
    <name>A0A0P6XB19_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptide deformylase</fullName>
            <shortName evidence="2">PDF</shortName>
            <ecNumber evidence="2">3.5.1.88</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Polypeptide deformylase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">def</name>
        <name evidence="3" type="ORF">ADN00_10095</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>H2O + N-terminal N-formyl-L-methionyl-[peptide] = formate + N-terminal L-methionyl-[peptide]</text>
            <dbReference type="Rhea" id="RHEA:24420"/>
            <dbReference type="Rhea" id="RHEA-COMP:10639"/>
            <dbReference type="Rhea" id="RHEA-COMP:10640"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15740"/>
            <dbReference type="ChEBI" id="CHEBI:49298"/>
            <dbReference type="ChEBI" id="CHEBI:64731"/>
            <dbReference type="EC" id="3.5.1.88"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Fe(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29033"/>
        </cofactor>
        <text evidence="2">Binds 1 Fe(2+) ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the polypeptide deformylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.88" evidence="2"/>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062878.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10095"/>
    <dbReference type="EnsemblBacteria" id="KPL76935">
        <property type="protein sequence ID" value="KPL76935"/>
        <property type="gene ID" value="ADN00_10095"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2482"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042586">
        <property type="term" value="F:peptide deformylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00487">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.45.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00163">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023635">
        <property type="entry name" value="Peptide_deformylase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036821">
        <property type="entry name" value="Peptide_deformylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10458">
        <property type="entry name" value="PTHR10458"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01327">
        <property type="entry name" value="Pep_deformylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004749">
        <property type="entry name" value="Pep_def"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01576">
        <property type="entry name" value="PDEFORMYLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56420">
        <property type="entry name" value="SSF56420"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00079">
        <property type="entry name" value="pept_deformyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" evidence="2">
        <location>
            <position position="143"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="100"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="146"/>
        </location>
        <ligand>
            <name>Fe cation</name>
            <dbReference type="ChEBI" id="CHEBI:24875"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL76935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="184" mass="20749" checksum="9488DE2EC120E5AB" modified="2016-01-20" version="1">MAVREILIYPQSKNELRAKSQPVEKIDKSLKHLIADLKDTLQAHENGIGLASPQINVHKQVVIVCLGYEQEGEWVTGPPEALINPRVIEAGDERRDFDGCLSFPGLYGETIRPHLLRVTGLDEQGQPFDRYYEGFNAVVVHHEIDHLEGVLFIDRVQSAKDLYTLEKNTRGQTIRVPFNAKIPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBH7</accession>
    <name>A0A0P6XBH7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_08580</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000022">
        <property type="protein sequence ID" value="KPL77645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77645">
        <property type="protein sequence ID" value="KPL77645"/>
        <property type="gene ID" value="ADN00_08580"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1425"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="4"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="36"/>
            <end position="43"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL77645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="298" mass="33514" checksum="EC98639FB94E6470" modified="2016-01-20" version="1">MFVARTENLTKIYGTRAGIDSLTLEVEPGEVFGFLGPDGAGKTTTIRLFMDLIRPTSGRALLFGMDSHAQSVHIRKLVGYLPAQMSLPRFTTGANVLRYFSKLRGGVSFSKIEHLAGRLKVNLNAPIQRLDEADTFKIGLVQAFMHDPELLLLDEPTRYLDDAGREALYELIAEVRREGRTVFISSRSLNEMERITDRVGVIHNGRLVAVERAVHLRARAFNKVEMQFAGPVTHEIFESQPTIRNLRWQENRLQCLVTGDPQALLELARKQSEVMDFKARQPSLEEAFSLYYGVGHAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBK7</accession>
    <name>A0A0P6XBK7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HTH luxR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_02530</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000011">
        <property type="protein sequence ID" value="KPL79575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061386.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000011.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79575">
        <property type="protein sequence ID" value="KPL79575"/>
        <property type="gene ID" value="ADN00_02530"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041617">
        <property type="entry name" value="TPR_MalT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17874">
        <property type="entry name" value="TPR_MalT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="2">
        <location>
            <begin position="499"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="821"/>
            <end position="886"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL79575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="888" mass="99993" checksum="71215465F9820D06" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBS6</accession>
    <name>A0A0P6XBS6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Hydrogenase maturation factor HypA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">hypA</name>
        <name evidence="5" type="ORF">ADN00_15410</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the HypA/HybF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15410"/>
    <dbReference type="EnsemblBacteria" id="KPL72211">
        <property type="protein sequence ID" value="KPL72211"/>
        <property type="gene ID" value="ADN00_15410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016151">
        <property type="term" value="F:nickel cation binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051604">
        <property type="term" value="P:protein maturation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00213">
        <property type="entry name" value="HypA_HybF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000688">
        <property type="entry name" value="HypA/HybF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34535">
        <property type="entry name" value="PTHR34535"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01155">
        <property type="entry name" value="HypA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004761">
        <property type="entry name" value="Hydrgn_mat_HypA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00100">
        <property type="entry name" value="hypA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1 4" id="KW-0533">Nickel</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0862">Zinc</keyword>
    <feature type="binding site" evidence="4">
        <location>
            <position position="2"/>
        </location>
        <ligand>
            <name>Ni(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:49786"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="73"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="76"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="89"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="92"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL72211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="116" mass="13114" checksum="091B266E1344BA7A" modified="2016-01-20" version="1">MHELSVTENILQITLKHAQQAGAKSVTDVHLVIGELSSIIDDSVQFYWDMITENTICQSAQLHFTRIPAKMLCQNCKQEFTIEHGPIPCPSCGSVNLRVIQGEEFWVDSIEIQKEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBT5</accession>
    <name>A0A0P6XBT5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_15530</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063944.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72229">
        <property type="protein sequence ID" value="KPL72229"/>
        <property type="gene ID" value="ADN00_15530"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="101" mass="11250" checksum="F40F463A861208A9" modified="2016-01-20" version="1">MANSIAKEIMSKAAAKSIQLFEVKLTITSDGAVHGILTLQSGKVDTMTKLALMDIVADTFRREIDGHISFSKNSVFFWDPAKFQARFKEQGGLTTMRLQRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBV9</accession>
    <name>A0A0P6XBV9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_15725</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72265.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063982.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72265">
        <property type="protein sequence ID" value="KPL72265"/>
        <property type="gene ID" value="ADN00_15725"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72265.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="359" mass="39339" checksum="7940BC0A264EB8BE" modified="2016-01-20" version="1">MSNIFGLLNVQDYAADRTFVNQVGQQIVYDAVQQEIARIDEEINRALSVFVDERTSDFKRRYKLPGSGYMQPGTNQAPPANTKASGSWDIALPLLDFQDAVGGNRVQMAYMSVKDLNIHLDSLQIRAANSVRREILRALFNNTTWSFQDEIHGVLSVVPLANNDGTLYPAVVSSDTEAQDNHYLVSGYAASSISDTNDPIKSIVAEIYEHFGYGDNLVVFINSAQTAKVLALAMVEEVGDKFIVPGANTAQVIGLPAGLPGRIKGRHSSGAWIVEWDRVPANYMVGVHMDAPKPIIERVDPPETGLPSGLTLVARDEEFPLESAYYQMRRGFGVGNRLNGCVMFLDSGSTYTVPSAYGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDJ6</accession>
    <name>A0A0P6XDJ6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AAA_31 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_07550</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78303">
        <property type="protein sequence ID" value="KPL78303"/>
        <property type="gene ID" value="ADN00_07550"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025669">
        <property type="entry name" value="AAA_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13614">
        <property type="entry name" value="AAA_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA_31" evidence="1">
        <location>
            <begin position="10"/>
            <end position="189"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="269" mass="29164" checksum="3340EB4641D52AC7" modified="2016-01-20" version="1">MSLPTDLMTQTIAISNQKGGVGKTTTCASIGAALVKKGARVLLVDLDSQASLSVALGQAVHLNDESIADLLDTSPSSGELSPADLIHPTSLPGLDIALGDPRLAVVEHHLPEQTGYEHLLKNHLQSLAAGYDFVLQDCSPSLGPLTIMALTAANQVIVPVQPDYLAAWGIMRLMETIEAVHQRTNPHLQYRILAVMYDQRNTITREMLNRLQQNFNGRIFKTIIGVDTRVRECAVTGEPLLQYAPSTRASKQYLQAAGEYLQWIGSSEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDS4</accession>
    <name>A0A0P6XDS4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_00480</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00480"/>
    <dbReference type="EnsemblBacteria" id="KPL81047">
        <property type="protein sequence ID" value="KPL81047"/>
        <property type="gene ID" value="ADN00_00480"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL81047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="375" mass="41811" checksum="056E23A9DF497368" modified="2016-01-20" version="1">MRIFQLLRHLNILGHVIDLVSFHQADQGTNVETVQYCRDSFAFLYDSFQPARFESLLGYLSPKPRSLVGTHSPQLFKKVEELSSRERYDMAILSQIDMLPYRKAIGNIPCFLEEIEIGVYVDRFEKQRGLKSARGKLTFSKLASYLRKESKDLVGMSVVSEQERDLVLRWVKPSCPIEVIQNGVDTDGNQPFVGKFEIEPLSMVFAGSLTYSANLEAMAFFTHRVLPIILDKFPSAKLYITGKYQGCDLNQLNLCPSVVLTGYLSDVRPRVASSVVSVAPLFSGGGTRLKILESLSLGTPVVSTEKGAEGLASLAESGVVIANEPTKIADQIARLFIDPAWRAALSKSGKMSVESQYSWNQTLRPFSRLVSKINR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XE13</accession>
    <name>A0A0P6XE13_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 11">Pyruvate kinase</fullName>
            <ecNumber evidence="3 11">2.7.1.40</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">ADN00_15020</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>ATP + pyruvate = ADP + H(+) + phosphoenolpyruvate</text>
            <dbReference type="Rhea" id="RHEA:18157"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.40"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 11">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the pyruvate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.40" evidence="3 11"/>
    <dbReference type="EMBL" id="LGCL01000036">
        <property type="protein sequence ID" value="KPL73097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063850.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000036.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15020"/>
    <dbReference type="EnsemblBacteria" id="KPL73097">
        <property type="protein sequence ID" value="KPL73097"/>
        <property type="gene ID" value="ADN00_15020"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1868"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00188"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030955">
        <property type="term" value="F:potassium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004743">
        <property type="term" value="F:pyruvate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.33.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1380.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001697">
        <property type="entry name" value="Pyr_Knase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015793">
        <property type="entry name" value="Pyrv_Knase_brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015795">
        <property type="entry name" value="Pyrv_Knase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036918">
        <property type="entry name" value="Pyrv_Knase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015806">
        <property type="entry name" value="Pyrv_Knase_insert_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11817">
        <property type="entry name" value="PTHR11817"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00224">
        <property type="entry name" value="PK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02887">
        <property type="entry name" value="PK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01050">
        <property type="entry name" value="PYRUVTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="SSF50800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52935">
        <property type="entry name" value="SSF52935"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01064">
        <property type="entry name" value="pyruv_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="6 11" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PK" evidence="12">
        <location>
            <begin position="5"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="domain" description="PK_C" evidence="13">
        <location>
            <begin position="369"/>
            <end position="477"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF00224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KPL73097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="487" mass="53313" checksum="35A3186BA4697DA7" modified="2016-01-20" version="1">MKTGKRTKIVATIGPASEDPATIMAMIRAGMDVARLNFSHGDHAEHQKRIATIRSLSNRLEKPVSILQDLQGPKLRVGDLPKEGLLLEPHQKVYLASTEDTQVSELPPDITHFIPLDVPDLKNQLKAGDHIMLNDGYQELEVVEVGDGFIEASVVQGGKLTSHKGVNFPGVNLNIPAFTEKDREDLQFGLSQGVDAIAMSFVRTAKDIETVRKAMQEFDPQRADTPIIAKLERPEAIQNLSEILRVADGVMVARGDLAVETSPAIVPVMQKKIITEANKHNRLVITATQMLESMIQNPRPTRAEASDVANAIFDGTDAVMLSGETAMGSFPIRSVEMMTSIIETAEENFSQWGQIPAWYEEPTDSDAIATTRAANELARDRNVACIAVFTLTGHSAMLISKTRPHVPVVALTPVMETYQRMSMYWGITPFLVPYTYTVETMVTQVDAILVSNKIVKPCDQAVIITGLPVGAMRPPNLALLHTVGEPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XF19</accession>
    <name>A0A0P6XF19_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_07075</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CDP-alcohol phosphatidyltransferase class-I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78233.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07075"/>
    <dbReference type="EnsemblBacteria" id="KPL78233">
        <property type="protein sequence ID" value="KPL78233"/>
        <property type="gene ID" value="ADN00_07075"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3233"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016780">
        <property type="term" value="F:phosphotransferase activity, for other substituted phosphate groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1760">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000462">
        <property type="entry name" value="CDP-OH_P_trans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043130">
        <property type="entry name" value="CDP-OH_PTrfase_TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01066">
        <property type="entry name" value="CDP-OH_P_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00379">
        <property type="entry name" value="CDP_ALCOHOL_P_TRANSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="144"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003750"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78233.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="188" mass="20409" checksum="09A19B0E95D3F4CA" modified="2016-01-20" version="1">MFKNVIDPIAAFLNRLGLKPNTVTLSGLIGHTAAAYLIAQGEVTWGGLLILVMAPVDALDGAMARLRGEPSKFGAFIDSVTDRYSELVLFGGLLVYFLNQNNWLGCGLVYLAAAGSVMVSYTRARAETLGFDGKIGLLSRVERYIILIPSLIFNLSIYGLGIIAVLANFTAVQRIWSVRKQAHETMNL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XFX9</accession>
    <name>A0A0P6XFX9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_14035</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063656.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000033.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14035"/>
    <dbReference type="EnsemblBacteria" id="KPL74118">
        <property type="protein sequence ID" value="KPL74118"/>
        <property type="gene ID" value="ADN00_14035"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1907"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01949">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000160">
        <property type="entry name" value="GGDEF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00990">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00267">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="SSF55073"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00254">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50887">
        <property type="entry name" value="GGDEF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAC" evidence="3">
        <location>
            <begin position="200"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="2">
        <location>
            <begin position="252"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="3">
        <location>
            <begin position="325"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="domain" description="GGDEF" evidence="4">
        <location>
            <begin position="586"/>
            <end position="720"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="368"/>
            <end position="399"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL74118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="723" mass="83094" checksum="52A8A380361A4EC6" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XFZ7</accession>
    <name>A0A0P6XFZ7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Bmp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_04400</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BMP lipoprotein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061740.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79108">
        <property type="protein sequence ID" value="KPL79108"/>
        <property type="gene ID" value="ADN00_04400"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003760">
        <property type="entry name" value="PnrA-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02608">
        <property type="entry name" value="Bmp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133037" description="Bmp domain-containing protein" evidence="3">
        <location>
            <begin position="25"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="domain" description="Bmp" evidence="4">
        <location>
            <begin position="46"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF02608"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL79108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="347" mass="37395" checksum="F8195799D052EB2F" modified="2016-01-20" version="1">MNQNKWVDLLVLLTLFTLVVSACAAPQPPAAKTPAAPLSGLSGMKMAAVLSGPVNDAGWNANAYQALTEARDKYGLEIAYTEYVKVEDAAQVMRDYADAGFQIIMAHGNEYSDQISEVAREYPDLHFIQTNGSEAGIPNLYTVGFAIGEGGYLMGWLACKISQTGKVAFIIGEQYPAVQYQAQMVGQACADLGLQAKVLETYVGSWTDPTKTKELTKAALEQGVDVIILMADSGDSGAIEAVREAYAAGSTSLRIISWVKDKNHLAPEFVLGGWTEDVSREIDATLQLIAAGEPGGHFAFGLAEGVVYPNPMYGLVPAEVESEFNQLLQDYLQDPSIFPNLVVRRDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XG00</accession>
    <name>A0A0P6XG00_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_14195</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063685.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000033.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74145">
        <property type="protein sequence ID" value="KPL74145"/>
        <property type="gene ID" value="ADN00_14195"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="237"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="301" mass="32196" checksum="3B5C216C153A2E70" modified="2016-01-20" version="1">MKRFFYRIAALLMMVSAILGWVISATGIYLVWRVEPHVSNGLVTAATSLDETLAATEGLLKVADSSLEQAEKSIQLVETTVDTLAGTLESTSEVTSAVADVVGDTLGDMVKGTRAALNTMTKTARLIDDTLGFVASVPFIGRSYKPEVPLSDSVSDVSASMNDLPTALGQMSVDMQTTSGSLVQLSKDTRKLATSLADIQDNLAETREVVESYQTTVTDVRGSLAVAIQNLPTWVKIAAVSITLLLVWVFLAQVAIFIYGRELFKTPRVVTVEAAPVVVEESAVEAIIESETSAEESAEEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XG10</accession>
    <name>A0A0P6XG10_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Dihydroxyacetone kinase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_04505</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061762.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04505"/>
    <dbReference type="EnsemblBacteria" id="KPL79126">
        <property type="protein sequence ID" value="KPL79126"/>
        <property type="gene ID" value="ADN00_04505"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.258"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004371">
        <property type="term" value="F:glycerone kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006071">
        <property type="term" value="P:glycerol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.340">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012737">
        <property type="entry name" value="DhaK_L_YcgS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004007">
        <property type="entry name" value="DhaL_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036117">
        <property type="entry name" value="DhaL_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02734">
        <property type="entry name" value="Dak2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01120">
        <property type="entry name" value="Dak2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101473">
        <property type="entry name" value="SSF101473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02365">
        <property type="entry name" value="dha_L_ycgS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51480">
        <property type="entry name" value="DHAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="DhaL" evidence="1">
        <location>
            <begin position="6"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="213" mass="22453" checksum="46E15C76BC4FD99F" modified="2016-01-20" version="1">MAITRDQVLAWLKAFIQVIADNKDYLTELDSAIGDADHGANMHRGFQAVLAKMPGMEDADIGTIFKQTGMTLLSTVGGAGGPLYATFFIQAGSKLAGKMEIELEDWADALEAATAGIVNRGKASLGDKTMIDALSPAVDALKQSVAEKVSLSEGLKRSTTAAEEGMKATIPLVARKGRASYLGERSAGHQDPGATSSFLLLETAMKTWSNSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XIE0</accession>
    <name>A0A0P6XIE0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">50S ribosomal protein L33</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpmG</name>
        <name evidence="5" type="ORF">ADN00_17665</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the bacterial ribosomal protein bL33 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000043">
        <property type="protein sequence ID" value="KPL70877.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064378.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000043.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17665"/>
    <dbReference type="EnsemblBacteria" id="KPL70877">
        <property type="protein sequence ID" value="KPL70877"/>
        <property type="gene ID" value="ADN00_17665"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2124"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.28.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00294">
        <property type="entry name" value="Ribosomal_L33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038584">
        <property type="entry name" value="L33_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001705">
        <property type="entry name" value="Ribosomal_L33"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018264">
        <property type="entry name" value="Ribosomal_L33_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011332">
        <property type="entry name" value="Ribosomal_zn-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43168">
        <property type="entry name" value="PTHR43168"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00471">
        <property type="entry name" value="Ribosomal_L33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57829">
        <property type="entry name" value="SSF57829"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01023">
        <property type="entry name" value="rpmG_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00582">
        <property type="entry name" value="RIBOSOMAL_L33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL70877.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="56" mass="6710" checksum="B9D306C42EBAB008" modified="2016-01-20" version="1">MASKKKDIRPVITLACTECKERNYTTEKNRRNDPGRMELKKYCSRCKKHTPHRETK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XIE5</accession>
    <name>A0A0P6XIE5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_02300</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000010">
        <property type="protein sequence ID" value="KPL79651.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061345.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000010.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02300"/>
    <dbReference type="EnsemblBacteria" id="KPL79651">
        <property type="protein sequence ID" value="KPL79651"/>
        <property type="gene ID" value="ADN00_02300"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006439">
        <property type="entry name" value="HAD-SF_hydro_IA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041492">
        <property type="entry name" value="HAD_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023198">
        <property type="entry name" value="PGP-like_dom2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13419">
        <property type="entry name" value="HAD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01549">
        <property type="entry name" value="HAD-SF-IA-v1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01509">
        <property type="entry name" value="HAD-SF-IA-v3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79651.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="237" mass="26511" checksum="1C14281D34897221" modified="2016-01-20" version="1">MADALIQPPGIDFSRVRALCFDVDGTLSDTDDLWAHRISTALTPVKWLAPRWDARAFARWMIIGLETPGNLLYHWMDRLHFDDELAVIYNRLAHLNRKKAPRKFWIIPQVMEMLSALRSAYPMSVVSARDQISTHAFLRQFDLLPHFQTVVTSQTCQYTKPFPDPIVHAAKAMGVHPEECLMIGDTTVDILAGKAAGAQTVGVLCGFGKEDELRRAGADLILPTTADLVPYLLQPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XIN4</accession>
    <name>A0A0P6XIN4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Transketolase_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13480</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063544.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000031.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13480"/>
    <dbReference type="EnsemblBacteria" id="KPL74844">
        <property type="protein sequence ID" value="KPL74844"/>
        <property type="gene ID" value="ADN00_13480"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033248">
        <property type="entry name" value="Transketolase_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02780">
        <property type="entry name" value="Transketolase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Transketolase_C" evidence="1">
        <location>
            <begin position="7"/>
            <end position="72"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02780"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="72" mass="7787" checksum="B3CB16A37E34D544" modified="2016-01-20" version="1">MHSIPFGKADVKRVGQNVTAIATLVMTHCALAAANDLDNQGIEVEVIDLRTFAPPDMDTISTSIRKTHKVVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XJK8</accession>
    <name>A0A0P6XJK8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11">ATP phosphoribosyltransferase</fullName>
            <shortName evidence="11">ATP-PRT</shortName>
            <shortName evidence="11">ATP-PRTase</shortName>
            <ecNumber evidence="4 11">2.4.2.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">hisG</name>
        <name evidence="14" type="ORF">ADN00_17425</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="10 11">Catalyzes the condensation of ATP and 5-phosphoribose 1-diphosphate to form N'-(5'-phosphoribosyl)-ATP (PR-ATP). Has a crucial role in the pathway because the rate of histidine biosynthesis seems to be controlled primarily by regulation of HisG enzymatic activity.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>1-(5-phospho-beta-D-ribosyl)-ATP + diphosphate = 5-phospho-alpha-D-ribose 1-diphosphate + ATP</text>
            <dbReference type="Rhea" id="RHEA:18473"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58017"/>
            <dbReference type="ChEBI" id="CHEBI:73183"/>
            <dbReference type="EC" id="2.4.2.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="activity regulation">
        <text evidence="11">Feedback inhibited by histidine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="2 11">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 1/9.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="11">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 11">Belongs to the ATP phosphoribosyltransferase family. Long subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.17" evidence="4 11"/>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064325.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17425"/>
    <dbReference type="EnsemblBacteria" id="KPL71462">
        <property type="protein sequence ID" value="KPL71462"/>
        <property type="gene ID" value="ADN00_17425"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00006"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003879">
        <property type="term" value="F:ATP phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00079">
        <property type="entry name" value="HisG_Long"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013820">
        <property type="entry name" value="ATP_PRibTrfase_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018198">
        <property type="entry name" value="ATP_PRibTrfase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001348">
        <property type="entry name" value="ATP_PRibTrfase_HisG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020621">
        <property type="entry name" value="ATP_PRibTrfase_HisG_long"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013115">
        <property type="entry name" value="HisG_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21403">
        <property type="entry name" value="PTHR21403"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01634">
        <property type="entry name" value="HisG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08029">
        <property type="entry name" value="HisG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="SSF54913"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00070">
        <property type="entry name" value="hisG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03455">
        <property type="entry name" value="HisG_C-term"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01316">
        <property type="entry name" value="ATP_P_PHORIBOSYLTR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 11" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 11" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="9 11" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HisG" evidence="12">
        <location>
            <begin position="58"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="HisG_C" evidence="13">
        <location>
            <begin position="235"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000915"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004667"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020998"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024861"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00079"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF08029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KPL71462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="337" mass="36788" checksum="12F1C7D57AF7087A" modified="2016-01-20" version="1">MPTEERALIRLSLPSKGRLAEDSFQLLEECGLKIYKPNPRQYAATIPALPGLVVLFQRPGDIVSSVRDGSVDFGITGLDVVEEFKGPNQDILILHEALQFGRCDLSLAVPESLEGVQSMLDLQVYASRLPSPLRVATKYPVLTTQFLNQYQIPHTLISAEGTLELAPTIGYADIISDLVSSGQTLRDNRLRPLPDGNILHSQAVLVANRKALQENPQALQVAHTLLEYIEAHLRAAGNLAIFANIRGESPEAIARLVSEKPTIRGLQGPTISPILSQDPTTKWFAINIIVPRAELGQAINELRSIGGSGVVVMPVTYIFEEEPPRFKAMLAALQPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XJP9</accession>
    <name>A0A0P6XJP9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_11595</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063180.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76001">
        <property type="protein sequence ID" value="KPL76001"/>
        <property type="gene ID" value="ADN00_11595"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="3">
        <location>
            <begin position="24"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="4">
        <location>
            <begin position="123"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="176"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL76001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="197" mass="22967" checksum="F6669FD741F9B27E" modified="2016-01-20" version="1">MSNLEADILRKLREGDGDAFTSVVETYQTPVYNLCYRMLGNPQEAEDAAQETFWRAYSNIKRYDEGRSFITWLLSIAAHYCIDQQRKRRLPTFSMELIPDEIVPGSTPDPENTFNKSEEERVMRRVLSTLKPTDRAAIVLRYWYEMSEEEISESLDLSVSAVKSRLFRARKQLAEEWKSEHPESANSERKCHESPAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XJS8</accession>
    <name>A0A0P6XJS8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">PMT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_12010</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063257.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76065">
        <property type="protein sequence ID" value="KPL76065"/>
        <property type="gene ID" value="ADN00_12010"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3878"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000030">
        <property type="term" value="F:mannosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006493">
        <property type="term" value="P:protein O-linked glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003342">
        <property type="entry name" value="Glyco_trans_39/83"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02366">
        <property type="entry name" value="PMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="105"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="195"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="222"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="287"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="331"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="360"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="390"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="domain" description="PMT" evidence="8">
        <location>
            <begin position="97"/>
            <end position="231"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL76065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="542" mass="60170" checksum="ED700FA91A419887" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XJX7</accession>
    <name>A0A0P6XJX7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5 7">50S ribosomal protein L3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplC</name>
        <name evidence="9" type="ORF">ADN00_12600</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5 7">One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5 7">Part of the 50S ribosomal subunit. Forms a cluster with proteins L14 and L19.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the universal ribosomal protein uL3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063369.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12600"/>
    <dbReference type="EnsemblBacteria" id="KPL76166">
        <property type="protein sequence ID" value="KPL76166"/>
        <property type="gene ID" value="ADN00_12600"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4001"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01325_B">
        <property type="entry name" value="Ribosomal_L3_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000597">
        <property type="entry name" value="Ribosomal_L3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019927">
        <property type="entry name" value="Ribosomal_L3_bac/org-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019926">
        <property type="entry name" value="Ribosomal_L3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11229">
        <property type="entry name" value="PTHR11229"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00297">
        <property type="entry name" value="Ribosomal_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03625">
        <property type="entry name" value="L3_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00474">
        <property type="entry name" value="RIBOSOMAL_L3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 7" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="112"/>
            <end position="166"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019301"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01325"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL76166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="209" mass="22404" checksum="A6255CFC59331C11" modified="2016-01-20" version="1">MFKGLIGKKIGMTQIFDENGAAVPVTLIEAGPCFVTQVRTPENDGYSAVQLGFEEVKPKRLTGGSLGHLKKNNLPPLRFLREFRAKEPGVSEGEKVSVEQFAIGEHVDVTGTSKGRGFQGGVKRYGFRGGPKTHGQSDRHRAPGSRGSGTTPGRVFKGSRGPGHMGNERVTQSHLMVALVDPERNLIGVRGAVPGPRGGLVLIKEARKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKG8</accession>
    <name>A0A0P6XKG8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_11110</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063083.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11110"/>
    <dbReference type="EnsemblBacteria" id="KPL76513">
        <property type="protein sequence ID" value="KPL76513"/>
        <property type="gene ID" value="ADN00_11110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="187"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="309" mass="34260" checksum="B185EC84EEEBCEC0" modified="2016-01-20" version="1">MENQEPQSQPIMEQVMELFYQGRRVDAQQLLARHLINAPQDAEAWFTMSKLVDDEDRRKQCLERALALQPDHAEAQWALTKMKPDQRPDEDPHQALENALRNEGAFSASAPVSMIEEETQAALPAEAGAAVPQDARRPTVEAWVYPPVKAGTFVLLGAGLLLSLGMAVAGGFLFFQQMQSGLAPGALSVLALPGGLLLAGLLLSVAALIALTRRGAKAAVFGRLNRSGKIASGQIADRWTEWEMEDVSDVYMVSYLFELQRRDGGKDAFWAKQQVSKKLWDRLPPRTPVKIRYLGDNPNVSRLEMHYKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKJ3</accession>
    <name>A0A0P6XKJ3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_16260</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064095.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72038">
        <property type="protein sequence ID" value="KPL72038"/>
        <property type="gene ID" value="ADN00_16260"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="16"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="59"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="281"/>
            <end position="308"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="311" mass="33795" checksum="135BEA4C03521C9C" modified="2016-01-20" version="1">MKEIFGTVVGESKRRLLIGCLTLLVGVPTMGCCLLVLFTVVLPGLDSSAAGGGSSSMPIWLLVIGLLLLAGLIGVPVAIAVMTILRRARTMDAIFNPLGFTGKAYMLYGRHYQGNHQDRSVDIYIYRGPTVEVRLQSSAQTRVLINPKESISTSAADAFGKSPLTTTDSGLESFAIYPEEETWTLNFLNDPGVVGSIQTLMRAGAEWAVIRRLEIQPGEVMLYLHRSHKIASSLIDPSALQIWLDSLTNLAHAAENQPAPQKVLQPQVDGTRQSRQRMSKALPYVIAFLVIGMPLFFIGIGLVAYLLVSLN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKY1</accession>
    <name>A0A0P6XKY1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Biphenyl 2,3-dioxygenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_15370</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72294.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064013.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15370"/>
    <dbReference type="EnsemblBacteria" id="KPL72294">
        <property type="protein sequence ID" value="KPL72294"/>
        <property type="gene ID" value="ADN00_15370"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.776"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051213">
        <property type="term" value="F:dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="SSF50022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rieske" evidence="4">
        <location>
            <begin position="14"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL72294.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="114" mass="12625" checksum="50C661931B3C5E27" modified="2016-01-20" version="1">MESTEFDASQYEFFPFGDAADLPPGERWFIDVEDRPVMVANLGGKYYAIADVCTHDDGPLGDGDIDGCEIICPRHGARFDLKTGEALTLPAVTRTMVYPVRERDGKLEIGILKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XLA4</accession>
    <name>A0A0P6XLA4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 3">Nucleoside diphosphate kinase</fullName>
            <shortName evidence="1">NDK</shortName>
            <shortName evidence="1">NDP kinase</shortName>
            <ecNumber evidence="1 3">2.7.4.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="1">Nucleoside-2-P kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="1" type="primary">ndk</name>
        <name evidence="5" type="ORF">ADN00_00610</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 3">
            <text>a 2'-deoxyribonucleoside 5'-diphosphate + ATP = a 2'-deoxyribonucleoside 5'-triphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:44640"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:73316"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.6"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a ribonucleoside 5'-diphosphate + ATP = a ribonucleoside 5'-triphosphate + ADP</text>
            <dbReference type="Rhea" id="RHEA:18113"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57930"/>
            <dbReference type="ChEBI" id="CHEBI:61557"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.4.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="1">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the NDK family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.4.6" evidence="1 3"/>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
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    <dbReference type="EnsemblBacteria" id="KPL81068">
        <property type="protein sequence ID" value="KPL81068"/>
        <property type="gene ID" value="ADN00_00610"/>
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    <dbReference type="PATRIC" id="fig|1134406.4.peg.3517"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="term" value="F:metal ion binding"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="F:nucleoside diphosphate kinase activity"/>
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        <property type="project" value="UniProtKB-UniRule"/>
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        <property type="term" value="P:CTP biosynthetic process"/>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="term" value="P:nucleoside diphosphate phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00451">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="NDK-like_dom"/>
    </dbReference>
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        <property type="entry name" value="NDK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001564">
        <property type="entry name" value="Nucleoside_diP_kinase"/>
    </dbReference>
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        <property type="entry name" value="Nucleoside_diP_kinase_AS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00334">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01243">
        <property type="entry name" value="NUCDPKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00562">
        <property type="entry name" value="NDK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54919">
        <property type="entry name" value="SSF54919"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00469">
        <property type="entry name" value="NDP_KINASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 3 5" id="KW-0418">Kinase</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NDK" evidence="4">
        <location>
            <begin position="1"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="active site" description="Pros-phosphohistidine intermediate" evidence="1">
        <location>
            <position position="115"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="57"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="91"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU004011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00562"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL81068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="151" mass="16552" checksum="EB9AE87A31CDB5AC" modified="2016-01-20" version="1">MEQTFVLIKPDGVQRGLMGEIISRLEKRGLKLVAAKFMRVSQELAETHYGAHKGKPFYNGLIKYITSAPVMAMIWEGPGAIALVRQTMGATNPAEADPGTIRHDLAIVTSRNLTHASDGPESAAAEIALWFSSDEVLSWDRSVEDWITGKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XLT4</accession>
    <name>A0A0P6XLT4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Divalent cation transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_08985</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77263">
        <property type="protein sequence ID" value="KPL77263"/>
        <property type="gene ID" value="ADN00_08985"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4031"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
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        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
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        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
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    </dbReference>
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        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="61"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="224"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="250"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="594"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="653"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="687"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="720"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="747"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="domain" description="Cation_ATPase_N" evidence="8">
        <location>
            <begin position="17"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL77263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="785" mass="84994" checksum="9A4A179A407BB860" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XM86</accession>
    <name>A0A0P6XM86_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_18365</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70028.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064505.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70028">
        <property type="protein sequence ID" value="KPL70028"/>
        <property type="gene ID" value="ADN00_18365"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133125" evidence="1">
        <location>
            <begin position="30"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70028.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="212" mass="21636" checksum="2CA5F4C0E41DC309" modified="2016-01-20" version="1">MELKRKITIISFCLAGLVLSSSGCSLLPAANTAAEASPTATATPQADATMTIPPTVTRAPTSTATVTPVVVSATNTPQPALTLAIENATFTLAGGSPVYTVNFARPEAGCGWLGLAGQVFDAQAVPLPNLLVVVEGYLGETPVEGLALTGSSPAYGPGGYEVVLGRLPVESSKALTVSLFDLEGNLLASRVALDTYADCGKNLILVNFEAVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XMP3</accession>
    <name>A0A0P6XMP3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10970</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76489.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063056.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76489">
        <property type="protein sequence ID" value="KPL76489"/>
        <property type="gene ID" value="ADN00_10970"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="162"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="198"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="227"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="260"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="294"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="326"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="374"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="467"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="498"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="531"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="563"/>
            <end position="581"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76489.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="700" mass="79242" checksum="09D19C5025613190" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XNS8</accession>
    <name>A0A0P6XNS8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">L-glyceraldehyde 3-phosphate reductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_07005</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the shaker potassium channel beta subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062269.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78223">
        <property type="protein sequence ID" value="KPL78223"/>
        <property type="gene ID" value="ADN00_07005"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3218"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005399">
        <property type="entry name" value="K_chnl_volt-dep_bsu_KCNAB-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023210">
        <property type="entry name" value="NADP_OxRdtase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036812">
        <property type="entry name" value="NADP_OxRdtase_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43150">
        <property type="entry name" value="PTHR43150"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00248">
        <property type="entry name" value="Aldo_ket_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51430">
        <property type="entry name" value="SSF51430"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Aldo_ket_red" evidence="2">
        <location>
            <begin position="28"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006515"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="330" mass="37199" checksum="BF9996ED16C057A5" modified="2016-01-20" version="1">MVYQPEENRYAMMEYRRCGKRGLMLPMISLGLWHNFGGVDTFENSRDMVLRAFDLGITHFDLANNYGPPPGSAEETFGIIMQKDLKPFRDELIISSKAGYRMWPGPYGEWGSRKYLVASADQSLKRMGLDYVDIFYSHRPDLDTPLEETMGALDFIVRSGRALYAGISSYSPEDTRKAAAILRDLGTPCLIHQPRYNMFDRWIEDGLTSALEEEGMGCIVFSPLAQGLLTDKYLEGIPEGSRASKPHGFLKPDQVSEQKVEKVRKLREIARARGQSTAQMAIAWTLRNPVITSALIGASRKEQIDNVVACLENIIFSKEELAAIDRILED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XNX6</accession>
    <name>A0A0P6XNX6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH tetR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_10230</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76956.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062903.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76956">
        <property type="protein sequence ID" value="KPL76956"/>
        <property type="gene ID" value="ADN00_10230"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023772">
        <property type="entry name" value="DNA-bd_HTH_TetR-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01081">
        <property type="entry name" value="HTH_TETR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="7"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL76956.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="192" mass="21851" checksum="736DA31C00D5242A" modified="2016-01-20" version="1">MPRQLSPERREKFLSAALQLFVTQGVHNTTTAEVARLAGSAAGTLFLYFPTKQSLVNELILHITRQQSAHIHALLAPGQNVRDAFFTIWSGTLRWFLQNPLAYQYVLQVRDSGIIEAAVIQESALFFDYYYTTIQQGLDEALIKPYPIDLIGEFLYQDLVAMMKILQRQPGARQQDALISQGFELFWDGIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XNY9</accession>
    <name>A0A0P6XNY9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Co-chaperonin GroES</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">10 kDa chaperonin</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="3">Chaperonin-10</fullName>
            <shortName evidence="3">Cpn10</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">groES</name>
        <name evidence="3" type="synonym">groS</name>
        <name evidence="5" type="ORF">ADN00_07635</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 4">Together with the chaperonin GroEL, plays an essential role in assisting protein folding. The GroEL-GroES system forms a nano-cage that allows encapsulation of the non-native substrate proteins and provides a physical environment optimized to promote and accelerate protein folding. GroES binds to the apical surface of the GroEL ring, thereby capping the opening of the GroEL channel.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Heptamer of 7 subunits arranged in a ring. Interacts with the chaperonin GroEL.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 3 4">Belongs to the GroES chaperonin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78315.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062385.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07635"/>
    <dbReference type="EnsemblBacteria" id="KPL78315">
        <property type="protein sequence ID" value="KPL78315"/>
        <property type="gene ID" value="ADN00_07635"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3357"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140662">
        <property type="term" value="F:ATP-dependent protein folding chaperone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00320">
        <property type="entry name" value="cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.33.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00580">
        <property type="entry name" value="CH10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020818">
        <property type="entry name" value="Chaperonin_GroES"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037124">
        <property type="entry name" value="Chaperonin_GroES_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10772">
        <property type="entry name" value="PTHR10772"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00166">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00297">
        <property type="entry name" value="CHAPERONIN10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00883">
        <property type="entry name" value="Cpn10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00580"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL78315.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="98" mass="10830" checksum="0DA6B3004D8CC862" modified="2016-01-20" version="1">MSLNLKPLGNRIVVEPLEQEEKTSAGLYLPDTAKEKPQQGVVLAVGPGDRDEKGERIPMDVKVDDIVLFAKYAGTEVKIDGKKILIMRENDLLAIVEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XP09</accession>
    <name>A0A0P6XP09_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_17995</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000044">
        <property type="protein sequence ID" value="KPL70768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17995"/>
    <dbReference type="EnsemblBacteria" id="KPL70768">
        <property type="protein sequence ID" value="KPL70768"/>
        <property type="gene ID" value="ADN00_17995"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="415" mass="47126" checksum="DD4EDE153B9D19BA" modified="2016-01-20" version="1">MQLGGLEPQDGKELLTQWLASVRRTLNISQRAEVLDKFEKSQCNPLYLKLAFEEARLWTSFQPQETLAAGVAGIIRENMIERLKDEGNHGEMLVSRALGYLAASRYGLAEDELVDLLSRDLEVYTWFFKQTYHLPSDLVQRAAEYLHDHPDVFVREREPDAEASTLAWLNELKQMDWKKGIPEPLVEFLATVLPQANGPHLPVVLWSRLSFDLAPFLTERLVDGSSLLAFYHRELRDASEAEFLSDGQAQAYHAKLADYFRFKADPDGDHSWSGDDIHGLSELPYHLTEAERWDQVYRTLIDFRFLEEKAARVGVVDSRDGQGQTVRTYTGVLRLQEDYERALAAMPGGRGSESWGDRSPLIVTARQKNAEMSVDCPVCHQTLLIKDEMLGTVITCPQQVCQARLKLNAFVIQTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XP82</accession>
    <name>A0A0P6XP82_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_06780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000018">
        <property type="protein sequence ID" value="KPL78424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062224.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000018.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06780"/>
    <dbReference type="EnsemblBacteria" id="KPL78424">
        <property type="protein sequence ID" value="KPL78424"/>
        <property type="gene ID" value="ADN00_06780"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.80.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010499">
        <property type="entry name" value="AraC_E-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029442">
        <property type="entry name" value="GyrI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011256">
        <property type="entry name" value="Reg_factor_effector_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06445">
        <property type="entry name" value="GyrI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00871">
        <property type="entry name" value="AraC_E_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55136">
        <property type="entry name" value="SSF55136"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AraC_E_bind" evidence="1">
        <location>
            <begin position="3"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="152" mass="17052" checksum="04B43B23FB96F11C" modified="2016-01-20" version="1">MNTPFEKISVPARPVLSVRKTTSVENLPAELGRAYQAVMLYLQELNEQPVGEPFAIYYNMDMQALDVEMGFPVRAGLPGRGEVQANLLPAGEIVTSVHQGPYPSMAPTYEAMTAWMQENHYQPSGVVGEFYLNDPEEVKPEEVLTRIEFYLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XP90</accession>
    <name>A0A0P6XP90_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Nitroreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_09825</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063034.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09825"/>
    <dbReference type="EnsemblBacteria" id="KPL77065">
        <property type="protein sequence ID" value="KPL77065"/>
        <property type="gene ID" value="ADN00_09825"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2423"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.109.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029479">
        <property type="entry name" value="Nitroreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000415">
        <property type="entry name" value="Nitroreductase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00881">
        <property type="entry name" value="Nitroreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55469">
        <property type="entry name" value="SSF55469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="domain" description="Nitroreductase" evidence="2">
        <location>
            <begin position="30"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="221" mass="24751" checksum="20FF9D0012596244" modified="2016-01-20" version="1">MTQETFEPLAFQEKPVDEMIAASRAFDAEMRRRHSVREFSSHPIPMEVIENAIRAAGSAPSGANMQPWHFAVVTSAEKKRQIRAAAEREERAFYEKRASAEWLDALAPLNTNASKPFLETAPCLIAIFYKSTTLTGQGKTRKNYYPKESVGIATGILITALHLAGLVTLTYTPSPMNFLNDLLQRPKNEHPFLLLVTGYPAENAQVPQLEKYPLEKIATFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XPS7</accession>
    <name>A0A0P6XPS7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex</fullName>
            <ecNumber evidence="5">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_05360</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>(R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + acetyl-CoA = (R)-N(6)-(S(8)-acetyldihydrolipoyl)-L-lysyl-[protein] + CoA</text>
            <dbReference type="Rhea" id="RHEA:17017"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:10478"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="ChEBI" id="CHEBI:57288"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="ChEBI" id="CHEBI:83111"/>
            <dbReference type="EC" id="2.3.1.12"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 5">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the 2-oxoacid dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="5"/>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061944.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05360"/>
    <dbReference type="EnsemblBacteria" id="KPL78680">
        <property type="protein sequence ID" value="KPL78680"/>
        <property type="gene ID" value="ADN00_05360"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1544"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045254">
        <property type="term" value="C:pyruvate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016746">
        <property type="term" value="F:acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006086">
        <property type="term" value="P:acetyl-CoA biosynthetic process from pyruvate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.559.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001078">
        <property type="entry name" value="2-oxoacid_DH_actylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023213">
        <property type="entry name" value="CAT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045257">
        <property type="entry name" value="E2/Pdx1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036625">
        <property type="entry name" value="E3-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004167">
        <property type="entry name" value="PSBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23151">
        <property type="entry name" value="PTHR23151"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00198">
        <property type="entry name" value="2-oxoacid_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02817">
        <property type="entry name" value="E3_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47005">
        <property type="entry name" value="SSF47005"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51826">
        <property type="entry name" value="PSBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="4 5" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="6">
        <location>
            <begin position="2"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="Peripheral subunit-binding (PSBD)" evidence="7">
        <location>
            <begin position="128"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000925"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003423"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51826"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL78680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="449" mass="48018" checksum="7A9A098EC690F98C" modified="2016-01-20" version="1">MAKPVIMPKQGNSVETVILTAWKKQVGEVVAQGESLCEVETDKAVMDVESTADGTLLALFYQPGDEIPVMVNIAVVGQPGEDFSSFDPRGGSQPADADLVPANQPAALDLPAAALPPAPPAETASEIFISPRARELAKTKNVDYRQLTGSGPQGRIIERDILAALQSQPTLSPVAKAMLENGDFNLPEQGSGPRGRIMSKDLLPATPGQSSAQPVAEEPEYDVIPLKGMRKLIAERMMDSVLTTAQLTFNASADARALLALRRRYKDSPESYGLRKVTINDLVMFAVSRVLLDFPDINAHLVENQIRRFKNVHLAFAVDTPRGLTVPVIRNAHTLSPAQISAQANRLAAACQTGEVSPDNLSGGTFTVTNLGGLGIESFTPILNPPQVAILGVNTIQLKPVRVGGAVEFIDHISFSLTVNHQWVDGAPSARFLQAVVEAVTHIDLLLAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="5" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQ44</accession>
    <name>A0A0P6XQ44_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13845</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74369.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74369">
        <property type="protein sequence ID" value="KPL74369"/>
        <property type="gene ID" value="ADN00_13845"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133170" evidence="1">
        <location>
            <begin position="31"/>
            <end position="751"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74369.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="751" mass="80514" checksum="ADC50D6037B18260" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQE5</accession>
    <name>A0A0P6XQE5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">50S ribosomal protein L27</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rpmA</name>
        <name evidence="7" type="ORF">ADN00_03570</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the bacterial ribosomal protein bL27 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061592.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03570"/>
    <dbReference type="EnsemblBacteria" id="KPL78982">
        <property type="protein sequence ID" value="KPL78982"/>
        <property type="gene ID" value="ADN00_03570"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.65"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00539">
        <property type="entry name" value="Ribosomal_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001684">
        <property type="entry name" value="Ribosomal_L27"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018261">
        <property type="entry name" value="Ribosomal_L27_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15893">
        <property type="entry name" value="PTHR15893"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01016">
        <property type="entry name" value="Ribosomal_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00063">
        <property type="entry name" value="RIBOSOMALL27"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00062">
        <property type="entry name" value="L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00831">
        <property type="entry name" value="RIBOSOMAL_L27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 5 7" id="KW-0689">Ribosomal protein</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00029549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00539"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL78982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="87" mass="9197" checksum="56C3ECFF28614FE9" modified="2016-01-20" version="1">MAHKKGGGSSRNGRDSNSQRLGVKKFGGEQVISGNILVRQRGTKIKPGKNVGRGKDDTLFAVADGVVVFETLPTGQKRVHVEPAEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQZ8</accession>
    <name>A0A0P6XQZ8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Osmotically inducible protein OsmC</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_04790</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061816.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79247">
        <property type="protein sequence ID" value="KPL79247"/>
        <property type="gene ID" value="ADN00_04790"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015946">
        <property type="entry name" value="KH_dom-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003718">
        <property type="entry name" value="OsmC/Ohr_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036102">
        <property type="entry name" value="OsmC/Ohrsf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02566">
        <property type="entry name" value="OsmC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82784">
        <property type="entry name" value="SSF82784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="40"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="134" mass="14359" checksum="A59928E93627117C" modified="2016-01-20" version="1">MEMIVDFPGGARVDTHFGPYTVKTDQPPMGGGSGSAPTPFATFLASIGACAGIYVLSFLQQRNLPTDGVRLVQRAYSDPMTGMVSKIDLEIQVPEGFPERYLPALIRTADLCAVKKHLQHPPEIEVTAKAVATA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XRH2</accession>
    <name>A0A0P6XRH2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_15695</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72259.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72259">
        <property type="protein sequence ID" value="KPL72259"/>
        <property type="gene ID" value="ADN00_15695"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72259.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="144" mass="15171" checksum="68F3FF134DCB22BC" modified="2016-01-20" version="1">MSFADAEVAYQIEGDASPTDMSGFAASVEISGFETQIGEAYTAEGNTAILTAGKIAPGDVTVKAIYTENDADPTKKLFDAKAAKKKVKFIWYPRGNAATHYKWETDFGFLTTVNAGGGEASSPDALLAEFALKTAQISQTTVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XS76</accession>
    <name>A0A0P6XS76_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7 8">Elongation factor Tu</fullName>
            <shortName evidence="7">EF-Tu</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7 10" type="primary">tuf</name>
        <name evidence="10" type="ORF">ADN00_15070</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000037">
        <property type="protein sequence ID" value="KPL72478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063863.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000037.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15070"/>
    <dbReference type="EnsemblBacteria" id="KPL72478">
        <property type="protein sequence ID" value="KPL72478"/>
        <property type="gene ID" value="ADN00_15070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3397"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01884">
        <property type="entry name" value="EF_Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03697">
        <property type="entry name" value="EFTU_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00118_B">
        <property type="entry name" value="EF_Tu_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041709">
        <property type="entry name" value="EF-Tu_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033720">
        <property type="entry name" value="EFTU_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004541">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_bac/org"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004160">
        <property type="entry name" value="Transl_elong_EFTu/EF1A_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03143">
        <property type="entry name" value="GTP_EFTU_D3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="SSF50465"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00485">
        <property type="entry name" value="EF-Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3 7 10" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="5 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="9">
        <location>
            <begin position="10"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="19"/>
            <end position="26"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="81"/>
            <end position="85"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="136"/>
            <end position="139"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029554"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL72478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="399" mass="44158" checksum="C34ED4217400C346" modified="2016-01-20" version="1">MAKQKFERNKPHLNVGTMGHIDHGKTTLTAAITKYCAMLGGAEFRAYDQIDNAPEEKARGITINIAHVEYETAHRHYAHVDMPGHRDYIKNMITGAAQVDGAILVVAAPDGPMPQTKEHVLLAYQVEVPNICVFMNKTDQMDDPELLELVELELREMLTEYHFPGDEVPIVKGSALKALESTSTDPNAPEYACIKELMDTIDTYFPDPVREVDKPFMMPVEDVFSIKGRGTVVTGRAERGKIHTGDEVEIVGLRETRKSVCTGVEMFHKTLDEGMAGDNIGLLLRGINREDVERGMVIAAPKSITPHTKFQAEVYVLKKEEGGRHKPFFDGYRPQFYIRTMDVTGSIHLPEGVEMVMPGDNINMTAELIVPVALEQGSKFAIREGGLTVGAGVITKILA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XSZ2</accession>
    <name>A0A0P6XSZ2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH crp-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_12100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063275.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76079">
        <property type="protein sequence ID" value="KPL76079"/>
        <property type="gene ID" value="ADN00_12100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00090">
        <property type="entry name" value="HTH_ARSR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011991">
        <property type="entry name" value="ArsR-like_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012318">
        <property type="entry name" value="HTH_CRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00419">
        <property type="entry name" value="HTH_CRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH crp-type" evidence="1">
        <location>
            <begin position="15"/>
            <end position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00419"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="178" mass="19948" checksum="A956A31F7A070F06" modified="2016-01-20" version="1">MGTLTNDQRDLVILERIEVEPEATQASLADQLGVAVGTINWHIKRLISKGYVKVQRVERRKLRYIITPEGIALRARLTIDYIQSSFQLYRLVRQRMTEALAKVKVNGIQTICLEGEGDVAEICRLTALEQGFDVAEHQDGSPVLHIRGLKVFIDWGDGSAVIPDRLADLQNRSGSNPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XU97</accession>
    <name>A0A0P6XU97_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Alcohol dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_05560</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78711.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061981.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05560"/>
    <dbReference type="EnsemblBacteria" id="KPL78711">
        <property type="protein sequence ID" value="KPL78711"/>
        <property type="gene ID" value="ADN00_05560"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1589"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="SSF50129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ADH_N" evidence="2">
        <location>
            <begin position="49"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="domain" description="ADH_zinc_N" evidence="1">
        <location>
            <begin position="350"/>
            <end position="482"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78711.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="579" mass="62546" checksum="232DC68D2C649DB6" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUA1</accession>
    <name>A0A0P6XUA1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10185</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062895.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76948">
        <property type="protein sequence ID" value="KPL76948"/>
        <property type="gene ID" value="ADN00_10185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="9"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="34"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="137" mass="15109" checksum="A95D464CD704574A" modified="2016-01-20" version="1">MQKLTPKNLVCLGIELLIAGLHILGPGRRAGGEWFVLSASYFSDLTLPFGFYFLLCISEDQFRFLRPWWVKALLVFSAAVAAETLQALGVYALGGTFDPLDYGMYAAGVLLAAALEQGIMRRVLPFWEEKHAAVPRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUY2</accession>
    <name>A0A0P6XUY2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Sec-independent protein translocase protein TatA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">tatA</name>
        <name evidence="8" type="ORF">ADN00_03785</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Part of the twin-arginine translocation (Tat) system that transports large folded proteins containing a characteristic twin-arginine motif in their signal peptide across membranes. TatA could form the protein-conducting channel of the Tat system.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Forms a complex with TatC.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cell membrane</location>
            <topology evidence="7">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the TatA/E family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061632.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79022">
        <property type="protein sequence ID" value="KPL79022"/>
        <property type="gene ID" value="ADN00_03785"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033281">
        <property type="term" value="C:TAT protein transport complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008320">
        <property type="term" value="F:protein transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043953">
        <property type="term" value="P:protein transport by the Tat complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00236">
        <property type="entry name" value="TatA_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003369">
        <property type="entry name" value="TatA/B/E"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006312">
        <property type="entry name" value="TatA/E"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02416">
        <property type="entry name" value="TatA_B_E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0811">Translocation</keyword>
    <keyword evidence="2 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="1 7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL79022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="56" mass="5949" checksum="65BF6DFB5633069C" modified="2016-01-20" version="1">MPRIGLTELVVVLVIIVLLMGVGRIEKIAGELGAGIKAFKKGLSEEQSDEGKKDAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XVU5</accession>
    <name>A0A0P6XVU5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Riboflavin biosynthesis protein</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="11">Riboflavin kinase</fullName>
                <ecNumber evidence="11">2.7.1.26</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="11">Flavokinase</fullName>
            </alternativeName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="11">FMN adenylyltransferase</fullName>
                <ecNumber evidence="11">2.7.7.2</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="11">FAD pyrophosphorylase</fullName>
            </alternativeName>
            <alternativeName>
                <fullName evidence="11">FAD synthase</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="13" type="ORF">ADN00_02680</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="2 11">
            <text>ATP + FMN + H(+) = diphosphate + FAD</text>
            <dbReference type="Rhea" id="RHEA:17237"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="EC" id="2.7.7.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>ATP + riboflavin = ADP + FMN + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14357"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:57986"/>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.26"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 11">Cofactor biosynthesis; FAD biosynthesis; FAD from FMN: step 1/1.</text>
    </comment>
    <comment type="pathway">
        <text evidence="4 11">Cofactor biosynthesis; FMN biosynthesis; FMN from riboflavin (ATP route): step 1/1.</text>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the ribF family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.26" evidence="11"/>
    <dbReference type="EC" id="2.7.7.2" evidence="11"/>
    <dbReference type="EMBL" id="LGCL01000012">
        <property type="protein sequence ID" value="KPL79443.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02680"/>
    <dbReference type="EnsemblBacteria" id="KPL79443">
        <property type="protein sequence ID" value="KPL79443"/>
        <property type="gene ID" value="ADN00_02680"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2364"/>
    <dbReference type="UniPathway" id="UPA00276">
        <property type="reaction ID" value="UER00406"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00277">
        <property type="reaction ID" value="UER00407"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003919">
        <property type="term" value="F:FMN adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008531">
        <property type="term" value="F:riboflavin kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006747">
        <property type="term" value="P:FAD biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009398">
        <property type="term" value="P:FMN biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009231">
        <property type="term" value="P:riboflavin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02064">
        <property type="entry name" value="FAD_synthetase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015864">
        <property type="entry name" value="FAD_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023468">
        <property type="entry name" value="Riboflavin_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002606">
        <property type="entry name" value="Riboflavin_kinase_bac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015865">
        <property type="entry name" value="Riboflavin_kinase_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023465">
        <property type="entry name" value="Riboflavin_kinase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22749">
        <property type="entry name" value="PTHR22749"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06574">
        <property type="entry name" value="FAD_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01687">
        <property type="entry name" value="Flavokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004491">
        <property type="entry name" value="FAD_Synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00904">
        <property type="entry name" value="Flavokinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82114">
        <property type="entry name" value="SSF82114"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00083">
        <property type="entry name" value="ribF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="9 11" id="KW-0274">FAD</keyword>
    <keyword evidence="5 11" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="6 11" id="KW-0288">FMN</keyword>
    <keyword evidence="11" id="KW-0418">Kinase</keyword>
    <keyword evidence="8 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 11" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Flavokinase" evidence="12">
        <location>
            <begin position="183"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRNR" id="PIRNR004491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00904"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KPL79443.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="319" mass="35994" checksum="62B38DEFE9F9DACE" modified="2016-01-20" version="1">MQHFYGLENIQYQHQHTWITIGSFDGVHLGHQTIIKDMVASAHQHQAKAVVITFHPHPAVVLRGLDKPYYLTMPEERAALMAELGVDAVVTLTFTRELAALSASDFMRNITEKLNPRELWVGSDFALGRNREGNVEQLKVIGQSLGFQTRVIQAVMKNGSEKISSSRIRQLLEQGEIEHASQLLGRWYSLESTVIRGDGRGRLLGFPTANLELPLERILPAPGVYATWAWLNGARHPSVTSVGFRPTFTDTPPIPRVEAFIFDFQQDIYGETLSLQFIRRLRFEEKFETVQALIDQMQQDSSQAREVLSHAQPTPDLPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XW90</accession>
    <name>A0A0P6XW90_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">5'-nucleotidase SurE</fullName>
            <ecNumber evidence="5">3.1.3.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Nucleoside 5'-monophosphate phosphohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">surE</name>
        <name evidence="7" type="ORF">ADN00_14735</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>a ribonucleoside 5'-phosphate + H2O = a ribonucleoside + phosphate</text>
            <dbReference type="Rhea" id="RHEA:12484"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:18254"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58043"/>
            <dbReference type="EC" id="3.1.3.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="5">Binds 1 divalent metal cation per subunit.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the SurE nucleotidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.5" evidence="5"/>
    <dbReference type="EMBL" id="LGCL01000035">
        <property type="protein sequence ID" value="KPL73593.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063794.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000035.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14735"/>
    <dbReference type="EnsemblBacteria" id="KPL73593">
        <property type="protein sequence ID" value="KPL73593"/>
        <property type="gene ID" value="ADN00_14735"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2113"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106411">
        <property type="term" value="F:XMP 5'-nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1210.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00060">
        <property type="entry name" value="SurE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030048">
        <property type="entry name" value="SurE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002828">
        <property type="entry name" value="SurE-like_Pase/nucleotidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036523">
        <property type="entry name" value="SurE-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30457">
        <property type="entry name" value="PTHR30457"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01975">
        <property type="entry name" value="SurE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64167">
        <property type="entry name" value="SSF64167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00087">
        <property type="entry name" value="surE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SurE" evidence="6">
        <location>
            <begin position="3"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="8"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="9"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="39"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="95"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00060"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL73593.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="255" mass="26996" checksum="E34EAECEEF9B3C33" modified="2016-01-20" version="1">MHILVTNDDGIEAPGLLALAQAVLPLGKVSVVAPDRNWSMCGHVKTIHRRLPITETHLADGTPAIATGGAPSDCVAMAVMGLLPEPVDLVVSGVNPFANIGHDLTYSGTVTAAMEAVIWGVPGLAFSLDGQTPTGLDYSACALVAREVVQRALQNGIPAETLLNVNIPNLPYAEIKGYQITRQGKRIYRDALVEHPEENGLRHLSIGGEPPIGVPEEGTDSGALAQGCVSITPIQLDLTAYAAMQTLEKWDWEKN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XWA9</accession>
    <name>A0A0P6XWA9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_01270</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000003">
        <property type="protein sequence ID" value="KPL80847.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061150.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000003.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80847">
        <property type="protein sequence ID" value="KPL80847"/>
        <property type="gene ID" value="ADN00_01270"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL80847.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="79" mass="8973" checksum="2805CAF37CAB969D" modified="2016-01-20" version="1">MNDEFVHDPYTALALAVIYHAVLDLESSNPARVAEAHAWLQFEGMNWCQMLGISEEELESWAASGFPLPPNAHRNWRYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XWK9</accession>
    <name>A0A0P6XWK9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Inositol-3-phosphate synthase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_08140</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the myo-inositol 1-phosphate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062490.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08140"/>
    <dbReference type="EnsemblBacteria" id="KPL77844">
        <property type="protein sequence ID" value="KPL77844"/>
        <property type="gene ID" value="ADN00_08140"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.628"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004512">
        <property type="term" value="F:inositol-3-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006021">
        <property type="term" value="P:inositol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008654">
        <property type="term" value="P:phospholipid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002587">
        <property type="entry name" value="Myo-inos-1-P_Synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013021">
        <property type="entry name" value="Myo-inos-1-P_Synthase_GAPDH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01658">
        <property type="entry name" value="Inos-1-P_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015578">
        <property type="entry name" value="Myoinos-ppht_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Inos-1-P_synth" evidence="2">
        <location>
            <begin position="193"/>
            <end position="301"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="361" mass="40138" checksum="BF374DD5EE9CBFCF" modified="2016-01-20" version="1">MSNKKVRVAIIGVGNCASSLVQGVHFYRNAKDTDQVPGLMHVNLGGYHISDVEFSAAFDVVTTKVGKDLSEAIYAYPNNTYKFCDVPHMGVKVNRGMTHDGLGKYLSEVVEKAPGPTDNIVQILKDTKTDVVVNYLPVGSEMATKWYVEQVLEAGCAFVNAIPVFISSSEYWSKRFVERGLPIIGDDIKSQVGATITHRVLTSLFVDRGVRLDRTYQLNFGGNTDFLNMLERERLESKKISKTGAVTSMLPYEIDHNNIHVGPSDYVPWLTDRKWCYIRMEGTTFGEVPLNAELKLEVWDSPNSAGVIIDAVRCAKLALDRGMSGPIYAPASYFMKTPPKQFKDSIARDMTEAFIRGEVSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XWT8</accession>
    <name>A0A0P6XWT8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">UDP-N-acetyl-D-glucosamine dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_01890</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the UDP-glucose/GDP-mannose dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000007">
        <property type="protein sequence ID" value="KPL80046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01890"/>
    <dbReference type="EnsemblBacteria" id="KPL80046">
        <property type="protein sequence ID" value="KPL80046"/>
        <property type="gene ID" value="ADN00_01890"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2304"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016628">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016616">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000271">
        <property type="term" value="P:polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017476">
        <property type="entry name" value="UDP-Glc/GDP-Man"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014027">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036220">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014026">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001732">
        <property type="entry name" value="UDP-Glc/GDP-Man_DH_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028359">
        <property type="entry name" value="UDP_ManNAc/GlcNAc_DH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00984">
        <property type="entry name" value="UDPG_MGDP_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03720">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03721">
        <property type="entry name" value="UDPG_MGDP_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF500136">
        <property type="entry name" value="UDP_ManNAc_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000124">
        <property type="entry name" value="UDPglc_GDPman_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00984">
        <property type="entry name" value="UDPG_MGDP_dh_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52413">
        <property type="entry name" value="SSF52413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03026">
        <property type="entry name" value="NDP-sugDHase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0520">NAD</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UDPG_MGDP_dh_C" evidence="4">
        <location>
            <begin position="336"/>
            <end position="431"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRNR" id="PIRNR000124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL80046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="442" mass="47980" checksum="4D6556EA296AE39B" modified="2016-01-20" version="1">MGMSDEIRSALAARIRDHSAKVAVMGLGYVGLPLAVVFAEAGYTVVGIDPIESKVESINRGESYVMDIPSEQLAALVSAGKLRATTDTSVLAEADAVSICVPTPLRKTGDPDLSFIVSATESLAPFLHSGMVVVLESSTYPGTTRELMLPVLTECCELQAGRDFFLAFSPERVDPGRKDWTTINTPKVVGGITPQCSDMAELWYGQALQTVVKVSSCEVAEMSKLLENTFRMINIGLVNELAIMCDRLGVDVWEVIDAAATKPFGFMKFTPGPGLGGHCIPIDPLYLSWKLKSLNYTARFIELASEINTGMPRFVLRKVQDALNEAGKPLKNSRVLVLGAAYKPDIDDMRESPALDVIGLLMQLKADVRYHDPFVPKIEHDGWALHSVDDLMKEVAAADCVVIITNHSSYDYAAILEQASLIVDTRNGLGAMGKNQSKVVRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XY10</accession>
    <name>A0A0P6XY10_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">PNPLA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_07290</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062321.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07290"/>
    <dbReference type="EnsemblBacteria" id="KPL78264">
        <property type="protein sequence ID" value="KPL78264"/>
        <property type="gene ID" value="ADN00_07290"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="SSF52151"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="1 2" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="3">
        <location>
            <begin position="10"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXGXXG" evidence="2">
        <location>
            <begin position="14"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="2">
        <location>
            <begin position="46"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="2">
        <location>
            <begin position="174"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="48"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="2">
        <location>
            <position position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL78264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="315" mass="35408" checksum="E255576F41AF9597" modified="2016-01-20" version="1">MKPFRKHVAIAIDGGGIRGLIVTKALAVLEAELGRPLHEIIEMAVGTSTGSIISAGLGAGMSASRMVELYLQMGSTIFPRSWRSRLWPLTRCRYPAEPLQSSLEQTFGAFQMSDFWNHRPPIDVVITTFDLVTNHTCFVKPWKPEYASWPVVKAVQASCTVPTYFPVVENRYIDGGVGAYSNPCYLAAYEALICLGWNPAETTLISLGTGREPRSFQTHTARRFWPWQWLNPILGAFLQSADDQQVHLVQTFFDQIDFRRFQVDLLTPFPMDDTSRPEELLRYGETLGRMILADQIDDAQKIIPQKLISTGSPRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XYB6</accession>
    <name>A0A0P6XYB6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_14125</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the glycosyltransferase 87 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74133.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74133">
        <property type="protein sequence ID" value="KPL74133"/>
        <property type="gene ID" value="ADN00_14125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018584">
        <property type="entry name" value="GT87"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09594">
        <property type="entry name" value="GT87"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="58"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="80"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="114"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="141"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="178"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="216"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="263"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="293"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00024033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL74133.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="332" mass="37569" checksum="4B7359F50AF3781C" modified="2016-01-20" version="1">MFAMENIDHRIFKKPSAGEFAAIVFVLTISISFVVCHTGDFVDFKAYLARTKGDFSQYFYGYWLLPFFQILSWLPFEASYILWIGLSVLGVWFAARVFNGNSALALLSYQMSSVLFWGQITGILCGLLGLFWWSIHHRRWWMAGIACFLAAAKPQSGTIFVFLLLLFSNTSFREKIRILIIPMVGFIVSLLFYPGWILEILSRRGAVYTAGNISLWQWIGPWAMLLSLPALVIPATKQQRFLALSAAWVLSIPYFSLPDLLTLFIFPVEIAPILLGYLPGILMQFFGFESQKAGFVIPLLILAMNLLPHFLQSKAAQKKLRLPAAGEQKPNN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y056</accession>
    <name>A0A0P6Y056_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">1-phosphofructokinase</fullName>
            <ecNumber evidence="3">2.7.1.56</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Fructose 1-phosphate kinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ADN00_05565</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + beta-D-fructose 1-phosphate = ADP + beta-D-fructose 1,6-bisphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:14213"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:32966"/>
            <dbReference type="ChEBI" id="CHEBI:138881"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.56"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the carbohydrate kinase PfkB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.56" evidence="3"/>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78712.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061982.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05565"/>
    <dbReference type="EnsemblBacteria" id="KPL78712">
        <property type="protein sequence ID" value="KPL78712"/>
        <property type="gene ID" value="ADN00_05565"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1590"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008662">
        <property type="term" value="F:1-phosphofructokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd01164">
        <property type="entry name" value="FruK_PfkB_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1190.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022463">
        <property type="entry name" value="1-PFruKinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002173">
        <property type="entry name" value="Carboh/pur_kinase_PfkB_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011611">
        <property type="entry name" value="PfkB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029056">
        <property type="entry name" value="Ribokinase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017583">
        <property type="entry name" value="Tagatose/fructose_Pkinase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00294">
        <property type="entry name" value="PfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000535">
        <property type="entry name" value="1PFK/6PFK/LacC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53613">
        <property type="entry name" value="SSF53613"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03168">
        <property type="entry name" value="1-PFK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03828">
        <property type="entry name" value="pfkB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00584">
        <property type="entry name" value="PFKB_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 10" id="KW-0418">Kinase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PfkB" evidence="9">
        <location>
            <begin position="12"/>
            <end position="290"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013596"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRNR" id="PIRNR000535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00294"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL78712.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="309" mass="32541" checksum="CAE13264E3585FC5" modified="2016-01-20" version="1">MIYTLTLNPAVDRELTVPEVVYDAVLRASSSRVDFGGKGFNVSRLLKGLGVTSTAVGFVGGKAGELLQDGLRSLGIETGFVWVDGETRTNISIVTQAGGHYIKVNEQGPFVDEAKQLELLELIGTLAQPGDWWVLAGSLPPGVAPDFYARVIRALNTRQAQAVLDTGGESLRAGCAERPFLAKPNTEEARALTGMPMDTLEQVSLAAAEIRRMGAQNVVVSMGKQGALLQTDRETCLVHSPKVTEKNPIGAGDSMVGGLVWALTQGFGLKESLGWGVASGAATASLSGTEVGSRALIESLLSQVVYQSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y216</accession>
    <name>A0A0P6Y216_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">3-methyl-2-oxobutanoate hydroxymethyltransferase</fullName>
            <ecNumber evidence="5">2.1.2.11</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Ketopantoate hydroxymethyltransferase</fullName>
            <shortName evidence="5">KPHMT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">panB</name>
        <name evidence="9" type="ORF">ADN00_03690</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha-ketoisovalerate to form ketopantoate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>(6R)-5,10-methylene-5,6,7,8-tetrahydrofolate + 3-methyl-2-oxobutanoate + H2O = (6S)-5,6,7,8-tetrahydrofolate + 2-dehydropantoate</text>
            <dbReference type="Rhea" id="RHEA:11824"/>
            <dbReference type="ChEBI" id="CHEBI:11561"/>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15636"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="EC" id="2.1.2.11"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5 8">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="5 8">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="5">Cofactor biosynthesis; (R)-pantothenate biosynthesis; (R)-pantoate from 3-methyl-2-oxobutanoate: step 1/2.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2 5">Homodecamer; pentamer of dimers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the PanB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.11" evidence="5"/>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061615.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03690"/>
    <dbReference type="EnsemblBacteria" id="KPL79005">
        <property type="protein sequence ID" value="KPL79005"/>
        <property type="gene ID" value="ADN00_03690"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.90"/>
    <dbReference type="UniPathway" id="UPA00028">
        <property type="reaction ID" value="UER00003"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003864">
        <property type="term" value="F:3-methyl-2-oxobutanoate hydroxymethyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06557">
        <property type="entry name" value="KPHMT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00156">
        <property type="entry name" value="PanB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003700">
        <property type="entry name" value="Pantoate_hydroxy_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_Kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20881">
        <property type="entry name" value="PTHR20881"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02548">
        <property type="entry name" value="Pantoate_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000388">
        <property type="entry name" value="Pantoate_hydroxy_MeTrfase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="SSF51621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00222">
        <property type="entry name" value="panB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="3 5" id="KW-0566">Pantothenate biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 9" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Alpha-ketoisovalerate binding" evidence="5 7">
        <location>
            <begin position="52"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5 6">
        <location>
            <position position="190"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 8">
        <location>
            <position position="52"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 7 8">
        <location>
            <position position="91"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5 7">
        <location>
            <position position="121"/>
        </location>
        <ligand>
            <name>3-methyl-2-oxobutanoate</name>
            <dbReference type="ChEBI" id="CHEBI:11851"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 8">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011424"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR000388-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000388-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000388-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL79005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="292" mass="31921" checksum="4D320208CD9C2750" modified="2016-01-20" version="1">MSTLPADRKKVTTTTFLQKKKKGQPISMLTAYDYPSALAADAARFDSILVGDSLGMVVLGYENTLPVTMQDMLHHCKAVARGASKALLIGDMPFMSYQASIDEAVRNAGRFLQEASMDAVKLEGGQERAEAIRRIVQAGIPVCGHIGLTPQSVQVFGGFKMQGKTALTAQKLLQDALALQEAGCFTLVLESIPEQLAAAITQRLEIPTIGIGAGANCDGQVLVYHDVLGLFDRFVPRFARQYANLNQQIHTALTQFREEIDSRAFPTPENSTAMQPEEWQAFSEWLTNARLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y391</accession>
    <name>A0A0P6Y391_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Cation_ATPase_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_12150</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063285.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12150"/>
    <dbReference type="EnsemblBacteria" id="KPL76089">
        <property type="protein sequence ID" value="KPL76089"/>
        <property type="gene ID" value="ADN00_12150"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3906"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="SSF56784"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="SSF81660"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="SSF81665"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-1278">Translocase</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="91"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="256"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="284"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="806"/>
            <end position="826"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="846"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="884"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="915"/>
            <end position="931"/>
        </location>
    </feature>
    <feature type="domain" description="Cation_ATPase_N" evidence="8">
        <location>
            <begin position="15"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL76089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="950" mass="104179" checksum="3051BB2AC1C5F75A" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y3Y1</accession>
    <name>A0A0P6Y3Y1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N_BRCA1_IG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_02435</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000010">
        <property type="protein sequence ID" value="KPL79672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061366.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000010.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02435"/>
    <dbReference type="EnsemblBacteria" id="KPL79672">
        <property type="protein sequence ID" value="KPL79672"/>
        <property type="gene ID" value="ADN00_02435"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14947">
        <property type="entry name" value="NBR1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032350">
        <property type="entry name" value="N_BRCA1_central"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16158">
        <property type="entry name" value="N_BRCA1_IG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133355" description="N_BRCA1_IG domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="N_BRCA1_IG" evidence="2">
        <location>
            <begin position="100"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="375" mass="39401" checksum="595340109A1F2D9A" modified="2016-01-20" version="1">MFKKHPWIFLILILALAAFACNFPGAAATLTPTPDPAQQALTLVAQTEQAAAAATLAATQPVITVPPTVTLAPFSGSTPAPASTSTSLPCDQAGFVTDVTIPDGTQLEPNKEFIKTWRLKNTGSCTWTTSYAVVFDSGDAMNAPVSTSLTGSVAPGQTIDISVSMKAPTAEGTYRGNWKLRNASGAVFGLGASNSAFYVEIEVKNTPSSGPTVIYNFAEKYCEAEWISAAGVLACPGGTGDSSGFVIKLSNPKMETGDFANKVSIQTHPQWIDNGAISGRFPAVAVQSGYRFKADIGCLHNGSACDVKYQLNYRVDGGPLQSLGTWGEKYDAALTSLNVDLSSLAGSSVQFILAVQSNGPSNQDWAVWVNPRIEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y863</accession>
    <name>A0A0P6Y863_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_08145</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062491.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08145"/>
    <dbReference type="EnsemblBacteria" id="KPL77845">
        <property type="protein sequence ID" value="KPL77845"/>
        <property type="gene ID" value="ADN00_08145"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="31"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="153"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="153"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL77845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="256" mass="29040" checksum="2D5F715C3511491A" modified="2016-01-20" version="1">MEELTSKEVKQEVSSGIGVDLDQVDGQERQRILVIDDEADTSYLLKQILRIAGYNVLSAANGAEAIKKTMEYSPNLILLDIMMPEMDGWQTFEYLKRMTNVPVIVVSALTSKDHIVDGLRQGIDDYIPKPFYNAEVIERVNAVLRRTNRPQEITRLVFPSVGLTIDLINQEVELLGNSIRLTPKEFSVLSVLAKNAPAIVPYEKISHLVWGEDSSDVRKRTKYLIYLLRQKFDKISSGSQLILNVDRLGYKLQTEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YAP8</accession>
    <name>A0A0P6YAP8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase_C39_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_03490</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061577.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03490"/>
    <dbReference type="EnsemblBacteria" id="KPL78969">
        <property type="protein sequence ID" value="KPL78969"/>
        <property type="gene ID" value="ADN00_03490"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.49"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039564">
        <property type="entry name" value="Peptidase_C39-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13529">
        <property type="entry name" value="Peptidase_C39_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133460" description="Peptidase_C39_2 domain-containing protein" evidence="1">
        <location>
            <begin position="27"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_C39_2" evidence="2">
        <location>
            <begin position="120"/>
            <end position="263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="292" mass="31125" checksum="0D2CE54D6DBED148" modified="2016-01-20" version="1">MPTPHFPQIRASLLAAALLLTTSACGQMDFSRGLESAEVVFAGLDPAKITWFSTPTLTAAPTADPTPTPTTTFTITPTPFQPLPTATITPTPTSVPPTETPQPAPEIPESASLSNIYGTSQQLPLDCESNSATDFARYFAVNIDELEFFNGLPVSDDPETGFVGSVWGPASLPPYGYGVHSGPVASLLRSYGLNAWERRGMSFDDVKVEISAGRPVMVWVVGSVFPGSPVSYTASSGSTATVAYLEHTVLVIGYDSNTVTILDADMLYYRSIDQFLSSWSVLGNMAIVVEQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YCQ3</accession>
    <name>A0A0P6YCQ3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_02235</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000009">
        <property type="protein sequence ID" value="KPL79801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061333.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000009.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79801">
        <property type="protein sequence ID" value="KPL79801"/>
        <property type="gene ID" value="ADN00_02235"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="160"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="166" mass="18246" checksum="E04E343F84952118" modified="2016-01-20" version="1">MRKLISIPVLLAALMLQMVAVSRLRLIGGSADLVLMVLIAWGMQEQVKDLWVWVVVASLMTSFVSALPVFAVVAGYLFAAFFIWFLKQQVWQSPILAMFLATAVSTLVQNLASIFALQISGSPISFSEGFNLVTVPSMLLNFLLVLPLYALFTDLAGFVYPVEEVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YFQ4</accession>
    <name>A0A0P6YFQ4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Transcription antitermination protein NusB</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Antitermination factor NusB</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">nusB</name>
        <name evidence="8" type="ORF">ADN00_00330</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in transcription antitermination. Required for transcription of ribosomal RNA (rRNA) genes. Binds specifically to the boxA antiterminator sequence of the ribosomal RNA (rrn) operons.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6">Belongs to the NusB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81027.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060963.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00330"/>
    <dbReference type="EnsemblBacteria" id="KPL81027">
        <property type="protein sequence ID" value="KPL81027"/>
        <property type="gene ID" value="ADN00_00330"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3459"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006353">
        <property type="term" value="P:DNA-templated transcription, termination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031564">
        <property type="term" value="P:transcription antitermination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.940.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00073">
        <property type="entry name" value="NusB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035926">
        <property type="entry name" value="NusB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011605">
        <property type="entry name" value="NusB_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006027">
        <property type="entry name" value="NusB_RsmB_TIM44"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11078">
        <property type="entry name" value="PTHR11078"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01029">
        <property type="entry name" value="NusB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48013">
        <property type="entry name" value="SSF48013"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01951">
        <property type="entry name" value="nusB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5 6" id="KW-0804">Transcription</keyword>
    <keyword evidence="2 6" id="KW-0889">Transcription antitermination</keyword>
    <keyword evidence="4 6" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="NusB" evidence="7">
        <location>
            <begin position="6"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01029"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL81027.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="147" mass="16466" checksum="88C8EC4BA8AA87BB" modified="2016-01-20" version="1">MKSRTKARSLALQVLYEVDLSGHMPGEVFEEHLNTTHLEDELLEFSRQLIFGVYPIMQALDSFIAQHAPEWPLDQVAVIDRNIIRMALWEFAVEGCTPIKVAINEAIELAKMFGSDSSPRFVNGVLGSLAARQNEINVAFGPKPDKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YFX1</accession>
    <name>A0A0P6YFX1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glycine cleavage system H protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="primary">gcvH</name>
        <name evidence="6" type="ORF">ADN00_00875</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3">
            <name>(R)-lipoate</name>
            <dbReference type="ChEBI" id="CHEBI:83088"/>
        </cofactor>
        <text evidence="3">Binds 1 lipoyl cofactor covalently.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">The glycine cleavage system is composed of four proteins: P, T, L and H.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the GcvH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061060.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00875"/>
    <dbReference type="EnsemblBacteria" id="KPL81109">
        <property type="protein sequence ID" value="KPL81109"/>
        <property type="gene ID" value="ADN00_00875"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3573"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005960">
        <property type="term" value="C:glycine cleavage complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019464">
        <property type="term" value="P:glycine decarboxylation via glycine cleavage system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06848">
        <property type="entry name" value="GCS_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00272">
        <property type="entry name" value="GcvH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003016">
        <property type="entry name" value="2-oxoA_DH_lipoyl-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002930">
        <property type="entry name" value="GCV_H"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033753">
        <property type="entry name" value="GCV_H/Fam206"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017453">
        <property type="entry name" value="GCV_H_sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11715">
        <property type="entry name" value="PTHR11715"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01597">
        <property type="entry name" value="GCV_H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00527">
        <property type="entry name" value="gcvH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50968">
        <property type="entry name" value="BIOTINYL_LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00189">
        <property type="entry name" value="LIPOYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 3 4" id="KW-0450">Lipoyl</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="5">
        <location>
            <begin position="22"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-lipoyllysine" evidence="3 4">
        <location>
            <position position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR617453-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL81109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="130" mass="13873" checksum="3F8261C59D133BEF" modified="2016-01-20" version="1">MKIPGELKYTKGDEWVKVEGNIATIGITDYAQDHLSDVVFVEISVSVDDMVKAGTTVATLESVKAAADVNAPVSGKVVEVNEGLADAPDTVNSDPYAGAWMLKVEMSAPAELDALMDAAAYEKYCEERES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GKM7</accession>
    <name>A0A0N8GKM7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">23S rRNA methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_19015</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70130.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064619.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_19015"/>
    <dbReference type="EnsemblBacteria" id="KPL70130">
        <property type="protein sequence ID" value="KPL70130"/>
        <property type="gene ID" value="ADN00_19015"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3115"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002478">
        <property type="entry name" value="PUA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041532">
        <property type="entry name" value="RlmI_PUA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019614">
        <property type="entry name" value="SAM-dep_methyl-trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10672">
        <property type="entry name" value="Methyltrans_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17785">
        <property type="entry name" value="PUA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00359">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="SSF88697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 5" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PUA" evidence="4">
        <location>
            <begin position="2"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL70130.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="396" mass="42770" checksum="97DA8B038336AF4E" modified="2016-01-20" version="1">MKSIRLKEQKEKTVLQGHPWIFSGAIAEMKGSPGMGETVGVLSSAGKWLGSAAFSPSSKIQARMWTRDENEPVDASFFARRIAAAIQARKDLGLLDASNNAVRLVHAESDGLPGVIVDQYADVVVVQLLSAGAEAWRQVIADQLLQASGAKSVYERSDVDVRKLEALPARTGLLAGEPVADEIEVVESGLRFLVDVKRGQKTGFYLDQRQNRQRLGEMARGKRVLNCFCYTGGFSMYAAKGGAAQVISVDSSAEALETARRNADLNGLLADSMAWVEQDVFTYLRGQRDRNERYDLIILDPPKFAPTAAQAQQAARGYKDINLLAFKLLNPGGLLFTYSCSGGISADLFQKIVAGAAADAGARARIIGTMTQGPDHPVALVFPESAYLKGLICQML</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMS5</accession>
    <name>A0A0N8GMS5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_12295</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063311.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12295"/>
    <dbReference type="EnsemblBacteria" id="KPL76114">
        <property type="protein sequence ID" value="KPL76114"/>
        <property type="gene ID" value="ADN00_12295"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014942">
        <property type="entry name" value="AbiEii"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08843">
        <property type="entry name" value="AbiEii"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="269" mass="30919" checksum="0C9A6C2011D7F940" modified="2016-01-20" version="1">MKEYLFSLVKQTASPMEGRNLIREYLQARILESLQRCGAMIPLAFHGGTALHFLYSHGRYSEDLDFALEGNRDNYDFRAYLRSIRADLSPEGYLVELKVNDQKTVHSAFIRFPGLFYEMGLSPMRSEVLAVKIEVDTNPPTGAGLATTVVRRFVVLQLHHHDKASLLSGKLHAILQRAYTKGRDLYDLLWYLSDPTWPEPNLILLNNALKQTHWDGMALTRATWKEIVWRRLESVDWASIANDVRPFVEPSFNLDLLTPGNFERLLREA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GND7</accession>
    <name>A0A0N8GND7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_07940</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77810.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062454.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77810">
        <property type="protein sequence ID" value="KPL77810"/>
        <property type="gene ID" value="ADN00_07940"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="79"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="139"/>
            <end position="162"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77810.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="177" mass="19898" checksum="888DF4CCAC2B250F" modified="2016-01-20" version="1">METIQNSAKHNWKRDLRSKILDGFFAGWLLLFLLIVLRIIVDPIGYRFGRLGLLNYDVFLIALAVFCLERALSARRADTTLAWLGAVGGLLTWSAVELSCMVGQTPLVALTGVMLFILILLIVFVLWRKGLSVGGKFYMMVVLICWLVKYILAGQEFVRVWLPAFSPDLHLVGLPLC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNE1</accession>
    <name>A0A0N8GNE1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HIT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_08130</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062488.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77842">
        <property type="protein sequence ID" value="KPL77842"/>
        <property type="gene ID" value="ADN00_08130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019808">
        <property type="entry name" value="Histidine_triad_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001310">
        <property type="entry name" value="Histidine_triad_HIT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23089">
        <property type="entry name" value="PTHR23089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01230">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00332">
        <property type="entry name" value="HISTRIAD"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="SSF54197"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00892">
        <property type="entry name" value="HIT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HIT" evidence="2">
        <location>
            <begin position="5"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Histidine triad motif" evidence="1">
        <location>
            <begin position="98"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="114" mass="12796" checksum="B403B7EAC1DAEECC" modified="2016-01-20" version="1">MDTCVFCKIVANEIPHRRFYHDELVTAFEDRSPIAPVHILIVPNHHIESLNQAQAGDEQLFGHMLLVARQMAAQMKLDQSGYRLVINTGPDAGQSVFHLHLHIIGGRKLSFSGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNJ5</accession>
    <name>A0A0N8GNJ5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 7">Transcriptional regulator MraZ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">mraZ</name>
        <name evidence="10" type="ORF">ADN00_07350</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="7">Forms oligomers.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
            <location evidence="7">Nucleoid</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the MraZ family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062333.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07350"/>
    <dbReference type="EnsemblBacteria" id="KPL78274">
        <property type="protein sequence ID" value="KPL78274"/>
        <property type="gene ID" value="ADN00_07350"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009295">
        <property type="term" value="C:nucleoid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd16321">
        <property type="entry name" value="MraZ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16320">
        <property type="entry name" value="MraZ_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1550.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01008">
        <property type="entry name" value="MraZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003444">
        <property type="entry name" value="MraZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035644">
        <property type="entry name" value="MraZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020603">
        <property type="entry name" value="MraZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035642">
        <property type="entry name" value="MraZ_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038619">
        <property type="entry name" value="MraZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007159">
        <property type="entry name" value="SpoVT-AbrB_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037914">
        <property type="entry name" value="SpoVT-AbrB_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34701">
        <property type="entry name" value="PTHR34701"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02381">
        <property type="entry name" value="MraZ"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89447">
        <property type="entry name" value="SSF89447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00242">
        <property type="entry name" value="TIGR00242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51740">
        <property type="entry name" value="SPOVT_ABRB"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 7 8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 7" id="KW-0804">Transcription</keyword>
    <keyword evidence="4 7" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="SpoVT-AbrB" evidence="9">
        <location>
            <begin position="5"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="domain" description="SpoVT-AbrB" evidence="9">
        <location>
            <begin position="76"/>
            <end position="119"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013860"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL78274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="147" mass="16896" checksum="F95EFBA00AE68C2A" modified="2016-01-20" version="1">MFLGQYEHSIDSKGRLTIPARFRDLLEDGAYITLGFDSSLMVMTSDYFNRMVQKINAMNMADPTSRQFRRFIFSKADHQEIDRAGRILIQQFLRDAVGLQDTVIVVGVGEYVEIWTPEAWNRQNEALLNAEETAERFASLDLTVSRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNK2</accession>
    <name>A0A0N8GNK2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_07720</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062402.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07720"/>
    <dbReference type="EnsemblBacteria" id="KPL78330">
        <property type="protein sequence ID" value="KPL78330"/>
        <property type="gene ID" value="ADN00_07720"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="259"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="309"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="357"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="432"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="664"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="711"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="764"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="291"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="697"/>
            <end position="789"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL78330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="798" mass="87662" checksum="E3A3D6552E89D1A6" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-06-17" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNQ4</accession>
    <name>A0A0N8GNQ4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_05765</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78746.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78746">
        <property type="protein sequence ID" value="KPL78746"/>
        <property type="gene ID" value="ADN00_05765"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78746.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="316" mass="33272" checksum="B8A113EA08C7A608" modified="2016-01-20" version="1">MDIGGTKTAVGLVDSSGYLHFQKQAPTCQDGPQHGFAQIIRLIEEVLFETRIGIDQVQGIGIGIPAVLEPETDFVIWGPNLAGWRNVDLRGALIDHFKVPVCVEYDGHTAVLGEWWIGAGKAYQSMVSIIIGTGLGGGMVLDGKLYRGMNRLAGAAGWFGLTLNAGMQSQRESSIGFWEARIAGPAISMRAQQFAAEHPNSMMASVSPPDRLTAQQVFEIAGKGDPAAQQFCEQIADEIGIGIANVVSLVDPQVVILGGGVGSNCGVLLPRIRQVVQSWAQPIAGKSVQLVLSTLGAKAGLVGAAYSVLLRNGAEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNU2</accession>
    <name>A0A0N8GNU2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_03970</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061667.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03970"/>
    <dbReference type="EnsemblBacteria" id="KPL79050">
        <property type="protein sequence ID" value="KPL79050"/>
        <property type="gene ID" value="ADN00_03970"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012505">
        <property type="entry name" value="YbbR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07949">
        <property type="entry name" value="YbbR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="411" mass="44029" checksum="1A2702B81F517CD4" modified="2016-01-20" version="1">MIDHLRQLGKNIPTFLLALILAVAAWISAVTTQDPTEQRVYPRAINVEVIGQDPGLVLTSTTPSTVSITLRAPNSIWNRLLNEQIPVRAVLDLSGLDAGTYNSEIQVQVGLRPVEIVSCTPCLLTVTLENLSSRELPISLVERGDLAVGFQAESPDFTPKAVIVSGPESLVEQVSEARAVLDYNQADRDISRSIPISTYNADGEQITGVSLSPEAVTVNVKVTQRGGYRNVVVKVVPVGQVAGGYRVTNISVFPPTVTIYSSDPKLVDEIPGYVETKALDLNGAKDDLDLRLPLDLPPGVSVVGEQTVAVQVGIAAIEGSLTLTDKKVEVIGLSDAFEATISPETVDVILSGPLPVLDQLISSEVRVIVDLTGEPMGTYQRVPTVQVNQPDVRIESILPGSIEVIVRRKSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GP17</accession>
    <name>A0A0N8GP17_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_02295</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000010">
        <property type="protein sequence ID" value="KPL79650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061344.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000010.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02295"/>
    <dbReference type="EnsemblBacteria" id="KPL79650">
        <property type="protein sequence ID" value="KPL79650"/>
        <property type="gene ID" value="ADN00_02295"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2674"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1260.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038330">
        <property type="entry name" value="TspO/MBR-related_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="203"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="226"/>
            <end position="246"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="255" mass="28013" checksum="BBC27CB23543E1C1" modified="2016-01-20" version="1">MNKDSLRQAAVVVSVLAALTVNILANALPINGQSTGEISDRFEVYFTPAGYVFSIWGVIFIGWLLLAVYQALPAQRENPRLRKIGYPFALSGLFNAGWLVLWHYNQFPATLAVMLVLLALLIVVYLCMEPRNPQVPAAEKWLVQLPVRVYLGWITVATIANLTALLDYLQWNGWGLRPEIWLVVVLSAALLVALAMARTQKDVAYLLVLVWSFVGIWVKHRAVPTVGAAALSAAVAVALLALASLVSRLRAARRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GP18</accession>
    <name>A0A0N8GP18_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_02345</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000010">
        <property type="protein sequence ID" value="KPL79658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061352.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000010.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02345"/>
    <dbReference type="EnsemblBacteria" id="KPL79658">
        <property type="protein sequence ID" value="KPL79658"/>
        <property type="gene ID" value="ADN00_02345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13426">
        <property type="entry name" value="PAS_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS" evidence="3">
        <location>
            <begin position="178"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="303"/>
            <end position="520"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL79658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="520" mass="58695" checksum="4A98649C441A4BD4" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GPJ3</accession>
    <name>A0A0N8GPJ3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glucose-6-phosphate 1-dehydrogenase</fullName>
            <shortName evidence="5">G6PD</shortName>
            <ecNumber evidence="5">1.1.1.49</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">zwf</name>
        <name evidence="9" type="ORF">ADN00_00555</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the oxidation of glucose 6-phosphate to 6-phosphogluconolactone.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>D-glucose 6-phosphate + NADP(+) = 6-phospho-D-glucono-1,5-lactone + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:15841"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:57955"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:61548"/>
            <dbReference type="EC" id="1.1.1.49"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="5">Carbohydrate degradation; pentose phosphate pathway; D-ribulose 5-phosphate from D-glucose 6-phosphate (oxidative stage): step 1/3.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the glucose-6-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.49" evidence="5"/>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00555"/>
    <dbReference type="EnsemblBacteria" id="KPL81058">
        <property type="protein sequence ID" value="KPL81058"/>
        <property type="gene ID" value="ADN00_00555"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3506"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00408"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004345">
        <property type="term" value="F:glucose-6-phosphate dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006006">
        <property type="term" value="P:glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00966">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001282">
        <property type="entry name" value="G6P_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019796">
        <property type="entry name" value="G6P_DH_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022675">
        <property type="entry name" value="G6P_DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022674">
        <property type="entry name" value="G6P_DH_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23429">
        <property type="entry name" value="PTHR23429"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02781">
        <property type="entry name" value="G6PD_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00479">
        <property type="entry name" value="G6PD_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000110">
        <property type="entry name" value="G6PD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00079">
        <property type="entry name" value="G6PDHDRGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00871">
        <property type="entry name" value="zwf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00069">
        <property type="entry name" value="G6P_DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="1 5" id="KW-0313">Glucose metabolism</keyword>
    <keyword evidence="2 5" id="KW-0521">NADP</keyword>
    <keyword evidence="3 5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G6PD_N" evidence="7">
        <location>
            <begin position="19"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="G6PD_C" evidence="8">
        <location>
            <begin position="199"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="5">
        <location>
            <position position="250"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="56"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="158"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="188"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5 6">
        <location>
            <position position="192"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="226"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="245"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="350"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022526"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF02781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL81058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="510" mass="58534" checksum="A08A5FB6483455A8" modified="2016-01-20" version="1">MRMDKLMNNSAQAVRTAFVIFGVTGDLTRRKLLPALYELDLSNRLDGELHLVGFARRDWSDEFLVEKMREGIDEFSRSKPVNGEAVSRLLSHSHYIKASFDDREGYLSLKRLLETEGIQNVLYYLATPPESYVEIIRQIGEIGLNQRFGGWTRIVVEKPYGRDLESARYLENEIRNVFEENQVYRIDHYLGKETVQNILVFRFANGIFEPLWNRRNVDHVQITVAETVGVGSRAGYYDSSGVIRDMYQNHLLQLLSLTAMEAPVAFNADAVRDEKVKVLRALRPMCDLDVLKNTYRAQYVSGILDGKRVPGYKEEERVDPKSTTETFLISRLFIDNWRWSGVPFYLRSGKRLPSRFTEIVIQFKQVPLSLFNWQNLAGDAPNMLILNLQPDEGITLTFGAKVPGPVNQISPVKMEFRYKTAFGREPPEAYERLLLDVLLGDATLFTRHDEAVAQWAYTNCILEGWNTHPISNLPVYEAGTWGPPGADEFIQKDARAWRNPIYESDSVDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WK02</accession>
    <name>A0A0P6WK02_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DsbD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_18125</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL69988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064457.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18125"/>
    <dbReference type="EnsemblBacteria" id="KPL69988">
        <property type="protein sequence ID" value="KPL69988"/>
        <property type="gene ID" value="ADN00_18125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017004">
        <property type="term" value="P:cytochrome complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003834">
        <property type="entry name" value="Cyt_c_assmbl_TM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02683">
        <property type="entry name" value="DsbD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="13"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="89"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="129"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="165"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="205"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="DsbD" evidence="2">
        <location>
            <begin position="19"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL69988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="225" mass="23643" checksum="8EB469DCF8837D1E" modified="2016-01-20" version="1">MNLDPTILQPTSILGYFLVFLGGIVTSIGPCNVAMIPLIIGYIGGTQYVPRKTAFQISLVFAVGLAVTFMLLGVAASLIGGLIGGGTRVWYYLVAAVCLLIGLQMLGVVRLSLPTSFGGLREKVKAKGLYGAFLLGLVSGLVASQCATPVLAAILTYVMAQRSGLLYGAVLLFIYSLGRGAPIILAGTFAGILKNLRAMGRFSEIYEKASGVVVILIGVYFLWLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WK44</accession>
    <name>A0A0P6WK44_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Peptidase M24</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_18460</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064522.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70043">
        <property type="protein sequence ID" value="KPL70043"/>
        <property type="gene ID" value="ADN00_18460"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3001"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_NTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000587">
        <property type="entry name" value="Creatinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01321">
        <property type="entry name" value="Creatinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="SSF53092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Creatinase_N" evidence="2">
        <location>
            <begin position="5"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M24" evidence="1">
        <location>
            <begin position="148"/>
            <end position="351"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL70043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="368" mass="39911" checksum="43024D5A2BB518C2" modified="2016-01-20" version="1">MTIHRFNRLKTILSSSSLDAIAIIPSPSLRYLTGLEFHLMERPVVLLIRADGQAAMVLPALEAGRLAGLSFSVTPFTYGDNPALWHTAFEQAAAHLKLESSVIGVESIHFRFLETQFLQTAAPHAKITAADTLLSELRMHKDLEEIAAMKKAVKIAQDALLATLNQVRLGITERQIAAELVSQLLRHGSDPELPFQPIVSTGPNSANPHATPTDRTLQAGELLLIDWGASSGGYISDLTRVMAFGPLPDELQTIHGLVHRANRAALAAARPGVPAGKVDQAARQVIEKGGYGAQFNHRVGHGIGLEAHEHPYMFTENQQILMRGAAFTIEPGIYLPGFGGVRIEDDVVITPDGAECLSDLPREIFQLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WPR4</accession>
    <name>A0A0P6WPR4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Transposase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_02105</name>
        <name evidence="4" type="ORF">ADN00_05125</name>
        <name evidence="3" type="ORF">ADN00_13130</name>
        <name evidence="2" type="ORF">ADN00_17955</name>
    </gene>
    <organism evidence="2 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000044">
        <property type="protein sequence ID" value="KPL70761.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="LGCL01000030">
        <property type="protein sequence ID" value="KPL75174.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78644.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="LGCL01000009">
        <property type="protein sequence ID" value="KPL79781.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70761">
        <property type="protein sequence ID" value="KPL70761"/>
        <property type="gene ID" value="ADN00_17955"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL75174">
        <property type="protein sequence ID" value="KPL75174"/>
        <property type="gene ID" value="ADN00_13130"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78644">
        <property type="protein sequence ID" value="KPL78644"/>
        <property type="gene ID" value="ADN00_05125"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79781">
        <property type="protein sequence ID" value="KPL79781"/>
        <property type="gene ID" value="ADN00_02105"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="20"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70761.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL75174.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL78644.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL79781.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="37" mass="4579" checksum="BC97955EE452D79C" modified="2016-01-20" version="1" fragment="single">AWLQNYRRILVRFDRLVENYIGFVHLGCLVILLKHYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WQ06</accession>
    <name>A0A0P6WQ06_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">50S ribosomal protein L1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">rplA</name>
        <name evidence="10" type="ORF">ADN00_17690</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Binds directly to 23S rRNA. The L1 stalk is quite mobile in the ribosome, and is involved in E site tRNA release.</text>
    </comment>
    <comment type="function">
        <text evidence="8">Protein L1 is also a translational repressor protein, it controls the translation of the L11 operon by binding to its mRNA.</text>
    </comment>
    <comment type="subunit">
        <text evidence="8">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 8 9">Belongs to the universal ribosomal protein uL1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000043">
        <property type="protein sequence ID" value="KPL70880.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064380.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000043.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17690"/>
    <dbReference type="EnsemblBacteria" id="KPL70880">
        <property type="protein sequence ID" value="KPL70880"/>
        <property type="gene ID" value="ADN00_17690"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2128"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00403">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.790">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01318_B">
        <property type="entry name" value="Ribosomal_L1_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005878">
        <property type="entry name" value="Ribosom_L1_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002143">
        <property type="entry name" value="Ribosomal_L1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023674">
        <property type="entry name" value="Ribosomal_L1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028364">
        <property type="entry name" value="Ribosomal_L1/biogenesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016095">
        <property type="entry name" value="Ribosomal_L1_3-a/b-sand"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023673">
        <property type="entry name" value="Ribosomal_L1_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00687">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002155">
        <property type="entry name" value="Ribosomal_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56808">
        <property type="entry name" value="SSF56808"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01169">
        <property type="entry name" value="rplA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01199">
        <property type="entry name" value="RIBOSOMAL_L1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0678">Repressor</keyword>
    <keyword evidence="7 8 9" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="6 8 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 8" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="4 8" id="KW-0810">Translation regulation</keyword>
    <keyword evidence="8" id="KW-0820">tRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010531"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01318"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL70880.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="239" mass="26320" checksum="86E03D46138DF563" modified="2016-01-20" version="1">MPKHGKKYLTAREKLNPGQYYTPQEAVDLVKQTSTTNFDATVEVHMRMGLDPRQADQQVRDVVVLPHGLGKTVRVLVFAQGEGVQYAEQGGADYIADTDEWIKKIQDGWFDFDVAIATPDMMGKAGRLGRVLGPRGLMPNPKAGTVVQPSDLPRVIQESKAGRVEFRLDKTANLHVPIGKVSFDADKLYENLAALMEAIKKARPSAAKGSYIRRVTVTSTMGPGIRVDANLAQSMENRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WQV0</accession>
    <name>A0A0P6WQV0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_17590</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000042">
        <property type="protein sequence ID" value="KPL71228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064376.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000042.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17590"/>
    <dbReference type="EnsemblBacteria" id="KPL71228">
        <property type="protein sequence ID" value="KPL71228"/>
        <property type="gene ID" value="ADN00_17590"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL71228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="217" mass="23674" checksum="7176598FB0B1AB62" modified="2016-01-20" version="1">MEITWYGHSCFRLTERGMATVITDPFDHSAVGYFPLKLKGDIVTCSHTAPGHSYFTAVKGEPYVITGPGEFEIGGVFITGVQTNGVHKKASENEQIRNTLYLIQFEELNIVHLGDMDRVPTQSQVESLGDVHVLLIPVGGGTGLNAAKAAEIISLLEPRIVVPMHYGVPECKIDLDPLAKFLKAMGLKEVETQPSLKIANAKALPEETQVVVLDYKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WRD1</accession>
    <name>A0A0P6WRD1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_17500</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71475.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064339.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17500"/>
    <dbReference type="EnsemblBacteria" id="KPL71475">
        <property type="protein sequence ID" value="KPL71475"/>
        <property type="gene ID" value="ADN00_17500"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.567"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043365">
        <property type="term" value="F:[formate-C-acetyltransferase]-activating enzyme activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012837">
        <property type="entry name" value="NrdG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034457">
        <property type="entry name" value="Organic_radical-activating"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30352">
        <property type="entry name" value="PTHR30352"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30352:SF2">
        <property type="entry name" value="PTHR30352:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00299">
        <property type="entry name" value="anaerobic_ribonucleoside-triph"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL71475.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="227" mass="25254" checksum="E9471E5730112E2A" modified="2016-01-20" version="1">MVTPKSRVLQYDSVLIQRGELLNVAAVCPKTRALGPGWRSAIWVQGCPFHCAGCISPEWTTFQPAHSINPVELASTLLADPEISGLTFSGGEPMQQAAGLANLARKARQQRPINIITYTGYKLEVLKKGIPDRSVFKLLDETDVLIDGQFISALNDNRGMRGSSNQRVHYLTGQLKDFNFEKAPRLSEVQVLDGQVLMVGVPEEYLLQAFYRAMWQLESLPLQLVKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WSD8</accession>
    <name>A0A0P6WSD8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CO_deh_flav_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_14955</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000036">
        <property type="protein sequence ID" value="KPL73087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063838.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000036.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14955"/>
    <dbReference type="EnsemblBacteria" id="KPL73087">
        <property type="protein sequence ID" value="KPL73087"/>
        <property type="gene ID" value="ADN00_14955"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005107">
        <property type="entry name" value="CO_DH_flav_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036683">
        <property type="entry name" value="CO_DH_flav_C_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03450">
        <property type="entry name" value="CO_deh_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01092">
        <property type="entry name" value="CO_deh_flav_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55447">
        <property type="entry name" value="SSF55447"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CO_deh_flav_C" evidence="1">
        <location>
            <begin position="120"/>
            <end position="221"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01092"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL73087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="227" mass="24137" checksum="9409AD096CFE58AF" modified="2016-01-20" version="1">MGEKTELSKVRQVQVDGLAFLLADADASLDDVEQFSGLPSLVKEGLHLGTNWHHRNEYTVEKSLLSPSLAQQWVASLLAVGAALEFEDGAKASVADLLSRRGTRGKLKALLIPMDQGAFGAEAHVGMTPGDTPIVSSTVGLVLEGGKVAALRIALAGAFKESVRLSAAAEAFLGKEFSQDLITQVADSVEEESTPKADYRGSVEYRKRMAGVLTRRALETCLKGAVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WSN7</accession>
    <name>A0A0P6WSN7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF4129 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_18045</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL69974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL69974">
        <property type="protein sequence ID" value="KPL69974"/>
        <property type="gene ID" value="ADN00_18045"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025403">
        <property type="entry name" value="DUF4129"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13559">
        <property type="entry name" value="DUF4129"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="159"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="227"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="303"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4129" evidence="2">
        <location>
            <begin position="374"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL69974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="460" mass="51804" checksum="1489C8C3720F16B2" modified="2016-01-20" version="1">MALHLLLAMYAVWVSAWYRQLVAPQASSWAMGLIWLLVLAGGYWLSRGLEKLQDRPVLQRSAALLWMVSIIFLTAFLLLFLPLRETLTMQRWMEWAFSTTENFNRVLAHLVIFGLSAWRSLDLGQRVFSREFIEKEFQLGSFALLFFGLIYSSQPSSALLIRFAAFLFLGLLALSIARIAEQEAVRGGRLPRFASIWPPLLFGLAVLISLTALLISIYAALPIASVLAQAALLLLSGLALLIILILSPVLALILEAAYRFGQKVFGDVPDLIPYSAAQQAADQMLDTGQQALDMVSTQNGRPVLFIAAVLFLIVLIFLSLRFRYYRRQLRAEEQTDRVRTARALRTERQSPTSTAASRWISPRKALAAARIRLAYARLIELSERLGHPRPPAATPAEFLPTLQLLFPDHSADLDLMTHAYQKVRYGQMPETQAEVDSVLQAWKQIQKRGNQMVKQMHAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WSP2</accession>
    <name>A0A0P6WSP2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Wzz domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">ADN00_16100</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064065.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16100"/>
    <dbReference type="EnsemblBacteria" id="KPL72014">
        <property type="protein sequence ID" value="KPL72014"/>
        <property type="gene ID" value="ADN00_16100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045226">
        <property type="term" value="P:extracellular polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009103">
        <property type="term" value="P:lipopolysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005702">
        <property type="entry name" value="EPS_synthesis"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003856">
        <property type="entry name" value="LPS_length_determ_N_term"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033756">
        <property type="entry name" value="YlxH/NBP35"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10609">
        <property type="entry name" value="ParA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02706">
        <property type="entry name" value="Wzz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01007">
        <property type="entry name" value="eps_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="domain" description="Wzz" evidence="10">
        <location>
            <begin position="22"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="350"/>
            <end position="426"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL72014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="740" mass="81207" checksum="32070971B4FB9922" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WTP9</accession>
    <name>A0A0P6WTP9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_19005</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064618.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70129">
        <property type="protein sequence ID" value="KPL70129"/>
        <property type="gene ID" value="ADN00_19005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="124" mass="13185" checksum="B7038C4B5848E4B5" modified="2016-01-20" version="1">MKAIKIIAFVIAAILILFGVIFILGAFSPQGQSSWIITGIVLLAASFGIIFFATRIHAPASDSGAAQNVTYQIDLPGSVNMDTIKCKSCGGTLTANDIKMVAGAPMVTCPYCHTSYQLTEEPKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WYA1</accession>
    <name>A0A0P6WYA1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_17160</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064277.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL71419">
        <property type="protein sequence ID" value="KPL71419"/>
        <property type="gene ID" value="ADN00_17160"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="74"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL71419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="128" mass="13973" checksum="925EF1D850BF0357" modified="2016-01-20" version="1">MAKEKKPAQPKAEAVKQPKEAKPKKEKKAKAAMPQGGVRLPRSAELVLSVSKMVVLVMGVTVFGVSLFHGVDPLMIMLRVAVTVLLLGFVFYFISWMYLRDSLDAALKPLAIEEDSSETAQTTIGKEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZX6</accession>
    <name>A0A0P6WZX6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">zinc_ribbon_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_14080</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063665.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000033.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74126">
        <property type="protein sequence ID" value="KPL74126"/>
        <property type="gene ID" value="ADN00_14080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026870">
        <property type="entry name" value="Zinc_ribbon_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13240">
        <property type="entry name" value="zinc_ribbon_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="118"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="domain" description="zinc_ribbon_2" evidence="3">
        <location>
            <begin position="8"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="103"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL74126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="148" mass="15311" checksum="B18855B356663092" modified="2016-01-20" version="1">MTSDAQICAYCGAPLSPNARFCEACGQPVSGSAPSPFEAKPASAESWSRPDAEEFPIPPMPETDRWGSVASSPADNEPQRWGSPQPITPPAPPAAPQAPYIPPAKTPTGGSSFPWKGIIIAAVVLVGLSCLCVIGAAVLFMTQTGVNY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X3H2</accession>
    <name>A0A0P6X3H2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CN hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_13665</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the carbon-nitrogen hydrolase superfamily. NIT1/NIT2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063583.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000032.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13665"/>
    <dbReference type="EnsemblBacteria" id="KPL74344">
        <property type="protein sequence ID" value="KPL74344"/>
        <property type="gene ID" value="ADN00_13665"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006807">
        <property type="term" value="P:nitrogen compound metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003010">
        <property type="entry name" value="C-N_Hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036526">
        <property type="entry name" value="C-N_Hydrolase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001110">
        <property type="entry name" value="UPF0012_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00795">
        <property type="entry name" value="CN_hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56317">
        <property type="entry name" value="SSF56317"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50263">
        <property type="entry name" value="CN_HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01227">
        <property type="entry name" value="UPF0012"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CN hydrolase" evidence="2">
        <location>
            <begin position="3"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50263"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL74344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="261" mass="29141" checksum="0BC0148FF602D724" modified="2016-01-20" version="1">MKILAAIAQTRIQFGSLTANLAITRARMQAAARLHAHWIVFPELWLHGYDLKHFSEHARGTPAALQEIAALAADYQLTVWGTVLQSEGDNLYNSLVTITPQGEIRYRYRKTHLFRPLREDSWLQAGGELAPVFTHQGISIGPAICYDLRFPELFRAQMLAGAQCVVLPAQWSRPRLEHWQTLLRARAIENQTFVIGVNAVGLTGKETLTGSSAIISPRGQVLAQASLEEEALLTAELDFDALLAWRTDFPVLKDRRGDLYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X3V4</accession>
    <name>A0A0P6X3V4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">5'-nucleotidase</fullName>
            <ecNumber evidence="3">3.1.3.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_08815</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a ribonucleoside 5'-phosphate + H2O = a ribonucleoside + phosphate</text>
            <dbReference type="Rhea" id="RHEA:12484"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:18254"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58043"/>
            <dbReference type="EC" id="3.1.3.5"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SurE nucleotidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.5" evidence="3"/>
    <dbReference type="EMBL" id="LGCL01000022">
        <property type="protein sequence ID" value="KPL77677.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062623.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000022.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08815"/>
    <dbReference type="EnsemblBacteria" id="KPL77677">
        <property type="protein sequence ID" value="KPL77677"/>
        <property type="gene ID" value="ADN00_08815"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1484"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106411">
        <property type="term" value="F:XMP 5'-nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1210.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030048">
        <property type="entry name" value="SurE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002828">
        <property type="entry name" value="SurE-like_Pase/nucleotidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036523">
        <property type="entry name" value="SurE-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30457">
        <property type="entry name" value="PTHR30457"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01975">
        <property type="entry name" value="SurE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64167">
        <property type="entry name" value="SSF64167"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00087">
        <property type="entry name" value="surE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SurE" evidence="6">
        <location>
            <begin position="9"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL77677.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="272" mass="29251" checksum="3B19EE9794A386F1" modified="2016-01-20" version="1">MATTDKKQILLTNDDGIDSPGLWAAAEALSELGYVWVAAPRDQSTGTGRSSPVTSDGRITTKTLVVHGQEWTIYSVGGTPAQVVDHCVLEILPRHPDLIVSGINYGLNIGTSIGMSGTLGAAMEGASFGIPALAASLELEDPSLVYSHSKEVDFSAAAVFVARFARQLLEKQMPFDVDVINLNIPSNATPDTPWRVTRISRHPGYDTFIERNGSLEDAARIGGNPVPVTPRDVEPDSEMYTVLFDRMVAVTPISLDCTSRVGFDDLDHLLRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X3Z0</accession>
    <name>A0A0P6X3Z0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_12225</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063298.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12225"/>
    <dbReference type="EnsemblBacteria" id="KPL76101">
        <property type="protein sequence ID" value="KPL76101"/>
        <property type="gene ID" value="ADN00_12225"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3921"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="7"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="39"/>
            <end position="46"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL76101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="259" mass="28965" checksum="407BADBA91BC596F" modified="2016-01-20" version="1">MQNKPVIHIQNLWAGYGKDPILENIQLDIYPQDFVGLIGPNGGGKTTLIKVILGLLAPARGTVEIMGLPVEQGRRFVGYVPQFVEFDRAFPISVYEVVRMGLLNKRRLLNPFKPEDHQKIMDALEQVNLAGLAQQPIGELSGGQRQRAYIARALVSQPEILLLDEPTASVDSHTSTTVFELLRELNRRVTILLISHDISAISSYVKTIGCLNRRLAYHAQKQITADMLQSTYQCPVDLIAHGLPHRVLPSHNQEELIHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X406</accession>
    <name>A0A0P6X406_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_12435</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76137.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76137">
        <property type="protein sequence ID" value="KPL76137"/>
        <property type="gene ID" value="ADN00_12435"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="56"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="86"/>
            <end position="109"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL76137.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="109" mass="12123" checksum="D13CB93366ED9ABD" modified="2016-01-20" version="1">MMEKEPVQQIDSKAYRKVVLLVTGQVGCATVLIIVLALVLGLFLDRTLNTKPLLTLVTMLVSIPVSIGSTLWILRSVLSRYQVRKSQGETGEETKFEKEEVGIGRDYEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X4J8</accession>
    <name>A0A0P6X4J8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">N_BRCA1_IG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_13400</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74829.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063528.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000031.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74829">
        <property type="protein sequence ID" value="KPL74829"/>
        <property type="gene ID" value="ADN00_13400"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032350">
        <property type="entry name" value="N_BRCA1_central"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16158">
        <property type="entry name" value="N_BRCA1_IG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132830" description="N_BRCA1_IG domain-containing protein" evidence="2">
        <location>
            <begin position="27"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="domain" description="N_BRCA1_IG" evidence="3">
        <location>
            <begin position="125"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="91"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF16158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL74829.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="220" mass="23252" checksum="473BB54A7C010E4D" modified="2016-01-20" version="1">MKQQTQKILQLALLASMLVLAGCAQATPTPEPTVDSAAIASTVSVIQTEAVMAAMQTMTQEAFLNPSATPTTPPTNTPEPTATATNTPVPTAIPVLPTSTVALPTLTPTQSEWQCSITSLDPASGREMNSGEDFDLKVTLKNTGTKTWESSNTDFLYQSGAKFQKRVDILDLESNVEPGKSVTFIVDMVANTGTGSQSAQWVLKGSGVVYCTVNINVKVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X4K6</accession>
    <name>A0A0P6X4K6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_11470</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Orn/Lys/Arg decarboxylase class-II family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063152.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11470"/>
    <dbReference type="EnsemblBacteria" id="KPL76567">
        <property type="protein sequence ID" value="KPL76567"/>
        <property type="gene ID" value="ADN00_11470"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006596">
        <property type="term" value="P:polyamine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009006">
        <property type="entry name" value="Ala_racemase/Decarboxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022643">
        <property type="entry name" value="De-COase2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022644">
        <property type="entry name" value="De-COase2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000183">
        <property type="entry name" value="Orn/DAP/Arg_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002433">
        <property type="entry name" value="Orn_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11482">
        <property type="entry name" value="PTHR11482"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02784">
        <property type="entry name" value="Orn_Arg_deC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00278">
        <property type="entry name" value="Orn_DAP_Arg_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01179">
        <property type="entry name" value="ODADCRBXLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01182">
        <property type="entry name" value="ORNDCRBXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50621">
        <property type="entry name" value="SSF50621"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="SSF51419"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orn_Arg_deC_N" evidence="3">
        <location>
            <begin position="31"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="domain" description="Orn_DAP_Arg_deC" evidence="2">
        <location>
            <begin position="265"/>
            <end position="353"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL76567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="373" mass="40678" checksum="57B87090D3E2ED12" modified="2016-01-20" version="1">MIANTPIQKLAPFLQNHTNRETPFLLIDSNRLRATCQTFLRAFSGDEVYFSMKANSTPAVLKIIAQEGIRFDAASYAEIDKLIRMGIPAEKIIFMAPTKIPADIERAYLSGVRVFSFDSAMELQKLASLAPGARVMCRVAVGNEGSEWPLERKFGASALESAALLTKAAQLGLKPLGLTFHVGSQNRNPRAWRAAIEQCAQIWYVLADQGIQLEAIDAGGGFPSNYGKDYPAVEEIAAVIHQALAQLLPPGTRLMVEPGRGLVAECGVLVTSVINRAHRAGQEWLYVDASAYHGLVEAMQGFTFPIRTEKDLAPRAPFVLCGPTCDSTDVIQENVLLPATLGLGDRLYLLTTGAYTTSMEHYNGFQFPSTVIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X502</accession>
    <name>A0A0P6X502_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09860</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76896">
        <property type="protein sequence ID" value="KPL76896"/>
        <property type="gene ID" value="ADN00_09860"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00583">
        <property type="entry name" value="Acetyltransf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N-acetyltransferase" evidence="1">
        <location>
            <begin position="11"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="291" mass="32302" checksum="4AB425BFF02BBE72" modified="2016-01-20" version="1">MLANTINMPTLTHHTLEHTPLTTIHRAFVDAFSEYEVKIEMPIEKLAEMLTTRSFSPAWSLGAFDGEAMAGFILLGARQMAGETVVYDVATGVTRAYQQQGLGDRLLKDLLARLPAWGVDSFVLEVLEHNTAAQKLYRRNGFEISRKFNCYQKSFDAPQAEQIPSSSRGAEDLRALDLPAYLSFAPSWQNALESVQNNPGQYHLEIIREGGEVHAYGIVHKQRGDVMQLGVAPACRSTAEVAGMIARLRAHTLSERLVFLNVEAGSALDRDLLALGFENTVNQYEMVYQVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X591</accession>
    <name>A0A0P6X591_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Antibiotic ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_10625</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062975.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77015">
        <property type="protein sequence ID" value="KPL77015"/>
        <property type="gene ID" value="ADN00_10625"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2599"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="7"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="39"/>
            <end position="46"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL77015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="317" mass="34558" checksum="D3B530B967659CF3" modified="2016-01-20" version="1">MDTSFAIETTGLKKSFGSLEAVSGLDLRVARGEIFSLLGPNGAGKSTSISMICGLLQPSAGRVSVCGFDLSRDPKAAKAALGVVPQDIALYPDLSARENLLFWGRMYGLGGNLLRQRVDETLEMIGLRERQNGRIGSFSGGMKRRVNIGVALLHRPQVVIMDEPTVGIDPQSRRHILDNVKELNRQGMTVLYTTHYMEEAQELSDHIAIMDHGQMIASGTHSELLRLVGEHTRVDLTVTADPAALAEAWRNIEGVAQVIPNHQVVRLMVTDSNRVLPRVFESAASLGARVQAVDIQEANLESVFLHLTGRALRDSES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5D2</accession>
    <name>A0A0P6X5D2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_18905</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064600.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18905"/>
    <dbReference type="EnsemblBacteria" id="KPL70113">
        <property type="protein sequence ID" value="KPL70113"/>
        <property type="gene ID" value="ADN00_18905"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3092"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024455">
        <property type="entry name" value="Phage_capsid"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05065">
        <property type="entry name" value="Phage_capsid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01554">
        <property type="entry name" value="major_cap_HK97"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="333" mass="36273" checksum="F1EA4FDCD9ABBE45" modified="2016-01-20" version="1">MPYNSIINRTDAEALIPEEVSREIIQEVPTSSSVMQLARKLPNMSRKQRKMPVLDALISAYFVNGDTGLKQTSEAAWTNKYVTAEEMAVIVPIPEAVLEDEDYDIWGEVKPRIVEAFGRAFDAAVVLGTNIPAAWVIDMGNHSGLLDGCTDASHVVDLSTQLAAGKDMFDVILGEGGLLSFVEEDGYEVNGHVASLTMKAKLRGVRAKVFNGVDSMVPAGEPIFVRSMQESGRYELDGTPILFPKNGAIPADSLLQVSGDWNQLVYSIRTDVTYKILTEAVIQDNTGTIIYNLAQQDMVALRAVMRLGVALPNPINAVNQDVATRFPFSALVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5H1</accession>
    <name>A0A0P6X5H1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 7">Threonylcarbamoyl-AMP synthase</fullName>
            <shortName evidence="7">TC-AMP synthase</shortName>
            <ecNumber evidence="4 7">2.7.7.87</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 7">L-threonylcarbamoyladenylate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">ADN00_07525</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>ATP + hydrogencarbonate + L-threonine = diphosphate + H2O + L-threonylcarbamoyladenylate</text>
            <dbReference type="Rhea" id="RHEA:36407"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17544"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="ChEBI" id="CHEBI:73682"/>
            <dbReference type="EC" id="2.7.7.87"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 7">Belongs to the SUA5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.87" evidence="4 7"/>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78299.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062366.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07525"/>
    <dbReference type="EnsemblBacteria" id="KPL78299">
        <property type="protein sequence ID" value="KPL78299"/>
        <property type="gene ID" value="ADN00_07525"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3331"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061710">
        <property type="term" value="F:L-threonylcarbamoyladenylate synthase"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11030">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017945">
        <property type="entry name" value="DHBP_synth_RibB-like_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038385">
        <property type="entry name" value="Sua5/YwlC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005145">
        <property type="entry name" value="Sua5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010923">
        <property type="entry name" value="T(6)A37_SUA5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006070">
        <property type="entry name" value="YrdC-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03481">
        <property type="entry name" value="SUA5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01300">
        <property type="entry name" value="Sua5_yciO_yrdC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004930">
        <property type="entry name" value="Tln_factor_SUA5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55821">
        <property type="entry name" value="SSF55821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00057">
        <property type="entry name" value="TIGR00057"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51163">
        <property type="entry name" value="YRDC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="YrdC-like" evidence="9">
        <location>
            <begin position="15"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="37"/>
        </location>
        <ligand>
            <name>L-threonine</name>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="60"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="69"/>
        </location>
        <ligand>
            <name>L-threonine</name>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="123"/>
        </location>
        <ligand>
            <name>L-threonine</name>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="143"/>
        </location>
        <ligand>
            <name>L-threonine</name>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="145"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="153"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="183"/>
        </location>
        <ligand>
            <name>L-threonine</name>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="197"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="237"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00029774"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR004930"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR004930-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL78299.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="350" mass="37437" checksum="ECA891F081C11786" modified="2016-01-20" version="1">MKTNVLTVHSQNPEHAVIAEAARVIQSGRLAAFPTETVYGLGANALDVQAVLRIFAAKGRPSHDPLIVHIADLSMLEQVARDVPEEARLLAEHFWPGPLTLILPKHANIPAEVTAGLENVAVRMPAHPVALALIRAAGLPVAAPSANRFGHTSPTSAAHVLADLDGRIDLILDGGSTQIGVESTVLDVSQSPARILRPGGVSYEALCEVLENVMINGQKASPDNLPQLSPGMLSRHYAPHAVMILYESDGDARVCAEMQEKVTGLLAEGKQVGVICAVEDLIYFEGTNAVVRLVGSVEHLEEIARNLYLALRDLDAAGMDYIVAREFGSQGIGLAIQDRLRRAATIKEQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5J3</accession>
    <name>A0A0P6X5J3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Usp domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_13120</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the universal stress protein A family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000029">
        <property type="protein sequence ID" value="KPL75295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL75295">
        <property type="protein sequence ID" value="KPL75295"/>
        <property type="gene ID" value="ADN00_13120"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006015">
        <property type="entry name" value="Universal_stress_UspA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006016">
        <property type="entry name" value="UspA"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00582">
        <property type="entry name" value="Usp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01438">
        <property type="entry name" value="UNVRSLSTRESS"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="24"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="106"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="151"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="226"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="259"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="284"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="domain" description="Usp" evidence="7">
        <location>
            <begin position="466"/>
            <end position="594"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008791"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00582"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL75295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="613" mass="67537" checksum="A717E0BE38FB7533" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5M4</accession>
    <name>A0A0P6X5M4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_07385</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07385"/>
    <dbReference type="EnsemblBacteria" id="KPL78353">
        <property type="protein sequence ID" value="KPL78353"/>
        <property type="gene ID" value="ADN00_07385"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3299"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901137">
        <property type="term" value="P:carbohydrate derivative biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030259">
        <property type="term" value="P:lipid glycosylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007235">
        <property type="entry name" value="Glyco_trans_28_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004276">
        <property type="entry name" value="GlycoTrans_28_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04101">
        <property type="entry name" value="Glyco_tran_28_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03033">
        <property type="entry name" value="Glyco_transf_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_transf_28" evidence="3">
        <location>
            <begin position="2"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="Glyco_tran_28_C" evidence="4">
        <location>
            <begin position="146"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF04101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL78353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="333" mass="36274" checksum="2AF6E68B6FE2B5A5" modified="2016-01-20" version="1">MEADLVARLGVAYQSIPAAGVHGVSLLRLPGNLWKLFQGWLASRRILREFKPDVLLLTGGYLAVPMAIAARRVPTLLYVPDIEPGLALKTLARFADRIAVTAEDSRAFFQPSAPIVETGYPTRPELAAWERAAALRHLGLSDDSPVLLVFGGSKGARTINRALLSILEDLLARVQVVHISGSLDWEEVQAARQNLPAHLQPRYHAFPYLHEDMGAALASADLVVSRAGASSLGEYPLFGLPAILVPYPYAWRYQKVNAEYLASRGAALLLRDEHMPQQLHALITQLLDDPQKLQAMRAAMRSLALPNPAQKISSLLSELAGEKPISGGEHGRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X645</accession>
    <name>A0A0P6X645_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_13350</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063519.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000031.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13350"/>
    <dbReference type="EnsemblBacteria" id="KPL74823">
        <property type="protein sequence ID" value="KPL74823"/>
        <property type="gene ID" value="ADN00_13350"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="4"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="127"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="127"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL74823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="229" mass="26053" checksum="4401763D4980ECB8" modified="2016-01-20" version="1">MTRKILVVDDTRNVQVMISDFLTGQDFTLLTASDGREALQVVHEASPDLILLDIMMPNMDGYQFISQLRRESSIPVIMITAKQQEADIIHGFDLGADDYITKPFRLRELLVRMRAVLRRAAPCEESKPLLSCGDITLDPGKHEVRKQGRVIELTPLEFNILEILLHSSGQVVRRADLSMRLMESGFTGSEATLKIHIRNLRLKLEDDLEQPRYIETIFGIGYRFVEAAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7I1</accession>
    <name>A0A0P6X7I1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">2-dehydropantoate 2-reductase</fullName>
            <ecNumber evidence="2">1.1.1.169</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Ketopantoate reductase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_08505</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>(R)-pantoate + NADP(+) = 2-dehydropantoate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:16233"/>
            <dbReference type="ChEBI" id="CHEBI:11561"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15980"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.169"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Cofactor biosynthesis; (R)-pantothenate biosynthesis; (R)-pantoate from 3-methyl-2-oxobutanoate: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the ketopantoate reductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.169" evidence="2"/>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77920.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08505"/>
    <dbReference type="EnsemblBacteria" id="KPL77920">
        <property type="protein sequence ID" value="KPL77920"/>
        <property type="gene ID" value="ADN00_08505"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00028">
        <property type="reaction ID" value="UER00004"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008677">
        <property type="term" value="F:2-dehydropantoate 2-reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1040.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008927">
        <property type="entry name" value="6-PGluconate_DH-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013328">
        <property type="entry name" value="6PGD_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003710">
        <property type="entry name" value="ApbA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013752">
        <property type="entry name" value="KPA_reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013332">
        <property type="entry name" value="KPR_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02558">
        <property type="entry name" value="ApbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08546">
        <property type="entry name" value="ApbA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48179">
        <property type="entry name" value="SSF48179"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00745">
        <property type="entry name" value="apbA_panE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="2" id="KW-0566">Pantothenate biosynthesis</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ApbA" evidence="3">
        <location>
            <begin position="6"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="domain" description="ApbA_C" evidence="4">
        <location>
            <begin position="179"/>
            <end position="316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007870"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU362068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08546"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL77920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="340" mass="36440" checksum="15ACD4547561BAAD" modified="2016-01-20" version="1">MRFLCFGAGAIGTYIGGSLALAGQEVVFFDRPETADSVRKHGLTLHLGDEVRHIQSIDICTSIDEALTHGPFDVGILAVKSYDTAGVIEMLKEYSVALPPILSFQNGVENEALLSRGLGQGKVIAGTLTSAVGKLQTGEIVVEKLRGIGVASDHLLASGLVKVLDAAGLRAQLFADAASMKWSKMLTNLPANATSAILNMTASEIYRNRDLCKLEIRMLREALAVMHTLRLSVVDLPGTPTRLLAFGAASLPLFLAQPFMIQGIGKGRGNKMPSFHIDFHSGNGKSEVDYLNGAVVRIGKSVGVEAPVNRVLTETLLLLTAGELNADEFDHHPEKLLERF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X844</accession>
    <name>A0A0P6X844_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">NAD-dependent dehydratase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_07000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062268.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78222">
        <property type="protein sequence ID" value="KPL78222"/>
        <property type="gene ID" value="ADN00_07000"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3217"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="4"/>
            <end position="215"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="341" mass="38097" checksum="3878E56C6191A871" modified="2016-01-20" version="1">MKVLFIGGTGNISASVSRLAVEQGIQLYLLTRGQTPVHIPGARVLTGDIQNVSHVQELLSGHQFDAVVNWINYTQDQVERDVHLFAGRTRQYIFISSASAYQKPVLNPIITEQTPLENPYWEYSRNKIACENYLMDAFHNASFPATIVRPSHTYDTILPLVLGGGATFTLADRILRGQPVILHGDGSSLWTLTHSQDFARAFLRLLGNTAAIGEAFHITSDESLTWNQIYLALSEALGVKARVVHVPSDFIARVVPDRGPSLLGDKAWSVIFDNTKIKQFVPGWQAVIAFRDGIRATLNWFQADARRMVIDPKINQDTEKILAAYRRAYDDPEEIISGWQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X879</accession>
    <name>A0A0P6X879_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_07315</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78268">
        <property type="protein sequence ID" value="KPL78268"/>
        <property type="gene ID" value="ADN00_07315"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="177" mass="17864" checksum="38B6C46A81D1762F" modified="2016-01-20" version="1">MTGGLVGTGVGLGGGAWVGGGLVGAGGCVGREVGALVGGLTGVLEDPLTGMGAVAVRLSTTNVLPGRQVGVKVLKRVGVGLNKEPPGVLVGWKKRGVAISPPDSSGCPSDVAMTATDCCVAEEIRVGVRVTNSLICPVGLEASALTIKTANNPARIPKIPPNRIFRFFIAALLYYLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X8C8</accession>
    <name>A0A0P6X8C8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">von Willebrand factor A</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_04850</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Mg-chelatase subunits D/I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061898.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04850"/>
    <dbReference type="EnsemblBacteria" id="KPL79249">
        <property type="protein sequence ID" value="KPL79249"/>
        <property type="gene ID" value="ADN00_04850"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.337"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd01451">
        <property type="entry name" value="vWA_Magnesium_chelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.410">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041702">
        <property type="entry name" value="BchD/ChlD_VWA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002035">
        <property type="entry name" value="VWF_A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036465">
        <property type="entry name" value="vWFA_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13519">
        <property type="entry name" value="VWA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00327">
        <property type="entry name" value="VWA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53300">
        <property type="entry name" value="SSF53300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50234">
        <property type="entry name" value="VWFA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VWFA" evidence="2">
        <location>
            <begin position="78"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="270" mass="30385" checksum="45B926B2D84177BF" modified="2016-01-20" version="1">MLRRGSGRRSVTYTKLKRGRYIQARPAQGKTFDLAFDATLRAAAPFQKERKQQREKVAFAVRPGDYMKKIRVRRAANLVLFLVDASWSMAVTERMQATKGAILSLLTDAYQRRDRVGLITFQKDRATLILAPTNSVNLAQRALADIPVGGKTPLSSGLKMAHDVLEREKNLHPDIMPLLIVLTDGAANVTMGYLPPQEEAYRIADLIAEKLIHTVVVNLENTTFDQGYAQQLADHLHGPCYQISDLRAETLYLTVRKEMNQLRAPDDKIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X907</accession>
    <name>A0A0P6X907_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SBP_bac_5 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_11880</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063233.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11880"/>
    <dbReference type="EnsemblBacteria" id="KPL76048">
        <property type="protein sequence ID" value="KPL76048"/>
        <property type="gene ID" value="ADN00_11880"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042597">
        <property type="term" value="C:periplasmic space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030678">
        <property type="entry name" value="Peptide/Ni-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039424">
        <property type="entry name" value="SBP_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000914">
        <property type="entry name" value="SBP_5_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30290">
        <property type="entry name" value="PTHR30290"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00496">
        <property type="entry name" value="SBP_bac_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002741">
        <property type="entry name" value="MppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SBP_bac_5" evidence="1">
        <location>
            <begin position="85"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="562" mass="62964" checksum="587C75585840FE15" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X952</accession>
    <name>A0A0P6X952_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">tRNA pseudouridine synthase A</fullName>
            <ecNumber evidence="4">5.4.99.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridine(38-40) synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA pseudouridylate synthase I</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">tRNA-uridine isomerase I</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">truA</name>
        <name evidence="9" type="ORF">ADN00_12460</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Formation of pseudouridine at positions 38, 39 and 40 in the anticodon stem and loop of transfer RNAs.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4 7">
            <text>uridine(38/39/40) in tRNA = pseudouridine(38/39/40) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:22376"/>
            <dbReference type="Rhea" id="RHEA-COMP:10085"/>
            <dbReference type="Rhea" id="RHEA-COMP:10087"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="EC" id="5.4.99.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="4">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 7">Belongs to the tRNA pseudouridine synthase TruA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.4.99.12" evidence="4"/>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76140.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063342.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12460"/>
    <dbReference type="EnsemblBacteria" id="KPL76140">
        <property type="protein sequence ID" value="KPL76140"/>
        <property type="gene ID" value="ADN00_12460"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3973"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0106029">
        <property type="term" value="F:tRNA pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031119">
        <property type="term" value="P:tRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd02570">
        <property type="entry name" value="PseudoU_synth_EcTruA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.580">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.660">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00171">
        <property type="entry name" value="TruA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001406">
        <property type="entry name" value="PsdUridine_synth_TruA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020097">
        <property type="entry name" value="PsdUridine_synth_TruA_a/b_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020095">
        <property type="entry name" value="PsdUridine_synth_TruA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020094">
        <property type="entry name" value="TruA/RsuA/RluB/E/F_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11142">
        <property type="entry name" value="PTHR11142"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01416">
        <property type="entry name" value="PseudoU_synth_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF001430">
        <property type="entry name" value="tRNA_psdUrid_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="SSF55120"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00071">
        <property type="entry name" value="hisT_truA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4 7" id="KW-0413">Isomerase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4 7" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="PseudoU_synth_1" evidence="8">
        <location>
            <begin position="9"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="PseudoU_synth_1" evidence="8">
        <location>
            <begin position="144"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="4 5">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4 6">
        <location>
            <position position="111"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR001430-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR001430-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL76140.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="259" mass="29299" checksum="50CB74D14D3FFDA2" modified="2016-01-20" version="1">MARYQVTLAYDGTHFYGFQRQEERARTVQAEVEAALRRIGWQDRTILAAGRTDTGVHASGQVIAFDFDWRHSPEALGRAMNSNLPSDVAVRAIAVARDDFHPRYDATARTYRYQIFCEAERDPLRERYSWRVWPAVDCDLLQSAARLLTGTHDFAAFGSPPREQGSTIRTVYRAGWRMLAGGLQLEITANAFLYHMVRRLVFWSVLAGQRMLSLQAFEHAIEAAQPQTPGLAPPQGLNLYQVCYSLDGLKSEVTKSDEI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X976</accession>
    <name>A0A0P6X976_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7 8">Translation initiation factor IF-2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">infB</name>
        <name evidence="10" type="ORF">ADN00_02700</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7 8">One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7 8">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. IF-2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000012">
        <property type="protein sequence ID" value="KPL79441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061420.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000012.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02700"/>
    <dbReference type="EnsemblBacteria" id="KPL79441">
        <property type="protein sequence ID" value="KPL79441"/>
        <property type="gene ID" value="ADN00_02700"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2368"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03702">
        <property type="entry name" value="IF2_mtIF2_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10050">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00100_B">
        <property type="entry name" value="IF_2_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044145">
        <property type="entry name" value="IF2_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006847">
        <property type="entry name" value="IF2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000178">
        <property type="entry name" value="TF_IF2_bacterial-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015760">
        <property type="entry name" value="TIF_IF2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023115">
        <property type="entry name" value="TIF_IF2_dom3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036925">
        <property type="entry name" value="TIF_IF2_dom3_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43381">
        <property type="entry name" value="PTHR43381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11987">
        <property type="entry name" value="IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04760">
        <property type="entry name" value="IF2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="SSF50447"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52156">
        <property type="entry name" value="SSF52156"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00487">
        <property type="entry name" value="IF-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01176">
        <property type="entry name" value="IF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6 7" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3 7 8" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5 7 8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="9">
        <location>
            <begin position="95"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="G-domain" evidence="7">
        <location>
            <begin position="98"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="104"/>
            <end position="111"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="150"/>
            <end position="154"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="204"/>
            <end position="207"/>
        </location>
        <ligand>
            <name>GTP</name>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00020675"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00100"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU000644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL79441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="594" mass="64489" checksum="CAED8CCE7DA96098" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9D4</accession>
    <name>A0A0P6X9D4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09655</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062794.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76859">
        <property type="protein sequence ID" value="KPL76859"/>
        <property type="gene ID" value="ADN00_09655"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="154" mass="17575" checksum="6E3F9DC1DEDBA769" modified="2016-01-20" version="1">MNLTIHSLSTESDFFRARNFLREVFLANERLEHSWTVARLDYWRWHFIATCQFTRPFDQVMVGWQTATGELAAVMHAFGFGEIRAHIHPRYRSAALEDEMFSYAEQHYSTTPMRLKTGSESSSRYSPMTLCGSRSSPRADSANTLAGITITGAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9P5</accession>
    <name>A0A0P6X9P5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein-L-isoaspartate O-methyltransferase</fullName>
            <ecNumber evidence="2">2.1.1.77</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">L-isoaspartyl protein carboxyl methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Protein L-isoaspartyl methyltransferase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="2">Protein-beta-aspartate methyltransferase</fullName>
            <shortName evidence="2">PIMT</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">pcm</name>
        <name evidence="3" type="ORF">ADN00_17645</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Catalyzes the methyl esterification of L-isoaspartyl residues in peptides and proteins that result from spontaneous decomposition of normal L-aspartyl and L-asparaginyl residues. It plays a role in the repair and/or degradation of damaged proteins.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2">
            <text>[protein]-L-isoaspartate + S-adenosyl-L-methionine = [protein]-L-isoaspartate alpha-methyl ester + S-adenosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:12705"/>
            <dbReference type="Rhea" id="RHEA-COMP:12143"/>
            <dbReference type="Rhea" id="RHEA-COMP:12144"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:90596"/>
            <dbReference type="ChEBI" id="CHEBI:90598"/>
            <dbReference type="EC" id="2.1.1.77"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2">Belongs to the methyltransferase superfamily. L-isoaspartyl/D-aspartyl protein methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.77" evidence="2"/>
    <dbReference type="EMBL" id="LGCL01000042">
        <property type="protein sequence ID" value="KPL71223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064372.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000042.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17645"/>
    <dbReference type="EnsemblBacteria" id="KPL71223">
        <property type="protein sequence ID" value="KPL71223"/>
        <property type="gene ID" value="ADN00_17645"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2795"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004719">
        <property type="term" value="F:protein-L-isoaspartate (D-aspartate) O-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030091">
        <property type="term" value="P:protein repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00090">
        <property type="entry name" value="PIMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000682">
        <property type="entry name" value="PCMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11579">
        <property type="entry name" value="PTHR11579"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00080">
        <property type="entry name" value="pimt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01279">
        <property type="entry name" value="PCMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 3" id="KW-0808">Transferase</keyword>
    <feature type="active site" evidence="2">
        <location>
            <position position="68"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005369"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00090"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL71223.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="223" mass="24277" checksum="04D70E81A7ABEA28" modified="2016-01-20" version="1">MKTLEEPEILREAREKMVHSQIELRGIQNAAVLAAMRAVPRHVFVPSELVEEAYDDCPLPIGEGQTISQPYIVGLMTTLLRPRAGQRILEVGTGSGYQAAVLAQMVGDVYTLERIGSLAARAAQLFERLELGNVHVQQGDGCLGWPEAAPFDGIILTAGAPQIPQPLFDQLAEGGRLVGPVGSRFHQMLQVWVKEGGRLEGEDTIAVAFVPLRGQFGWGAEEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9X7</accession>
    <name>A0A0P6X9X7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ABC2_membrane domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_06545</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78862.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06545"/>
    <dbReference type="EnsemblBacteria" id="KPL78862">
        <property type="protein sequence ID" value="KPL78862"/>
        <property type="gene ID" value="ADN00_06545"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC_2_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="59"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="93"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="126"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="182"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="ABC2_membrane" evidence="6">
        <location>
            <begin position="2"/>
            <end position="174"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01061"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL78862.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="214" mass="24236" checksum="96D7381059B68AFA" modified="2016-01-20" version="1">MVILAFVFSTIYNVPFADFGIYIFSGLLPWQLMSNSIIGGTMSIIYAEGYLKKVYTPKILFPLVTVSTEAVNFSLSLFSLFILAFLLGAKIGVSLLFLPFAIIITFLFVLGIVLVVSVATIYFRDLYNIVQVVFTALFYLVPVVYKISIIPENYQVFYKLNPFFYFIDLFHKIIYESIIPSAAHWGVCLGLSLVALLLGLFILNLKEQDLIFRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XA09</accession>
    <name>A0A0P6XA09_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Zinc-hook domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_16940</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064235.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16940"/>
    <dbReference type="EnsemblBacteria" id="KPL71388">
        <property type="protein sequence ID" value="KPL71388"/>
        <property type="gene ID" value="ADN00_16940"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038729">
        <property type="entry name" value="Rad50/SbcC_AAA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013134">
        <property type="entry name" value="Zn_hook_RAD50"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13476">
        <property type="entry name" value="AAA_23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51131">
        <property type="entry name" value="ZN_HOOK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1 4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Zinc-hook" evidence="6">
        <location>
            <begin position="378"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="192"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="323"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="455"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="558"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="658"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="425"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="428"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51131"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL71388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="855" mass="97567" checksum="F93D928CF7F1DE4F" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XA64</accession>
    <name>A0A0P6XA64_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">N_BRCA1_IG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_03455</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78963.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03455"/>
    <dbReference type="EnsemblBacteria" id="KPL78963">
        <property type="protein sequence ID" value="KPL78963"/>
        <property type="gene ID" value="ADN00_03455"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd14947">
        <property type="entry name" value="NBR1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032350">
        <property type="entry name" value="N_BRCA1_central"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16158">
        <property type="entry name" value="N_BRCA1_IG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="N_BRCA1_IG" evidence="2">
        <location>
            <begin position="95"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78963.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="335" mass="35748" checksum="C5B714C39E0D23C5" modified="2016-01-20" version="1">MIVRQMSTSVHLFWTGKPILLAQLSCLLFLASCSMPAGEVPMPAGLPTPTAAAIPNPVTAGDETQPDLSPTPPPSAHVPREGLYLAQPGNPIDVTVPDGTPLRPGEPFTKTWRLVNVGLESWTPEFALVWFSGDTMSLYKEQSLRVVVAPGEALELSVEMIAPEKPGSYQSNWKLRAADGTLFGLGPHGNSPFWAKIQVEDIGMASAAAASPTPQATTVINGYIRLNPSDELDFDGVEPVADAMTDVKFVVDGDSGAQLSPVNGARISIFGSRIPTYDECVSSLLFADSIGLVLSDAPAYICFYTDQKIPGYASLDLSQIDVNVLVLTYATWDIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAF2</accession>
    <name>A0A0P6XAF2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HTH lacI-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_04205</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79081.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061708.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79081">
        <property type="protein sequence ID" value="KPL79081"/>
        <property type="gene ID" value="ADN00_04205"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00036">
        <property type="entry name" value="HTHLACI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="5"/>
            <end position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL79081.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="337" mass="36890" checksum="58A618D99BA0D955" modified="2016-01-20" version="1">MPKRVTIAEVAKEAGVSIATVSRVLNQRSGKIKISQETDLAVRLAASRLGYQADPFAVALRSRRSGLFGAIIRDIRDPFLVKLYTHMQKHARSNGIELLLGHADYNLAVAGRQANIMGSLWFDALILLGDIPGDRSMIQHLKIYHKPCVAVACGQMEGIPSINIDEKAGTYLALDHLYSLGHRRIACVGDPNAIGIQERLVHFKEYASAHQLTVEEGYFQVCANQRLEAASCAERLMRLPNPPTAIFCGSDVMALGVLNQLHRIGAKSVSVIGFDDIDESAQVFPALTTIRQPVQVFAEKAILLALEMMDEPEGKTSAPQILIQPELVVRESCFPVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAP0</accession>
    <name>A0A0P6XAP0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_04925</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061839.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79191">
        <property type="protein sequence ID" value="KPL79191"/>
        <property type="gene ID" value="ADN00_04925"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="3">
        <location>
            <begin position="22"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="4">
        <location>
            <begin position="130"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="91"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL79191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="204" mass="23417" checksum="2C378B6F9F16D43F" modified="2016-01-20" version="1">MINEAALAQAAKDGDLNAFNRLILEYQDMAYNVAYRLLSDPDGASDALQEAVISAYRSLQQYRGGSFKAWLLRMVTNKCYDELRRRKRRPTVPLEPFDPESEEELENPSWLADESPSTEEQIEEMDLEKAVQDCINHLPDEFRAVVVLVDLQAMDYQEASDAIGKPLGTIKSRLARARLKLRDCLQRFGELLPSMFRLEEEETR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAY6</accession>
    <name>A0A0P6XAY6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_10045</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062868.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10045"/>
    <dbReference type="EnsemblBacteria" id="KPL76926">
        <property type="protein sequence ID" value="KPL76926"/>
        <property type="gene ID" value="ADN00_10045"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007530">
        <property type="entry name" value="Aminoglycoside_adenylylTfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04439">
        <property type="entry name" value="Adenyl_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="132" mass="14757" checksum="34F8B7C2DA9A8523" modified="2016-01-20" version="1">MSVSPFLLNFTAWAQSQPDVLAAALVGSHARGTASPTSDVDLVILARDPQRYLNDQSWVNRFGELLCSQMEDYGRLTSLRVWYQSGLEVEFGLTGADWAARPLDAGTRRVIEDGMRVLFERQPLLSPFQPIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XB07</accession>
    <name>A0A0P6XB07_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_03145</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000014">
        <property type="protein sequence ID" value="KPL79337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061506.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000014.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79337">
        <property type="protein sequence ID" value="KPL79337"/>
        <property type="gene ID" value="ADN00_03145"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="40"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="191"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="218" mass="22047" checksum="F4186D0FE7F25DCD" modified="2016-01-20" version="1">MSDFNDNIFDDFEEEPSNQPEPVFEDEEPPQPKRGQNRTFVIAVGVLGAIFLLILIAMAVFALIIVPQRNAAMAEQAAQINAANTATSVAATEGAFAQAMAATGTAQFVPSPTGTATQTPVVVFSTQTPEPEAGGDGIGAGADLNARTATVSALLTLAAGGGTTPNATQATQTAAAKTPTALPTTGFADEVGLPGLLGVAVLLVAVIALSRRLRAAAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XB39</accession>
    <name>A0A0P6XB39_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Hemerythrin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10215</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062900.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76953">
        <property type="protein sequence ID" value="KPL76953"/>
        <property type="gene ID" value="ADN00_10215"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012312">
        <property type="entry name" value="Hemerythrin-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01814">
        <property type="entry name" value="Hemerythrin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Hemerythrin" evidence="1">
        <location>
            <begin position="14"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="217" mass="24575" checksum="039913660E58A2BB" modified="2016-01-20" version="1">MSQSGAPNVGNDLIRIHHAITRGLEVGVHYTHKLLEKRMAADSGFVDYLRALVSVLDSHHLVEDDVAFPYLRQKNLPAPYEILIQEHQEMAGLLSSIQQMLPNLANSQTLNEVNRALQQILEIWRAHIKREEESISPEITNTIMSAEEQAELGKSMAQHAQQHSGPDYLVIPFVLYNLPAQERAVMMGLMPPVITQELLPGPWKEKWAAMRPYLLMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XC48</accession>
    <name>A0A0P6XC48_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Citrate synthase (unknown stereospecificity)</fullName>
            <ecNumber evidence="3">2.3.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_09410</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Carbohydrate metabolism; tricarboxylic acid cycle.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 5">Belongs to the citrate synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.3.16" evidence="3"/>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09410"/>
    <dbReference type="EnsemblBacteria" id="KPL77365">
        <property type="protein sequence ID" value="KPL77365"/>
        <property type="gene ID" value="ADN00_09410"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4116"/>
    <dbReference type="UniPathway" id="UPA00223"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036440">
        <property type="term" value="F:citrate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.580.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016142">
        <property type="entry name" value="Citrate_synth-like_lrg_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016143">
        <property type="entry name" value="Citrate_synth-like_sm_a-sub"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002020">
        <property type="entry name" value="Citrate_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019810">
        <property type="entry name" value="Citrate_synthase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036969">
        <property type="entry name" value="Citrate_synthase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11739">
        <property type="entry name" value="PTHR11739"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00285">
        <property type="entry name" value="Citrate_synt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00143">
        <property type="entry name" value="CITRTSNTHASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48256">
        <property type="entry name" value="SSF48256"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00480">
        <property type="entry name" value="CITRATE_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010566"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003406"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL77365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="432" mass="48289" checksum="101DCD4C59B74998" modified="2016-01-20" version="1">MAAIIPAHRARVTKLVRSHGSFVVDQVTIDRLYGGLRGMTVLVSEISKVDPQYGIRLRGYTIQEVLDLLPKAPGTEYPLAGGLYYLLLMGEMPTLEDALMVENEWKARSHVPDYVFNVLKSLPADTHPMTMFSQAILSMQHESVFARRYNEDLQKVDYWEAALEDSLNLTAKLPTIAAFIYNLRYRDGQFISPDPNLDWSANFGHMIGKGKDSDYLELCRLFFVLHSDHEGANVSAHTAHLVGSTLSDIYYSCSAGINGLAGPLHGLANQKCLRWLLSVRESFESFPTRDQLEKFASDTLNAGKVIPGYGHAVLRTVDPRFTAQLKFADKYLPQDELFKLVKLVYEVVPDVLQKTGKVKNPWPNVDAINGTLQYHYGVKEFEFYTVLFGVGRIMGITANNVWARALGLPIERPVSLTTGNLEELTAGISSQI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XCD9</accession>
    <name>A0A0P6XCD9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01915</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000007">
        <property type="protein sequence ID" value="KPL80051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061274.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000007.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80051">
        <property type="protein sequence ID" value="KPL80051"/>
        <property type="gene ID" value="ADN00_01915"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="215"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="293"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="334"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="368"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="395"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="669" mass="75538" checksum="29D102A256998EFE" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XD54</accession>
    <name>A0A0P6XD54_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4 5">Acylphosphatase</fullName>
            <ecNumber evidence="3 4 5">3.6.1.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_01235</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 4 5">
            <text>an acyl phosphate + H2O = a carboxylate + H(+) + phosphate</text>
            <dbReference type="Rhea" id="RHEA:14965"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29067"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:59918"/>
            <dbReference type="EC" id="3.6.1.7"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the acylphosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.1.7" evidence="3 4 5"/>
    <dbReference type="EMBL" id="LGCL01000003">
        <property type="protein sequence ID" value="KPL80840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061143.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01235"/>
    <dbReference type="EnsemblBacteria" id="KPL80840">
        <property type="protein sequence ID" value="KPL80840"/>
        <property type="gene ID" value="ADN00_01235"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1995"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003998">
        <property type="term" value="F:acylphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020456">
        <property type="entry name" value="Acylphosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001792">
        <property type="entry name" value="Acylphosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036046">
        <property type="entry name" value="Acylphosphatase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017968">
        <property type="entry name" value="Acylphosphatase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47268">
        <property type="entry name" value="PTHR47268"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00708">
        <property type="entry name" value="Acylphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00112">
        <property type="entry name" value="ACYLPHPHTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54975">
        <property type="entry name" value="SSF54975"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00150">
        <property type="entry name" value="ACYLPHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00151">
        <property type="entry name" value="ACYLPHOSPHATASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51160">
        <property type="entry name" value="ACYLPHOSPHATASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acylphosphatase-like" evidence="7">
        <location>
            <begin position="9"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="24"/>
        </location>
    </feature>
    <feature type="active site" evidence="4">
        <location>
            <position position="42"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000744"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012150"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL80840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="98" mass="11113" checksum="BB8343C5853DD193" modified="2016-01-20" version="1">MTKSQLEKRLHATVEGQVQGVGFRYFVLEAAQALNLVGWVRNTYRGEVELVAEGAQEQLDRLLRLVQRGPSMSYVANVRVSWEEPTGDYDRFQVVASL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDN8</accession>
    <name>A0A0P6XDN8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Histidine ammonia-lyase</fullName>
            <ecNumber evidence="3 6">4.3.1.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_00040</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>L-histidine = NH4(+) + trans-urocanate</text>
            <dbReference type="Rhea" id="RHEA:21232"/>
            <dbReference type="ChEBI" id="CHEBI:17771"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57595"/>
            <dbReference type="EC" id="4.3.1.3"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 6">Amino-acid degradation; L-histidine degradation into L-glutamate; N-formimidoyl-L-glutamate from L-histidine: step 1/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the PAL/histidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.1.3" evidence="3 6"/>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL80983.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060912.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00040"/>
    <dbReference type="EnsemblBacteria" id="KPL80983">
        <property type="protein sequence ID" value="KPL80983"/>
        <property type="gene ID" value="ADN00_00040"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3404"/>
    <dbReference type="UniPathway" id="UPA00379">
        <property type="reaction ID" value="UER00549"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004397">
        <property type="term" value="F:histidine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019556">
        <property type="term" value="P:histidine catabolic process to glutamate and formamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019557">
        <property type="term" value="P:histidine catabolic process to glutamate and formate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00332">
        <property type="entry name" value="PAL-HAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001106">
        <property type="entry name" value="Aromatic_Lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005921">
        <property type="entry name" value="HutH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022313">
        <property type="entry name" value="Phe/His_NH3-lyase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10362">
        <property type="entry name" value="PTHR10362"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00221">
        <property type="entry name" value="Lyase_aromatic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01225">
        <property type="entry name" value="hutH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00488">
        <property type="entry name" value="PAL_HISTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0369">Histidine metabolism</keyword>
    <keyword evidence="5" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000171"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022808"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003954"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL80983.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="508" mass="55145" checksum="EE6C53E2E49214D3" modified="2016-01-20" version="1">MVQIDGYHLTSADVIRVAREFEPVQISEEGKRQVCESRRRLENLLKIDRAVYGINTGFGIFADQMIPNRASARLSRNLILSHSVGAGEPLPDEVVRAAMLVRANTLAKGFSGVRLEIVETLVNMLNSGVTPVVPSQGSLGSSGDLCPLSHLALVFTTDDADREEDSGQAWYQGKLMSGKAAMQAAGIERLVLGAKEGLALNNGATVSAALAALAVEDADYLLKVGDVSLSMSLEAVLGCSAAFDERLHAVRGHTGQMAVAERVRSLTKGSHLVDASGRIQDAYSLRCAPQVQGAARDTLEFVQKVVEREINAATDNPLIFSDEEVLSGGNFHGEPVGMAMDYLGVAISELASISERRIFRLTDSKLNYGLPPMLVDNIEAAGLNSGMMIPQYTAASLVLENQTLASPDSVHSLPTSAEQEDHNANSMTAARHTRLILQNTTHVLAIELYTAARALDLRLRQIPERRLGQGTYAAYRKIRQEVPYQPGDAWWGPEIDRVKQMIIKRDFE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDP2</accession>
    <name>A0A0P6XDP2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_00090</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL80992.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060922.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00090"/>
    <dbReference type="EnsemblBacteria" id="KPL80992">
        <property type="protein sequence ID" value="KPL80992"/>
        <property type="gene ID" value="ADN00_00090"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="35"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80992.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="210" mass="23385" checksum="0B5F316EBB04EEBE" modified="2016-01-20" version="1">MEEIERVLNADSRLQKAALNVEKSKKEIHLAQVSIRGIEETIREINVKIEISEKNLYGGSVRNPKELQDLQNEIASLKRQRSNLEDNQLAEMIRFEELEMQSQADQAQYSEILTLVTSESSALAGEKTASLATVERLLVERAGLLHSIPAESLRLYEDLCKSKKGRAIAKIDEDSCSECGAPIRPSLIQAARSRLTLAYCPSCGRILFAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XEL4</accession>
    <name>A0A0P6XEL4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_14760</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000035">
        <property type="protein sequence ID" value="KPL73597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063798.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000035.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL73597">
        <property type="protein sequence ID" value="KPL73597"/>
        <property type="gene ID" value="ADN00_14760"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2118"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000620">
        <property type="entry name" value="EamA_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00892">
        <property type="entry name" value="EamA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="123"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="211"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="243"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="268"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="9"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="EamA" evidence="2">
        <location>
            <begin position="152"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00892"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL73597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="293" mass="31718" checksum="019A8116EEAA45B4" modified="2016-01-20" version="1">MTFRDWVKFIVLSLLWGSSFLWIKIAVQEIGPFTLVAFRILFGLLGFLVFFLLTRPALPSRAYIGPFALMGLFNIAVPFVLISWSEKFIPSGMASVLNSTTPLWAIVISPFFIAEDRLTVKKVLGLVLGFGGVVMLVSNQLTGGVGHQAIAPLTMLAATFCYAITAVYSRLKLAGLDPIAQTAGAFTGAALAIVPSAMIVEAPFQLPQLPITWLALAWLGLLGTFTAYMLYYSLIHSIGPMRATSVTYVMALVGVVLGILFLSEPPDWRLFAGGALIIGGVMLVNQKKRELAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XEY1</accession>
    <name>A0A0P6XEY1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05745</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ROK (NagC/XylR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062013.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05745"/>
    <dbReference type="EnsemblBacteria" id="KPL78742">
        <property type="protein sequence ID" value="KPL78742"/>
        <property type="gene ID" value="ADN00_05745"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="395" mass="42976" checksum="7B726B8B6566D30B" modified="2016-01-20" version="1">MHQIITSSGMRSINQSAILEIIRSESPTSRTYISQKLGISLPTVMRIVDELVDLGFVRNTEETEWSGGRRRPLLEFNAQGNAVIGIDLGGGTMFGAIADIGGNLLAELDIPFATIPQEKYLERMFELIDTLLHHPALEGRKVLGIGVGAPGPTLHSTGVVIYSASLNWENFPLKQKLSERYDLPIMVENDINLAAMGELWFGAGKGRKNFFVLASGGGIGSAMVIDGAVYRGAHEFAGEIANMLPGREFLYKKRGKLGSLETVMSGIGLSNQAREVLKGQLPEESLNAITIKEFFRAVRREEEWAMPIYQNALDYLALAVSSVISITDPEVVIFAGGIAAFADLLIEPVKERLGDLLPMGVNLVQSPLGLRGCVMGAIAKVMYHTAGYYVVHKIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XEY9</accession>
    <name>A0A0P6XEY9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4 5">30S ribosomal protein S12</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">rpsL</name>
        <name evidence="6" type="ORF">ADN00_06875</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">Interacts with and stabilizes bases of the 16S rRNA that are involved in tRNA selection in the A site and with the mRNA backbone. Located at the interface of the 30S and 50S subunits, it traverses the body of the 30S subunit contacting proteins on the other side and probably holding the rRNA structure together. The combined cluster of proteins S8, S12 and S17 appears to hold together the shoulder and platform of the 30S subunit.</text>
    </comment>
    <comment type="function">
        <text evidence="1 4 5">With S4 and S5 plays an important role in translational accuracy.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 5">Part of the 30S ribosomal subunit. Contacts proteins S8 and S17. May interact with IF1 in the 30S initiation complex.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the universal ribosomal protein uS12 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062245.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06875"/>
    <dbReference type="EnsemblBacteria" id="KPL78206">
        <property type="protein sequence ID" value="KPL78206"/>
        <property type="gene ID" value="ADN00_06875"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3191"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015935">
        <property type="term" value="C:small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03368">
        <property type="entry name" value="Ribosomal_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00403_B">
        <property type="entry name" value="Ribosomal_S12_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006032">
        <property type="entry name" value="Ribosomal_S12/S23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005679">
        <property type="entry name" value="Ribosomal_S12_bac"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11652">
        <property type="entry name" value="PTHR11652"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00164">
        <property type="entry name" value="Ribosom_S12_S23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01034">
        <property type="entry name" value="RIBOSOMALS12"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00981">
        <property type="entry name" value="rpsL_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00055">
        <property type="entry name" value="RIBOSOMAL_S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4 6" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="4 5" id="KW-0699">rRNA-binding</keyword>
    <keyword evidence="4 5" id="KW-0820">tRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00015690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL78206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="139" mass="15577" checksum="99F70A73F4DD36D3" modified="2016-01-20" version="1">MPTINQLIRKGRETKKVKSKAPALQFTYNSMKQRRVRQAGGAPQKRGVCTVVRTMTPKKPNSALRKIARVRLSNTIEVTAYIPGEGHSLQEHSVVMVRGGRVKDLPGVRYHIVRGTLDTTGVNNRKQARSKYGTKRAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XF24</accession>
    <name>A0A0P6XF24_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_14375</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000034">
        <property type="protein sequence ID" value="KPL73771.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063747.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000034.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14375"/>
    <dbReference type="EnsemblBacteria" id="KPL73771">
        <property type="protein sequence ID" value="KPL73771"/>
        <property type="gene ID" value="ADN00_14375"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1394"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL73771.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="240" mass="26364" checksum="0F178A5265412E5F" modified="2016-01-20" version="1">MLTINQLEASYGGIRALRGVSLRVEQGEIVAVLGSNGAGKSTLLKAISAVVKPTAGEILLEGVPTPRVPYRVVEAGIVHVPEGRQIIPNLTVYENLMIGCFLRNDHQQIQKDLEMVYHYFPRLEERKKQYGGLLSGGEQQMLALGRGLMAKPKIMMLDEPSLGLAPIIVNQIFEILTTINREQGATILIVEQNAYKALSIAHRGYMMTTGLVEAEGNAQELLERENLEEIYLGQAGGNRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XFG6</accession>
    <name>A0A0P6XFG6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">8-amino-7-ketopelargonate synthase</fullName>
            <ecNumber evidence="7">2.3.1.47</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_03320</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Catalyzes the decarboxylative condensation of pimeloyl-[acyl-carrier protein] and L-alanine to produce 8-amino-7-oxononanoate (AON), [acyl-carrier protein], and carbon dioxide.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 7">
            <text>6-carboxyhexanoyl-[ACP] + H(+) + L-alanine = (8S)-8-amino-7-oxononanoate + CO2 + holo-[ACP]</text>
            <dbReference type="Rhea" id="RHEA:42288"/>
            <dbReference type="Rhea" id="RHEA-COMP:9685"/>
            <dbReference type="Rhea" id="RHEA-COMP:9955"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57972"/>
            <dbReference type="ChEBI" id="CHEBI:64479"/>
            <dbReference type="ChEBI" id="CHEBI:78846"/>
            <dbReference type="ChEBI" id="CHEBI:149468"/>
            <dbReference type="EC" id="2.3.1.47"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 6 7">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 7">Cofactor biosynthesis; biotin biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 7">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. BioF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.47" evidence="7"/>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78943.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061542.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03320"/>
    <dbReference type="EnsemblBacteria" id="KPL78943">
        <property type="protein sequence ID" value="KPL78943"/>
        <property type="gene ID" value="ADN00_03320"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.11"/>
    <dbReference type="UniPathway" id="UPA00078"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008710">
        <property type="term" value="F:8-amino-7-oxononanoate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016874">
        <property type="term" value="F:ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009102">
        <property type="term" value="P:biotin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001917">
        <property type="entry name" value="Aminotrans_II_pyridoxalP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010962">
        <property type="entry name" value="AONS_Archaea/Firmicutes"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004723">
        <property type="entry name" value="AONS_Archaea/Proteobacteria"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00858">
        <property type="entry name" value="bioF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01825">
        <property type="entry name" value="gly_Cac_T_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00599">
        <property type="entry name" value="AA_TRANSFER_CLASS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0093">Biotin biosynthesis</keyword>
    <keyword evidence="9" id="KW-0436">Ligase</keyword>
    <keyword evidence="6 7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="8">
        <location>
            <begin position="41"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="6">
        <location>
            <position position="241"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023383"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR604723-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL78943.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="394" mass="42843" checksum="8515051BE253990B" modified="2016-01-20" version="1">MTDQLQWIQTELDTLKDQGLYNHIRTLASPQGPWLVVDGKKALNFCSNNYLGLANHPRLVQAAKEIVDRYGVGPTAVRSIAGTMDIHLELERRLAQFKGVEAAVTFQSGFCANLAVIPALVSKEDVIFSDELNHASIIDGSRLSRARIERFAHANPADLERVIRANAGSYRRGLVITDGVFSMDGDLAPLDEIYAVSSAHDLMLMVDDAHGEGVVGKGGRGIVDHFNLHGKVDVEVGTLSKAFGVVGGVVAGKSVIVEWLRQRGRPFLFSSAVTPPDVAACLAAVDLLEESTDLVDKLWENSRYFKTEMKALGFDTGLSVTPITPIMLGEAPLAQQFSRELYNEGVFAMAIGFPTVPQGKARIRVMISASHSRDDLDYGLQAFAKVGRKLGVIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XFY8</accession>
    <name>A0A0P6XFY8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_06580</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000017">
        <property type="protein sequence ID" value="KPL78581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062183.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000017.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06580"/>
    <dbReference type="EnsemblBacteria" id="KPL78581">
        <property type="protein sequence ID" value="KPL78581"/>
        <property type="gene ID" value="ADN00_06580"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012495">
        <property type="entry name" value="TadE"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07811">
        <property type="entry name" value="TadE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="26"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="250" mass="28045" checksum="E0ABDC33496E8F8F" modified="2016-01-20" version="1">MQKFLQRLPSLHQTVLNRARSRGQSFLELALILPILLLMLLGLVEISFFIGRYLDILDLTREAARFASVRDPFMNAPIDTVSCSAGEPFNFYYHTACIFSPPTGSANCTDTKFCNGLNSFVALNPEIDDVVITVYTVSDWHVSSPVFPQPKGYWALSNIDSDTAHNDNWQRDCQGKVVRSTPYFTADRINDTLEPSSPKSKGLVAVEFYYCYHQALNLPVLTNFVPNPLRIHAYTLMPIPAAQPSPTPRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGE5</accession>
    <name>A0A0P6XGE5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">PGA_cap domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_19185</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CapA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064650.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_19185"/>
    <dbReference type="EnsemblBacteria" id="KPL70155">
        <property type="protein sequence ID" value="KPL70155"/>
        <property type="gene ID" value="ADN00_19185"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019079">
        <property type="entry name" value="Capsule_synth_CapA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09587">
        <property type="entry name" value="PGA_cap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00854">
        <property type="entry name" value="PGA_cap"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="SSF56300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133048" description="PGA_cap domain-containing protein" evidence="3">
        <location>
            <begin position="22"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="domain" description="PGA_cap" evidence="4">
        <location>
            <begin position="251"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="26"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="39"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005662"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00854"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL70155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="553" mass="60733" checksum="759B680779D4C231" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGG7</accession>
    <name>A0A0P6XGG7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Fe-S oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13815</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063610.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000032.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13815"/>
    <dbReference type="EnsemblBacteria" id="KPL74365">
        <property type="protein sequence ID" value="KPL74365"/>
        <property type="gene ID" value="ADN00_13815"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1340"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023862">
        <property type="entry name" value="CHP03960_rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045784">
        <property type="entry name" value="Radical_SAM_N2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19864">
        <property type="entry name" value="Radical_SAM_N2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03960">
        <property type="entry name" value="rSAM_fuse_unch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Radical SAM core" evidence="1">
        <location>
            <begin position="258"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="634" mass="71397" checksum="FE85F501700A982B" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGU9</accession>
    <name>A0A0P6XGU9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL74112">
        <property type="protein sequence ID" value="KPL74112"/>
        <property type="gene ID" value="ADN00_13990"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL74112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="104" mass="11058" checksum="CA12EEB040B3F0EC" modified="2016-01-20" version="1">MPGVLPCGRPANAPAAVRHHPPPRAGGLNCHPAAPAARPAPARDRRRKPPRRARPPAALRVARHAAARGQRAGNTTPDHPLRMRPGRRRARGPQTGSQLTGTAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGW2</accession>
    <name>A0A0P6XGW2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MFS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_14115</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000033">
        <property type="protein sequence ID" value="KPL74131.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063671.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000033.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14115"/>
    <dbReference type="EnsemblBacteria" id="KPL74131">
        <property type="protein sequence ID" value="KPL74131"/>
        <property type="gene ID" value="ADN00_14115"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="23"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="88"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="112"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="145"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="176"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="217"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="262"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="286"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="310"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="343"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="374"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="1"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL74131.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="409" mass="43989" checksum="842D83463AA0D18F" modified="2016-01-20" version="1">MIASFRTRIDRALGAQPHQIQNMLAYFAAFGGLGLLGSLVGPTLPTLAEQTGSRVGALGLIFFLRSLGFSIGTVTLGRLVDRVKINQLMGACVFADGLAVILIPSLHSNWLLGAAFMFAGLMESVIAVAANTGIVWMYNERANPVITGLHFCFGLGAFIAPLIVAQLINQAEGVKLSYWIVSAYLLLVGATLLLRAHSPLPSESHEEARAATTRSDYVLVAVTSMMLFFYVGAEISFSGWYFTFLTSLNVVVEQTAAYMNSAFWLAFTAGRLIAVLLSMRVKSQTILLVALLGCLTAMGMLILLPPLPAVLWLVPALTGFFMAPIFPVGFAWASESLRLTGRLTGIIFMGDSIGAMLLPWLAGMLLDTTGPQMLAPTVFLIMFLNLAAYLIMRRLVAHRQKQAGAASTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XH10</accession>
    <name>A0A0P6XH10_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HPt domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_04145</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061698.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04145"/>
    <dbReference type="EnsemblBacteria" id="KPL79075">
        <property type="protein sequence ID" value="KPL79075"/>
        <property type="gene ID" value="ADN00_04145"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.160">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036641">
        <property type="entry name" value="HPT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008207">
        <property type="entry name" value="Sig_transdc_His_kin_Hpt_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01627">
        <property type="entry name" value="Hpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00073">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47226">
        <property type="entry name" value="SSF47226"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50894">
        <property type="entry name" value="HPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HPt" evidence="2">
        <location>
            <begin position="17"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="modified residue" description="Phosphohistidine" evidence="1">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="116" mass="12131" checksum="EB71601A8DB28B68" modified="2016-01-20" version="1">MAQILNLDTVATLRDLGDDLVLDLIQTYVAESDRLVSEIAAAAAAGNAAQIGSLAHSLKGSSLNMGLEVIGEVGLRLEKCGKGGDVEGAKGLLPELEQKYAQTKQALAELEKQLNV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XH97</accession>
    <name>A0A0P6XH97_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Phytoene dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_13280</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1 4">Carotenoid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 4">Belongs to the carotenoid/retinoid oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063506.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000031.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13280"/>
    <dbReference type="EnsemblBacteria" id="KPL74813">
        <property type="protein sequence ID" value="KPL74813"/>
        <property type="gene ID" value="ADN00_13280"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1138"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00183"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016117">
        <property type="term" value="P:carotenoid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014105">
        <property type="entry name" value="Carotenoid/retinoid_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008150">
        <property type="entry name" value="Phytoene_DH_bac_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02734">
        <property type="entry name" value="crtI_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00982">
        <property type="entry name" value="PHYTOENE_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0125">Carotenoid biosynthesis</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amino_oxidase" evidence="5">
        <location>
            <begin position="14"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004829"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006046"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU362075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL74813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="495" mass="56326" checksum="4FE22AE0A334E8EB" modified="2016-01-20" version="1">MKKRKVIVIGSGFGGLATACRLAARGYEVEIFEKRDKLGGRGYVYEMNGFKFDGGPTVITAPFMFDDIFQAAGRNRADYVEFVPVNPFYRIFDHQGKEFNYNNDPEYILSEIDRWSPEDKKGYQEFIATTKPIFEKGFLELADQPFLHVTDMLKVAPDLIRLQSYKSVYQYVSQFVSNDFLRMVFSFHPLLVGGNPFETTSIYAMIHYLEREWGVFFAKGGTGAIVDAMEKLFKELGGKVHLKAEIQEILVEDKKVSGVRLADGSIHRADAIVSNADPAFTYTRLIQPHYRRVNTNARYQRMRYSMSLFVIYFGTNRRYTDSRLAHHNIILGPRYKGLLDDIFKKKTLADDFSLYLHMPTITDPSLAPEGHEAFYVLSPVPHLGSGVDWKTMARPYRDRIMQFLEDNYLPGLQSSIVAEHYIDPLHFQNTLNSYQGAAFSVEPILTQSAWFRPHNRSEDFSNLYLVGAGTHPGAGLPGVLSSAVIAENLISEDLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XHB1</accession>
    <name>A0A0P6XHB1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5 11 12">Xylose isomerase</fullName>
            <ecNumber evidence="4 11 12">5.3.1.5</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="primary">xylA</name>
        <name evidence="15" type="ORF">ADN00_13515</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="15 16" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="15 16">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10 11 12">
            <text>alpha-D-xylose = alpha-D-xylulofuranose</text>
            <dbReference type="Rhea" id="RHEA:22816"/>
            <dbReference type="ChEBI" id="CHEBI:28518"/>
            <dbReference type="ChEBI" id="CHEBI:188998"/>
            <dbReference type="EC" id="5.3.1.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="11">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="11">Binds 2 magnesium ions per subunit.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 11 13">Homotetramer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 11 13">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11 12">Belongs to the xylose isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.5" evidence="4 11 12"/>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74849.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063550.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000031.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13515"/>
    <dbReference type="EnsemblBacteria" id="KPL74849">
        <property type="protein sequence ID" value="KPL74849"/>
        <property type="gene ID" value="ADN00_13515"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1196"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009045">
        <property type="term" value="F:xylose isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042732">
        <property type="term" value="P:D-xylose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00455">
        <property type="entry name" value="Xylose_isom_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036237">
        <property type="entry name" value="Xyl_isomerase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013022">
        <property type="entry name" value="Xyl_isomerase-like_TIM-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013453">
        <property type="entry name" value="XylA_actinobac"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001998">
        <property type="entry name" value="Xylose_isomerase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01261">
        <property type="entry name" value="AP_endonuc_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00688">
        <property type="entry name" value="XYLOSISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51658">
        <property type="entry name" value="SSF51658"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02631">
        <property type="entry name" value="xylA_Arthro"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51415">
        <property type="entry name" value="XYLOSE_ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 11 12" id="KW-0119">Carbohydrate metabolism</keyword>
    <keyword evidence="6 11" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8 11 12" id="KW-0413">Isomerase</keyword>
    <keyword evidence="11" id="KW-0460">Magnesium</keyword>
    <keyword evidence="7 11 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 12" id="KW-0859">Xylose metabolism</keyword>
    <feature type="domain" description="AP_endonuc_2" evidence="14">
        <location>
            <begin position="43"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="55"/>
        </location>
    </feature>
    <feature type="active site" evidence="11">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="182"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="218"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="221"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="288"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005765"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018232"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00033659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00455"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU000609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU000610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KPL74849.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="388" mass="43333" checksum="A9601CF0ECF74153" modified="2016-01-20" version="1">MAAYQPTPEDKFTFGLWTVGNRGSDPFGGEVRGAKTPAEIVYMLAEVGAYGVNFHDNDLIPIDATPAEAEAIKRDFRKALDETGLVVPMATTNLFYDPIFKDGAFTSNDPKVRAYAIQKTMKAIDLGVEFGAGIYVFWGGREGTETDASKNPVDAIKRNRDAINFLCEYALEKKYDLKFALEAKPNEPRADIYNPTTGHMLAFIATLDHPEMVGVNPEVAHEHMAGLNFMHSVAQAWEAGKLFHIDLNDQYPGRYDQDLRFGSRDLKAAFFLVKFLEDIGYAGSRHFDAHAYRTEDYEGVKDFARGCMRTYLILKEKAKQWNEDKEIQSLVAEINADDGAMSSYLGKYSAEKAAALKAQPFDRAAIASRGLKYERLDQLTIDLLLGSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XHB7</accession>
    <name>A0A0P6XHB7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_13210</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74859.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063563.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000031.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13210"/>
    <dbReference type="EnsemblBacteria" id="KPL74859">
        <property type="protein sequence ID" value="KPL74859"/>
        <property type="gene ID" value="ADN00_13210"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1123"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="58"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="133"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="197"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="239"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="292"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="361"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="394"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="427"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="482"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="525"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="55"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="357"/>
            <end position="549"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL74859.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="560" mass="60649" checksum="C359AC2CACD5C160" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XHE6</accession>
    <name>A0A0P6XHE6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 7">Beta-galactosidase</fullName>
            <ecNumber evidence="3 7">3.2.1.23</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 7">Lactase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_03905</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>Hydrolysis of terminal non-reducing beta-D-galactose residues in beta-D-galactosides.</text>
            <dbReference type="EC" id="3.2.1.23"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the glycosyl hydrolase 2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.2.1.23" evidence="3 7"/>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03905"/>
    <dbReference type="EnsemblBacteria" id="KPL79230">
        <property type="protein sequence ID" value="KPL79230"/>
        <property type="gene ID" value="ADN00_03905"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.136"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009341">
        <property type="term" value="C:beta-galactosidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004565">
        <property type="term" value="F:beta-galactosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030246">
        <property type="term" value="F:carbohydrate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016052">
        <property type="term" value="P:carbohydrate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.98.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004199">
        <property type="entry name" value="B-gal_small/dom_5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036156">
        <property type="entry name" value="Beta-gal/glucu_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011013">
        <property type="entry name" value="Gal_mutarotase_sf_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014718">
        <property type="entry name" value="GH-type_carb-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006101">
        <property type="entry name" value="Glyco_hydro_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023232">
        <property type="entry name" value="Glyco_hydro_2_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006103">
        <property type="entry name" value="Glyco_hydro_2_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023230">
        <property type="entry name" value="Glyco_hydro_2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006102">
        <property type="entry name" value="Glyco_hydro_2_Ig-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006104">
        <property type="entry name" value="Glyco_hydro_2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032312">
        <property type="entry name" value="LacZ_4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02929">
        <property type="entry name" value="Bgal_small_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16353">
        <property type="entry name" value="DUF4981"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00703">
        <property type="entry name" value="Glyco_hydro_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02836">
        <property type="entry name" value="Glyco_hydro_2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02837">
        <property type="entry name" value="Glyco_hydro_2_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00132">
        <property type="entry name" value="GLHYDRLASE2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01038">
        <property type="entry name" value="Bgal_small_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49303">
        <property type="entry name" value="SSF49303"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="SSF49785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF74650">
        <property type="entry name" value="SSF74650"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00719">
        <property type="entry name" value="GLYCOSYL_HYDROL_F2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00608">
        <property type="entry name" value="GLYCOSYL_HYDROL_F2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0326">Glycosidase</keyword>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Bgal_small_N" evidence="8">
        <location>
            <begin position="740"/>
            <end position="1024"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001412"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007401"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012756"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032230"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU361154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01038"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL79230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="1026" mass="114898" checksum="A22DA414CD69EF9A" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XJF6</accession>
    <name>A0A0P6XJF6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01825</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000006">
        <property type="protein sequence ID" value="KPL80126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061256.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000006.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80126">
        <property type="protein sequence ID" value="KPL80126"/>
        <property type="gene ID" value="ADN00_01825"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="151"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="213" mass="23223" checksum="FEE4EEC3BCE2D80D" modified="2016-01-20" version="1">MNDPVQQMMKKTQRYWYVDGLAEIGAGALILLLGLLYLVVGWLPWQGVKAILLGLGMPVLLLGGMVGVRAWVNRAKQRLTYPRTGYVEYRRPKTARRWLVLLLSGVVSATTIALLINFMPLLGERFVMALTGLLVFAGMSYLAYQVNLWRFLLVGAAALAGGLLASLLNIPDPFNSALFFGVFGAAWLVSGGLTLRAYLASSTPAEEDADEEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XK20</accession>
    <name>A0A0P6XK20_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01325</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061161.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80519">
        <property type="protein sequence ID" value="KPL80519"/>
        <property type="gene ID" value="ADN00_01325"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="70"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="123" mass="13635" checksum="55813F3A1B9524BC" modified="2016-01-20" version="1">MKQVNWIEITRWSARLVSVLLLVLTLVIFFGEGLPAFAALTATEILMMLFFGLMAAGLVWAWWHPIAGGALTLLAFLFFAGVNLVSSGSLPGGWVFPLFPLNGALHLVYGFQLYCCRRFENQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKI8</accession>
    <name>A0A0P6XKI8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">E1_dh domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_11345</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>thiamine diphosphate</name>
            <dbReference type="ChEBI" id="CHEBI:58937"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063129.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11345"/>
    <dbReference type="EnsemblBacteria" id="KPL76550">
        <property type="protein sequence ID" value="KPL76550"/>
        <property type="gene ID" value="ADN00_11345"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.968"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016624">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors, disulfide as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001017">
        <property type="entry name" value="DH_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00676">
        <property type="entry name" value="E1_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="E1_dh" evidence="3">
        <location>
            <begin position="26"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL76550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="327" mass="35830" checksum="1DAC14D8FA4C9A5C" modified="2016-01-20" version="1">MKSDKNAPLKLSDYLTKEQGLELLKKMLLTRAFEENAEEQYALGKLHGTMHLSIGQEAIAAGVASATKKGDYLLNTHRGHGHFLQWGGDLNAMMAEFMGKANGICRGRGGSMHIADVSMNNLGAQGIVGGNMPISVGVGLSIQLRETDQVVVALFGDGAANEGAFHESLNLAALWKLPVIYLCENNRYAMSMAFDRAFTIEKISDRACAYNIPGHTFDGNDVLSVHAAVKEAARRARAGEGPTLLEAITYRWRGHSKSDRQAYRTRDEVKEWMEKDPIPRFASVLGVSAEELKALDQEARERIRAATEYADNSPEPDVNTIMEGVYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XLG8</accession>
    <name>A0A0P6XLG8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_00400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00400"/>
    <dbReference type="EnsemblBacteria" id="KPL81141">
        <property type="protein sequence ID" value="KPL81141"/>
        <property type="gene ID" value="ADN00_00400"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3473"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015661">
        <property type="term" value="F:L-lysine efflux transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005642">
        <property type="entry name" value="LysO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35804">
        <property type="entry name" value="PTHR35804"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03956">
        <property type="entry name" value="Lys_export"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="42"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="156"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL81141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="179" mass="18895" checksum="8853788CD0213A7A" modified="2016-01-20" version="1">MEWISAVGFPEQTQTLLIYALLFFIGVSVGSDEETLANLKTLNLLSLLVPFSILAGSLIGGAVGSVLINRIDVNEGMSIGAGLGYYSLSSVLIGQLRGEELGVIALMANIFREVSTILFAPLLVSLFGEMALIASGGATTSDTSLPVIQRYSGNRYTLIAVFNGIVLSLLVPLVVPLFL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XLJ4</accession>
    <name>A0A0P6XLJ4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">GTPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_11620</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76005.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063184.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11620"/>
    <dbReference type="EnsemblBacteria" id="KPL76005">
        <property type="protein sequence ID" value="KPL76005"/>
        <property type="gene ID" value="ADN00_11620"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3799"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76005.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="439" mass="48859" checksum="2B687AA255E29215" modified="2016-01-20" version="1">MTPIRTIIMGAAGRDFHNFNTFYRDNKDYEVVAFTATQIPNIEGRKYPAELAGSLYPKGIPIYPESDLVRLINEHKVDQVVFAYSDVPHEYVMHKASIVNAAGADFRLMGVGTTQIKSTKPVVAICAVRTGSGKSQTTRRVSKILIDMGYKVAAIRHPMPYGDLAKQAVQRFASYADLDKHECTIEEREEYEPHLDNGVIVYAGVDYEKILRQAEQEVDIVLWDGGNNDFSFYKTDLYIVVADPHRAGHELRYYPGETNLRLADVFVINKVDTAKPEDVIKVRESLFATKPDALIIEGASPLFVEDPAAIRGKRVLVIEDGPTLTHGEMAYGAGWVAARRFGAGEIVDPRPFAVGSIKATYQKYPNTGTILPAMGYGADMVKDLETTINNADVDLVISATPIDLTRVLKVNKPMQRVRYELQEIGQPSLEDVLKQKFGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XLZ1</accession>
    <name>A0A0P6XLZ1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_01160</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000003">
        <property type="protein sequence ID" value="KPL80854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01160"/>
    <dbReference type="EnsemblBacteria" id="KPL80854">
        <property type="protein sequence ID" value="KPL80854"/>
        <property type="gene ID" value="ADN00_01160"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1977"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015658">
        <property type="term" value="F:branched-chain amino acid transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06581">
        <property type="entry name" value="TM_PBP1_LivM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043428">
        <property type="entry name" value="LivM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30482">
        <property type="entry name" value="PTHR30482"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="81"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="104"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="133"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="162"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="241"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="290"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="320"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="361"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="393"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="397"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL80854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="412" mass="44776" checksum="49E5B58738412F9F" modified="2016-01-20" version="1">MRNYLPEMAPNYVNYYLFNQPILTGSLYNFALMVGGSLLGSLLARGVGRSAWRAKLNENVKASAQNVTKSSGFERLLNSKYSRYAMIALLAAVLILLPREWGPYWNYLMGTVGIYILLGVGLNIIVGLSGQLVLGYVAFFGIGAYTFGLLTSPQPHAIMMNFWLALIAGIALAAVTGILLGLPIMNLRGDYLAIVTLGFGEIIRILLKADLLEWFTAGPKGLRSLAQPTLFGKPFSSDVDYMYLIIIAVIISIFVANRIEKSRVGRAWLSIREDATVAQATGVNNFRYKLLALAIGAAFAGLAGALFASRNQFTGPEDHILMVSINVLCLVIVGGMGSIPGIILGSFVLKGLPEILREFEAYRMLAFGALLVVMMILRPEGLLPSSRPQLELFKPDSQAKTSEEVVEDAAHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XNH1</accession>
    <name>A0A0P6XNH1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF5668 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_14685</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000035">
        <property type="protein sequence ID" value="KPL73583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063784.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000035.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14685"/>
    <dbReference type="EnsemblBacteria" id="KPL73583">
        <property type="protein sequence ID" value="KPL73583"/>
        <property type="gene ID" value="ADN00_14685"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043726">
        <property type="entry name" value="DUF5668"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18917">
        <property type="entry name" value="DUF5668"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="33"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="domain" description="DUF5668" evidence="2">
        <location>
            <begin position="6"/>
            <end position="50"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF18917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL73583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="267" mass="29469" checksum="78EA6A757ED6C809" modified="2016-01-20" version="1">MRRNRLFWGSLVLLAGIILLMDTMGILPRGINGWQIIWPLALILAGFYFLLGPTLLKQDLTVDRVEIPLEGAQDVEIRMDYGAGYFHMSALEMPGTLLEGSFAGGLEHQMERRGPTAFLRMRPKITDVFDWPHWGGERGMEWNFAVSRDAVYHLIYNGGASESVFDLTDLQVRDLEIHTGASKTEVSLPSRVPLCRVSVEHGAAAVTLRVPADVAARVTVEGAAMGTNINTARFLQSGNVYQSPNYDSAEYRVEVSVKGGMGSIEVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XP60</accession>
    <name>A0A0P6XP60_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 11">Cytidine deaminase</fullName>
            <ecNumber evidence="6 11">3.5.4.5</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10 11">Cytidine aminohydrolase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">ADN00_10775</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 11">This enzyme scavenges exogenous and endogenous cytidine and 2'-deoxycytidine for UMP synthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 11">
            <text>2'-deoxycytidine + H(+) + H2O = 2'-deoxyuridine + NH4(+)</text>
            <dbReference type="Rhea" id="RHEA:13433"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15698"/>
            <dbReference type="ChEBI" id="CHEBI:16450"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.5"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 11">
            <text>cytidine + H(+) + H2O = NH4(+) + uridine</text>
            <dbReference type="Rhea" id="RHEA:16069"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16704"/>
            <dbReference type="ChEBI" id="CHEBI:17562"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="EC" id="3.5.4.5"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 11">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="5 11">Belongs to the cytidine and deoxycytidylate deaminase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.5" evidence="6 11"/>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063003.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10775"/>
    <dbReference type="EnsemblBacteria" id="KPL77038">
        <property type="protein sequence ID" value="KPL77038"/>
        <property type="gene ID" value="ADN00_10775"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2633"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004126">
        <property type="term" value="F:cytidine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047844">
        <property type="term" value="F:deoxycytidine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="RHEA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016192">
        <property type="entry name" value="APOBEC/CMP_deaminase_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002125">
        <property type="entry name" value="CMP_dCMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006262">
        <property type="entry name" value="Cyt_deam_tetra"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016193">
        <property type="entry name" value="Cytidine_deaminase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00383">
        <property type="entry name" value="dCMP_cyt_deam_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53927">
        <property type="entry name" value="SSF53927"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01354">
        <property type="entry name" value="cyt_deam_tetra"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00903">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51747">
        <property type="entry name" value="CYT_DCMP_DEAMINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 11" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 11" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="CMP/dCMP-type deaminase" evidence="12">
        <location>
            <begin position="6"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000393"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00000631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00003949"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00006576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00012783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00018266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU364006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51747"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KPL77038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="136" mass="14690" checksum="FAE1FA5E770D1424" modified="2016-01-20" version="1">MTLTAEMRDRLIQMAIEARKWAYVPYSHYPVGAALLTASGKVYDGVNIENAAYPTTICAERVAVFKAVSEGERQFEAIAVVTDNGGSPCGSCRQVLAEFGLDTLVYIADKDGQVRMETTVGGLLPGAFTPKDLPRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XP65</accession>
    <name>A0A0P6XP65_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Putative [LysW]-lysine hydrolase</fullName>
            <ecNumber evidence="1">3.5.1.130</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">lysK</name>
        <name evidence="2" type="ORF">ADN00_06675</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[amino-group carrier protein]-C-terminal-gamma-(L-lysyl)-L-glutamate + H2O = [amino-group carrier protein]-C-terminal-L-glutamate + L-lysine</text>
            <dbReference type="Rhea" id="RHEA:48684"/>
            <dbReference type="Rhea" id="RHEA-COMP:9693"/>
            <dbReference type="Rhea" id="RHEA-COMP:9715"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:32551"/>
            <dbReference type="ChEBI" id="CHEBI:78525"/>
            <dbReference type="ChEBI" id="CHEBI:78526"/>
            <dbReference type="EC" id="3.5.1.130"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <cofactor evidence="1">
            <name>Co(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:48828"/>
        </cofactor>
        <text evidence="1">Binds 2 Zn(2+) or Co(2+) ions per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; L-lysine biosynthesis via AAA pathway; L-lysine from L-alpha-aminoadipate (Thermus route): step 5/5.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M20A family. LysK subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.1.130" evidence="1"/>
    <dbReference type="EMBL" id="LGCL01000018">
        <property type="protein sequence ID" value="KPL78406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06675"/>
    <dbReference type="EnsemblBacteria" id="KPL78406">
        <property type="protein sequence ID" value="KPL78406"/>
        <property type="gene ID" value="ADN00_06675"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2245"/>
    <dbReference type="UniPathway" id="UPA00033">
        <property type="reaction ID" value="UER00039"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050897">
        <property type="term" value="F:cobalt ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016811">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds, in linear amides"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019878">
        <property type="term" value="P:lysine biosynthetic process via aminoadipic acid"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01120">
        <property type="entry name" value="LysK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010175">
        <property type="entry name" value="LysK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002933">
        <property type="entry name" value="Peptidase_M20"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01546">
        <property type="entry name" value="Peptidase_M20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01902">
        <property type="entry name" value="dapE-lys-deAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="1" id="KW-0170">Cobalt</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0457">Lysine biosynthesis</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="active site" evidence="1">
        <location>
            <position position="66"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="119"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="88"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="120"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="142"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="321"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01120"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="348" mass="37499" checksum="49BA8A52E1DD3A7D" modified="2016-01-20" version="1">MKRMSQTLTGLVAAYSPSGAEGAAVRFLVERMRALGYDKAFVDPAGNAVGVLGRGPRQIVLLGHIDTVPGEIALRVDGDDFYGRGSVDAKGPLAAFTDAAAAAGARAGWQVVVIGAVGEEADSPGARYVKDVYRPEMAVIGEPSRWDRVTLGYKGSVWLELTWQQAVGHSAGNTRPVCERAVAGWQQLVDWANIFNEERQGAFEQLLISLRGMNSGDDGFMDWAKLKVNARLPVDMSPQEFVTQTRARLPEAQVMEMGYAIAAHRAERNTPLVRALLDGIRNEGGKPGFVLKTGTADMNVVAPLWQCPIAAYGPGDSNLDHAPNEHISLSEYAAAVRVLTRVLARIMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XTL0</accession>
    <name>A0A0P6XTL0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MOSC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_02055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000008">
        <property type="protein sequence ID" value="KPL79924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061302.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000008.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02055"/>
    <dbReference type="EnsemblBacteria" id="KPL79924">
        <property type="protein sequence ID" value="KPL79924"/>
        <property type="gene ID" value="ADN00_02055"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030151">
        <property type="term" value="F:molybdenum ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005302">
        <property type="entry name" value="MoCF_Sase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011037">
        <property type="entry name" value="Pyrv_Knase-like_insert_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03473">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50800">
        <property type="entry name" value="SSF50800"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51340">
        <property type="entry name" value="MOSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MOSC" evidence="1">
        <location>
            <begin position="17"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51340"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="155" mass="16943" checksum="F476DBC978FBE50D" modified="2016-01-20" version="1">MTAWIFSITLSNEGMPKLPVQSGEVTAAGLAGDRQRNLKYHGGEARALCLFSLERLTALQQEGHPLYPGSTGENVLIAGLDWNQVIPGARLKLGGQVEIEVTNYTEPCHTIRDNFIGQDLKRMLQEANPGWSRVYARVLTPGAIRVSDEVTLQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XU75</accession>
    <name>A0A0P6XU75_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_05380</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78684.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061948.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05380"/>
    <dbReference type="EnsemblBacteria" id="KPL78684">
        <property type="protein sequence ID" value="KPL78684"/>
        <property type="gene ID" value="ADN00_05380"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007630">
        <property type="entry name" value="RNA_pol_sigma70_r4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04545">
        <property type="entry name" value="Sigma70_r4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="6">
        <location>
            <begin position="24"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4" evidence="7">
        <location>
            <begin position="126"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL78684.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="183" mass="20809" checksum="1788D84D203AEF20" modified="2016-01-20" version="1">MNRSDNAVLQRARKMDADALAWIYDEFSPAIFAYAYRLTGDSYLAEECVSETFSRLLQSLRAGGGPQDHLKAYLYRIAHNWVTDQYRRAAPAAESWEDENESVSKDVPTTQARIEEREQKMEIRNALRVLTADQRLVITLRFLEDQTIEQIALALQKPAGAVKALQHRALQTLKKALSKPDKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XV10</accession>
    <name>A0A0P6XV10_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_09175</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062696.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09175"/>
    <dbReference type="EnsemblBacteria" id="KPL77295">
        <property type="protein sequence ID" value="KPL77295"/>
        <property type="gene ID" value="ADN00_09175"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4069"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="86"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="4"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="40"/>
            <end position="47"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL77295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="240" mass="26339" checksum="26A582CB56FFB296" modified="2016-01-20" version="1">MEVAKIENISRIYKIGQVETQALRNVNLTIESGEFTALVGPSGSGKTTLLQLIGCLDQPTSGKLTINGKDVSQLDRNQRADMRRGTIGFIFQFFALIPTLTAYENIEMPLLLNGKSPAERQQRVNQLLKAIDLEDHSHHRPDQLSGGQQQRVAIARALVTQPALILADEPTANLDTPNGKLVMETMVRLNQETGVTFVFATHDPRVIQYARRIVTLRDGMIVSDEAGEGQLVESAAPVLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XV35</accession>
    <name>A0A0P6XV35_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_09360</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the membrane fusion protein (MFP) (TC 8.A.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77323.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062728.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09360"/>
    <dbReference type="EnsemblBacteria" id="KPL77323">
        <property type="protein sequence ID" value="KPL77323"/>
        <property type="gene ID" value="ADN00_09360"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4106"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032317">
        <property type="entry name" value="HlyD_D23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039562">
        <property type="entry name" value="MFP_biotin_lipoyl_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006143">
        <property type="entry name" value="RND_pump_MFP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13533">
        <property type="entry name" value="Biotin_lipoyl_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16576">
        <property type="entry name" value="HlyD_D23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01730">
        <property type="entry name" value="RND_mfp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="20"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="domain" description="Biotin_lipoyl_2" evidence="4">
        <location>
            <begin position="77"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="HlyD_D23" evidence="5">
        <location>
            <begin position="242"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="109"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="243"/>
            <end position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF13533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF16576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL77323.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="483" mass="51802" checksum="EDC3A656743321B0" modified="2016-01-20" version="1">MTESKSKQPTNPGRRRRQIAMITVALTALLVAAAWLWQRQQAQNASAPIYQTSVVRRGDLVLTVTGTGNLAATSIQELAFPVSGKVAEVNVQVGDEVKAGQVLAVLDNLDELALEVETQQLAVKAAEKELETLLASADRSLAEAQIALSDAQASYEEAKANLHQKGDGRCSKDLTESYFYAYLRAKIEADKWENYYNDGVGYGTNFVLEHLQPLLEEKNQAYQNWKYCEAYTEQEILESEANLATAEAAVHLAQAQLEEQSANGGVSAASLELAQAELESAQAALAEAEENLTGATLTAPFDGVVTEVAANAGETVDSDTFIQIADLYHPAVEIQIDEVDLQNIAEGCTAEVMFDAIPDRIFSGEITNIFPTLVSVFDFDTLSGMVSLEDQITASGKILPSGLSSLVDLKCRSASNALYIPLEALHYSENGDGFVYVLNAQGAAEMRKVSTGLETITAVEVTSGLSEGEIVITSGVSPESSQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XWJ7</accession>
    <name>A0A0P6XWJ7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_08030</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77825.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062471.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08030"/>
    <dbReference type="EnsemblBacteria" id="KPL77825">
        <property type="protein sequence ID" value="KPL77825"/>
        <property type="gene ID" value="ADN00_08030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL77825.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="240" mass="27093" checksum="1ABDA01C1EC0090E" modified="2016-01-20" version="1">MQVYFIRHAQSSNNALWVNTGSSLGRSEDPELTDLGWRQARIVADFVNSTPGGAVQDPADIQNLNGLEITHLYSSLMTRALSTAHCIAEEIGLPVRGWVDLHECGGIYLDDEISGERVGLAGKTAKALAERFPLLQLPDGLPESGWWSRPYENQELWYGRARRVYEQLMRLHGDGDDRVALVSHGCFFRYFLCAVFGLEDSDGLWFEVNNAAISRLEITPDSRRIFYLNRVDFLPREMIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XY28</accession>
    <name>A0A0P6XY28_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">5-nitroimidazole antibiotic resistance protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_00115</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL80997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060927.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00115"/>
    <dbReference type="EnsemblBacteria" id="KPL80997">
        <property type="protein sequence ID" value="KPL80997"/>
        <property type="gene ID" value="ADN00_00115"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3419"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024747">
        <property type="entry name" value="Pyridox_Oxase-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12900">
        <property type="entry name" value="Pyridox_ox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL80997.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="163" mass="18666" checksum="E390AC445EEC243F" modified="2016-01-20" version="1">MFREMRRKKQQLPNEISERILETGLVGVLGVTGDEDYPYTVPLNYVYENGKIYFHCAKTGHKLDGIQRNNKVSFCVIERDEIAAEKFTSFFRSVIAFGKAKIVEDGVVKKHALMLLVRKYSPGLEVEGEKVIQKGWNNLNVVEIEMDHVTGKEAIELVNNKEF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y015</accession>
    <name>A0A0P6Y015_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FeoA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_05265</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061926.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05265"/>
    <dbReference type="EnsemblBacteria" id="KPL78667">
        <property type="protein sequence ID" value="KPL78667"/>
        <property type="gene ID" value="ADN00_05265"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.90">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007167">
        <property type="entry name" value="Fe-transptr_FeoA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038157">
        <property type="entry name" value="FeoA_core_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008988">
        <property type="entry name" value="Transcriptional_repressor_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04023">
        <property type="entry name" value="FeoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00899">
        <property type="entry name" value="FeoA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50037">
        <property type="entry name" value="SSF50037"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FeoA" evidence="2">
        <location>
            <begin position="7"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="79" mass="8444" checksum="78077D16E8391A0B" modified="2016-01-20" version="1">MIPVAVMNLSMAASGEKVRMVSIQGGHELRKRLADLGLNIGEEVYVIQVACDGPMLLGVKDSRLAIGRGMAHKIMVEPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y068</accession>
    <name>A0A0P6Y068_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_05615</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FGGY kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061991.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05615"/>
    <dbReference type="EnsemblBacteria" id="KPL78721">
        <property type="protein sequence ID" value="KPL78721"/>
        <property type="gene ID" value="ADN00_05615"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1600"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000577">
        <property type="entry name" value="Carb_kinase_FGGY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="Carb_kinase_FGGY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018483">
        <property type="entry name" value="Carb_kinase_FGGY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018484">
        <property type="entry name" value="Carb_kinase_FGGY_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02782">
        <property type="entry name" value="FGGY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00370">
        <property type="entry name" value="FGGY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000538">
        <property type="entry name" value="GlpK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00933">
        <property type="entry name" value="FGGY_KINASES_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00445">
        <property type="entry name" value="FGGY_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FGGY_N" evidence="2">
        <location>
            <begin position="4"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="domain" description="FGGY_C" evidence="3">
        <location>
            <begin position="260"/>
            <end position="448"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL78721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="497" mass="55116" checksum="0AF5C2EE109E5815" modified="2016-01-20" version="1">MNPIILVVDQSTSATKAMLFTPQGELIDKESMDHEQIYPQPGWVEHNAEEIYQNLIQVVRRLLERHPERWSDLAGFSLTNQRETVVVFDRATGKPLHNAIVWLCRRGEPLCKQFVQEGKDAYVSERTGLKIDTYFPASKLRWILDNHADIQQKLQSGEALFGTIDTYVLYRLTNGQVYATDHTNASRTLLYDLHTLAWNFQLFELFGIQAAVAPEIRESRDRFGETTFEGLLEKPLPISGVMGDSQAALFAQRCFAPGEAKATFGTGSSLLLNIGHRPQLGKQGLVTAVAWVMDGQPTYAFEGITNFTGATIAWLRDKLELIRSTEETEALALSVPDTGGVYLVPAFVGLSAPYWRPDARAAIVGMSPSTGKAEVVRAALDSIAYIINDALELMSSEAGIHLQYIYADGGAVRNRYLMQFVADLSGMTVRVSQLQELSAFGAVLAGGLGLGLYASLEELKNLPIHYTEYMPQMDAAQVKKLQDGWKTAVQQVLYQSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y078</accession>
    <name>A0A0P6Y078_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_05675</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05675"/>
    <dbReference type="EnsemblBacteria" id="KPL78731">
        <property type="protein sequence ID" value="KPL78731"/>
        <property type="gene ID" value="ADN00_05675"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1612"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008658">
        <property type="term" value="F:penicillin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009002">
        <property type="term" value="F:serine-type D-Ala-D-Ala carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.710.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012338">
        <property type="entry name" value="Beta-lactam/transpept-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005311">
        <property type="entry name" value="PBP_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036138">
        <property type="entry name" value="PBP_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001460">
        <property type="entry name" value="PCN-bd_Tpept"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017790">
        <property type="entry name" value="Penicillin-binding_protein_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03717">
        <property type="entry name" value="PBP_dimer"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00905">
        <property type="entry name" value="Transpeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56519">
        <property type="entry name" value="SSF56519"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56601">
        <property type="entry name" value="SSF56601"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03423">
        <property type="entry name" value="pbp2_mrdA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PBP_dimer" evidence="3">
        <location>
            <begin position="45"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="domain" description="Transpeptidase" evidence="2">
        <location>
            <begin position="286"/>
            <end position="659"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00905"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL78731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="671" mass="73656" checksum="F2CD9812413F3C30" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y0Z6</accession>
    <name>A0A0P6Y0Z6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Translation initiation factor IF-3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="primary">infC</name>
        <name evidence="9" type="ORF">ADN00_13180</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">IF-3 binds to the 30S ribosomal subunit and shifts the equilibrum between 70S ribosomes and their 50S and 30S subunits in favor of the free subunits, thus enhancing the availability of 30S subunits on which protein synthesis initiation begins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4 5">Monomer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4 5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 4 5">Belongs to the IF-3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000030">
        <property type="protein sequence ID" value="KPL75184.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13180"/>
    <dbReference type="EnsemblBacteria" id="KPL75184">
        <property type="protein sequence ID" value="KPL75184"/>
        <property type="gene ID" value="ADN00_13180"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2887"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00080">
        <property type="entry name" value="IF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036788">
        <property type="entry name" value="T_IF-3_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036787">
        <property type="entry name" value="T_IF-3_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019813">
        <property type="entry name" value="Translation_initiation_fac3_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001288">
        <property type="entry name" value="Translation_initiation_fac_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019815">
        <property type="entry name" value="Translation_initiation_fac_3_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019814">
        <property type="entry name" value="Translation_initiation_fac_3_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10938">
        <property type="entry name" value="PTHR10938"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00707">
        <property type="entry name" value="IF3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05198">
        <property type="entry name" value="IF3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54364">
        <property type="entry name" value="SSF54364"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55200">
        <property type="entry name" value="SSF55200"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00168">
        <property type="entry name" value="infC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00938">
        <property type="entry name" value="IF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 4 5" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3 4 5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="IF3_N" evidence="8">
        <location>
            <begin position="8"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="IF3_C" evidence="7">
        <location>
            <begin position="84"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="163"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="173"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF05198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL75184.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="187" mass="21591" checksum="5C4D356AA269A03E" modified="2016-01-20" version="1">MSASEYRVNETIRVPKVRLIGADGDNLGVVDTREALKIAREAELDLVEVAPNSDPPVCRVMDFGKFLYERTKREREARKQQVKVEIKEIRLRPKTNEHHRSFKTRDARRWLEDGMKVKVTVRFRGREITYPELALEDLQEIADELADIAVVEQRPNMEGRVMTMLLSPNKEGKKKGASTKEETKEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y265</accession>
    <name>A0A0P6Y265_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase</fullName>
            <ecNumber evidence="2">2.7.6.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_03840</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cofactor biosynthesis; tetrahydrofolate biosynthesis; 2-amino-4-hydroxy-6-hydroxymethyl-7,8-dihydropteridine diphosphate from 7,8-dihydroneopterin triphosphate: step 4/4.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.3" evidence="2"/>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79032.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061644.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03840"/>
    <dbReference type="EnsemblBacteria" id="KPL79032">
        <property type="protein sequence ID" value="KPL79032"/>
        <property type="gene ID" value="ADN00_03840"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.122"/>
    <dbReference type="UniPathway" id="UPA00077">
        <property type="reaction ID" value="UER00155"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003848">
        <property type="term" value="F:2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046656">
        <property type="term" value="P:folic acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046654">
        <property type="term" value="P:tetrahydrofolate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00483">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.560">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000550">
        <property type="entry name" value="Hppk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035907">
        <property type="entry name" value="Hppk_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01288">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55083">
        <property type="entry name" value="SSF55083"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01498">
        <property type="entry name" value="folK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00794">
        <property type="entry name" value="HPPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0289">Folate biosynthesis</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="HPPK" evidence="8">
        <location>
            <begin position="87"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013253"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022909"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS00794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL79032.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="162" mass="18468" checksum="83891D286E377A2A" modified="2016-01-20" version="1">MNHTIYLALGTNLGDRQQNLATALRLLEAQVQGVHSSPIYETAPWGYLEQDNFLNIVARGQTRLTPPQLFNLVKSIENEMGRVKIIKDGPRLIDIDILFYDNQLYNSPTLEIPHPRMRGRSFVLVPLADLAPDFIHPVYHLAIRQLAAETDPSTLWLYNPRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y341</accession>
    <name>A0A0P6Y341_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_11860</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063229.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76044">
        <property type="protein sequence ID" value="KPL76044"/>
        <property type="gene ID" value="ADN00_11860"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3848"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="180" mass="19119" checksum="2D0457257AB10CD4" modified="2016-01-20" version="1">MNTPSQAQQLAEEARAAFQAGRYGEAASLFERAHSLSVQAGDALTAAEMANNLSVARLQAGDAAGALAAVQGTDQVFEQAGDTVKQAMALGNQAAAQEALGQLETALSLYQQSADLLKPHKDQAETRAFVLKSISSLQVRTGRQLEALASMNAALDQQKKLSLREKLLQKLLGIPFKQIK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y6Q5</accession>
    <name>A0A0P6Y6Q5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">ADN00_00925</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-54 factor family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061070.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00925"/>
    <dbReference type="EnsemblBacteria" id="KPL81117">
        <property type="protein sequence ID" value="KPL81117"/>
        <property type="gene ID" value="ADN00_00925"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3583"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000428">
        <property type="term" value="C:DNA-directed RNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001216">
        <property type="term" value="F:DNA-binding transcription activator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016779">
        <property type="term" value="F:nucleotidyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000394">
        <property type="entry name" value="RNA_pol_sigma_54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007046">
        <property type="entry name" value="RNA_pol_sigma_54_core-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007634">
        <property type="entry name" value="RNA_pol_sigma_54_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038709">
        <property type="entry name" value="RpoN_core-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32248">
        <property type="entry name" value="PTHR32248"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00309">
        <property type="entry name" value="Sigma54_AID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04963">
        <property type="entry name" value="Sigma54_CBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04552">
        <property type="entry name" value="Sigma54_DBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000774">
        <property type="entry name" value="RpoN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00045">
        <property type="entry name" value="SIGMA54FCT"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00718">
        <property type="entry name" value="SIGMA54_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0240">DNA-directed RNA polymerase</keyword>
    <keyword evidence="4" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0731">Sigma factor</keyword>
    <keyword evidence="8" id="KW-0804">Transcription</keyword>
    <keyword evidence="5" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Sigma54_CBD" evidence="10">
        <location>
            <begin position="110"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma54_DBD" evidence="9">
        <location>
            <begin position="322"/>
            <end position="462"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF04552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF04963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL81117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="469" mass="52681" checksum="E26F1524EB5FD591" modified="2016-01-20" version="1">MFQLHTQSIRPLTTAHLAQTMTLLSLTVDELRQQIDSELAANPALELVEERRCPTCKRILPDSGACPVCSSPNNLGQDEPLVFISPRDDFFSKEKSSEDEADYGADSFSTVVEDLPTYVLRQIAPDLEVADRRVAAHLLTHLDDDGLLDSNSIPELARYYHIPISRILEIQKLIQHADPIGVGSCSPNEAMLVQLDVLQDVSDIPPLAYSLIADGMSLLSRHQYAELAKKYHSTAAAVQDAFQFISENLNPYPARTHWGDVRQPAADTAEVYHHPDIIIGHINEDTSMPLVVEIIMPISGTLQINPMFRKAIKQVDESKKEEWKSDIERASLLVKCLQQRNHTMQRLLLEVVQRQKEAILIGDRHMVSLTRVELARQLDVHESTISRAVAKKTVQLPNKKIVPLASFFDRSLNVRTVLCDLIARENRPLSDAELVKMLAKEGFQVARRTVAKYRAMEGILPALLRHNPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YA16</accession>
    <name>A0A0P6YA16_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">PTS sugar transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">ADN00_05220</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell inner membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061918.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05220"/>
    <dbReference type="EnsemblBacteria" id="KPL78659">
        <property type="protein sequence ID" value="KPL78659"/>
        <property type="gene ID" value="ADN00_05220"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1518"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005351">
        <property type="term" value="F:carbohydrate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008982">
        <property type="term" value="F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003352">
        <property type="entry name" value="PTS_EIIC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013014">
        <property type="entry name" value="PTS_EIIC_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006327">
        <property type="entry name" value="PTS_IIC_fruc"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02378">
        <property type="entry name" value="PTS_EIIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01427">
        <property type="entry name" value="PTS_IIC_fructo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51104">
        <property type="entry name" value="PTS_EIIC_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
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    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 12" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="7 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="51"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="84"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="123"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="168"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="208"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="243"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="276"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="309"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="domain" description="PTS EIIC type-2" evidence="11">
        <location>
            <begin position="8"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004429"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022683"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51104"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KPL78659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="345" mass="35603" checksum="0D3AB227D3B87A05" modified="2016-01-20" version="1">MKRFLHDVQTHLLTGVSYMIPFVVPGGILIAIGFLLGGIKVYETPGFAAELFFLGKDAFGLMVAALAGYIAYSVADRPGIAPGFVGGIVATRIGAGFLGGMIAGLIAGYLVEAIKQIKVPQMIRSLMPVLIIPLLASTIVGLLMVYFIGPPVKWLNETMSVILNNLGTGSAIALGLLIGAMMAFDMGGPVNKAAYFFALGVAETANNWVPMGAVFVGGMVPPLVIAVAMLIANNKFTEEEKAGIPGCFVGAASLITEFAIPYAAGDPVRVMPSIMVGSAVGGAISMALGVSMMAPHGGLFVFALSNKPLLYVLSIIVGGIVGGLMLAAIKPKLEAEKVELDGQSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YA78</accession>
    <name>A0A0P6YA78_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_05680</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78732.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78732">
        <property type="protein sequence ID" value="KPL78732"/>
        <property type="gene ID" value="ADN00_05680"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78732.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="124" mass="13767" checksum="D2A3806FD2682C76" modified="2016-01-20" version="1">MLAGFGDQRLGNIDLALHGLGEILPLRHIDDTAIRSVNSFAIGRVDGQVLVITPLLKILIQRISNLFNLHRSHPGRSRHRNHIILALSDPLINILALRYGCLLKFSLDAFQQNGAALLVKQARH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YB35</accession>
    <name>A0A0P6YB35_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="11">Multidrug ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">ADN00_04560</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061773.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79134">
        <property type="protein sequence ID" value="KPL79134"/>
        <property type="gene ID" value="ADN00_04560"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.273"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011527">
        <property type="entry name" value="ABC1_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="PTHR24221"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00664">
        <property type="entry name" value="ABC_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90123">
        <property type="entry name" value="SSF90123"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50929">
        <property type="entry name" value="ABC_TM1F"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 6 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="50"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="92"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="298"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="10">
        <location>
            <begin position="53"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="369"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="402"/>
            <end position="409"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50929"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL79134.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="611" mass="66745" checksum="250117BE2F0EB5E2" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YD34</accession>
    <name>A0A0P6YD34_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_02080</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000008">
        <property type="protein sequence ID" value="KPL79929.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79929">
        <property type="protein sequence ID" value="KPL79929"/>
        <property type="gene ID" value="ADN00_02080"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79929.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="82" mass="8901" checksum="C79700E4A58B8DBC" modified="2016-01-20" version="1">MGTGLLKQGELFFALCGRAAGKFSGQTAWIAKPMEMSKVVQTGVCSIVRHSRRKSAPQVLIISFLRQKRSGGARHKPDLVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YDH1</accession>
    <name>A0A0P6YDH1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01945</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000007">
        <property type="protein sequence ID" value="KPL80057.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061280.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000007.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80057">
        <property type="protein sequence ID" value="KPL80057"/>
        <property type="gene ID" value="ADN00_01945"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="97"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="164"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="194"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="309"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="337"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="386"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="418"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="442"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="475"/>
            <end position="496"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80057.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="616" mass="64331" checksum="9C9D3F1F8F3CB9E6" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMB8</accession>
    <name>A0A0N8GMB8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Thiamine diphosphokinase</fullName>
            <ecNumber evidence="1">2.7.6.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_13200</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.6.2" evidence="1"/>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13200"/>
    <dbReference type="EnsemblBacteria" id="KPL74858">
        <property type="protein sequence ID" value="KPL74858"/>
        <property type="gene ID" value="ADN00_13200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030975">
        <property type="term" value="F:thiamine binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004788">
        <property type="term" value="F:thiamine diphosphokinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009229">
        <property type="term" value="P:thiamine diphosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006772">
        <property type="term" value="P:thiamine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07995">
        <property type="entry name" value="TPK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006282">
        <property type="entry name" value="Thi_PPkinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007373">
        <property type="entry name" value="Thiamin_PyroPKinase_B1-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036371">
        <property type="entry name" value="TPK_B1-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007371">
        <property type="entry name" value="TPK_catalytic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036759">
        <property type="entry name" value="TPK_catalytic_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04265">
        <property type="entry name" value="TPK_B1_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04263">
        <property type="entry name" value="TPK_catalytic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00983">
        <property type="entry name" value="TPK_B1_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63862">
        <property type="entry name" value="SSF63862"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63999">
        <property type="entry name" value="SSF63999"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01378">
        <property type="entry name" value="thi_PPkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="TPK_B1_binding" evidence="6">
        <location>
            <begin position="136"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013245"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL74858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="212" mass="23004" checksum="5EEB206D02842CA1" modified="2016-01-20" version="1">MRDAGPLLAQIQPGDLFIVVDGGLRHLSALGLRPQVLIGDLDSVDADAEERAREAGCSVLRYPPHKDETDLELALAYALQEGCTTLCIAGGLGGRLDHTLGNLYLLTQPALEGCQVRLDDGVDEVFVVRQSVEITGKSRDRVSLLPVSEIVTGVRTEGLAYPLRDETLYRERTRGISNVMLAEQAKVWIESGLLWCIHSRLGSPQDSSGGEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMH5</accession>
    <name>A0A0N8GMH5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">N6_N4_Mtase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_13060</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the N(4)/N(6)-methyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000028">
        <property type="protein sequence ID" value="KPL75314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063468.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000028.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13060"/>
    <dbReference type="REBASE" id="132875">
        <property type="entry name" value="M.OapP3M1ORF13060P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL75314">
        <property type="protein sequence ID" value="KPL75314"/>
        <property type="gene ID" value="ADN00_13060"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2736"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008170">
        <property type="term" value="F:N-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006306">
        <property type="term" value="P:DNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002941">
        <property type="entry name" value="DNA_methylase_N4/N6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01555">
        <property type="entry name" value="N6_N4_Mtase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="N6_N4_Mtase" evidence="4">
        <location>
            <begin position="75"/>
            <end position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL75314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="847" mass="96738" checksum="49E9ADB9803CA9F2" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMT3</accession>
    <name>A0A0N8GMT3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 5">50S ribosomal protein L4</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">rplD</name>
        <name evidence="7" type="ORF">ADN00_12595</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Forms part of the polypeptide exit tunnel.</text>
    </comment>
    <comment type="function">
        <text evidence="5">One of the primary rRNA binding proteins, this protein initially binds near the 5'-end of the 23S rRNA. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uL4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76178.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063379.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12595"/>
    <dbReference type="EnsemblBacteria" id="KPL76178">
        <property type="protein sequence ID" value="KPL76178"/>
        <property type="gene ID" value="ADN00_12595"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4000"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1370.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01328_B">
        <property type="entry name" value="Ribosomal_L4_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002136">
        <property type="entry name" value="Ribosomal_L4/L1e"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023574">
        <property type="entry name" value="Ribosomal_L4_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013005">
        <property type="entry name" value="Ribosomal_uL4/L1e"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10746">
        <property type="entry name" value="PTHR10746"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00573">
        <property type="entry name" value="Ribosomal_L4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52166">
        <property type="entry name" value="SSF52166"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03953">
        <property type="entry name" value="rplD_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 5 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="5" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="5" id="KW-0699">rRNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="51"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010528"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019302"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01328"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL76178.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="208" mass="22898" checksum="D4B0DA791387C15B" modified="2016-01-20" version="1">MLVDVYNMEGKKVDSVELPGAIFEAPVYVDLMHQAFVRQMANARLGTHDTKVRGEVSGGGRKPWRQKGTGRARQGSIRAAQWKGGGRIHTPHPRKYTKAMPRKMRLAALRSALSVKAAEANVVMLDQLALPEPKTRLMAKALDTLVGDCSALILIPEKEAYEGVIRATNNLPDAKIMLSGYLNIRDLLKYEKLVMPVASLESISNHLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMX9</accession>
    <name>A0A0N8GMX9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">PTS galactitol transporter subunit IIB</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_11325</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76546.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063125.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11325"/>
    <dbReference type="EnsemblBacteria" id="KPL76546">
        <property type="protein sequence ID" value="KPL76546"/>
        <property type="gene ID" value="ADN00_11325"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.964"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008982">
        <property type="term" value="F:protein-N(PI)-phosphohistidine-sugar phosphotransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009401">
        <property type="term" value="P:phosphoenolpyruvate-dependent sugar phosphotransferase system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036095">
        <property type="entry name" value="PTS_EIIB-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013011">
        <property type="entry name" value="PTS_EIIB_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003501">
        <property type="entry name" value="PTS_EIIB_2/3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02302">
        <property type="entry name" value="PTS_IIB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52794">
        <property type="entry name" value="SSF52794"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51099">
        <property type="entry name" value="PTS_EIIB_TYPE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PTS EIIB type-2" evidence="2">
        <location>
            <begin position="5"/>
            <end position="95"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51099"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL76546.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="95" mass="9844" checksum="4C0006C7BF9B8B36" modified="2016-01-20" version="1">MAGKKRILVSCGTAIATSTVVAKAIEEALKSRGIAVDIRQCKAAEVPSLADGMDLIVTTTPVPNNLGIPVIQTLAFLTGIGKEAVIEDIVKALKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GN45</accession>
    <name>A0A0N8GN45_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Flavin_Reduct domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10470</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10470"/>
    <dbReference type="EnsemblBacteria" id="KPL77074">
        <property type="protein sequence ID" value="KPL77074"/>
        <property type="gene ID" value="ADN00_10470"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016646">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-NH group of donors, NAD or NADP as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002563">
        <property type="entry name" value="Flavin_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01613">
        <property type="entry name" value="Flavin_Reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavin_Reduct" evidence="1">
        <location>
            <begin position="16"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="173" mass="19066" checksum="1D361F629AC29A72" modified="2016-01-20" version="1">MPLDSLRVAPHALFDQQWLLLTAGDFAAGDFNSMTISWGALGTIWNRPLVMVAVRPTRYTYVFMERYPNFTLSAFAPVYRPALNLLGSRSGREMDKIAASGLTPAAVPGCSAPAFMEAELVLVCEKMYWQDVNPAQMCDPSFYLDSAQPDPHRVYFGEARAAYGLARFAGEAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNB8</accession>
    <name>A0A0N8GNB8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_08675</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000022">
        <property type="protein sequence ID" value="KPL77658.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062600.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000022.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77658">
        <property type="protein sequence ID" value="KPL77658"/>
        <property type="gene ID" value="ADN00_08675"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026898">
        <property type="entry name" value="PrsW"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13367">
        <property type="entry name" value="PrsW-protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="54"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="93"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="117"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="161"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="267"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="293"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="331"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="374"/>
            <end position="392"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="429" mass="45280" checksum="6DE8F0FF185C30CC" modified="2016-01-20" version="1">MQPTQKTHWPSVLQVALSGLMLILLLPSAAGLLVVSAMGGLAQGASGQEVISLVHLAWMAALGAALQAPALVFGLARLLNWPLAQKERNPRRWLLLALAAWPLALAAGYGVNQLPGLSLVLLPPLQIAVVALPLAAFVLLGQMGLPRLTRQQNWGTVSFSLAITPLVTIAAEGVVGGLLLVALVVWLTSNPEAMEQIYRAGQRLSNAQMDPEALSRIIAPFLKNPQIIIGALTFTAGLVPLLEELFKPLALWLLAGKRLTPAQGFSGGLLAGAMFALFESLGMLASAAGAQDWLTLVIGRTGTGLLHVVTTGLVGWGLASAWQAGRYLRLGLAYLCAVLLHGIWNLFGILMGLLPVGGAVDLPQNLQGLTRLSQVAPLALGVLFLVLFSILLRGASLLRQEGNPIRIDISNHERVDPTQAKGVSTQGRE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNE7</accession>
    <name>A0A0N8GNE7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_08435</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062545.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08435"/>
    <dbReference type="EnsemblBacteria" id="KPL77890">
        <property type="protein sequence ID" value="KPL77890"/>
        <property type="gene ID" value="ADN00_08435"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.689"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="27"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="87"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="125"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="160"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="258"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="88"/>
            <end position="280"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL77890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="295" mass="32816" checksum="4BF549A069620BD8" modified="2016-01-20" version="1">MSTTTVQPKRKKSFFEGGREDSPFKRLLIHMALLAYCVITVYPLLRIFTVSIRPGNRLLSTDLAIIPADATLESYRIVLLEKPLLQWLWNSLAITAATAVIGVILAATSAYAFSRFKFPGRSLGLVFLLTTQMIPSAMLMVPIYILAIQMDLVGTYRGLVVAYSVTSIPFSIWILKGYYDTIPIDLEEAARIDGCTELEAFWRILLPLSAPALAIVFLFNFTQAWNDYLLARVMLGAQETLLTWPLGLQRLQGQFTTLWGQFSAGAILVTIPVMVLFLYTSKYLISGLTLGSVKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNR9</accession>
    <name>A0A0N8GNR9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glyco_trans_2-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_06565</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78866.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78866">
        <property type="protein sequence ID" value="KPL78866"/>
        <property type="gene ID" value="ADN00_06565"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1817"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001173">
        <property type="entry name" value="Glyco_trans_2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00535">
        <property type="entry name" value="Glycos_transf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_trans_2-like" evidence="1">
        <location>
            <begin position="3"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00535"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78866.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="503" mass="57469" checksum="0E1A45E400BC964D" modified="2016-01-20" version="1" fragment="single">MVSVLMPVSRKSVGTLRAIESVLAQSWRDFEFIIVDDGSVDGLFEVLREFQQRDARITLIRNHINSGLPAARVNQGVRVARGEYLAYMFEDDEWYPDALQIMLDTLQASAEPCAVYGIVDVDIQTPNGVERMHLGDWEFNYALLKNSNKIANCAVMHPRAFFDTCGLYDPHILVRRLSDYDLWLRMGRFFAFKPCRKVVGKSSGRNGRIGDDLGNGFLGFELRWIETNRVDALKPGTIDLYGINTTQITADPLEKNNLGEKVILPFLIQHPDLIPTQEKRPYLAASDSGHRLLVTKSDYSTSVDQHIRNFEEVLDKSLVSSFFLEDRKLQHGYPENFDTLVLYRTISGDSLSKMEVARRDHKTVVYLMDDNMLQFGRGYLAEEYSFLKPDTPAYRTMVKEIAGSDYVISYSTKISEDCAVFNPKVFQFRENIREYLIAPAAALQGGKATGRKLKFAVITGMARRKELQTLWAELQEFSRRHAEEVEFYLWGFDPAEFGELHCP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNW3</accession>
    <name>A0A0N8GNW3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 9">Chromosomal replication initiator protein DnaA</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">dnaA</name>
        <name evidence="14" type="ORF">ADN00_05095</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 9">Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'-TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 8">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8 10">Belongs to the DnaA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79218.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061873.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05095"/>
    <dbReference type="EnsemblBacteria" id="KPL79218">
        <property type="protein sequence ID" value="KPL79218"/>
        <property type="gene ID" value="ADN00_05095"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.389"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003688">
        <property type="term" value="F:DNA replication origin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006270">
        <property type="term" value="P:DNA replication initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006275">
        <property type="term" value="P:regulation of DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06571">
        <property type="entry name" value="Bac_DnaA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1750.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00377">
        <property type="entry name" value="DnaA_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001957">
        <property type="entry name" value="Chromosome_initiator_DnaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020591">
        <property type="entry name" value="Chromosome_initiator_DnaA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018312">
        <property type="entry name" value="Chromosome_initiator_DnaA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013317">
        <property type="entry name" value="DnaA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013159">
        <property type="entry name" value="DnaA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024633">
        <property type="entry name" value="DnaA_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038454">
        <property type="entry name" value="DnaA_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010921">
        <property type="entry name" value="Trp_repressor/repl_initiator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30050:SF2">
        <property type="entry name" value="PTHR30050:SF2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00308">
        <property type="entry name" value="Bac_DnaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08299">
        <property type="entry name" value="Bac_DnaA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11638">
        <property type="entry name" value="DnaA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00051">
        <property type="entry name" value="DNAA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00760">
        <property type="entry name" value="Bac_DnaA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48295">
        <property type="entry name" value="SSF48295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00362">
        <property type="entry name" value="DnaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01008">
        <property type="entry name" value="DNAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3 8" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 8 9" id="KW-0235">DNA replication</keyword>
    <keyword evidence="7 8 9" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 8 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="12">
        <location>
            <begin position="144"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="Bac_DnaA_C" evidence="13">
        <location>
            <begin position="352"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="93"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="152"/>
            <end position="159"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00377"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000577"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU004227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00760"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KPL79218.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="450" mass="50568" checksum="DD63B5EFB5220BE3" modified="2016-01-20" version="1">MNGQQAWQATVGQLQMEMSKAAFDTWVRSAEFVGHQNNTVTIGVQNAYARDWLESRLSSTVTRLISGMLSEPQQVEFIVYQKDYHDGPVELEEEAEAPASAQGESESSSSQTVNRYTFDNFVVGPSNRLAHAACMAVAENPAHAYNPMFLYGGVGLGKTHLLHAIGNSARAMGLTVLYVSSEDFTNDLVEAIRTRTTAAFRERYRRMDVLLIDDIQFIAGKESTQEEFFHTFNTLHGQEKQIVMSSDRPPKAMVTLEERLRSRFEWGLTVDIQPPDLETRVAILRSKAQRARRQVPPEILDLIARRIQSNIRELEGALTRVLAYADLSGQPLSNELVSSALADLIPQRSSIEPNQVLETVAAAFSMPLDRLLGRERSREVALPRQVAMYLLREEINISLPQIGETLGGRDHTTVMYACDKVADLIERDDRFRRQIIQIREKLYGRSPANG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNY8</accession>
    <name>A0A0N8GNY8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Core-binding (CB) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_02555</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000012">
        <property type="protein sequence ID" value="KPL79418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061393.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000012.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79418">
        <property type="protein sequence ID" value="KPL79418"/>
        <property type="gene ID" value="ADN00_02555"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044068">
        <property type="entry name" value="CB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010998">
        <property type="entry name" value="Integrase_recombinase_N"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51900">
        <property type="entry name" value="CB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Core-binding (CB)" evidence="3">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51900"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL79418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="133" mass="15715" checksum="F8D3563AF9FA28C0" modified="2016-01-20" version="1">MIERQNYLKTSKHLPFLQEVMQLNPASLDRYRFYLRHLLLWADDQNFRQVQAIRPTLPSYLASLPGKEGKGTLASASQKKIIDSSKRFFRWAKVTYPREMNNLPISWIDTLRRPRLPQISSEHVFVSLDEIQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GP68</accession>
    <name>A0A0N8GP68_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">DNA polymerase beta</fullName>
            <ecNumber evidence="4">2.7.7.7</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">ADN00_01950</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="21 22" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="21 22">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="17">Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="16">
            <text>a 2'-deoxyribonucleoside 5'-triphosphate + DNA(n) = diphosphate + DNA(n+1)</text>
            <dbReference type="Rhea" id="RHEA:22508"/>
            <dbReference type="Rhea" id="RHEA-COMP:17339"/>
            <dbReference type="Rhea" id="RHEA-COMP:17340"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:61560"/>
            <dbReference type="ChEBI" id="CHEBI:173112"/>
            <dbReference type="EC" id="2.7.7.7"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.7" evidence="4"/>
    <dbReference type="EMBL" id="LGCL01000007">
        <property type="protein sequence ID" value="KPL80058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061281.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000007.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01950"/>
    <dbReference type="EnsemblBacteria" id="KPL80058">
        <property type="protein sequence ID" value="KPL80058"/>
        <property type="gene ID" value="ADN00_01950"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2316"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00141">
        <property type="entry name" value="NT_POLXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.210.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002054">
        <property type="entry name" value="DNA-dir_DNA_pol_X"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010996">
        <property type="entry name" value="DNA_pol_b-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027421">
        <property type="entry name" value="DNA_pol_lamdba_lyase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037160">
        <property type="entry name" value="DNA_Pol_thumb_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002008">
        <property type="entry name" value="DNA_pol_X_beta-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003583">
        <property type="entry name" value="Hlx-hairpin-Hlx_DNA-bd_motif"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004013">
        <property type="entry name" value="PHP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003141">
        <property type="entry name" value="Pol/His_phosphatase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016195">
        <property type="entry name" value="Pol/histidinol_Pase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029398">
        <property type="entry name" value="PolB_thumb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022311">
        <property type="entry name" value="UCP005047_YshC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14791">
        <property type="entry name" value="DNA_pol_B_thumb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14716">
        <property type="entry name" value="HHH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02811">
        <property type="entry name" value="PHP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005047">
        <property type="entry name" value="UCP005047_YshC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00870">
        <property type="entry name" value="DNAPOLXBETA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00278">
        <property type="entry name" value="HhH1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00481">
        <property type="entry name" value="POLIIIAc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00483">
        <property type="entry name" value="POLXc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47802">
        <property type="entry name" value="SSF47802"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="SSF81301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89550">
        <property type="entry name" value="SSF89550"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="11" id="KW-0227">DNA damage</keyword>
    <keyword evidence="15" id="KW-0234">DNA repair</keyword>
    <keyword evidence="8" id="KW-0237">DNA synthesis</keyword>
    <keyword evidence="13" id="KW-0239">DNA-directed DNA polymerase</keyword>
    <keyword evidence="6" id="KW-0488">Methylation</keyword>
    <keyword evidence="10" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="14" id="KW-0915">Sodium</keyword>
    <keyword evidence="9" id="KW-0808">Transferase</keyword>
    <keyword evidence="12" id="KW-0832">Ubl conjugation</keyword>
    <feature type="domain" description="POLXc" evidence="20">
        <location>
            <begin position="1"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="HhH1" evidence="18">
        <location>
            <begin position="51"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="domain" description="HhH1" evidence="18">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="domain" description="HhH1" evidence="18">
        <location>
            <begin position="126"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="POLIIIAc" evidence="19">
        <location>
            <begin position="338"/>
            <end position="418"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00020020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022843"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00024632"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00025610"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="SMART" id="SM00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="19">
        <source>
            <dbReference type="SMART" id="SM00481"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="20">
        <source>
            <dbReference type="SMART" id="SM00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KPL80058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="574" mass="63982" checksum="69A7C8F08A163700" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GPJ8</accession>
    <name>A0A0N8GPJ8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Iron-sulfur cluster carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_00810</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the Mrp/NBP35 ATP-binding proteins family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the Mrp/NBP35 ATP-binding proteins family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">In the N-terminal section; belongs to the MIP18 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061048.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00810"/>
    <dbReference type="EnsemblBacteria" id="KPL81098">
        <property type="protein sequence ID" value="KPL81098"/>
        <property type="gene ID" value="ADN00_00810"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3560"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140663">
        <property type="term" value="F:ATP-dependent FeS chaperone activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016226">
        <property type="term" value="P:iron-sulfur cluster assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02040">
        <property type="entry name" value="Mrp_NBP35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034904">
        <property type="entry name" value="FSCA_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002744">
        <property type="entry name" value="MIP18-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019591">
        <property type="entry name" value="Mrp/NBP35_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000808">
        <property type="entry name" value="Mrp_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044304">
        <property type="entry name" value="NUBPL-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033756">
        <property type="entry name" value="YlxH/NBP35"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42961">
        <property type="entry name" value="PTHR42961"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01883">
        <property type="entry name" value="FeS_assembly_P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10609">
        <property type="entry name" value="ParA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117916">
        <property type="entry name" value="SSF117916"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01215">
        <property type="entry name" value="MRP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="5" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3 5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FeS_assembly_P" evidence="6">
        <location>
            <begin position="7"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="106"/>
            <end position="113"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL81098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="357" mass="37733" checksum="EC5A07C6168648D6" modified="2016-01-20" version="1">MSTSLQDRVLDALRTVQEPELHRDLVTLGMIKDLVANDGKISFTIELTTPACPLRNQIESEARQAVSMVDGVKEIQIKMGARVRSDGQNRDQMALAVKNIVAIASGKGGVGKSTVAVNVAVSLAQSGAKVGLLDADIYGPNVPTMMGVDGLPPQPGKKMMPAEAYGVKMISIGFMVKPDQPLIWRGPLLHSAIQQFLQDVDWGELDYLVVDLPPGTGDVQLSLAQHVPLSGGVIVTLPQAVSLEDARRGLEMFRKLNVPLLGVIENMSYLELPDGQRMDVFGSGGGEKLAEAANVDFMGGIPMDPSVRISGDNGVPVVVSNPDSAPARALRGLAEKIAAALSVAAIQSHGVSIHLGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WK76</accession>
    <name>A0A0P6WK76_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_18770</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70088">
        <property type="protein sequence ID" value="KPL70088"/>
        <property type="gene ID" value="ADN00_18770"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="59" mass="7404" checksum="4533337B419FB997" modified="2016-01-20" version="1">MKIHFYRSYQAPHWKNATYIQWFTRAKYVIHSFTASLKVGRYAYQMVIEWQNRNPWARY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WMI3</accession>
    <name>A0A0P6WMI3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UPF0033 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_18095</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sulfur carrier protein TusA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL69984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064451.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18095"/>
    <dbReference type="EnsemblBacteria" id="KPL69984">
        <property type="protein sequence ID" value="KPL69984"/>
        <property type="gene ID" value="ADN00_18095"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.110.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001455">
        <property type="entry name" value="TusA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036868">
        <property type="entry name" value="TusA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01206">
        <property type="entry name" value="TusA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF64307">
        <property type="entry name" value="SSF64307"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01148">
        <property type="entry name" value="UPF0033"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UPF0033" evidence="2">
        <location>
            <begin position="9"/>
            <end position="33"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS01148"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL69984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="78" mass="8620" checksum="B0F286FFA1EC14D8" modified="2016-01-20" version="1">MDISVTKSIDERGEVCPVPDVDAKRALAKMNSGDILEVLIDYPLSKERIPANATKDGHEVLAIEETGTSEWRILIKVK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WMJ1</accession>
    <name>A0A0P6WMJ1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Heterodisulfide reductase subunit A-like protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_18160</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL69993.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064464.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18160"/>
    <dbReference type="EnsemblBacteria" id="KPL69993">
        <property type="protein sequence ID" value="KPL69993"/>
        <property type="gene ID" value="ADN00_18160"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2935"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL69993.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="118" mass="12956" checksum="B9A76A5006FD7395" modified="2016-01-20" version="1">MSNKGLLLCVCQGNCPSFQQMNIFEVGNALRREKLVDYVAIHPQLCSKDGDVFLTTLLKGDSTDELYVAACDPTMQVKMFRDAMEAAGFDKQRIHGVDIRNLDTDQAVGAIKQMIAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WML8</accession>
    <name>A0A0P6WML8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_18375</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064507.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70030">
        <property type="protein sequence ID" value="KPL70030"/>
        <property type="gene ID" value="ADN00_18375"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007016">
        <property type="entry name" value="O-antigen_ligase-related"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04932">
        <property type="entry name" value="Wzy_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="42"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="71"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="135"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="190"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="218"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="288"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="403"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="439"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="466"/>
            <end position="485"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL70030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="503" mass="56269" checksum="DF841B6AFB147F6E" modified="2016-01-20" version="1">MIQRLWSGFREWGWTLFVVSMPITSMPLVIRLVGSDTVASPAVPLMAVLLAGWALPLWLKGAKLPSLTLPLLGFALSAFISCAAAFFLLIPPNNDISVLRSEMVALATLLVGMGFYFLTVMMAAGEGKIIKSLRLLNLAGFLVIVWCVAQAVAWRVFDGYPQWMRDFHDLYSRAPLFNNRVTGFALEPSWLANQLNLLFLPFWLAASVKRWSAFPWKFLRWFHVEDGLLAGGLICLLLSLSRVGLLAFMLMTAFLALRLNLWLTRWIEGKLSARNIFRGSNEARRKRLLQILIGGGLVLFYLIAIVGLGVVLSRTDPRMEDLFNFSLGARNPILEYANSLNFSTRIVYWQAGWGTFNDFPWLGVGLGNAGYYFQQKLDPFAWELVEVRNLVYRSGQLLNTKCLWVRILAETGVVGFALFAAWLAVMWKAADALERTPQPLDSIIGLMGKLLIVALIMEGFSVDSFALPYIWFSLGLVTAAAWLNLKKLNVGIAGQREDFTAHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WMT3</accession>
    <name>A0A0P6WMT3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_18950</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70121">
        <property type="protein sequence ID" value="KPL70121"/>
        <property type="gene ID" value="ADN00_18950"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="85" mass="9982" checksum="F13A33D096B5B958" modified="2016-01-20" version="1">MGQHRLKRKWPHVHLRIAKKVSKPEKPILLLARKNLYLHLQGHGHSGKLVLFAYHPQKLLAAGHFPIWDSLLWKDFLFSPLAMIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WQ33</accession>
    <name>A0A0P6WQ33_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Diaminopropionate ammonia-lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_17920</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000043">
        <property type="protein sequence ID" value="KPL70917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17920"/>
    <dbReference type="EnsemblBacteria" id="KPL70917">
        <property type="protein sequence ID" value="KPL70917"/>
        <property type="gene ID" value="ADN00_17920"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2166"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008838">
        <property type="term" value="F:diaminopropionate ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010081">
        <property type="entry name" value="DiNH2opropionate_NH3_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01747">
        <property type="entry name" value="diampropi_NH3ly"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="2" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PALP" evidence="3">
        <location>
            <begin position="5"/>
            <end position="284"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL70917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="314" mass="34100" checksum="FD6BDF0FA17BDB5F" modified="2016-01-20" version="1">MRSFKVLGGSLREQLGDIVFAAATDGNHGRGVAWSAAQMGFKSIIYVHKLTSRSRIQAIEGVGAKVVVVDGNYDDAVRQVYQDAQQHGWQVVSDTAWEGYEEIPQWVMQGYTTMLSEAQEQLAGQGLSKPTHVLVQAGVGSLAAATIGFYYNLFGAERPWSVVVEPTKAACLYRSALIGDGKPYNVEGSLDTIMAGLACGDPNPIAWKILYDCADVFAACPDYVAAKGMRVYSVPLRGDPFLISGESGAVTLGALMYIMEYAGARRLREALHLDRDSQVLLINSEGNTSPDDFRSVVWEGSLPVPEQYKIYVAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WSC9</accession>
    <name>A0A0P6WSC9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_14850</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000036">
        <property type="protein sequence ID" value="KPL73069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063817.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000036.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14850"/>
    <dbReference type="EnsemblBacteria" id="KPL73069">
        <property type="protein sequence ID" value="KPL73069"/>
        <property type="gene ID" value="ADN00_14850"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1832"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL73069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="432" mass="46436" checksum="37B4FB04D539991D" modified="2016-01-20" version="1">MELYQHLLKLQNAGKLIRVGLVGCGQMGSGMVHITRKMPGMETVAIADVNPERPIETFISIGIPRSEIVVTSNYAVASDALSKGKYLVTEDALLLTRLDNIDAVVEATGITEIGAQVAWNCILNKKNITMLNVETDVTVGVFLSRMARKTGCVYTVAAGDEPAVCKMLYDFSSSMGFEVVCLGKGKNNVINYEASPDSCRAEAESKNMNPKMLASFKDGTKTMVEMAAVSNATGLVPDIPGMHGPKVDLPDLTKHFIPQKDGGVLSKSGCVDYSTGNIAPGVFAIVTTDDPRIHADLRFVSMGNGPYYLFLRPFHLCNIETPLAVAEAAIYGETTVVAKDMVSEVVSVAKRDLKAGEVIGGIGSADIFNRIYTYKDARAMKAIPMGIAPGATILKDIPQGTPLTEDAVAPDTSKFVYQLRKMQDEMLHQSAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WSE9</accession>
    <name>A0A0P6WSE9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 3">ATP-dependent Clp protease proteolytic subunit</fullName>
            <ecNumber evidence="2">3.4.21.92</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">Endopeptidase Clp</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">clpP</name>
        <name evidence="4" type="ORF">ADN00_14825</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Cleaves peptides in various proteins in a process that requires ATP hydrolysis. Has a chymotrypsin-like activity. Plays a major role in the degradation of misfolded proteins.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Fourteen ClpP subunits assemble into 2 heptameric rings which stack back to back to give a disk-like structure with a central cavity, resembling the structure of eukaryotic proteasomes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 2 3">Belongs to the peptidase S14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.92" evidence="2"/>
    <dbReference type="EMBL" id="LGCL01000036">
        <property type="protein sequence ID" value="KPL73105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063860.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000036.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14825"/>
    <dbReference type="EnsemblBacteria" id="KPL73105">
        <property type="protein sequence ID" value="KPL73105"/>
        <property type="gene ID" value="ADN00_14825"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1828"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07017">
        <property type="entry name" value="S14_ClpP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00444">
        <property type="entry name" value="ClpP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001907">
        <property type="entry name" value="ClpP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023562">
        <property type="entry name" value="ClpP/TepA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10381">
        <property type="entry name" value="PTHR10381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00574">
        <property type="entry name" value="CLP_protease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00127">
        <property type="entry name" value="CLPPROTEASEP"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 4" id="KW-0645">Protease</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0720">Serine protease</keyword>
    <feature type="active site" description="Nucleophile" evidence="2">
        <location>
            <position position="102"/>
        </location>
    </feature>
    <feature type="active site" evidence="2">
        <location>
            <position position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007039"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00444"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL73105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="199" mass="21908" checksum="565F8E94A1BF1E2C" modified="2016-01-20" version="1">MNNFNSVIPMVIETSGRGERAYDIYSLLLKERIIFLGTPIDDQVANLIVAQLLFLSREDPDKEIQMYINSPGGQIYAGLAIYDTMQMIPNKISTVAVGVTASFGTVLLAAGTKGQRYALPHATIHMHQPLGGAQGQASDIEIQAREILRLKARLNNILSQATGQTMEVIERDTERDFYLDADAAVKYGLVDQVLTPPEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WSY9</accession>
    <name>A0A0P6WSY9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">tRNA dimethylallyltransferase</fullName>
            <ecNumber evidence="5">2.5.1.75</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Dimethylallyl diphosphate:tRNA dimethylallyltransferase</fullName>
            <shortName evidence="5">DMAPP:tRNA dimethylallyltransferase</shortName>
            <shortName evidence="5">DMATase</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Isopentenyl-diphosphate:tRNA isopentenyltransferase</fullName>
            <shortName evidence="5">IPP transferase</shortName>
            <shortName evidence="5">IPPT</shortName>
            <shortName evidence="5">IPTase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">miaA</name>
        <name evidence="9" type="ORF">ADN00_15210</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 5 7">Catalyzes the transfer of a dimethylallyl group onto the adenine at position 37 in tRNAs that read codons beginning with uridine, leading to the formation of N6-(dimethylallyl)adenosine (i(6)A).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5 6">
            <text>adenosine(37) in tRNA + dimethylallyl diphosphate = diphosphate + N(6)-dimethylallyladenosine(37) in tRNA</text>
            <dbReference type="Rhea" id="RHEA:26482"/>
            <dbReference type="Rhea" id="RHEA-COMP:10162"/>
            <dbReference type="Rhea" id="RHEA-COMP:10375"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57623"/>
            <dbReference type="ChEBI" id="CHEBI:74411"/>
            <dbReference type="ChEBI" id="CHEBI:74415"/>
            <dbReference type="EC" id="2.5.1.75"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="5">Monomer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 5 8">Belongs to the IPP transferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.75" evidence="5"/>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72179.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063890.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15210"/>
    <dbReference type="EnsemblBacteria" id="KPL72179">
        <property type="protein sequence ID" value="KPL72179"/>
        <property type="gene ID" value="ADN00_15210"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.744"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052381">
        <property type="term" value="F:tRNA dimethylallyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008033">
        <property type="term" value="P:tRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00185">
        <property type="entry name" value="IPP_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039657">
        <property type="entry name" value="Dimethylallyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018022">
        <property type="entry name" value="IPT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11088">
        <property type="entry name" value="PTHR11088"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00174">
        <property type="entry name" value="miaA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 5 8" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 6" id="KW-0819">tRNA processing</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="5">
        <location>
            <begin position="15"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Interaction with substrate tRNA" evidence="5">
        <location>
            <begin position="38"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="13"/>
            <end position="20"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="site" description="Interaction with substrate tRNA" evidence="5">
        <location>
            <position position="104"/>
        </location>
    </feature>
    <feature type="site" description="Interaction with substrate tRNA" evidence="5">
        <location>
            <position position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001549"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU003783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU003785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL72179.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="322" mass="36139" checksum="3FD200FD57643ED9" modified="2016-01-20" version="1">MSFPEKPLLVIVGPTAVGKTATAIALAKRLDGEIISADSRYFYRGMDIGTAKPTLEERDGVPHYLIDVAEPGDTWSLALFKSAAEEKIANVQQRGKLPILVGGTGQYVRAVIEGWSIPEQEPDTRLREAVTDWGEEIGAEGLHRRLAVVDPEAARQIDYHNQRRTVRALEVIFNTGRRFSDQRTKSSSPYSLFLLGLNLERPLLYQRIDARIESMLIAGLVEETRALLAKGLSPDLPAMSAIGYREVTGYLQGHYDLDEAVRLIKRNTRIFVRRQANWFKESDEKIHWFHATQTTVDEMVAAINQASNWLALQGDNDPQEVI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WT41</accession>
    <name>A0A0P6WT41_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Malate dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_18420</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="5">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="5">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="5">Divalent metal cations. Prefers magnesium or manganese.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the malic enzymes family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064516.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18420"/>
    <dbReference type="EnsemblBacteria" id="KPL70038">
        <property type="protein sequence ID" value="KPL70038"/>
        <property type="gene ID" value="ADN00_18420"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2991"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004471">
        <property type="term" value="F:malate dehydrogenase (decarboxylating) (NAD+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05311">
        <property type="entry name" value="NAD_bind_2_malic_enz"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10380">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015884">
        <property type="entry name" value="Malic_enzyme_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012301">
        <property type="entry name" value="Malic_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037062">
        <property type="entry name" value="Malic_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012302">
        <property type="entry name" value="Malic_NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045213">
        <property type="entry name" value="Malic_NAD-bd_bact_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001891">
        <property type="entry name" value="Malic_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00390">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03949">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000106">
        <property type="entry name" value="ME"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01274">
        <property type="entry name" value="malic"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00919">
        <property type="entry name" value="Malic_M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00331">
        <property type="entry name" value="MALIC_ENZYMES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="malic" evidence="7">
        <location>
            <begin position="19"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="domain" description="Malic_M" evidence="6">
        <location>
            <begin position="164"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="4">
        <location>
            <position position="40"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="4">
        <location>
            <position position="95"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="137"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="138"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR000106-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00919"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL70038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="431" mass="46385" checksum="2A401286C1BB1911" modified="2016-01-20" version="1">MIKITREDALAYHQQDGIPGKLAVVPTKPLLTQRDLSLAYTPGVAYPVLEIEKDPDLAYEYTNKGNLVAVISNGTAILGLGNRGALASKPVMEGKGVLFKKFAAIDTYDLEINALDPQQIIQIVAALAPTFGGINLEDIRSPECFQIEQTLQSMLDIPVFHDDQHGTAIILAAALLNTLELTNRRLDGVKIVFSGAGAAAIACATHLVKIGVPRQHIWMTDIVGLVYEGRKEQMFPEKQAFANGSRPASLTEVLQGADVFIGLSVANVLAPEMLKTMAANPIIFAMANPDPEISYDLAVAARPDAIVATGRSDYPNQINNVLGFPFIFRGALDVRARAINDSMKIAASHALAALARQPVPTEVLRAYNVDHLEFGRAYFVPKPLDLRVCEWEASAVAQAAIDSGAARLALNMPAYRARLQTLAEKGLSAPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WVT5</accession>
    <name>A0A0P6WVT5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Lactoylglutathione lyase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_13880</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methylmalonyl-CoA epimerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063621.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000032.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13880"/>
    <dbReference type="EnsemblBacteria" id="KPL74376">
        <property type="protein sequence ID" value="KPL74376"/>
        <property type="gene ID" value="ADN00_13880"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1353"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd07249">
        <property type="entry name" value="MMCE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017515">
        <property type="entry name" value="MeMalonyl-CoA_epimerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03081">
        <property type="entry name" value="metmalonyl_epim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0456">Lyase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="2">
        <location>
            <begin position="6"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009308"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL74376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="135" mass="14772" checksum="77068342AF64CB2B" modified="2016-01-20" version="1">MAKVTKINHIAIAVNNIEESLAFWQGALGLSLSHIEDVPSQKASVAFIPTGDSEVELVRPTDETTGVAKFLKDRGPGMHHLCLEVDDIDGMLEQLKEKGVRLINETAQVLPGRKMAFIHPKSANGVLVELYQITE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WVV2</accession>
    <name>A0A0P6WVV2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HTH lacI-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_15000</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000036">
        <property type="protein sequence ID" value="KPL73093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063846.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000036.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL73093">
        <property type="protein sequence ID" value="KPL73093"/>
        <property type="gene ID" value="ADN00_15000"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00036">
        <property type="entry name" value="HTHLACI"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="6"/>
            <end position="60"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL73093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="333" mass="36523" checksum="2AD5E34B214917ED" modified="2016-01-20" version="1">MSGSRPTIYDVAKKAGVSISTVSRVLNSPNKVNAETRVAVIDTISELGFIPKAEARARALKNLGRIGVITPFFTEPSFVQRLRGVASVLSSSQYELVVFSVDSITNLNSYLETIPLTRNLDGLILISLQLTAEQAERLSKHNIEVVLIEYPMYSLNCLEIDDQSGGRMAANYLLQKGYTNIAFIGTADTVEYGINPISSRLLGFMNRLSESGITLDAHSIHYASHDIEATRVLAKKVLMQPNPPAAIFAATDLQAIGVLRAAKELNLRVPQDLAVIGFDDLDLAEYFGLTTIHQPLDESGRIAAELLINRIQNPDRPAQHIRLPLTLIERETA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WXB8</accession>
    <name>A0A0P6WXB8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">LexA repressor</fullName>
            <ecNumber evidence="12">3.4.21.88</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="primary">lexA</name>
        <name evidence="16" type="ORF">ADN00_17705</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="16 17" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="16 17">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>Hydrolysis of Ala-|-Gly bond in repressor LexA.</text>
            <dbReference type="EC" id="3.4.21.88"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="12">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 12 13">Belongs to the peptidase S24 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.21.88" evidence="12"/>
    <dbReference type="EMBL" id="LGCL01000043">
        <property type="protein sequence ID" value="KPL70916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17705"/>
    <dbReference type="EnsemblBacteria" id="KPL70916">
        <property type="protein sequence ID" value="KPL70916"/>
        <property type="gene ID" value="ADN00_17705"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2132"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006260">
        <property type="term" value="P:DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009432">
        <property type="term" value="P:SOS response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd06529">
        <property type="entry name" value="S24_LexA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00015">
        <property type="entry name" value="LexA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006200">
        <property type="entry name" value="LexA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039418">
        <property type="entry name" value="LexA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036286">
        <property type="entry name" value="LexA/Signal_pep-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006199">
        <property type="entry name" value="LexA_DNA-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006197">
        <property type="entry name" value="Peptidase_S24_LexA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015927">
        <property type="entry name" value="Peptidase_S24_S26A/B/C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01726">
        <property type="entry name" value="LexA_DNA_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00717">
        <property type="entry name" value="Peptidase_S24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00726">
        <property type="entry name" value="LEXASERPTASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51306">
        <property type="entry name" value="SSF51306"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00498">
        <property type="entry name" value="lexA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 12 13" id="KW-0068">Autocatalytic cleavage</keyword>
    <keyword evidence="4 12" id="KW-0227">DNA damage</keyword>
    <keyword evidence="10 12" id="KW-0234">DNA repair</keyword>
    <keyword evidence="3 12" id="KW-0235">DNA replication</keyword>
    <keyword evidence="8 12" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5 12 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 12" id="KW-0678">Repressor</keyword>
    <keyword evidence="11 12" id="KW-0742">SOS response</keyword>
    <keyword evidence="9 12" id="KW-0804">Transcription</keyword>
    <keyword evidence="7 12" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="LexA_DNA_bind" evidence="15">
        <location>
            <begin position="7"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_S24" evidence="14">
        <location>
            <begin position="128"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="12">
        <location>
            <begin position="32"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="active site" description="For autocatalytic cleavage activity" evidence="12">
        <location>
            <position position="154"/>
        </location>
    </feature>
    <feature type="active site" description="For autocatalytic cleavage activity" evidence="12">
        <location>
            <position position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022491"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022813"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU003991"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF00717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF01726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KPL70916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="240" mass="26983" checksum="40A233029E870C55" modified="2016-01-20" version="1">MARKKAGLSERHKKIMRYLEKFQEDSGYSPSIRQIGESIGVKSTSLVDYYLKQLEEFGYIERDSHVSRSIRLLQPLPTSVGEKVVSAAKSVAATLTDVITIPLQGRIVASAPLPMPASDFNYFDAESGVDIARSLLPPRENVDDLFALEVDGDSMIDAMINDGDIVIMKRAQQANNGEMVAVWLDDNDETTLKYFYKEKDRIRLQPANPTMQPIYVDNPKQVRIMGKVVMVIRQVRNVAM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WYB5</accession>
    <name>A0A0P6WYB5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Chemotaxis protein CheW</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_17320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064307.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17320"/>
    <dbReference type="EnsemblBacteria" id="KPL71446">
        <property type="protein sequence ID" value="KPL71446"/>
        <property type="gene ID" value="ADN00_17320"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.527"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039315">
        <property type="entry name" value="CheW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036061">
        <property type="entry name" value="CheW-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002545">
        <property type="entry name" value="CheW-lke_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22617">
        <property type="entry name" value="PTHR22617"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01584">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00260">
        <property type="entry name" value="CheW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50341">
        <property type="entry name" value="SSF50341"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50851">
        <property type="entry name" value="CHEW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CheW-like" evidence="1">
        <location>
            <begin position="2"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50851"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL71446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="149" mass="16428" checksum="EC584328B73B030D" modified="2016-01-20" version="1">MERQVVVFELANEQYGVDISTVEGIIKLQTITRMPQAPAYVEGVTNLRGNVVPVIDLRTRFDLPKVEPTHDTRIVVAYMDHSKVGMVVDAVSQVLVVPEDAIEPPPPMVTTINSAFITGIAKLQNQLVILLDLGEVLSIQERKELQAIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WYC6</accession>
    <name>A0A0P6WYC6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Histidinol-phosphate aminotransferase</fullName>
            <ecNumber evidence="3">2.6.1.9</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Imidazole acetol-phosphate transaminase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3" type="primary">hisC</name>
        <name evidence="5" type="ORF">ADN00_17435</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>2-oxoglutarate + L-histidinol phosphate = 3-(imidazol-4-yl)-2-oxopropyl phosphate + L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:23744"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57766"/>
            <dbReference type="ChEBI" id="CHEBI:57980"/>
            <dbReference type="EC" id="2.6.1.9"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 3">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Amino-acid biosynthesis; L-histidine biosynthesis; L-histidine from 5-phospho-alpha-D-ribose 1-diphosphate: step 7/9.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.6.1.9" evidence="3"/>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064327.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17435"/>
    <dbReference type="EnsemblBacteria" id="KPL71464">
        <property type="protein sequence ID" value="KPL71464"/>
        <property type="gene ID" value="ADN00_17435"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.555"/>
    <dbReference type="UniPathway" id="UPA00031">
        <property type="reaction ID" value="UER00012"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004400">
        <property type="term" value="F:histidinol-phosphate transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000105">
        <property type="term" value="P:histidine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01023">
        <property type="entry name" value="HisC_aminotrans_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005861">
        <property type="entry name" value="HisP_aminotrans"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01141">
        <property type="entry name" value="hisC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="2 3 5" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-0368">Histidine biosynthesis</keyword>
    <keyword evidence="3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="4">
        <location>
            <begin position="35"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="3">
        <location>
            <position position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022576"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL71464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="374" mass="41285" checksum="DF0B4D2B949FD464" modified="2016-01-20" version="1">MSRVRLAPRFENFPPYTPIEPFEVLSARLGLPPEKIIKVDANENPYGPAPAVKEALANLRWANIYPDPESRALRAALSDFTGAPAENLLPGAGADELIDLILRLVLEPGDVVLNFPPTFGMYPFDTLLNAGQVIDVPRLPDFSLDLPAIRRAVEEHQPKAMFLTTPNNPDGHFPPAAVLDELLELPLLVVVDEAYIEFTREGGRLGENLSRIRSVPQRENLIVLRTFSKWAGLAGLRVGYGAFPTWMMPALWAAKQPYNVNVAASEAALASLRSLDFLAANVERLKAERERLFGLLQSVPYLTPYPSQANFILCGVKQIPASQLKASLAARGILVRYYNTPYLRDMIRISIGRPAESDAVIAALRELAEEKSEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZH2</accession>
    <name>A0A0P6WZH2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 3">Acyl carrier protein</fullName>
            <shortName evidence="1">ACP</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">acpP</name>
        <name evidence="5" type="ORF">ADN00_15300</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 3">Carrier of the growing fatty acid chain in fatty acid biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="1 3">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="PTM">
        <text evidence="1">4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by AcpS. This modification is essential for activity because fatty acids are bound in thioester linkage to the sulfhydryl of the prosthetic group.</text>
    </comment>
    <comment type="PTM">
        <text evidence="3">4'-phosphopantetheine is transferred from CoA to a specific serine of apo-ACP by acpS.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the acyl carrier protein (ACP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72196.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063908.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15300"/>
    <dbReference type="EnsemblBacteria" id="KPL72196">
        <property type="protein sequence ID" value="KPL72196"/>
        <property type="gene ID" value="ADN00_15300"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000036">
        <property type="term" value="F:acyl carrier activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1200.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01217">
        <property type="entry name" value="Acyl_carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036736">
        <property type="entry name" value="ACP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003231">
        <property type="entry name" value="Acyl_carrier"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009081">
        <property type="entry name" value="PP-bd_ACP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20863">
        <property type="entry name" value="PTHR20863"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00550">
        <property type="entry name" value="PP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47336">
        <property type="entry name" value="SSF47336"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00517">
        <property type="entry name" value="acyl_carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50075">
        <property type="entry name" value="CARRIER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1" id="KW-0275">Fatty acid biosynthesis</keyword>
    <keyword evidence="1" id="KW-0276">Fatty acid metabolism</keyword>
    <keyword evidence="1" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="1" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="1 2 3" id="KW-0596">Phosphopantetheine</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Carrier" evidence="4">
        <location>
            <begin position="2"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="modified residue" description="O-(pantetheine 4'-phosphoryl)serine" evidence="1 2">
        <location>
            <position position="37"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01217"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00258"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL72196.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="78" mass="8941" checksum="9EB8E4086E6A1274" modified="2016-01-20" version="1">MGDTFEAVKEVIVEVMKIDGKDLSMETRFIEDLQADSMDQFFLIDGFCEKFDINISDEDARKIKNVKDAVEFIDKAKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X2T8</accession>
    <name>A0A0P6X2T8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">DNA repair protein RecO</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6 7">Recombination protein O</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="7" type="primary">recO</name>
        <name evidence="9" type="ORF">ADN00_10770</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Involved in DNA repair and RecF pathway recombination.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the RecO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063002.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10770"/>
    <dbReference type="EnsemblBacteria" id="KPL77037">
        <property type="protein sequence ID" value="KPL77037"/>
        <property type="gene ID" value="ADN00_10770"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006310">
        <property type="term" value="P:DNA recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00201">
        <property type="entry name" value="RecO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037278">
        <property type="entry name" value="ARFGAP/RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022572">
        <property type="entry name" value="DNA_rep/recomb_RecO_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003717">
        <property type="entry name" value="RecO"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042242">
        <property type="entry name" value="RecO_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33991">
        <property type="entry name" value="PTHR33991"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02565">
        <property type="entry name" value="RecO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11967">
        <property type="entry name" value="RecO_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="SSF50249"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57863">
        <property type="entry name" value="SSF57863"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00613">
        <property type="entry name" value="reco"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="4 7" id="KW-0233">DNA recombination</keyword>
    <keyword evidence="5 7" id="KW-0234">DNA repair</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DNA_rep/recomb_RecO_N" evidence="8">
        <location>
            <begin position="9"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021310"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00033409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF11967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL77037.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="261" mass="30037" checksum="F4ED2AD6F737E446" modified="2016-01-20" version="1">MPNEVRSLRVEGVVLRHSDWGEADRLLLVYTRERGKLRALAKGVRKLRSRKAGHLEPFTRVALMLARGRDMWIVTQAETVEAYLPLRDNLLKLGQAATVLELVDRFGYEEGEDPGLYQLLTATLRRICEEEDAFLALRYFDLRVLDLFGFRPQLFHCARCGAEIKAEDQFFSALQGGVLCPRCGPQDPTARPASVEALRFLRHIQRSNYTESKRANIPAPIRSEMEQLLQYYFTYHLERKLNSPDFLRRIRQNGRNGSAEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X391</accession>
    <name>A0A0P6X391_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_09400</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77329.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062735.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09400"/>
    <dbReference type="EnsemblBacteria" id="KPL77329">
        <property type="protein sequence ID" value="KPL77329"/>
        <property type="gene ID" value="ADN00_09400"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00130">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001610">
        <property type="entry name" value="PAC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000700">
        <property type="entry name" value="PAS-assoc_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013656">
        <property type="entry name" value="PAS_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013767">
        <property type="entry name" value="PAS_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013655">
        <property type="entry name" value="PAS_fold_3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00989">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08447">
        <property type="entry name" value="PAS_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08448">
        <property type="entry name" value="PAS_4"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00086">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SMART" id="SM00091">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="SSF55785"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00229">
        <property type="entry name" value="sensory_box"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50113">
        <property type="entry name" value="PAC"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PAS" evidence="4">
        <location>
            <begin position="46"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="5">
        <location>
            <begin position="126"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="4">
        <location>
            <begin position="181"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="4">
        <location>
            <begin position="328"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="5">
        <location>
            <begin position="385"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="4">
        <location>
            <begin position="438"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="4">
        <location>
            <begin position="558"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="5">
        <location>
            <begin position="626"/>
            <end position="682"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="5">
        <location>
            <begin position="768"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="4">
        <location>
            <begin position="821"/>
            <end position="891"/>
        </location>
    </feature>
    <feature type="domain" description="PAC" evidence="5">
        <location>
            <begin position="889"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="domain" description="Histidine kinase" evidence="3">
        <location>
            <begin position="971"/>
            <end position="1192"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="13"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="937"/>
            <end position="971"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50113"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL77329.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="1193" mass="135416" checksum="6B2764ACAF0B3DFB" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X3J6</accession>
    <name>A0A0P6X3J6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Mg-protoporphyrin IX chelatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_13615</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Mg-chelatase subunits D/I family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13615"/>
    <dbReference type="EnsemblBacteria" id="KPL74381">
        <property type="protein sequence ID" value="KPL74381"/>
        <property type="gene ID" value="ADN00_13615"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1299"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045006">
        <property type="entry name" value="CHLI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041628">
        <property type="entry name" value="ChlI/MoxR_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000523">
        <property type="entry name" value="Mg_chelatse_chII-like_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32039">
        <property type="entry name" value="PTHR32039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17863">
        <property type="entry name" value="AAA_lid_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01078">
        <property type="entry name" value="Mg_chelatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="5">
        <location>
            <begin position="32"/>
            <end position="216"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005799"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00030759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL74381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="355" mass="39547" checksum="61949CA9C380E71D" modified="2016-01-20" version="1">MGIAETLPYPFLGLVGQDEMKLSLILSLVNPMLGGVLLVGPRGTGKTTAVRSLVNLIPDVPRSLCVYGCTEADVEAGGMDAVCPDCARRFAEGKPLSCMEPARLVELPLNARLEDVIGGVDERSLLQNRLRLKKGILAQADQNLLYLDEVNLLQDDIIDAVLDAAAQGSFTVRRGPLSATYRSRFTLIGSMNPEEGNLRPQILDRFGLRVIVKGLEDEKERKTAYERTVAYRSNPHLFTSLFEEESIQARQEIQAARKLVRTVSIPEKIARSGIQLIQQLKIDSLRAEITLFESAKAHAAADGRKRVEPEDLKAVIPMALRLRRSKYMVDYIKDREREDAELHKYLDKVITNARP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X4I3</accession>
    <name>A0A0P6X4I3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Rieske domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_13270</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000031">
        <property type="protein sequence ID" value="KPL74811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063504.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000031.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13270"/>
    <dbReference type="EnsemblBacteria" id="KPL74811">
        <property type="protein sequence ID" value="KPL74811"/>
        <property type="gene ID" value="ADN00_13270"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1136"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051537">
        <property type="term" value="F:2 iron, 2 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.102.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017941">
        <property type="entry name" value="Rieske_2Fe-2S"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036922">
        <property type="entry name" value="Rieske_2Fe-2S_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044043">
        <property type="entry name" value="VanA_C_cat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00355">
        <property type="entry name" value="Rieske"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19112">
        <property type="entry name" value="VanA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50022">
        <property type="entry name" value="SSF50022"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51296">
        <property type="entry name" value="RIESKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0408">Iron</keyword>
    <keyword evidence="4" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rieske" evidence="5">
        <location>
            <begin position="6"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51296"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL74811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="329" mass="37697" checksum="762F55CC97718607" modified="2016-01-20" version="1">MIRNQWYVVLESDEVKTGMPVGVTRLGEKMVFWRDGQGKASCMVDVCPHLGAPLSLGKVKDGHIACPFHGFEYDTSGQCVVLPAYGSQGKIPKALRVKAYPVHEAHGLIWIWWGENVPKDLQPPRFFESLENERFVFGRFRDHWPVHYSRMAENQLDVMHLPFVHHNTIGRGNRSVVDGPYIELDEGLMNVWVMNRLDDGSPVKKPKEVSRPDRRPFLQFRFPNLWHNWIAEDIRIVIAFVPVDDENTIMMGRFYQKAVRFPLAAQLFNLSGVIGSRVIANQDKRVVSRQVPVKTSLHMGEKMMSGDYGILTYRTERNRLKALAGQAED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5A4</accession>
    <name>A0A0P6X5A4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Daunorubicin ABC transporter ATPase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_10750</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062998.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77033">
        <property type="protein sequence ID" value="KPL77033"/>
        <property type="gene ID" value="ADN00_10750"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2625"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="4"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="47"/>
            <end position="54"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL77033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="324" mass="36188" checksum="6BD324FBFB664430" modified="2016-01-20" version="1">MKAIEVDHLQRIFRPTIGVFRRTTKEVLAVEDVSFEVGAGELFGLLGPNGAGKTTTVKMLTTLLLPTRGGARIMGLDVVKNATEVQKRIGFIFGGERGLYWRLSGIDNLRYFGSLYHVDPDVSKKRIPYLLELVGLKDRGNERVEGYSRGMKQRLHVARTLLHDPQVLFLDEPTIGLDPVGAREFRAVIKNLQSENKTILLTTHYMFEADALCQRIAVIDHGNLVALDTPEALKRFVSDLSVVEVEVYGIPDELVQKIKAQPYVDSVHIENREQKQLLQVQSLRGAEAVPDLVTLLNGLRVGRVIVREPTLEDAYVRLVGGKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5T0</accession>
    <name>A0A0P6X5T0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FAD-binding FR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_08915</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062648.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08915"/>
    <dbReference type="EnsemblBacteria" id="KPL77253">
        <property type="protein sequence ID" value="KPL77253"/>
        <property type="gene ID" value="ADN00_08915"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013112">
        <property type="entry name" value="FAD-bd_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013130">
        <property type="entry name" value="Fe3_Rdtase_TM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08022">
        <property type="entry name" value="FAD_binding_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01794">
        <property type="entry name" value="Ferric_reduct"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="SSF52343"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="SSF63380"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="42"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="80"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="120"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="155"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="186"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="6">
        <location>
            <begin position="210"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL77253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="446" mass="50945" checksum="550DA9D222186355" modified="2016-01-20" version="1">MKKETLRPLLVFLFFLLVFSPLLVMPFVEPGLSRGWQRESSIILGFVGLTLAGWQLAPISRFTPAQKLFNLDRLYTFHHILSVMSAVFVTVHYLLLLFNFEAGFGINNWALGLLNIFTAPLRAQMGVLSLLAYLLITITSVFRKPLRMDYDVWRILHDIFTLILVAAGLTHALLVGNYTAAPAMKALLWFETALWILVALYIRVFKPLDQLRHPYNIIEVREEVENAFTLALEPQGFALPEFHAGQVAWLTVRRSPFSLRRHPFSVSSSTHNRQHIEFTIKELGDFTRTVRNLKAGETVYIDGPFGYHNITHPNHKGMVFLVGGIGIAPAMSALRSMADGNDPRPVYLFYGNNHLDHLVFGEELKQLEARLPNFRNHVVLEHPPADWHGYKGFITSDLVRKELPQNFRELNFFICGPQPMMKPMRKILKTLEVPAGNVHFEEFNMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5V2</accession>
    <name>A0A0P6X5V2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LytR_cpsA_psr domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_09260</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the LytR/CpsA/Psr (LCP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77308.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062709.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77308">
        <property type="protein sequence ID" value="KPL77308"/>
        <property type="gene ID" value="ADN00_09260"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4086"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004474">
        <property type="entry name" value="LytR_CpsA_psr"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03816">
        <property type="entry name" value="LytR_cpsA_psr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="domain" description="LytR_cpsA_psr" evidence="3">
        <location>
            <begin position="98"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006068"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF03816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL77308.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="330" mass="36369" checksum="6C6DAE5EFB6A617C" modified="2016-01-20" version="1">MKTFLKFVIPTLILAVLVVGIIAVPRIYRAPLGEPLALVQNEQPLPEPTVLMADQQPQQTGPTAVPTATPPGTCGRTGAINLLMLGVDASIGVPPHGADAIRLVRVDFDNAKVTSMAFSRDLEVTLEDGETLNLCQFFKHACECTNGDPRIKTTNASCKVAQLMLDTYGLQPDHYFTITLDEFIPMIDLIGGIDVRNPEVFTNERGTTFQEGVLHLDGKASADFLRSLQPGGDPARILRQNLVLDALRSKLLTFDVLTKIPELYAHFEQLIVTDLSPEEIAQLSCMLKEVSPEAITVYEMDKDQQIMDSKGVRYPYTGDIKAYLQELFTH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7L8</accession>
    <name>A0A0P6X7L8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_19175</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70153.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064648.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_19175"/>
    <dbReference type="EnsemblBacteria" id="KPL70153">
        <property type="protein sequence ID" value="KPL70153"/>
        <property type="gene ID" value="ADN00_19175"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="SSF53254"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70153.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="202" mass="23072" checksum="E0447AA22FBFC830" modified="2016-01-20" version="1">MQTQSGAPGFRTEETLLNAPHDRSVALLLRHSARYPIFDDFDPYQAQLTPAGVRMAEDLGRWMGRQGMRLGGFYSSPVGRCIDTAMGIARGAGYWANVRPEEKLSFPYLQPTRRNIIHFRASDPLPERVVEAMRFMLRRNGGLSTFQVFVSHDSYLACILAHVFLEPIEDHWPEFLEGMAMWREGDEVILSWRGRTKRISGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X8M7</accession>
    <name>A0A0P6X8M7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_03000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000014">
        <property type="protein sequence ID" value="KPL79313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061478.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000014.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03000"/>
    <dbReference type="EnsemblBacteria" id="KPL79313">
        <property type="protein sequence ID" value="KPL79313"/>
        <property type="gene ID" value="ADN00_03000"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2009"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002939">
        <property type="entry name" value="DnaJ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008971">
        <property type="entry name" value="HSP40/DnaJ_pept-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01556">
        <property type="entry name" value="DnaJ_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="SSF46565"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49493">
        <property type="entry name" value="SSF49493"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="1">
        <location>
            <begin position="5"/>
            <end position="70"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="309" mass="34421" checksum="C94F156BCCAE3D23" modified="2016-01-20" version="1">MEYKDYYKVLGVSRGATPDEIKKAYRNLAKKYHPDRNPGDKAAEDRFKDVNEAYEVLSDAQKRARYDQLGESYSQWQTTGRPGSFNWEDWFASAPGAAGASGTRVDMGNMEDMFGRAGGFSDFFQFIFGGMGAPDVRTTRRGARAAAPRPRTIEHPLTISFYEAYHGGSRTIQIDDRRMEVKIPAGARTGTKIRMAGVGPNQTDIYLVIEVSPDPRYERKDDDLYTDVSVDMFTAVLGGQVLTPTPGGDVLLTIPAGTQPGQTFRLAQRGMPKLRNPQQHGDLYARVRVSIPRNLSAQQKELLIKARQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X930</accession>
    <name>A0A0P6X930_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Amino_oxidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_12130</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76085.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063281.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12130"/>
    <dbReference type="EnsemblBacteria" id="KPL76085">
        <property type="protein sequence ID" value="KPL76085"/>
        <property type="gene ID" value="ADN00_12130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016116">
        <property type="term" value="P:carotenoid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002937">
        <property type="entry name" value="Amino_oxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045892">
        <property type="entry name" value="CrtISO-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46313">
        <property type="entry name" value="PTHR46313"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01593">
        <property type="entry name" value="Amino_oxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0934">Plastid</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amino_oxidase" evidence="3">
        <location>
            <begin position="12"/>
            <end position="404"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF01593"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL76085.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="500" mass="55878" checksum="8EA97D6CC8D338F7" modified="2016-01-20" version="1">MPTSIIIIGAGIGGLSTAIYAQMNGFKTQIFEQHAIPGGVCTGWKRKGYTFDGCIHHLAGSQPGSSLYRMWQELGIMPHPIHYPEDLIAIEDTNGRRMIVYANIDRFEQHLLELSPQDKAPILEFTQAARQFVRLNLMDMLLASPIQMLKILPSIGLLKKWTSLTLDQFAQRFSDPFLRRAFTQIQYDFPNIPCMIALMFLAGVHSRFLGFPAGGGLEFAHKLEQRYLHLGGQIHYHSPVEKILVDSNGGSNRAVGVQLSDGSQHMADFVISNADGYHTIYNMLSGKFTTPLIEKYYQNPPANQVMSLHISLGVAADFLQQPHALVLWLPEPVRIAGEMTDRLDLEFYNFAPEMAPQGKSVVKVTCLSSYEYWAAAKANGQAEYQAEKERVAELVVSQLQHRFPGLQQQVEVIDVATPLTTERFVGSHHGYQAWPVPDQSPLEILQGKGLSRTLPGLDHFYMVGQWAGGLGLPNVAVMGRKIIQELCKQTHRPFQTKPLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X969</accession>
    <name>A0A0P6X969_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="7 10">Threonine synthase</fullName>
            <ecNumber evidence="6 10">4.2.3.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">ADN00_17725</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="14 15" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="14 15">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3 10">Catalyzes the gamma-elimination of phosphate from L-phosphohomoserine and the beta-addition of water to produce L-threonine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 10">
            <text>H2O + O-phospho-L-homoserine = L-threonine + phosphate</text>
            <dbReference type="Rhea" id="RHEA:10840"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57590"/>
            <dbReference type="ChEBI" id="CHEBI:57926"/>
            <dbReference type="EC" id="4.2.3.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2 10 11">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="4 10">Amino-acid biosynthesis; L-threonine biosynthesis; L-threonine from L-aspartate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="5 10">Belongs to the threonine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.3.1" evidence="6 10"/>
    <dbReference type="EMBL" id="LGCL01000043">
        <property type="protein sequence ID" value="KPL70885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064385.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000043.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17725"/>
    <dbReference type="EnsemblBacteria" id="KPL70885">
        <property type="protein sequence ID" value="KPL70885"/>
        <property type="gene ID" value="ADN00_17725"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2136"/>
    <dbReference type="UniPathway" id="UPA00050">
        <property type="reaction ID" value="UER00065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004795">
        <property type="term" value="F:threonine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009088">
        <property type="term" value="P:threonine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="PLP-dep"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000634">
        <property type="entry name" value="Ser/Thr_deHydtase_PyrdxlP-BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004450">
        <property type="entry name" value="Thr_synthase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026260">
        <property type="entry name" value="Thr_Synthase_bac/arc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="Trypto_synt_PLP_dependent"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF038945">
        <property type="entry name" value="Thr_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="SSF53686"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00260">
        <property type="entry name" value="thrC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00165">
        <property type="entry name" value="DEHYDRATASE_SER_THR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10 14" id="KW-0456">Lyase</keyword>
    <keyword evidence="9 10 11" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8 10" id="KW-0791">Threonine biosynthesis</keyword>
    <feature type="domain" description="PALP" evidence="13">
        <location>
            <begin position="23"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Pyridoxal phosphate binding" evidence="11">
        <location>
            <begin position="188"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="317"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="12">
        <location>
            <position position="62"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000051"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00003648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00005517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013028"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00018679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR038945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR038945-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR038945-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KPL70885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="352" mass="36673" checksum="9031F65DA2478609" modified="2016-01-20" version="1">MAYNGVLAQYGHLMDLPAHTLPITLLEGNTPLIPMPGLAAELGGGFELYVKFEGLNPTGSFKDRGMTAAVSEAAGRGAKAVICASTGNTAASAAAYASRAGMRAVVIIPDGKVATGKLAGAMAYGAEVIQIKGSFDDALNLVVQISQRHPIALVNSLNPYRLEGQKSSAFEICDTLGAAPDWLCLPVGNAGNITSYWMGFRQYNTLKQSGLPRILGVQAEGSAPLVIGHPVEHPETVCTAIRIGKPARGEEALQAAEESNGRIIAMSDDAILAAQRQLASHGVWVEPASAAGVCGLVHQIRTGQLDPKGKRIVAICTGHGLKDPDIITRQAATPRALPATLAAMEEAILGER</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9A1</accession>
    <name>A0A0P6X9A1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_05290</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78670.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061930.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78670">
        <property type="protein sequence ID" value="KPL78670"/>
        <property type="gene ID" value="ADN00_05290"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78670.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="189" mass="21204" checksum="6BA9BD667981F721" modified="2016-01-20" version="1">MNESALVPVPDLQQLSLVISPRAARAQMLEMAAMLSLRGTLRVFDGGNMLDVYRMAKSIRRRTPRVEEALERIHLSRAFSCYQVVALLSEASAGTAPLLVCDLLGTFYDENVTLKEAHRLLEICLRHLRRLSSEAIVVVSARPPRLNPERVALLERLMEEIQNVREIVELEEEQAPALPTGIVQPPLPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9W9</accession>
    <name>A0A0P6X9W9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_06490</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78853.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062148.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06490"/>
    <dbReference type="EnsemblBacteria" id="KPL78853">
        <property type="protein sequence ID" value="KPL78853"/>
        <property type="gene ID" value="ADN00_06490"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1802"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="26"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="282"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="329"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="375"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="24"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="314"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL78853.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="413" mass="43427" checksum="37AB67D0357D2B8C" modified="2016-01-20" version="1">MNLKNIAPAFIEALESLNANKMRSGLTILGIVIGVGAVIAMLALGEGVQASITGEINSVGSNLIFVVEGNQTEEVRNARPLTLSDVKAISDPYQAPSVLAAVPAVSGSVEISYSGVTEQSSLTGTLPEYQQVRSLELLEGDFITSENQNGIASVAVIGVDVADTLYGRQEQVVGESIRLNGQLFRVIGLLKSQGGNAMGSQDNIVIVPFSTAQSRLLSRENHEQVDVIYAQAIDADSTTAAVSEITDTLRARHRLSVEDPDDFTIFTQDSFLDMANTITSTVIIFLGGVAGISLLVGGIGIMNIMLVSVTERTREIGLRKALGAKKSDIMIQFLIESGLLSLLGGILGILLGALLSFAVSQIANAAGTPLNPAMTIQSVLLATLFSAAVGIFFGIYPANRAASLEPVEALRHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XA18</accession>
    <name>A0A0P6XA18_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">DUF4325 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77051.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063021.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77051">
        <property type="protein sequence ID" value="KPL77051"/>
        <property type="gene ID" value="ADN00_10870"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2653"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025474">
        <property type="entry name" value="DUF4325"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14213">
        <property type="entry name" value="DUF4325"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4325" evidence="1">
        <location>
            <begin position="275"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77051.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="343" mass="39434" checksum="96ED2EA528123602" modified="2016-01-20" version="1">MSQKFDDITNFILRHVREYPSEVTRMAVDHFGISRQAVNRYMKYLVKEGVLSESGNTRSRKYTINPILNEYWDLNVKENQEEDRVWRNLLKPYTTNLPKNIQEICQYGFTEIYNNVIDHSESQTAVISLTIYPDWIRITVKDNGVGIFNKIQSHFNLDDPMHAILELSKGKLSTDPGRHSGEGIFFTSRMFDTFSIVSSHLIFCHSKEGGMDALFEEKEFSAGTTVVMETSLFSSATTEEIFNEYSINGGFGFDRTVIPVFLGGYGDENLVSRSQARRLLARINRFKLIVFDFNKVEMIGQAFADEIFRVYANENPAIKLMYVNVNKKVEGMIKRVIDARIGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XA27</accession>
    <name>A0A0P6XA27_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methylmalonyl-CoA carboxyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_16055</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064056.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16055"/>
    <dbReference type="EnsemblBacteria" id="KPL72006">
        <property type="protein sequence ID" value="KPL72006"/>
        <property type="gene ID" value="ADN00_16055"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3645"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009317">
        <property type="term" value="C:acetyl-CoA carboxylase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003989">
        <property type="term" value="F:acetyl-CoA carboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034733">
        <property type="entry name" value="AcCoA_carboxyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000438">
        <property type="entry name" value="Acetyl_CoA_COase_Trfase_b_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029045">
        <property type="entry name" value="ClpP/crotonase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011763">
        <property type="entry name" value="COA_CT_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011762">
        <property type="entry name" value="COA_CT_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01039">
        <property type="entry name" value="Carboxyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01070">
        <property type="entry name" value="ACCCTRFRASEB"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52096">
        <property type="entry name" value="SSF52096"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50989">
        <property type="entry name" value="COA_CT_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50980">
        <property type="entry name" value="COA_CT_NTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="CoA carboxyltransferase N-terminal" evidence="1">
        <location>
            <begin position="3"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="domain" description="CoA carboxyltransferase C-terminal" evidence="2">
        <location>
            <begin position="263"/>
            <end position="498"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL72006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="516" mass="56304" checksum="B264CC0F5E8124E1" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XA31</accession>
    <name>A0A0P6XA31_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">RNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_10925</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063031.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10925"/>
    <dbReference type="EnsemblBacteria" id="KPL77060">
        <property type="protein sequence ID" value="KPL77060"/>
        <property type="gene ID" value="ADN00_10925"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2665"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="SSF54928"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RRM" evidence="2">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="130" mass="13451" checksum="470E46A327A55ACE" modified="2016-01-20" version="1">MNIYVGNLPYSVSEDDVRQAFEAFGEVASVSMIKDKMTGQPRGFGFVEMNDDGEAQAAIDALNGKDLKGRAMVVNAARPREERPMGGGGGRGGFGGGNRRPGGGGGFGGPGGGNRRPGGPGGQKPPRREW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAD2</accession>
    <name>A0A0P6XAD2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Response regulatory domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_04005</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79054.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061673.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04005"/>
    <dbReference type="EnsemblBacteria" id="KPL79054">
        <property type="protein sequence ID" value="KPL79054"/>
        <property type="gene ID" value="ADN00_04005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.270">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043128">
        <property type="entry name" value="Rev_trsase/Diguanyl_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="2">
        <location>
            <begin position="7"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79054.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="287" mass="32450" checksum="C23C1D39A051FDD7" modified="2016-01-20" version="1">MKDIAPTILIVEDDQDIAEMLGAFLRSAGYQVVTENWGEDGVRSARAKRPDLVILDVRLPDIDGFEVLERMREHVSTRYTPVIFLTERREREARLQGLALHADDYITKPFDVEELLLRVQNTLARAQRAAVQHPVSGLVMGTALKERLDRLAGQQDWSALVMRVENSQQFREIYGFIAADDLLRATTLIIRDIIQPSDALLPFLGHLDDWCVLAGVPRERAADVKARIEQKLEQSFQYFYRDQDLSAGTFEGKRLTVSVQLLAARAAWGDGQAIVDECSRLCKQDGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAD9</accession>
    <name>A0A0P6XAD9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Macrolide ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_04060</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061682.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79063">
        <property type="protein sequence ID" value="KPL79063"/>
        <property type="gene ID" value="ADN00_04060"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd03255">
        <property type="entry name" value="ABC_MJ0796_LolCDE_FtsE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017911">
        <property type="entry name" value="MacB_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="6"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="42"/>
            <end position="49"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL79063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="226" mass="25206" checksum="0558828A00BF354B" modified="2016-01-20" version="1">MDEWVIETRDLTKTYQMGEVQVHALCGVDLRVRRGEVLAIMGPSGSGKSTMMNILGCLDRPTSGQYWLDGEDVSSMSDDQLADIRNRKVGFVFQSFMLLPRHSALGNVELPMRYAGVRAERMQRAKEALQAVGLADRMYHKPSELSGGQQQRVAIARALVNRPSIIMADEPTGNLDSKSGKEIMELLMDLNRQRGTTVILITHDPVIGEQAQRVVHLMDGRVEERA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XB68</accession>
    <name>A0A0P6XB68_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_10400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062934.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76981">
        <property type="protein sequence ID" value="KPL76981"/>
        <property type="gene ID" value="ADN00_10400"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="274" mass="31356" checksum="D815A1F34E1DB69D" modified="2016-01-20" version="1">MFVIIWLVGVFVLGAAIMVVLALQGFEIRPKAFRAPTSRPAPEPQPLPEDHLPLPVRDYLRASLCGAAALPENAAVWGRAQVRYKRRWLPMRFKTLYLPGSAFYRRWQGSWYGMPVARGEEYLRGGRGVIRMSRRAQNGDTIDHWNLLKLWVEAVWHPSIYALDSRARWEGLSNLAAELVVPYNGGETRLTAFFDPQTNLLSHFTALQPRSGYARPQLWRVDFSDWERINGVMLPSQAVFRWEDDPQPYARWKIDGAAVNINAARWLGGARLEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBK5</accession>
    <name>A0A0P6XBK5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">ADN00_16665</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72101.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064170.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16665"/>
    <dbReference type="EnsemblBacteria" id="KPL72101">
        <property type="protein sequence ID" value="KPL72101"/>
        <property type="gene ID" value="ADN00_16665"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3776"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011096">
        <property type="entry name" value="FTP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023612">
        <property type="entry name" value="Peptidase_M4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001570">
        <property type="entry name" value="Peptidase_M4_C_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013856">
        <property type="entry name" value="Peptidase_M4_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07504">
        <property type="entry name" value="FTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01447">
        <property type="entry name" value="Peptidase_M4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02868">
        <property type="entry name" value="Peptidase_M4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00730">
        <property type="entry name" value="THERMOLYSIN"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132968" evidence="8">
        <location>
            <begin position="34"/>
            <end position="1176"/>
        </location>
    </feature>
    <feature type="domain" description="FTP" evidence="11">
        <location>
            <begin position="108"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M4" evidence="9">
        <location>
            <begin position="282"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M4_C" evidence="10">
        <location>
            <begin position="370"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="352"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR623612-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KPL72101.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="1176" mass="128871" checksum="395389D1567BBAEC" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBL6</accession>
    <name>A0A0P6XBL6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GH16 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_16340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16340"/>
    <dbReference type="EnsemblBacteria" id="KPL72119">
        <property type="protein sequence ID" value="KPL72119"/>
        <property type="gene ID" value="ADN00_16340"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004553">
        <property type="term" value="F:hydrolase activity, hydrolyzing O-glycosyl compounds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000757">
        <property type="entry name" value="GH16"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00722">
        <property type="entry name" value="Glyco_hydro_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="SSF49899"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51762">
        <property type="entry name" value="GH16_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GH16" evidence="1">
        <location>
            <begin position="7"/>
            <end position="275"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51762"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="275" mass="31683" checksum="466C6A0CFE2E5857" modified="2016-01-20" version="1">MNQWSLSSMTENFIAYDKVVFFDDFIGNELDRTKWNVEITGEIYNKEQQAYIDSEKTIYFLPEYESSQGVLVIHPRYHKGFETTQKQKLDFLSGRINTRSKFEFQEGCVSARIKVPRGEGLWPAFWALGSSGKWPGCGEIDIMEYVGESDWTCASVHGPGYSGEAGLTNRKFMPAENDATHWHVYSMIFTKDLILFEIDGETIYRVTRPMVEFFGEWVFDNQKFLILNFALGGVFPYKTNGINSPYYGIPQATVEAIQRDEIKLLVDWVKVTITK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XC50</accession>
    <name>A0A0P6XC50_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_08045</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77828.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062474.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77828">
        <property type="protein sequence ID" value="KPL77828"/>
        <property type="gene ID" value="ADN00_08045"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="46"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77828.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="76" mass="8890" checksum="1613E348F1158F4F" modified="2016-01-20" version="1">MNVRLTQQFEIAFWDLVTQSLSQSRLVRYFVYHFYHLFHQQPPEKLILTFAWVGAAGFFTGAVLGALLILLQWGMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XCB1</accession>
    <name>A0A0P6XCB1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_01330</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80520.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061162.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80520">
        <property type="protein sequence ID" value="KPL80520"/>
        <property type="gene ID" value="ADN00_01330"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL80520.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="67" mass="7173" checksum="331621F05DD6EA5B" modified="2016-01-20" version="1">MDELVKLLVKKTGISEEMARKVVPVVLNYLKDRLPAPLSSQLDGVLDDGEIGLDDLAKGLGGLLGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XD82</accession>
    <name>A0A0P6XD82_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_06925</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06925"/>
    <dbReference type="EnsemblBacteria" id="KPL78212">
        <property type="protein sequence ID" value="KPL78212"/>
        <property type="gene ID" value="ADN00_06925"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3201"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="57"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="37"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="91"/>
            <end position="98"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL78212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="313" mass="34512" checksum="F62495537DED0E8A" modified="2016-01-20" version="1">MRNVFMDYAIRVMDVSKKFGKPGEPFWKRLPLLKHVQMPENNGNGHGNGNGHAAAPQEGNGNGKASHDKEIVAVDHVSFDVEKGEIFGVLGPNGGGKSTLIRLMSTLLLPDSGQITVFDIDVVRKPMAVQPLINRVSVEASFFKKLSPLENLLYGARLYGMAGKETRKQVVEILTRLGLEKRSIYNPMEEMSRGMQQKVAIARALLSHPRLLLLDEPTTGLDPRSKREVQAVVRELCQEHGTTILLTTHDMVEAENLCGRVAIMDAGKIVAMDTPQGLKKRVHNENGSETTLEDVFLALTGKQLANKEEEANE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDI3</accession>
    <name>A0A0P6XDI3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Hydrolase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_00240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060948.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00240"/>
    <dbReference type="EnsemblBacteria" id="KPL81014">
        <property type="protein sequence ID" value="KPL81014"/>
        <property type="gene ID" value="ADN00_00240"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3442"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017700">
        <property type="entry name" value="Aminohydrolase_SsnA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03314">
        <property type="entry name" value="Se_ssnA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="1">
        <location>
            <begin position="55"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL81014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="454" mass="50526" checksum="A82DC032A18E93EF" modified="2016-01-20" version="1">MIIKNGKIITWEKENRILDGQAILIQGDMIKKIAPVEDLLREYPGEELVDAKGQYVMPGNICAHTHFYGAYARGMAIPGAAPKDFTEILQKLWFRLDQALDEDSVRASAYVCILDAIKHGTTTLIDHHASPNFIDGSLDVIADVVDETGIRAALCYEVTDRGGEGRMKAGVEENMRFIRKVQSSRPGDGRLSALFGLHAGLTLSEETLDACRRANNVGAGFHIHAAEDAADEYDSLTKSGLRTIDRLQKHGILGRNSIVAHAVHVDIKEIDILAETGTWVTHQPRSNMNNAVGMAQVEGMLRSGVRLGLGNDGMSNDMWEEWKATYFVHKLWHRDSRRMPASLIEQMAVYNNAELATDLFNVGKIGKIEPGAQADLIFVDYHPYTPLTTGNLPWHIVFGFHSSMITTTMVAGKFLMQNRQLIWIDEEKIAREALGFAPDVWKRFVTISQETLEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="31" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDV5</accession>
    <name>A0A0P6XDV5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Probable glycine dehydrogenase (decarboxylating) subunit 2</fullName>
            <ecNumber evidence="4">1.4.4.2</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Glycine cleavage system P-protein subunit 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Glycine decarboxylase subunit 2</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="4">Glycine dehydrogenase (aminomethyl-transferring) subunit 2</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">gcvPB</name>
        <name evidence="6" type="ORF">ADN00_00885</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 4">The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>(R)-N(6)-lipoyl-L-lysyl-[glycine-cleavage complex H protein] + glycine + H(+) = (R)-N(6)-(S(8)-aminomethyldihydrolipoyl)-L-lysyl-[glycine-cleavage complex H protein] + CO2</text>
            <dbReference type="Rhea" id="RHEA:24304"/>
            <dbReference type="Rhea" id="RHEA-COMP:10494"/>
            <dbReference type="Rhea" id="RHEA-COMP:10495"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:57305"/>
            <dbReference type="ChEBI" id="CHEBI:83099"/>
            <dbReference type="ChEBI" id="CHEBI:83143"/>
            <dbReference type="EC" id="1.4.4.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="4">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">The glycine cleavage system is composed of four proteins: P, T, L and H. In this organism, the P 'protein' is a heterodimer of two subunits.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the GcvP family. C-terminal subunit subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.4.4.2" evidence="4"/>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81111.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061062.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00885"/>
    <dbReference type="EnsemblBacteria" id="KPL81111">
        <property type="protein sequence ID" value="KPL81111"/>
        <property type="gene ID" value="ADN00_00885"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3575"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004375">
        <property type="term" value="F:glycine dehydrogenase (decarboxylating) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019464">
        <property type="term" value="P:glycine decarboxylation via glycine cleavage system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00613">
        <property type="entry name" value="GDC-P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00713">
        <property type="entry name" value="GcvPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023012">
        <property type="entry name" value="GcvPB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020581">
        <property type="entry name" value="GDC_P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11773">
        <property type="entry name" value="PTHR11773"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02347">
        <property type="entry name" value="GDC-P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="4">
        <location>
            <position position="265"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003788"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00033655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00713"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL81111.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="487" mass="53005" checksum="00B70C8DC993581C" modified="2016-01-20" version="1">MREPTIYEMSSPGRQGVRYPDPDVPTTPLPEGLVRETLPLPELSELDVVRHYTNISKKNYSIDSGFYPLGSCTMKYNPKVNEEAARLPGFAFTHPLQPTETIQGNLALMFELQQWLAEISGFDAISLQPAAGAQGEFSGVMTIRAYHLHRGDSQRKKMLIPDSAHGTNPATASMCGFETVAIPTDEKGNVDLAALKAACDDTLAGIMLTNPNTLGLFEQGIIEAIEIVHQAGGLVYGDGANLNALLGIARPGDLGIDVMHFNLHKTFSTPHGGGGPGSGPIGVKQHLAPFIPGPVVTVVEEGSQDVPPLFGFTMPEHSIGRVKSFFGNFAMMVRAYVYISMHGPDGLRTISENAVLNANYVRALVNGVYHVPYDRICMHEFVAEGHWNEAPEVSALDIAKRLIDYNFHPPTNYFPLIVHEALMIEPTETESKQTLDRFADALLKIAEEAKNEPALLKDAPHNTPVGRLNEVKAAKDLILCSCDLPYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XES7</accession>
    <name>A0A0P6XES7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05405</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061953.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78687">
        <property type="protein sequence ID" value="KPL78687"/>
        <property type="gene ID" value="ADN00_05405"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="51"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="134" mass="15938" checksum="A25BBEC95E339423" modified="2016-01-20" version="1">MPEKSFERRPILDPIVADLLAGMEQKQAEAQLPRRQREKKIRERQKIRARRDQRATYDLPPFLRQRVKSLAEEHSVPASQLVTLALLQFFEAYDQGQVDLSELKQPSRSPRYDWNLVFPDKWIKPEERKRSKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XF82</accession>
    <name>A0A0P6XF82_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">LuxR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_06485</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78852.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062147.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06485"/>
    <dbReference type="EnsemblBacteria" id="KPL78852">
        <property type="protein sequence ID" value="KPL78852"/>
        <property type="gene ID" value="ADN00_06485"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1801"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="10"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="151"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL78852.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="223" mass="24440" checksum="03AFDFC87CA38837" modified="2016-01-20" version="1">MTGQQQPKITVLLVDDHAIVRDGVRSFLNAQPDLEVIGEAGSGLEAVSLAESLVPDVIVMDLIMPGMDGVEATWRVRKVSPRSQVIVLTSYHEDTHIFPAIKAGALSYLLKDVEPGELADAVRAAARGEAVIHPRVATRVMQELRKDPDREMNPYATLSEREQEVLKLIAEGLSNAAIAERLVLSEKTVKGHVSNILSKLHLADRTQAAVFAWREGIVRREQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XFK2</accession>
    <name>A0A0P6XFK2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Adenine phosphoribosyltransferase</fullName>
            <ecNumber evidence="2">2.4.2.7</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_14775</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.2.7" evidence="2"/>
    <dbReference type="EMBL" id="LGCL01000035">
        <property type="protein sequence ID" value="KPL73600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063800.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000035.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14775"/>
    <dbReference type="EnsemblBacteria" id="KPL73600">
        <property type="protein sequence ID" value="KPL73600"/>
        <property type="gene ID" value="ADN00_14775"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2122"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003999">
        <property type="term" value="F:adenine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRibTrfase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00156">
        <property type="entry name" value="Pribosyltran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="SSF53271"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pribosyltran" evidence="1">
        <location>
            <begin position="45"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL73600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="182" mass="20027" checksum="215A3E6237F18A31" modified="2016-01-20" version="1">MTDRATFPVEIAGVKRDLRLFEVKPGLKIAILNILGDTELVEVAADELLKKLGDGYEAFVTAESKSIPLAYALSAKSKKPYIVLRKEYKPYMGDALQAETLSITTGKPQKLYLDEKDRALIEGKRVVIVDDVISTGSTLEGMRLLMEQAAAEIKAEAAIFTEGDADQWEKIVSLGHLPVFVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XFY7</accession>
    <name>A0A0P6XFY7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">ADP-ribose pyrophosphatase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_04335</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the Nudix hydrolase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061731.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04335"/>
    <dbReference type="EnsemblBacteria" id="KPL79099">
        <property type="protein sequence ID" value="KPL79099"/>
        <property type="gene ID" value="ADN00_04335"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020476">
        <property type="entry name" value="Nudix_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020084">
        <property type="entry name" value="NUDIX_hydrolase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00293">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00502">
        <property type="entry name" value="NUDIXFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="SSF55811"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00893">
        <property type="entry name" value="NUDIX_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="3">
        <location>
            <begin position="67"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003476"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL79099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="206" mass="22777" checksum="654A012EEA668098" modified="2016-01-20" version="1">MANPQWLDWAQRVDAIAQSGLAYTQNPFDIERYQHLQQIAAEMIANQAAEDPQAVLNLLAGEPGYATPKLDIRGVVIQDGKILLVKELSDGGWTLPGGFVDVNESPSTAVEREVCEESGYTVKARRLLALYDRNKHGHPPYLFHVYKIYILCDLTGGEPAVSIETGGAQFFAPHEIPPLSETRTTPEVIQRMFELASRPDGPADFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XG14</accession>
    <name>A0A0P6XG14_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_18135</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL69990.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18135"/>
    <dbReference type="EnsemblBacteria" id="KPL69990">
        <property type="protein sequence ID" value="KPL69990"/>
        <property type="gene ID" value="ADN00_18135"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2930"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004362">
        <property type="term" value="F:glutathione-disulfide reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011767">
        <property type="entry name" value="GLR_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00195">
        <property type="entry name" value="GLUTAREDOXIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="163"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="200"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="231"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="287"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="327"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="368"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="398"/>
            <end position="419"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL69990.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="443" mass="49093" checksum="3903090A92B84035" modified="2016-01-20" version="1">MLPQNDSASKNQAEEQGKAILYLFWGDGCPHCEVAKPFLSELDQSSDLIETRFYEVWNDKANQVKFTEMANAFGFQPQGVPTIFLGTQYWVGFNDQIEAEIKNSVDLCLETGCPDAGVGIFSDVSSGEGQGSQGVQEETLAKKSGESIKIPLIGSVDLSKQSLFVSTLLISFVDGFNPCSVWVLTMLLALTLHTGSRKKVFVIGVVFLTVTAAIYGMFIAGLFTMFTVVSFVTWIQVVVALVALFFALVNIKDYFFYQEGISFTIADKNKPGIFQRIRKLMDNSQSVWGLISGTVVLAAGISLVEFSCTAGFPVLWTNLLVAQNTSIITFLLLLLVYLIIYQLDEMAIFFVAVYTMRASKLEEKHGRILKLIGGVLMFALAVVMLVNPDVMNDLTDSMVVFGIAFGAAILILIVHRWLLPRFGIQFALEPKKDRTRKKNRRSH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XG23</accession>
    <name>A0A0P6XG23_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Glutaredoxin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_18195</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL69999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064472.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18195"/>
    <dbReference type="EnsemblBacteria" id="KPL69999">
        <property type="protein sequence ID" value="KPL69999"/>
        <property type="gene ID" value="ADN00_18195"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2942"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005243">
        <property type="entry name" value="Redox_disulphide_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012336">
        <property type="entry name" value="Thioredoxin-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36450">
        <property type="entry name" value="PTHR36450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13192">
        <property type="entry name" value="Thioredoxin_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037031">
        <property type="entry name" value="Redox_disulphide_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00412">
        <property type="entry name" value="redox_disulf_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin-like_fold" evidence="3">
        <location>
            <begin position="3"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="11"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="1">
        <location>
            <position position="14"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="2">
        <location>
            <begin position="11"/>
            <end position="14"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR037031-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR037031-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL69999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="79" mass="8574" checksum="AB6ED926273958C3" modified="2016-01-20" version="1">MIQIKVLGSGCANCKKLEAIARQAVEDLRLEAEIIKVTDHDEIFKYPILATPGLVVNDKVVSAGRIPSVAEVSEWLKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGG3</accession>
    <name>A0A0P6XGG3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_03735</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061882.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03735"/>
    <dbReference type="EnsemblBacteria" id="KPL79227">
        <property type="protein sequence ID" value="KPL79227"/>
        <property type="gene ID" value="ADN00_03735"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="76" mass="8664" checksum="2F51CAAC78E59383" modified="2016-01-20" version="1">MNRYEIKIKGRLSERWADYFDGLLICPLSDQETLLTGVLPDQAALHGVLCLIQNIGLELISVNRVYTDEGLTHYEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGG6</accession>
    <name>A0A0P6XGG6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">HTH cro/C1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_06190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78809.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06190"/>
    <dbReference type="EnsemblBacteria" id="KPL78809">
        <property type="protein sequence ID" value="KPL78809"/>
        <property type="gene ID" value="ADN00_06190"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013196">
        <property type="entry name" value="HTH_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026881">
        <property type="entry name" value="WYL_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08279">
        <property type="entry name" value="HTH_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13280">
        <property type="entry name" value="WYL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="1">
        <location>
            <begin position="8"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78809.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="314" mass="36076" checksum="04EAC722D0D3A21B" modified="2016-01-20" version="1">MLLAHPEGLTQAEIARRLSVNRSTINRYVADLPAYIYVDDMDGGKWKLDRSADLIHVHLNLHEATAVHLASRLLATCIDRQNPHAAAALRKMAVALERLAPHICQHLAQSADAIDEESRWNDQGFLRSLEVITLAWAAGRKVKLWYRARVNEPVKETVFSPYFIEPGAVGRSTYVIGFSEHHNALRTLKIERIERVEALREAYTIPADFDPRDLLKYAWGIWYTDEEPVEVVLKFSARVAQRLGETRWHCTEQVEPLADGSLLWHAKIAEPQEMMPWIRGWGADVEVLEPERLRENLSDEAKRLMDVYRRSNEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XH77</accession>
    <name>A0A0P6XH77_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DnaB_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_04650</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061790.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04650"/>
    <dbReference type="EnsemblBacteria" id="KPL79148">
        <property type="protein sequence ID" value="KPL79148"/>
        <property type="gene ID" value="ADN00_04650"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034829">
        <property type="entry name" value="DnaD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006343">
        <property type="entry name" value="DnaD_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07261">
        <property type="entry name" value="DnaB_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF158499">
        <property type="entry name" value="SSF158499"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01446">
        <property type="entry name" value="DnaD_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DnaB_2" evidence="2">
        <location>
            <begin position="146"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="219"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF07261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="232" mass="26587" checksum="3BC32FA8AAA2B64D" modified="2016-01-20" version="1">MNVFNGFASSPNQAPTPVPAAFFSELLPQIDHLAELKVTLYTIWFLFQQEGHIRFITEADFLDDELLMSGLAETPQSAQAALREGLERAVARGTLLRAFDSHQEPLYLLNTERGRATIKGLEKGAWSPESIPHAHIHLTADRPNIFRLYEENIGALTPIIANALEDAEKTYPTQWIEDAFRIAVENNVRRWRYIEAILKSWQEEQRDGTNRRDSQENRQRYVQGKYGDIGDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XJK0</accession>
    <name>A0A0P6XJK0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CheX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_17310</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71444.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064305.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17310"/>
    <dbReference type="EnsemblBacteria" id="KPL71444">
        <property type="protein sequence ID" value="KPL71444"/>
        <property type="gene ID" value="ADN00_17310"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028976">
        <property type="entry name" value="CheC-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038756">
        <property type="entry name" value="CheX-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028051">
        <property type="entry name" value="CheX-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39452">
        <property type="entry name" value="PTHR39452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13690">
        <property type="entry name" value="CheX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103039">
        <property type="entry name" value="SSF103039"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CheX" evidence="2">
        <location>
            <begin position="42"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13690"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL71444.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="172" mass="18639" checksum="70A1604E0FC7C8BD" modified="2016-01-20" version="1">MNVKFLNPFLDAAHEVLEAEVQVEMQRGTLTLQKSALTTDDITVLINLVGQVQGVVLYGMSKTTALNFVSQMMGQKFEEFDNLAESGIAELGNVISGRATVKLAEAGYDSTISPPTLITGKSVQISTLDFSRVIVPMSTELGDIIVHLALRESPKNATENYVPLIQDAVRAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XK31</accession>
    <name>A0A0P6XK31_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_13050</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000028">
        <property type="protein sequence ID" value="KPL75310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063463.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000028.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13050"/>
    <dbReference type="EnsemblBacteria" id="KPL75310">
        <property type="protein sequence ID" value="KPL75310"/>
        <property type="gene ID" value="ADN00_13050"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2733"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045725">
        <property type="entry name" value="DUF6079"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19557">
        <property type="entry name" value="DUF6079"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL75310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="1258" mass="144120" checksum="91ADD7F5B6FF523B" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKJ4</accession>
    <name>A0A0P6XKJ4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_11480</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063153.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76568">
        <property type="protein sequence ID" value="KPL76568"/>
        <property type="gene ID" value="ADN00_11480"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025641">
        <property type="entry name" value="DUF4340"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14238">
        <property type="entry name" value="DUF4340"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4340" evidence="1">
        <location>
            <begin position="66"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4340" evidence="1">
        <location>
            <begin position="217"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="322" mass="34239" checksum="E144E3BCE8FD1DE9" modified="2016-01-20" version="1">MNKLQRILVIVLAAQLALTALVFWPRTSTGSGQPLLANFTADQVVKLSVSGAAGEQVSLEKVGDGWVVSGTDGFAAETSRIEAALEKLVEAKRSRQAANTAETHKRLQVAEDAYLRRVALSLADGSQQVVYIGSSPATQAAHARVEGEDAVFLVSNLTANDFSALPSGWIDTLYLDLSAADPQSLAVTNANGTFELNKDESGNWKFSGRQPGEELQATRITSLVTALTQLRMSAPVGTSVKPEYGLDNPQAVAEITALQDGAAQTYTVRVGAQDPASGEYYALVEGKPYVVRITAATAQSLTVLKREDFVRELPTATAPVYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKL6</accession>
    <name>A0A0P6XKL6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_16560</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064153.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72084">
        <property type="protein sequence ID" value="KPL72084"/>
        <property type="gene ID" value="ADN00_16560"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004104">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="5"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA_C" evidence="2">
        <location>
            <begin position="159"/>
            <end position="332"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL72084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="332" mass="37058" checksum="68BD4D3E317C5A1E" modified="2016-01-20" version="1">MKPLRTAILGCGGFANRHAANILTLPEEIELTAFCDIQEANAREFSAKYNQGKGNIYTDHRHMFAKEKLDLAIVCLPPFAHSNEVELAAQNGVHLLMEKPIALSSEHAWRMVEAAEAAGIKTQVGFMFRFGEAIERLQQMAVSREIGTMGLMSARYFCNSLHAPWWRMRDKSGGQLVEQIIHMVDLMRYLLGEPVSVYSRQENLFHQDVPDYTVEDVSATVFGFQSGALGVIYATNGAIPGKWINDYRVVSQKITAEFTNANNAQFHYTAETPVRTETISSEKNIHLAELKNLLNAIRSDGQTRTPLREGARSLDMALAATRSAETHQEVSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKM3</accession>
    <name>A0A0P6XKM3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">ADN00_16670</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="12 13" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="12 13">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064171.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16670"/>
    <dbReference type="EnsemblBacteria" id="KPL72102">
        <property type="protein sequence ID" value="KPL72102"/>
        <property type="gene ID" value="ADN00_16670"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3778"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011096">
        <property type="entry name" value="FTP_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023612">
        <property type="entry name" value="Peptidase_M4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027268">
        <property type="entry name" value="Peptidase_M4/M1_CTD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001570">
        <property type="entry name" value="Peptidase_M4_C_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013856">
        <property type="entry name" value="Peptidase_M4_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07504">
        <property type="entry name" value="FTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01447">
        <property type="entry name" value="Peptidase_M4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02868">
        <property type="entry name" value="Peptidase_M4_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00730">
        <property type="entry name" value="THERMOLYSIN"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133107" evidence="8">
        <location>
            <begin position="24"/>
            <end position="1147"/>
        </location>
    </feature>
    <feature type="domain" description="FTP" evidence="11">
        <location>
            <begin position="103"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M4" evidence="9">
        <location>
            <begin position="249"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M4_C" evidence="10">
        <location>
            <begin position="357"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="active site" evidence="7">
        <location>
            <position position="347"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="437"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009388"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR623612-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF02868"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF07504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KPL72102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="1147" mass="126725" checksum="75B901065037E569" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XL36</accession>
    <name>A0A0P6XL36_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH luxR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_09975</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76916.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062854.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76916">
        <property type="protein sequence ID" value="KPL76916"/>
        <property type="gene ID" value="ADN00_09975"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041617">
        <property type="entry name" value="TPR_MalT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17874">
        <property type="entry name" value="TPR_MalT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="789"/>
            <end position="854"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL76916.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="856" mass="95044" checksum="37FB1B43324AD1B9" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XL88</accession>
    <name>A0A0P6XL88_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PKD domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_00425</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81040.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL81040">
        <property type="protein sequence ID" value="KPL81040"/>
        <property type="gene ID" value="ADN00_00425"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="Glycoside_hydrolase_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000601">
        <property type="entry name" value="PKD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035986">
        <property type="entry name" value="PKD_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49299">
        <property type="entry name" value="SSF49299"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="SSF51445"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50093">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PKD" evidence="1">
        <location>
            <begin position="70"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL81040.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="938" mass="106337" checksum="2EB12A1F03F1F2CC" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XLE6</accession>
    <name>A0A0P6XLE6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_00900</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061065.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL81113">
        <property type="protein sequence ID" value="KPL81113"/>
        <property type="gene ID" value="ADN00_00900"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001769">
        <property type="entry name" value="Gingipain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01364">
        <property type="entry name" value="Peptidase_C25"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_C25" evidence="2">
        <location>
            <begin position="412"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_C25" evidence="2">
        <location>
            <begin position="638"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="325"/>
            <end position="357"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL81113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="918" mass="102211" checksum="980CE453CD7ABAC8" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XMP5</accession>
    <name>A0A0P6XMP5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Histidine kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_00940</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061073.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00940"/>
    <dbReference type="EnsemblBacteria" id="KPL81119">
        <property type="protein sequence ID" value="KPL81119"/>
        <property type="gene ID" value="ADN00_00940"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="SSF47384"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Histidine kinase" evidence="2">
        <location>
            <begin position="156"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL81119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="415" mass="46771" checksum="EEBEBB40ECA1B439" modified="2016-01-20" version="1">MSIQESLQSIQAEWIHQILIQLSPEDPTNEDLIRLVSHFFAQFSQAVINCQPAFLEPEIENFSSALPSTDLEGKSNQVSQFLKIFVDTFYHTGRETLSAQSFLELLDAAFPVTTRAFEISSDLETKSVRQRSDAEIETLKQQMEKIDRSKSDFIAVAAHELKTPLTLIEGYSMMLKEIIIPDGNDYQASLIDGIRNGTRRLKMIIDDMVDVTLIENNLLKLNFQPVWLNQLFAHLQAELQPALDQRFIRLEIDPFPGFSEMTFGAPDRLEQVFRNILNNAIKFTPDHGWIYIEGRQLPGFIEVIVRDTGIGINPEDQPLIFNKFSRIGNVALHSSGKTKFKGGGPGLGLYIAKGIVESHGGAIWVESEKCDEDKLPGSAFHVILPTRSALSDDKMTHLFSNGPKTYHQEVPKQLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XMW2</accession>
    <name>A0A0P6XMW2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ABC transmembrane type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_11440</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76563.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063147.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11440"/>
    <dbReference type="EnsemblBacteria" id="KPL76563">
        <property type="protein sequence ID" value="KPL76563"/>
        <property type="gene ID" value="ADN00_11440"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="16"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="63"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="151"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="194"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="255"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="64"/>
            <end position="271"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL76563.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="283" mass="31401" checksum="EC8C285554F1E0EA" modified="2016-01-20" version="1">MKKNGHTLVLMSPSGLWLIAFFLIPLAIMAVYSFGSGSFDLIGQSFSLDTYVKFFNTPSFLNLLWRSTVIAFYTALLSVLMAYPIAYFLAFQAGSWRTSLLTIIIIPSWISYLLRILAIKLILGSSGLLNSLLMGLGLVQESVPLLMYSRSAVMITLVYTWIPFAALPIFSALERIGKPLLEAASDLGSPPWKAFLRVTLPLSLPGVWASFFFVFIPTLGEWVTPALMGGPQGIMYGNLIQDQFVRALNWPMGSVMSMVMTLLVIVFLMILTRFIKLSELLEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XNL9</accession>
    <name>A0A0P6XNL9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_09735</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76873">
        <property type="protein sequence ID" value="KPL76873"/>
        <property type="gene ID" value="ADN00_09735"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="68" mass="7425" checksum="25A1DDEDA7D1A2BE" modified="2016-01-20" version="1">MKVIHQDQVRESVQVFEAFSKLGKDLHRARRATAAGGLDGHLLEIGEGAVNYADGVIGDFHSYPLAMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XNT4</accession>
    <name>A0A0P6XNT4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_14360</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000034">
        <property type="protein sequence ID" value="KPL73748.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063719.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000034.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14360"/>
    <dbReference type="EnsemblBacteria" id="KPL73748">
        <property type="protein sequence ID" value="KPL73748"/>
        <property type="gene ID" value="ADN00_14360"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1391"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="59"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="135"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="166"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="189"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="220"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="253"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL73748.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="290" mass="30936" checksum="45321DD8724BFAE4" modified="2016-01-20" version="1">MIWQQIVNGISVGSIYALMATGYALIYSLLGFSNWAHGDIAMVGAYLGFFFVASLHLPWWAALILALLGAGLLSVISERVAYRKIRKNNSPTMFLMIAAMGLSVALQNFVLVTIGSKFKTYPQILPVKAIEIGGVYVGLLDLISFLGAVIVIIILYYLIERTKFGLAVKAAAANMQVASLLGINVDKYISLVFLLAGSLAGLSGVFLGMKYTVYPQLGNFALKAFIASVFGGLGSVPGAIVGALFIGLMEVFVAGYVSAGLRDLFTFTLLVAVLVIRPTGLFGKDIQDKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XPS9</accession>
    <name>A0A0P6XPS9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_09005</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77267.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062665.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77267">
        <property type="protein sequence ID" value="KPL77267"/>
        <property type="gene ID" value="ADN00_09005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="SSF81653"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="SSF81660"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="121"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="145"/>
            <end position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL77267.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="288" mass="33165" checksum="364CE4F96CB73955" modified="2016-01-20" version="1">MNANLVTIEIDGKLTNIDEKDLRISDLVIIQTGDIVPADLRLIEFRGLEIDEFEITGELLPVEKKIAKDDVIAYHGSRVIRGYGKGVVLSTGEQTEYGKVLSQEGQQNQPYTFRIIDKENLWTIILFLPVFVLLFVQSYDLTLLIIFLFFSFVLNLLQNDNLCRYLIISNESKRLKRAHVQIRDIRALEHMGDINLVCFDKTGVLTTRQMDIKKVYFPDLIIETENGTKNIEESVAQLVYKACALCNDVLFFQKTILANPIDLALIRFAQKNRIDVNELLLQYKRIYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XPW7</accession>
    <name>A0A0P6XPW7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">D-mannonate oxidoreductase</fullName>
            <ecNumber evidence="2">1.1.1.131</ecNumber>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09225</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.131" evidence="2"/>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062703.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09225"/>
    <dbReference type="EnsemblBacteria" id="KPL77303">
        <property type="protein sequence ID" value="KPL77303"/>
        <property type="gene ID" value="ADN00_09225"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4079"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050090">
        <property type="term" value="F:mannuronate reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020904">
        <property type="entry name" value="Sc_DH/Rdtase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00061">
        <property type="entry name" value="ADH_SHORT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="245"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="277" mass="29115" checksum="9F0417845536CB66" modified="2016-01-20" version="1">MGKKDLIMTPDTFDLQNQVAVVTGGAGVLCAAMCRALARAGAKVAVLDLREEAAQALAAEIGNGAVGVGCNVLEKDGVESAARRVVEVYGRVDILINGAGGNKPQATTSPELSFFDLPPDALSWVFQLNLLGAILPSQAFGKIMAAQRQGVILNISSMNAFRPLTRIPAYSAAKAGVSNFTQWLAVHMAQEYSPAIRVNAIAPGFFLTEQNRYLLMDRDSGELTPRGKTILAHTPQGRFGSPEDLLGAVLWLVSPASAFVTGVVIPIDGGFSAFSGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XPX3</accession>
    <name>A0A0P6XPX3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Phosphoribosylamine--glycine ligase</fullName>
            <ecNumber evidence="2">6.3.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_05880</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Purine metabolism; IMP biosynthesis via de novo pathway; N(1)-(5-phospho-D-ribosyl)glycinamide from 5-phospho-alpha-D-ribose 1-diphosphate: step 2/2.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.4.13" evidence="2"/>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78763.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062038.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05880"/>
    <dbReference type="EnsemblBacteria" id="KPL78763">
        <property type="protein sequence ID" value="KPL78763"/>
        <property type="gene ID" value="ADN00_05880"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1652"/>
    <dbReference type="UniPathway" id="UPA00074">
        <property type="reaction ID" value="UER00125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004637">
        <property type="term" value="F:phosphoribosylamine-glycine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006189">
        <property type="term" value="P:'de novo' IMP biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009113">
        <property type="term" value="P:purine nucleobase biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.600.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011761">
        <property type="entry name" value="ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016185">
        <property type="entry name" value="PreATP-grasp_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020561">
        <property type="entry name" value="PRibGlycinamid_synth_ATP-grasp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000115">
        <property type="entry name" value="PRibGlycinamide_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020560">
        <property type="entry name" value="PRibGlycinamide_synth_C-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037123">
        <property type="entry name" value="PRibGlycinamide_synth_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020559">
        <property type="entry name" value="PRibGlycinamide_synth_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020562">
        <property type="entry name" value="PRibGlycinamide_synth_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011054">
        <property type="entry name" value="Rudment_hybrid_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43472">
        <property type="entry name" value="PTHR43472"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01071">
        <property type="entry name" value="GARS_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02843">
        <property type="entry name" value="GARS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02844">
        <property type="entry name" value="GARS_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01210">
        <property type="entry name" value="GARS_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51246">
        <property type="entry name" value="SSF51246"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52440">
        <property type="entry name" value="SSF52440"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00877">
        <property type="entry name" value="purD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50975">
        <property type="entry name" value="ATP_GRASP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00184">
        <property type="entry name" value="GARS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0436">Ligase</keyword>
    <keyword evidence="4 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-0658">Purine biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATP-grasp" evidence="8">
        <location>
            <begin position="111"/>
            <end position="318"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013255"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50975"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL78763.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="444" mass="48742" checksum="882FEB1615F9DB01" modified="2016-01-20" version="1">MNIGLIGSGGREHAIAAALTRNPQRDHLIVYGNSNNVGIERLAQVYHNGSLTDIQAIVSFFTKNPVDYVVIGPELPLTHGAADAIRAAHIPAVGPNQFQAQLEGSKTFMRDLMQKHIGWGSLRWHKAHTCEEARLFIEEVGQAVIKPIGLTGGKGVQVMGEHLHSTEEALVLVDQILKTDGVVLLEERLVGEEFSRIALVSDGNIVPMPIAQDFKYAYEGDKGGMTGGMGSYTMIDGRMPFLADSDIQQADRLMAEVVTALEKVSGAPYRGFLYGQFMATRDGVTIIEFNVRLGDPEAINVMALWDCDTAEILHNAALGTLRPEELTFEKQASLCKYLVPAGYPEKTQKDLVFNLDETKIFNAGFDIRYASVEKAGSEFRTLGSRTLAIIGKGENLAALSEEMEHLLQAIEPPVLRHRKDIGTQDTLNRKTAHLQQLRSKTDHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XPZ1</accession>
    <name>A0A0P6XPZ1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_06065</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78790.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062073.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78790">
        <property type="protein sequence ID" value="KPL78790"/>
        <property type="gene ID" value="ADN00_06065"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78790.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="79" mass="9060" checksum="1BFBE83139845320" modified="2016-01-20" version="1">MNTVNPKYYEIEILEPIDPCWAEWFSGLEIATQAENNIKKTLLRGTLPDQASLYGVLGRIQSLNLTLLSVRWIVNPEDR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XR15</accession>
    <name>A0A0P6XR15_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_16085</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FAD-dependent glycerol-3-phosphate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064062.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16085"/>
    <dbReference type="EnsemblBacteria" id="KPL72012">
        <property type="protein sequence ID" value="KPL72012"/>
        <property type="gene ID" value="ADN00_16085"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3652"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009331">
        <property type="term" value="C:glycerol-3-phosphate dehydrogenase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004368">
        <property type="term" value="F:glycerol-3-phosphate dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006072">
        <property type="term" value="P:glycerol-3-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.870">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031656">
        <property type="entry name" value="DAO_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038299">
        <property type="entry name" value="DAO_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006076">
        <property type="entry name" value="FAD-dep_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000447">
        <property type="entry name" value="G3P_DH_FAD-dep"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11985">
        <property type="entry name" value="PTHR11985"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01266">
        <property type="entry name" value="DAO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16901">
        <property type="entry name" value="DAO_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01001">
        <property type="entry name" value="FADG3PDH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="SSF51905"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0274">FAD</keyword>
    <keyword evidence="3" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DAO" evidence="6">
        <location>
            <begin position="19"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="domain" description="DAO_C" evidence="7">
        <location>
            <begin position="413"/>
            <end position="508"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL72012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="530" mass="59722" checksum="21823CFA372548D6" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XRI9</accession>
    <name>A0A0P6XRI9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA_edit domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_02940</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PRORSD1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000013">
        <property type="protein sequence ID" value="KPL79412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02940"/>
    <dbReference type="EnsemblBacteria" id="KPL79412">
        <property type="protein sequence ID" value="KPL79412"/>
        <property type="gene ID" value="ADN00_02940"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002161">
        <property type="term" value="F:aminoacyl-tRNA editing activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.960.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040285">
        <property type="entry name" value="ProX/PRXD1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036754">
        <property type="entry name" value="YbaK/aa-tRNA-synt-asso_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007214">
        <property type="entry name" value="YbaK/aa-tRNA-synth-assoc-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31423">
        <property type="entry name" value="PTHR31423"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04073">
        <property type="entry name" value="tRNA_edit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55826">
        <property type="entry name" value="SSF55826"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA_edit" evidence="2">
        <location>
            <begin position="17"/>
            <end position="143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="171" mass="18777" checksum="6E7DD1B785914002" modified="2016-01-20" version="1">MIAFLREHAIPYQRVEHPPVYTSAESGFYLQNAPGEEGKNLFLTDKKGRRTFLVLSLERKRVDLKALGDLLGAPKLKFASEERLAERLGVTPGAVDALAVINDVESKVELVIDADLWRNEAIRSHPLVNTATLILARADLERFFALTGHTPLIVPLPELSAGEPSAPEADA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XS18</accession>
    <name>A0A0P6XS18_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 6">Shikimate dehydrogenase (NADP(+))</fullName>
            <shortName evidence="6">SDH</shortName>
            <ecNumber evidence="3 6">1.1.1.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">aroE</name>
        <name evidence="10" type="ORF">ADN00_02470</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Involved in the biosynthesis of the chorismate, which leads to the biosynthesis of aromatic amino acids. Catalyzes the reversible NADPH linked reduction of 3-dehydroshikimate (DHSA) to yield shikimate (SA).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>NADP(+) + shikimate = 3-dehydroshikimate + H(+) + NADPH</text>
            <dbReference type="Rhea" id="RHEA:17737"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16630"/>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.25"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 6">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 4/7.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the shikimate dehydrogenase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.25" evidence="3 6"/>
    <dbReference type="EMBL" id="LGCL01000011">
        <property type="protein sequence ID" value="KPL79567.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061376.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000011.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02470"/>
    <dbReference type="EnsemblBacteria" id="KPL79567">
        <property type="protein sequence ID" value="KPL79567"/>
        <property type="gene ID" value="ADN00_02470"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2804"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00087"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004764">
        <property type="term" value="F:shikimate 3-dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:cellular amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019632">
        <property type="term" value="P:shikimate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00222">
        <property type="entry name" value="Shikimate_DH_AroE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046346">
        <property type="entry name" value="Aminiacid_DH-like_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041121">
        <property type="entry name" value="SDH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011342">
        <property type="entry name" value="Shikimate_DH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013708">
        <property type="entry name" value="Shikimate_DH-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022893">
        <property type="entry name" value="Shikimate_DH_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006151">
        <property type="entry name" value="Shikm_DH/Glu-tRNA_Rdtase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21089">
        <property type="entry name" value="PTHR21089"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18317">
        <property type="entry name" value="SDH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01488">
        <property type="entry name" value="Shikimate_DH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08501">
        <property type="entry name" value="Shikimate_dh_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53223">
        <property type="entry name" value="SSF53223"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00507">
        <property type="entry name" value="aroE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="5 6" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="6" id="KW-0521">NADP</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Shikimate_dh_N" evidence="8">
        <location>
            <begin position="10"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="Shikimate_DH" evidence="7">
        <location>
            <begin position="123"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="domain" description="SDH_C" evidence="9">
        <location>
            <begin position="254"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Shikimate binding" evidence="6">
        <location>
            <begin position="18"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="69"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="65"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="90"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="110"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <begin position="132"/>
            <end position="136"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="261"/>
        </location>
        <ligand>
            <name>shikimate</name>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004871"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF08501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF18317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL79567.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="292" mass="31058" checksum="751081E6A7C7BF14" modified="2016-01-20" version="1">MDGKTTLTGLLGWPVEHSLSPALHNAAFAALGLNWAYLPLPTPPEHLPDVLRGLARCGFRGLNVTIPHKQAVLPLLDALSPTAAALGAVNTISIQTAEDGTPCLRGDNTDVEGFLHPLRAQSHTPRSAVVVGAGGAARAVIYGLLQLGTRKIYLLNRNPAHALQLAQSLQPLAEDGAGIIPLPFGSSTLIEACQTAELLVNTTPLGMWPHTQGCIWPEVTPIPARLTVYDLVYNPYQTRLLQIAEQSGARAIGGLEMLIHQAAAAFQIWTGQPAPIETMLQACPPSWRNPSC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XTM1</accession>
    <name>A0A0P6XTM1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH tetR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_11395</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76555.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063139.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76555">
        <property type="protein sequence ID" value="KPL76555"/>
        <property type="gene ID" value="ADN00_11395"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009057">
        <property type="entry name" value="Homeobox-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001647">
        <property type="entry name" value="HTH_TetR"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00440">
        <property type="entry name" value="TetR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00455">
        <property type="entry name" value="HTHTETR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46689">
        <property type="entry name" value="SSF46689"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50977">
        <property type="entry name" value="HTH_TETR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH tetR-type" evidence="2">
        <location>
            <begin position="11"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="H-T-H motif" evidence="1">
        <location>
            <begin position="34"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50977"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL76555.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="200" mass="23532" checksum="122E975E9A83FA84" modified="2016-01-20" version="1">MPRGFSDEEKTRIRARLLEKGRGLFEQYGLKKTNVEDLTRAAGISKGAFYHFYESKEELFFEILDRVEEEFHQRVFTAAVDETLPAREGLIRFLRTVFEQLAHYPLLYSVGKDEYESLLRKLPREKAEAHVRGDALALEQVMSRFRQTGRLREIDPQLFANLGVSLYLLWMHRDDMVFSRFEETLDAWIEMLAGYLVLDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XU45</accession>
    <name>A0A0P6XU45_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09745</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76875.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062810.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76875">
        <property type="protein sequence ID" value="KPL76875"/>
        <property type="gene ID" value="ADN00_09745"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76875.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="147" mass="16880" checksum="41AAA0CA6C44AA55" modified="2016-01-20" version="1">MEQPIPLSDIISIIALLVSFFALFISWRQFLRDQSHLILRIEIQDNIHTGPMFIVYAVNKGRRPITIVRADARVSSGKEYPVFDTCTTLNETETLEFNVPISGFFKSISSGYYITAFELVDSTGKRHITKTRRLRRQVASVLDRKVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XU95</accession>
    <name>A0A0P6XU95_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_10125</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76939.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062884.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76939">
        <property type="protein sequence ID" value="KPL76939"/>
        <property type="gene ID" value="ADN00_10125"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76939.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="105" mass="12108" checksum="4F8D98C7531376E0" modified="2016-01-20" version="1">MTTLPINECFEPPDELDGAKVLLWAYNPEKPFFMMLFEDGSNYKPIHGFAICRYGGEELFYKFSCNSEWEVENDSDHASIEEAIHAAHHLSKEPIVWNQKLPATE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUG4</accession>
    <name>A0A0P6XUG4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glyco_hydro_15 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10730</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062994.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10730"/>
    <dbReference type="EnsemblBacteria" id="KPL77030">
        <property type="protein sequence ID" value="KPL77030"/>
        <property type="gene ID" value="ADN00_10730"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008928">
        <property type="entry name" value="6-hairpin_glycosidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012341">
        <property type="entry name" value="6hp_glycosidase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011613">
        <property type="entry name" value="GH15-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00723">
        <property type="entry name" value="Glyco_hydro_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48208">
        <property type="entry name" value="SSF48208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_hydro_15" evidence="1">
        <location>
            <begin position="5"/>
            <end position="279"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="361" mass="40519" checksum="1D88B987D9C6D7D7" modified="2016-01-20" version="1">MTPSLLQRSIEIILANQHPSGAYLASPNFPTYHYSWFRDGTYIAYAMDLAGETESARQFHQWVAQTILRHEGTAQRAAEKARAGQPLSPQDVLHTRYTVTGEAAAEDWPNFQSDGFGAWLWGLSQHLEISSAPLSGECERAARLIADYLAALWQHPCYDCWEEFGDRVHAYTLAAIYGGLEACTRMGLADYRSVTAAIREKIDTQLFNGAYFSKFIGTPLVDSSLLGLAVPYGVVDPRDARMRATVAKIEQDLLHAGGIQRYAEDTYYGGGEWVLLTAWWGWYWSLAGDPEKARQAKAWIEAQANPLGWLPEQVPLHVNAPEHYQPWVQRWGPIANPLLWSQAMYIILDHHLRAGSRQPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUN7</accession>
    <name>A0A0P6XUN7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_06225</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78885.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06225"/>
    <dbReference type="EnsemblBacteria" id="KPL78885">
        <property type="protein sequence ID" value="KPL78885"/>
        <property type="gene ID" value="ADN00_06225"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="5"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="259"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="38"/>
            <end position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL78885.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="510" mass="56822" checksum="A2D9CB6E66C7717A" modified="2016-01-20" version="1">MENLIEMQNIVKVFPPSLVALDNVTVEFRKGEIHAIVGENGAGKSTLMKILYGMEERGAGEILHHGKPIHFKQPGDAIASGIGMVHQEILLIPEYTVWENVVLGVEPRNVWGRLDAAKAQAQVAQKIQEFQLNLNPTALVEDISVAARQKVEILKLLFRNVSVLILDEPTAVLTPQEIPQLFSELRRLKDNGHTILFISHHLDEVIELSDRTTVLRKGQKIATVDTASTSKRELAQMMVGREVIFSSIANQGQPGEVVFSVENLNHAHHNGHQFLKDINFAVRAGEIVGVAGVEGNGQLELVNAIMGLLEHTSGKISVNGKEITHLPILERRKLISFVSQDRGKMGASITASIRENSMMTHHRLNPRLSRWKGRLLVGEATRQFTREIEKQFSVSMGDMDNAFRSLSGGNQQKVILGRELLLNSPFLLLDQPTRGLDVGSIEYVHQQILNMRDNQRAILLISADLEELFRLSDRILVLHRGRIVADLAAEQTSLEEVGILMLEGKEKDHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="27" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUZ6</accession>
    <name>A0A0P6XUZ6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH luxR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_09070</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062678.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77277">
        <property type="protein sequence ID" value="KPL77277"/>
        <property type="gene ID" value="ADN00_09070"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4048"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041617">
        <property type="entry name" value="TPR_MalT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17874">
        <property type="entry name" value="TPR_MalT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="850"/>
            <end position="915"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="917" mass="101822" checksum="148330D5AEC8FE5F" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XVA6</accession>
    <name>A0A0P6XVA6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 4">Triosephosphate isomerase</fullName>
            <shortName evidence="3">TIM</shortName>
            <shortName evidence="3">TPI</shortName>
            <ecNumber evidence="3 4">5.3.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="3">Triose-phosphate isomerase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="3 5" type="primary">tpiA</name>
        <name evidence="5" type="ORF">ADN00_04785</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="3">Involved in the gluconeogenesis. Catalyzes stereospecifically the conversion of dihydroxyacetone phosphate (DHAP) to D-glyceraldehyde-3-phosphate (G3P).</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3 4">
            <text>D-glyceraldehyde 3-phosphate = dihydroxyacetone phosphate</text>
            <dbReference type="Rhea" id="RHEA:18585"/>
            <dbReference type="ChEBI" id="CHEBI:57642"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="5.3.1.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Carbohydrate biosynthesis; gluconeogenesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3 4">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate from glycerone phosphate: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3 4">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 4">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 4">Belongs to the triosephosphate isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.1" evidence="3 4"/>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79168.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061815.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04785"/>
    <dbReference type="EnsemblBacteria" id="KPL79168">
        <property type="protein sequence ID" value="KPL79168"/>
        <property type="gene ID" value="ADN00_04785"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.321"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00189"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00138"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004807">
        <property type="term" value="F:triose-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00311">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00147_B">
        <property type="entry name" value="TIM_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035990">
        <property type="entry name" value="TIM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022896">
        <property type="entry name" value="TrioseP_Isoase_bac/euk"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000652">
        <property type="entry name" value="Triosephosphate_isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020861">
        <property type="entry name" value="Triosephosphate_isomerase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21139">
        <property type="entry name" value="PTHR21139"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00121">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51351">
        <property type="entry name" value="SSF51351"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00419">
        <property type="entry name" value="tim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00171">
        <property type="entry name" value="TIM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51440">
        <property type="entry name" value="TIM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="1 3 4" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="3 4" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="2 3 4" id="KW-0413">Isomerase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="9"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="region of interest" description="Substrate binding" evidence="3">
        <location>
            <begin position="234"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="active site" description="Electrophile" evidence="3">
        <location>
            <position position="94"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="166"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="172"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <position position="213"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL79168.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="252" mass="26153" checksum="795648438BC5EF51" modified="2016-01-20" version="1">MRKPFVAGNWKMNKTAAEAATLVGAMLPELDKIDAVEIVLCPPATAVPAVSGLVKGSKVGVGTQNLHWEESGAFTGELSPAMVAEFCGYVIIGHSERRAYFAETDETVNKKVKAALAHGLTPIMCVGETLEENEAGRTNEVVVGQVKADMAGLSAEEAAKVVVAYEPIWAIGTGKAASGDLANKVIFETIRVPLKEMFGSAAAEAVRVLYGGSVKGSNAAEFFGQAEIDGALVGGASLKAEDFLAIVKAAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XWU6</accession>
    <name>A0A0P6XWU6_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Histidine kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_00355</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060968.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00355"/>
    <dbReference type="EnsemblBacteria" id="KPL81030">
        <property type="protein sequence ID" value="KPL81030"/>
        <property type="gene ID" value="ADN00_00355"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Histidine kinase" evidence="1">
        <location>
            <begin position="484"/>
            <end position="675"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL81030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="675" mass="76174" checksum="FB7C53727E10569A" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y1Q1</accession>
    <name>A0A0P6Y1Q1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_12765</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75513.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063406.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000027.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12765"/>
    <dbReference type="EnsemblBacteria" id="KPL75513">
        <property type="protein sequence ID" value="KPL75513"/>
        <property type="gene ID" value="ADN00_12765"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="SSF54106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LysM" evidence="2">
        <location>
            <begin position="109"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="60"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL75513.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="168" mass="18849" checksum="0044790D3276DCAA" modified="2016-01-20" version="1">MPEDKKKNIFEKAVDALSSRDEKEAKAEAEKAAEEARQVAAKAAKEKAVAEIQANQAKRQAEEAQKKMEEMKKQQEEAKAKEAIEARKEQFAEQLAAMKAAKPEVKVIAEHTVKAGETLSHIALKYYGSAVRDNWMHIYEFNKDVIGDNPNFVREGVTLKIPELPAEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y1Q8</accession>
    <name>A0A0P6Y1Q8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_12835</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75523.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063418.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000027.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL75523">
        <property type="protein sequence ID" value="KPL75523"/>
        <property type="gene ID" value="ADN00_12835"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL75523.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="62" mass="6998" checksum="B24C99BB88EB6F8E" modified="2016-01-20" version="1">MGEPKNFSVEDPATQEKIRQFCYELALVLRRITGRIVSDAELCLPEDLGISEQAKTTDTQNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y4L4</accession>
    <name>A0A0P6Y4L4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Excinuclease ABC subunit C</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01850</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000007">
        <property type="protein sequence ID" value="KPL80038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061261.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000007.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01850"/>
    <dbReference type="EnsemblBacteria" id="KPL80038">
        <property type="protein sequence ID" value="KPL80038"/>
        <property type="gene ID" value="ADN00_01850"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000305">
        <property type="entry name" value="GIY-YIG_endonuc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035901">
        <property type="entry name" value="GIY-YIG_endonuc_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01541">
        <property type="entry name" value="GIY-YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82771">
        <property type="entry name" value="SSF82771"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50164">
        <property type="entry name" value="GIY_YIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GIY-YIG" evidence="1">
        <location>
            <begin position="2"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="87" mass="10096" checksum="15803901FB150E66" modified="2016-01-20" version="1">MNGYFCYIVQCADGSFYTGWTTDPERRVRQHNRGQGARYTRLHGPVRLVYLESLPDRSAAMKREVSIKRLTRAQKQALASTYNQILE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y5W8</accession>
    <name>A0A0P6Y5W8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Transcription elongation factor GreA</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="4">Transcript cleavage factor GreA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="4" type="primary">greA</name>
        <name evidence="8" type="ORF">ADN00_10425</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5">Necessary for efficient RNA polymerase transcription elongation past template-encoded arresting sites. The arresting sites in DNA have the property of trapping a certain fraction of elongating RNA polymerases that pass through, resulting in locked ternary complexes. Cleavage of the nascent transcript by cleavage factors such as GreA or GreB allows the resumption of elongation from the new 3'terminus. GreA releases sequences of 2 to 3 nucleotides.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4 5">Belongs to the GreA/GreB family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062939.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10425"/>
    <dbReference type="EnsemblBacteria" id="KPL76985">
        <property type="protein sequence ID" value="KPL76985"/>
        <property type="gene ID" value="ADN00_10425"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2552"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070063">
        <property type="term" value="F:RNA polymerase binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032784">
        <property type="term" value="P:regulation of DNA-templated transcription, elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.180">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00105">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036953">
        <property type="entry name" value="GreA/GreB_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006359">
        <property type="entry name" value="Tscrpt_elong_fac_GreA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028624">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001437">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023459">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022691">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036805">
        <property type="entry name" value="Tscrpt_elong_fac_GreA/B_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30437">
        <property type="entry name" value="PTHR30437"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01272">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03449">
        <property type="entry name" value="GreA_GreB_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006092">
        <property type="entry name" value="GreA_GreB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46557">
        <property type="entry name" value="SSF46557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01462">
        <property type="entry name" value="greA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 4 5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="8" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="8" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0804">Transcription</keyword>
    <keyword evidence="1 4 5" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="GreA_GreB_N" evidence="7">
        <location>
            <begin position="4"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="domain" description="GreA_GreB" evidence="6">
        <location>
            <begin position="79"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00105"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU000556"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF01272"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF03449"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL76985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="152" mass="17046" checksum="D336428C35A4B868" modified="2016-01-20" version="1">MTTYLTQEGYQKFQEELHDLIYRRRDEVAAILRETVGNGEDENPEYEMARAEQAFIEGRIRELEMLLSSAKIIEESAMPSSVVQIGSKVTIQEEGYDPETYMIVGSAEANPKEGRISNESPIGKAIMSRAAGDEVMVHTPTGNYTVKILQVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y9G4</accession>
    <name>A0A0P6Y9G4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Cobalt ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_06710</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000018">
        <property type="protein sequence ID" value="KPL78412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062210.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000018.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06710"/>
    <dbReference type="EnsemblBacteria" id="KPL78412">
        <property type="protein sequence ID" value="KPL78412"/>
        <property type="gene ID" value="ADN00_06710"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2253"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03225">
        <property type="entry name" value="ABC_cobalt_CbiO_domain1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015856">
        <property type="entry name" value="ABC_transpr_CbiO/EcfA_su"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3 5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="11"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="44"/>
            <end position="51"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL78412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="239" mass="26056" checksum="B2DF0C1DDBFC6977" modified="2016-01-20" version="1">MEIDSTFSHVIEITRLNYTYPDGRQALHDLSLQVSPGEKVALIGANGAGKSTLLLHLNGILNGDGALRVAGMELTQANLPRVRALVGMVFQSPDDQLFSPTVFEDVAYGPVYQGLPPAEIEQRVRTALEAVGMDDFARRSSYHLSIGEKKRIALATVLSMQPQVLALDEPSAGLDPRARRELIHLLKEMPQTMLVATHDLALARDLLPRTVLLHKGRVVADGPTEKLLDDETLLLANGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YA99</accession>
    <name>A0A0P6YA99_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05845</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BtpA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78759.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062032.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78759">
        <property type="protein sequence ID" value="KPL78759"/>
        <property type="gene ID" value="ADN00_05845"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005137">
        <property type="entry name" value="BtpA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21381">
        <property type="entry name" value="PTHR21381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03437">
        <property type="entry name" value="BtpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005956">
        <property type="entry name" value="BtpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00259">
        <property type="entry name" value="thylakoid_BtpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78759.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="266" mass="28614" checksum="35E961A8CD93065C" modified="2016-01-20" version="1">MAALSEIFPKKKFIIGMIHLPALPGTPNGKNARFSELSKYALQELDALQSGGVDGVIVENFWDLPYYPERVDTVTIAAEAALAGLIVEHASIPVGINVLYNDFHAELAIARAVNASFIRAEVFIDPAISETGLIPASSAFMIRERSALNADQVAIFADVHGKNTQVIWQREITESAVDAETRGLADAIIVTGAGTGKSASLEDLRSVKEKIHIPLLAGSGVKPSTLLDIFSVCDGVIVGSYFKEAGNIHAKTDVERVRELTRLNTF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YAG8</accession>
    <name>A0A0P6YAG8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 5">Glucose-1-phosphate thymidylyltransferase</fullName>
            <ecNumber evidence="4 5">2.7.7.24</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_06535</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the formation of dTDP-glucose, from dTTP and glucose 1-phosphate, as well as its pyrophosphorolysis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>alpha-D-glucose 1-phosphate + dTTP + H(+) = diphosphate + dTDP-alpha-D-glucose</text>
            <dbReference type="Rhea" id="RHEA:15225"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:37568"/>
            <dbReference type="ChEBI" id="CHEBI:57477"/>
            <dbReference type="ChEBI" id="CHEBI:58601"/>
            <dbReference type="EC" id="2.7.7.24"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the glucose-1-phosphate thymidylyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.7.24" evidence="4 5"/>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78860.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062157.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06535"/>
    <dbReference type="EnsemblBacteria" id="KPL78860">
        <property type="protein sequence ID" value="KPL78860"/>
        <property type="gene ID" value="ADN00_06535"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1811"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008879">
        <property type="term" value="F:glucose-1-phosphate thymidylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045226">
        <property type="term" value="P:extracellular polysaccharide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02538">
        <property type="entry name" value="G1P_TT_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005907">
        <property type="entry name" value="G1P_thy_trans_s"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43532">
        <property type="entry name" value="PTHR43532"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00483">
        <property type="entry name" value="NTP_transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="SSF53448"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01207">
        <property type="entry name" value="rmlA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0548">Nucleotidyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="NTP_transferase" evidence="6">
        <location>
            <begin position="2"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001095"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003706"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL78860.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="295" mass="32856" checksum="1063FA8B09EF1011" modified="2016-01-20" version="1">MKGIILAGGKGTRLYPITRAVSKQLLPVFNKPMIYYPLSMLMLAGIHEILVISTPDDLPQFKRLLGDGKQWGLSFSYAEQAEPRGLAEAFIIGKDFIGEDKVALVLGDNIFFGHSMPEKLREAALLTSGAVIFAYAVKDPERYGVVHFDENYKALGIEEKPKNPKSNYAVPGIYFYDNQVVRIASELKPSARGELEITDLNRVYLANEQLNVKLLGRGVAWLDAGTHEALLQASNFVETVEQRQGMLISCPEEIAYRMGFIDASQLRKLAQELPQKDFGEYLLDLLNDDGAGRLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YBT4</accession>
    <name>A0A0P6YBT4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_02900</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000013">
        <property type="protein sequence ID" value="KPL79408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02900"/>
    <dbReference type="EnsemblBacteria" id="KPL79408">
        <property type="protein sequence ID" value="KPL79408"/>
        <property type="gene ID" value="ADN00_02900"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="160"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="197"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="228"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="284"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="329"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="365"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="391"/>
            <end position="411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="428" mass="47114" checksum="2FDC3C69AD9CBF75" modified="2016-01-20" version="1">MPLPNSLNNSTGKIQIYFFWGDGCPHCAEEEQYLAEALNRLPISVHSFETWYNNDNKVLYERMAEAYGFEANYVPATFIGDQYWIGFSEQIQAEIEQKLQSYTADPAKAPDAASGILIRNSSTFAPDPNYSGPIEKPVQGQANTLTLPVLGTVNLAEQSIVASTALIALVDGVNPCSVWVLSVLLALTLHTGSRKKVLIIGLTFITVTAAIYAIFIAGVFTILSFVSFIQWIQILIATMAMFFALVNIKDYFWYKEGLSFTIAESDKPGIYKGMRRVLNAGQSIWALIGATIVLAAGVSLVEFSCTAGFPVLWSNLLVSQNVPHSEFIWLILLYMLIYQLDELVFFGVAVVTLRATKIEEKHGRILKLFSGLLMLSLSVVMVINPELMNDLANALIIFGSVIGATILITLLHQQVLPKLGISIGNELK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YF91</accession>
    <name>A0A0P6YF91_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_01200</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000003">
        <property type="protein sequence ID" value="KPL80835.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061136.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000003.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80835">
        <property type="protein sequence ID" value="KPL80835"/>
        <property type="gene ID" value="ADN00_01200"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024623">
        <property type="entry name" value="YtxH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12732">
        <property type="entry name" value="YtxH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="7"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="105"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="48"/>
            <end position="90"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL80835.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="127" mass="13510" checksum="EFB7EE8415DD18C9" modified="2016-01-20" version="1">MSDRDEFGAFLIGFIVGGLTGAVTALLLAPQSGEETRELIKEKAIEISDKASQNLDEAYSQAEAATAEARKKLEELAKTAKEYAQDVQSQGQVLLEEQKAKLGKVLKTKEGTESSPAEPEAPAESAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YG03</accession>
    <name>A0A0P6YG03_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">POR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_00760</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061101.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00760"/>
    <dbReference type="EnsemblBacteria" id="KPL81145">
        <property type="protein sequence ID" value="KPL81145"/>
        <property type="gene ID" value="ADN00_00760"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3550"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016903">
        <property type="term" value="F:oxidoreductase activity, acting on the aldehyde or oxo group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.920.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019752">
        <property type="entry name" value="Pyrv/ketoisovalerate_OxRed_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002869">
        <property type="entry name" value="Pyrv_flavodox_OxRed_cen"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01558">
        <property type="entry name" value="POR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53323">
        <property type="entry name" value="SSF53323"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="POR" evidence="2">
        <location>
            <begin position="16"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01558"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL81145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="200" mass="21291" checksum="E1D1AD6DE3FDCC6B" modified="2016-01-20" version="1">MDATEKPVRFFLVGVGGQGTILASDVLAEVGLKCGYDVKKAEIHGMSQRGGSVVSNVVWARQVFSPIISVGEADVLIAFEKLEALRFLPFLQPGGLLLVNDYSIAPVTVSAGVALYPKDDALYSQLRQRSQSQTWVKGVELADSLGSAKAANVVLLGSLSALISGDADVWLEAVLQRVPAKFADLNKKAFEAGRAVVMEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GKL3</accession>
    <name>A0A0N8GKL3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">XRE family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_18305</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70018.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064493.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18305"/>
    <dbReference type="EnsemblBacteria" id="KPL70018">
        <property type="protein sequence ID" value="KPL70018"/>
        <property type="gene ID" value="ADN00_18305"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2968"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="4"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="5">
        <location>
            <begin position="134"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="3">
        <location>
            <begin position="134"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL70018.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="233" mass="26788" checksum="E77CC8ABE6CAA6BD" modified="2016-01-20" version="1">MSEKVLVVEDEISLQETLAYNLRKQGYEVDTAGEGQTALDKARAWNPDLIILDIMLPGIDGFEICRILRQEMSTPVLMLTARDDEIDRVVGLEVGADDYLTKPFSMRELMARVKAMLRRVRLIREEMDTTAVTAEVIIFGNLNVNLTRREALIDEKPIALKPKEYELLVFLAQHRGQVLTREFILERVWGWDFIGDSRTVDVHVRWLREKIEADPANPMRIITVRGAGYRFEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GL12</accession>
    <name>A0A0N8GL12_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Methyltransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_17570</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000042">
        <property type="protein sequence ID" value="KPL71210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064358.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000042.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17570"/>
    <dbReference type="EnsemblBacteria" id="KPL71210">
        <property type="protein sequence ID" value="KPL71210"/>
        <property type="gene ID" value="ADN00_17570"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2777"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031419">
        <property type="term" value="F:cobalamin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.30.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006158">
        <property type="entry name" value="Cobalamin-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025274">
        <property type="entry name" value="DUF4070"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034530">
        <property type="entry name" value="HpnP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023404">
        <property type="entry name" value="rSAM_horseshoe"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02310">
        <property type="entry name" value="B12-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13282">
        <property type="entry name" value="DUF4070"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00303">
        <property type="entry name" value="hopanoid_C2-methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Radical SAM core" evidence="2">
        <location>
            <begin position="159"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001966"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL71210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="494" mass="57110" checksum="D2A6F70FC4B5CEA8" modified="2016-01-20" version="1">MNILLVYPEFPDTFWSFKHALKFIHKKASSPPLGLLTVAAMLPAEWDKRLVDMNVRPLRPADLDWADMVWISAMVVQRDSVLEVIERCQHKQKKIVAGGPLFTCESSRFSMVDHLILNEGEITLPRFLADLEAGSPQRVYATSEFADLHQTPTPLWNLVDMRKYDSLSIQFTRGCPFNCEFCNVTALLGHRVRTKTTRQIITELDLIYSLGWRRNIFFVDDNFIGNRRLLKEEILPALIEWRKNKIGCRFITEASINLADDEELMDLMVRAGFVSVFVGIETPDENSLAECHKVQNKNRNLVESVRYLQRKGLQVMGGFIVGFDSDTPSIFQRQIEFIQNSGIITAMVGLLQAPNGTQLYQRMQAEGRLIEEMTGDNTDGTTNIVPLMDQNLLHNGYRSILATIYSPKMFYQRVRTFLKEYHLPPVDLHLELAEIGAFFRSIWLLGIWGPERREYWRLFFWTLFHCPQKFPLAITFSIYGYHFRRVSQIQGLTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GL47</accession>
    <name>A0A0N8GL47_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">FliMN_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_17210</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FliN/MopA/SpaO family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17210"/>
    <dbReference type="EnsemblBacteria" id="KPL71490">
        <property type="protein sequence ID" value="KPL71490"/>
        <property type="gene ID" value="ADN00_17210"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.504"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003774">
        <property type="term" value="F:cytoskeletal motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071973">
        <property type="term" value="P:bacterial-type flagellum-dependent cell motility"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006935">
        <property type="term" value="P:chemotaxis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.330.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012826">
        <property type="entry name" value="FliN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001543">
        <property type="entry name" value="FliN-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001172">
        <property type="entry name" value="FliN_T3SS_HrcQb"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036429">
        <property type="entry name" value="SpoA-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01052">
        <property type="entry name" value="FliMN_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00956">
        <property type="entry name" value="FLGMOTORFLIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101801">
        <property type="entry name" value="SSF101801"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02480">
        <property type="entry name" value="fliN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4" id="KW-0145">Chemotaxis</keyword>
    <keyword evidence="5" id="KW-0283">Flagellar rotation</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="20"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="domain" description="FliMN_C" evidence="8">
        <location>
            <begin position="32"/>
            <end position="102"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022779"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF01052"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL71490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="109" mass="11907" checksum="CEC0E3219F496C25" modified="2016-01-20" version="1">MMNDEMSNNGNGMMDEGLSAAAMGVSMANIDMLMDVPLFITVELGRTKMLLQQALELQSGSVIELDRMAGDPIDVFINDRLIARGEVVVVDDKFAVRITELVTSKPKSE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GLW0</accession>
    <name>A0A0N8GLW0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">A_deaminase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_14740</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000035">
        <property type="protein sequence ID" value="KPL73594.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063795.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000035.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14740"/>
    <dbReference type="EnsemblBacteria" id="KPL73594">
        <property type="protein sequence ID" value="KPL73594"/>
        <property type="gene ID" value="ADN00_14740"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2114"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019239">
        <property type="term" value="F:deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001365">
        <property type="entry name" value="A_deaminase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006330">
        <property type="entry name" value="Ado/ade_deaminase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11409">
        <property type="entry name" value="PTHR11409"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00962">
        <property type="entry name" value="A_deaminase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01430">
        <property type="entry name" value="aden_deam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="A_deaminase" evidence="4">
        <location>
            <begin position="17"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="298"/>
            <end position="325"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL73594.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="350" mass="38139" checksum="AD816FF915ECD89E" modified="2016-01-20" version="1">MESPDHPLAAQCLQTLPKIELHRHLEGSLRISTLRQIARQHNLPFPSNADLPALVQIQAGEPLTFANFLSKFQPLRQFYQSPQIITRVVEEVIADAAADQVRHLELRFTPAALARAQGFPLNEVMDWVIESARRAASQRGLSLALIASFNRHEPLELARQVTALSADRAGSGIDGLDLAGNEAEFSALPFAGLLREAKQSGLRLTIHAGEWGGAANVREAIQDLNADRIGHGVRVLEDSSATALARERQITFEVCVTSNVQSGVCPSVLAHPIRGMLAAGLNATFNTDDPSISNIDLTHEYRLAVQELQLTLAQLKDRVLAAARASFLPPAKRQTLCDSLEIELAQQIST</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMT1</accession>
    <name>A0A0N8GMT1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 6 9">50S ribosomal protein L22</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="primary">rplV</name>
        <name evidence="10" type="ORF">ADN00_12575</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">The globular domain of the protein is located near the polypeptide exit tunnel on the outside of the subunit, while an extended beta-hairpin is found that lines the wall of the exit tunnel in the center of the 70S ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="5">This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g. L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.</text>
    </comment>
    <comment type="function">
        <text evidence="6 9">This protein binds specifically to 23S rRNA; its binding is stimulated by other ribosomal proteins, e.g., L4, L17, and L20. It is important during the early stages of 50S assembly. It makes multiple contacts with different domains of the 23S rRNA in the assembled 50S subunit and ribosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="6 8">Part of the 50S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 6 7">Belongs to the universal ribosomal protein uL22 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063365.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12575"/>
    <dbReference type="EnsemblBacteria" id="KPL76162">
        <property type="protein sequence ID" value="KPL76162"/>
        <property type="gene ID" value="ADN00_12575"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3996"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015934">
        <property type="term" value="C:large ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00336">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.470.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01331_B">
        <property type="entry name" value="Ribosomal_L22_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001063">
        <property type="entry name" value="Ribosomal_L22"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036394">
        <property type="entry name" value="Ribosomal_L22/L17_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005727">
        <property type="entry name" value="Ribosomal_L22_bac/chlpt-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13501">
        <property type="entry name" value="PTHR13501"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00237">
        <property type="entry name" value="Ribosomal_L22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54843">
        <property type="entry name" value="SSF54843"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01044">
        <property type="entry name" value="rplV_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="3 6 7" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="6 8" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 8" id="KW-0699">rRNA-binding</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00021205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00025084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU004005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU004008"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL76162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="113" mass="12708" checksum="A7EAD6AA7A3753EA" modified="2016-01-20" version="1">MATDIRAKLSNCGISAQKARLVIDTVRGKAAVEAIDLLRFTNKAAALPVRKLIASAVANAEENFGLSRDDLYVYKITADEAPTRRWRRFGARGRFKPILRRSSHIEVVLRERK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GMX5</accession>
    <name>A0A0N8GMX5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Probable lipid II flippase MurJ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">murJ</name>
        <name evidence="10" type="ORF">ADN00_11115</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 9">Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the MurJ/MviN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063084.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11115"/>
    <dbReference type="EnsemblBacteria" id="KPL76514">
        <property type="protein sequence ID" value="KPL76514"/>
        <property type="gene ID" value="ADN00_11115"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015648">
        <property type="term" value="F:lipid-linked peptidoglycan transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13123">
        <property type="entry name" value="MATE_MurJ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02078">
        <property type="entry name" value="MurJ_MviN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004268">
        <property type="entry name" value="MurJ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03023">
        <property type="entry name" value="MurJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002869">
        <property type="entry name" value="MviN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01806">
        <property type="entry name" value="VIRFACTRMVIN"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01695">
        <property type="entry name" value="murJ_mviN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 8 9" id="KW-0133">Cell shape</keyword>
    <keyword evidence="8 9" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7 8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 8 9" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="63"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="99"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="143"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="170"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="196"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="248"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="288"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="320"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="360"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="394"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="428"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="458"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="488"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR002869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL76514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="531" mass="56607" checksum="46A45DCDB902ED52" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GN39</accession>
    <name>A0A0N8GN39_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10705</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the ROK (NagC/XylR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062989.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77026">
        <property type="protein sequence ID" value="KPL77026"/>
        <property type="gene ID" value="ADN00_10705"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000600">
        <property type="entry name" value="ROK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18964">
        <property type="entry name" value="PTHR18964"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00480">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01125">
        <property type="entry name" value="ROK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006479"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="400" mass="41913" checksum="DD4852EEF42585B0" modified="2016-01-20" version="1">MPISPTGNRDLIRAINSTLVLNTVRTLGPISRTEIAQRTGLSAATITGISAELIEKDLIFEKATGDSSGGRRPILLDLNPRGGFVIGLKLTEDHITAALTDLRAVVVAKQTFPLTGKSVEEGVAALCGAVTSLAAAHQVPAGRLLGVGVGLAGVVNAETGVLRHSPIIGWNNVPLASRMQASLSVPVYVDNDVNTFTLTEKWFGVGQKVENFLVVTIGRGVGMGIVVNGQLYRGGRGGAGELGHTVVSPDGPLCGCGKHGCLETFVADPAMLRDARLAFEQGRLERLPATTRELAEMAEQGSPAAQSILAAAGEILGRSLANLINIFNPTLVVISGEGVGAGDFFFNAMRQQVQLHSMDGLASDAEIKIDVWEDDAWARGAAGLVLHGIFESPIYREQAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GN79</accession>
    <name>A0A0N8GN79_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Probable lipid II flippase MurJ</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="primary">murJ</name>
        <name evidence="10" type="ORF">ADN00_09525</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="10 11" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="10 11">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8 9">Involved in peptidoglycan biosynthesis. Transports lipid-linked peptidoglycan precursors from the inner to the outer leaflet of the cytoplasmic membrane.</text>
    </comment>
    <comment type="pathway">
        <text evidence="8">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Cell membrane</location>
            <topology evidence="8">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8 9">Belongs to the MurJ/MviN family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062756.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09525"/>
    <dbReference type="EnsemblBacteria" id="KPL77346">
        <property type="protein sequence ID" value="KPL77346"/>
        <property type="gene ID" value="ADN00_09525"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005887">
        <property type="term" value="C:integral component of plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015648">
        <property type="term" value="F:lipid-linked peptidoglycan transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071555">
        <property type="term" value="P:cell wall organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008360">
        <property type="term" value="P:regulation of cell shape"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13123">
        <property type="entry name" value="MATE_MurJ_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02078">
        <property type="entry name" value="MurJ_MviN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004268">
        <property type="entry name" value="MurJ"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03023">
        <property type="entry name" value="MurJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF002869">
        <property type="entry name" value="MviN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01806">
        <property type="entry name" value="VIRFACTRMVIN"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01695">
        <property type="entry name" value="murJ_mviN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8 9" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="4 8 9" id="KW-0133">Cell shape</keyword>
    <keyword evidence="8 9" id="KW-0961">Cell wall biogenesis/degradation</keyword>
    <keyword evidence="7 8 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 8 9" id="KW-0573">Peptidoglycan synthesis</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="58"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="101"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="145"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="201"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="287"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="330"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="362"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="396"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="427"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="459"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="489"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022960"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_02078"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR002869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KPL77346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="533" mass="56892" checksum="C1236CC6CEF22009" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNP9</accession>
    <name>A0A0N8GNP9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_05520</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78706.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061975.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05520"/>
    <dbReference type="EnsemblBacteria" id="KPL78706">
        <property type="protein sequence ID" value="KPL78706"/>
        <property type="gene ID" value="ADN00_05520"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003838">
        <property type="entry name" value="ABC3_permease_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025857">
        <property type="entry name" value="MacB_PCD"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02687">
        <property type="entry name" value="FtsX"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12704">
        <property type="entry name" value="MacB_PCD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="248"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="292"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="336"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="404"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="626"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="671"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="719"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="18"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="277"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="domain" description="MacB_PCD" evidence="8">
        <location>
            <begin position="403"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="domain" description="FtsX" evidence="7">
        <location>
            <begin position="656"/>
            <end position="747"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF12704"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL78706.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="754" mass="81492" checksum="13D27326D48E130D" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GPI5</accession>
    <name>A0A0N8GPI5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_00100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL80994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075060924.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00100"/>
    <dbReference type="EnsemblBacteria" id="KPL80994">
        <property type="protein sequence ID" value="KPL80994"/>
        <property type="gene ID" value="ADN00_00100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018580">
        <property type="entry name" value="Uncharacterised_YfhO"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38454">
        <property type="entry name" value="PTHR38454"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="122"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="184"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="228"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="291"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="321"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="355"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="387"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="414"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="440"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="680"/>
            <end position="699"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="705" mass="77623" checksum="0AA747DFDA6DFC9B" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="24" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GPJ7</accession>
    <name>A0A0N8GPJ7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 14">Indolepyruvate oxidoreductase subunit IorA</fullName>
            <shortName evidence="14">IOR</shortName>
            <ecNumber evidence="3 14">1.2.7.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12 14">Indolepyruvate ferredoxin oxidoreductase subunit alpha</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">ADN00_00765</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="17 18" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="17 18">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 14">Catalyzes the ferredoxin-dependent oxidative decarboxylation of arylpyruvates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="13 14">
            <text>CoA + indole-3-pyruvate + 2 oxidized [2Fe-2S]-[ferredoxin] = (indol-3-yl)acetyl-CoA + CO2 + H(+) + 2 reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:12645"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:17640"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57271"/>
            <dbReference type="ChEBI" id="CHEBI:57287"/>
            <dbReference type="EC" id="1.2.7.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="14 15">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="14 15">Binds 2 [4Fe-4S] clusters. In this family the first cluster has a non-standard and varying [4Fe-4S] binding motif CX(2)CX(2)CX(4-5)CP.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Heterodimer of the IorA and IorB subunits.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.2.7.8" evidence="3 14"/>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00765"/>
    <dbReference type="EnsemblBacteria" id="KPL81090">
        <property type="protein sequence ID" value="KPL81090"/>
        <property type="gene ID" value="ADN00_00765"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3551"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043805">
        <property type="term" value="F:indolepyruvate ferredoxin oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07034">
        <property type="entry name" value="TPP_PYR_PFOR_IOR-alpha_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045025">
        <property type="entry name" value="HACL1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017721">
        <property type="entry name" value="IorA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002880">
        <property type="entry name" value="Pyrv_Fd/Flavodoxin_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009014">
        <property type="entry name" value="Transketo_C/PFOR_II"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43710">
        <property type="entry name" value="PTHR43710"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00037">
        <property type="entry name" value="Fer4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01855">
        <property type="entry name" value="POR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006439">
        <property type="entry name" value="Indolepyruvate_ferr_oxidored"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52922">
        <property type="entry name" value="SSF52922"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR03336">
        <property type="entry name" value="IOR_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 14 15" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="8 14" id="KW-0249">Electron transport</keyword>
    <keyword evidence="10 14 15" id="KW-0408">Iron</keyword>
    <keyword evidence="11 14 15" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="7 14 15" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9 14" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 14" id="KW-0813">Transport</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="16">
        <location>
            <begin position="553"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="16">
        <location>
            <begin position="589"/>
            <end position="618"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002995"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011238"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012812"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00017710"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022485"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00033657"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRNR" id="PIRNR006439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="PIRSR" id="PIRSR006439-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KPL81090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="626" mass="68459" checksum="2313065E6B9F2667" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WLV0</accession>
    <name>A0A0P6WLV0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_17975</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000044">
        <property type="protein sequence ID" value="KPL70765.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70765">
        <property type="protein sequence ID" value="KPL70765"/>
        <property type="gene ID" value="ADN00_17975"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70765.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="143" mass="16160" checksum="6CDD0F413A17F8D8" modified="2016-01-20" version="1">MGRALQQPVIIESCTNQLSQAGAGISNHPPLSRQSRKVNRNWMKEEMKGGKKVCDIYSSPGMGTIISANQMRKAVLSKGFNPFKMGLTNTPAIMMVGEQAAYQHWRSMIVAQSTSDWNICAKCMAKLKPYLSEKSKMWWQFWK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WR49</accession>
    <name>A0A0P6WR49_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Exodeoxyribonuclease 7 large subunit</fullName>
            <ecNumber evidence="5">3.1.11.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Exodeoxyribonuclease VII large subunit</fullName>
            <shortName evidence="5">Exonuclease VII large subunit</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">xseA</name>
        <name evidence="9" type="ORF">ADN00_16795</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5 6">
            <text>Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates.</text>
            <dbReference type="EC" id="3.1.11.6"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="5">Heterooligomer composed of large and small subunits.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5 6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 6">Belongs to the XseA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.11.6" evidence="5"/>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064208.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16795"/>
    <dbReference type="EnsemblBacteria" id="KPL71365">
        <property type="protein sequence ID" value="KPL71365"/>
        <property type="gene ID" value="ADN00_16795"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.419"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009318">
        <property type="term" value="C:exodeoxyribonuclease VII complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008855">
        <property type="term" value="F:exodeoxyribonuclease VII activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006308">
        <property type="term" value="P:DNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd04489">
        <property type="entry name" value="ExoVII_LU_OBF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00378">
        <property type="entry name" value="Exonuc_7_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003753">
        <property type="entry name" value="Exonuc_VII_L"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020579">
        <property type="entry name" value="Exonuc_VII_lsu_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025824">
        <property type="entry name" value="OB-fold_nuc-bd_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30008">
        <property type="entry name" value="PTHR30008"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02601">
        <property type="entry name" value="Exonuc_VII_L"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13742">
        <property type="entry name" value="tRNA_anti_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00237">
        <property type="entry name" value="xseA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 5 6" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="3 5 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 5 6" id="KW-0540">Nuclease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="tRNA_anti_2" evidence="8">
        <location>
            <begin position="13"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="Exonuc_VII_L" evidence="7">
        <location>
            <begin position="131"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="domain" description="Exonuc_VII_L" evidence="7">
        <location>
            <begin position="341"/>
            <end position="400"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00378"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004355"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF02601"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF13742"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL71365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="413" mass="45545" checksum="D5BDE55566AF371F" modified="2016-01-20" version="1">MEPLPFFKTPLTLTVEEITRYIRQMMESDEVLRDVRVLGEVSNLSMPKSGHIYFTLKDHAAQLRCVIWRSQAVRIRFALQDGMAVEAHGAISVYERDGQYQLYVFTLQPVGEGLLYQEFLRLKAMLEAEGLFDEARKRPLPAFPQKIGIISSPTGAALQDMLNTLRTRYPIAEVILAPSAVQGAEAPAELVRALRCLNGLPDLDVILLARGGGSLEDLWAFNDELVVRAVASSRVPVISGVGHETDFTLVDFAADFRAPTPTGAAVAATPDRKDLLLNLLDARMDLLGAYTTRVSTARERLSNLQQRLLRASPVRRIQDSHQALDQLSARALRAAGQRIKWEHSRLTATSERLSALNPANVLQRGYAILNLPDGSLLKSVAQAPAGQDFQVQLSDGRFSARAVESPLSTPQKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WTU2</accession>
    <name>A0A0P6WTU2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_19135</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70148.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064641.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70148">
        <property type="protein sequence ID" value="KPL70148"/>
        <property type="gene ID" value="ADN00_19135"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70148.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="86" mass="9466" checksum="BB0395065D94C456" modified="2016-01-20" version="1">MVNRKPAALVMIVVLVALFLMSMACGPVNDLVQKRIRETQAAWTAVPTAEPCVCEEEEGEGDMQPTYTPYPTYTPYAVDAPPAFYP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WU46</accession>
    <name>A0A0P6WU46_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 5">Argininosuccinate lyase</fullName>
            <shortName evidence="5">ASAL</shortName>
            <ecNumber evidence="3 5">4.3.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Arginosuccinase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">argH</name>
        <name evidence="8" type="ORF">ADN00_14415</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>2-(N(omega)-L-arginino)succinate = fumarate + L-arginine</text>
            <dbReference type="Rhea" id="RHEA:24020"/>
            <dbReference type="ChEBI" id="CHEBI:29806"/>
            <dbReference type="ChEBI" id="CHEBI:32682"/>
            <dbReference type="ChEBI" id="CHEBI:57472"/>
            <dbReference type="EC" id="4.3.2.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Amino-acid biosynthesis; L-arginine biosynthesis; L-arginine from L-ornithine and carbamoyl phosphate: step 3/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the lyase 1 family. Argininosuccinate lyase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.3.2.1" evidence="3 5"/>
    <dbReference type="EMBL" id="LGCL01000034">
        <property type="protein sequence ID" value="KPL73773.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14415"/>
    <dbReference type="EnsemblBacteria" id="KPL73773">
        <property type="protein sequence ID" value="KPL73773"/>
        <property type="gene ID" value="ADN00_14415"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1403"/>
    <dbReference type="UniPathway" id="UPA00068">
        <property type="reaction ID" value="UER00114"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004056">
        <property type="term" value="F:argininosuccinate lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042450">
        <property type="term" value="P:arginine biosynthetic process via ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01359">
        <property type="entry name" value="Argininosuccinate_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.275.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00006">
        <property type="entry name" value="Arg_succ_lyase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029419">
        <property type="entry name" value="Arg_succ_lyase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009049">
        <property type="entry name" value="Argininosuccinate_lyase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024083">
        <property type="entry name" value="Fumarase/histidase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020557">
        <property type="entry name" value="Fumarate_lyase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000362">
        <property type="entry name" value="Fumarate_lyase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022761">
        <property type="entry name" value="Fumarate_lyase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008948">
        <property type="entry name" value="L-Aspartase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43814">
        <property type="entry name" value="PTHR43814"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14698">
        <property type="entry name" value="ASL_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00206">
        <property type="entry name" value="Lyase_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00149">
        <property type="entry name" value="FUMRATELYASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48557">
        <property type="entry name" value="SSF48557"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00838">
        <property type="entry name" value="argH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00163">
        <property type="entry name" value="FUMARATE_LYASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="4 5" id="KW-0055">Arginine biosynthesis</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 8" id="KW-0456">Lyase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lyase_1" evidence="6">
        <location>
            <begin position="9"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="domain" description="ASL_C2" evidence="7">
        <location>
            <begin position="356"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004941"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012338"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022571"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00006"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF14698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL73773.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="454" mass="49014" checksum="4EF7170F0F6E91C4" modified="2016-01-20" version="1">MSGSLNAAAAALNSSLAVDVNMAQQDVRGSQAWARALARSGLITKEDLYAILGGLETISKELASETFLFAESDEDIHTAVERRLTELIGAPAGKLHTGRSRNDQVVTDFRLWMLDAIQAADSGLAGVQSALLERAEADWGVILPGYTHFQQAQPLLLSHWWMAHFWALQRDRERLVDLKQETGVLPLGCGALAGSGFVIDRFALAADLGFAAPAPNSVDAVSDRDFALDFLHCASMIGLHLSRLAEALILYSTREFGFITFADEYSTGSSLMPQKKNPDPMELVRGKSGVLIGLQTGLMAVVKATPSAYDKDLQEDKAPVMEAASLLEMLLPVTAGALRTLQVNREKIAAALDPAMLATDLADYLVEKGVPFREAYQAVGAAVRWSVEQGVSVCDLPLETWRGLHPAFAADVKEVFQFPRAVARRASWGGTAPEAVRLQMERARKMLALGGGQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WVY8</accession>
    <name>A0A0P6WVY8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_18965</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70124">
        <property type="protein sequence ID" value="KPL70124"/>
        <property type="gene ID" value="ADN00_18965"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="117" mass="13596" checksum="865F116E55F80A3C" modified="2016-01-20" version="1">MKFETNQKQLGWRLEYLQAPGNQCCSKSNPALVQLYQFESKLDLLKKLTRLLQNRIQKNDPAAKLDLILLLPAFLCYLHKLQVHSRLQKSPRNLANIAPYWTSQIHTMALHQKGRNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WXX2</accession>
    <name>A0A0P6WXX2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HisKA_3 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_17575</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000042">
        <property type="protein sequence ID" value="KPL71227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17575"/>
    <dbReference type="EnsemblBacteria" id="KPL71227">
        <property type="protein sequence ID" value="KPL71227"/>
        <property type="gene ID" value="ADN00_17575"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="20"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="96"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="domain" description="HisKA_3" evidence="3">
        <location>
            <begin position="180"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="144"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL71227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="384" mass="42026" checksum="470E556BB5043400" modified="2016-01-20" version="1">MVLTAYFATFSTLREVSSLKLFLLIVFGIGYMSLGVYGYGYVARGHSMNLRLLYFALQIPLGGLIIFFSQGTGVNVMVLLPLVGHSVLLLADTWRYVVNVVILLAYTVAVYLITGSVAETWSGLLLFFAGQVFIVVFTQMAVDEERAREKVVGLVEELEAANQRLREFALQVEELAITRERNRLAREIHDGLGHYLTTINIQLKAAQAVLSSDPARAVSAIDTAQNLAQEALVDVRRSVGALRASPEEDLPLDEQLGRLLARCQAAGVEPHLRVIGTPRPLSPQVHLTLYRAAQEGLNNVCKHAQANHLWAELDYSQPGSVRLFLRDNGQGAHTLDGGFGLLGLRERVHLLNGVFRVESQAGNGVTLEIVVPQDDKENSNSAGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WY35</accession>
    <name>A0A0P6WY35_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_17340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71449.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064311.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL71449">
        <property type="protein sequence ID" value="KPL71449"/>
        <property type="gene ID" value="ADN00_17340"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.2880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038468">
        <property type="entry name" value="MmpS_C"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="13"/>
            <end position="38"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL71449.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="133" mass="14000" checksum="4DBF4284BD764EB8" modified="2016-01-20" version="1">MSPSTAASKRSQIVLQVLALVVLCAVLAGLAVVFDIFAPTASEHLITMRVETSGGYAQITYKDATGKLLEAETVSTPWERSAVNPSGTQVYLTAANPTGSGSIQCALKLDRKEWKTDKAQFPDDSVACGGIVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZA3</accession>
    <name>A0A0P6WZA3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_16465</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16465"/>
    <dbReference type="EnsemblBacteria" id="KPL72068">
        <property type="protein sequence ID" value="KPL72068"/>
        <property type="gene ID" value="ADN00_16465"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="416" mass="45673" checksum="812C9A0E3BA94610" modified="2016-01-20" version="1">MYSETDMVLGSPDVDMCGDAFAAWTNLNPETSPSEYFLQLTYPYRVSMTEVNVVISGNPGGRMRVEVLDSSSGLGREIFNGNADTDGACPGIFTIPVSENLSVDTVILTFSNTDQPMQIDAVELVGNLTGFVDLPVFWRIPIPADSLSDADSQFPGGIAVDPLENSLFLANGRNGLYRYDVEGNLLKTYSVPSESNLRDVAADRFGMIVVTDNVYQWYISMLFDGTQVVAGGEDFAWNYPKAVAISPYDGNVYLLDESEETSRIRVYTSDTGDWVRDIYLEPRGIDGYKGLAFDPDAYLYISDQIEGGLLRIEPMTGAILDTIGYLELAPSSVSDLAIDDHGNFYVLMSTSPDDSAVYVLNPQGTLIGRFGHLNYDGSDWSEGTFQLPVGIAVTGDGRFVFICENGFLTAYRWEEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="26" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZD2</accession>
    <name>A0A0P6WZD2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">LuxR family transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_16620</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064162.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16620"/>
    <dbReference type="EnsemblBacteria" id="KPL72123">
        <property type="protein sequence ID" value="KPL72123"/>
        <property type="gene ID" value="ADN00_16620"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="2" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="5"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="domain" description="HTH luxR-type" evidence="3">
        <location>
            <begin position="141"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="4">
        <location>
            <begin position="237"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="56"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="2">
        <location>
            <position position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL72123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="355" mass="40046" checksum="6D7521B612725AD5" modified="2016-01-20" version="1">MKKIRVLIADDHDLIRKGIRGVLEEFQDFEIVGEAGDGPTLFQLIPRTRPDCVLIDVAMPDFEPISAIQKIHQEFPEIRLLVVSAYDDNIYVQGLLAAGVSGYHLKGQSLNDLVLAIRRILRGERWLSGPLVEKLIDQRVSKSSHNRLTERQTELLSLLQQGLDNKSIAQQLQISVKTVENSLTRLYFVLNVQSRLEAVRYANEHPDLFPSHSNIETQKTVVPELAPPMPSTSSSISILLIDDNNHYRNQFCKTVKIANPHAVVFEADNIESAVDLVQNRDIQLAFVDMILGRESGIICTQRIKEISPQSRIILMSAYPDREFRRQGLAAGALVFVDKKDIDLSTLRQIIQDVNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="6" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZK7</accession>
    <name>A0A0P6WZK7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_15715</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72263.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72263">
        <property type="protein sequence ID" value="KPL72263"/>
        <property type="gene ID" value="ADN00_15715"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72263.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="147" mass="16148" checksum="22B51F42A7E9EE60" modified="2016-01-20" version="1">MALTRAQIETVLIARCGGKMTVAGLDGATHDGNNADLVDPISASLFEMGYQLDIGTVTDSVLSIVEGNRISEFLDRAERRCLENISGNIDTVNIALGPRREDLNQLAEQVEKAIARLEKKILLRYGDAPLVGDTIRLDFQEKNEDYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X148</accession>
    <name>A0A0P6X148_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_12025</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063260.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12025"/>
    <dbReference type="EnsemblBacteria" id="KPL76068">
        <property type="protein sequence ID" value="KPL76068"/>
        <property type="gene ID" value="ADN00_12025"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004104">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="1"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA_C" evidence="2">
        <location>
            <begin position="128"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL76068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="328" mass="36501" checksum="8E7287A20BB0F75C" modified="2016-01-20" version="1">MKFLIAGFGSIGRRHLRNLRALGHEDIVLLRSHRSTLPDDEIAGLPVETELEKALAHRPDGVVIANPTALHLPVAIPAARAGCSILMEKPVSDSLEGIDELRRALDEGKSSLLVGFQFRFHPGLNKIKELIDTQAVGRILSARCQWGEYLPGWHPWEDYRQGYAARRDLGGGVVRTLTHPFDYLRWLLGDVVSLSAVVGQLSDLELDVEDMAEVSLGFAGGAQASVQVNYYQRPPVHRLELVGTHGTLAWDNAEGAARLWQEESRQWETFPLAEGFDRNDLFLAETRHFIDVIQGKASPVCTLEDGEKVMEIVEAIFRSSAERRTVQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X192</accession>
    <name>A0A0P6X192_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_12350</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76123.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063320.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76123">
        <property type="protein sequence ID" value="KPL76123"/>
        <property type="gene ID" value="ADN00_12350"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="124"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76123.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="124" mass="14182" checksum="8E53388E350FF660" modified="2016-01-20" version="1">MSENPNPDLSDELRQFGQSLKNFFKSAWESQERQQIQNEIEHSLDEVARALNQAADDFTQSRQGQQLKAEFDDLKQRVESGELSDKIQNDLKNTLRQVTQELDQAASRWSQPSSAGDESEQQPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X1W8</accession>
    <name>A0A0P6X1W8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Glutaconyl-CoA decarboxylase subunit beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_10965</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063055.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10965"/>
    <dbReference type="EnsemblBacteria" id="KPL76488">
        <property type="protein sequence ID" value="KPL76488"/>
        <property type="gene ID" value="ADN00_10965"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.886"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016829">
        <property type="term" value="F:lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006814">
        <property type="term" value="P:sodium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005661">
        <property type="entry name" value="OadB_MmdB"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35806">
        <property type="entry name" value="PTHR35806"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03977">
        <property type="entry name" value="OAD_beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF015658">
        <property type="entry name" value="MmdB_OadB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01109">
        <property type="entry name" value="Na_pump_decarbB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 7" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="7" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0915">Sodium</keyword>
    <keyword evidence="7" id="KW-0739">Sodium transport</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="7" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="16"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="72"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="103"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="155"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="204"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="251"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="278"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="342"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR015658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL76488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="372" mass="39152" checksum="12F0C9A7A1E00769" modified="2016-01-20" version="1">MNFSDLLSEITRGFTAFYWGNAVMIAIGFVLIGLAVIKEYEPVLLLPIGFGCILANLGMDTSHGVFKVIYDAGIATELFPLLIFIGVGAMIDFRPLLAMPHMVLLGAAGQFGIYGTLILATLLGFPLNQAASIGVIGAIDGPTAIFVASKLAPEMLGPIAVAAYSYMSLVPIIQPPVMRLLTTRKERLIRMDYSARPVSNTAVVLFPIIVTVIISLIAPDAAPLIATLMLGNLLRESGVVERLRKAAENEIINIATLFLGLSIGATMTAQSFLNLQTLAVLALGLLAFVLDTAAGVMFGKLMCFVTGGKINPLIGACGISAFPMAGRLSAQMAQEEDYDNFILMHAMGSNTAGQLGSVIAGGLLLALVSGMI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X3B1</accession>
    <name>A0A0P6X3B1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_09420</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77366.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09420"/>
    <dbReference type="EnsemblBacteria" id="KPL77366">
        <property type="protein sequence ID" value="KPL77366"/>
        <property type="gene ID" value="ADN00_09420"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4119"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015424">
        <property type="term" value="F:ABC-type amino acid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030679">
        <property type="entry name" value="ABC_ATPase_HisP-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF039085">
        <property type="entry name" value="ABC_ATPase_HisP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ABC transporter" evidence="4">
        <location>
            <begin position="2"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="34"/>
            <end position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL77366.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="242" mass="26914" checksum="9DE671F77C84BE77" modified="2016-01-20" version="1">MISMNNVYKHFGPVKALNGVSLEINRGKVVVIIGPSGSGKSTLLRCINHLEVESSGEIFVDGARVNGNQKHLNSVRSQIGMVFQHFNLYPHLTVLENVTLALRVVKKAPRKEAEVIAMKQLERVGIAEKAHNFPTQLSGGQQQRVAIARALAMNPKIMLFDEPTSALDPEMIKEVLDVMLDLAKEGITMVVVTHEMGFARAAADEVIFMDQGIIIEHTTPHDLFNNPRHDRTRLFLSQILHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5B4</accession>
    <name>A0A0P6X5B4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_07020</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Fur family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062272.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78225">
        <property type="protein sequence ID" value="KPL78225"/>
        <property type="gene ID" value="ADN00_07020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07153">
        <property type="entry name" value="Fur_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002481">
        <property type="entry name" value="FUR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043135">
        <property type="entry name" value="Fur_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33202">
        <property type="entry name" value="PTHR33202"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01475">
        <property type="entry name" value="FUR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0862">Zinc</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="137" mass="15855" checksum="C917E25FC19EFACA" modified="2016-01-20" version="1">MQKLRDNGYRLTDAREAVVEVVINSDRVLKPCEVFDLARAHYGKLGLVSVYRTLEKLEELGMIQRVHQHQGCQAFVAAKEGHHHLLLCSVCGRYEYFQGENLESFFAQIGIEKDYQIEEHWMQVFGVCSTCRRQGYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X5C0</accession>
    <name>A0A0P6X5C0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_07100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062287.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78235">
        <property type="protein sequence ID" value="KPL78235"/>
        <property type="gene ID" value="ADN00_07100"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="13"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="53"/>
            <end position="77"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="230" mass="24976" checksum="E1CFB196F794767E" modified="2016-01-20" version="1">MKELIAFLEKFEIWIYAMLGGVGLLYIRKVIVAWNEWRTSVFGMEREASQRRLGTALSVLALAALLALSEFVLISFVSPALPATSLLPTPTLDLLATATPTLPSEAVAEGAAQATLVPNMANLPLTEGCQAGRIEWIEPLEGAEVLSGSVTLKFIVNLDNLGFYKYEYGQPGSDVWTTIAAGNQSSETEQTATWNTDQLVPGDYFLRLVVMDGQNNPQPVCVTSVRIVLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X7G0</accession>
    <name>A0A0P6X7G0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PDDEXK_1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_18825</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70099.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064583.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18825"/>
    <dbReference type="EnsemblBacteria" id="KPL70099">
        <property type="protein sequence ID" value="KPL70099"/>
        <property type="gene ID" value="ADN00_18825"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.320.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011604">
        <property type="entry name" value="PDDEXK-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038726">
        <property type="entry name" value="PDDEXK_AddAB-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12705">
        <property type="entry name" value="PDDEXK_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDDEXK_1" evidence="1">
        <location>
            <begin position="4"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70099.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="265" mass="29646" checksum="E32C060E4B4A4CAC" modified="2016-01-20" version="1">MIEHLSYSSISTYLTCAASWKFHYLDKVTAPTSTALIFGSAFHNTVEGYLAGIANGGKPDLMEIWQEKWREQSTVKNEKGELITREDVDWGADTPESLCNDGIRLLSHDDIHSGILSIIPGVDSSGVKIERKVTLQVPGVPVPIIGFIDIVTADGIPGDFKTSNRSWSAEKALGETQPLFYLAALNQAGIQTPGWKFRHFVFVKTKKPQFQVLEHGHTPGQMMWLFSMIQKVWKGIDAGIFPENPTGWKCDPQYCEYWHLCRGKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X834</accession>
    <name>A0A0P6X834_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_04780</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061814.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79167">
        <property type="protein sequence ID" value="KPL79167"/>
        <property type="gene ID" value="ADN00_04780"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="43"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="105"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="157"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="180"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="220"/>
            <end position="240"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="256" mass="28219" checksum="C218C34640F2D4FA" modified="2016-01-20" version="1">MWFSALDGFIWLAACAIPFWFAQRWLHRELQGVLVLLTRREEIGLAMYALLFFPGVLLHESSHFLAARLLRVRTGKFSLIPRLLPGGRLQLGYVETEKSDLFRDAMIGAAPLFTGGAVMLWLGGQPLGLAPLAGLLSAGDWAALWQALISLPRLPDFWLWFYLAFTISATMLPSASDRYAWLPVLLLAAALLGAALLAGAGNWLQTWLLPLVNRACGSLAVAFGVSLVLHAILLLPLGLLRRLLCRWLGVELAYET</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="32" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X868</accession>
    <name>A0A0P6X868_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Lipoyl synthase</fullName>
            <ecNumber evidence="6">2.8.1.8</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Lip-syn</fullName>
            <shortName evidence="6">LS</shortName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Lipoate synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Lipoic acid synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="6">Sulfur insertion protein LipA</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="6" type="primary">lipA</name>
        <name evidence="9" type="ORF">ADN00_04955</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="6">Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 6">
            <text>[[Fe-S] cluster scaffold protein carrying a second [4Fe-4S](2+) cluster] + 4 H(+) + N(6)-octanoyl-L-lysyl-[protein] + 2 oxidized [2Fe-2S]-[ferredoxin] + 2 S-adenosyl-L-methionine = (R)-N(6)-dihydrolipoyl-L-lysyl-[protein] + 2 5'-deoxyadenosine + [[Fe-S] cluster scaffold protein] + 4 Fe(3+) + 2 hydrogen sulfide + 2 L-methionine + 2 reduced [2Fe-2S]-[ferredoxin]</text>
            <dbReference type="Rhea" id="RHEA:16585"/>
            <dbReference type="Rhea" id="RHEA-COMP:9928"/>
            <dbReference type="Rhea" id="RHEA-COMP:10000"/>
            <dbReference type="Rhea" id="RHEA-COMP:10001"/>
            <dbReference type="Rhea" id="RHEA-COMP:10475"/>
            <dbReference type="Rhea" id="RHEA-COMP:14568"/>
            <dbReference type="Rhea" id="RHEA-COMP:14569"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17319"/>
            <dbReference type="ChEBI" id="CHEBI:29034"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:33722"/>
            <dbReference type="ChEBI" id="CHEBI:33737"/>
            <dbReference type="ChEBI" id="CHEBI:33738"/>
            <dbReference type="ChEBI" id="CHEBI:57844"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:78809"/>
            <dbReference type="ChEBI" id="CHEBI:83100"/>
            <dbReference type="EC" id="2.8.1.8"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
        </cofactor>
        <text evidence="6">Binds 2 [4Fe-4S] clusters per subunit. One cluster is coordinated with 3 cysteines and an exchangeable S-adenosyl-L-methionine.</text>
    </comment>
    <comment type="pathway">
        <text evidence="6">Protein modification; protein lipoylation via endogenous pathway; protein N(6)-(lipoyl)lysine from octanoyl-[acyl-carrier-protein]: step 2/2.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="6">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the radical SAM superfamily. Lipoyl synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.8.1.8" evidence="6"/>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79195.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061845.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04955"/>
    <dbReference type="EnsemblBacteria" id="KPL79195">
        <property type="protein sequence ID" value="KPL79195"/>
        <property type="gene ID" value="ADN00_04955"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.358"/>
    <dbReference type="UniPathway" id="UPA00538">
        <property type="reaction ID" value="UER00593"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051539">
        <property type="term" value="F:4 iron, 4 sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016992">
        <property type="term" value="F:lipoate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102552">
        <property type="term" value="F:lipoyl synthase activity (acting on glycine-cleavage complex H protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102553">
        <property type="term" value="F:lipoyl synthase activity (acting on pyruvate dehydrogenase E2 protein)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009249">
        <property type="term" value="P:protein lipoylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00206">
        <property type="entry name" value="Lipoyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006638">
        <property type="entry name" value="Elp3/MiaB/NifB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003698">
        <property type="entry name" value="Lipoyl_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007197">
        <property type="entry name" value="rSAM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10949">
        <property type="entry name" value="PTHR10949"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04055">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005963">
        <property type="entry name" value="Lipoyl_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00271">
        <property type="entry name" value="lipoyl_synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00029">
        <property type="entry name" value="Radical_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00729">
        <property type="entry name" value="Elp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00510">
        <property type="entry name" value="lipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51918">
        <property type="entry name" value="RADICAL_SAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0004">4Fe-4S</keyword>
    <keyword evidence="6" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 6" id="KW-0408">Iron</keyword>
    <keyword evidence="5 6" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="3 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="6 9" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Radical SAM core" evidence="8">
        <location>
            <begin position="65"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="53"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="58"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="64"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="83"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="86"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>2</label>
            <note>4Fe-4S-S-AdoMet</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="292"/>
        </location>
        <ligand>
            <name>[4Fe-4S] cluster</name>
            <dbReference type="ChEBI" id="CHEBI:49883"/>
            <label>1</label>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001264"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51918"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL79195.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="313" mass="35330" checksum="013A768013841AA9" modified="2016-01-20" version="1">MTTRPPTRDRIPASSPDARPARRPGWIRVPPTDHETLQWLKSLMKQKTLHTVCEEAGCPNISECWGSGTATFLMMGDVCTRACRFCDVKHGRPAPLDWDEPERVAQAVRAMQLKHAVITSVNRDERKDGGAPIFAMVIRRIRELQPGCSVEVLIPDFKGSLEALQIVMDARPEILNHNVETVPSLYPTIQPQSRLEWSEAILRGAKRMDPEVLTKSGIMLGLGESMEEVRAVLRDLREWGVDILTIGQYLQPSRRHAPIARYYTPQEFDELKQFGLDLGFRWVESGPLVRSSYHAAEQVRALSAVHQSLSHPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X875</accession>
    <name>A0A0P6X875_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">2-oxoglutarate oxidoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_16855</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064220.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16855"/>
    <dbReference type="EnsemblBacteria" id="KPL71375">
        <property type="protein sequence ID" value="KPL71375"/>
        <property type="gene ID" value="ADN00_16855"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.431"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TPP_enzyme_C" evidence="1">
        <location>
            <begin position="57"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL71375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="258" mass="28202" checksum="E6684133C50EF52C" modified="2016-01-20" version="1">MSLLEKETAVYERPKSLVDGLTHYCPGCTHGVAHRLVAEVIDEMGVRETTIGVAPVGCAVFAYNYFDFDFVEAAHGRAPAMATGIKRVLPDRMVWTYQGDGDLASIGTAEIVAAAARGENITVIFINNANYGMTGGQMAPTTLPGQVTSSSPSGRDVEMAGYPIRVSEMLSKLEGASYVVRRSLHDPKNIRQAKKAIRTAFEVQRNGLGFAMVELLSSCPTNWGMKPVDALRWIETNMVPFYPLGDYKVNPMVNEMKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X899</accession>
    <name>A0A0P6X899_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_05115</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061877.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79222">
        <property type="protein sequence ID" value="KPL79222"/>
        <property type="gene ID" value="ADN00_05115"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.394"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="SSF54106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132918" description="LysM domain-containing protein" evidence="2">
        <location>
            <begin position="24"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="3">
        <location>
            <begin position="70"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="40"/>
            <end position="57"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL79222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="321" mass="33509" checksum="81ECA1BF90222C32" modified="2016-01-20" version="1">MKTFLRWLVLVGLLLGGCSPAVPTVTDAPAPPLPTQALTPYSSPTPRATLTPGWSAGTPTPFPSPTPTPRVHTVTRGQDMGGIAFLYGITIETLMDANPDVDPRVMSVGTQLLIPAAAETSTDVIPSPTPVGVLLGPLNCLRGRDEGAWCFIEVKNSQAVDVESVALVVRAANNQTGDLISQTAYSPLNRIPAGQSLPLAVSFPPPLPASVTFGVELLTALPVPADASRYLDVEMSDPQVEVEEGGKSAQVSVELRVLGGLPAREVRLAAGAYNALGEVVGLRTWQSGDPLEPGGVLPVTINVYSSGGEIETVKVWAEARP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X971</accession>
    <name>A0A0P6X971_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">30S ribosomal protein S10</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4 6" type="primary">rpsJ</name>
        <name evidence="6" type="ORF">ADN00_12605</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Involved in the binding of tRNA to the ribosomes.</text>
    </comment>
    <comment type="subunit">
        <text evidence="4">Part of the 30S ribosomal subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the universal ribosomal protein uS10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76167.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063370.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12605"/>
    <dbReference type="EnsemblBacteria" id="KPL76167">
        <property type="protein sequence ID" value="KPL76167"/>
        <property type="gene ID" value="ADN00_12605"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4002"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000049">
        <property type="term" value="F:tRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.600">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00508">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001848">
        <property type="entry name" value="Ribosomal_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018268">
        <property type="entry name" value="Ribosomal_S10_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027486">
        <property type="entry name" value="Ribosomal_S10_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036838">
        <property type="entry name" value="Ribosomal_S10_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11700">
        <property type="entry name" value="PTHR11700"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00338">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00971">
        <property type="entry name" value="RIBOSOMALS10"/>
    </dbReference>
    <dbReference type="SMART" id="SM01403">
        <property type="entry name" value="Ribosomal_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54999">
        <property type="entry name" value="SSF54999"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01049">
        <property type="entry name" value="rpsJ_bact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00361">
        <property type="entry name" value="RIBOSOMAL_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 6" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="Ribosomal_S10" evidence="5">
        <location>
            <begin position="7"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM01403"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL76167.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="102" mass="11812" checksum="279D53C93F0798D2" modified="2016-01-20" version="1">MAKQRIRIRLKAYDHRVLDQSAKRIVDTAERSGARVVGPVPLPTRIEKFTVRRSTFIDKDSHEHFEVRTHNRLIDVLDPDAKTIDMLMRLNLPAGVDIEIKI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9H0</accession>
    <name>A0A0P6X9H0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Epimerase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05645</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061995.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78725">
        <property type="protein sequence ID" value="KPL78725"/>
        <property type="gene ID" value="ADN00_05645"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001509">
        <property type="entry name" value="Epimerase_deHydtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01370">
        <property type="entry name" value="Epimerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Epimerase" evidence="1">
        <location>
            <begin position="6"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="347" mass="39107" checksum="BA6D6654FC650BC8" modified="2016-01-20" version="1">MSNRALIIGGPGTLSSSSIDYLLARGYQVGVLAQGSKFDRLPAGVTKMFGNRNQKGMLSDSISQFHPDVVIDFVCFEPEQAENAYRESRGNVGQYIFISTVDVYGYPLSRLPFREDDAWHPSTQSPYAENKRKCEEIFWKGHSTADFPLTIARPAYSFGPEFILSFMSRDLGYHMLRRIQQGRPVMVPGDGSTLMHVSSAYNTGEMIAALVGESKAMGKSYTCGHPYAITHEKYIRLFSDALSVTPEMVHIPSETILKIKHPAVAECLLPALTRYNVAFSADRFLRDFPEFKWSYTLDEWTSHVVSRVIELGLLSRGDEDIFDDELIHLWQEHEQKLINQLSNGSES</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-04-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9K8</accession>
    <name>A0A0P6X9K8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_09960</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76913.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062851.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76913">
        <property type="protein sequence ID" value="KPL76913"/>
        <property type="gene ID" value="ADN00_09960"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008984">
        <property type="entry name" value="SMAD_FHA_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49879">
        <property type="entry name" value="SSF49879"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76913.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="1857" mass="198383" checksum="08C6728891E1528F" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9P4</accession>
    <name>A0A0P6X9P4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nitroreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062886.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10140"/>
    <dbReference type="EnsemblBacteria" id="KPL76941">
        <property type="protein sequence ID" value="KPL76941"/>
        <property type="gene ID" value="ADN00_10140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.109.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029479">
        <property type="entry name" value="Nitroreductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000415">
        <property type="entry name" value="Nitroreductase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00881">
        <property type="entry name" value="Nitroreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55469">
        <property type="entry name" value="SSF55469"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nitroreductase" evidence="1">
        <location>
            <begin position="7"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="208" mass="23537" checksum="0FCF6F5A012ABD63" modified="2016-01-20" version="1">MDVYEAIAARRTIRDFAPREVSMELVKKIIAAGLQAPTNDHLRSWHFVLLQEQAQRKALLDQVIKPVGGKGALGIVNRWGLTDESQREMYVDAIPKQYSMLYNAGVLMLPCFRQPAPLLKPKDLSALNYFASIWLCIENMLLAAAAEGVFGVVRIPFESERKTMRQFVCLPDDYEIPCYLALGYPAEGARRANQVEISLEERIHLGTW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9T7</accession>
    <name>A0A0P6X9T7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_10380</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76977">
        <property type="protein sequence ID" value="KPL76977"/>
        <property type="gene ID" value="ADN00_10380"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="101" mass="11354" checksum="EEF56EFFC36C9D97" modified="2016-01-20" version="1">MLIDNSRLTAISKAVRQRLRKNLITILMYAREASRPFFGCRARSLGVFSRADSRPPLPKNRLLIGGAAPIHTLRLTSPSPENLLMVLNLQRIDMQANCPEN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XA02</accession>
    <name>A0A0P6XA02_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_16880</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064224.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16880"/>
    <dbReference type="EnsemblBacteria" id="KPL71379">
        <property type="protein sequence ID" value="KPL71379"/>
        <property type="gene ID" value="ADN00_16880"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032688">
        <property type="entry name" value="ABC2_membrane_2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12679">
        <property type="entry name" value="ABC2_membrane_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="20"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="61"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="116"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="152"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="177"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="254"/>
            <end position="273"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL71379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="278" mass="30161" checksum="AA814619163392DD" modified="2016-01-20" version="1">MAAWTITKMTLLEANRRKLIQVGLLLGFSLLAIHAAGFGLIQSQINRTDGGFSSLIGKTEFYNFLTMSGFYAVNFLTMMLVALSASNALSGEIASGSIQTMAAKPIPRRDIYVGKWLGMAILGSAYLLLMVGGMSLSVWLQTQYLPPNLLKGLLLMELNMLLVETVAIAASSALSSLASGALTFGLYGISFVGSWIEQISSYMQLQSGVDLGIITSLIFPGEAIWRRATYLMSTSLIRMVGGPFISNSTPSPAMTLYALFFLAAFFALGWRIFNRRDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XA50</accession>
    <name>A0A0P6XA50_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HTH luxR-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_16235</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72033.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064090.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16235"/>
    <dbReference type="EnsemblBacteria" id="KPL72033">
        <property type="protein sequence ID" value="KPL72033"/>
        <property type="gene ID" value="ADN00_16235"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06170">
        <property type="entry name" value="LuxR_C_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011043">
        <property type="entry name" value="Gal_Oxase/kelch_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006652">
        <property type="entry name" value="Kelch_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016032">
        <property type="entry name" value="Sig_transdc_resp-reg_C-effctor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000792">
        <property type="entry name" value="Tscrpt_reg_LuxR_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00196">
        <property type="entry name" value="GerE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01344">
        <property type="entry name" value="Kelch_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00038">
        <property type="entry name" value="HTHLUXR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00421">
        <property type="entry name" value="HTH_LUXR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00612">
        <property type="entry name" value="Kelch"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="SSF117281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46894">
        <property type="entry name" value="SSF46894"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50965">
        <property type="entry name" value="SSF50965"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00622">
        <property type="entry name" value="HTH_LUXR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50043">
        <property type="entry name" value="HTH_LUXR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH luxR-type" evidence="2">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL72033.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="439" mass="47725" checksum="329D11C807F169D9" modified="2016-01-20" version="1">MQNELPLSEREMEILRLAATGASNKEIALTLGISPNTVKVHLRNIFEKIGAASRTEAAAYAIRMGWVEMGDIPADPEEAERAAPEPVSVPQKISQTPGMRLLLIGLGILLTVMFIRRTMTPPAEINSAALTPLPPETGSEQWEALSEMPAERSGMAGVVFENRFYLLGGEGKQGLTAPTWEYTPETQTWASLADKPTPVRYAPAAVLGGQIYLAGGELADGKPVNHLESYNPREDRWESHAPLPENRSQAALAAFEGKLYLFGGWNGMAFSADVYRYDPTADQWELFASLPSARGFASAVVSGNKVLLIGGRNNTTPLDETLAFHPQWVLEGEDPWEQLAPLPQGRFAMGTVELAGNVYLVGGQSYGQVQSILTPLVLHTAENKWAALEAPPLEVGPYLGLLAYENRLHVLGGQTLMQGMTASHQTFQAIYTRLIPLIP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XA63</accession>
    <name>A0A0P6XA63_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_16365</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064114.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16365"/>
    <dbReference type="EnsemblBacteria" id="KPL72052">
        <property type="protein sequence ID" value="KPL72052"/>
        <property type="gene ID" value="ADN00_16365"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.260.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005754">
        <property type="entry name" value="Sortase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023365">
        <property type="entry name" value="Sortase_dom-sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04203">
        <property type="entry name" value="Sortase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63817">
        <property type="entry name" value="SSF63817"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01076">
        <property type="entry name" value="sortase_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132948" evidence="3">
        <location>
            <begin position="24"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="28"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="32"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL72052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="220" mass="23813" checksum="6644FCEBEB64258A" modified="2016-01-20" version="1">MAAARIILLAFLVLIFLSAAACAPPASPQTLPAPVSHVQTQQPAPTSAAAPTATSLPGPVEPEPGATFQELAQQQYGNRLIEWVEIPALNLRAPAAAMGWEAAEWQSPDALVGWASNSALPDEQTGNVILYGHNNIHSSVFRDLAELKSGDRIQLQTGEATWTYQVDAVKILSAQNEQEESEAYAAYFKQTYAPRLTLISCWPPTNNTHRVIVINYPVLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBB6</accession>
    <name>A0A0P6XBB6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_15875</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL71982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064022.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL71982">
        <property type="protein sequence ID" value="KPL71982"/>
        <property type="gene ID" value="ADN00_15875"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL71982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="80" mass="8730" checksum="4766B9EED4DA6193" modified="2016-01-20" version="1">MMIKSFLEIAPQATPTLTTTTTPETGQASYLYDGDGNLARGIVNGVVTFYPGRHYNREVDDANGTVKKFYTLGRATVAVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XBS2</accession>
    <name>A0A0P6XBS2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_02405</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the methyl-accepting chemotaxis (MCP) protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000010">
        <property type="protein sequence ID" value="KPL79667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061362.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000010.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02405"/>
    <dbReference type="EnsemblBacteria" id="KPL79667">
        <property type="protein sequence ID" value="KPL79667"/>
        <property type="gene ID" value="ADN00_02405"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003660">
        <property type="entry name" value="HAMP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004089">
        <property type="entry name" value="MCPsignal_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00672">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00015">
        <property type="entry name" value="MCPsignal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00304">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00283">
        <property type="entry name" value="MA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50111">
        <property type="entry name" value="CHEMOTAXIS_TRANSDUC_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50885">
        <property type="entry name" value="HAMP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0807">Transducer</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="15"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="201"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="domain" description="HAMP" evidence="5">
        <location>
            <begin position="271"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="Methyl-accepting transducer" evidence="4">
        <location>
            <begin position="368"/>
            <end position="625"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00029447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50885"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL79667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="691" mass="73709" checksum="762C4059CEC56BF9" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XC89</accession>
    <name>A0A0P6XC89_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_02095</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000008">
        <property type="protein sequence ID" value="KPL79932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061308.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000008.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02095"/>
    <dbReference type="EnsemblBacteria" id="KPL79932">
        <property type="protein sequence ID" value="KPL79932"/>
        <property type="gene ID" value="ADN00_02095"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006468">
        <property type="term" value="P:protein phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001638">
        <property type="entry name" value="Solute-binding_3/MltF_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00497">
        <property type="entry name" value="SBP_bac_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00062">
        <property type="entry name" value="PBPb"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="SSF56112"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="303"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="344"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="376"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="401"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="427"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="450"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="500"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="10"/>
            <end position="295"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL79932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="938" mass="105089" checksum="36074AEAD629EEF9" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XCD3</accession>
    <name>A0A0P6XCD3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Aminotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_08450</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77892.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062548.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08450"/>
    <dbReference type="EnsemblBacteria" id="KPL77892">
        <property type="protein sequence ID" value="KPL77892"/>
        <property type="gene ID" value="ADN00_08450"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.692"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009058">
        <property type="term" value="P:biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004839">
        <property type="entry name" value="Aminotransferase_I/II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00155">
        <property type="entry name" value="Aminotran_1_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Aminotran_1_2" evidence="1">
        <location>
            <begin position="56"/>
            <end position="396"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77892.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="407" mass="45387" checksum="96E1801D1FBEF430" modified="2016-01-20" version="1">METAWDHRFAQRTQRMQSSAIRELLKLVTEPDVISFAGGLPGPDVFPIKEFNQACTKVLIEEGSLALQYGTTEGYQPLREKIAEITSQYGIGVTADNILITSGSQQALDLLGKTFINPGDKILTEAPTYLGAIQAWNAYGADFVTVPSDDDGMITDALDHALRYGPKFIYVLPNFQNPSGTTLPLERRKQLVDLAERYGVPIVEDDPYGQLRYEGDHIPAVEVLDCRIRETNSCYSGNVIYLSTFSKTLAPGLRLAWVVAPPEVIRKMVLSKQGADLHTATFNQVVAYEVIKNGFLDEHIHLIRKVYRERRDAMLNSLAREMPAGVRWTHPQGGLFLWATLPEEIDTAQIFTEAIKEKVAFVPGASFFPCGGGHNTMRLNFSYSTTEQIEEGIGRLARVIRKFISIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XCX6</accession>
    <name>A0A0P6XCX6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="9">NDP-hexose 4-ketoreductase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">ADN00_01425</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80535.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061179.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01425"/>
    <dbReference type="EnsemblBacteria" id="KPL80535">
        <property type="protein sequence ID" value="KPL80535"/>
        <property type="gene ID" value="ADN00_01425"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1039"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1780.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019489">
        <property type="entry name" value="Clp_ATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036628">
        <property type="entry name" value="Clp_N_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004176">
        <property type="entry name" value="Clp_R_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001270">
        <property type="entry name" value="ClpA/B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018368">
        <property type="entry name" value="ClpA/B_CS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041546">
        <property type="entry name" value="ClpA/ClpB_AAA_lid"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07724">
        <property type="entry name" value="AAA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17871">
        <property type="entry name" value="AAA_lid_9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02861">
        <property type="entry name" value="Clp_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10431">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00300">
        <property type="entry name" value="CLPPROTEASEA"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01086">
        <property type="entry name" value="ClpB_D2-small"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81923">
        <property type="entry name" value="SSF81923"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51903">
        <property type="entry name" value="CLP_R"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00870">
        <property type="entry name" value="CLPAB_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="6" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 5" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Clp R" evidence="8">
        <location>
            <begin position="4"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="127"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="424"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="6">
        <location>
            <begin position="733"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="141"/>
            <end position="158"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51903"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL80535.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="832" mass="93446" checksum="CCB14BA77540650F" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XD49</accession>
    <name>A0A0P6XD49_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peripla_BP_6 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_01170</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000003">
        <property type="protein sequence ID" value="KPL80831.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01170"/>
    <dbReference type="EnsemblBacteria" id="KPL80831">
        <property type="protein sequence ID" value="KPL80831"/>
        <property type="gene ID" value="ADN00_01170"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1979"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028081">
        <property type="entry name" value="Leu-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13458">
        <property type="entry name" value="Peripla_BP_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132990" description="Peripla_BP_6 domain-containing protein" evidence="2">
        <location>
            <begin position="51"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="domain" description="Peripla_BP_6" evidence="3">
        <location>
            <begin position="107"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="55"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF13458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL80831.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="462" mass="47837" checksum="C31ECDD23E6A38AB" modified="2016-01-20" version="1">MCVLSTNPWLNKMPKFQIFHLGEKKMKFSKFFYVVVLLAMVLAACTPAQPATEAPAAEAPAATEAPAATEAPAATEAPAAEAPAAAGEPEVCTTDAYGCAVIPSGTTIKIGMGGPMIGDYSMFGIDISQGTMVALSEHEGLNGSAYELVALDTGGAPEAGAAVANKLVTDPTVVAIAGHIFSGETDAAMPIYEKAGLPMLSPSATNPPLTQQGNKSFNRIAFTDATQAKYAADMLFTDMGFTKIATIHDGSTYGKGLADEVAKVFTELGGEVVASEAINPGEADYSSTLSAIASKGPEAVYFGGYAAEAIVMVNQWNQAGLTGVQFFGCDGTYGVEFTDKTGPNGEGAIAVSLVPPDSPEKTAFDTKYKEMFGLEAGELSPFTWSAYDVGSALVYAIESVAVVSDDGNTYIPRGALMDAVRGLKDFTGLTGLISCDEVGECNASGPTFYSVQDGKWAPYSAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDU8</accession>
    <name>A0A0P6XDU8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">LMWPc domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_00780</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the low molecular weight phosphotyrosine protein phosphatase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061043.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00780"/>
    <dbReference type="EnsemblBacteria" id="KPL81093">
        <property type="protein sequence ID" value="KPL81093"/>
        <property type="gene ID" value="ADN00_00780"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3554"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004725">
        <property type="term" value="F:protein tyrosine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006470">
        <property type="term" value="P:protein dephosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023485">
        <property type="entry name" value="Ptyr_pPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036196">
        <property type="entry name" value="Ptyr_pPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017867">
        <property type="entry name" value="Tyr_phospatase_low_mol_wt"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01451">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00719">
        <property type="entry name" value="LMWPTPASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00226">
        <property type="entry name" value="LMWPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52788">
        <property type="entry name" value="SSF52788"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LMWPc" evidence="3">
        <location>
            <begin position="6"/>
            <end position="149"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011063"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00226"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL81093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="156" mass="17375" checksum="7D7781079F598EFB" modified="2016-01-20" version="1">MENPKIKVVFVCLGNICRSPMAEAVFKSLVKEASLEEQFEISSGGTGGWHTGERPHSGTQAVLKLNQVYLDPQKRAQQVNSVALRQADYVVALDQENAAALKRLGVESRLLLSYCDNGHPLDVPDPYYEQNFDVVYDLVRDGCQCLLNEIRARHGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XF51</accession>
    <name>A0A0P6XF51_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_06345</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78833.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78833">
        <property type="protein sequence ID" value="KPL78833"/>
        <property type="gene ID" value="ADN00_06345"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78833.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="77" mass="9105" checksum="A7BDAA6B02EF52D1" modified="2016-01-20" version="1">MSNLFLDNLFKVEFDSIYDNPLPAHQRMLHHSHIKQAYAAIYPFGSNMRHKPFAVDRITLDIFCSEPGEHFRLFVRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XFJ3</accession>
    <name>A0A0P6XFJ3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_14725</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000035">
        <property type="protein sequence ID" value="KPL73591.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063792.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000035.1"/>
    </dbReference>
    <dbReference type="REBASE" id="132876">
        <property type="entry name" value="OapP3M1ORF14730P"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL73591">
        <property type="protein sequence ID" value="KPL73591"/>
        <property type="gene ID" value="ADN00_14725"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2111"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009036">
        <property type="term" value="F:type II site-specific deoxyribonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10010">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015105">
        <property type="entry name" value="NgoMIV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037083">
        <property type="entry name" value="NgoMIV_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011335">
        <property type="entry name" value="Restrct_endonuc-II-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09015">
        <property type="entry name" value="NgoMIV_restric"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52980">
        <property type="entry name" value="SSF52980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL73591.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="286" mass="32586" checksum="A68A1E48B53AB361" modified="2016-01-20" version="1">MLMENLRKEYHKKIGEQIIRIYERKGQVFANFADGDSKISTMISLGILDQMEFTPKRERISEQSVGDIFEVVTKEYLESSFELLGRIRPGKWLYQTAQTSISNFDQYEHLQYLKKLVSENQALKSAIGGDYIVRPDIVISRIPISLDELNCEKDILDNQLAIASHSPLLAKPDLRRAPILHASISCKWTLRSDRAQGTRTEALNLIRNRKGNQPHIVAVTAEPLPNRIATLALGTGDIDCVYHFALYELVKAIQLTDRDDLSEFIQTMIEGKRLRDISDLPFDLAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XFT5</accession>
    <name>A0A0P6XFT5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MFS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_03920</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061658.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79044">
        <property type="protein sequence ID" value="KPL79044"/>
        <property type="gene ID" value="ADN00_03920"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011701">
        <property type="entry name" value="MFS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044770">
        <property type="entry name" value="MFS_spinster-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23505">
        <property type="entry name" value="PTHR23505"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07690">
        <property type="entry name" value="MFS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="78"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="103"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="135"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="163"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="225"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="268"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="302"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="329"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="368"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="397"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="12"/>
            <end position="425"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL79044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="460" mass="49901" checksum="321754E6D9D155AA" modified="2016-01-20" version="1">MKPGQTRHSGKTLFALGLGYLIDQGEAQAMGVLSPIIQSLWGVSYGMLGLMTTLRNIAQTVSAPLWGYAADRYSRKKVLIFGTGIWGIWTILVGLMPNFTGVLIIRAISGLGLGCLMPATFSLIADHFPQERRGFALGVIGFVGLMGTVVGVLALGFVATPELWRWGFVGLGVFSILSGVVIWLFVEEPPRGAAEPELAGLIDHENEQRYMINWKDVFSTLRIPTIWAAILQGVTGTMPWVVMGFYFINWMVTDLNFSNQISFTDPAGSAPLVFAVVVVGAAISNFMGGLIGDYAEKISPKYGRTVIGQFSVLSGVPLMYILLTRAQTMTFPQLLGLTMFTALMIGWPGRGAKEPMMQAVVPPEIRSSAYSVVNLIEGGLSAFAGLIAGALADRIGLTYALVWTIPFPWLICGIFFTLFYFTYPKDAAKVKNLMGQRREDLLKLKQETGAVAGLEAAEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XG50</accession>
    <name>A0A0P6XG50_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_18410</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064514.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70036">
        <property type="protein sequence ID" value="KPL70036"/>
        <property type="gene ID" value="ADN00_18410"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="65" mass="6653" checksum="A53F37A6F108F342" modified="2016-01-20" version="1">MEQNDKTRTLVLGALAGALVGLAAAMILINDAEKKNDKPHLSAGDGVKVGLGLLGVLRLLTDSGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGE3</accession>
    <name>A0A0P6XGE3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Glyco_tran_28_C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05995</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78782.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062061.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05995"/>
    <dbReference type="EnsemblBacteria" id="KPL78782">
        <property type="protein sequence ID" value="KPL78782"/>
        <property type="gene ID" value="ADN00_05995"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016758">
        <property type="term" value="F:hexosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007235">
        <property type="entry name" value="Glyco_trans_28_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04101">
        <property type="entry name" value="Glyco_tran_28_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Glyco_tran_28_C" evidence="1">
        <location>
            <begin position="279"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04101"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78782.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="403" mass="44246" checksum="6161A9CEB879277D" modified="2016-01-20" version="1">MKMLIPLFSPATGTWGGLTRVMAIAEAAKAGGHEVAFCASGYLEQTLRGRGFAVFSTPIPTLLGLPAPISRRIEKRSQSVTLPVPPGRSIGSIWLVLMISGMAHGKFLLRVVEAEQKAADQFKPDFLFTDLDPGAYLLAKLTGLPIASAYQSPMKHGINTLAWKRMNVAVNQVLTAKGFSEQRVEELFFGKHCLKIIPSIPELEDEDVNRPDVRFVGQLLAAIHPKEAREFIPEAGKRYIFVYMGTGSVSVDRVRDALSRCLPEDGPLRAIVGAQSVTEVERLGAVELRPYVSAQALLPFCDWTLCHGGQNTIIESLIHGVPLIVFPGPIFERRYNAQQIHRLGAGVMGEVNQFTPSWIQDLFPQRDRMAIKALELGEKIKSYGGAKVAIEAMEIWGKTMPST</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGJ3</accession>
    <name>A0A0P6XGJ3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">MFS transporter</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_06420</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78846.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062134.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06420"/>
    <dbReference type="EnsemblBacteria" id="KPL78846">
        <property type="protein sequence ID" value="KPL78846"/>
        <property type="gene ID" value="ADN00_06420"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020846">
        <property type="entry name" value="MFS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010290">
        <property type="entry name" value="TM_effector"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05977">
        <property type="entry name" value="MFS_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="SSF103473"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50850">
        <property type="entry name" value="MFS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="26"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="56"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="88"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="116"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="153"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="184"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="231"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="270"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="304"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="357"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="386"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="domain" description="MFS" evidence="6">
        <location>
            <begin position="23"/>
            <end position="410"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL78846.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="413" mass="44587" checksum="CEAD7FF5DBEEC0A4" modified="2016-01-20" version="1">MTPLAQRFSPFFSTTFAAFRHRNYRLWFYGQLVSLVGTWMQSAAQGYLVYELTGSAAYLGYVGFVSGLPSWLLILYGGVIADRVSRRTLLIITQTVMMALAFVLAALVFLGVVQPWHILVLAFLLGVANAFDAPARQSFIVELVEREDLTNAIALNSTMFNTGAIVGPAFAGLVYALTGPAWCFSINGISFIAVIFALGLMKMPPKPAPVNRSSAMRAIVEGVGYIRSEPLVFTLILTVFVLNVFGFGLITLVPAWAVTILHGDATTNGLLLSARGVGAVICGLLIASLSGSRFRGRMWSINSFILPLALAGFALSTWLPLSLVFMAVTGFALIAVLNNSNAMVQSRVPDDLRGRVMGIYSLMLLGGGPVGSLLVGVMAEHTSEQIAAYACAGILFLFSVWIWFFRPNVRQMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGX9</accession>
    <name>A0A0P6XGX9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Lipoyl-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_03825</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79029.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061641.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03825"/>
    <dbReference type="EnsemblBacteria" id="KPL79029">
        <property type="protein sequence ID" value="KPL79029"/>
        <property type="gene ID" value="ADN00_03825"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000089">
        <property type="entry name" value="Biotin_lipoyl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011053">
        <property type="entry name" value="Single_hybrid_motif"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00364">
        <property type="entry name" value="Biotin_lipoyl"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51230">
        <property type="entry name" value="SSF51230"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lipoyl-binding" evidence="1">
        <location>
            <begin position="18"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79029.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="85" mass="9317" checksum="BB5D0A06ACCE6925" modified="2016-01-20" version="1">MDENVILVLMPKKDLVKASAVLTRWLVKDGEWIEAGQAFFAYESEKVESEATAPASGFARLLVEAGSKVRINEPVAEIHGGSREE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XH50</accession>
    <name>A0A0P6XH50_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_04475</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061756.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04475"/>
    <dbReference type="EnsemblBacteria" id="KPL79120">
        <property type="protein sequence ID" value="KPL79120"/>
        <property type="gene ID" value="ADN00_04475"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13247">
        <property type="entry name" value="Fer4_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="1">
        <location>
            <begin position="9"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="1">
        <location>
            <begin position="49"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="1">
        <location>
            <begin position="82"/>
            <end position="111"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="163" mass="17836" checksum="CF975ADE3252D3E3" modified="2016-01-20" version="1">MTTSSSKFKFITCDPELCVGCQLCEYICSYTKTGEFNTYHSRIRTVRAEEILITAVACRTCEDAPCVIACPRDALIQDKDTGIIHVDNSKCDGCAWCVVACDFGAISIDPASKLAEICDQCEDVEGGPQCVIWCPKEALELVTADQLAQKARRKLAVKEVLGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XHD8</accession>
    <name>A0A0P6XHD8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_05110</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061876.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79221">
        <property type="protein sequence ID" value="KPL79221"/>
        <property type="gene ID" value="ADN00_05110"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133068" evidence="2">
        <location>
            <begin position="26"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="372"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="381"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="406"/>
            <end position="422"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="543" mass="59792" checksum="04F19B8FE8E9A48D" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XHF3</accession>
    <name>A0A0P6XHF3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Dehydrogenase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_04220</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061890.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79239">
        <property type="protein sequence ID" value="KPL79239"/>
        <property type="gene ID" value="ADN00_04220"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004104">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000683">
        <property type="entry name" value="Gfo/Idh/MocA-like_OxRdtase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01408">
        <property type="entry name" value="GFO_IDH_MocA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02894">
        <property type="entry name" value="GFO_IDH_MocA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GFO_IDH_MocA" evidence="1">
        <location>
            <begin position="5"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="domain" description="GFO_IDH_MocA_C" evidence="2">
        <location>
            <begin position="135"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01408"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF02894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="385" mass="42508" checksum="91240B0F83E149C5" modified="2016-01-20" version="1">MKKNFKVGVVGLGFIGPAHIEGVRRLGDVVVGIVGKDLQEAQTAAEALHVEKAYATFDEMIADPEIEIVHVCSPNYLHYSHTVKALEAGKHVICEKPLTVTAEESKALVELAKTKQLACSVNYNLRYYPVNHEAREIVQKGELGKIHNIHGAYLQDWLLYPTDWNWRLLPKEGGALCSVADIGSHWIDMVMFVTGLRVSEVMADLGTSIPVRKRPLGEVETFAGKMTKKEMAYEEVHVTGDDFANILFRFDNGAKGSLAVSQVSAGRKNSLSYEIDGSASALAWNSESPDALWRGYRGRYNEVLIKDPSLMNPAAQSVASYPGGHTEGFPDTFKQLAKKVNQYILKGDFSAKPDFPTFEDGHRALVIEEAILESSQTGKWVKISE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XIH9</accession>
    <name>A0A0P6XIH9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CRISPR_Cas6 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_13020</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000028">
        <property type="protein sequence ID" value="KPL75307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063457.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000028.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13020"/>
    <dbReference type="EnsemblBacteria" id="KPL75307">
        <property type="protein sequence ID" value="KPL75307"/>
        <property type="gene ID" value="ADN00_13020"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019267">
        <property type="entry name" value="CRISPR-assoc_Cas6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045747">
        <property type="entry name" value="CRISPR-assoc_prot_Cas6_N_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10040">
        <property type="entry name" value="CRISPR_Cas6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRISPR_Cas6" evidence="1">
        <location>
            <begin position="164"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF10040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL75307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="285" mass="32401" checksum="D5E9D5A5DCEC9A72" modified="2016-01-20" version="1">MKDHPLPFPEKQESLLASVVIHLESLNAGSLLPETGRKVHGFWHEHWKRICPPAAESLHPNNGKAEFTLSPIFGLPQPENDVIRLSPGMPAWFRVTTLRPTLTEALFNEHNGWLITLPAELDFGPIRWKPSFQPFSKIDAAWSWLCSYEAMRRAAQPSVSWKISLSTPTSFSGRYVDFTFPLPELLVKSWLERWNHFAPPALGLPEELIDAAREHLRVTEYHLSTCPGERQTIGCRGSLVIQAYHLPPEARTQLDLLFLYAYYCGSGHRTAQGMGQTRLLRRWSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XIW6</accession>
    <name>A0A0P6XIW6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">DNA-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_12855</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000027">
        <property type="protein sequence ID" value="KPL75526.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063446.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000027.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_12855"/>
    <dbReference type="EnsemblBacteria" id="KPL75526">
        <property type="protein sequence ID" value="KPL75526"/>
        <property type="gene ID" value="ADN00_12855"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041657">
        <property type="entry name" value="HTH_17"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010093">
        <property type="entry name" value="SinI_DNA-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12728">
        <property type="entry name" value="HTH_17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01764">
        <property type="entry name" value="excise"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH_17" evidence="1">
        <location>
            <begin position="8"/>
            <end position="56"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF12728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL75526.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="66" mass="7974" checksum="635B279890E3C087" modified="2016-01-20" version="1">MERKPPEFLTIEEVSEYLRVPLSSLYKLAQQGKIPASKVGRHWRFRREFIDRWVNDQIQTKVTQSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-12-02" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKF5</accession>
    <name>A0A0P6XKF5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10955</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76486.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76486">
        <property type="protein sequence ID" value="KPL76486"/>
        <property type="gene ID" value="ADN00_10955"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76486.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="131" mass="14327" checksum="6FD948C0A8CC36A3" modified="2016-01-20" version="1">MLPQLMDSLKITAIGMGLVFIAILVLWGLMELLVQVTVRRVKAEIAPRENELETGGAAPSLPDANLQTRQRAAAAAVATALALQDAKSDHKPIRVLPAPKEQASAWQTLMRASHLNQRSSLFTRKPRGRVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKH4</accession>
    <name>A0A0P6XKH4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ABC transmembrane type-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_16000</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cell membrane</location>
            <topology evidence="5">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72001.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064044.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16000"/>
    <dbReference type="EnsemblBacteria" id="KPL72001">
        <property type="protein sequence ID" value="KPL72001"/>
        <property type="gene ID" value="ADN00_16000"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3634"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045621">
        <property type="entry name" value="BPD_transp_1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19300">
        <property type="entry name" value="BPD_transp_1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="9"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="100"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="135"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="244"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="287"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="6">
        <location>
            <begin position="96"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL72001.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="315" mass="34794" checksum="3E782DC6DC0C118B" modified="2016-01-20" version="1">MFRYLARRALALLPVFFLMTIIVFLLIRLVPGDPVDVMYGGEGLSEEQRAALETQLGIDQPLALQYLRWLGRALTGDLGRSYKAQMPVLDLILQRLPATLYLSVAALLFSVIIAIPLGILSAVKRNTWIDLSAMIFAIFGISLPQFWSGILLVLIFAVGLRWLPSINYVPPTDNFGLFLRHLLLPAVTLGWSLAGTTTRLTRSSILEELGKDYVRTARSKGMREHAVLWGHVLRNALIPTVTMIGLQMAFLIGGAVVVESVFAWPGIGLLVVDSIFGRDYPVVQGVILTVAVLVVVVSLIVDVIYTVLDPRIRFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKH7</accession>
    <name>A0A0P6XKH7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_11240</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76532.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063108.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76532">
        <property type="protein sequence ID" value="KPL76532"/>
        <property type="gene ID" value="ADN00_11240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133106" evidence="2">
        <location>
            <begin position="30"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="67"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="69"/>
            <end position="104"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL76532.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="354" mass="39348" checksum="F65886637BF24C3B" modified="2016-01-20" version="1">MQRLNHSSLKVVLAALLVIMLACNMPGSASTPAATLNETQVALSIQSTMLAEESAQATANAVVQVLPTQPPAPTTPPEQPTYTPYPTFTPQPAATEPPAPTAADPQPAAAAELTDEQIKEKIRSANVLVFEDMRGNFDRKPIVHDVINRMRFSGGKVVEVGDALGKFKDQLLSTTQWDLIIVAAEDHDAVQGEFWEYMQDHVNNGAAVIIEMWYMNQHYSDIQPMLSQCGVEYHKDWYRDIFSDPLDYSIYWLDPSSPILTEPNSGMSLSNVSYLYWTFDAGDLLRLSTGGDAQLVAGIYPREKSQYGVLATCMEGRMIIQTFCSHDYNPSHVMSLWENYIVYTLTNHFKTTGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XKI2</accession>
    <name>A0A0P6XKI2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_01370</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80525.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061168.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80525">
        <property type="protein sequence ID" value="KPL80525"/>
        <property type="gene ID" value="ADN00_01370"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1026"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.160.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002838">
        <property type="entry name" value="AIM24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036983">
        <property type="entry name" value="AIM24_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016031">
        <property type="entry name" value="Trp_RNA-bd_attenuator-like_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01987">
        <property type="entry name" value="AIM24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51219">
        <property type="entry name" value="SSF51219"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00266">
        <property type="entry name" value="TIGR00266"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL80525.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="226" mass="24442" checksum="1619034A1FE8E843" modified="2016-01-20" version="1">MQYKIDGTVLQALEVHLTQGEAMFTESGGMSWMSDGIEMATNTRGGLMAGLGRALAGESLFMTTYTCTAPQAFMVFTPEAPGKVIDIKLEAGQSLIAQKDAFMCAENTVQMEMHFRKKLGAGFFGGEGFILQKVTGPGTVFFEIPGEVKGYTLKAGQRIKVDPGHIAMFEPTVQYDIQMVKGITNIMFSGEGLFLATLTGPGRVWMQTMPIANLASKIARYIPSKG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XLD6</accession>
    <name>A0A0P6XLD6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">ATPase AAA</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_00845</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061054.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00845"/>
    <dbReference type="EnsemblBacteria" id="KPL81104">
        <property type="protein sequence ID" value="KPL81104"/>
        <property type="gene ID" value="ADN00_00845"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3567"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AAA" evidence="1">
        <location>
            <begin position="261"/>
            <end position="394"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL81104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="510" mass="57044" checksum="164DA7CFBAB7E77A" modified="2016-01-20" version="1">MIFTEQLDLYLKARFTLIILVSSEEERAIQAIRALCDKTGRGCQSWDTADGFQWIAKTSGSVPVAKDPLAALEKIEAADENHCSLFILKDFHEVWSNPIIKRKLRSLSQKLKYTRKSILITTPAGIIPEELKNESVLVEFPLPNSQEMEQVLLDLTQPAGIKINLTDLGREKLVQAALGLTAAQAQRVFARAIVRSGSLDDRDIELVTEEKKQIIRESEALEFYAVSETPDDVGGLGVLKDWLRLRERAFTAEARKYGLPSPKGIALIGIPGTGKSLTAKMIGGLWRLPLLRLDVGSLFGSLVGESEERARRALQLAETVAPCILWIDEIEKALAHGGLDSGTSTRVFGTILTWMQEKTSPVFVVATANDISSIPPELLRKGRFDEIFFLDLPTLEERKEIISVHLRKRSRQPQDYNLEELAQKCAGYVGAEIEQAIIDAMYLGFNDQQREFTSADILTSFHKQVPLSISQREKVEALRNWLREGRAQSASFREAQEAADQFVRIQLDLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XLW5</accession>
    <name>A0A0P6XLW5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_01135</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000003">
        <property type="protein sequence ID" value="KPL80827.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061127.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000003.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01135"/>
    <dbReference type="EnsemblBacteria" id="KPL80827">
        <property type="protein sequence ID" value="KPL80827"/>
        <property type="gene ID" value="ADN00_01135"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1972"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000866">
        <property type="entry name" value="AhpC/TSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024706">
        <property type="entry name" value="Peroxiredoxin_AhpC-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00578">
        <property type="entry name" value="AhpC-TSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000239">
        <property type="entry name" value="AHPC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="SSF52833"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="1" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="4">
        <location>
            <begin position="3"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate" evidence="3">
        <location>
            <position position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR000239-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL80827.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="153" mass="17401" checksum="981DFFC94B189B16" modified="2016-01-20" version="1">MPIANQISAPDFELADEAGKLHRLSDYRGKPVLLYFYPKDDTSGCTTEACNFRDDYSAYEEAGVTILGVSPDDTDSHAKFKQKYALPFSLLADVDHKVCELYDVWKLKKMYGREYFGVERTTFLINAEGMIVKVFEKVKPADHSKEVLEALKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XM79</accession>
    <name>A0A0P6XM79_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glycosyl transferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_18310</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064494.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18310"/>
    <dbReference type="EnsemblBacteria" id="KPL70019">
        <property type="protein sequence ID" value="KPL70019"/>
        <property type="gene ID" value="ADN00_18310"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028098">
        <property type="entry name" value="Glyco_trans_4-like_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13439">
        <property type="entry name" value="Glyco_transf_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glyco_trans_4-like_N" evidence="1">
        <location>
            <begin position="16"/>
            <end position="201"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13439"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="406" mass="45334" checksum="C6E0DFDED0AC37D6" modified="2016-01-20" version="1">MHILLIHQAFASLKEGGGTRHIELSQFLVQRGHRVTIITSPVSYLTGKSRLQKNRWIEKEQFLPGIEIIRAYTYPALHRSFFHRLINFFSFMISSFLAGLNISGVDLVWGTTPPIFQSVTAWLLARLKGRPFLLEIRDLWPKFAVDLGVIKNPLLIRASLWLEKFLYHRADQLIVNSPGYVDHVRERGGKNVSLIPNGVDPAMFDPAETGQTFRQELGLEDRFIILYAGAHGLANNLDMVLEAADELRDEPRICFMMVGDGKEKAHLVETAQQMDLPNIVFLPAMPKEKMAQVMGAADACLASLQPIESFKTTYPNKVFDYMAAGRPVLLAIDGVIRQVVDAAAAGVFVQPGSPSALAQAVRQLYADPAAAKQMGLSGRQYVEKHFDRASLADQLAQLLELMRKKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XME0</accession>
    <name>A0A0P6XME0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_14920</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the IMPACT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000036">
        <property type="protein sequence ID" value="KPL73080.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063831.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000036.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14920"/>
    <dbReference type="EnsemblBacteria" id="KPL73080">
        <property type="protein sequence ID" value="KPL73080"/>
        <property type="gene ID" value="ADN00_14920"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1847"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023582">
        <property type="entry name" value="Impact"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001498">
        <property type="entry name" value="Impact_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036956">
        <property type="entry name" value="Impact_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_S5_D2-typ_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015269">
        <property type="entry name" value="UPF0029_Impact_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020569">
        <property type="entry name" value="UPF0029_Impact_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16301">
        <property type="entry name" value="PTHR16301"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09186">
        <property type="entry name" value="DUF1949"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01205">
        <property type="entry name" value="UPF0029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="SSF54211"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="SSF54980"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00910">
        <property type="entry name" value="UPF0029"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UPF0029" evidence="2">
        <location>
            <begin position="22"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="domain" description="DUF1949" evidence="3">
        <location>
            <begin position="144"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007665"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01205"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF09186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL73080.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="218" mass="23412" checksum="94A9A47BBCF3C0DD" modified="2016-01-20" version="1">MSEKKPYLLPAGPARTEIRVVNSRFIASAGPARTVEEARAFIEAARAEFADATHNVPGFVIGYPPSVITHYSDDGEPSGTAGRPVLAVLQGSGLGDVVVVITRYFGGTKLGTGGLVRAYTEATQEVLRILPRAHRILTHSVMLAIPYSYLERVRLLAPAHQGLILDEDFGADVTLSLRFPIEALEGFQTALGELTRGSVLAEIIEANTETLMPVDQSD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XMY8</accession>
    <name>A0A0P6XMY8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Amino acid permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_11460</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76590.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11460"/>
    <dbReference type="EnsemblBacteria" id="KPL76590">
        <property type="protein sequence ID" value="KPL76590"/>
        <property type="gene ID" value="ADN00_11460"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.993"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002293">
        <property type="entry name" value="AA/rel_permease1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13520">
        <property type="entry name" value="AA_permease_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="33"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="80"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="111"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="145"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="182"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="221"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="262"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="319"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="346"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="391"/>
            <end position="414"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="420"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL76590.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="453" mass="49188" checksum="197F1CC382125144" modified="2016-01-20" version="1">MRGLDMTLFTVCAILVMDTLAPSASIGPASISWWLITLVLFFIPYGLITAELGTTYPDQGGLYIWVKKAFGEKWAARTTWLYWINVALWMPSVYVLFAGMFAQLFAPEMGLWGQIAIGVVMTWITVGIGIMSLETSKWVPNIGAIFKALIMVVIGVAAFIFAGKNGVANDLSFSSILPTWDAGLFFLPVIVYNFMGFELMSGAGDEMENPGRDIPKAIITAGLLITVFYLLGTVGMLMAVPVEDLGLVEGIIDTLRVLLGESQAANIAVTVLGIGALYSFLANMVTWTMGANRTAAEAASDNELPQIFGKLHAQYKTPVSAFIITGVVSTVVIVLYGFMAGSAEDLFWTLFAFSSMVFLMPYLALFPAFLKLRKTDPHAERPYRVPGGHTFASILVVICEIFIIQGIVFFIWVPGEPIDWAFAAPVLIGVALTLIVGEVLLNVAAKEKKLNGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XNR5</accession>
    <name>A0A0P6XNR5_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ribosomal RNA small subunit methyltransferase G</fullName>
            <ecNumber evidence="2">2.1.1.-</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="2">16S rRNA 7-methylguanosine methyltransferase</fullName>
            <shortName evidence="2">16S rRNA m7G methyltransferase</shortName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="2" type="primary">rsmG</name>
        <name evidence="3" type="ORF">ADN00_06935</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Specifically methylates the N7 position of a guanine in 16S rRNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="2"/>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78214.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062256.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06935"/>
    <dbReference type="EnsemblBacteria" id="KPL78214">
        <property type="protein sequence ID" value="KPL78214"/>
        <property type="gene ID" value="ADN00_06935"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3203"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070043">
        <property type="term" value="F:rRNA (guanine-N7-)-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00074">
        <property type="entry name" value="16SrRNA_methyltr_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003682">
        <property type="entry name" value="rRNA_ssu_MeTfrase_G"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31760">
        <property type="entry name" value="PTHR31760"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02527">
        <property type="entry name" value="GidB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF003078">
        <property type="entry name" value="GidB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00138">
        <property type="entry name" value="rsmG_gidB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="2" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="S-adenosyl-L-methionine binding" evidence="2">
        <location>
            <begin position="130"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="79"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="84"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="149"/>
        </location>
        <ligand>
            <name>S-adenosyl-L-methionine</name>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00074"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78214.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="239" mass="26327" checksum="3B37173C25A934D9" modified="2016-01-20" version="1">MMENFRKNIKDLLGVQLSDSQVQAFITYEEQLLEYNAQFNLTAIRDSEGIRLKHFIDSLSCLLALREKPVPPSRLVDIGTGAGFPGIPLKILFPAMQLTLVESVGKKARFCEHMARALKLENVLVLQSRAEELGQDPAHREKYDWAVARAVAQLPILAEYLLPLVRVGGGMIAQKGESGPAETQSAQNAIHILGGRLHKLIPVQISGVAEDRYLVVVDKVAATPKHLPRRVGIPSKSPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XNU2</accession>
    <name>A0A0P6XNU2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09995</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76919.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062858.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76919">
        <property type="protein sequence ID" value="KPL76919"/>
        <property type="gene ID" value="ADN00_09995"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="37"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="60"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="118"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="153"/>
            <end position="172"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76919.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="179" mass="20122" checksum="AC52D3F181AE0E35" modified="2016-01-20" version="1">MEEDPQESISEQPLPGRMAEYGTLRDEILRRMEMRNSIVFGTLTFTGALLGFGLETPALALLYPIIAMFLAAAWVQNDTVISNLGRYIRENLEDAQTGLRWETERQKNRLREAQSGKIYPSAIFSSEGVFLITQGMALLIGFANQPRFTILEWGLSAAAVICILLTIAFFHYSSINNIR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XP13</accession>
    <name>A0A0P6XP13_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Zn-dependent protease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_07255</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062424.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07255"/>
    <dbReference type="EnsemblBacteria" id="KPL78351">
        <property type="protein sequence ID" value="KPL78351"/>
        <property type="gene ID" value="ADN00_07255"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3271"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008233">
        <property type="term" value="F:peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.20.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010430">
        <property type="entry name" value="DUF1028"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029055">
        <property type="entry name" value="Ntn_hydrolases_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_repeat"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06267">
        <property type="entry name" value="DUF1028"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="SSF48452"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56235">
        <property type="entry name" value="SSF56235"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="224"/>
            <end position="257"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="323" mass="35223" checksum="FEFA854E3EA54709" modified="2016-01-20" version="1">MNNRKSGSPSPAYPRFPFAHTFSIVARDPETGEMGAAVQSHWFSTGSLVIWAEAGVGAVATQAMVDPSYGPLGLELMFTGISAPTALANLLAQDVRKEIRQVAMVDARGRVGAHTGIQCIAEAGHVTGDGFSVQANMMLNNTVWHAMAEAFRASTGRLADRMILALQAAQEAGGDIRGQQSAAMIVVKAQSSSKPWNDTLIDLRVEDHPRPIEELQRLLTVQDAYEWMNKGDEFMARNEVDKALSAYQKANSMAPHLIELPFWNAVTLADMDRVEEALPLFEQVFNADPNWAELLKRLPPAGLLKDDPIMLARILSVLSKNTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XPY0</accession>
    <name>A0A0P6XPY0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Transcriptional regulator</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_09350</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062726.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09350"/>
    <dbReference type="EnsemblBacteria" id="KPL77321">
        <property type="protein sequence ID" value="KPL77321"/>
        <property type="gene ID" value="ADN00_09350"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000160">
        <property type="term" value="P:phosphorelay signal transduction system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00383">
        <property type="entry name" value="trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001867">
        <property type="entry name" value="OmpR/PhoB-type_DNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039420">
        <property type="entry name" value="WalR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48111">
        <property type="entry name" value="PTHR48111"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00486">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00862">
        <property type="entry name" value="Trans_reg_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="SSF52172"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51755">
        <property type="entry name" value="OMPR_PHOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Response regulatory" evidence="3">
        <location>
            <begin position="4"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="domain" description="OmpR/PhoB-type" evidence="4">
        <location>
            <begin position="127"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="DNA-binding region" description="OmpR/PhoB-type" evidence="2">
        <location>
            <begin position="127"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="1">
        <location>
            <position position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51755"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL77321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="229" mass="26242" checksum="68E553F575BFF3F6" modified="2016-01-20" version="1">MSSTILVVDDKSSVRQLLREYLAEQGYRIVEADNGENALYTARHVKPDLILLDIMMPKMDGYEFIRQYRKEARTPVIIITARQEETDAVLGLELGADDYVVKPFRMRELLARIHSVFRRSEAAPEQEECLQHAGLRMNLTTHEVSLNDRPVSLTPIEFDLLASLMKSPGRVFTRSQLVDSLFESGFTGLERTLNVHIRNLRKKIEPNPAEPQYIESVFGVGYRFSKEIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="30" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQV9</accession>
    <name>A0A0P6XQV9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">FtsK domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">ADN00_04935</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="13 14" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="13 14">P3M-1</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="8">Homohexamer. Forms a ring that surrounds DNA.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the FtsK/SpoIIIE/SftA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04935"/>
    <dbReference type="EnsemblBacteria" id="KPL79192">
        <property type="protein sequence ID" value="KPL79192"/>
        <property type="gene ID" value="ADN00_04935"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.354"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025199">
        <property type="entry name" value="FtsK_4TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041027">
        <property type="entry name" value="FtsK_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002543">
        <property type="entry name" value="FtsK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018541">
        <property type="entry name" value="Ftsk_gamma"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13491">
        <property type="entry name" value="FtsK_4TM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17854">
        <property type="entry name" value="FtsK_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09397">
        <property type="entry name" value="FtsK_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01580">
        <property type="entry name" value="FtsK_SpoIIIE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00843">
        <property type="entry name" value="Ftsk_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50901">
        <property type="entry name" value="FTSK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="6" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7 11" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="55"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="88"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="11">
        <location>
            <begin position="177"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="domain" description="FtsK" evidence="12">
        <location>
            <begin position="450"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="223"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="256"/>
            <end position="274"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <begin position="467"/>
            <end position="474"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00025923"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KPL79192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="800" mass="86249" checksum="DCA9A117AA1B2EAD" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XQY6</accession>
    <name>A0A0P6XQY6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_03880</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="4">Cell membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the binding-protein-dependent transport system permease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03880"/>
    <dbReference type="EnsemblBacteria" id="KPL79229">
        <property type="protein sequence ID" value="KPL79229"/>
        <property type="gene ID" value="ADN00_03880"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06261">
        <property type="entry name" value="TM_PBP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.3720.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000515">
        <property type="entry name" value="MetI-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035906">
        <property type="entry name" value="MetI-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00528">
        <property type="entry name" value="BPD_transp_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF161098">
        <property type="entry name" value="SSF161098"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50928">
        <property type="entry name" value="ABC_TM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 4" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="122"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="160"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="194"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="234"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="295"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transmembrane type-1" evidence="5">
        <location>
            <begin position="123"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU363032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50928"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL79229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="329" mass="37424" checksum="731A88646705A771" modified="2016-01-20" version="1">MLLLGYISPFIYTLSTSLKDKEQISLPNSPLYPARPAKMEFEGKEYEVYRVPQPDGSLKDMAIIEKGRKTSTFIDAHDPNATPYVWEGKYRSLEPVWDFSPNWSNYPDVWKLEGKNFTFGKIILNTFLIAVIGIVGTVFSCVAVAYGFSRFRFPLKNTLFLVLIATIFLPRTVVTVPLYAFFVRIGWVGSWLPLVVPHFFANAYNVFWLRQYFMTIPREMDEAAMIDGAGPLRTLFAVILPQAWPALVTVTLSHMVFAWKDFFEPLIYLSTKPELQPISVAIQQFNALYGQQPQLIQSAAVLGLVVPVLIFFLAQRVFMQGMVFTGVDK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XR49</accession>
    <name>A0A0P6XR49_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_16515</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064144.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16515"/>
    <dbReference type="EnsemblBacteria" id="KPL72076">
        <property type="protein sequence ID" value="KPL72076"/>
        <property type="gene ID" value="ADN00_16515"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="412" mass="46585" checksum="8DE82F1D6182EC1F" modified="2016-01-20" version="1">MIIHQPEIVPAGSEVRMQARVETRAPNPGFPDSIWFSYPQAYAHALSTRADSPLAALVLVAMALGEDVECRGEASPRLIYNLSEYQRVFYHWQPQLLQKVGIHAENLTPPPANQFSAGYATTFSGGVNSFFTIQQMLTPSLKSPQWPLKYALFLQGSPDLPLAYQRKFEYLAERYATLAQELNLEWIPVRTNLMRFAANRIPFNLLLEAPLVGAALGISPILAGMVIPSGRMYERYKDAAAGPMTTYLVATESFEVITHGGAFTRFAKTQAISDWKPAQNNLRVCLDWHDDTDMNCCYCSKCLRTRMDLNVIGRLEKFTTLKSPFKFKDLILWGSQMEIGFRGEKDYLEYAWKQRKELLPGILLGILVGTPLRLARKYSPNWIKKSVFCVTDENDPENTFVQNPDIPENLAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XRF0</accession>
    <name>A0A0P6XRF0_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NodB homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_08135</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77843.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08135"/>
    <dbReference type="EnsemblBacteria" id="KPL77843">
        <property type="protein sequence ID" value="KPL77843"/>
        <property type="gene ID" value="ADN00_08135"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016810">
        <property type="term" value="F:hydrolase activity, acting on carbon-nitrogen (but not peptide) bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011330">
        <property type="entry name" value="Glyco_hydro/deAcase_b/a-brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002509">
        <property type="entry name" value="NODB_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01522">
        <property type="entry name" value="Polysacc_deac_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88713">
        <property type="entry name" value="SSF88713"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006133188" description="NodB homology domain-containing protein" evidence="1">
        <location>
            <begin position="23"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="domain" description="NodB homology" evidence="2">
        <location>
            <begin position="210"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01522"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77843.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="382" mass="42054" checksum="4E2F50EFB568C529" modified="2016-01-20" version="1">MPVCLLAGGLAACSASSSQASADLTATQVFESALLTATWSVPTATPLPTQTPTPQPTPTVVRTPPALPGVFQTSLLNKADAPRSYEQDVCAYLKNRLDPAKAQPGTVVMPIMFHSITDGPADKVYQISHETLDRLMRDLKDQDFEIISMDQLVEFLYENEWIPPRSVVLISDDLHFADYYESHFKPFLAESGGVVVNAWISKTDPNPQVIQENQRLQTEGWVDHQAHGVVHNINISALSDEAFIRSELQGSRDSILATFGKAPVAYIWPGGGFTPQAAEIALELGYKVGFTTNPRGPLMYNWIPNAQEKDANRPALIPEGDVANPLMVLPRFWDADASRYIDIVRRIGQDAALAAQETHAVEMEYYQIVCQEEYGALSVEPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XU82</accession>
    <name>A0A0P6XU82_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">P22_AR_N domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_05435</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061959.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78693">
        <property type="protein sequence ID" value="KPL78693"/>
        <property type="gene ID" value="ADN00_05435"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018875">
        <property type="entry name" value="Antirepressor_Ant_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10547">
        <property type="entry name" value="P22_AR_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="P22_AR_N" evidence="2">
        <location>
            <begin position="16"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="154"/>
            <end position="192"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF10547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="278" mass="31283" checksum="D306F295B042458A" modified="2016-01-20" version="1">MAGGPPVFKPEQERKLLFRGKEIATADLRDGKGYVSVRSLCEAFGLDQRAQRRRLLRQQGYFAPYTATIQMNTPGGPQPNLCLMASSVPLFLTGVELERVQDAETRDLLTAFLDEAHTVLAEHFGISERGELQFLRESVSRMVAEQEQFEDTISKKVEAELADLRRAHEEKVQQIREAFSDLRQQVTRLEKVAGPKARLTPEELGQLRQLVASLGTLLQEQGVPKPYPGIYMDITRLTGVSRSEDIRREDFAMVVDFLEGQIRGLTKENAKPAKAKDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XUW7</accession>
    <name>A0A0P6XUW7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_03640</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061606.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78995">
        <property type="protein sequence ID" value="KPL78995"/>
        <property type="gene ID" value="ADN00_03640"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001851">
        <property type="entry name" value="ABC_transp_permease"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02653">
        <property type="entry name" value="BPD_transp_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="57"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="87"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="109"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="143"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="193"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="241"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="268"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="292"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="319"/>
            <end position="336"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL78995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="353" mass="37440" checksum="842B51FBED8EF0D0" modified="2016-01-20" version="1">MEKSKTRITDIAFRVGAVLLALVFTTIVLIVAKAPPLKAYSEIINGSLGSMVKMADVLVAFVPLLLVTSGLLFTFTAGLYNLGIEGQIVLGAIFTTGALRMMLNSTLPPALIILLAVLAGALGGALWAALVGALKTFGGVNEIFGGLGLNFVSTALTIWLIFGPWKQPGVGSMSGTKPFPETMWLPMVSGFRLSWWSVGLAIVGILVVYGLLNGTYFGLKMKAVGKNFHASYIMGIPHTRYMMMAFILCGVFAGLAGAVQVVGVYHRLIPSISSGYGFLGLLVAMLINYQALFAIPVALFFAGLNIGSIQLPIVLKLDSALSGVLQGSLVLFVVLMEGVRQRFTRKETGKDGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XV63</accession>
    <name>A0A0P6XV63_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_09545</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77350.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062760.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000023.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09545"/>
    <dbReference type="EnsemblBacteria" id="KPL77350">
        <property type="protein sequence ID" value="KPL77350"/>
        <property type="gene ID" value="ADN00_09545"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL77350.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="325" mass="34358" checksum="3983A66294E361BA" modified="2016-01-20" version="1">MAKRIIEVSPSILAKLEGRELIDAIRVSGGRAVSAEIVAFRPGLVDGTNNGNLAATFGADIVHMNHYDVDRPQVAGFSSTPEGVEEWAKQGISLKPSDQIEDPTAAFFASMGFGITIRDLRNAIGRVVGLSLEVNFPGATAPRGRLSIPDTAERALEQGAAYLTLIGTPAHSPKILADNIRELRTALGPDPMLVAGRMPWGGSRPGMPDFMKADEVELQVEAGADMVAIAAPGTMPGATIEAVRAAVDKAHQLGALAEVSIGTSQESADEETVRRLAMDSRLTGADLYQIGDGGYSGVTLPENILSFAMAIKGRRHAYRRMAMIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XVM8</accession>
    <name>A0A0P6XVM8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Phage-shock protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">ADN00_03220</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000014">
        <property type="protein sequence ID" value="KPL79360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061531.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000014.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79360">
        <property type="protein sequence ID" value="KPL79360"/>
        <property type="gene ID" value="ADN00_03220"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2055"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007168">
        <property type="entry name" value="Phageshock_PspC_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04024">
        <property type="entry name" value="PspC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="35"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="domain" description="PspC" evidence="7">
        <location>
            <begin position="4"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF04024"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL79360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="81" mass="8954" checksum="8F870E344AA5CF72" modified="2016-01-20" version="1">MEKKRLYRSQKERMIAGVCGGLADYFDIDPTLVRLLFVLLFFLGGNGVLIYLIMLILVPSETLPASQAVVDAPAADQPNQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XVU0</accession>
    <name>A0A0P6XVU0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_02650</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000012">
        <property type="protein sequence ID" value="KPL79433.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061412.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000012.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79433">
        <property type="protein sequence ID" value="KPL79433"/>
        <property type="gene ID" value="ADN00_02650"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009061">
        <property type="entry name" value="DNA-bd_dom_put_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46955">
        <property type="entry name" value="SSF46955"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79433.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="144" mass="16177" checksum="676EB6C30DB4517C" modified="2016-01-20" version="1">MSENQNTSNCRISRNVLIKAPGLLPMLYTPREIAEDLDVPETTLRDWLNHGAPHSRDESNHIWIDGKQFAAWVDNQRNARKKPAHQLQAGEGFCMRCNTIVKIQNAEIRPVKGRLSHLKGKCPICGRIVNRGIWNAGSAELSQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XW32</accession>
    <name>A0A0P6XW32_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Glyoxalase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_08570</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000022">
        <property type="protein sequence ID" value="KPL77643.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062580.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000022.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_08570"/>
    <dbReference type="EnsemblBacteria" id="KPL77643">
        <property type="protein sequence ID" value="KPL77643"/>
        <property type="gene ID" value="ADN00_08570"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.180.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029068">
        <property type="entry name" value="Glyas_Bleomycin-R_OHBP_Dase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041581">
        <property type="entry name" value="Glyoxalase_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037523">
        <property type="entry name" value="VOC"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18029">
        <property type="entry name" value="Glyoxalase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54593">
        <property type="entry name" value="SSF54593"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51819">
        <property type="entry name" value="VOC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="VOC" evidence="1">
        <location>
            <begin position="6"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51819"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL77643.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="151" mass="16706" checksum="C3EC588F985E2DE1" modified="2016-01-20" version="1">MPLECTYTHTNIVAKDWRKLAAFYQQVFNCQPVPPERDLQGEWLQRATGVEDAHLRGAHLRLPGCGENGPTLEIFQYNTLAAESPRAINQPGLAHLAFAVNDVRAARAEVLAHGGSDLGEVVTVQVPGKGEICFVYMRDPEGNILELQRWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XWP0</accession>
    <name>A0A0P6XWP0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_14305</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000034">
        <property type="protein sequence ID" value="KPL73740.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL73740">
        <property type="protein sequence ID" value="KPL73740"/>
        <property type="gene ID" value="ADN00_14305"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL73740.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="72" mass="8233" checksum="9C16836FAE8F6F22" modified="2016-01-20" version="1">MYPPCGRIVCGAKLIPFTVLDSNSTFQAPDHSNKKDWIFRAKIIITKGTMKIFNCLIIYMNLLSPLLIEFLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XX37</accession>
    <name>A0A0P6XX37_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">2-oxoglutarate ferredoxin oxidoreductase subunit beta</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_00785</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061044.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00785"/>
    <dbReference type="EnsemblBacteria" id="KPL81094">
        <property type="protein sequence ID" value="KPL81094"/>
        <property type="gene ID" value="ADN00_00785"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3555"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003824">
        <property type="term" value="F:catalytic activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030976">
        <property type="term" value="F:thiamine pyrophosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029061">
        <property type="entry name" value="THDP-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011766">
        <property type="entry name" value="TPP_enzyme-bd_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02775">
        <property type="entry name" value="TPP_enzyme_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52518">
        <property type="entry name" value="SSF52518"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="TPP_enzyme_C" evidence="1">
        <location>
            <begin position="60"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF02775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL81094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="346" mass="38614" checksum="92E3864C7093DA48" modified="2016-01-20" version="1">MADILTEKSVNAIGMQRSDYKGLPSTLCQGCGHNSVSAQIISACYELGIDPARIVKFSGIGCSSKSPTYFLGRSFGFNGLHGRMPSLAEGALFGDTRLKGLGVSGDGDTVSIGMGQFKHIIRRNMPMVYIVENNGVYGLTKGQFSATAEKDLELKKQGRNLYSPVDICMEALIGNASFVARSFAGDPKQVKELIKASLVHNGLAVIDIISPCVTFHNLEMYMHSYTWGKKHEVPLHDLSFVPMEEEIMIEDFNQGSCREIELHDGSKILLRKLAEDYDPTNRWEALRMLEEAERKNQLVTGLIYFNPAPTNFFDMFKLTEKPLNRLEPEEIRPARDTLEMVNNLMF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="22" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y047</accession>
    <name>A0A0P6Y047_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="8 19">Adenosylcobinamide-GDP ribazoletransferase</fullName>
            <ecNumber evidence="7 19">2.7.8.26</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="18 19">Cobalamin synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="17 19">Cobalamin-5'-phosphate synthase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="19" type="primary">cobS</name>
        <name evidence="20" type="ORF">ADN00_05505</name>
    </gene>
    <organism evidence="20 21">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="20 21" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="20 21">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16 19">Joins adenosylcobinamide-GDP and alpha-ribazole to generate adenosylcobalamin (Ado-cobalamin). Also synthesizes adenosylcobalamin 5'-phosphate from adenosylcobinamide-GDP and alpha-ribazole 5'-phosphate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="2 19">
            <text>adenosylcob(III)inamide-GDP + alpha-ribazole 5'-phosphate = adenosylcob(III)alamin 5'-phosphate + GMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23560"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57918"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:60487"/>
            <dbReference type="ChEBI" id="CHEBI:60493"/>
            <dbReference type="EC" id="2.7.8.26"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 19">
            <text>adenosylcob(III)inamide-GDP + alpha-ribazole = adenosylcob(III)alamin + GMP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:16049"/>
            <dbReference type="ChEBI" id="CHEBI:10329"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:18408"/>
            <dbReference type="ChEBI" id="CHEBI:58115"/>
            <dbReference type="ChEBI" id="CHEBI:60487"/>
            <dbReference type="EC" id="2.7.8.26"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="3 19">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5 19">Cofactor biosynthesis; adenosylcobalamin biosynthesis; adenosylcobalamin from cob(II)yrinate a,c-diamide: step 7/7.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="19">Cell membrane</location>
            <topology evidence="19">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="4">Membrane</location>
            <topology evidence="4">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="6 19">Belongs to the CobS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="20">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.8.26" evidence="7 19"/>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061972.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05505"/>
    <dbReference type="EnsemblBacteria" id="KPL78703">
        <property type="protein sequence ID" value="KPL78703"/>
        <property type="gene ID" value="ADN00_05505"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1578"/>
    <dbReference type="UniPathway" id="UPA00148">
        <property type="reaction ID" value="UER00238"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051073">
        <property type="term" value="F:adenosylcobinamide-GDP ribazoletransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008818">
        <property type="term" value="F:cobalamin 5'-phosphate synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009236">
        <property type="term" value="P:cobalamin biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00719">
        <property type="entry name" value="CobS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003805">
        <property type="entry name" value="CobS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34148">
        <property type="entry name" value="PTHR34148"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02654">
        <property type="entry name" value="CobS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00317">
        <property type="entry name" value="cobS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 19" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10 19" id="KW-0169">Cobalamin biosynthesis</keyword>
    <keyword evidence="13 19" id="KW-0460">Magnesium</keyword>
    <keyword evidence="15 19" id="KW-0472">Membrane</keyword>
    <keyword evidence="21" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11 19" id="KW-0808">Transferase</keyword>
    <keyword evidence="12 19" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="14 19" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="44"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="116"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="174"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="204"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="19">
        <location>
            <begin position="233"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000357"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00004663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00010561"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00013200"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00015850"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022573"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00025228"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00032605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00032853"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00719"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="EMBL" id="KPL78703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="253" mass="26356" checksum="1B424FF1BEED7AA1" modified="2016-01-20" version="1">MAKRFHLASFLKGFRTALGFLTILPVPAAPDVNNKALAEALPWFPWAGCIVGAAAAAAAYLLSRVFSPLTASVMSAAVWALITGGLHLDGLADCCDGLLVSAPRERRLEIMKDPRLGGFGATGLFLFLLLKVAVLQTVIERSAWSVILLAAAAGRSAVYLALSQPSARPGGLGAQVRSGVSWAGILFGLIPLIGLVVWLDWPGLGAAAAGGLMCAGVLWLARNRIGGVTGDVHGMIIELVEVVVLLVYPLLLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y098</accession>
    <name>A0A0P6Y098_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">SIS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05785</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78749.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062020.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78749">
        <property type="protein sequence ID" value="KPL78749"/>
        <property type="gene ID" value="ADN00_05785"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1901135">
        <property type="term" value="P:carbohydrate derivative metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05013">
        <property type="entry name" value="SIS_RpiR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035472">
        <property type="entry name" value="RpiR-like_SIS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001347">
        <property type="entry name" value="SIS_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13580">
        <property type="entry name" value="SIS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SSF53697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51464">
        <property type="entry name" value="SIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SIS" evidence="1">
        <location>
            <begin position="32"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78749.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="252" mass="27509" checksum="3C14516B5EAB3C24" modified="2016-01-20" version="1">MSAESYLQKIQKLISDLDQTSMIEIKKAARAMANSIKAGRVVYYYGSGHSALPCLDVFPRYGTFVGIQPIHDPRLTWNNVLGPGGTPELLWLERVEGYVKNVFRSYEITPEDTLIVFSHGGLNAAGIEAAMIGKECGATVVAVTSMQNYRKNPAKHSSGQKLADVAHIAIDNGAPPEDAIIYVNGWEEPVAAASTVMAITISMALIAETAKILSDEGIYRPTFASPNVVTDPDHDLKVYDEYKKFHKTISGY</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y254</accession>
    <name>A0A0P6Y254_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_03790</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79023.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03790"/>
    <dbReference type="EnsemblBacteria" id="KPL79023">
        <property type="protein sequence ID" value="KPL79023"/>
        <property type="gene ID" value="ADN00_03790"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011110">
        <property type="entry name" value="Reg_prop"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011712">
        <property type="entry name" value="Sig_transdc_His_kin_sub3_dim/P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011123">
        <property type="entry name" value="Y_Y_Y"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13185">
        <property type="entry name" value="GAF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07730">
        <property type="entry name" value="HisKA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07494">
        <property type="entry name" value="Reg_prop"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07495">
        <property type="entry name" value="Y_Y_Y"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00065">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="SSF55874"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GAF" evidence="1">
        <location>
            <begin position="917"/>
            <end position="1076"/>
        </location>
    </feature>
    <feature type="domain" description="HATPase_c" evidence="2">
        <location>
            <begin position="1187"/>
            <end position="1280"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00387"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79023.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="1285" mass="142880" checksum="25144169DD155DE8" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y487</accession>
    <name>A0A0P6Y487_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6 7">Transaldolase</fullName>
            <ecNumber evidence="6 7">2.2.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">tal</name>
        <name evidence="8" type="ORF">ADN00_02175</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="8 9" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="8 9">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2 7">Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 7">
            <text>D-glyceraldehyde 3-phosphate + D-sedoheptulose 7-phosphate = beta-D-fructose 6-phosphate + D-erythrose 4-phosphate</text>
            <dbReference type="Rhea" id="RHEA:17053"/>
            <dbReference type="ChEBI" id="CHEBI:16897"/>
            <dbReference type="ChEBI" id="CHEBI:57483"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:59776"/>
            <dbReference type="EC" id="2.2.1.2"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="4 7">Carbohydrate degradation; pentose phosphate pathway; D-glyceraldehyde 3-phosphate and beta-D-fructose 6-phosphate from D-ribose 5-phosphate and D-xylulose 5-phosphate (non-oxidative stage): step 2/3.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3 7">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5 7">Belongs to the transaldolase family. Type 2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.2.1.2" evidence="6 7"/>
    <dbReference type="EMBL" id="LGCL01000009">
        <property type="protein sequence ID" value="KPL79791.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061323.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000009.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02175"/>
    <dbReference type="EnsemblBacteria" id="KPL79791">
        <property type="protein sequence ID" value="KPL79791"/>
        <property type="gene ID" value="ADN00_02175"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2757"/>
    <dbReference type="UniPathway" id="UPA00115">
        <property type="reaction ID" value="UER00414"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004801">
        <property type="term" value="F:transaldolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006098">
        <property type="term" value="P:pentose-phosphate shunt"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00955">
        <property type="entry name" value="Transaldolase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00493">
        <property type="entry name" value="Transaldolase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001585">
        <property type="entry name" value="TAL/FSA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004732">
        <property type="entry name" value="Transaldolase_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018225">
        <property type="entry name" value="Transaldolase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10683">
        <property type="entry name" value="PTHR10683"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00923">
        <property type="entry name" value="TAL_FSA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036915">
        <property type="entry name" value="Trnald_Bac_Plnt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00876">
        <property type="entry name" value="tal_mycobact"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01054">
        <property type="entry name" value="TRANSALDOLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0570">Pentose shunt</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0704">Schiff base</keyword>
    <keyword evidence="7 8" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Schiff-base intermediate with substrate" evidence="7">
        <location>
            <position position="139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001469"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00004857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00008426"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00013151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00493"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KPL79791.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="370" mass="40597" checksum="DDF3D52DF9144195" modified="2016-01-20" version="1">MSDIPKLHALGQSIWYDNIQRKLLENGYLSGLIASGDIRGVTSNPSIFHAAITKSSDYDAALEPLAQKGLSAEEIFYELAVEDIRNAADLFQNLYQETDALDGYVSIEVSPYLAKDEQGTVAEALRLWQWIDRPNICIKIPATQEGIGAIRAAIAAGINVNVTLIFSLERYADVIEAYLSGLEDRVAQGLPVNHIASVASFFVSRVDSSVDSLLDAIAQQAGPNAAKAQSLKGKAAIANARLAYNLFKDKFFTERFEKLQAHGARVQRPLWASTSTKNPQYRDVIYVEELIGPYTVNTMPPQTLDAFRDHGKAALTVDVPREESQAVINDLQSLGISMSQVTEQLEIDGVKAFSDAFTSLLTSLEERAQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y4I7</accession>
    <name>A0A0P6Y4I7_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">PMT_2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">ADN00_11150</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76519.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063091.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11150"/>
    <dbReference type="EnsemblBacteria" id="KPL76519">
        <property type="protein sequence ID" value="KPL76519"/>
        <property type="gene ID" value="ADN00_11150"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.926"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038731">
        <property type="entry name" value="RgtA/B/C-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13231">
        <property type="entry name" value="PMT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="5 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="88"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="170"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="221"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="247"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="292"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="375"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="401"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="426"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="455"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="domain" description="PMT_2" evidence="10">
        <location>
            <begin position="155"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF13231"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL76519.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="753" mass="83896" checksum="AB27C5094ECEC115" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y4L8</accession>
    <name>A0A0P6Y4L8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Nucleotide sugar epimerase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_01895</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000007">
        <property type="protein sequence ID" value="KPL80047.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061270.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000007.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_01895"/>
    <dbReference type="EnsemblBacteria" id="KPL80047">
        <property type="protein sequence ID" value="KPL80047"/>
        <property type="gene ID" value="ADN00_01895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016040">
        <property type="entry name" value="NAD(P)-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16363">
        <property type="entry name" value="GDP_Man_Dehyd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NAD(P)-bd_dom" evidence="1">
        <location>
            <begin position="5"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF16363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80047.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="324" mass="36538" checksum="EDA24F1E37447F83" modified="2016-01-20" version="1">MANYLVTGAAGFIGARVSELLLQDGHTVLGVDDLNDAYDVRLKEWRLKRLAGQPGFRLFQQDLRDYQRLKPVFESGPIDAVINLAARAGVRYSVENPFIYLETNNNAVLNLLEQCKIHGVPKFILASTSSIYGLNAPMPTPEETNSDHPLQPYSASKKGAEAMCHAYHFLHGLDVTIFRFFTVYGPAGRPDMVMFRFCQWIAEGRPVHLNGDGEQTRGFTYVDDIARGTILGLKPLGYEIINLGGHEVISINEMISVLEELIGKKANVVFHEAHKADMLSNWADVSKARRMLGWEPQVSLREGMRRLVEWYMQEREWTSQVLTP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y4R9</accession>
    <name>A0A0P6Y4R9_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">CYTH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_11140</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11140"/>
    <dbReference type="EnsemblBacteria" id="KPL76583">
        <property type="protein sequence ID" value="KPL76583"/>
        <property type="gene ID" value="ADN00_11140"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd07890">
        <property type="entry name" value="CYTH-like_AC_IV-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008173">
        <property type="entry name" value="Adenylyl_cyclase_CyaB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033469">
        <property type="entry name" value="CYTH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023577">
        <property type="entry name" value="CYTH_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01928">
        <property type="entry name" value="CYTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55154">
        <property type="entry name" value="SSF55154"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00318">
        <property type="entry name" value="cyaB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51707">
        <property type="entry name" value="CYTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CYTH" evidence="1">
        <location>
            <begin position="1"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="196" mass="23126" checksum="7A7E47EEE084473B" modified="2016-01-20" version="1">MEVKFFVRDLSEIAQRITEMGGRLVHSRMYEVNLRYEKGDRELYKRMEVLRLRKDFASRLTFKGPYQEDPSVSRRVEIEFEVSNFDNAKKFLEALGYHLDVMYEKNRTTYAIRNVLVVLDEMPYGSFLEIEGPDAESIQQVARDLNLKWEARCTESYIMLFDRLVAKKGLTAKHLSFEEFEGLSFVAEDFDLEFAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y5I1</accession>
    <name>A0A0P6Y5I1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76848.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76848">
        <property type="protein sequence ID" value="KPL76848"/>
        <property type="gene ID" value="ADN00_09590"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071586">
        <property type="term" value="P:CAAX-box protein processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003675">
        <property type="entry name" value="Rce1-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02517">
        <property type="entry name" value="Rce1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="31"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="85"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="127"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="156"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="187"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="216"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76848.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="240" mass="26505" checksum="E12991733CE55780" modified="2016-01-20" version="1">MAKPLGGAGLLQFGFIHLGDFSMKNNTFWKILTIVELIAAAAIILLDVLIPTLLILGLIIISLLIRREHIRSLGFKRPQSWPKMLGFVFLSVVFLQLFDIGVTVPILNRLTGKTIDYSGFAHLQGNLGQLALLLVISWTLAALGEEMVYRGYLQKLLTDLFGSGLPGILLTVGVSSLLFGLAHTEQGLVGVVVATFDALFFSWLKYKFENNLWASILAHGFYNSIGVIIFYFTGPIYGLW</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y5J0</accession>
    <name>A0A0P6Y5J0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Cupin</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_09645</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76857.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062792.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09645"/>
    <dbReference type="EnsemblBacteria" id="KPL76857">
        <property type="protein sequence ID" value="KPL76857"/>
        <property type="gene ID" value="ADN00_09645"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2386"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013096">
        <property type="entry name" value="Cupin_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011051">
        <property type="entry name" value="RmlC_Cupin_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07883">
        <property type="entry name" value="Cupin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51182">
        <property type="entry name" value="SSF51182"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cupin_2" evidence="1">
        <location>
            <begin position="34"/>
            <end position="105"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76857.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="127" mass="14038" checksum="8E63B7D3C27CA167" modified="2016-01-20" version="1">MKTTILPQYPDAKSPAGADIRYMMDGKTGNMIHSTVPPHQVNRATVHATVGEFWYVLEGRGEIWRDDGVESCVTALVPGTAIDIPVGTAFQYRNISDEDLKFICISMPRWPGDAEATYVKGIWPPTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y5S7</accession>
    <name>A0A0P6Y5S7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_10240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062905.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76958">
        <property type="protein sequence ID" value="KPL76958"/>
        <property type="gene ID" value="ADN00_10240"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="110"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="164" mass="18145" checksum="B497C1CCCE87DEDF" modified="2016-01-20" version="1">MIDLVKIAIDGAILSALATLLISISMRTNPRIWLHDYPKEIQAAVPPKTAEEKRLSLIFGIPFLILLAAGPFISTLTLPQRASLPFWALFANASGVMFVFNVIDWLVLDWLIFCTITPSIMVIPGTQGMAAYKDYAFHFRGFLIGTLFSVVFGLVIAAVVYLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y6P7</accession>
    <name>A0A0P6Y6P7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_00870</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000002">
        <property type="protein sequence ID" value="KPL81108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061059.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000002.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_00870"/>
    <dbReference type="EnsemblBacteria" id="KPL81108">
        <property type="protein sequence ID" value="KPL81108"/>
        <property type="gene ID" value="ADN00_00870"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_repeat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="SSF50978"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="486"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="1">
        <location>
            <begin position="658"/>
            <end position="699"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL81108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="762" mass="84718" checksum="712367CA9FFF142A" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y906</accession>
    <name>A0A0P6Y906_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Lactamase_B domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_07055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78229.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062279.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07055"/>
    <dbReference type="EnsemblBacteria" id="KPL78229">
        <property type="protein sequence ID" value="KPL78229"/>
        <property type="gene ID" value="ADN00_07055"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12706">
        <property type="entry name" value="Lactamase_B_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lactamase_B" evidence="1">
        <location>
            <begin position="19"/>
            <end position="195"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78229.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="251" mass="28419" checksum="2D046E41A5131CD6" modified="2016-01-20" version="1">MGKLILLGTAAAVPDHDRENTHFWLECGERRMLIDCATNPVAHLPRVGLDFMTLTDLVLTHFHPDHVSGAPYLLMVMWLKGRKDRLRVYGLEDTLEKFKRLLQLFDWESWPNFYPVEFIAVSERENAPVLGDDHLRVTASPVRHLIPTMGLRVDFLKSGASFAYSCDTQPCEEVARLAARADVLLHEAGGYGVGHTSPEKAGETAQKAGVKRLYLVHYPDVSEQEWVEKASQYFSGEVRLAKEREEILFAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="23" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y9B4</accession>
    <name>A0A0P6Y9B4_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">FtsK domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_07080</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FtsK/SpoIIIE/SftA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07080"/>
    <dbReference type="EnsemblBacteria" id="KPL78348">
        <property type="protein sequence ID" value="KPL78348"/>
        <property type="gene ID" value="ADN00_07080"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3234"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041027">
        <property type="entry name" value="FtsK_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002543">
        <property type="entry name" value="FtsK_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018541">
        <property type="entry name" value="Ftsk_gamma"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036390">
        <property type="entry name" value="WH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17854">
        <property type="entry name" value="FtsK_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09397">
        <property type="entry name" value="FtsK_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01580">
        <property type="entry name" value="FtsK_SpoIIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00843">
        <property type="entry name" value="Ftsk_gamma"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46785">
        <property type="entry name" value="SSF46785"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50901">
        <property type="entry name" value="FTSK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="12"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="45"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="80"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="FtsK" evidence="6">
        <location>
            <begin position="354"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="168"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="662"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="186"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="binding site" evidence="3">
        <location>
            <begin position="371"/>
            <end position="378"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006474"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00289"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50901"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL78348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="700" mass="76524" checksum="D2F21B823729AF17" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YAF2</accession>
    <name>A0A0P6YAF2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="5">(4Fe-4S)-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_06285</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78823.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062110.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06285"/>
    <dbReference type="EnsemblBacteria" id="KPL78823">
        <property type="protein sequence ID" value="KPL78823"/>
        <property type="gene ID" value="ADN00_06285"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1759"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051536">
        <property type="term" value="F:iron-sulfur cluster binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017896">
        <property type="entry name" value="4Fe4S_Fe-S-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017900">
        <property type="entry name" value="4Fe4S_Fe_S_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002586">
        <property type="entry name" value="CobQ/CobB/MinD/ParA_Nub-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01656">
        <property type="entry name" value="CbiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12838">
        <property type="entry name" value="Fer4_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00198">
        <property type="entry name" value="4FE4S_FER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51379">
        <property type="entry name" value="4FE4S_FER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0408">Iron</keyword>
    <keyword evidence="3" id="KW-0411">Iron-sulfur</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="70"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="domain" description="4Fe-4S ferredoxin-type" evidence="4">
        <location>
            <begin position="102"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL78823.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="310" mass="33216" checksum="D2A52F14D8C679BB" modified="2016-01-20" version="1">MLNQPRRAQQLVVLSGKGGTGKTSLCAAFAHLANQNSLSAIFVDADVDAANLSLVLRPNQSETHEFWGGSLAEITPHLCTGCGACESVCRYDAALPDPHSLGKYAIDPIACDGCAACVYACPEEAIRMVQQQEGNWFHSQTAYGELFHAELFPGRENSGKLVTLVKQQARLRAEESHLPLMVVDGPPGIGCPVISACAGADLGLVVTEPSLAGLHDLKRVFGTLQHFHVPVLVCINKADLYPEGARQIREFAEEQGVEIAGEIPFDESVPQAMLAGLPINEMFPKSPAAQAAAQTWAATMARMMDLQVNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YAP3</accession>
    <name>A0A0P6YAP3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_03440</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL78960.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061567.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78960">
        <property type="protein sequence ID" value="KPL78960"/>
        <property type="gene ID" value="ADN00_03440"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78960.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="141" mass="15970" checksum="355AE04A800E7740" modified="2016-01-20" version="1">MKQALFAGLIVDENDQSVQVRYVGSEPCYVVDDAGFLRHIESEKVDRQVLDELKRFISEHKDLVIQQMAESLGQPDIFSMAVLQNQLDHLDQQFDQMLYTGIPEEGRAYMGMMGFKIVIDHHGQVLHIEQPGAAPGPDQED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="28" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YAT1</accession>
    <name>A0A0P6YAT1_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pantothenate synthetase</fullName>
            <shortName evidence="5">PS</shortName>
            <ecNumber evidence="5">6.3.2.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">Pantoate--beta-alanine ligase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="5">Pantoate-activating enzyme</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="5" type="primary">panC</name>
        <name evidence="6" type="ORF">ADN00_03700</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 5">
            <text>(R)-pantoate + ATP + beta-alanine = (R)-pantothenate + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10912"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15980"/>
            <dbReference type="ChEBI" id="CHEBI:29032"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:57966"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.2.1"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2 5">Cofactor biosynthesis; (R)-pantothenate biosynthesis; (R)-pantothenate from (R)-pantoate and beta-alanine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="5">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="miscellaneous">
        <text evidence="5">The reaction proceeds by a bi uni uni bi ping pong mechanism.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 5">Belongs to the pantothenate synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.2.1" evidence="5"/>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061616.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_03700"/>
    <dbReference type="EnsemblBacteria" id="KPL79006">
        <property type="protein sequence ID" value="KPL79006"/>
        <property type="gene ID" value="ADN00_03700"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.92"/>
    <dbReference type="UniPathway" id="UPA00028">
        <property type="reaction ID" value="UER00005"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004592">
        <property type="term" value="F:pantoate-beta-alanine ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015940">
        <property type="term" value="P:pantothenate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00560">
        <property type="entry name" value="PanC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1300.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00158">
        <property type="entry name" value="PanC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004821">
        <property type="entry name" value="Cyt_trans-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003721">
        <property type="entry name" value="Pantoate_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042176">
        <property type="entry name" value="Pantoate_ligase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21299:SF1">
        <property type="entry name" value="PTHR21299:SF1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02569">
        <property type="entry name" value="Pantoate_ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00125">
        <property type="entry name" value="cyt_tran_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00018">
        <property type="entry name" value="panC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5 6" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 5" id="KW-0566">Pantothenate biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="active site" description="Proton donor" evidence="5">
        <location>
            <position position="34"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="27"/>
            <end position="34"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="58"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="144"/>
            <end position="147"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>(R)-pantoate</name>
            <dbReference type="ChEBI" id="CHEBI:15980"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="173"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <begin position="181"/>
            <end position="184"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004990"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009256"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL79006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="277" mass="30301" checksum="0EA758942B12CA54" modified="2016-01-20" version="1">MKLVSTLEDLRQHRQALANPLGFVPTMGFLHEGHLSLVRAAKAACPSVAVSIFVNPTQFGPTEDLAAYPRDLEHDLALLEAEGVDLVWAPTPEVMYPAGYQTWVEVTDVTQFLEGKMRPGHFKGVTTVVAKLFNAVQPQHAFFGQKDAQQAVVITRMVQDLNMPVELHICPIVREPDGLAMSSRNTYLSPAERQAALVLSRSLQTARAAFEQGQRNADALRQTVLSVLAAEPLARVQYVSCADPSTLAEQSGVISQTLISMAVYVGKTRLIDNIILQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GKL2</accession>
    <name>A0A0N8GKL2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Cobalt ABC transporter permease</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_18260</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70010.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064485.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18260"/>
    <dbReference type="EnsemblBacteria" id="KPL70010">
        <property type="protein sequence ID" value="KPL70010"/>
        <property type="gene ID" value="ADN00_18260"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003339">
        <property type="entry name" value="ABC/ECF_trnsptr_transmembrane"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02361">
        <property type="entry name" value="CbiQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="20"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="66"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="97"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="140"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="230"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL70010.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="260" mass="29663" checksum="005051BF8EBA520C" modified="2016-01-20" version="1">MDQEIYLDRKTFFHKLDPRTKIVILLVAFVLILYFENPLWVLPLTLLILLHGYFSESLVNLKRIRLIMIILTISSMILWSFFSNGVTPFVWVIELEAFQFAMARTMVMLSLITEGMIFLSTTRTEEFVLGMIRFGLPYRVGFAISTAFRMVPTIVSNVFIIAQAQRSRGLDLDSGNLLQRIRKYIPLLIPVFVSTIRNTNVFGMALEAKGFGAQNDRTNYYSSEFGKGDYIVMLVMGVLFAVTTYLKIMGFGGIPGLTKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GKM2</accession>
    <name>A0A0N8GKM2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_18780</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064574.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70090">
        <property type="protein sequence ID" value="KPL70090"/>
        <property type="gene ID" value="ADN00_18780"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL70090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="65" mass="7197" checksum="27755BDD2DA10BE1" modified="2016-01-20" version="1">MPNVMSTFSLDIDTIQRLDRIADALQAGKSETIRKLVEEKFEQLQAAGVFEPALAASKTLTETEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GLC6</accession>
    <name>A0A0N8GLC6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Sugar ABC transporter substrate-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_16605</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72122.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16605"/>
    <dbReference type="EnsemblBacteria" id="KPL72122">
        <property type="protein sequence ID" value="KPL72122"/>
        <property type="gene ID" value="ADN00_16605"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3764"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025997">
        <property type="entry name" value="SBP_2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13407">
        <property type="entry name" value="Peripla_BP_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peripla_BP_4" evidence="1">
        <location>
            <begin position="68"/>
            <end position="314"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13407"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL72122.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="368" mass="38623" checksum="45312932C14280D3" modified="2016-01-20" version="1">MEPTAVPAAAEPAAEEAAPAVDFEAALASLEGQVFSTGPNGETPTAASEITLTDEELAQIKDMNATAAIVLHYAGNDWSNAQIEGLKYQFEKMGIEVVAVTDAGFKTEKQVADLETVLAKQPDIIVSIPTDPVATSNAYLQAAEQGVQLVFMDNVAADLVQGEDYVSVVSADNYGNGVASAHLMAKYIGGKGKIGIVYHEADFFVTRQRYEAFKKTIEENYPEIEIVVEQGIAGPDFAGDGEKAASAMLTKYADLAGIWGVWDVPAEGILAASRAMGREDLVITTIDLGLNVAVDIASGGPVKGLGAQRPFDQGVTEAILAGYGLLGKPAPAYVALSALPVTPENVLEAWDMVYHQAAPEALTSAMGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-06-02" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GND6</accession>
    <name>A0A0N8GND6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_07895</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77802.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77802">
        <property type="protein sequence ID" value="KPL77802"/>
        <property type="gene ID" value="ADN00_07895"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006025818" evidence="2">
        <location>
            <begin position="27"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="31"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77802.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="171" mass="18980" checksum="0C1241C6895B2BEA" modified="2016-01-20" version="1">MKNKMFTRMLSALGLIAMLLAACAPAQTPPPATLAPTSTPLPTRQPTSTPLPTATLTPIPSVTPTQTQTPLPTPPDDAAKARLFAQGERPGYQYFLTIEFPEAIQGSYYAQVDQNKPYQCSPISDQKNRLYCYGRIPGYDKYFTFTLYDQQTDLEIYSTQFFVPLTIAVED</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNL4</accession>
    <name>A0A0N8GNL4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_06790</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000018">
        <property type="protein sequence ID" value="KPL78426.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062226.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000018.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06790"/>
    <dbReference type="EnsemblBacteria" id="KPL78426">
        <property type="protein sequence ID" value="KPL78426"/>
        <property type="gene ID" value="ADN00_06790"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010390">
        <property type="entry name" value="DUF990"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06182">
        <property type="entry name" value="ABC2_membrane_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="57"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="113"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="181"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="229"/>
            <end position="251"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78426.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="263" mass="28623" checksum="1FC77C7630806E83" modified="2016-01-20" version="1">MNLRGGWALIRRTWLSWMQHRAFFFILAFGWMVPPLVSLLVWSAAAGQGSLGGYSRGGFAAYYLVLIFVNQFTYAQANWTLGDVIRMGELNTWLLQPLPAVYQVLSSEAAGKTVTLAFVLPVAGALALILRPEMQVSGSALLLFLLSLALAWLLRFVWGYWLALLAFWYTRADALLAVQDALVFLLSGVVAPVTLLPGLLQGAARLLPFRYMVGFPVEVLMDGLPAGEVAFGLAVQAGWAALALLLAALMWRAGIKRYSAVGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNR6</accession>
    <name>A0A0N8GNR6_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_06390</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062129.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78842">
        <property type="protein sequence ID" value="KPL78842"/>
        <property type="gene ID" value="ADN00_06390"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1781"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004177">
        <property type="term" value="F:aminopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008235">
        <property type="term" value="F:metalloexopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046914">
        <property type="term" value="F:transition metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_NTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000587">
        <property type="entry name" value="Creatinase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001714">
        <property type="entry name" value="Pept_M24_MAP"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01321">
        <property type="entry name" value="Creatinase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00599">
        <property type="entry name" value="MAPEPTIDASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="SSF53092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Creatinase_N" evidence="2">
        <location>
            <begin position="6"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="Peptidase_M24" evidence="1">
        <location>
            <begin position="138"/>
            <end position="341"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL78842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="361" mass="39775" checksum="E3C03786E38B1264" modified="2016-01-20" version="1">METTQRIEKLRAWLSDQNLDAAYISSYENRRYFSEFTGSNGYLIITLGELVLITDQRYTLQATQQAVGYKVVTHLLDPLPTIKEAIDSLSIRTLAYETRKLTDFDTRGYRSALPHIDWVPMEDIGKQLRAVKDAGEQEKLRQAIAIADRAVARLVNIIQPGMTEKEVAIELEYCLAKEGSEGPAFGTIVASGVRGSLPHGGPTDKRIEAGEMVVVDCGAIFQGYHSDITRTIWVGEPSDKMVEIYNIVADAQKQAFSVIKPGITGGDIDRAHRTVFEQAGVEQYALRGLGHGVGLEIHEQPRVVIGSQEMMQPGMIFTVEPGLYLPEIGGVRIEDIVLVTENGCEVLTACPQTLRVEIGVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GNU3</accession>
    <name>A0A0N8GNU3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_04030</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79058.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_04030"/>
    <dbReference type="EnsemblBacteria" id="KPL79058">
        <property type="protein sequence ID" value="KPL79058"/>
        <property type="gene ID" value="ADN00_04030"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006025817" evidence="2">
        <location>
            <begin position="36"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL79058.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="347" mass="36922" checksum="69E2572F56D77444" modified="2016-01-20" version="1">MKAFKAGGWLSLGILLLAACTRPAALMPAPMGATASVLPTASATLAAAAGEPATDTPVVPPTYTPEPPTETVQVLPSHTPTDAITPTPDDTQLVETIFAPTATRGPLPTRTRRPTATPTITPTPTPPRASLMITRPGLLSKILSPYQMEAMVTRGMDGIVYLDLIGEDGRTVASQALDYRSSLYQRFWIAPLIDFEISGVAETARLVMSTKDEFGRSMAVSSVDLVLLSLGSNETTPSLIEMEPYLIRYPKEDSLVSGGLMWVSGVARPVNESPLILELVDEQGNVVGSNRIQVPAPTGDLSHTPFGVEIEYTVSEITGVRLVIRQESVNRIPGTVALSSMTLFVAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="8" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GP70</accession>
    <name>A0A0N8GP70_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_02000</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000007">
        <property type="protein sequence ID" value="KPL80074.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_02000"/>
    <dbReference type="EnsemblBacteria" id="KPL80074">
        <property type="protein sequence ID" value="KPL80074"/>
        <property type="gene ID" value="ADN00_02000"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006750">
        <property type="entry name" value="YdcZ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34821">
        <property type="entry name" value="PTHR34821"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04657">
        <property type="entry name" value="DMT_YdcZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="44"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="72"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="104"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL80074.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="122" mass="12535" checksum="3DB026250A66B963" modified="2016-01-20" version="1">MASLLSLRLGMLSSVFIIHIGGAIVALVPLVLSGGQQIREWRGVPWYALAAGALGLIVVGGVSFTIPRIGAAATATLMVVGQLLIAAAVDHFGLLGAVQRPIDLARVAGFLLLVAGAWLVTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0N8GPC7</accession>
    <name>A0A0N8GPC7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_01400</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000004">
        <property type="protein sequence ID" value="KPL80530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061174.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000004.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL80530">
        <property type="protein sequence ID" value="KPL80530"/>
        <property type="gene ID" value="ADN00_01400"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL80530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="77" mass="8534" checksum="2C6D1A17F4E9F9E4" modified="2016-01-20" version="1">MSHGLSIDRQWVLVLSGGEIVVDWGDDRFQDVREGGFLERHAVAGAVVAPDAQLESLKQAGIVSAYNQRQVYFTYLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WN35</accession>
    <name>A0A0P6WN35_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 10">Flagellar biosynthetic protein FliR</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">ADN00_17180</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="11 12" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="11 12">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1 10">Role in flagellar biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="10">Cell membrane</location>
            <topology evidence="10">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Bacterial flagellum basal body</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 10">Belongs to the FliR/MopE/SpaR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000041">
        <property type="protein sequence ID" value="KPL71423.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064281.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000041.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17180"/>
    <dbReference type="EnsemblBacteria" id="KPL71423">
        <property type="protein sequence ID" value="KPL71423"/>
        <property type="gene ID" value="ADN00_17180"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.498"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009425">
        <property type="term" value="C:bacterial-type flagellum basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044780">
        <property type="term" value="P:bacterial-type flagellum assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006605">
        <property type="term" value="P:protein targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006303">
        <property type="entry name" value="FliR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002010">
        <property type="entry name" value="T3SS_IM_R"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30065">
        <property type="entry name" value="PTHR30065"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01311">
        <property type="entry name" value="Bac_export_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00953">
        <property type="entry name" value="TYPE3IMRPROT"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01400">
        <property type="entry name" value="fliR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0975">Bacterial flagellum</keyword>
    <keyword evidence="5 10" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="36"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="65"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="125"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="168"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="213"/>
            <end position="237"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002578"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00009772"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00021717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU362071"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KPL71423.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="256" mass="26885" checksum="D6D013E617C861A0" modified="2016-01-20" version="1">MLISVLQAQMFFLVVTRVLATIIHVPVLGGNTIPNQVRLAFGITLAVVLVPWQSQAAASDPGMTLFPFALAIGREILVGTVAGYAAAITFGAIQMAGETMGLGSGFGSGRVLNPAMGESGSPMDALFYTFSILIFLVMNGHHMFLVGLQKTFEVMPVASTLPVLKPDVIIGMTTGLIVAGIRMALPVMGALLLTDLVLGLLARVAPQIQVFFLGMPLKIGVGLLVLSVALVAFIPLLEDLFQQIAPRMLTLLAGEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WQB0</accession>
    <name>A0A0P6WQB0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_15630</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72246.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063963.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000039.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72246">
        <property type="protein sequence ID" value="KPL72246"/>
        <property type="gene ID" value="ADN00_15630"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72246.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="112" mass="12614" checksum="9667B18204039D12" modified="2016-01-20" version="1">MCNLSDSEMQEIIEEAISTPLSEQLAEADQVQDYVEIEEDEIEDEEDASQYDDMTEYEVSDLIANAIYMWLDEEDCDASISTYEQAGVLTNNEGLVVTINGKKFQVTVVRAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WVS8</accession>
    <name>A0A0P6WVS8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_14940</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Cell wall biogenesis; peptidoglycan biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000036">
        <property type="protein sequence ID" value="KPL73084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14940"/>
    <dbReference type="EnsemblBacteria" id="KPL73084">
        <property type="protein sequence ID" value="KPL73084"/>
        <property type="gene ID" value="ADN00_14940"/>
    </dbReference>
    <dbReference type="UniPathway" id="UPA00219"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009252">
        <property type="term" value="P:peptidoglycan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd16913">
        <property type="entry name" value="YkuD_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.440.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005490">
        <property type="entry name" value="LD_TPept_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022029">
        <property type="entry name" value="PG-bd_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038063">
        <property type="entry name" value="Transpep_catalytic_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12229">
        <property type="entry name" value="PG_binding_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03734">
        <property type="entry name" value="YkuD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF141523">
        <property type="entry name" value="SSF141523"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="SSF54106"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="21"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="domain" description="LysM" evidence="4">
        <location>
            <begin position="323"/>
            <end position="367"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004752"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL73084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="506" mass="55910" checksum="C1B917CB59166D4F" modified="2016-01-20" version="1">MQSLPNTQLSFKKSSSVNINFLAAGVVIVLLALIFWCVFFFVWGYFHVSQRILPGVTAAGVQVGGMTISEAEAAIHEQWNMGHQVLIGSEDQWWRTPSLSLGIYVDSVKIARDAFEMGRGSGALAEWITILLGGQPSGGPEILFNEEMARNTLTQISQLVYAAPQPNEIVYENGQWVAKGGLNGKALDVERAVLILRSDPGRVLSQGQLELTYVPIAVETVNSEILQVLNQIGNRPLTASLYDPFSGDIRDYEIGMDRIGPYLGWDAQTQSMTLNTTGLIAEVTTMLETSQGVKVRMDDDLSAVEEAWKSGRSLEFSVVDLPRPYQVESGDTLLKISQKFRLPYWYILQANPGIQPNSLIVGAEITIPSRNEMLPLPYVRNKRIVISIPEQRMRVYENGEQVHEFIVSTGIATSPTFPGVYQVRTHELSAYASNWDLTMPHFLGIYEAWPGFMNGIHGLPTLSNGRILWGNVLGGPASYGCIILSLENAELLYQWAEDGVVVEIIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WVW3</accession>
    <name>A0A0P6WVW3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_15055</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000036">
        <property type="protein sequence ID" value="KPL73102.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063857.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000036.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_15055"/>
    <dbReference type="EnsemblBacteria" id="KPL73102">
        <property type="protein sequence ID" value="KPL73102"/>
        <property type="gene ID" value="ADN00_15055"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990397">
        <property type="term" value="P:queuosine salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003744">
        <property type="entry name" value="YhhQ"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34300">
        <property type="entry name" value="PTHR34300"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02592">
        <property type="entry name" value="Vut_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00697">
        <property type="entry name" value="TIGR00697"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="28"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="98"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="173"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL73102.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="200" mass="22252" checksum="96942DA60A50707A" modified="2016-01-20" version="1">MISALLVSVSYIAAQMLADISSLQIVRVFGMSLDAGTFIYPITFTLRDLAHKVLGVKGVRVLIIAAAVINLFMAFYFWFVSRLTPDTAAGSSEIWGQVLAPVWRITLASIAAEVVAELIDTEAYRIWVEKVTHKYQWMRVLVSNAVSVPVDSAMFSFLAFFGMMPLTSVIQIFWGNVIIKGAVTFFSLPLIYSVRDQNEK</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WXA8</accession>
    <name>A0A0P6WXA8_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Flavodoxin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_17865</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000043">
        <property type="protein sequence ID" value="KPL70901.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064403.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000043.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17865"/>
    <dbReference type="EnsemblBacteria" id="KPL70901">
        <property type="protein sequence ID" value="KPL70901"/>
        <property type="gene ID" value="ADN00_17865"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026816">
        <property type="entry name" value="Flavodoxin_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12724">
        <property type="entry name" value="Flavodoxin_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="SSF52218"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="1">
        <location>
            <begin position="5"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL70901.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="170" mass="18372" checksum="7C2A6A4E4B269A45" modified="2016-01-20" version="1">MTKKILVAYATYTGSTAGVAERIGQTLTSADVTAEVKPVDQITSLDGYDAVVVGSPVRAGQLHKDMLAFLGARQPQLAALPVAYFVVCMSMKEDTPEQRCEADAYLNAARQAAPGVQPISAGLFAGAIDMKKLAFPLRLIMKAMKAEPGDYRDWEKIDAWVREIQPKLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6WZ78</accession>
    <name>A0A0P6WZ78_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">DegT/DnrJ/EryC1/StrS aminotransferase</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_16155</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the DegT/DnrJ/EryC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000040">
        <property type="protein sequence ID" value="KPL72022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064076.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000040.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_16155"/>
    <dbReference type="EnsemblBacteria" id="KPL72022">
        <property type="protein sequence ID" value="KPL72022"/>
        <property type="gene ID" value="ADN00_16155"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3666"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008483">
        <property type="term" value="F:transaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00616">
        <property type="entry name" value="AHBA_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000653">
        <property type="entry name" value="DegT/StrS_aminotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30244">
        <property type="entry name" value="PTHR30244"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01041">
        <property type="entry name" value="DegT_DnrJ_EryC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000390">
        <property type="entry name" value="PLP_StrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="SSF53383"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0032">Aminotransferase</keyword>
    <keyword evidence="2 3" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="active site" description="Proton acceptor" evidence="1">
        <location>
            <position position="184"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="2">
        <location>
            <position position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR000390-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU004508"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL72022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="382" mass="42849" checksum="F690A20286AEF9F2" modified="2016-01-20" version="1">MELKIPLADIDFNQEEEEAVLRVLRSRWLTMGAVTQEFEQAFAQYVGAKHALAVSNCTQALHLACLALGIGEHDEVILPSLSFVATANCVLYCGANPVFADIFGNHDLTISPQEIEKKITAKTRAIIMMHYGGYACQIEEILEIARKNRLAVIEDAAHAPGAVFANRHVGTWGDVGCYSFFSNKNLVTGEGGMLVTDRDDVAERVKQLRSHGMTSLTWDRHRGHAYTYDVMALGYNYRIDEIRSALGLAQLRKLEGNNARRRYLTDIYRQRLSEGEFFGIETPFLSNACLPACHLFPILLPAAADRQELITGLRKRGIQTSIHYPPIHLFSYYQQRFPGIQLPQTEQVAARELTLPLYPMMSEADVGYVLDGVCEEMRQAVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X2M2</accession>
    <name>A0A0P6X2M2_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_09935</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the myoviridae tail sheath protein family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76909.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062846.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_09935"/>
    <dbReference type="EnsemblBacteria" id="KPL76909">
        <property type="protein sequence ID" value="KPL76909"/>
        <property type="gene ID" value="ADN00_09935"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2448"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035089">
        <property type="entry name" value="Phage_sheath_subtilisin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020287">
        <property type="entry name" value="Tail_sheath_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04984">
        <property type="entry name" value="Phage_sheath_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17482">
        <property type="entry name" value="Phage_sheath_1C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Phage_sheath_1" evidence="2">
        <location>
            <begin position="283"/>
            <end position="431"/>
        </location>
    </feature>
    <feature type="domain" description="Phage_sheath_1C" evidence="3">
        <location>
            <begin position="432"/>
            <end position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF17482"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL76909.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="546" mass="59994" checksum="6A8D5C56E0DA70BA" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="21" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X2U4</accession>
    <name>A0A0P6X2U4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Peptide ABC transporter ATP-binding protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_10830</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL77046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063013.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_10830"/>
    <dbReference type="EnsemblBacteria" id="KPL77046">
        <property type="protein sequence ID" value="KPL77046"/>
        <property type="gene ID" value="ADN00_10830"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2644"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015833">
        <property type="term" value="P:peptide transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013563">
        <property type="entry name" value="Oligopep_ABC_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08352">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR01727">
        <property type="entry name" value="oligo_HPY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3 4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0813">Transport</keyword>
    <feature type="domain" description="ABC transporter" evidence="5">
        <location>
            <begin position="5"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="41"/>
            <end position="48"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL77046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="329" mass="36250" checksum="83F368E4B0D5A236" modified="2016-01-20" version="1">MADLLNVQGLETQFKTREGIVHAVNGVSFRLKEGETLGIVGESGCGKSVTVMSMLSLIPTPPGKVVAGTAHYQGKDLIKMSAEEIRHIRGSQISLVFQDPMTSFNPVLTIGRQVAEPLEIHNGVSRQQAFDRAAEMLEMVGIPKAKERLNDYPHQFSGGMRQRVMIAMALICTPQILIADEPTTALDVTIQAQIVELVKRLRDELGMAIIWITHDLGIIAGLADRVMVMYAGLVIEEANVKDLYANPQHPYTLGLLGSLPRVDQRKEERLISIDGLPPVLMERPNFCPFAPRCTYAVERCWKENPTLASVGSEHNVACWVDPKTGSERS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X346</accession>
    <name>A0A0P6X346_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_08865</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77247.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77247">
        <property type="protein sequence ID" value="KPL77247"/>
        <property type="gene ID" value="ADN00_08865"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL77247.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="59" mass="6791" checksum="AFC5971A95AC4A7E" modified="2016-01-20" version="1">MLLVCNLNPSCHLGMNFENLWEVGIRQGIFHSQRKLVIKPVSPQFSKTLVFLFKHPLAI</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X554</accession>
    <name>A0A0P6X554_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">5-methylthioadenosine/S-adenosylhomocysteine deaminase</fullName>
            <shortName evidence="1">MTA/SAH deaminase</shortName>
            <ecNumber evidence="1">3.5.4.28</ecNumber>
            <ecNumber evidence="1">3.5.4.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="primary">mtaD</name>
        <name evidence="3" type="ORF">ADN00_18275</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the deamination of 5-methylthioadenosine and S-adenosyl-L-homocysteine into 5-methylthioinosine and S-inosyl-L-homocysteine, respectively. Is also able to deaminate adenosine.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H(+) + H2O + S-adenosyl-L-homocysteine = NH4(+) + S-inosyl-L-homocysteine</text>
            <dbReference type="Rhea" id="RHEA:20716"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:57985"/>
            <dbReference type="EC" id="3.5.4.28"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>H(+) + H2O + S-methyl-5'-thioadenosine = NH4(+) + S-methyl-5'-thioinosine</text>
            <dbReference type="Rhea" id="RHEA:25025"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:17509"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:48595"/>
            <dbReference type="EC" id="3.5.4.31"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="1">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the metallo-dependent hydrolases superfamily. MTA/SAH deaminase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="1">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.5.4.28" evidence="1"/>
    <dbReference type="EC" id="3.5.4.31" evidence="1"/>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70013.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064488.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18275"/>
    <dbReference type="EnsemblBacteria" id="KPL70013">
        <property type="protein sequence ID" value="KPL70013"/>
        <property type="gene ID" value="ADN00_18275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090614">
        <property type="term" value="F:5'-methylthioadenosine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050270">
        <property type="term" value="F:S-adenosylhomocysteine deaminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.40.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01281">
        <property type="entry name" value="MTA_SAH_deamin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006680">
        <property type="entry name" value="Amidohydro-rel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023512">
        <property type="entry name" value="Deaminase_MtaD/DadD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011059">
        <property type="entry name" value="Metal-dep_hydrolase_composite"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032466">
        <property type="entry name" value="Metal_Hydrolase"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01979">
        <property type="entry name" value="Amidohydro_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51338">
        <property type="entry name" value="SSF51338"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51556">
        <property type="entry name" value="SSF51556"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Amidohydro-rel" evidence="2">
        <location>
            <begin position="61"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="70"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="72"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="98"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="189"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="216"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="219"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_01281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01979"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL70013.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="437" mass="47761" checksum="3DD706140E4EE71A" modified="2016-01-20" version="1">MGEAVDILVVGGEVLTQNAARERIKDGAVAIRESKIIAVGSRNDLMARFEAKEVVDASGKVVLPGLVNAHTHAAMTLFRGIADDIPLEPWLQKIWPLEKKYADAPNVALGSELAFAEMVRGGTTTAADMYWHYQAAAQAAKKVGFRLFTGIGAIDVLDNESKDSLERRTREFLEEYKKDELIRPCVQVHATYTVSRETLLLVKRIVEEYGAVFVTHASETRVEVEDVTQKTGKTPIHYLEELGLLGRRTLLAHGVHLTDEEIRLLAERKVSIAHCPSSNLKLGSGIARVADLLAAGVNMAIGTDGSASNNDLDMFEEMHLTALVQKGMKNDPTVLPAEQVLYMATMGGAIALNMDDEIGSLEAGKRADLILVGFEGLHVTPVYDAVSHLVFATKSADVEAVMINGRWVMRDQTLLTMDEAQLKADTRRLCAKMRAGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-05-25" version="29" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X6W7</accession>
    <name>A0A0P6X6W7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">ADN00_06135</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="6 7" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="6 7">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062085.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_06135"/>
    <dbReference type="EnsemblBacteria" id="KPL78801">
        <property type="protein sequence ID" value="KPL78801"/>
        <property type="gene ID" value="ADN00_06135"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of transcription, DNA-templated"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd01392">
        <property type="entry name" value="HTH_LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001387">
        <property type="entry name" value="Cro/C1-type_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000843">
        <property type="entry name" value="HTH_LacI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046335">
        <property type="entry name" value="LacI/GalR-like_sensor"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010982">
        <property type="entry name" value="Lambda_DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028082">
        <property type="entry name" value="Peripla_BP_I"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00356">
        <property type="entry name" value="LacI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13377">
        <property type="entry name" value="Peripla_BP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00354">
        <property type="entry name" value="HTH_LACI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47413">
        <property type="entry name" value="SSF47413"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53822">
        <property type="entry name" value="SSF53822"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50943">
        <property type="entry name" value="HTH_CROC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50932">
        <property type="entry name" value="HTH_LACI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <keyword evidence="1" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="HTH cro/C1-type" evidence="5">
        <location>
            <begin position="3"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="domain" description="HTH lacI-type" evidence="4">
        <location>
            <begin position="5"/>
            <end position="59"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50932"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50943"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KPL78801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="338" mass="37263" checksum="FD9A351B22F33884" modified="2016-01-20" version="1">MMAKITMQEIAEIAGVSKTAVSYAFNYPDRISKETLQKILKIAEELDFIPDPIARSMSTGIIGIIGVLVPHPLPEMLANPGFTIVLEGLGEALKEDKASLMLVPPLEGSLTRAVANASVDAFVAYDLKESRAVAQILQARRIPFVTVDTDPIQDISGVLADDISSAEQMMKLVLEKGHKNIVIIALEPLEAVEEISYRGTVHRRMMGFERALGAHQDPISMRVRSCKCTQKDAGLLFRELWQDHERPTAIVTMSDVIAMGVISEALQMGLRVPQDLAVTGFDDIPGASYFHPPLTSIYQDHYEKGRVAGDLLLKSRDSLLDKAQFVHFKTELVIRKSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X798</accession>
    <name>A0A0P6X798_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_18290</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">Belongs to the eIF-2B alpha/beta/delta subunits family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064491.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_18290"/>
    <dbReference type="EnsemblBacteria" id="KPL70016">
        <property type="protein sequence ID" value="KPL70016"/>
        <property type="gene ID" value="ADN00_18290"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2964"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016853">
        <property type="term" value="F:isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044249">
        <property type="term" value="P:cellular biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.420">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10470">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000649">
        <property type="entry name" value="IF-2B-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042529">
        <property type="entry name" value="IF_2B-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011559">
        <property type="entry name" value="Initiation_fac_2B_a/b/d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027363">
        <property type="entry name" value="M1Pi_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01008">
        <property type="entry name" value="IF-2B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="SSF100950"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00524">
        <property type="entry name" value="eIF-2B_rel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="RuleBase" id="RU003814"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL70016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="350" mass="38313" checksum="5B8DA2BDAF35C595" modified="2016-01-20" version="1">MARVDDGLAFMLRFENVARYEDGAVLILDRRIYPAKIEFVRCEDFHAVAKAIGEMVTQSGGPWFAASLGMVSAARTAKGLKAVQAKAFLDEAAYTLTHARPTTSKRMVAYVQTVVDTAWQAMEAGKDPEEAAYAFVMARMEDRYLKSRRIGEHVVSLLPDDVTILTQCFAENLIGYTLLVAQEQGKKVRLYCPETRPYLQGARLTASVAYDQGVPVTVITDNMPGYLLSKKMADVFICAADVISLDGYVVNKIGTYQIALAAHENQVPFYVLGSPSPSNPTIDTVKIEERDPQEVLHAMGVRTAKEGVMGFYPAFDITPPKLVSAVIAAEGIFSPYDLMGTFGKGAVLDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="15" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X8C3</accession>
    <name>A0A0P6X8C3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">OpuAC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_07780</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78341.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062413.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000019.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_07780"/>
    <dbReference type="EnsemblBacteria" id="KPL78341">
        <property type="protein sequence ID" value="KPL78341"/>
        <property type="gene ID" value="ADN00_07780"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3389"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043190">
        <property type="term" value="C:ATP-binding cassette (ABC) transporter complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022857">
        <property type="term" value="F:transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007210">
        <property type="entry name" value="ABC_Gly_betaine_transp_sub-bd"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04069">
        <property type="entry name" value="OpuAC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5006132902" description="OpuAC domain-containing protein" evidence="2">
        <location>
            <begin position="28"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="OpuAC" evidence="3">
        <location>
            <begin position="49"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL78341.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="366" mass="40448" checksum="8A94783F8530DB4B" modified="2016-01-20" version="1">MQKRTFSWMLILIAAAMLLAACQPTAAVNESGAAPASQPSAAAEEKEVIRFGDQQWDTLWINNAIAGYIIEHGYGYPVETIELTTPVALQSIETGDIDVIMELWRANIMEWYNRVTTEGVVVDLGNSFDVSTQGWYVPRYVIEGDAERGIEPLAPDLKTVYDLANYTEVFQDREDPSKGVFVNAITGWQVAEVNRAKFKAYGLLDLYNFQEPGSSGALDAAIAGAYKKGEPVLAYYWEPTWLMGTYDMVLLEEPAYNDECWAEISQYVEGTISLDEVTETSGCAFETTGIHKGVNAGLIERAPEVTDFLEAMEIPTPLLNELAAYLASDDAIDADDTAVYFLQNHADLWMEWVPEETAAAVQAALE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X947</accession>
    <name>A0A0P6X947_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_12340</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063318.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76121">
        <property type="protein sequence ID" value="KPL76121"/>
        <property type="gene ID" value="ADN00_12340"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="87"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="109"/>
            <end position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="188" mass="21006" checksum="7BFEB3025A0CE44C" modified="2016-01-20" version="1">MTSSDEVVITCPVCGNNTRVYKVTKIFVESLEGNRLKETADERLDPSVSAHAGNKVSGSEAMRKLSKRFGPPTKRLVQPRGLHPDQVVLVMSFLALVLLWHIFTQQRGALLPALGVFAAAITLYAMNRKRLLAKHGEQHEEVQRDKKEIERATERWGETYYCAVDDVVFIAGSSEAVPADEMMNMLFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="9" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6X9T0</accession>
    <name>A0A0P6X9T0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_10320</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000024">
        <property type="protein sequence ID" value="KPL76968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062921.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000024.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL76968">
        <property type="protein sequence ID" value="KPL76968"/>
        <property type="gene ID" value="ADN00_10320"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL76968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="200" mass="23562" checksum="5CEFA2F5C80CD8DC" modified="2016-01-20" version="1">MNQYPIRKLEEQFEPNQVKRIRTLQGDISKITLIGGAGENYRIEVLYALEAGLLLASLNLVCSLLELFVRDLLIYSECQRNQGRLNYEKDFILRETNIENSKKPRWDFKPMIDVLKEQNLIQDNDASEIKEFYDQVRIPIQHGLSQRFTNIHDPSITEIEQLLQTRSLRFYNFEGLIEDKSLQLIELAVAFMLIYGHHFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2021-09-29" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XAT3</accession>
    <name>A0A0P6XAT3_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_09245</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000023">
        <property type="protein sequence ID" value="KPL77361.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77361">
        <property type="protein sequence ID" value="KPL77361"/>
        <property type="gene ID" value="ADN00_09245"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.4083"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015074">
        <property type="term" value="P:DNA integration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017895">
        <property type="entry name" value="HTH_IS408/IS1162_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001584">
        <property type="entry name" value="Integrase_cat-core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00665">
        <property type="entry name" value="rve"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50532">
        <property type="entry name" value="HTH_IS408"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50994">
        <property type="entry name" value="INTEGRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HTH IS408-type" evidence="1">
        <location>
            <begin position="4"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="domain" description="Integrase catalytic" evidence="2">
        <location>
            <begin position="127"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL77361.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="501" mass="57851" checksum="5384DE8641176CA4" modified="2016-01-20" version="1">MRKIREVIRLHFEAGLSNRAAARASQVSNSTVGEYLERAKKAGLSWPLPEGLSDEELYRRLYPEESLSRRETERPMPNWEEVHRELSKRGVTLTLLWQEYREKHPDGYGFTQFRVYYQRWNKAHTNTMRLPHKAGEEMQVDYAGMMVAITNPETGEISRAVVFVATLPASSYTYAEIQPSQELQYWLGGHVRAFSFFGGIPQTICPDNLKSGVKTPNRYEPELNPSYQELAEYYHVAVLPARVRKPRDKAHVENGVQNVERWVLAPLRNRTFFSVGEANRAITPLLQALNQKEMQHLGKSRKELFEELDQPALRPLPVHPYEYAAWKTAKVNIDYHVAFEGHYYSVPYTLVRREVRIRATERLIAVFHKGQQVAVHPRSQVQGRFTTRSEHMPANHQFVSGMGADWLLKEAENIGPHTSAYFSAMLKSRQYPQHAYRSCLGILDLARRYTRPQVETACQDLLTAKLLSYRDLKSELERLTSQTTDTVLPAHENVRGSSYYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="25" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDU9</accession>
    <name>A0A0P6XDU9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_08470</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the sigma-70 factor family. ECF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000021">
        <property type="protein sequence ID" value="KPL77895.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075062552.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000021.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL77895">
        <property type="protein sequence ID" value="KPL77895"/>
        <property type="gene ID" value="ADN00_08470"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016987">
        <property type="term" value="F:sigma factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006352">
        <property type="term" value="P:DNA-templated transcription, initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050896">
        <property type="term" value="P:response to stimulus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProt"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039425">
        <property type="entry name" value="RNA_pol_sigma-70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014284">
        <property type="entry name" value="RNA_pol_sigma-70_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007627">
        <property type="entry name" value="RNA_pol_sigma70_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013249">
        <property type="entry name" value="RNA_pol_sigma70_r4_t2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013325">
        <property type="entry name" value="RNA_pol_sigma_r2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013324">
        <property type="entry name" value="RNA_pol_sigma_r3/r4-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43133">
        <property type="entry name" value="PTHR43133"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04542">
        <property type="entry name" value="Sigma70_r2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08281">
        <property type="entry name" value="Sigma70_r4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88659">
        <property type="entry name" value="SSF88659"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88946">
        <property type="entry name" value="SSF88946"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR02937">
        <property type="entry name" value="sigma70-ECF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Sigma70_r2" evidence="2">
        <location>
            <begin position="24"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="domain" description="Sigma70_r4_2" evidence="3">
        <location>
            <begin position="122"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF04542"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF08281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL77895.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="187" mass="21731" checksum="9391AEDCE5E32418" modified="2016-01-20" version="1">MEAISDQSAIEQAVNGSQEAFSILYERYVNRIYNYIFYRVGNAHDAEDITARVFYRAMGSITRYDNRGLPFSAWLYRIAHNLVANWYRDNARKKEVSLEEAGQFQQRSEHLEVAMVQSQENEILMKAIRSLPAERQQLIILKLVEDLSNQEIGEIMGKSEGAIKSLYHRTLISLRNRMEKIGKQSHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="16" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XDY8</accession>
    <name>A0A0P6XDY8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Carbohydrate kinase, FGGY family / carbohydrate kinase, FGGY family multi-domain protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">ADN00_14855</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="4 5" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="4 5">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FGGY kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000036">
        <property type="protein sequence ID" value="KPL73070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063818.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000036.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14855"/>
    <dbReference type="EnsemblBacteria" id="KPL73070">
        <property type="protein sequence ID" value="KPL73070"/>
        <property type="gene ID" value="ADN00_14855"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1833"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016773">
        <property type="term" value="F:phosphotransferase activity, alcohol group as acceptor"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005975">
        <property type="term" value="P:carbohydrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016310">
        <property type="term" value="P:phosphorylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043129">
        <property type="entry name" value="ATPase_NBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000577">
        <property type="entry name" value="Carb_kinase_FGGY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018485">
        <property type="entry name" value="Carb_kinase_FGGY_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018483">
        <property type="entry name" value="Carb_kinase_FGGY_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018484">
        <property type="entry name" value="Carb_kinase_FGGY_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02782">
        <property type="entry name" value="FGGY_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00370">
        <property type="entry name" value="FGGY_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000538">
        <property type="entry name" value="GlpK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53067">
        <property type="entry name" value="SSF53067"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00445">
        <property type="entry name" value="FGGY_KINASES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FGGY_N" evidence="2">
        <location>
            <begin position="5"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="domain" description="FGGY_C" evidence="3">
        <location>
            <begin position="296"/>
            <end position="460"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003733"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KPL73070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="520" mass="57647" checksum="E0D92D843BCF8DD4" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XE05</accession>
    <name>A0A0P6XE05_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Membrane protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">ADN00_14970</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="7 8" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="7 8">P3M-1</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000036">
        <property type="protein sequence ID" value="KPL73088.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063840.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000036.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_14970"/>
    <dbReference type="EnsemblBacteria" id="KPL73088">
        <property type="protein sequence ID" value="KPL73088"/>
        <property type="gene ID" value="ADN00_14970"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1857"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016627">
        <property type="term" value="F:oxidoreductase activity, acting on the CH-CH group of donors"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001104">
        <property type="entry name" value="3-oxo-5_a-steroid_4-DH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010721">
        <property type="entry name" value="DUF1295"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32251">
        <property type="entry name" value="PTHR32251"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06966">
        <property type="entry name" value="DUF1295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50244">
        <property type="entry name" value="S5A_REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="7"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="36"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="102"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="134"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="196"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="domain" description="S5A_REDUCTASE" evidence="6">
        <location>
            <begin position="143"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KPL73088.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="264" mass="30415" checksum="BD7EB38DAB227B6E" modified="2016-01-20" version="1">MGIQQAVLLTGVFIFAYMTAIWVASLALKNTSIVDIFWGLGFVLTAWLVFMVASPMSWAQVLLLILVSVWGLRLSIYIFIRNRNKPEDFRYRAWREEHGKSWWWYSYFQTFILQGVLMWMISTPLTAAMISTQPGILPLVIAGGLVWLYGFYFETAGDAQLSRFKANPENKGKVLNTGVWRYTRHPNYFGDAAQWWGYYLIAASLGAFWSVFSPILMTVLLLRVSGVALLEKTLKETKPQYKEYIETTSSFFPWFPKHPSNPNE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XEY2</accession>
    <name>A0A0P6XEY2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NACHT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_14275</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000034">
        <property type="protein sequence ID" value="KPL73734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063705.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000034.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL73734">
        <property type="protein sequence ID" value="KPL73734"/>
        <property type="gene ID" value="ADN00_14275"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007111">
        <property type="entry name" value="NACHT_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007421">
        <property type="entry name" value="Schlafen_AlbA_2_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04326">
        <property type="entry name" value="AlbA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="SSF52540"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50837">
        <property type="entry name" value="NACHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NACHT" evidence="1">
        <location>
            <begin position="253"/>
            <end position="408"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL73734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="729" mass="84828" checksum="ABB692481538B175" modified="2016-01-20" version="1"> </sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="19" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XG74</accession>
    <name>A0A0P6XG74_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidase_M24 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">ADN00_18665</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="5 6" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="5 6">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="3">Belongs to the peptidase M24B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000045">
        <property type="protein sequence ID" value="KPL70072.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064553.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000045.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL70072">
        <property type="protein sequence ID" value="KPL70072"/>
        <property type="gene ID" value="ADN00_18665"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029149">
        <property type="entry name" value="Creatin/AminoP/Spt16_NTD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036005">
        <property type="entry name" value="Creatinase/aminopeptidase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000994">
        <property type="entry name" value="Pept_M24"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001131">
        <property type="entry name" value="Peptidase_M24B_aminopep-P_CS"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00557">
        <property type="entry name" value="Peptidase_M24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53092">
        <property type="entry name" value="SSF53092"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55920">
        <property type="entry name" value="SSF55920"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00491">
        <property type="entry name" value="PROLINE_PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase_M24" evidence="4">
        <location>
            <begin position="161"/>
            <end position="390"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU000590"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00557"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KPL70072.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="412" mass="45675" checksum="F707533B8FDBA30D" modified="2016-01-20" version="1">MKQELDALMQVENVDALMVLGAGFHNPYMVYLTGGGHLTQALVIKKRGQSPVLFHESMERGEAQKTGLKTVNLKNYPAAVYLQECGGDHLKASARRMEKILQDFHLTEGRVALFGEQDAGLTASLFAELRVRMPALEFFGASRGGILMRAMATKDETELARIRRVGQATARVVGNTADFLSGCPVKAGALVNRDGSPVTIGQVKRKINLWLMEEGMENPEATIFAIGRDAALPHSSGTDSDLLQLGKTIVFDIFPCEEGGGYFHDFTRTWCLGHAPDEVLRLYEQVLDVYQRVTHALTVDTPFSAYQKLVCEWFEEMGHKTVLSEPATEEGYVHGLGHGVGLHVHELPFYTPSEGNENMLRPGNVIAVEPGLYYPDLSMGVRLEDTYWIDDHGSFQTFVDYPRDLILPVKQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="18" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGA1</accession>
    <name>A0A0P6XGA1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">SgcQ protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05485</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BtpA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000016">
        <property type="protein sequence ID" value="KPL78700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061968.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000016.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_05485"/>
    <dbReference type="EnsemblBacteria" id="KPL78700">
        <property type="protein sequence ID" value="KPL78700"/>
        <property type="gene ID" value="ADN00_05485"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1572"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005137">
        <property type="entry name" value="BtpA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21381">
        <property type="entry name" value="PTHR21381"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03437">
        <property type="entry name" value="BtpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005956">
        <property type="entry name" value="BtpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="SSF51366"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00259">
        <property type="entry name" value="thylakoid_BtpA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL78700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="269" mass="29072" checksum="D165FB709C492BC8" modified="2016-01-20" version="1">MTWIKELFGVEKPVIAMCHLLAMPGDPGYDSAAGVAGVVRRARADLLALQEGGVDALMFSNEASLPYLTKVEPVTGMTMARVIGELLHEVKLPFGVNVLWDPFASIDLAAATGAKFVREIFTGVYASDFGLWNTNCGEVVRHQQHIHAQGVKLLFNIVPEAARYLADRDIVEVARSTVFNARPDGLCVSGLTAGAETDASVLAKVKQAVPQTPVFANTGVRLENVEQQLAVADGAVVGTTFKRDGTIWNEVDAARVKALMERVRSIRQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="14" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XGE1</accession>
    <name>A0A0P6XGE1_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">ADN00_13620</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="3 4" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="3 4">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000032">
        <property type="protein sequence ID" value="KPL74337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063574.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000032.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_13620"/>
    <dbReference type="EnsemblBacteria" id="KPL74337">
        <property type="protein sequence ID" value="KPL74337"/>
        <property type="gene ID" value="ADN00_13620"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.1300"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031167">
        <property type="term" value="P:rRNA methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004398">
        <property type="entry name" value="RNA_MeTrfase_RsmD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF004553">
        <property type="entry name" value="CHP00095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="SSF53335"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00095">
        <property type="entry name" value="TIGR00095"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KPL74337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="192" mass="21676" checksum="E4F3F9EC65749C6D" modified="2016-01-20" version="1">MSNPRIIAGKARGLRIQSVPGDTTRPITDRVKEALFNIIGQDIVDAHFFDLFGGTGSVGIEALSRGAAYVRFSDMARAAVTTIKANLQHTRLEANAQVIFGDAFALLKQKPDHRFDYLYIAPPQYKQLWVRALREVDANPGWMDPSGWVIVQIHPVEYEEVPLEHFVEFDQRKYGSTLLIFYEFKKSDSSST</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XMQ2</accession>
    <name>A0A0P6XMQ2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Acetyltransf_6 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_11035</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000025">
        <property type="protein sequence ID" value="KPL76499.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063068.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000025.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11035"/>
    <dbReference type="EnsemblBacteria" id="KPL76499">
        <property type="protein sequence ID" value="KPL76499"/>
        <property type="gene ID" value="ADN00_11035"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.901"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038740">
        <property type="entry name" value="BioF2-like_GNAT_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13480">
        <property type="entry name" value="Acetyltransf_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="SSF55729"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Acetyltransf_6" evidence="1">
        <location>
            <begin position="177"/>
            <end position="321"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL76499.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="338" mass="38206" checksum="480EC7D72A5E3FAB" modified="2016-01-20" version="1">MIFELHTVFPQGLAEEWNDLLDRSITKVPFLRYEYLSGWWDTRGGGEWPRAELRLVTARQDGRLAGAAALMQARHKGQPALMLVGSIEISDYLDLVVEEKNLPAFAEGLLAFLRSPAFPGGWERLSLYNIPDDSPSLAALQAAARSTGAVISAEAVSPCPYITLPGDWESYLTGIDKKQRHEIRRKIRRAESAEQPVKLYVSSAPERIEQDIEDCMRLMAMDAEKERFLSPAMRVQFKNCLNRAFEGGYLQLAFLEVGGEKAAVYANFLFNRRVLVYNSGMDTAFSEVSPGWVLLGYLLQGAIEQGMQEFDFMRGNEDYKYRFGAVDRHVLRVDLQFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-01-19" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XPQ9</accession>
    <name>A0A0P6XPQ9_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_17655</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000042">
        <property type="protein sequence ID" value="KPL71225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075064374.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000042.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_17655"/>
    <dbReference type="EnsemblBacteria" id="KPL71225">
        <property type="protein sequence ID" value="KPL71225"/>
        <property type="gene ID" value="ADN00_17655"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.2797"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019660">
        <property type="entry name" value="Put_sensory_transdc_reg_YbjN"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10722">
        <property type="entry name" value="YbjN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL71225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="152" mass="17490" checksum="CE0B9CC7238D925B" modified="2016-01-20" version="1">METLFETVVRYFTQEEWYFLKMDSRPTLQMSFNGSNGKWLCNANVNEEKGFFSFYSVCPINVPEERRATVAEFLTRANYGLMIGNFEMDYRDGEVRYKTSLDVENSEINLSLIGNLVNVNLLMMDRYLPGILMCIYGNETAEAAIHSIEGEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="4" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XRE4</accession>
    <name>A0A0P6XRE4_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_15540</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72231.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72231">
        <property type="protein sequence ID" value="KPL72231"/>
        <property type="gene ID" value="ADN00_15540"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72231.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="73" mass="7808" checksum="AB9AEC2FE2478AB4" modified="2016-01-20" version="1">MLLDLKVVNQILNSEPAGNVSLMAIPGNRPAVIVQTPNGQKIILTPDMARQLAKQLSPMADLAQPNLENGYGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="10" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XRI0</accession>
    <name>A0A0P6XRI0_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_15745</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000039">
        <property type="protein sequence ID" value="KPL72268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL72268">
        <property type="protein sequence ID" value="KPL72268"/>
        <property type="gene ID" value="ADN00_15745"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL72268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="77" mass="8668" checksum="5909D7CC4C310DEC" modified="2016-01-20" version="1">MDLNQKKINPINNRPICPVCGSELVLTLIVFGNVKYHAWLCDCATQPEDVAADIVRAREFAGEVLLYTVEYVRDEGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="12" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XSF7</accession>
    <name>A0A0P6XSF7_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_02350</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000010">
        <property type="protein sequence ID" value="KPL79659.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061353.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000010.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79659">
        <property type="protein sequence ID" value="KPL79659"/>
        <property type="gene ID" value="ADN00_02350"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="SSF56281"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL79659.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="289" mass="32341" checksum="55C21861142FABC1" modified="2016-01-20" version="1">MQEIAPKIYIETGFPGVTLGAINWPHGLILIDAPFRAEDARSWRSALLNLGGGVDRILVNLDDHLDRVIGVRNMDCTVVAHASIADNICARPATFRPQPVGSGAEWEQFGGLGTVRWALPEISFNEQLEIYWDTEANPLVLQHHPGPSNGSIWAILPDHQIIFVGDTVTPGEPPFLECADLPAWIKSVERLKSDEFNTHVMISSRSGIIHAADLKAQHAYLTLLHERMEELAQKKAAPEKTESLIPELLKEFHISPEKEILYQQRLAYGLRQYYVRTYLHNSADPGFVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2019-12-11" version="7" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6XYS5</accession>
    <name>A0A0P6XYS5_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">ADN00_07470</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="1 2" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="1 2">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000019">
        <property type="protein sequence ID" value="KPL78356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL78356">
        <property type="protein sequence ID" value="KPL78356"/>
        <property type="gene ID" value="ADN00_07470"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008930">
        <property type="entry name" value="Terpenoid_cyclase/PrenylTrfase"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48239">
        <property type="entry name" value="SSF48239"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KPL78356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="284" mass="32126" checksum="3C2F426C9516A40B" modified="2016-01-20" version="1">MLAHPVVQNLILQAENWPNQPLKRHNDASHPLHVLGVLADFGLKKSDPGISDLVEKITAHSSPQGLLQTLLHVSPRYGGSAEPQWSWMLCDLPLILHALMAFGLNNHPLIQTNLNHLLSLVRDNGWPCACDSAWQGFRGPGRKDDPCPYATLISLRAFSLLPETHTWPEVQAGVDMLLNHWQMRKEKKYYLFGIGSDFGKLKYPLIWYDLLHILTVLSRFENARRDPRLQEMAALLASQKDPNGCFTPTSVWMAWKGWDFAQKKEPSPWLTLLSHRALSAIAHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="13" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y2Q8</accession>
    <name>A0A0P6Y2Q8_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_05015</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000015">
        <property type="protein sequence ID" value="KPL79206.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061857.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000015.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79206">
        <property type="protein sequence ID" value="KPL79206"/>
        <property type="gene ID" value="ADN00_05015"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="7"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79206.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="208" mass="22940" checksum="A58C53C7DCB97FA1" modified="2016-01-20" version="1">MYRRNSWIVTAAAITSFLVVIIFLNFHVTNRVSETNFYSKEGAQASDVLRLPHNQVPLAVVINGSGLIADALREELARLVAEDQELNRAVVLLQPGQNPAGMPTLEVDLVPHGIVWTPVMSFASIEWRVRFTDADNQSAGVAIQPMHVSMKASSSLLGSLWLRESSLGIMTWRGYRDSLGRLAAQNLNKVLVEYVANRPLAQLSFAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="20" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y2Y2</accession>
    <name>A0A0P6Y2Y2_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="2 7">30S ribosomal protein S20</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="primary">rpsT</name>
        <name evidence="9" type="ORF">ADN00_11630</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="9 10" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="9 10">P3M-1</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Binds directly to 16S ribosomal RNA.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the bacterial ribosomal protein bS20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000026">
        <property type="protein sequence ID" value="KPL76007.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075063186.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000026.1"/>
    </dbReference>
    <dbReference type="STRING" id="1134406.ADN00_11630"/>
    <dbReference type="EnsemblBacteria" id="KPL76007">
        <property type="protein sequence ID" value="KPL76007"/>
        <property type="gene ID" value="ADN00_11630"/>
    </dbReference>
    <dbReference type="PATRIC" id="fig|1134406.4.peg.3801"/>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019843">
        <property type="term" value="F:rRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00500">
        <property type="entry name" value="Ribosomal_S20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002583">
        <property type="entry name" value="Ribosomal_S20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036510">
        <property type="entry name" value="Ribosomal_S20_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33398">
        <property type="entry name" value="PTHR33398"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01649">
        <property type="entry name" value="Ribosomal_S20p"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46992">
        <property type="entry name" value="SSF46992"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="TIGRFAMs" id="TIGR00029">
        <property type="entry name" value="S20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="5 7 9" id="KW-0689">Ribosomal protein</keyword>
    <keyword evidence="4 7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3 7" id="KW-0699">rRNA-binding</keyword>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="44"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007634"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00015666"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022730"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_00500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KPL76007.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="87" mass="9848" checksum="4A7BDD38F5E4AC4F" modified="2016-01-20" version="1">MANIKSAIKRNKQNEKKRVRNRVYRGTARTFIKKARLAIEAGEKETAEALVRQAVSALDKAAEKGVLHKNNASRRKSRLMKQLAAME</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2020-10-07" version="11" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6Y354</accession>
    <name>A0A0P6Y354_9CHLR</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_03130</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000014">
        <property type="protein sequence ID" value="KPL79334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061503.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000014.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79334">
        <property type="protein sequence ID" value="KPL79334"/>
        <property type="gene ID" value="ADN00_03130"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016021">
        <property type="term" value="C:integral component of membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="6"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="32"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="71"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="100"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="142"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="183"/>
            <end position="206"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="226" mass="23850" checksum="BE50AEF67D46A656" modified="2016-01-20" version="1">MQMLDPVWTITSFALTVLVLSFLLGDNPLFRLVSYLFVGVSAGFAAVMLVYQVILPRLVWPLLEGSPAERALAVIPLVLSVLLLARLVPRLAVVGSLPMGYLVGAGAAVMISGAVMGTLVRQTLSAIQVFDLSAAAPSQNPVLQFAEAAVMLTGTVGTLAYFQFTARAKPNQPAQRPAWVNGLARVGEVFIAITLGALFAGVYAAALSALIDRLEFILQVIQGLIG</sequence>
</entry>
<entry dataset="TrEMBL" created="2016-01-20" modified="2022-08-03" version="17" xmlns="http://uniprot.org/uniprot">
    <accession>A0A0P6YBQ3</accession>
    <name>A0A0P6YBQ3_9CHLR</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RCK N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">ADN00_03245</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Ornatilinea apprima</name>
        <dbReference type="NCBI Taxonomy" id="1134406"/>
        <lineage>
            <taxon>Bacteria</taxon>
            <taxon>Chloroflexi</taxon>
            <taxon>Anaerolineae</taxon>
            <taxon>Anaerolineales</taxon>
            <taxon>Anaerolineaceae</taxon>
            <taxon>Ornatilinea</taxon>
        </lineage>
    </organism>
    <reference evidence="2 3" key="1">
        <citation type="submission" date="2015-07" db="EMBL/GenBank/DDBJ databases">
            <title>Genome sequence of Ornatilinea apprima DSM 23815.</title>
            <authorList>
                <person name="Hemp J."/>
                <person name="Ward L.M."/>
                <person name="Pace L.A."/>
                <person name="Fischer W.W."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]</scope>
        <source>
            <strain evidence="2 3">P3M-1</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="LGCL01000014">
        <property type="protein sequence ID" value="KPL79353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="RefSeq" id="WP_075061522.1">
        <property type="nucleotide sequence ID" value="NZ_LGCL01000014.1"/>
    </dbReference>
    <dbReference type="EnsemblBacteria" id="KPL79353">
        <property type="protein sequence ID" value="KPL79353"/>
        <property type="gene ID" value="ADN00_03245"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000050417">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006813">
        <property type="term" value="P:potassium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003148">
        <property type="entry name" value="RCK_N"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02254">
        <property type="entry name" value="TrkA_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="SSF51735"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51201">
        <property type="entry name" value="RCK_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RCK N-terminal" evidence="1">
        <location>
            <begin position="6"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KPL79353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000050417"/>
        </source>
    </evidence>
    <sequence length="241" mass="26858" checksum="C64266A496E2FDCA" modified="2016-01-20" version="1">MEKKLNVVVIGDSTFSWSMVNALRKKISGHLYFLLPERDQAVEASLLENVVAISGNPSDPEVLDQLDLENCHTFIAGSREDDTNVLCALYARNKGAKNIYARVFETRFAALFESVGIVPIQTSETAAAFLSIRILKPDVADLVDLAEGQFDLDEIDVARVPELVGCRLGNLQSDFLNTIAIAKEGKTHLGYKTLVEEGSKVLVIYERSLGKEVLKELRRVARVAKEHANRLDRDNWPMLDE</sequence>
</entry>
<copyright>
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms Distributed under the Creative Commons Attribution (CC BY 4.0) License
</copyright>
</uniprot>